Chromeleon University
Here’s a collection of resources to learn about the feature sets that make the Thermo Scientific Chromeleon Chromatography Data System (CDS) both powerful and easy to use.
What can you get from high pressure ion chromatography?
A new level of performance. We made sure each component of our IC systems was built to operate with ease at high backpressures. The speed and resolution achieved from Thermo Scientific Dionex HPIC systems was worth the effort.
On this page
- What is high pressure ion chromatography?
- Why develop high pressure ion chromatography capabilities?
- How can I balance of resolution and speed in my Dionex HPIC system?
- What Dionex HPIC systems are available?
- What 4μm particle size IC columns are available?
- Can I use other particle size columns with HPIC instruments?
What is high pressure ion chromatography?
Dionex HPIC systems redefine the way ion chromatography is performed due to their continuous operation at up to 5000 psi when configured as a Reagent-Free IC (RFIC) system. This feature allows for the use of high-efficiency 4μm particle-size columns, which provide better performance.
Many of our customers need higher resolution, and one can get significant gains in resolution by reducing an IC column’s particle size. While column efficiency doubles by reducing the particle size from 8µm to 4µm, the smaller particle size increases the column pressure four-fold. Dionex HPIC were designed to operate comfortably at these higher backpressures.
Featured column video
Learn about Thermo Scientific Dionex IonPac 4µm IC columns, their features, and applications.
Our 4µm columns are available in microbore (2 mm) and standard bore (4 mm) inner diameters. Different lengths allow you to choose the optimum balance between resolution and throughput.
- Use the longer, 250 mm length 4µm particle size columns for higher resolution separations of complex sample matrices.
- Use the shorter, 150 mm length 4µm particle size columns at higher flow rates to increase productivity without sacrificing performance.
| Integrated, plug-and-play high pressure ion chromatography systems | |
|---|---|
| Dionex Inuvion Core IC System | Perform reliable, day-to-day ion analysis while maintaining low operating costs |
| Dionex Inuvion IC System | Simplify your ion analysis with this configurable IC system that has the option to add Reagent-Free IC eluent generation. |
| Dionex Integrion HPIC System | Meet your routine ion analysis demands using the easy-to-use, reliable, integrated IC system |
| Modular, highly configurable high pressure ion chromatography systems | |
| Dionex ICS-6000 Standard Bore and Microbore HPIC Systems | Get significant increases in resolution and throughput in this high-pressure modular IC system for standard bore and microbore columns |
Thermo Scientific Dionex IonPac and Thermo Scientific Dionex CarboPac 4 μm Particle-size IC Columns
| IC Column | Application | Format |
| Dionex IonPac AS32-Fast-4µm | Fast analysis of polarizable anions with a simple, isocratic eluent | Standard and microbore |
| Dionex IonPac AS29-Fast-4µm | Fast analysis of inorganic anions in drinking water | Standard and microbore |
| Dionex IonPac AS28-Fast-4µm | Fast, high-resolution of trace concentrations of low molecular weight organic acids (glycolate, acetate) and inorganic anions | Standard, microbore, and capillary |
| Dionex IonPac AS23-4µm | High-resolution separation of oxyhalides and inorganic anions in diverse matrices | Standard and microbore |
| Dionex IonPac AS22-Fast-4µm | Fast high resolution separation of common inorganic anions | Standard and microbore |
| Dionex IonPac AS19-4µm | High-resolution separation of oxyhalides and inorganic anions in complex sample matrices | Standard, microbore, and capillary |
| Dionex IonPac AS18-4µm | Fast, high-resolution separation of inorganic anions in diverse matrices | Standard, microbore, and capillary |
| Dionex IonPac AS11-HC-4µm | High-resolution separation of organic acids and inorganic anions in complex sample matrices | Standard, microbore, and capillary |
| Dionex IonPac CS21-Fast-4µm | Determination and quantitation of cationic polar pesticides in food and beverages using IC-MS/MS and IC-HRAM-MS | Microbore |
| Dionex IonPac CS19-4µm | Fast, high-resolution separation of cations and small polar amines in diverse matrices | Standard, microbore, and capillary |
| Dionex IonPac CS16-Fast-4µm | Fast, high-resolution separation of short chain amines and disparate ratios of sodium and ammonium | Standard and microbore |
| Dionex IonPac CS16-4µm | High-resolution separation of short chain amines and disparate ratios of sodium and ammonium | Standard, microbore, and capillary |
| Dionex IonPac CS12A-5µm | High-efficiency and fast analysis of mono- and divalent cations | Standard, microbore, and capillary |
| Dionex CarboPac PA300-4µm IC Columns | Accurate, high-efficiency and high-resolution separations of charged and neutral glycans in complex hetrogenous biological and food samples | Microbore |
| Dionex CarboPac PA210-Fast-4µm IC Columns | High-resolution analysis of mono-, di-, tri-, tetra- and pentasaccharides in various types of food samples | Standard and microbore |
| Dionex CarboPac PA20-Fast-4µm IC Columns | Fast and efficient analysis of monosaccharides for therapeutics and food and beverage samples | Microbore |
| Dionex CarboPac SA10-4µm IC Columns | High-resolution, fast and high-capacity separation of mono-and disaccharides in biofuels, foods, and beverages. | Standard and microbore |
Yes, of course. Most IC column chemistries can be run on HPIC instruments. Basic column compatibility with instruments is as follows:
- Standard bore and microbore columns (2–5 mm ID) are for use on the Dionex Inuvion Core IC system, Dionex Inuvion IC system, Dionex Integrion HPIC system or the Dionex ICS-6000 HPIC system.
- Applications using gradient separations with two or more eluent solutions on standard bore and microbore columns are run on the Dionex ICS-6000 HPIC system configured for gradient separations.
- Other HPIC systems support isocratic separations or gradient separations achieved by eluent generation.
Resources
Style Sheet for Global Design System
Style Sheet for Komodo Tabs
CMD SchemaApp code