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Table 7.6 Binding profiles of protein A and protein G.
| Antibody |
Protein A
|
Protein G
|
|---|---|---|
| Bovine |
+
|
++
|
| Cat |
++
|
–
|
| Chicken |
–
|
–
|
| Dog |
++
|
+
|
| Goat |
+
|
++
|
| Guinea pig |
+
|
++
|
| Horse |
–
|
++
|
| Human IgG1, IgG2, IgG4 |
++
|
++
|
| Human IgG3 |
–
|
++
|
| Human IgM, IgA, IgE |
++
|
–
|
| Human IgD |
–
|
–
|
| Mouse IgG1 |
–
|
++
|
| Mouse (others) |
++
|
++
|
| Pig |
++
|
++
|
| Rabbit |
++
|
++
|
| Rat |
–
|
+
|
| Sheep |
–
|
++
|
| + Moderate binding. ++ Strong binding. – Weak or no binding. | ||
For Research Use Only. Not for use in diagnostic procedures.