Twin-screw extrusion is a standard technique for polymer mixing and compounding, but has also expanded into other applications, such as novel materials development. Extruders offer a high level of process flexibility, control of process parameters, and can produce a wide range of products. Being a continuous mixing process, where a base matrix and multiple additives are transformed into a new compound, twin-screw extrusion has the potential to benefit multiple areas beyond traditional polymer processing.
Thermo Scientific extruders and compounders are designed to offer flexibility, efficiency, and reliable scale-up for a wide range of process requirements.
Lab-scale extruders only require a small amount of material to conduct experiments, allowing you to perform numerous trials efficiently and cost effectively, while also saving precious laboratory space.
With a Thermo Scientific lab-scale twin-screw extruder, easy upscaling from 11, to 16, to 24 mm screw diameters is ensured by design.
Comprehensive characterization is often essential during the development of new, innovative materials. Thermo Scientific HAAKE PolyLab Torque Rheometers are measuring mixer and extruder systems designed to meet today’s (and tomorrow’s) quality control and R&D needs. This modular system starts with a torque rheometer drive that can be connected to an interchangeable mixer, single-screw extruder, or conical/parallel twin-screw extruders. Analyze material properties, simulate production processes, and perform capillary rheology to determine flow characteristics under real process conditions.
When developing new drugs, shorter time-to-market, reduced waste of expensive APIs, and minimized development costs provide a distinct competitive advantage for pharmaceutical manufacturers. Thermo Scientific pharmaceutical extruders and related analytical instrumentation shorten the path from feasibility studies to manufacturing and help overcome drug formulation challenges.
The Thermo Scientific Process Control Rheometer Series (PCR) is ideal for continuous, real-time measurement of viscosity and melt flow index, ensuring high quality during the production or recycling of polymers and other related materials.
Thermo Scientific micro-compounders are conical twin-screw extruders, well-suited for polymer, pharmaceutical, bioscience, and nanotechnology R&D. All models use as little as five grams (or seven milliliters) of material for compounding. This is especially beneficial if you compound expensive or small-scale materials. The optional force-feeder attachment even allows you to continuously extrude very small material volumes.
Barrel diameter (mm) | Barrel length L/D |
Da/Di | Achievable output (kg/h)* |
Temp. (°C) | Screw design | Max. screw speed (rpm) | Temp. zones ** | Drive power (kW) | |
HAAKE MiniCTW | Conical | 0.01–0.1 | 300 | Conical co- and counter rotating | 360 | 2*** | 0.4 | ||
Pharma mini HME | Conical | 0.01–0.1 | 280 | Conical co- and counter rotating | 360 | 2*** | 0.4 | ||
MiniLab 3 | Conical | 0.01–0.1 | 350 (420) | Conical co- and counter rotating | 360 | 2*** | 0.4 | ||
Laboratory scale | |||||||||
Pharma 11 | 11 | 40 | 1.72 | 0.02–2.5 | 280 | Parallel co-rotating | 1000 | 8 | 1.5 |
Process 11 | 11 | 40 | 1.72 | 0.02–2.5 | 350 (450) | Parallel co-rotating | 1000 | 8 | 1.5 |
Process 16 | 16 | 40 | 1.73 | 0.4–20 | 350 (450) | Parallel co-rotating | 1000 | 8 | 3.7 |
Rheomex PTW 16 OS | 16 | 25 (40) | 1.73 | 0.2–10 | 400 (450) | Parallel co-rotating | 1100 | 7 (10) | 7 (16)**** |
Rheomex PTW 24 OS | 24 | 28 (40) | 1.77 | 0.5–50 | 400 (450) | Parallel co-rotating | 1100 (560) | 7 (10) | 16 (7)**** |
Rheomex CTW 100 OS | Conical | 0.2–5 | 450 | Conical counter rotating | 250 | 3 | 7 (16)**** | ||
Pilot processing and production | |||||||||
TSE 24 MC | 24 | 28 (40) | 1.77 | 0.5–50 | 400 (450) | Parallel co-rotating | 500 (1000) | 7 (10) | 5.5(11) |
Pharma 16 | 16 | 40 | 1.73 | 0.2–5 | 300 | Parallel co-rotating | 1000 | 8 | 2.5 |
Pharma 24 | 24 | 40 | 1.77 | 0.5–20 | 300 | Parallel co-rotating | 1000 | 8 | 11 |
L/D = Ratio of flighted screw length to outer diameter
PC = External computer control
TS = Integrated touchscreen control
* = Material dependent
** = Barrel length dependent
*** = Common set point
****= Driven by PolyLab drive unit
( ) = Optional
For Research Use Only. Not for use in diagnostic procedures.