Nalgene square bottles come in a variety of formats and materials to accommodate a wide range of application needs. Their square shape saves shelf and counter space compared with round bottles of the same volume. The wide-mouth designs are easier to fill and are recommended for solid, semi-solid and viscous liquid materials. Those with mouth openings less than 100mm are guaranteed leakproof*. Narrow-mouth bottles provide better control when pouring and all come with the liquid leakproof* guarantee.
Thermo Scientific Nalgene bottles are made only from the highest quality plastic materials that meet pharmaceutical, laboratory and food grade standards; our plastic resins are selected to minimize additives and reduce potential leachables.
Nalgene bottles are manufactured in our ISO 13485:2003 registered manufacturing facilities. Most of our plastic resin materials are DMF registered and meet a number of regulatory specifications including: USP Class VI, EP monographs, EU food-contact directives, CONEG, RoHS, CA Prop 65, SARA Title III Sec. 313, and 21 CFR pt 177. Nalgene containers are made from a wide variety of plastic types to meet the needs of virtually any laboratory application.
For help selecting the Nalgene bottle that's perfect for your lab applications, use our online selection guide. For personal assistance, contact the Nalgene technical support team. For specific material claims, please contact Nalgene Regulatory Support.
| Narrow-Mouth Square PPCO Bottle (2016-series) | Narrow-Mouth Square HDPE Bottles (2018-series) | Narrow-Mouth Square PC Bottle (2015-series) | Narrow-Mouth Square PETG Bottle (2019-series) |
| Good chemical resistance, graduated, autoclavable | Good chemical resistance, graduated | Window clear, superior impact resistance, graduated, autoclavable | Window clear, graduated, sterile |
 |  |  |  |
| PPCO bottle PP Closure | HDPE bottle PP Closure | PC bottle PP closure | PETG bottle HDPE Closure |
| Milky white translucent | Milky white translucent | Window clear | Window clear |
| 30mL–1L | 30mL–1L | 30mL–2L | 30mL–2L |
| Leakproof* | Leakproof* | Leakproof* | Leakproof* |
| Molded graduations | Molded graduations | Molded graduations | Molded graduations |
| Temp range -40oC to 121oC | Temp range -100oC to 120oC | Temp range -135oC to 135oC | Temp range -40oC to 70oC |
| Autoclavable | Not autoclavable | Autoclavable | Not autoclavable |
| Complies with Part 21 CFR 177.1520 for food use | Complies with Part 21 CFR 177.1520 for food use1 | Complies with Part 21 CFR 177.1580 for food use | Complies with Part 21 CFR 177.1315 for food use2 |
| BPA-Free | BPA-Free | contains BPA | BPA-Free |
| Phthalate-free | Phthalate-free | Phthalate-free | Phthalate-free |
General Chemical Compatibility
| Narrow-Mouth Square Lab Quality Bottle (2016-series) | Narrow-Mouth Square HDPE Bottles (2018-series) | Narrow-Mouth Square Bottle (2015-series) | Narrow-Mouth Square Bottle (2019-series) | |
| Acids, dilute or weak | E | E | E | G |
| Acids^ strong, concentrated | G | G | N | N |
| Alcohols, aliphatic | E | E | G | G |
| Aldehydes | G | G | F | G |
| Bases/alkali | E | E | N | N |
| Esters | G | G | N | F |
| Hydrocarbons, aliphatic | G | G | G | G |
| Hydrocarbons, aromatic | N | N | N | N |
| Hydrocarbons, halogenated | N | N | N | N |
| Ketones, aromatic | N | N | N | N |
| Oxidizing agents, strong | F | F | F | F |
For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.
| E | No damage after 30 days constant exposure at 20oC. |
| G | Little or no damage after 30 days constant exposure at 20oC. |
| F | Some effect after 7 days constant exposure at 20oC. |
| N | Not recommended. Immediate damage may occur. |
Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)
2. PETG is acceptable for alcoholic foods containing not more than 15% by volume alcohol; fill and storage temperature not to exceed 49oC(120oF). Nonalcoholic foods of hot fill not to exceed 82oC(180F) and 49oC(120F) in storage. Not suitable for carbonated beverages or beer or packaging food requiring thermal processing.
*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except for oxidizing acids, see "Oxidizing acids, strong."
| Wide-Mouth Square High Density HDPE Bottles (2114-series) | Wide-Mouth Square PPCO Bottle (2110-series) | Large Wide-Mouth Square HDPE Bottle (2123-series) | Large Wide-Mouth Square PPCO Bottle (2122-series) |
| Space-saving square shape, wide mouth | Space-saving square shape, wide mouth, autoclavable | Large capacity, molded hand grip | Large capacity, molded hand grip, autoclavable |
 |  |  | |
| HDPE bottle PP Closure | PPCO bottle PP closure | HDPE bottle white PP Closure | PPCO bottle white PP Closure |
| Milky white translucent | Milky white translucent | Milky white translucent | Milky white translucent |
| 60mL–1L | 60mL–1L | 4L | 4L |
| Leakproof* | Leakproof* | Not liquid leakproof | Not liquid leakproof |
| No graduations | No graduations | No graduations | No graduations |
| Temp range -100oC to 120oC | Temp range -40oC to 121oC | Temp range -100oC to 120oC | Temp range -40oC to 121oC |
| Not autoclavable | Autoclavable | Not autoclavable | Autoclavable |
| Complies with Part 21 CFR 177.1520 for food use1 | Complies with Part 21 CFR 177.1520 for food use | Complies with Part 21 CFR 177.1520 for food use1 | Complies with Part 21 CFR 177.1580 for food use |
| BPA-Free | BPA-Free | BPA-Free | BPA-free |
| Phthalate-free | Phthalate-free | Phthalate-free | Phthalate-free |
General chemical compatibility
| Wide-Mouth Square HDPE Bottles (2114-series) | Wide-Mouth Square Lab Quality Bottle (2110-series) | Large Wide-Mouth Square HDPE Bottle (2123-series) | Large Wide-Mouth Square Bottle (2122-series) | |
| Acids, dilute or weak | E | E | E | E |
| Acids^ strong, concentrated | G | G | G | G |
| Alcohols, aliphatic | E | E | E | E |
| Aldehydes | G | G | G | G |
| Bases/alkali | E | E | E | E |
| Esters | G | G | G | G |
| Hydrocarbons, aliphatic | G | G | G | G |
| Hydrocarbons, aromatic | N | N | N | N |
| Hydrocarbons, halogenated | N | N | N | N |
| Ketones, aromatic | N | N | N | N |
| Oxidizing agents, strong | F | F | F | F |
For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.
| E | No damage after 30 days constant exposure at 20 oC |
| G | Little or no damage after 30 days constant exposure at 20oC |
| F | Some effect after 7 days constant exposure at 20oC |
| N | No recommended. Immediate damage may occur |
Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)
*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except for oxidizing acids, see "Oxidizing acids, strong."
| Wide-Mouth PPCO Dilution Bottle | Wide-Mouth PSF Dilution Bottle | Narrow-Mouth PSF Dilution Bottle |
| Better chemical resistance, less accurate | Better accuracy and clarity, higher temp range | Better accuracy and clarity, higher temp range |
 |  |  |
| PPCO bottle PP Closure | PSF bottle PP Closure | PSF bottle PP closure |
| Milky white translucent | Transparent, yellow tint | Transparent, yellow tint |
| Brim capacity 220mL | Brim capacity 220mL | Brim capacity 210mL |
| Capacity to neck 205mL | Capacity to neck 205mL | Capacity to neck 200mL |
| Cap size 38mm | Cap size 38mm | Cap size 28mm |
| Wide mouth | Wide mouth | Narrow mouth |
| Leakproof* | Leakproof* | Leakproof* |
| Graduations at 90mL and 99mL | Graduations at 90mL and 99mL | Graduations at 90mL and 99mL |
| Accuracy ±4mL | Accuracy ±1mL | Accuracy ±1mL |
| For 1/10 and 1/100 dilutions | For 1/10 and 1/100 dilutions | For 1/10 and 1/100 dilutions |
| Temp range -40oC to 121oC | Temp range -100oC to 165oC | Temp range -100oC to 165oC |
| Autoclavable | Autoclavable | Autoclavable |
| Complies with Part 21 CFR 177.1520 for food use | Complies with Part 21 CFR 177.1655 for food use | Complies with Part 21 CFR 177.1655 for food use |
| BPA-Free | contains BPA | contains BPA |
| Phthalate-free | Phthalate-free | Phthalate-free |
General chemical compatibility
| Wide-Mouth PPCO Dilution Bottle | Wide-Mouth PSF Dilution Bottle | Narrow-Mouth PSF Dilution Bottle | |
| Acids, dilute or weak | E | E | E |
| Acids^ strong, concentrated | G | G | G |
| Alcohols, aliphatic | E | G | G |
| Aldehydes | G | F | F |
| Bases/alkali | E | E | E |
| Esters | G | N | N |
| Hydrocarbons, aliphatic | G | G | G |
| Hydrocarbons, aromatic | N | N | N |
| Hydrocarbons, halogenated | N | N | N |
| Ketones, aromatic | N | N | N |
| Oxidizing agents, strong | F | G | G |
For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.
| E | No damage after 30 days constant exposure at 20oC |
| G | Little or no damage after 30 days constant exposure at 20oC |
| F | Some effect after 7 days constant exposure at 20oC |
| N | Not recommended. Immediate damage may occur. |
^Except for oxidizing acids, see "Oxidizing acids, strong."
| Narrow-Mouth Square PPCO Bottle (2016-series) | Narrow-Mouth Square HDPE Bottles (2018-series) | Narrow-Mouth Square PC Bottle (2015-series) | Narrow-Mouth Square PETG Bottle (2019-series) |
| Good chemical resistance, graduated, autoclavable | Good chemical resistance, graduated | Window clear, superior impact resistance, graduated, autoclavable | Window clear, graduated, sterile |
| | | |
| PPCO bottle PP Closure | HDPE bottle PP Closure | PC bottle PP closure | PETG bottle HDPE Closure |
| Milky white translucent | Milky white translucent | Window clear | Window clear |
| 30mL–1L | 30mL–1L | 30mL–2L | 30mL–2L |
| Leakproof* | Leakproof* | Leakproof* | Leakproof* |
| Molded graduations | Molded graduations | Molded graduations | Molded graduations |
| Temp range -40oC to 121oC | Temp range -100oC to 120oC | Temp range -135oC to 135oC | Temp range -40oC to 70oC |
| Autoclavable | Not autoclavable | Autoclavable | Not autoclavable |
| Complies with Part 21 CFR 177.1520 for food use | Complies with Part 21 CFR 177.1520 for food use1 | Complies with Part 21 CFR 177.1580 for food use | Complies with Part 21 CFR 177.1315 for food use2 |
| BPA-Free | BPA-Free | contains BPA | BPA-Free |
| Phthalate-free | Phthalate-free | Phthalate-free | Phthalate-free |
General Chemical Compatibility
| Narrow-Mouth Square Lab Quality Bottle (2016-series) | Narrow-Mouth Square HDPE Bottles (2018-series) | Narrow-Mouth Square Bottle (2015-series) | Narrow-Mouth Square Bottle (2019-series) | |
| Acids, dilute or weak | E | E | E | G |
| Acids^ strong, concentrated | G | G | N | N |
| Alcohols, aliphatic | E | E | G | G |
| Aldehydes | G | G | F | G |
| Bases/alkali | E | E | N | N |
| Esters | G | G | N | F |
| Hydrocarbons, aliphatic | G | G | G | G |
| Hydrocarbons, aromatic | N | N | N | N |
| Hydrocarbons, halogenated | N | N | N | N |
| Ketones, aromatic | N | N | N | N |
| Oxidizing agents, strong | F | F | F | F |
For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.
| E | No damage after 30 days constant exposure at 20oC. |
| G | Little or no damage after 30 days constant exposure at 20oC. |
| F | Some effect after 7 days constant exposure at 20oC. |
| N | Not recommended. Immediate damage may occur. |
Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)
2. PETG is acceptable for alcoholic foods containing not more than 15% by volume alcohol; fill and storage temperature not to exceed 49oC(120oF). Nonalcoholic foods of hot fill not to exceed 82oC(180F) and 49oC(120F) in storage. Not suitable for carbonated beverages or beer or packaging food requiring thermal processing.
*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except for oxidizing acids, see "Oxidizing acids, strong."
| Wide-Mouth Square High Density HDPE Bottles (2114-series) | Wide-Mouth Square PPCO Bottle (2110-series) | Large Wide-Mouth Square HDPE Bottle (2123-series) | Large Wide-Mouth Square PPCO Bottle (2122-series) |
| Space-saving square shape, wide mouth | Space-saving square shape, wide mouth, autoclavable | Large capacity, molded hand grip | Large capacity, molded hand grip, autoclavable |
| | | |
| HDPE bottle PP Closure | PPCO bottle PP closure | HDPE bottle white PP Closure | PPCO bottle white PP Closure |
| Milky white translucent | Milky white translucent | Milky white translucent | Milky white translucent |
| 60mL–1L | 60mL–1L | 4L | 4L |
| Leakproof* | Leakproof* | Not liquid leakproof | Not liquid leakproof |
| No graduations | No graduations | No graduations | No graduations |
| Temp range -100oC to 120oC | Temp range -40oC to 121oC | Temp range -100oC to 120oC | Temp range -40oC to 121oC |
| Not autoclavable | Autoclavable | Not autoclavable | Autoclavable |
| Complies with Part 21 CFR 177.1520 for food use1 | Complies with Part 21 CFR 177.1520 for food use | Complies with Part 21 CFR 177.1520 for food use1 | Complies with Part 21 CFR 177.1580 for food use |
| BPA-Free | BPA-Free | BPA-Free | BPA-free |
| Phthalate-free | Phthalate-free | Phthalate-free | Phthalate-free |
General chemical compatibility
| Wide-Mouth Square HDPE Bottles (2114-series) | Wide-Mouth Square Lab Quality Bottle (2110-series) | Large Wide-Mouth Square HDPE Bottle (2123-series) | Large Wide-Mouth Square Bottle (2122-series) | |
| Acids, dilute or weak | E | E | E | E |
| Acids^ strong, concentrated | G | G | G | G |
| Alcohols, aliphatic | E | E | E | E |
| Aldehydes | G | G | G | G |
| Bases/alkali | E | E | E | E |
| Esters | G | G | G | G |
| Hydrocarbons, aliphatic | G | G | G | G |
| Hydrocarbons, aromatic | N | N | N | N |
| Hydrocarbons, halogenated | N | N | N | N |
| Ketones, aromatic | N | N | N | N |
| Oxidizing agents, strong | F | F | F | F |
For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.
| E | No damage after 30 days constant exposure at 20 oC |
| G | Little or no damage after 30 days constant exposure at 20oC |
| F | Some effect after 7 days constant exposure at 20oC |
| N | No recommended. Immediate damage may occur |
Footnote:
1. HDPE and LDPE are acceptable for: Nonacid, aqueous products; may contain salt, sugar or both (pH above 5.0). Dairy products and modifications; oil-in-water emulsions, high or low fat. Moist bakery products with surface containing no free fat or oil. Dry solids with the surfaces containing no free fat or oil (no end-test required) and under all conditions as described in Table 2 of FDA Regulation 177.1520 except condition A - high temperature sterilization (e.g. over 100° C / 212° F)
*The term “leakproof” applies to Thermo Scientific Nalgene products that meet the following criteria: a) Bottle/flask/funnel closure systems with closures smaller than 100mm, after they are filled with water, inverted, withstand air pressure of 2psig for 2 minutes, and no water escapes;. b) Bottle/funnel/flask closure systems of larger than 100mm after they are filled with water, inverted for 15 minutes, and no water escapes. Note: these tests, using other liquids, may not yield the same results. To ensure safe usage, customers are advised to test Thermo Scientific Nalgene bottles and closures under conditions of their planned applications. Thermo Scientific Nalgene products are leakproof at ambient temperature and pressure when used with their Nalgene closures.
^Except for oxidizing acids, see "Oxidizing acids, strong."
| Wide-Mouth PPCO Dilution Bottle | Wide-Mouth PSF Dilution Bottle | Narrow-Mouth PSF Dilution Bottle |
| Better chemical resistance, less accurate | Better accuracy and clarity, higher temp range | Better accuracy and clarity, higher temp range |
| | |
| PPCO bottle PP Closure | PSF bottle PP Closure | PSF bottle PP closure |
| Milky white translucent | Transparent, yellow tint | Transparent, yellow tint |
| Brim capacity 220mL | Brim capacity 220mL | Brim capacity 210mL |
| Capacity to neck 205mL | Capacity to neck 205mL | Capacity to neck 200mL |
| Cap size 38mm | Cap size 38mm | Cap size 28mm |
| Wide mouth | Wide mouth | Narrow mouth |
| Leakproof* | Leakproof* | Leakproof* |
| Graduations at 90mL and 99mL | Graduations at 90mL and 99mL | Graduations at 90mL and 99mL |
| Accuracy ±4mL | Accuracy ±1mL | Accuracy ±1mL |
| For 1/10 and 1/100 dilutions | For 1/10 and 1/100 dilutions | For 1/10 and 1/100 dilutions |
| Temp range -40oC to 121oC | Temp range -100oC to 165oC | Temp range -100oC to 165oC |
| Autoclavable | Autoclavable | Autoclavable |
| Complies with Part 21 CFR 177.1520 for food use | Complies with Part 21 CFR 177.1655 for food use | Complies with Part 21 CFR 177.1655 for food use |
| BPA-Free | contains BPA | contains BPA |
| Phthalate-free | Phthalate-free | Phthalate-free |
General chemical compatibility
| Wide-Mouth PPCO Dilution Bottle | Wide-Mouth PSF Dilution Bottle | Narrow-Mouth PSF Dilution Bottle | |
| Acids, dilute or weak | E | E | E |
| Acids^ strong, concentrated | G | G | G |
| Alcohols, aliphatic | E | G | G |
| Aldehydes | G | F | F |
| Bases/alkali | E | E | E |
| Esters | G | N | N |
| Hydrocarbons, aliphatic | G | G | G |
| Hydrocarbons, aromatic | N | N | N |
| Hydrocarbons, halogenated | N | N | N |
| Ketones, aromatic | N | N | N |
| Oxidizing agents, strong | F | G | G |
For a more detailed chemical resistance guide by chemical and application temperature, please refer to Chemical resistance guide or request a printed poster for your lab or contact Nalgene Technical Support.
| E | No damage after 30 days constant exposure at 20oC |
| G | Little or no damage after 30 days constant exposure at 20oC |
| F | Some effect after 7 days constant exposure at 20oC |
| N | Not recommended. Immediate damage may occur. |
^Except for oxidizing acids, see "Oxidizing acids, strong."
Technical support
For assistance choosing products appropriate for your application, please speak with a Nalgene Technical Support Representative team by phone at +1.585.586.8800 or (1.800.625.4327 US toll free), or email your request to
technicalsupport@thermofisher.com.
In Austria, France, Germany, Ireland, Switzerland and the United Kingdom please contact technical support by phone at +800 1234 9696 (toll free) or +49.6184.90.6321, or email your request to techsupport.labproducts.eu@thermofisher.com.
Regulatory Support: For regulatory documentation of product or material claims, please contact Nalgene Regulatory Support at RocRegSupport@thermofisher.com
Resources
Related information
- Break the Glass Habit Brochure
- Bottle and Carboy Selection Guide
- Plastic Properties Reference Magnet
- Plastic Labware Chemical Resistance Wall Poster
California Proposition 65 Warning: Products manufactured with polycarbonate (PC), polyethylene terephthalate (PET), polyethylene terephthalate glycol (PETG) or polystyrene (PS) contain chemicals known to the State of California to cause cancer, birth defects or other reproductive harm.