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Acquiring high-quality data doesn’t need to be a challenge
Acquire the highest quality data possible to unlock the information, knowledge, and value in your samples with Thermo Scientific LC-MS Data Acquisition software.
No matter what LC, GC, IC or MS system you are using, or the complexity of the experiment you wish to perform – acquiring your data should be simple. From flexible solutions for research-based applications to routine and compliance-ready solutions or open access needs, we have you covered.
Learn more about LC-MS Data Acquisition software
Being able to set up and control your LC-MS instrumentation, from quadrupole to high-resolution, accurate-mass mass spectrometers (HRAM-MS), should be simple, flexible and ensure that you can acquire the highest quality data possible so you can make confident, informed decisions. Learn more about the options to control your Thermo Scientific mass spectrometers based upon your requirements.
Control, process, and explore your high-quality data acquired from Thermo Scientific LC-MS systems and related instrumentation, including third-party LC inlets. Thermo Scientific Xcalibur software provides complete method setup, data acquisition, processing and reporting capabilities with tools such as Freestyle and Quan Browser, as well as the algorithm AcquireX data acquisition.
Providing access to all of your installed applications from small-molecule, application-specific data processing software such as Thermo Scientific Compound Discoverer software to large molecule Thermo Scientific Proteome Discoverer software, as well as a host of cloud-based applications, never be without the latest tools or update notifications.
Key benefits of Xcalibur software
| All your applications in one place | Comprehensive and instinctive method editing | Easily interrogate your high-quality data | Get the latest updates and information |
|---|---|---|---|
| With a comprehensive portfolio of application-specific packages, access all your installed applications from customizable landing pages, including cloud-based applications. | Acquiring the highest-quality data is critical to ensuring its transformation into actionable knowledge. Powerful method-editing capabilities through drag-and-drop method creation, makes it easy to obtain deep insights into your data. | Whether you want to perform quick quantification of several compounds, or more deeply interrogate your raw data, the latest visualization and analysis tools allow you to see what’s really there. | From new and updated data acquisition methods to installed application updates, you’ll never miss out when new and enabling capabilities are deployed. |
The customizable landing page shows all your available data acquisition, interrogation, and processing tools (note that some applications, such as FreeStyle, are included with Xcalibur software whereas others depend upon your instrumentation or purchased applications). With notifications when the latest data acquisition method templates are available, as well as product updates, you’ll never miss out on being able to acquire and interrogate your data, delivering insights and allowing you to focus on your science.
A consistent, unified architecture between the latest Thermo Scientific Tribrid mass spectrometer, the Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer and Thermo Scientific triple quadrupole mass spectrometers means that users of all experience levels can acquire high-quality data with minimal training. Acquisition methods can be rapidly created with drag-and-drop capabilities, or you can choose from multiple default templates covering the most popular experiments, allowing walk-up access and data acquisition.
Control your laboratory regardless of vendor, with extensible, compliance-ready software covering a broad range of instrumentation as well as multiple Thermo Scientific ion chromatography (IC), liquid chromatography (LC) and gas chromatography (GC) quadrupole and HRAM-MS systems: standalone, over a network or enterprise.
With routine screening and quantitative capabilities to intact mass analysis and multi-attribute method (MAM) as well as regulated bioanalysis, do more with less.
eWorkflow procedures allow you to create complete analyses, from data acquisition to processing and reporting, which means simplified training and system operation, as well as confident and consistent results across your organization.
Key benefits of Chromeleon CDS
| Regulatory compliance for your MS analyses | Multi-instrument control across your enterprise | Productivity and efficiency | Continuous evolution to meet market demands |
|---|---|---|---|
| Requirements for acquiring and processing data under compliant conditions are increasing in many application areas. Thermo Scientific Chromeleon Chromatography Data System (CDS) streamlines multiple MS workflows while keeping up with evolving compliance regulations (e.g., GLP/GMP and 21 CFR part 11 regulations). | Streamlining instrument control within your laboratory, or across multiple laboratories globally has never been easier with reliable control for over 525 different instrument modules from over 20 LC and GC vendors, as well as control of multiple Thermo Scientific triple quadrupole MS and high-resolution MS systems. | Drive productivity through consistent control of multiple laboratory instruments, or provide open access capabilities. From method creation to reporting, these capabilities can be conveniently bundled into an eWorkflow so anyone can access, run, and report your assays. | With the drive to utilize MS within QC and Lot Release for complex Biotherapeutics, the ability to perform peptide mapping (Multi-Attribute Method) and intact mass deconvolution, or regulated bioanalysis further upstream, this trusted CDS environment futureproofs your laboratory. |
With customizable views, it is fast and simple to create MS quantitative analyses. Easy visualization and quantitation of all components is achieved using intelligent MS quan, which automates the processing of all components based upon their quantitation ions. Spectra from chromatographic peaks can be easily displayed and compared, through handy thumbnail spectra, or in more detail in the dedicated plots.
From the multi-attribute method and targeted peptide mapping with new peak detection to intact mass analysis and deconvolution within a compliance-ready environment, Chromeleon CDS provides laboratories wishing to implement HRAM-MS within regulated environments with the necessary tools. Seamless integration with discovery-focused Thermo Scientific BioPharma Finder software enables easy method development and set-up before transfer into Chromeleon CDS. Additionally, Chromeleon CDS interfaces with both Thermo Fisher SampleManager LIMS, the world's most widely deployed LIMS, and Thermo Fisher Watson LIMS for bioanalytical workflow management, as used by the top 20 global pharma and biopharma organizations.
Increase productivity by acquiring and processing your targeted screening and routine quantitative data from Thermo Scientific LC and GC quadrupole and HRAM-MS systems.
With configuration for environmental-, clinical-, food safety-, forensics- and pharma/biopharma-specific nomenclature, you can rapidly and flexibly develop confident routine quantitative or targeted screening workflows that are accessible to all with minimal training requirements.
Offering user log in with controlled privileges, combined with the ability to tailor what you see on-screen, method and reporting templates, and highly visualized data review; Thermo Scientific TraceFinder software allows you to rapidly acquire, process, review and report your high-throughput quantitative or targeted screening workflows with accuracy, precision, and confidence.
Key benefits of TraceFinder software
| Complete configurability | Quantify more, in less time | Access the latest mass spectral library information | Manage your data; don’t let your data manage you |
|---|---|---|---|
In high-throughput laboratories, time spent learning new software means less time for analyzing samples. With market-specific terminology, user login for different operator levels, and configurable views to aid data processing and reporting, spend more time generating results. | Easily configurable methods, and the ability to select pre-configured methods and reporting templates, combined with real-time processing and data evaluation means that your results are rapidly available for review and reporting whether they are from quadrupole or high-resolution data. | Targeted methods can be rapidly populated with target compounds from compound databases. When screening or requiring additional confirmation, or to identify unknowns, you can access the latest Thermo Scientific mzCloud mass spectral library contents through mzVault as well as utilize the NIST mass spectral library. | Your data is your knowledge, so it has inherent value. Being able to acquire and store data across your network means that you can safeguard this knowledge and manage data more easily. |
With targeted screening, confidence in your results is key. The ability for multiple forms of confirmation from spectral library matching, fragment ion confirmation through to isotopic pattern confirmation (as shown above), and highly visual data review capabilities not only affords rapid data review and reporting, but assurance that you have matched your targets.
Simplify review based upon your needs with a data review that is highly visual and flexible based upon sample or compound views, using filters and groups, which can also be carried forwards to reporting.
For assays where exhaustive sample profiling is required to ensure each compound has sufficient, high-quality accurate-mass fragmentation information (MSn) for confident compound identification, AcquireX data acquisition allows you to automate this traditionally tedious process.
Pre-defined method templates are available to use straight away, or to facilitate rapid method development. AcquireX experiments provide you with the means to capture MSn fragmentation spectra on the components of interest, and not background ions or matrix components.
Collect more meaningful data, and not just more data.
Key benefits of AcquireX software
| Collect more meaningful data, not just more data | Fully automated, all-inclusive data acquisition | Increased productivity and more confident identifications |
|---|---|---|
| Typical LC-MSn workflows compromise between spectral quality, specificity, and coverage and require extensive manual input. Break these dependencies and capture high-quality MSn spectral data on every compound in your sample, automatically. | From background exclusion to the inclusion of sample compounds, automated include/exclude list updates and iterative sample re-injections ensure exhaustive MSn profiling without the need for manual interrogation. | Compared to 'traditional' DDA, both the number of compounds with in-depth fragmentation spectra and the confidence in spectral matches increases, when using AcquireX with Thermo Scientific Compound Discoverer software or Thermo Scientific Mass Frontier software with mzCloud is increased. |
Through analysis of sample background (a blank), an exclusion list is automatically created, followed by a full scan MS analysis to create an inclusion list of precursor ions. These inclusion and exclusion lists are then used to dynamically analyze your sample.
The lists are automatically updated as MSn data is acquired for each compound, ensuring data quality through reduced redundancy in the total number of fragmentation spectra per compound.
Learn more about LC-MS Data Acquisition software
You can use the instrument control software to collect high-quality mass spectrometry data on the Thermo Scientific mass spectrometers. Control of the instruments is through two application packages: Tune and Method Editor.
For questions about the software, to request features, or to report defects, send an email by clicking here.
Orbitrap Astral MS series instrument control software version 1.1
Release date | Build number | Instruments | Software requirements |
|---|---|---|---|
| September 18, 2024 | 1.1.477.46 | Orbitrap Astral MS | Microsoft™ Windows™ 10 Enterprise 2021 LTSC Thermo Scientific Xcalibur 4.7 |
New features |
|---|
| Stepped Collision Energy: The user needs the ability to perform the acquisition of single MS2 scan with multiple Collision Energy values when using Astral detector Type |
| Full Profile: The user needs the ability to perform Orbitrap MS1 and MS2 acquisition with Full Profile in Intact Protein Mode |
| NSI: The user needs an updated default value of Positive Spray Voltage for NSI in ME and Tune |
| Orbitrap Astral shall automatically correct the ion foil voltage using the ICS |
| FAIMS CV switching performance shall be improved |
| The user needs the "Lock mass injection" to be a parameter in the scan properties for each scan type |
| Method Editor: The System Templates must be saved in "Astral" folder |
| The user needs the possibility to choose "Use EASY-IC" On/Off for each experiment/scan type in Timed Mode |
| The user needs to be able to see the displayed absolute AGC target values |
| Tune: Favorites/User Settings and History information must be saved in "Astral" folders |
| The user needs the ability to monitor pressure readbacks for Astral Analyzer in Tune |
Known issues |
| See Orbitrap Astral MS series ICSW v.1.1 Release notes › |
Fixed detects in Orbitrap Astral MS series instrument control software version 1.1 |
| MongoDB uses large memory (>3GB) at background |
| If in DIA experiments (using Astral detector) a Loop Time is defined, as shorter than the Orbitrap transient time set in another experiment of the method, the instrument schedules not enough DIA scans to match the expected loop control time |
| Fluxscans are not used in edge cases (first mass/last mass +/- isolation width) |
| DIA: Methods miswriting mass window centers as 524.265 in raw file instrument method |
| Missing Plot: Mass Calibration |
| Tune: Pressure Mode always set to Standard Pressure after startup |
| Tune UI: Astral Turbo pumps readbacks are swapped |
| Issue with DIA Windows Definition with Windows Optimization "On" under certain conditions |
| Max IT information is not copied when using copy/paste functionality of MS2 information - instead default max IT (10 ms) is used |
| "Use EASY-IC" dropdown is not available if Lock Mass correction mode is set to "timed" |
| Instrument reported to be set to standby because of open source, but continued the sequence |
| The search window for the EASY-IC lockmass is shifted by outliers |
| "Bakeout cooling time" and other ICB/HICB timers are reset by software update |
| Astral Mass Stabilization is performed at different timepoints within a LC-MS run |
| Syringe does not get turned off during Electronics Smart Calibration in User System Calibration |
| Setting the Funnel RF Level to default is not in Astral Default Scan Settings |
| For more info refer to Orbitrap Astral MS series ICSW v.1.1 Release notes › |
Contact us |
| Orbitrap Astral MS series request Orbitrap Astral MS series issue |
Orbitrap Tribrid MS series instrument control software version 4.2 QF1
Release date | Build number | Instruments | Software requirements |
|---|---|---|---|
| July 30, 2024 | 4.2.4321.0 | Orbitrap Ascend MS, Orbitrap Eclipse MS, Orbitrap Fusion Lumos, Orbitrap Fusion MS, Orbitrap IQ-X MS, Orbitrap ID-X | Microsoft™ Windows™ 10 Enterprise 2019 LTSC Thermo Scientific Xcalibur 4.7 or later |
New features |
|---|
| Hardware Support (Orbitrap Ascend Editions only) |
| High-Quad, for controlled isolation up to 8000 m/z |
| High mass calibration support (High-Quad only) |
| Quadrupole frequency switching support (High-Quad only) |
| Tune Alert Window |
| Enhanced Unclog routine to unclog Autoready source emitter |
| Fragment Ion Indexing for RTLS |
| Extended Enzyme list for RTS searches |
| Exclude Isotopes for Targeted Mass Exclusion and Targeted Loss Exclusion filters |
| Enhanced Input for HCD scan types in Tune. Input field now accepts 1–5 values to control single or stepped collision energy mode |
| Support for TMT 32plex |
| Resolving power options for Orbitrap Scans 90000 & 75000 (not for IDX/IQX) |
| Support for Chromeleon™ software. The Chromeleon driver compatibility matrix reflects the tested compatibility for combinations of Orbitrap Tribrid Series instrument control software versions, Chromeleon software versions, and instrument models. For more information and to view the compatibility matrix, sign on to https://support.thermoinformatics.com/downloads/default.aspx, and then select Chromeleon > Chromeleon > Related Drivers > Driver Compatibility Matrix. |
Usability enhancements:
|
Known issues |
| See Orbitrap Tribrid MS Series ICSW v4.2 QF1 Release notes |
Fixed defects |
| See Orbitrap Tribrid MS series ICSW 4.2 QF1 Release notes |
Contact us |
| Orbitrap Tribrid series request Orbitrap Tribrid series issue |
Orbitrap Exploris MS series instrument control software version 4.3
Release date | Build number | Instruments | Software requirements |
|---|---|---|---|
| March 28, 2024 | 4.3.458.14 | Orbitrap Exploris 480 MS, Orbitrap Exploris 240 MS, Orbitrap Exploris 120 MS, Orbitrap Exploris MX MS, Orbitrap Exploris GC MS, and Orbitrap Exploris GC 240 MS | Microsoft™ Windows™ 10 Enterprise 2016 LTSB, 2019 LTSC or 2021 LTSC Thermo Scientific Xcalibur 4.7 |
New features |
|---|
| Exploris GC: User-defined Lock Mass Correction Mode “RunStart” at the beginning of the data acquisition. |
| Method Editor - Scan Properties: “Custom AGC Targets” display “Absolute AGC Values”. |
| Method Execution: extended the Maximum Injection Time Mode “Dynamic” to ddMS2 Scans. |
| Tune and Method Editor OT Exploris 120 and MX: added Resolution settings 22500, 45000, 90000. |
| Method Editor - Scan Properties: “Use EASY-IC” is extended to Lock Mass Correction Mode “Timed”. |
| Exploris GC: Method Editor - Scan Properties: Product Ion Scan provides Product Ion Window Modes “Center Mass” and “m/z Range”. |
| Exploris GC: Tune - Calibration: Manual Calibration table is separated by polarities. |
| Exploris GC: Tune - Optimization: Leak Check has improved scan settings to eliminate m/z 42. |
| Method Editor - Global MS Settings: “User-defined Lock Mass Injection” transitions to a Scan Property. |
| Method Editor - Global MS Settings: Renamed “Internal Mass Calibration” to “Lock Mass Correction”. |
| Method Execution: Instrument preserves the ion source properties defined in the instrument method after method execution has finished. |
| OT Exploris 240: ddMS2/tMS2 scans allow for broader isolation windows up to 2000 m/z. |
| OT Exploris MX: Tune Diagnostics - Define Scan functions are extended to Orbitrap Exploris MX to access all MALDI related functionalities. |
| Tune - Alert Window emits a warning when starting Calibration/Check procedures while syringe pump is off. |
| Tune Diagnostics - Tools allow for setting a PrOSA Limit value to exclude extreme PrOSA Scaling factors. |
| Tune Preferences: Hotlink function is now limited to the Ion Source properties. |
| Tune Preferences: The One-Point-Self-Calibration options are extended by a Calendar View. |
| Tune: System Calibration stores all calibration values before the ICS Calibration, independent from the ICS HV Calibration outcome. |
Known issues |
| Please refer to Release notes › |
Fixed defects |
| For full list please refer to Release notes › |
Contact us |
| Orbitrap Exploris MS series request Orbitrap Exploris MS series issue |
Exactive MS series instrument control software version 2.13
Release date | Instruments | Software requirements |
|---|---|---|
| June 18, 2024 | Exactive GC MS, Exactive Plus MS, Exactive Plus EMR MS, Q Exactive MS, Q Exactive Focus MS, Q Exactive GC MS, Q Exactive HF MS, Q Exactive HF-X MS, Q Exactive Plus MS, and Q Exactive UHMR MS | Microsoft™ Windows™ 10 Enterprise 2016 LTSB, 2019 LTSC, or 2021 LTSC Thermo Scientific Xcalibur 7 |
New features |
|---|
| Q Exactive UHMR supports Charge Detection MS mode powered by Direct Mass Technology |
Known issues |
| See Exactive Series ICSW v2.13 SP1 Release notes › |
Fixed defects |
| See Exactive Series ICSW v2.13 SP1 Release notes › |
Contact us |
| Exactive MS series request Exactive MS series issue |
Stellar MS instrument control software version 1.0 QF1
Release date | Build number | Instruments | Software requirements |
|---|---|---|---|
| October 9, 2024 | 1.0.4354 | Stellar MS | Min req - Microsoft™ Windows™ 10 Enterprise LTSC 2019 Foundation 3.1 SP9 Xcalibur™ 4.7 |
New features |
|---|
| See Stellar MS ICSW v. 1.0 QF1 Release notes › |
Known issues |
| See Stellar MS ICSW v. 1.0 QF1 Release notes › |
Contact us |
| Stellar MS request Stellar MS issue |
Orbitrap Astral MS series instrument control software version 1.1
Release date | Build number | Instruments | Software requirements |
|---|---|---|---|
| September 18, 2024 | 1.1.477.46 | Orbitrap Astral MS | Microsoft™ Windows™ 10 Enterprise 2021 LTSC Thermo Scientific Xcalibur 4.7 |
New features |
|---|
| Stepped Collision Energy: The user needs the ability to perform the acquisition of single MS2 scan with multiple Collision Energy values when using Astral detector Type |
| Full Profile: The user needs the ability to perform Orbitrap MS1 and MS2 acquisition with Full Profile in Intact Protein Mode |
| NSI: The user needs an updated default value of Positive Spray Voltage for NSI in ME and Tune |
| Orbitrap Astral shall automatically correct the ion foil voltage using the ICS |
| FAIMS CV switching performance shall be improved |
| The user needs the "Lock mass injection" to be a parameter in the scan properties for each scan type |
| Method Editor: The System Templates must be saved in "Astral" folder |
| The user needs the possibility to choose "Use EASY-IC" On/Off for each experiment/scan type in Timed Mode |
| The user needs to be able to see the displayed absolute AGC target values |
| Tune: Favorites/User Settings and History information must be saved in "Astral" folders |
| The user needs the ability to monitor pressure readbacks for Astral Analyzer in Tune |
Known issues |
| See Orbitrap Astral MS series ICSW v.1.1 Release notes › |
Fixed detects in Orbitrap Astral MS series instrument control software version 1.1 |
| MongoDB uses large memory (>3GB) at background |
| If in DIA experiments (using Astral detector) a Loop Time is defined, as shorter than the Orbitrap transient time set in another experiment of the method, the instrument schedules not enough DIA scans to match the expected loop control time |
| Fluxscans are not used in edge cases (first mass/last mass +/- isolation width) |
| DIA: Methods miswriting mass window centers as 524.265 in raw file instrument method |
| Missing Plot: Mass Calibration |
| Tune: Pressure Mode always set to Standard Pressure after startup |
| Tune UI: Astral Turbo pumps readbacks are swapped |
| Issue with DIA Windows Definition with Windows Optimization "On" under certain conditions |
| Max IT information is not copied when using copy/paste functionality of MS2 information - instead default max IT (10 ms) is used |
| "Use EASY-IC" dropdown is not available if Lock Mass correction mode is set to "timed" |
| Instrument reported to be set to standby because of open source, but continued the sequence |
| The search window for the EASY-IC lockmass is shifted by outliers |
| "Bakeout cooling time" and other ICB/HICB timers are reset by software update |
| Astral Mass Stabilization is performed at different timepoints within a LC-MS run |
| Syringe does not get turned off during Electronics Smart Calibration in User System Calibration |
| Setting the Funnel RF Level to default is not in Astral Default Scan Settings |
| For more info refer to Orbitrap Astral MS series ICSW v.1.1 Release notes › |
Contact us |
| Orbitrap Astral MS series request Orbitrap Astral MS series issue |
Orbitrap Tribrid MS series instrument control software version 4.2 QF1
Release date | Build number | Instruments | Software requirements |
|---|---|---|---|
| July 30, 2024 | 4.2.4321.0 | Orbitrap Ascend MS, Orbitrap Eclipse MS, Orbitrap Fusion Lumos, Orbitrap Fusion MS, Orbitrap IQ-X MS, Orbitrap ID-X | Microsoft™ Windows™ 10 Enterprise 2019 LTSC Thermo Scientific Xcalibur 4.7 or later |
New features |
|---|
| Hardware Support (Orbitrap Ascend Editions only) |
| High-Quad, for controlled isolation up to 8000 m/z |
| High mass calibration support (High-Quad only) |
| Quadrupole frequency switching support (High-Quad only) |
| Tune Alert Window |
| Enhanced Unclog routine to unclog Autoready source emitter |
| Fragment Ion Indexing for RTLS |
| Extended Enzyme list for RTS searches |
| Exclude Isotopes for Targeted Mass Exclusion and Targeted Loss Exclusion filters |
| Enhanced Input for HCD scan types in Tune. Input field now accepts 1–5 values to control single or stepped collision energy mode |
| Support for TMT 32plex |
| Resolving power options for Orbitrap Scans 90000 & 75000 (not for IDX/IQX) |
| Support for Chromeleon™ software. The Chromeleon driver compatibility matrix reflects the tested compatibility for combinations of Orbitrap Tribrid Series instrument control software versions, Chromeleon software versions, and instrument models. For more information and to view the compatibility matrix, sign on to https://support.thermoinformatics.com/downloads/default.aspx, and then select Chromeleon > Chromeleon > Related Drivers > Driver Compatibility Matrix. |
Usability enhancements:
|
Known issues |
| See Orbitrap Tribrid MS Series ICSW v4.2 QF1 Release notes |
Fixed defects |
| See Orbitrap Tribrid MS series ICSW 4.2 QF1 Release notes |
Contact us |
| Orbitrap Tribrid series request Orbitrap Tribrid series issue |
Orbitrap Exploris MS series instrument control software version 4.3
Release date | Build number | Instruments | Software requirements |
|---|---|---|---|
| March 28, 2024 | 4.3.458.14 | Orbitrap Exploris 480 MS, Orbitrap Exploris 240 MS, Orbitrap Exploris 120 MS, Orbitrap Exploris MX MS, Orbitrap Exploris GC MS, and Orbitrap Exploris GC 240 MS | Microsoft™ Windows™ 10 Enterprise 2016 LTSB, 2019 LTSC or 2021 LTSC Thermo Scientific Xcalibur 4.7 |
New features |
|---|
| Exploris GC: User-defined Lock Mass Correction Mode “RunStart” at the beginning of the data acquisition. |
| Method Editor - Scan Properties: “Custom AGC Targets” display “Absolute AGC Values”. |
| Method Execution: extended the Maximum Injection Time Mode “Dynamic” to ddMS2 Scans. |
| Tune and Method Editor OT Exploris 120 and MX: added Resolution settings 22500, 45000, 90000. |
| Method Editor - Scan Properties: “Use EASY-IC” is extended to Lock Mass Correction Mode “Timed”. |
| Exploris GC: Method Editor - Scan Properties: Product Ion Scan provides Product Ion Window Modes “Center Mass” and “m/z Range”. |
| Exploris GC: Tune - Calibration: Manual Calibration table is separated by polarities. |
| Exploris GC: Tune - Optimization: Leak Check has improved scan settings to eliminate m/z 42. |
| Method Editor - Global MS Settings: “User-defined Lock Mass Injection” transitions to a Scan Property. |
| Method Editor - Global MS Settings: Renamed “Internal Mass Calibration” to “Lock Mass Correction”. |
| Method Execution: Instrument preserves the ion source properties defined in the instrument method after method execution has finished. |
| OT Exploris 240: ddMS2/tMS2 scans allow for broader isolation windows up to 2000 m/z. |
| OT Exploris MX: Tune Diagnostics - Define Scan functions are extended to Orbitrap Exploris MX to access all MALDI related functionalities. |
| Tune - Alert Window emits a warning when starting Calibration/Check procedures while syringe pump is off. |
| Tune Diagnostics - Tools allow for setting a PrOSA Limit value to exclude extreme PrOSA Scaling factors. |
| Tune Preferences: Hotlink function is now limited to the Ion Source properties. |
| Tune Preferences: The One-Point-Self-Calibration options are extended by a Calendar View. |
| Tune: System Calibration stores all calibration values before the ICS Calibration, independent from the ICS HV Calibration outcome. |
Known issues |
| Please refer to Release notes › |
Fixed defects |
| For full list please refer to Release notes › |
Contact us |
| Orbitrap Exploris MS series request Orbitrap Exploris MS series issue |
Exactive MS series instrument control software version 2.13
Release date | Instruments | Software requirements |
|---|---|---|
| June 18, 2024 | Exactive GC MS, Exactive Plus MS, Exactive Plus EMR MS, Q Exactive MS, Q Exactive Focus MS, Q Exactive GC MS, Q Exactive HF MS, Q Exactive HF-X MS, Q Exactive Plus MS, and Q Exactive UHMR MS | Microsoft™ Windows™ 10 Enterprise 2016 LTSB, 2019 LTSC, or 2021 LTSC Thermo Scientific Xcalibur 7 |
New features |
|---|
| Q Exactive UHMR supports Charge Detection MS mode powered by Direct Mass Technology |
Known issues |
| See Exactive Series ICSW v2.13 SP1 Release notes › |
Fixed defects |
| See Exactive Series ICSW v2.13 SP1 Release notes › |
Contact us |
| Exactive MS series request Exactive MS series issue |
Stellar MS instrument control software version 1.0 QF1
Release date | Build number | Instruments | Software requirements |
|---|---|---|---|
| October 9, 2024 | 1.0.4354 | Stellar MS | Min req - Microsoft™ Windows™ 10 Enterprise LTSC 2019 Foundation 3.1 SP9 Xcalibur™ 4.7 |
New features |
|---|
| See Stellar MS ICSW v. 1.0 QF1 Release notes › |
Known issues |
| See Stellar MS ICSW v. 1.0 QF1 Release notes › |
Contact us |
| Stellar MS request Stellar MS issue |
