Table 5.2 Properties of six different caging groups.
Caging Group | Uncaging Rate * | Photolysis Quantum Yield * | Inertness of Photolysis By-product | Confers Water Solubility | Long-Wavelength Absorption (≥360 nm) |
---|---|---|---|---|---|
CNB | ++++ | +++++ | +++++ | +++++ | ++ |
NPE | +++ | +++ | +++ | + | ++ |
DMNPE | +++ | +++ | +++ | + | +++++ |
DMNB | +++ | +++ | ++ | + | +++++ |
CMNB | +++ | +++ | + | ++++ | +++ |
NP | +++ | +++ | + | + | ++ |
+++++ = Optimal response. + = Poor response. * Both the structure of the nitrobenzyl moiety and the atom to which it is attached have some effect on the efficiency and wavelength required for uncaging. |
For Research Use Only. Not for use in diagnostic procedures.