Find SNPs, indels, and CNVs associated with disease risk in large cohorts
Large-scale genotyping studies aimed at improving understanding of the genetic factors of disease risk and drug response are helping to pave the way toward precision medicine. Multi-year cohort studies and global and regional research screening initiatives are working to identify genetic effects in many different populations through genotyping analysis. To be successful, these studies require high-density SNP genotyping arrays that can provide highly accurate imputation, deliver reproducible results, and help ensure there is no loss of SNP markers from lot to lot.
Applied Biosystems now offers a family of genotyping microarrays covering SNPs, indels, and CNVs for precision medicine research and multi-population genomic studies which are highly affordable, contain high-value functional and clinical research content, and offer easy customization—all without large sample number commitments.
The Axiom Precision Medicine Diversity Array (PMDA), Axiom Precision Medicine Research Array (PMRA), and Axiom Asia Precision Medicine Research Array (Asia PMRA) are broad, powerful genotyping analysis arrays for research into common and rare inherited diseases, genetic risk profiling, immune response, pharmacogenomics, and more. They may be customized with de novo markers or markers selected from the Applied Biosystems Axiom Genomic Database of genotype-tested markers.
Genotyping arrays for precision medicine research
Axiom PMDA
- GWAS imputation module of >800,000 markers from Phase III of the 1000 Genomes Project
- >15,000 actionable variants covering ACMG59 genes associated with familial hypercholesterolemia, breast cancer, rare genetic disorders, and others
- >5,000 pharmacogenomic biomarkers in >1,100 genes offering comprehensive coverage of core and extended ADME genes across CPIC levels 1–4
Axiom PMRA
- GWAS imputation module of 800,000 markers with broad genomic coverage across all major ancestral populations
- Highly affordable pricing with no minimum order commitments
- Customization of up to 50,000 markers
Axiom Asia PMRA
- GWAS imputation module of >540,000 markers specific to South and East Asia populations
- Highly affordable pricing with no minimum order commitments
- Customization of up to 50,000 markers
Need further customization? Check out our Applied Biosystems Axiom myDesign custom program.
Interested in broad pharmacogenomic coverage? Learn more about the Applied Biosystems PharmacoScan Solution.
Resources
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