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| Mandi CS, et al. (2022) Cleavage of Abasic Sites in DNA by an Aminoquinoxaline Compound: Augmented Cytotoxicity and DNA Damage in Combination with an Anticancer Drug Chlorambucil in Human Colorectal Carcinoma Cells. ACS Omega Feb 18 doi: 10.1021/acsomega.1c04962. | 2022 | Cancer studies | Colorectal cancer |
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| Liu M, et al. (2022) miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1. Cardiol Res Pract Feb 17 doi: 10.1155/2022/7687154 | 2022 | Other | |
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2022 |
Cell signaling |
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| Choi YH , et al. (2022) Antiandrogenic activity of Riboflavin 5′-phosphate (FMN) in 22Rv1 and LNCaP human prostate cancer cell lines. Eur J Pharmacol Jan 5 doi: 10.1016/j.ejphar.2022.174743. |
2022 |
Cancer studies |
General |
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2022 |
Other |
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2022 |
Other |
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2022 |
Cancer studies |
Squamous cell carcinoma |
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2022 |
Plant sciences |
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2022 |
Structural biology/protein interactions |
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2022 |
Mitochondrial studies |
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2022 |
Microorganisms and model organisms |
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| Yin J, et al. (2022) Development of a whole-cell biosensor for detection of antibiotics targeting bacterial cell envelope in Bacillus subtilis. Appl Microbiol Biotechnol 106(2):789-798. |
2022 |
Microorganisms and model organisms |
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2022 |
Cancer studies |
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2021 |
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2021 |
Other |
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2021 |
Cancer studies |
Gastric cancer |
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2021 |
Other |
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2021 |
Neurobiology |
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| An X, et al. (2021) Discovery of a widespread presence bunyavirus that may have symbiont‐like relationships with different species of aphids. Insect Sci Dec 7 doi: 10.1111/1744-7917.12989. |
2021 |
Microorganisms and model organisms |
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2021 |
Neurobiology |
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| Avila H, et al. (2021) Intracellular Dynamin Elastin-like Polypeptides Assemble into Rodlike, Spherical, and Reticular Dynasomes. Biomacromolecules Dec 16 doi: 10.1021/acs.biomac.1c01251. |
2021 |
Structural biology/protein interactions |
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| Bade AN, et al. (2021) Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment. Mol Neurobiol Aug 14 doi: 10.1007/s12035-021-02508-5. |
2021 |
Neurobiology |
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2021 |
Cancer studies |
Breast cancer |
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2021 |
Neurobiology |
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2021 |
Other |
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2021 |
Cancer studies |
Pancreatic cancer |
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2021 |
Cancer studies |
General |
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2021 |
Cell signaling |
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| Burgess HM, et al. (2021) Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication. Genes Dev 35(13-14):1005-1019. |
2021 |
Microorganisms and model organisms |
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| Burr SD, et al. (2021) Rap1a Regulates Cardiac Fibroblast Contraction of 3D Diabetic Collagen Matrices by Increased Activation of the AGE/RAGE Cascade. Cells 10(6) 1286 |
2021 |
Cell signaling |
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2021 |
Cancer studies |
Lung cancer |
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2021 |
Stem cells |
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| Carinci M, et al. (2021) TFG binds LC3C to regulate ULK1 localization and autophagosome formation. EMBO J May 1 doi: 10.15252/embj.2019103563 |
2021 |
Cell signaling |
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2021 |
Other |
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2021 |
Other |
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| Chang H, et al. (2021) PARP1 Is Targeted by miR-519a-3p and Promotes the Migration, Invasion, and Tube Formation of Ovarian Cancer Cells. Cancer Biother Radiopharm May 18 doi: 10.1089/cbr.2020.4394 |
2021 |
Cancer studies |
Ovarian cancer |
| Chen F, et al. (2021) Prognostic plasma exosomal microRNA biomarkers in patients with substance use disorders presenting comorbid with anxiety and depression. Sci Rep 11(1):6271. |
2021 |
Disease study: biomarker research |
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| Chen L, et al. (2021) Downregulation of GTSE1 leads to the inhibition of proliferation, migration, and Warburg effect in cervical cancer by blocking LHDA expression. J Obstet Gynaecol Res Sep 5 doi: 10.1111/jog.15000. |
2021 |
Cancer studies |
General |
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2021 |
Cancer studies |
Liver cancer |
| Cheng TY, et al. (2021) β-(1→ 4) Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex. Cells Jul 5 doi: 10.3390/cells10071774. |
2021 |
Neurobiology |
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| Cherngwelling R, et al. (2021) Agomelatine protects against obesity-induced renal injury by inhibiting endoplasmic reticulum stress/apoptosis pathway in rats. Toxicol Appl Pharmacol 425:115601. |
2021 |
Cell signaling |
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2021 |
Other |
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2021 |
Neurobiology |
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| Contreras L, et al. (2021) Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms. Pharmacol Rep Aug 26 doi: 10.1007/s43440-021-00322-3. |
2021 |
Cancer studies |
General |
| D'Acunzo, P, et al, (2021) Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome. Sci Adv 7(7):eabe5085. |
2021 |
Neurobiology |
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| Dai C, et al. (2021) A non‐translational role of threonyl‐tRNA synthetase in regulating JNK signaling during myogenic differentiation. FASEB J 35(10):e21948. |
2021 |
Cell signaling |
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| Danac JMC, et al. (2021) CircPVT1 attenuates negative regulation of NRAS by let-7 and drives cancer cells towards oncogenicity. Sci Rep 11(1):9021 |
2021 |
Cancer studies |
Other |
| Daruich A, et al. (2021) Oral Ursodeoxycholic Acid Crosses the Blood Retinal Barrier in Patients with Retinal Detachment and Protects Against Retinal Degeneration in an Ex Vivo Model. Neurotherapeutics Feb 3 doi: 10.1007/s13311-021-01009-6. |
2021 |
Drug mechanism |
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| Das P, et al. (2021) Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression. J Biol Chem Sep 14 doi: 10.1016/j.jbc.2021.101198. |
2021 |
Microorganisms and model organisms |
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| Delgado-Peraza F, et al. (2021) Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease. Cells 10(5):993 |
2021 |
Neurobiology |
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| Demonbreun AR, et al. (2021) Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy. Sci Transl Med 13(610):eabf0376. |
2021 |
Drug mechanism |
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| Di Filippo M, et al. (2021) Interleukin-17 affects synaptic plasticity and cognition in an experimental model of multiple sclerosis. Cell Rep 37(10):110094. |
2021 |
Neurobiology |
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| Diller T, et al. (2021) Biological Validation of a Novel Process and Product for Quantitating Western Blots. J Biotechnol 326: 52–60. |
2021 |
Method development |
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| Dong P, et al. (2021) Runjing Decoction alleviated cyclophosphamide‐induced oligoasthenospermia rats by inhibiting cell apoptosis via RXFP1/AKT/FOXO1 pathway. Andrologia Aug 16 doi: 10.1111/and.14216 |
2021 |
Cell signaling |
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| Douglass M, et al. (2021) EXPRESS: L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells. Pulm Circ Mar 16 doi: 10.1177/20458940211006289. |
2021 |
Other |
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| Dupont L, et al. (2021) The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr. Cell Host Microbe S1931-3128(21)00101-3. |
2021 |
Other |
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| Ebelt ND, et al. (2021) Collagenase-Expressing Salmonella Targets Major Collagens in Pancreatic Cancer and Improves Immune Checkpoint Blockade. Cancers (Basel) 13(14): 3565. |
2021 |
Cancer studies |
Pancreatic cancer |
| F Zhang F, et al. (2021) Crocin ameliorates atherosclerosis by promoting the reverse cholesterol transport and inhibiting the foam cell formation via regulating PPARγ/LXR-α. Cell Cycle Jan 3 doi: 10.1080/15384101.2021.2015669. |
2021 |
Other |
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| Fasolato L, et al. (2021) An Iron Shield to Protect Epigallocatehin-3-Gallate from Degradation: Multifunctional Self-Assembled Iron Oxide Nanocarrier Enhances Protein Kinase CK2 Intracellular Targeting and Inhibition. Pharmaceutics 13(8):1266. |
2021 |
Structural biology and protein interaction |
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| Frazier TW, et al. (2021) Cross-level analysis of molecular and neurobehavioral function in a prospective series of patients with germline heterozygous PTEN mutations with and without autism. Mol Autism 12(1):5. |
2021 |
Disease study: Biomarker research |
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| Freeman AJ, et al. (2021) HOIP limits anti‐tumor immunity by protecting against combined TNF and IFN‐gamma‐induced apoptosis. EMBO Rep Sep 1 doi: 10.15252/embr.202153391. |
2021 |
Cancer studies |
Skin cancer |
| Fu T, et al. (2021) Silencing lncRNA LINC01410 suppresses cell viability yet promotes apoptosis and sensitivity to temozolomide in glioblastoma cells by inactivating PTEN/AKT pathway via targeting miR-370-3p. Immunopharmacol Immunotoxicol Aug 26 doi: 10.1080/08923973.2021.1966031. |
2021 |
Cancer studies |
Brain cancer |
| Fujiwara S, et al. (2021) Chemical-gas sterilization of external surface of polymer-based prefilled syringes and its effect on stability of model therapeutic protein. J Pharm Sci Sep 6 doi: 10.1016/j.xphs.2021.09.003. |
2021 |
Structural biology/Protein interactions |
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| Furuyama W, et al. (2021) The Ebola virus soluble glycoprotein contributes to viral pathogenesis by activating the MAP kinase signaling pathway. PLoS Pathog 17(9):e1009937. |
2021 |
Cell signaling |
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| G Hu, et al. (2021) Light-driven CO2 sequestration in Escherichia coli to achieve theoretical yield of chemicals. Nature Catalysis 4: 395–406. |
2021 |
Microorganisms and model organisms |
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| Gao J, et al. (2021) Morroniside Promotes PGC-1α-Mediated Cholesterol Efflux in Sodium Palmitate or High Glucose-Induced Mouse Renal Tubular Epithelial Cells. Biomed Res Int 2021:9942152. |
2021 |
Other |
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| Gao X, et al. (2021) Gambogic acid protects LPS-induced apoptosis and inflammation in a cell model of neonatal pneumonia through the regulation of TrkA/Akt signaling pathway. BMC Pharmacol Toxicol 22(1):28 |
2021 |
Cell signaling |
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| Garrido‐Jimenez S, et al. (2021) p53 regulation by MDM2 contributes to self‐renewal and differentiation of basal stem cells in mouse and human airway epithelium. FASEB J 35(9):e21816. |
2021 |
Stem cells |
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| Gaul S, et al. (2021) Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells and induce pro-atherogenic effects. Sci Rep 11(1):15156. Other https://pubmed.ncbi.nlm.nih.gov/34312415/ |
2021 |
Other |
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| Ge X, et al. (2021) Protective effects of naringin on glucocorticoid-induced osteoporosis through regulating the PI3K/Akt/mTOR signaling pathway. Am J Transl Res 13(6):6330-6341. |
2021 |
Cell signaling |
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| George TA, et al. (2021) Liposome-encapsulated anthraquinone improves efficacy and safety in triple negative breast cancer. J Control Release Dec 8 doi: 10.1016/j.jconrel.2021.12.001. |
2021 |
Cancer studies |
Breast cancer |
| Grimbert L, et al. (2021) Spatiotemporal AMPKα2 deletion in mice induces cardiac dysfunction, fibrosis and cardiolipin remodeling associated with mitochondrial dysfunction in males only. Biol Sex Differ 12(1):52. |
2021 |
Mitochondrial studies |
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| Groveman BR, et al. (2021) Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt-Jakob disease . Sci Rep 11(1):5165. |
2021 |
Neurobiology |
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| Gu Y, et al. (2021) Therapeutic potential of a novel semi-synthetic-sulfated-polysaccharide to suppress inflammatory mediators in P. gingivalis LPS stimulated human monocytes/macrophages. J Inflamm (Lond) 18(1):26. |
2021 |
Drug mechanism |
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| Guettler J, et al. (2021) Maternal platelets pass interstices of trophoblast columns and are not activated by HLA-G in early human pregnancy.I144:103280. |
2021 |
Other |
|
| Guo Y, et al. (2021) miR-23a-3p is involved in drug resistance by directly targeting the influx drug transporter organic anion-transporting polypeptide 2. Childs Nerv Syst Mar 29 doi: 10.1007/s00381-021-05146-3. |
2021 |
Drug mechanism |
|
| Han H, et al. (2021) MiR-205 Promotes the Viability, Migration, and Tube Formation of Cervical Cancer Cells In Vitro by Targeting GATA3. Cancer Biother Radiopharm Mar 30 doi: 10.1089/cbr.2020.4184 |
2021 |
Cancer studies |
General |
| Hanafi M, et al. (2021) Discovery of a Napabucasin PROTAC as an Effective Degrader of the E3 Ligase ZFP91. J Med Chem 64(3):1626-1648. |
2021 |
Cell signaling |
|
| Hasan NA, et al. (2021) Measurable genomic changes in Mycobacterium avium subsp. hominissuis after long-term adaptation in Acanthamoeba lenticulata and reduced persistence in in macrophages. J Bacteriol Jan 11 doi: 10.1128/JB.00257-20. |
2021 |
Microorganisms and model organisms |
|
| Heltmann-Meyer S, et al. (2021) Gelatin methacryloyl is a slow degrading material allowing vascularization and long-term use in vivo. Biomed Mater Aug 18 doi: 10.1088/1748-605X/ac1e9d. |
2021 |
Method development |
|
| Hernandez JJ, et al. (2021) Dodging COVID-19 infection: low expression and localization of ACE2 and TMPRSS2 in multiple donor-derived lines of human umbilical cord-derived mesenchymal stem cells. J Transl Med 19(1):149 |
2021 |
Stem cells |
|
| Hernandez-Santini AC, et al. (2021) Methamphetamine facilitates pulmonary and splenic tissue injury and reduces T cell infiltration in C57BL/6 mice after antigenic challenge. Sci Rep 11(1):8207 |
2021 |
Other |
|
| Hesse J, et al. (2021) Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity. Purinergic Signal Dec 27 doi: 10.1007/s11302-021-09832-4. |
2021 |
Other |
|
| Hesse J, et al. (2021) Normoxic induction of HIF‐1α by adenosine‐A2BR signaling in epicardial stromal cells formed after myocardial infarction. FASEB J 35(5):e21517 |
2021 |
Cell signaling |
|
| Hong MJ, et al. (2021) Regulation of Glycosylphosphatidylinositol-Anchored Protein (GPI-AP) Expression by F-Box/LRR-Repeat (FBXL) Protein in Wheat (Triticum aestivum L.). Plants 10(8), 1606. |
2021 |
Plant sciences |
|
| Hsueh SC, et al. (2021) N-Adamantyl Phthalimidine: A New Thalidomide-like Drug That Lacks Cereblon Binding and Mitigates Neuronal and Synaptic Loss, Neuroinflammation, and Behavioral Deficits in Traumatic Brain Injury and LPS Challenge. |
2021 |
Neurobiology |
|
| Huang CT, et al. (2021) Intravitreal Injection of Long-Acting Pegylated Granulocyte Colony-Stimulating Factor Provides Neuroprotective Effects via Antioxidant Response in a Rat Model of Traumatic Optic Neuropathy. Antioxidants 10(12):1934. |
2021 |
Neurobiology |
|
| Huang L, et al. (2021) Circular RNA hsa_circ_0001598 promotes programmed death-ligand-1-mediated immune escape and trastuzumab resistance via sponging miR-1184 in breast cancer cells. Immunol Res Sep 24 doi: 10.1007/s12026-021-09237-w. |
2021 |
Cancer studies |
Breast cancer |
| Huang ZN, et al. (2021) Inhibition of p38 Mitogen–Activated Protein Kinase Ameliorates HAP40 Depletion–Induced Toxicity and Proteasomal Defect in Huntington's Disease Model. Mol Neurobiol Jan 25 doi: 10.1007/s12035-020-02280-y. |
2021 |
Neurobiology |
|
| Jackson TC, et al. (2021) Hippocampal and Prefrontal Cortical Brain Tissue Levels of Irisin and GDF15 Receptor Subunits in Children. Mol Neurobiol Jan 7 doi: 10.1007/s12035-020-02250-4. |
2021 |
Other |
|
| Janke U, et al. (2021) Reconstitution of Functional Integrin αIIbβ3 and Its Activation in Plasma Membrane-Mimetic Lipid Environments. Membranes (Basel) 11(7):499. |
2021 |
Structural biology |
|
| Ji L, et al. (2021) Enhancing L-malate production of Aspergillus oryzae by nitrogen regulation strategy. Appl Microbiol Biotechnol Apr 5 doi: 10.1007/s00253-021-11149-6. |
2021 |
Microorganisms and model organisms |
|
| Ji Z, et al. (2021) miR-7a Targets Insulin Receptor Substrate-2 Gene and Suppresses Viability and Invasion of Cells in Diabetic Retinopathy Mice via PI3K-Akt-VEGF Pathway. Diabetes Metab Syndr Obes 14:719-728. |
2021 |
Cell signaling |
|
| Jia, XB, et al. (2021) Lotus leaf flavonoids induce apoptosis of human lung cancer A549 cells through the ROS/p38 MAPK pathway. Biol Res 54(1):7. |
2021 |
Cancer studies |
Lung cancer |
| Jin H, et al. (2021) Gensenoside Rg1 Protects against Lipopolysaccharide-and D-galactose-induced Acute Liver Failure via Suppressing HMGB1-mediated TLR4-NF-κB Pathway. Mol Cell Probes Feb 19 doi: 10.1016/j.mcp.2021.101706. |
2021 |
Drug mechanism |
|
| Johar A, et al. (2021) Antibiotic Resistance and Virulence Gene Patterns Associated with Avian Pathogenic Escherichia coli (APEC) from Broiler Chickens in Qatar. Antibiotics 10(5): 564 |
2021 |
Microorganisms and model organisms |
|
| Jonuscheit S, et al. (2021) PARP Inhibitors Talazoparib and Niraparib Sensitize Melanoma Cells to Ionizing Radiation. Genes (Basel) 12(6):849. |
2021 |
Drug mechanism |
|
| Jung HJ, et al. (2021) TAM mediates adaptation of carbapenem-resistant Klebsiella pneumoniae to antimicrobial stress during host colonization and infection. PLoS Pathog 17(2):e1009309. |
2021 |
Microorganisms and model organisms |
|
| Jung YS, et al. (2021) Orphan nuclear receptor ERRγ regulates hepatic TGF-β2 expression and fibrogenic response in CCl4-induced acute liver injury. Arch Toxicol Jun 30 doi: 10.1007/s00204-021-03112-1. |
2021 |
Other |
|
| Kalogirou C, et al. (2021) MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer. Nat Commun 12(1):5066. |
2021 |
Cancer studies |
Prostate cancer |
| Kang H, et al. (2021) Downregulated CLIP3 induces radioresistance by enhancing stemness and glycolytic flux in glioblastoma. J Exp Clin Cancer Res 40(1):282. |
2021 |
Cancer studies |
Brain cancer |
| Kang JS, et al. (2021) Ingestion of Bis (2-ethylhexyl) phthalate (DEHP) during adolescence causes depressive-like behaviors through hypoactive glutamatergic signaling in the medial prefrontal cortex. Environ Pollut 289:117978. |
2021 |
Neurobiology |
|
| Kasson S, et al. (2021) Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes. PLoS One 16(6):e0254022. |
2021 |
Method development |
|
| Kaushal JB, et al. (2021) Repurposing Niclosamide for Targeting Pancreatic Cancer by Inhibiting Hh/Gli Non-Canonical Axis of Gsk3β. Cancers (Basel) 13(13):3105. |
2021 |
Cancer studies |
Pancreatic cancer |
| Khan SA, et al. (2021) Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening. Cell Rep 35(11):109233. |
2021 |
Stem cells |
|
| Kim DI, et al. (2021) Diesel Exhaust Particulates Enhances Susceptibility of LPS-Induced Acute Lung Injury through Upregulation of the IL-17 Cytokine-Derived TGF-β1/Collagen I Expression and Activation of NLRP3 Inflammasome Signaling in Mice. Biomolecules 11(1):E67. |
2021 |
Cell signaling |
|
| Kim EA, et al. (2021) Anti-Obesity Effect of Pine Needle Extract on High-Fat Diet-Induced Obese Mice. Plants (Basel) 10(5):837. |
2021 |
Plant sciences |
|
| Kim H, et al. (2022) Baiap3 regulates depressive behaviors in mice via attenuating dense core vesicle trafficking in subsets of prefrontal cortex neurons. Neurobiol Stress 16:100423. |
2021 |
Neurobiology |
|
| Kim JY, et al. (2021) Protective Effects of Bee Venom-Derived Phospholipase A2 against Cholestatic Liver Disease in Mice. Biomedicines 9(8):992. |
2021 |
Other |
|
| Kim YR, et al. (2021) Isoegomaketone from Perilla frutescens (L.) Britt Stimulates MAPK/ERK Pathway in Human Keratinocyte to Promote Skin Wound Healing. Evidence-Based Complementary and Alternative Medicine Feb 10 doi: 10.1155/2021/6642606. |
2021 |
Drug mechanism |
|
| King WT, et al. (2021) Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics. J Biol Chem Sep 13 doi: 10.1016/j.jbc.2021.101196. |
2021 |
Cell signaling |
|
| Kipkirui E, et al. (2021) Molecular characterization of enterotoxigenic Escherichia coli toxins and colonization factors in children under five years with acute diarrhea attending Kisii Teaching and Referral Hospital, Kenya. Trop Dis Travel Med Vaccines 7(1):31 |
2021 |
Microorganisms and model organisms |
|
| Kiss E, et al. (2021) Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines. Int J Mol Sci 22(7):3598. |
2021 |
Cell signaling |
|
| Klid S, et al. (2021) The angiogenic properties of human amniotic membrane stem cells are enhanced in gestational diabetes and associate with fetal adiposity. Stem Cell Res Ther 12(1):608. |
2021 |
Stem cells |
|
| Knorr DY, et al. (2021) Locust Hemolymph Conveys Erythropoietin-Like Cytoprotection via Activation of the Cytokine Receptor CRLF3. Front Physiol April 09 doi: 10.3389/fphys.2021.648245. |
2021 |
Cell signaling |
|
| Kohno T, et al. (2021) Translocation of LSR from tricellular corners causes macropinocytosis at cell–cell interface as a trigger for breaking out of contact inhibition. FASEB J 35(9):e21742 |
2021 |
Cancer studies |
Endometrial cancer |
| Kono M, et al. (2021) Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery. Cancer Immunol Immunother Apr 18 doi: 10.1007/s00262-021-02940-5. |
2021 |
Cancer studies |
General |
| Kouzminova EA, et al. (2021) Ultraviolet-induced RNA: DNA hybrids interfere with chromosomal DNA synthesis. Nucleic Acids Res Mar 10 doi: 10.1093/nar/gkab147. |
2021 |
Other |
|
| Kovačević S, et al. (2021) Fructose-Rich Diet Attenuates Stress-Induced Metabolic Disturbances in the Liver of Adult Female Rats. J Nutr Sep 11 doi: 10.1093/jn/nxab294. |
2021 |
Other |
|
| Krüger T, et al. (2021) Single-cell motile behaviour of Trypanosoma brucei in thin-layered fluid collectives. Eur Phys J E Soft Matter 44(3):37. |
2021 |
Microorganisms and model organisms |
|
| Latina V, et al. (2021) Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease. Acta Neuropathol Commun 9: 38 . |
2021 |
Neurobiology |
|
| Lee MH, et al. (2021) Anti-Obesity Effect of Licorice Acetone Extract in a Mouse Model of Obesity Induced by a High-Fat Diet. Food Suppl Biomater Health. 2021 Mar;1(1):e8. |
2021 |
Other |
|
| Lee MN, et al. (2021) Luteolin inhibits NLRP3 inflammasome activation via blocking ASC oligomerization. J Nutr Biochem Mar 8 doi: 10.1016/j.jnutbio.2021.108614. |
2021 |
Cell signaling |
|
| Lee Y, et al. (2021) Coordinate regulation of the senescent state by selective autophagy. Dev Cell 56(10):1512–1525.e7. |
2021 |
Other |
|
| Legscha KJ, et al. (2021) Δ133p53α enhances metabolic and cellular fitness of TCR-engineered T cells and promotes superior antitumor immunity. J Immunother Cancer (6):e001846. |
2021 |
Cancer studies |
Other |
| Li J, et al. (2021) Identification and validation of a regulatory mutation upstream of the BMP2 gene associated with carcass length in pigs. Genet Sel Evol 53(1):94. |
2021 |
Other |
|
| Li L, et al. (2021) Long non‑coding RNA HAND2‑AS1/miR‑106a/PTEN axis re‑sensitizes cisplatin‑resistant ovarian cells to cisplatin treatment. Mol Med Rep 24(5):762. |
2021 |
Cancer studies |
General |
| Li M, et al. (2021) Cytomegalovirus late transcription factor target sequence diversity orchestrates viral early to late transcription. |
2021 |
Microorganisms and model organisms |
|
| Li M, et al. (2021) Secreted Expression of mRNA‐Encoded Truncated ACE2 Variants for SARS‐CoV‐2 via Lipid‐Like Nanoassemblies. Adv Mater Jul 18 doi: 10.1002/adma.202101707. |
2021 |
Other |
|
| Li N, et al. (2021) Activation of Aquaporin 5 by carcinogenic Helicobacter pylori infection promotes epithelial‐mesenchymal transition via the MEK/ERK pathway. Helicobacter Jul 30 doi: 10.1111/hel.12842. |
2021 |
Cancer studies |
Gastric cancer |
| Li P, et al. (2021) Melatonin Attenuates ox-LDL-Induced Endothelial Dysfunction by Reducing ER Stress and Inhibiting JNK/Mff Signaling. Oxid Med Cell Longev Mar 4 doi:10.1155/2021/5589612. |
2021 |
Drug mechanism |
|
| Li Q, et al. (2021) In vivo PCSK9 gene editing using an all-in-one self-cleavage AAV-CRISPR system. Mol Ther Methods Clin Dev Feb 9 doi: 10.1016/j.omtm.2021.02.005. |
2021 |
CRISPR |
|
| Li S, et al. (2021) Gossypol ameliorates the IL-1β-induced apoptosis and inflammation in chondrocytes by suppressing the activation of TLR4/MyD88/NF-κB pathway via downregulating CX43. Tissue and Cell Aug 10 doi: 10.1016/j.tice.2021.101621. |
2021 |
Cell signaling |
|
| Liang M, et al. (2021) Near-infrared fluorescence-guided resection of micrometastases derived from esophageal squamous cell carcinoma using a c-Met-targeted probe in a preclinical xenograft model. J Control Release 332:171–183. |
2021 |
Cancer studies |
Squamous cell carcinoma |
| Lin C, et al. (2021) Plac1 promotes nasopharyngeal carcinoma cells proliferation, migration and invasion via Furin/NICD/PTEN pathway. Tissue Cell 69:101480. |
2021 |
Cancer studies |
General |
| Lin CC, et al. (2021) Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation. Nat Commun 12(1):3878. |
2021 |
Other |
|
| Lin MJ, et al. (2021) An Insulin-like Growth Factor-1 Conjugated Bombyx mori Silk Fibroin Film for Diabetic Wound Healing: Fabrication, Physicochemical Property Characterization, and and Dosage Optimization In Vitro and In Vivo. Pharmaceutics 13(9): 1459. |
2021 |
Drug mechanism |
|
| Lin YK, et al. (2021) Pterostilbene Increases LDL Metabolism in HL-1 Cardiomyocytes by Modulating the PCSK9/HNF1α/SREBP2/LDLR Signaling Cascade, Upregulating Epigenetic hsa-miR-335 and hsa-miR-6825, and LDL Receptor Expression. Antioxidants 10(8):1280. |
2021 |
Cell signaling |
|
| Lin YM, et al. (2021) Small Molecule Compound Nerolidol attenuates Hypertension induced hypertrophy in spontaneously hypertensive rats through modulation of Mel-18-IGF-IIR signaling. Phytomedicine Jan 4 doi: 10.1016/j.phymed.2020.153450 |
2021 |
Other |
|
| Lipońska A, MNF Yap. (2021) Hibernation-Promoting Factor Sequesters Staphylococcus aureus Ribosomes to Antagonize RNase R-Mediated Nucleolytic Degradation. mBio Jul 13 doi: 10.1128/mBio.00334-21. |
2021 |
Microorganisms and model organisms |
|
| Liu C, et al. (2021) Epigallocatechin gallate (EGCG) attenuates staphylococcal alpha-hemolysin (Hla)-induced NLRP3 inflammasome activation via ROS-MAPK pathways and EGCG-Hla interactions. Int Immunopharmacol 100:108170. |
2021 |
Microorganisms and model organisms |
|
| Liu C, et al. (2021) The Downregulation of Placental Lumican Promotes the Progression of Preeclampsia. Reprod Sci Jul 6 doi: 10.1007/s43032-021-00660-w. |
2021 |
Other |
|
| Liu D, et al. (2021) The mRNA Tether Model for Activation-Induced Deaminase and its Relevance for Ig Somatic Hypermutation and Class Switch Recombination. DNA Repair (Amst) 110:103271. |
2021 |
DNA repair |
|
| Liu Y, et al. (2021) Long noncoding RNA MIR22HG promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-125a-5p that targets N-Myc downstream-regulated gene 2 in late-onset hypogonadism. Lab Invest Aug 26 doi: 10.1038/s41374-021-00645-y. |
2021 |
Cell signaling |
|
| Liu Y, et al. (2021) microRNA-221 upregulates the expression of P-gp and Bcl-2 by activating the Stat3 pathway to promote doxorubicin resistance in osteosarcoma cells. |
2021 |
Cell signaling |
|
| Loeven NA, et al. (2021) The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection. mBio Sep 28 doi: 10.1128/mBio.02098-21. |
2021 |
Microorganisms and model organisms |
|
| Londoño PAC, et al. (2021) Is mRNA decapping by ApaH like phosphatases present in eukaryotes beyond the Kinetoplastida? BMC Ecol Evol 21(1):131. |
2021 |
Other |
|
| Lu L, et al. (2021) Therapeutic Effects of Sodium Para-Aminosalicylic Acid on Cognitive Deficits and Activated ERK1/2-p90RSK/NF-κB Inflammatory Pathway in Pb-Exposed Rats. Biol Trace Elem Res Aug 16 doi: 10.1007/s12011-021-02874-0. |
2021 |
Neurobiology |
|
| Lu Z, et al. (2021) PP2A protects podocytes against Adriamycin-induced injury and epithelial-to-mesenchymal transition via suppressing JIP4/p38-MAPK pathway. Cytotechnology Aug 13 doi: 10.1007/s10616-021-00484-1. |
2021 |
Cell signaling |
|
| Martire A, et al. (2021) P2X7 Receptor Agonist 2′(3′)-O-(4-Benzoylbenzoyl) ATP Differently Modulates Cell Viability and Corticostriatal Synaptic Transmission in Experimental Models of Huntington’s Disease. Front Pharmacol Feb 19 doi: 10.3389/fphar.2020.633861. |
2021 |
Neurobiology |
|
| Meng J, et al. (2021) MiR-15a-5p targets FOSL1 to inhibit proliferation and promote apoptosis of keratinocytes via MAPK/ERK pathway. J Tissue Viability Sept 1 doi: 10.1016/j.jtv.2021.08.006. |
2021 |
Cell signaling |
|
| Miyake T, et al. (2021) Nucleolar localization of c-Jun. FEBS J Sep 9 doi: 10.1111/febs.16187. |
2021 |
Structural biology/Protein interactions |
|
| MOHIUDDIN MD, et al. (2021) Cisplatin Activates the Growth Inhibitory Signaling Pathways by Enhancing the Production of Reactive Oxygen Species in Non-small Cell Lung Cancer Carrying an an EGFR Exon 19 Deletion. Cancer Genomics Proteomics 18(3 Suppl):471-486 |
2021 |
Cancer studies |
Lung cancer |
| Mohiuddin MD, et al. (2021) Cisplatin and Pemetrexed Have Distinctive Growth-inhibitory Effects in Monotherapy and Combination Therapy on KRAS-dependent A549 Lung Cancer Cells. Cancer Genomics Proteomics 18(4):579-590. |
2021 |
Cancer studies |
Lung cancer |
| Mohiuddin MD, et al. (2021) Paclitaxel Impedes EGFR-mutated PC9 Cell Growth via Reactive Oxygen Species-mediated DNA Damage and EGFR/PI3K/AKT/mTOR Signaling Pathway Suppression. Cancer Genomics Proteomics 18(5):645-659. |
2021 |
Cell signaling |
|
| Mohiuddin MD, et al. (2021) The Mechanisms of the Growth Inhibitory Effects of Paclitaxel on Gefitinib-resistant Non-small Cell Lung Cancer Cells. Cancer Genomics Proteomics 18(5):661-673. |
2021 |
Cancer studies |
Lung cancer |
| Munis AM, et al. (2021) RNA-Seq Analysis of the Human Surfactant Air-Liquid Interface Culture Reveals Alveolar Type II Cell-like Transcriptome. Mol Ther Methods Clin Dev Nov 24 doi: 10.1016/j.omtm.2021.11.06. |
2021 |
Other |
|
| Murata K, et al. (2021) Efficient induction of proximity-dependent labeling by biotin feeding in BMAL1-BioID knock-in mice. J Biochem May 12 doi: 10.1093/jb/mvab059 |
2021 |
Method development |
|
| Nabar NR, et al. (2021) LRRK2 is required for CD38-mediated NAADP-Ca2+ signaling and the downstream activation of TFEB (transcription factor EB) in immune cells. Autophagy Jul 27 doi: 10.1080/15548627.2021.1954779. |
2021 |
Cell signaling |
|
| Nagae F, et al. (2021) The lane-switch mechanism for nucleosome repositioning by DNA translocase. Nucleic Acids Res Aug 7 doi: 10.1093/nar/gkab664. |
2021 |
Structural biology and protein interaction |
|
| Nakase I, et al. (2021) Environmental pH stress influences cellular secretion and uptake of extracellular vesicles. FEBS Open Bio Feb 3 doi: 10.1002/2211-5463.13107. |
2021 |
Other |
|
| Negatu DA, et al. (2021) Piperidine-4-carboxamides target DNA gyrase in Mycobacterium abscessus. Antimicrob Agents Chemother May 17 doi: 10.1128/AAC.00676-21. |
2021 |
Microorganisms and model organisms |
|
| Nelson JW, et al. (2021) The gut microbiome contributes to blood‐brain barrier disruption in spontaneously hypertensive stroke prone rats. FASEB J 35(2):e21201. |
2021 |
Microorganisms and model organisms |
|
| Niyonizigiye I, et al. (2021) Aspilia africana CD Adams inhibits the production of lipopolysaccharide-induced inflammatory mediators in murine macrophage RAW264. 7 cells by suppressing the NF-κB and PI3K/Akt pathways. S Afr J Bot 141: 83–89 |
2021 |
Plant sciences |
|
| Nußbaum P, et al. (2021) The archaeal protein SepF is essential for cell division in Haloferax volcanii. Nat Commun 12(1):3469. |
2021 |
Microorganisms and model organisms |
|
| Okazawa M, et al. (2021) A 3-styrylchromone converted from trimebutine 3D pharmacophore possesses dual suppressive effects on RAGE and TLR4 signaling pathways. Biochem Biophys Res Commun 566:1-8. |
2021 |
Cell signaling |
|
| Oyama T, et al. (2021) Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells. Biochimie Sep 15 doi: 10.1016/j.biochi.2021.09.007. |
2021 |
Cancer studies |
Skin cancer |
| Parashar P, et al. (2021) Targeted biologic inhibition of both tumor cell-intrinsic and intercellular CLPTM1L/CRR9 mediated chemotherapeutic drug resistance. NPJ Precis Oncol 5(1):16. |
2021 |
Cancer studies |
Ovarian cancer |
| Park SK, et al. (2021) Ecklonia cava Attenuates PM2. 5-Induced Cognitive Decline through Mitochondrial Activation and Anti-Inflammatory Effect. Mar Drugs 19(3):131. |
2021 |
Neurobiology |
|
| Pastuschek J, et al. (2021) Molecular characteristics of established trophoblast-derived cell lines. Placenta Mar 4 doi: 10.1016/j.placenta.2021.02.022. |
2021 |
Other |
|
| Pourfarjam Y, et al. (2021) Structural and biochemical analysis of human ADP-ribosyl-acceptor hydrolase 3 (ARH3) reveals the basis of metal selectivity and different roles for the two Mg ions. J Biol Chem Apr 21 doi: 10.1016/j.jbc.2021.100692 |
2021 |
Structural biology/protein interactions |
|
| Purves TD, et al. (2021) Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia. Mol Brain 14(1):96. |
2021 |
Neurobiology |
|
| Qadeer A, et al. (2021) Transcriptional profiles of genes potentially involved in extracellular vesicle biogenesis in Schistosoma japonicum. Acta Trop 217:105851. |
2021 |
Other |
|
| Qin D, et al. (2021) LINC01207 promotes prostate cancer progression by sponging miR‑1182 to upregulate AKT3. Oncology Letters Dec 21 doi: 10.3892/ol.2021.13175. |
2021 |
Cancer studies |
General |
| Qiu H, et al. (2021) miR-30b-5p inhibits cancer progression and enhances cisplatin sensitivity in lung cancer through targeting LRP8. Apoptosis Mar 29 doi: 10.1007/s10495-021-01665-1. |
2021 |
Cancer studies |
Lung cancer |
| Qiu X, et al. (2021) Forkhead box O1 targeting replication factor C subunit 2 expression promotes glioma temozolomide resistance and survival. Ann Transl Med (8):692 |
2021 |
Cancer studies |
Brain cancer |
| Qiu Y, et al. (2021) RNA binding protein MEX3A controls G1/S transition via regulating the RB/E2F pathway in clear cell renal cell carcinoma. Mol Ther Nucleic Acids 27:241-255 |
2021 |
Cancer studies |
General |
| Radhakrishnan K, et al. (2021) Orphan nuclear receptor ERR-γ regulates hepatic FGF23 production in acute kidney injury. Proc Natl Acad Sci USA 118(16):e2022841118. |
2021 |
Other |
|
| Rao Y, et al. (2021) NeuroD1 induces microglial apoptosis and cannot induce microglia-to-neuron cross-lineage reprogramming. Neuron doi: 10.1016/j.neuron.2021.11.008. |
2021 |
Neurobiology |
|
| Ratti S, et al. (2021) Lamin B1 Accumulation's Effects on Autosomal Dominant Leukodystrophy (ADLD): Induction of Reactivity in the Astrocytes. Cells 10(10):2566. |
2021 |
Neurobiology |
|
| Rehnitz J, et al. (2021) FMR1 expression in human granulosa cells and variable ovarian response: control by epigenetic mechanisms. Mol Hum Reprod Jan 25 doi: 10.1093/molehr/gaab001. |
2021 |
Other |
|
| Rensi N, et al. (2021) Evaluation of TFR-1 Expression in Feline Mammary Cancer and In Vitro Antitumor Efficacy Study of Doxorubicin-Loaded H-Ferritin Nanocages. Cancers 13(6): 1248. |
2021 |
Cancer studies |
Breast cancer |
| Roberts A, et al. (2021) Electroactive reduced graphene oxide for highly sensitive detection of secretory non-structural 1 protein: A potential diagnostic biomarker for Japanese encephalitis virus. Biosens Bioelectron 198:113837. |
2021 |
Disease study |
Biomarker research |
| Rodriguez F, et al. (2021) Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. PLoS Negl Trop Dis 15(2):e0009147. |
2021 |
Microorganisms and model organisms |
|
| Russell JC, et al. (2021) Generation and characterization of a tractable C. elegans model of tauopathy. Geroscience Sep 18 doi: 10.1007/s11357-021-00436-9. |
2021 |
Neurobiology |
|
| Ryota C. et al. (2021) Divergence in chondrogenic potential between in vitro and in vivo of adipose-and synovial-stem cells from mouse and human. Stem Cell Res Ther 12(1):405. |
2021 |
Stem cells |
|
| Santerre M, et al. (2021) HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons. Autophagy Apr 23 doi: 10.1080/15548627.2021.1915641. |
2021 |
Neurobiology |
|
| Santos MF, et al. (2021) Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum. J Extracell Vesicles 10(10):e12132. |
2021 |
Other |
|
| Savitr C, et al. (2021) M2 Macrophage-Derived Concentrated Conditioned Media Significantly Improves Skin Wound Healing. Tissue Eng Regen Med Dec 28. doi: 10.1007/s13770-021-00414-4. |
2021 |
Other |
|
| Senji Laxme RR, et al. (2021) Biogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy. PLoS Negl Trop Dis 15(2):e0009150. |
2021 |
Other |
|
| Seno S, et al. (2021) β-Thujaplicin Enhances TRAIL-Induced Apoptosis via the Dual Effects of XIAP Inhibition and Degradation in NCI-H460 Human Lung Cancer Cells. Medicines 8(6):26. |
2021 |
Cancer studies |
Lung cancer |
| Shih HJ, et al. (2021) Differential expression of hypoxia-inducible factors related to the invasiveness of epithelial ovarian cancer. Sci Rep 11(1):22925. |
2021 |
Cancer studies |
General |
| Shih HJ, et al. (2021) Simultaneous Inhibition of Three Major Cytokines and Its Therapeutic Effects: A Peptide-Based Novel Therapy against Endotoxemia in Mice. J Pers Med 11(5): 436. |
2021 |
Drug mechanism |
|
| Shirsath K, et al. (2021) Chronic photoperiodic manipulation induced chronodisruption upregulates HSP60 during early pro-atherogenic remodeling in thoracic aorta of C57BL/6J mice. The Journal of Basic and Applied Zoology 82:9. |
2021 |
Other |
|
| Shirsath K, et al. (2021) HSP60 knockdown exerts differential response in endothelial cells and monocyte derived macrophages during atherogenic transformation. Sci Rep 11(1):1086. |
2021 |
Other |
|
| Siwach M, et al. (2021) An organelle-tethering mechanism couples flagellation to cell division in bacteria. Dev Cell Feb 17 doi: 10.1016/j.devcel.2021.01.013. |
2021 |
Microorganisms and model organisms |
|
| Skertich NJ, et al. (2021) Expression of Programmed Death Ligand 1 in Drug Resistant Osteosarcoma: An Exploratory Study. Surg Open Sci doi: 10.1016/j.sopen.2021.07.001. |
2021 |
Cancer studies |
General |
| Slominski AT, et al. (2021) Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs). Sci Rep 11(1):8002. |
2021 |
Other |
|
| Souza COS, et al. (2021) NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses. iScience May 18 doi.org/10.1016/j.isci.2021.102548 |
2021 |
Other |
|
| Spampinato S, et al. (2021) Protective effect of the sphingosine-1 phosphate receptor agonist siponimod on disrupted blood brain barrier function. Biochem Pharmacol 186:114465. |
2021 |
Neurobiology |
|
| Srinivasan A, et al. (2021) Preclinical Development of Plant‐based Oral Immune Modulatory Therapy for Hemophilia B. Plant Biotechnol J May 5 doi: 10.1111/pbi.13608 |
2021 |
Other |
|
| Sripathi SR, et al. (2021) Epithelial to mesenchymal transition (EMT) of human stem cell-derived retinal pigment epithelium shares commonalities with malignancy-associated EMT: a proteomic analysis. Mol Cell Proteomics Aug 26 doi: 10.1016/j.mcpro.2021.100131. |
2021 |
Stem cells |
|
| Srivastava T, et al. (2021) A mouse model of prenatal exposure to Interleukin-6 to study the developmental origin of health and disease. Sci Rep 11(1):13260. |
2021 |
Other |
|
| Stabel JR, et al. (2021) Reduced tissue colonization of Mycobacterium avium subsp. paratuberculosis in neonatal calves vaccinated with a cocktail of recombinant proteins. Vaccine 39(23):3131–3140 |
2021 |
Other |
|
| Su N , et al. (2021) Circ_0001666 affects miR-620/WNK2 axis to inhibit breast cancer progression. Genes Genomics Jun 1 doi: 10.1007/s13258-021-01114-y |
2021 |
Cancer studies |
Breast cancer |
| Sun L, et al. (2021) Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation via NLRP3 signal inhibition in aged mice. CNS Neurosci Ther Dec 23. doi: 10.1111/cns.13784. |
2021 |
Neurobiology |
|
| Sunagar K, et al. (2021) A Wolf in Another Wolf's Clothing: Post-Genomic Regulation Dictates Venom Profiles of Medically-Important Cryptic Kraits in India. Toxins (Basel) 13(1):69. |
2021 |
Other |
|
| Suthon S, et al. (2021) Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in osteoblasts. Am J Hum Genet Dec 2 doi: 10.1016/j.ajhg.2021.11.018. |
2021 |
Disease study |
Biomarker research |
| Suzuki Y, et al. (2021) Pathogenicity and genomic features of vapN-harboring Rhodococcus equi isolated from human patients. Int J Med Microbiol July 2 doi: 10.1016/j.ijmm.2021.151519. |
2021 |
Other |
|
| Switzer CH, et al. (2021) Cysteine trisulfide oxidizes protein thiols and induces electrophilic stress in human cells. Redox Biol 47:102155. |
2021 |
Cell signaling |
|
| Szatmári Á, et al. (2021) A pattern-triggered immunity-related phenolic, acetosyringone, boosts rapid inhibition of a diverse set of plant pathogenic bacteria. BMC Plant Biol 21(1):153. |
2021 |
Plant sciences |
|
| Tada T, et al. (2021) Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes. mBio Jun 1 doi: 10.1128/mBio.00696-21. |
2021 |
Other |
|
| Takahashi M, et al. (2021) Quick and Easy Assembly of a One-Step qRT-PCR Kit for COVID-19 Diagnostics Using In-House Enzymes. ACS Omega 6(11): 7374–7386. |
2021 |
Method development |
|
| Takahashi Y, et al. (2021) Direct administration of the non-competitive interleukin-1 receptor antagonist rytvela transiently reduced intrauterine inflammation in an extremely preterm sheep model of chorioamnionitis. PLoS One 16(9):e0257847. |
2021 |
Other |
|
| Tanaka H, et al. (2021) Human colorectal cancer-associated carbohydrate antigen on annexin A2 protein. J Mol Med (Berl) Apr 27 doi: 10.1007/s00109-021-02077-z |
2021 |
Cancer studies |
Collorectal cancer |
| Tang M, et al. (2021) Glycyrrhetinic acid remodels the tumor microenvironment and synergizes with doxorubicin for breast cancer treatment in a murine model. Nanotechnology Jan 27. doi: 10.1088/1361-6528/abe076. |
2021 |
Cancer studies |
Breast cancer |
| Taş İ, et al. (2021) Physciosporin Suppresses Mitochondrial Respiration, Aerobic Glycolysis, and Tumorigenesis in Breast Cancer. Phytomedicine Jul 18 doi: 10.1016/j.phymed.2021.153674. |
2021 |
Cancer studies |
Breast cancer |
| Tassone A, et al. (2021) Vesicular Acetylcholine Transporter Alters Cholinergic Tone and Synaptic Plasticity in DYT1 Dystonia. Mov Disord Jun 26 doi: 10.1002/mds.28698 |
2021 |
Neurobiology |
|
| Teti G, et al. (2021) Cellular senescence in vascular wall mesenchymal stromal cells, a possible contribution to the development of aortic aneurysm. Mech Ageing Dev 197:111515. |
2021 |
Other |
|
| Tong X, et al. (2021) RNF144A-AS1 promotes the development of glioma cells by targeting miR-665/HMGA1 axis. Neurosci Lett Sep 21 doi: 10.1016/j.neulet.2021.136259. |
2021 |
Cancer studies |
General |
| Toychiev AH, et al. (2021) Gap Junctional Coupling Between Retinal Astrocytes Exacerbates Neuronal Damage in Ischemia-Reperfusion Injury. Invest Ophthalmol Vis Sci 62(14):27. |
2021 |
Neurobiology |
|
| Ueda H, et al. (2021) Synthesis of sp [3]-Rich Chiral Bicyclo [3.3. 1] nonanes for Chemical Space Expansion and Study of Biological Activities. Bioorg Med Chem 54:116561. |
2021 |
Other |
|
| Urrutia Iñiguez J, et al. (2021) An epilepsy-causing mutation leads to co-translational misfolding of the Kv7. 2 channel. BMC Biol 19(1):109. |
2021 |
Neurobiology |
|
| V Kumar, et al. (2021) Polymeric nanomedicine for overcoming resistance mechanisms in hedgehog and Myc-amplified medulloblastoma. Biomaterials 278:121138. |
2021 |
Drug mechanism |
|
| Vakilian S, et al. (2021) An engineered microfluidic blood‐brain barrier model to evaluate the anti‐metastatic activity of β‐boswellic acid. Biotechnol J Jul 27 doi: 10.1002/biot.202100044 |
2021 |
Cancer studies |
General |
| Valenzuela-Muñoz V, et al. (2021) Transcriptome and morphological analysis in Caligus rogercresseyi uncover the effects of Atlantic salmon vaccination with IPath®. |
2021 |
Other |
|
| Vester SK, et al. (2021) Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation. J Biol Chem Mar 4 doi: 10.1016/j.jbc.2021.100513. |
2021 |
Structural biology/protein interaction |
|
| Wan S, et al. (2021) MicroRNA-140-3p represses the proliferation, migration, invasion and angiogenesis of lung adenocarcinoma cells via targeting TYMS (Thymidylate Synthetase). Bioengineered Nov 24 doi: 10.1080/21655979.2021.2009422 |
2021 |
Cancer studies |
Lung cancer |
| Wang J, et al. (2021) MicroRNA-532-5p upregulation protects neurological deficits after ischemic stroke through inhibition of BTB and CNC homology 1. Int Immunopharmacol 100:108003. |
2021 |
Neurobiology |
|
| Wang K, et al. (2021) Downregulation of DEAD-box helicase 21 (DDX21) inhibits proliferation, cell cycle, and tumor growth in colorectal cancer via targeting cell division cycle 5-like (CDC5L). Bioengineered 12(2):12647-12658. |
2021 |
Cancer studies |
Colorectal cancer |
| Wang P, et al. (2021) Loss of haspin suppresses cancer cell proliferation by interfering with cell cycle progression at multiple stages. FASEB J 35(10):e21923. |
2021 |
Cancer studies |
General |
| Wang X, et al. (2021) Staphylococcus aureus Extracellular Vesicles: A Story of Toxicity and the Stress of 2020. Toxins (Basel) 13(2):E75. |
2021 |
Microorganisms and model organisms |
|
| Wang Y, et al. (2021) MYPT1, regulated by miR-19b-3p inhibits the progression of non-small cell lung cancer via inhibiting the activation of wnt/β-catenin signaling. Life Sci May 5 doi: 10.1016/j.lfs.2021.119573 |
2021 |
Cancer studies |
Lung cancer |
| Wei, Y et al. (2021) Acacetin ameliorates insulin resistance in obesity mice through regulating Treg/Th17 balance via MiR-23b-3p/NEU1 Axis. BMC Endocr Disord 21(1):57. |
2021 |
Cell signaling |
|
| Welch JL, et al. (2021) Human T cells express Angiotensin Converting Enzyme 2 at levels sufficient to interact with the SARS-CoV-2 Spike protein. J Infect Dis Dec 16 doi: 10.1093/infdis/jiab595. |
2021 |
Microorganisms and model organisms |
|
| Wen L, et al. (2021) The lignan sesamin suppresses TRIM44 and exerts antitumor activity to esophageal squamous cell carcinoma. Chem Biol Drug Des Aug 19. doi: 10.1111/cbdd.13937. |
2021 |
Cancer studies |
Squamous cell carcinoma |
| Wu CL, et al. (2021) Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis. Nat Commun 12(1):362. |
2021 |
Stem cells |
|
| Xu J, et al. (2021) Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons. J Neuroinflammation 18(1):106 |
2021 |
Neurobiology |
|
| Yahya G, et al. (2021) Profiling the physiological pitfalls of anti‐hepatitis C direct‐acting agents in budding yeast. Microb Biotechnol Aug 11 doi: 10.1111/1751-7915.13904. |
2021 |
Microorganisms and model organisms |
|
| Yan L, et al. (2021) Fisetin ameliorates atherosclerosis by regulating PCSK9 and LOX‑1 in apoE‑/‑mice. Exp Ther Med 21:25. |
2021 |
Drug mechanism |
|
| Yang C, et al. (2021) Nuclear IGF1R interacts with NuMA and regulates 53BP1‑dependent DNA double‑strand break repair in colorectal cancer. Oncol Rep 46(2):168. |
2021 |
Cancer studies |
Colorectal cancer |
| Yang W, et al. (2021) Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response. Biochem Pharmacol 195:114863. |
2021 |
Other |
|
| Yang X, et al. (2021) Identification and verification of HCAR3 and INSL5 as new potential therapeutic targets of colorectal cancer. World J Surg Oncol 19(1):248. |
2021 |
Cancer studies |
Colorectal cancer |
| Yang Y, et al. (2021) Dysregulated APP expression and α-secretase processing of APP is involved in manganese-induced cognitive impairment. Ecotoxicol Environ Saf 220:112365. |
2021 |
Other |
|
| Yankel C, et al. (2020) Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST. Sci Rep 10(1):15791. |
2021 |
Method development |
|
| Yazgili AS, et al. (2021) In-gel proteasome assay to determine the activity, amount, and composition of proteasome complexes from mammalian cells or tissues. STAR Protoc 2(2): 100526 |
2021 |
Method development |
|
| Yeini E, et al. (2021) P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression. Nat Commun 12(1):1912. |
2021 |
Cancer studies |
Brain cancer |
| Yi H, et al. (2021) Knockdown of long non‑coding RNA DLEU2 suppresses idiopathic pulmonary fibrosis by regulating the microRNA‑369‑3p/TRIM2 axis. Int J Mol Med 47(5):80. |
2021 |
Other |
|
| Yoo SK, et al. (2021) Immature Persimmon Suppresses Amyloid Beta (Aβ) Mediated Cognitive Dysfunction via Tau Pathology in ICR Mice. Curr Issues Mol Biol 43(1):405-422. |
2021 |
Neurobiology |
|
| Young N, et al. (2021) Biallelic SYNE2 Missense Mutations Leading to Nesprin-2 Giant Hypo-Expression Are Associated with Intellectual Disability and Autism. Genes 12(9): 1294. |
2021 |
Neurobiology |
|
| Yousefzadeh MJ, et al. (2021) An aged immune system drives senescence and ageing of solid organs. Nature May 12 doi: 10.1038/s41586-021-03547-7 |
2021 |
Other |
|
| Yu C, et al. (2021) Protective Effect and Mechanism of Schisandra Chinensis Extract on Retinal Photoreceptor Cell Injury. Farmacia 69(1): 107-112. |
2021 |
Other |
|
| Yu S, et al. (2021) A Protein from Dioscorea polystachya (Chinese Yam) Improves Hydrocortisone-Induced Testicular Dysfunction by Alleviating Leydig Cell Injury via Upregulation of the Nrf2 Pathway. Oxid Med Cell Longev 2021:3575016 |
2021 |
Cell signaling |
|
| Yu Y, et al. (2021) Prodrug Nanomedicine Inhibits Chemotherapy-Induced Proliferative Burst by Altering the Deleterious Intercellular Communication. ACS Nano Jan 7 doi: 10.1021/acsnano.0c07113. |
2021 |
Cancer studies |
General |
| Yuk H, et al. (2021) Necrostatin-1 Prevents Ferroptosis in a RIPK1-and IDO-Independent Manner in Hepatocellular Carcinoma. Antioxidants 10(9): 1347. |
2021 |
Cancer studies |
Liver cancer |
| Zabegina L, et al. (2021) A New Approach for Prostate Cancer Diagnosis by miRNA Profiling of Prostate-Derived Plasma Small Extracellular Vesicles. Cells 10(9): 2372. |
2021 |
Cancer studies |
General |
| Zhai L, et al. (2021) Overexpressed Versican Promoted Cell Multiplication, Migration and Invasion in Gastric Cancer. Tissue Cell 73:101611. |
2021 |
Cancer studies |
Gastric cancer |
| Zhang L, et al. (2021) MiR-22 regulated T cell differentiation and hepatocellular carcinoma growth by directly targeting Jarid2. Am J Cancer Res 11(5):2159-2173. |
2021 |
Cancer studies |
Liver cancer |
| Zhang M, et al. (2021) Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases. Nat Commun 12(1):2344. |
2021 |
Other |
|
| Zhang X, et la. (2021) Transcranial photobiomodulation therapy ameliorates perioperative neurocognitive disorder through modulation of mitochondrial function in aged mice. Neuroscience Dec 31 doi: 10.1016/j.neuroscience.2021.12.033. |
2021 |
Neurobiology |
|
| Zhang Y, et al. (2021) Cerebellar Kv3. 3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1. Nat Commun 12(1):1731 |
2021 |
Cell signaling |
|
| Zhang Y, et al. (2021) Lycium barbarum Polysaccharides Promotes Mitochondrial Biogenesis and Energy Balance in a NAFLD Cell Model. Chin J Integr Med Dec 7 doi: 10.1007/s11655-021-3309-6. |
2021 |
Mitochondrial studies |
|
| Zhang Y, et al. (2021) Overexpression of miR-99a Alleviates Intestinal Mucosal Barrier Injury in Rats with Severe Acute Pancreatitis. J Interferon Cytokine Res 41(2):72-80. |
2021 |
Other |
|
| Zhang YY, et al. (2021) Chimeric antigen-guiding extracellular vesicles eliminate antigen-specific Th2 cells in subjects with food allergy. World Allergy Organ J 14(3): 100522. |
2021 |
Other |
|
| Zhao Y, et al. (2021) Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF‐κB signaling. Immun Inflamm Dis Jun 5 doi: 10.1002/iid3.465. |
2021 |
Cell signaling |
|
| Zhou X, et al. (2021) UTMD-mediated delivery of MiR-21-5p inhibitor suppresses the development of lung cancer. Tissue Cell 74:101719. |
2021 |
Cancer studies |
Lung cancer |
| Zhu J, et al. (2021) Predictive Models for HCC Prognosis, Recurrence Risk, and Immune Infiltration Based on Two Exosomal Genes: MYL6B and THOC2. J Inflamm Res 14:4089-4109. |
2021 |
Cancer studies |
Liver cancer |
| Zimmer A, et al. (2021) Thioredoxin system activation is associated with the progression of experimental pulmonary arterial hypertension. Life Sci 284:119917. |
2021 |
Cell signaling |
|
| Adhikari A and Davie JK (2020) The PRC2 complex directly regulates the cell cycle and controls proliferation in skeletal muscle. Cell Cycle Aug 20 doi: 10.1080/15384101.2020.1806448. |
2020 |
Other |
|
| Adhikari XY, et al. (2020) IFN-γ and CIITA modulate IL-6 expression in skeletal muscle. Cytokine: X (2)2:100023 |
2020 |
Other |
|
| Ali G, et al. (2020) Keratinocytes derived from patient-specific induced pluripotent stem cells recapitulate the genetic signature of psoriasis disease. Stem Cells Dev Jan 29 doi: 10.1089/scd.2019.0150. |
2020 |
Disease study: Biomarker research |
|
| Almacellas E, et al. (2020) Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability. Autophagy Jun 23 doi: 10.1080/15548627.2020.1764727. |
2020 |
Other |
|
| An N, et al. (2020) SEZ6L2 Knockdown Impairs Tumour Growth by Promoting Caspase-Dependent Apoptosis in Colorectal Cancer. J Cell Mol Med Feb 27 doi: 10.1111/jcmm.15082. |
2020 |
Cell signaling |
|
| Arreal L, et al. (2020) Targeting PML in Triple Negative Breast Cancer Elicits Growth Suppression and Senescence. Cell Death Differ 27:1186–1199. |
2020 |
Cancer |
Breast |
| Barilli A, et al. (2020) Organic Cation Transporters (OCTs) in EpiAirway™, A Cellular Model of Normal Human Bronchial Epithelium. Biomedicines 8(5):127. |
2020 |
Other |
|
| Bartish M, et al. (2020) MNK2 governs the macrophage antiinflammatory phenotype. Proc Natl Acad Sci U S A Oct 19 doi: 10.1073/pnas.1920377117. |
2020 |
Cell signaling |
|
| Baxter K, et al. (2020) Towards defining global ecotypes of the toxic cyanobacterium Raphidiopsis raciborskii. Applied Phycology Aug 6 doi: 10.1080/26388081.2020.1740891. |
2020 |
Microorganisms and model organisms |
|
| Bayazid AB, et al. (2020) Antioxidant, Anti-inflammatory, and Antiproliferative Activity of Mori Cortex Radicis Extracts. Natural Prod Comm 15(1):1–8. |
2020 |
Other |
|
| Bhattacharjee P, et al. (2020) Synthetic Carboline Compounds Targeting Protein: Biophysical and Biological Perspective. J Biomol Struct Dyn June 1 doi: 10.1080/07391102.2020.1769732. |
2020 |
Other |
|
| Bittmann J, et al. (2020) An Advanced Cell Cycle Tag Toolbox Reveals Principles Underlying Temporal Control of Structure-Selective Nucleases. Elife 9:e52459. |
2020 |
Other |
|
| Bonar MM, et al. (2020) Nanoscale flow cytometry reveals interpatient variability in HIV protease activity that correlates with viral infectivity and identifies drug-resistant viruses. Sci Rep 10(1):18101. |
2020 |
Method development |
|
| Bouza AA, et al. (2020) Sodium channel β1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis. J Biol Chem 295(30):10380–10393. |
2020 |
Other |
|
| Chen D, et al. (2020) Cancer Cell Membrane-Decorated Zeolitic-Imidazolate Frameworks Codelivering Cisplatin and Oleanolic Acid Induce Apoptosis and Reversed Multidrug Resistance on Bladder Carcinoma Cells. ACS Omega 5(2):995-1002. |
2020 |
Cancer |
Bladder |
| Chen D, et al. (2020) Downregulating miR-96-5p promotes proliferation, migration, and invasion, and inhibits apoptosis in human trophoblast cells via targeting DDAH1. Reprod BioI 21(1):100474. |
2020 |
Cell signaling |
|
| Chen Q, et al. (2020) Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair. Cell Rep 31(13):107828. |
2020 |
Other |
|
| Cheng L, et al. (2020) Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway. Metabolites 10(3):E90. |
2020 |
Cell signaling |
|
| Ciu S, et al. (2020) LncRNA MAGI2-AS3 is down-regulated in intervertebral disc degeneration and participates in the regulation of FasL expression in nucleus pulposus cells. BMC Musculoskelet Disord 21:149. |
2020 |
Other |
|
| Darvish-Ghane S, et al. (2020) D1 receptors in the anterior cingulate cortex modulate basal mechanical sensitivity threshold and glutamatergic synaptic transmission. Mol Brain 13(1):121. |
2020 |
Neurobiology |
|
| Darvishi E, et al. (2020) Molecular Mechanisms of Guadecitabine Induced FGFR4 Down Regulation in Alveolar Rhabdomyosarcomas. Neoplasia 22(7):274−282. |
2020 |
Cancer |
General |
| de Oliveira BH, et al. (2020) ET-B receptors involvement in peripheral opioid analgesia induced by light-emitting diode photobiomodulation in male and female mice. J Photochem Photobiol B 214:112104. |
2020 |
Other |
|
| Delvaux NA, et al. (2020) Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Anal Biochem Aug 9 doi: 10.1016/j.ab.2020.113895. |
2020 |
Method development |
|
| Ding Q, et al. (2020) Light-powered Escherichia Coli Cell Division for Chemical Production. Nat Commun 11:2262. |
2020 |
Microorganisms and model organisms |
|
| Dopie J, et al. (2020) Tyramide signal amplification mass spectrometry (TSA-MS) ratio identifies nuclear speckle proteins. J Cell Biol 219(9):e201910207. |
2020 |
Method development |
|
| Du P, et al. (2020) Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer. Cell Death Dis 11(9):761. |
2020 |
Cancer studies: Breast cancer |
|
| Dye BK, et al. (2020) Smooth Muscle α-Actin Expression in Mitral Valve Interstitial Cells is Important for Mediating Extracellular Matrix Remodeling. J Cardiovasc Dev Dis 7(3):E32. |
2020 |
Other |
|
| Ebelt ND, et al. (2020) 5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma. Front Immunol 11:538. |
2020 |
Cancer |
Pancreatic |
| Eccardt AM, et al. (2020) A Peroxidase Mimetic Protects Skeletal Muscle Cells From Peroxide Challenge and Stimulates Insulin Signaling. Am J Physiol Cell Physiol 318(6):C1214−C1225. |
2020 |
Other |
|
| Eichler CE, et al. (2020) Compartmentalized oskar degradation in the germ plasm safeguards germline development. Elife 9:e49988. |
2020 |
Other |
|
| Elsayed AK, et al. (2020) Derivation of a Human Induced Pluripotent Stem Cell Line (QBRIi007-A) From a Patient Carrying a Homozygous Intronic Mutation (c.613-7T>G) in the SLC2A2 Gene. Stem Cell Res 44:101736. |
2020 |
Stem cells |
|
| Eltai NO, et al. (2020) Antibiotic Resistance and Virulence Patterns of Pathogenic Escherichia Coli Strains Associated With Acute Gastroenteritis Among Children in Qatar. BMC Microbiol 20(1):54. |
2020 |
Microorganisms and model organisms |
|
| Esaki M, et al. (2020) The effect of dihydropyrazines on lipopolysaccharide-stimulated human hepatoma HepG2 cells via regulating the TLR4-MyD88-mediated NF-κB signaling pathway. J Toxicol Sci 45(7):401–409. |
2020 |
Cell signaling |
|
| Fan Q, et al. (2020) Paeoniflorin Modulates Gut Microbial Production of Indole-3-lactate and Epithelial Autophagy to Alleviate Colitis in Mice. Phytomedicine Sept 19 doi: 10.1016/j.phymed.2020.153345 |
2020 |
Other |
|
| Foliaki ST, et al. (2020) Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease. |
2020 |
Disease study: Biomarker research |
|
| Forstner D, et al. (2020) Platelet-derived factors impair placental chorionic gonadotropin beta-subunit synthesis. J Mol Med (Berl) 98(2):193−207. |
2020 |
Cell signaling |
|
| Francis R, et al. (2020) Glycolytic Inhibitor 2-deoxyglucose Suppresses Inflammatory Response in Innate Immune Cells and Experimental Staphylococcal Endophthalmitis. Exp Eye Res 197:108079. |
2020 |
Other |
|
| Furuyama W, et al. (2020) A complement component C1q-mediated mechanism of antibody-dependent enhancement of Ebola virus infection. PLoS Negl Trop Dis 14(9):e0008602. |
2020 |
Microorganisms and model organisms |
|
| Fuseya S, et al. (2020) Mice lacking core 1-derived O-glycan in podocytes develop transient proteinuria, resulting in focal segmental glomerulosclerosis. Biochem Biophys Res Comm 523(4):1007−1013. |
2020 |
Other |
|
| Gahamanyi N, et al. (2020) Susceptibility of Campylobacter Strains to Selected Natural Products and Frontline Antibiotics. Antibiotics (Basel) 9(11):E790. |
2020 |
Microorganisms and model organisms |
|
| Gan C, et al. (2020) Untargeted metabolomics study and pro-apoptotic properties of B-norcholesteryl benzimidazole compounds in ovarian cancer SKOV3 cells. J Steroid Biochem Mol Biol 202:105709. |
2020 |
Cancer studies |
Ovarian |
| Gibbons GS, et al. (2020) Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library. Eur J Med Chem 189:112023. |
2020 |
Method development |
|
| Goldstein T, et al. (2020) Spillover of ebolaviruses into people in Eastern Democratic Republic of Congo prior to the 2018 Ebola virus disease outbreak. One Health Outlook 2(1):21. |
2020 |
Other |
|
| Guo J, et al. (2020) RNA-binding proteins tristetraprolin and human antigen R are novel modulators of podocyte injury in diabetic kidney disease. Cell Death Dis 11(6):413. |
2020 |
Other |
|
| Han HJ, et al. (2020) Anti-Melanogenic Effect of Ethanolic Extract of Sorghum bicolor on IBMX-Induced Melanogenesis in B16/F10 Melanoma Cells. Nutrients 12(3):E832. |
2020 |
Cancer |
Skin |
| Han S, et al. (2020) Ultrasound Stimulation Increases Neurite Regeneration in Injured Dorsal Root Ganglion Neurons through Mammalian Target of Rapamycin Activation. Brain Sci 10(7):E409. |
2020 |
Cell signaling |
|
| Harmouch E, et al. (2020) Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes. Sci Rep 10(1):13750 |
2020 |
Cancer studies |
Brain cancer |
| Hasan ASH, et al. (2020) Characterization of a bicistronic knock-in reporter mouse model for investigating the role of CABLES2 in vivo. Exp Anim Aug 11 doi: 10.1538/expanim.20-0063. |
2020 |
Microorganisms and model organisms |
|
| Hashiguchi H, et al. (2020) Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with α1, 2-fucose in the small intestine. Arch Biochem Biophys 695:108653. |
2020 |
Microorganisms and model organisms |
|
| He X, et al. (2020) Hypoxia improved vasculogenesis in distraction osteogenesis through Mesenchymal-Epithelial transition (MET), Wnt/β-catenin signaling pathway, and autophagy. Acta Histochemica 122:151593. |
2020 |
Cell signaling |
|
| Hong MJ, et al. (2020) Isolation and characterization of kelch repeat-containing F-box proteins from colored wheat. Mol Biol Rep 47(2):1129−1141. |
2020 |
Plant sciences |
|
| Houston R, et al. (2020) Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses. PLoS Biol 18(11):e3000981. |
2020 |
CRISPR |
|
| Huo J, et al. (2020) Rewiring carbon flux in Escherichia coli using a bifunctional molecular switch. Metab Eng 61:47–57. |
2020 |
Microorganisms and model organisms |
|
| Ihara K, et al. (2020) A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice. Sci Rep 10(1):17894. |
2020 |
Other |
|
| Jung Y and Yoon M. (2020) Oxytocin Receptor Expression in Stallion Testes and Epididymides. Domest Anim Endocrinol Sept 12 doi: 10.1016/j.domaniend.2020.106562 |
2020 |
Other |
|
| JY Kim JY, et al. (2020) Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice. Antioxidants (Basel) 9(12):E1271. |
2020 |
Other |
|
| Kalchiem-Dekel O, et al. (2020) Apolipoprotein E Signals via TLR4 to Induce CXCL5 Secretion by Asthmatic Airway Epithelial Cells. Am J Respir Cell Mol Biol Apr 27 doi: 10.1165/rcmb.2019-0209OC. |
2020 |
Cell signaling |
|
| Kang DR, Shim KS. (2020) Early heat exposure effect on the heat shock proteins in broilers under acute heat stress. Poult Sci Dec 26 doi:10.1016/j.psj.2020.12.061. |
2020 |
Other |
|
| Kim D, et al. (2020) Muscle-derived TRAIL negatively regulates myogenic differentiation. Exp Cell Res Jul 6 doi: 10.1016/j.yexcr.2020.112165. |
2020 |
Cell signaling |
|
| Kim DH, et al. (2020) TGF-β1-mediated Repression of SLC7A11 Drives Vulnerability to GPX4 Inhibition in Hepatocellular Carcinoma Cells. Cell Death Dis 11(5):406. |
2020 |
Cancer |
Liver |
| Kim HY, et al. (2020) Epidermal growth factor (EGF)-based activatable probe for predicting therapeutic outcome of an EGF-based doxorubicin prodrug. J Control Release Aug 28 doi: 10.1016/j.jconrel.2020.08.046. |
2020 |
Drug mechanism |
|
| Kim HY, et al. (2020) Protective Effect of Vitis labrusca Leaves Extract on Cardiovascular Dysfunction through HMGB1-TLR4-NFκB Signaling in Spontaneously Hypertensive Rats. |
2020 |
Other |
|
| Kim J, et al. (2020) Gene expression amplification by nuclear speckle association. J Cell Bio 219:e201904046. |
2020 |
Other |
|
| Kim J, et al. (2020) Lung-targeted Delivery of TGF-β Antisense Oligonucleotides to Treat Pulmonary Fibrosis. J Control Release 322:108−121. |
2020 |
Method development |
|
| Kim JJ, et al. (2020) Overexpression of a proton pumping gene OVP1 enhances salt stress tolerance, root growth and biomass yield by regulating ion balance in rice (Oryza sativa L.). Environ Exp Bot 175:104033. |
2020 |
Plant sciences |
|
| Kim JM, et al. (2020) Anti-Amnesic Effect of Walnut via the Regulation of BBB Function and Neuro-Inflammation in Aβ1-42-Induced Mice. Antioxidants (Basel) 9(10):E976. |
2020 |
Neurobiology |
|
| Kim JM, et al. (2020) Matcha Improves Metabolic Imbalance-Induced Cognitive Dysfunction. Oxid Med Cell Longev 2020: 8882763. |
2020 |
Other |
|
| Kim JY, et al. (2020) Kahweol Ameliorates Cisplatin-Induced Acute Kidney Injury through Pleiotropic Effects in Mice. Biomedicines 8(12):E572. |
2020 |
Cancer studies |
General |
| Knorr DY, et al. (2020) Acetylcholinesterase promotes apoptosis in insect neurons. Apoptosis Aug 5 doi: 10.1007/s10495-020-01630-4. |
2020 |
Neurobiology |
|
| Kocsmár É, et al. (2020) Cross-testing of major molecular markers indicates distinct pathways of tumorigenesis in gastric adenocarcinomas and synchronous gastrointestinal stromal tumors. Sci Rep 10(1):22212. |
2020 |
Cancer studies |
Gastric cancer |
| Kong Q, et al. (2020) Identification of AflR Binding Sites in the Genome of Aspergillus Flavus by ChIP-Seq. J Fungi (Basel) 6(2):E52. |
2020 |
Other |
|
| Kumar A, et al. (2020) Toll‐like receptor 2 (TLR2) engages endoplasmic reticulum stress sensor IRE1α to regulate retinal innate responses in Staphylococcus aureus endophthalmitis. FASEB J Aug 19 doi: 10.1096/fj.202001393R. |
2020 |
Cell signaling |
|
| Kumari A, et al. (2020) Structural insights into actin filament recognition by commonly used cellular actin markers. EMBO J 39(14):e104006. |
2020 |
Other |
|
| Lapitz A, et al. (2020) Patients With Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis. Cells 9(3):721. |
2020 |
Disease study: Biomarker research |
|
| Lata E, et al. (2020) Thin-layer chromatographic quantification of magnolol and honokiol in dietary supplements and selected biological properties of these preparations. J Chromatogr A 1625: 461230. |
2020 |
Other |
|
| Lee EH, et al. (2020) Knockdown of TRPM7 prevents tumor growth, migration, and invasion through the Src, Akt, and JNK pathway in bladder cancer. BMC Urol 20(1):145. |
2020 |
Cell signaling |
|
| Lee J, et al. (2020) Androsamide, a Cyclic Tetrapeptide from a Marine Nocardiopsis sp., Suppresses Motility of Colorectal Cancer Cells. J Nat Prod Sep 28 doi: 10.1021/acs.jnatprod.0c00815. |
2020 |
Cancer studies |
Colorectal cancer |
| Lee MH, et al. (2020) Licorice extract suppresses adipogenesis through regulation of mitotic clonal expansion and adenosine monophosphate‐activated protein kinase in 3T3‐L1 cells. |
2020 |
Other |
|
| Lee R, et al. (2020) Effects of Gintonin-Enriched Fraction on Hippocampal Gene Expressions. Integr Med Res July 15 doi: 10.1016/j.imr.2020.100475. |
2020 |
Method development |
|
| Lee SM, et al. (2020) FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging. Nat Commun 11(1):5661. |
2020 |
Other |
|
| Li D, et al. (2020) Synergism of cisplatin-oleanolic acid co-loaded hybrid nanoparticles on gastric carcinoma cells for enhanced apoptosis and reversed multidrug resistance. Drug Deliv 27(1):191−199. |
2020 |
Cancer |
Gastric |
| Li G, et al. (2020) Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome. Int J Mol Sci 21(7):2634. |
2020 |
Other |
|
| Li J, et al. (2020) CircRNA TADA2A relieves idiopathic pulmonary fibrosis by inhibiting proliferation and activation of fibroblasts. |
2020 |
Other |
|
| Li P, et al. (2020) LINC00271 inhibits epithelial-mesenchymal transition of papillary thyroid cancer cells by downregulating trefoil factor 3 expression. Aging Pathobiology and Therapeutics 2(2):78–85. |
2020 |
Cancer studies |
General |
| Li Y, et al. (2020) microRNA-103a-3p confers protection against lipopolysaccharide-induced sepsis and consequent multiple organ dysfunction syndrome by targeting HMGB1. Infect Genet Evol Dec 14 doi: 10.1016/j.meegid.2020.104681 doi: 10.1016/j.meegid.2020.104681. |
2020 |
Other |
|
| Liang L, et al. (2020) miR-4429 Regulates the Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Cervical Cancer by Targeting FOXM1. Cancer Manag Res 12:5301–5312. |
2020 |
Cancer studies |
Cervical cancer |
| Lim D, et al. (2020) Targeted Delivery of the Mitochondrial Target Domain of Noxa to Tumor Tissue via Synthetic Secretion System in E. coli. Front Bioeng Biotechnol |
2020 |
Drug mechanism |
|
| Lin YM, et al. (2020) Nerolidol improves cardiac function in spontaneously hypertensive rats by inhibiting Cardiac Inflammation and remodelling associated TLR4/NF-κB signaling cascade. Food Chem Toxicol Nov 17 doi: 10.1016/j.fct.2020.111837. |
2020 |
Cell signaling |
|
| Linke V, et al. (2020) A large-scale genome–lipid association map guides lipid identification. Nat Metab Sep 21 doi: 10.1038/s42255-020-00278-3. |
2020 |
Other |
|
| Liu EA, et al. (2020) Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain. JCI Insight Sep 15 doi: 10.1172/jci.insight.136676. |
2020 |
Neurobiology |
|
| Liu R, et al. (2020) GPR120 Agonist GW9508 Ameliorated Cellular Senescence Induced by ox-LDL. ACS Omega 5:32195−32202. |
2020 |
Cell signaling |
|
| Liu Y, et al. (2020) Ginsenoside Rh2 inhibits HeLa cell energy metabolism and induces apoptosis by upregulating voltage‑dependent anion channel 1. Int J Mol Med 46(5):1695–1706. |
2020 |
Other |
|
| Lu CH, et al. (2020) Fic Proteins Inhibit the Activity of Topoisomerase IV by AMPylation in Diverse Bacteria. Front Microbiol August 26 doi: 10.3389/fmicb.2020.02084. |
2020 |
Microorganisms and model organisms |
|
| Lu T, et al. (2020 Up-regulation of hypoxia-inducible factor antisense as a novel approach to treat ovarian cancer. Theranostics 10(15):6959–6976. |
2020 |
Cancer studies |
Ovarian |
| Luo L, et al. (2020) Sestrin 2 Attenuates Sepsis-Associated Encephalopathy Through the Promotion of Autophagy in Hippocampal Neurons. J Cell Mol Med doi:10.1111/jcmm.15313. |
2020 |
Neurobiology |
|
| Ma B, et al. (2020) Differential Histone Distribution Patterns in Induced Asymmetrically Dividing Mouse Embryonic Stem Cells. Cell Rep 32(6):108003. |
2020 |
Stem cells |
|
| Mariano Jr EB, et al. (2020) Relationship of Fibronectic 1 (FN1) to the Extended Semen Shelf Life of Duson and Phillipine Native Boar-quezon at Different Storage Temperatures. Philipp J Vet Anim Sci 46(1):12–19. |
2020 |
Other |
|
| Marín-Ramos NI, et al. (2020) MiR-18a inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations. Circ Res Aug 5 doi: 10.1161/CIRCRESAHA.119.316317. |
2020 |
Neurobiology |
|
| Martin-Perez M, et al. (2020) PKC downregulation upon rapamycin treatment attenuates mitochondrial disease. Nat Metab 2(12):1472-1481 |
2020 |
Mitochondrial studies |
|
| McClellan EB, et al. (2020) L‐citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs. Pediatr Pulmonol Jul 14 doi: 10.1002/ppul.24960. |
2020 |
Cell signaling |
|
| Merlo, S, et al. (2020) SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence. Biomolecules 10(3):364. |
2020 |
Cell signaling |
|
| Miteva K, et al. (2020) Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression. Sci Rep 10(1):5791. |
2020 |
Other |
|
| Morel G, et al. (2020) Mandibular‐Pelvic‐Patellar syndrome (MPP) is a novel PITX1‐related disorder due to alteration of PITX1 transactivation ability. Hum Mutat Jun 29 doi: 10.1002/humu.24070. |
2020 |
Other |
|
| Móricz AM, et al. (2020) Bioactive clerodane diterpenes of giant goldenrod (Solidago gigantea Ait.) root extract. J Chromatogr A Nov 19 doi: 10.1016/j.chroma.2020.461727. |
2020 |
Plant sciences |
|
| Móricz ÁM, et al. (2020) High-performance thin-layer chromatography hyphenated to high-performance liquid chromatography-diode array detection-mass spectrometry for characterization of coeluting isomers. Talanta 219: 121306. |
2020 |
Method development |
|
| Morotti A, et al. (2020) The oncosuppressors MEN1 and CDC73 are involved in lncRNAs deregulation in human parathyroid tumors. J Bone Miner Res Aug 11 doi: 10.1002/jbmr.4154. |
2020 |
Cancer studies |
General |
| Mu J, et al. (2020) Effect of Lactobacillus plantarum KFY02 isolated from naturally fermented yogurt on the weight loss in mice with high-fat diet-induced obesity via PPAR-α/γ signaling pathway. J Funct Foods 75 104264. |
2020 |
Cell signaling |
|
| Mu J, et al. (2020) Lactobacillus fermentum CQPC06 in Naturally Fermented Pickles Prevents Non-alcoholic Fatty Liver Disease by Stabilizing the Gut-liver Axis in Mice. Food Funct Sep 18 doi: 10.1039/d0fo01823f. |
2020 |
Microorganisms and model organisms |
|
| Nakamura-Bencomo s, et al. (2020) Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities. Invest New Drugs Oct 16 doi: 10.1007/s10637-020-01020-2. |
2020 |
Cancer studies |
General |
| Neff AM, et al. (2020) Insulin Signaling Via Progesterone-Regulated Insulin Receptor Substrate 2 is Critical for Human Uterine Decidualization. Endocrinology 161:bqz021. |
2020 |
Cell signaling |
|
| Nolte WW, et al. (2020) Screening trimethoprim primary metabolites for covalent binding to albumin. Med Chem Res 29:1238–1246. |
2020 |
Other |
|
| Ogawa M, et al. (2020) Contribution of Extracellular O-GlcNAc to the Stability of Folded Epidermal Growth Factor-Like Domains and Notch1 Trafficking. Biochem Biophys Res Commun Mar 19 doi: 10.1016/j.bbrc.2020.03.066. |
2020 |
Cell signaling |
|
| Othmène YB, et al. (2020) Oxidative stress, DNA damage and apoptosis induced by tebuconazole in kidney of male Wistar rats. Chem Biol Interact Jul 28 doi: 10.1016/j.cbi.2020.109114. |
2020 |
Cell signaling |
|
| Othmène YB, et al. (2020) Tebuconazole induces ROS-dependent cardiac cell toxicity by activating DNA damage and mitochondrial apoptotic pathway. Ecotoxicol Environ Saf 204:111040. |
2020 |
Cell signaling |
|
| Owiredu S, et al. (2020) In vitro Comparison of Hydroxocobalamin (B12a) and the Mitochondrial Directed therapy by a Succinate Prodrug in a Cellular Model of Cyanide Poisoning. Toxicol Rep 7:1263–1271. |
2020 |
Mitochondrial studies |
|
| Özliseli E, et al. (2020) Rational evaluation of human serum albumin coated mesoporous silica nanoparticles for xenogenic-free stem cell therapies. Colloids Surf A Physico Chem Eng Asp 600:124945. |
2020 |
Method development |
|
| Paldino E, et al. (2020) Modulation of Inflammasome and Pyroptosis by Olaparib, a PARP-1 Inhibitor, in the R6/2 Mouse Model of Huntington's Disease. Cells 9(10):E2286. |
2020 |
Neurobiology |
|
| Paldino E, et al. (2020) Pyroptotic cell death in the R6/2 mouse model of Huntington's disease: new insight on the inflammasome. Cell Death Discov 6:69. |
2020 |
Neurobiology |
|
| Pan H, et al. (2020) Lactobacillus plantarum KFY02 enhances the prevention of CCl4-induced liver injury by transforming geniposide into genipin to increase the antioxidant capacity of mice. J Funct Foods 73:104128. |
2020 |
Microorganisms and model organisms |
|
| Pan H, et al. (2020) Mesenchymal Stem Cells Combined With Tissue Fusion Technology Promoted Wound Healing in Porcine Bowel Anastomosis. Stem Cells Int 2020:5142797. |
2020 |
Stem cells |
|
| Pan H, et al. (2020) Mesenchymal Stem Cells Combined with Tissue Fusion Technology Promoted Wound Healing in Porcine Bowel Anastomosis. Stem Cells Int Feb 12 doi: 10.1155/2020/5142797. |
2020 |
Other |
|
| Paradzik M, et al. (2020) KANK2 Links αVβ5 Focal Adhesions to Microtubules and Regulates Sensitivity to Microtubule Poisons and Cell Migration. Front Cell Dev Biol 8:125. |
2020 |
Other |
|
| Park M, et al. (2020) Anti-FLT3 Nanoparticles for Acute Myeloid Leukemia: Preclinical Pharmacology and Pharmacokinetics. J Control Release 324:317-329. |
2020 |
Cancer |
General |
| Pellavio G, et al. (2020) HPV Infection Affects Human Sperm Functionality by Inhibition of Aquaporin-8. Cells 9(5):E1241. |
2020 |
Other |
|
| Pelletier J, et al. (2020) Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage. EMBO J 39(13):e103838. |
2020 |
Other |
|
| Peng KC, et al. (2020) Expression of L-amino acid oxidase of Trichoderma harzianum in tobacco confers resistance to Sclerotinia sclerotiorum and Botrytis cinereal. Plant Sci Nov 24 doi: 10.1016/j.plantsci.2020.110772. |
2020 |
Plant sciences |
|
| Pires Da Silva J, et al. (2020) SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy. Cells 9(2):426. |
2020 |
Cell signaling |
|
| Plotnikov A, et al. (2020) PRMT1 inhibition induces differentiation of colon cancer cells. Sci Rep 10(1):20030. |
2020 |
Cancer studies |
Colon cancer |
| Prieto-Garcia C, et al. (2020) Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells. MBO Mol Med 12(4):e11101. |
2020 |
Cancer studies |
Squamous cell carcinoma |
| Protective effects of polymethoxyflavone-rich cold-pressed orange peel oil against ultraviolet B-induced photoaging on mouse skin. J Funct Foods 67:103834. |
2020 |
Other |
|
| Qian B, et al. (2020) Ameliorative Effect of Sinapic Acid on Dextran Sodium Sulfate-(DSS-) Induced Ulcerative Colitis in Kunming (KM) Mice. Oxid Med Cell Longev 2020: 8393504. |
2020 |
Other |
|
| Qu W, Li L. (2020) Loss of TREM2 confers resilience to synaptic and cognitive impairment in aged mice. J Neurosci Nov 2 doi: 10.1523/JNEUROSCI.2193-20.2020. |
2020 |
Neurobiology |
|
| Raducanu V, et al. (2020) Simplified detection of polyhistidine-tagged proteins in gels and membranes using a UV-excitable dye and a multiple chelator head pair. J Biol Chem Jul 9 doi: 10.1074/jbc.RA120.014132. |
2020 |
Method development |
|
| Raducanu VS, et al. (2020) Two Chromatographic Schemes for Protein Purification Involving the Biotin/Avidin Interaction Under Native Conditions. J Chromatography A Mar 17 doi: 10.1016/j.chroma.2020.461051. |
2020 |
Method development |
|
| Reichermeier KM, et al. (2020) PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network. Mol Cell 77:1–15. |
2020 |
Cell signaling |
|
| Roman B, et al. (2020) Nuclear-mitochondrial Communication Involving miR-181c Plays an Important Role in Cardiac Dysfunction During Obesity. J Mol Cell Cardiol 144:87−96. |
2020 |
Mitochondrial studies |
|
| Sadiki A, et al. (2020) Site-specific Bioconjugation and Convergent Click Chemistry Enhances Antibody-Chromophore Conjugate Binding Efficiency. Photochem Photobiol Feb 21 doi: 10.1111/php.13231. |
2020 |
Method development |
|
| Salgado-Lora MG, et al. (2020) Prolactin and Estradiol are Epigenetic Modulators in Bovine Mammary Epithelial Cells during Staphylococcus aureus Infection. Pathogens 9(7):E520. |
2020 |
Other |
|
| Samanas NB, et al. (2020) Defective Nucleotide-Dependent Assembly and Membrane Fusion in Mfn2 CMT2A Variants Improved by Bax. Life Sci Alliance 3(5):e201900527. |
2020 |
Mitochondrial studies |
|
| Sciamanna G, et al. (2020) Optogenetic Activation of Striatopallidal Neurons Reveals Altered HCN Gating in DYT1 Dystonia. Cell Rep 31(7):107644. |
2020 |
Neurobiology |
|
| Seltzer J, et al. (2020) Interleukin-1 Receptor Associated Kinase (IRAK) Signaling in Kaposi Sarcoma-associated Herpesvirus (KSHV) Induced Primary Effusion Lymphoma. J Virol. JVI.02123-19. |
2020 |
Cancer |
Karposi sarcoma |
| SH Siddiqui SH, et al. (2020) Direct exposure to mild heat stress stimulates cell viability and heat shock protein expression in primary cultured broiler fibroblasts. Cell Stress Chaperones Jul 22 doi: 10.1007/s12192-020-01140-x. |
2020 |
General |
|
| Shahrouzi P, et al. (2020) Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis. Cancers (Basel) 12(9):E2593. |
2020 |
Cancer studies: General |
|
| Shanmugapriya K, et al. (2020) Cellulose nanocrystals/nanofibrils loaded astaxanthin nanoemulsion for the induction of apoptosis via ROS-dependent mitochondrial dysfunction in cancer cells under photobiomodulation. Int J Biol Macromol 149:165−177. |
2020 |
Cancer |
Skin |
| Shanmugapriya K, et al. (2020) Epidermal Growth Factor Receptor Conjugated Fucoidan/Alginates Loaded Hydrogel for Activating EGFR/AKT Signaling Pathways in Colon Cancer Cells During Targeted Photodynamic Therapy. Int J Biol Macromol May 6 doi: 10.1016/j.ijbiomac.2020.05.008. |
2020 |
Cancer |
Colorectal |
| Shanmugapriya K, et al. (2020) Fucoidan-loaded hydrogels facilitates wound healing using photodynamic therapy by in vitro and in vivo evaluation. Carbohydr Polym 247:116624. |
2020 |
Drug mechanism |
|
| Shi H, et al. (2020) Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease. Acta Neuropathol Commun 8(1):202. |
2020 |
Neurobiology |
|
| Shin CH, et al. (2020) Exosomal miRNA-19a and miRNA-614 Induced by Air Pollutants Promote Proinflammatory M1 Macrophage Polarization via Regulation of RORα Expression in Human Respiratory Mucosal Microenvironment. J Immunol Oct 28 doi: 10.4049/jimmunol.2000456. |
2020 |
Other |
|
| Siddiqui SH, et al. (2020) Chronic heat stress regulates the relation between heat shock protein and immunity in broiler small intestine. Sci Rep 10(1):18872. |
2020 |
Other |
|
| Siregar, AS, et al. (2020) Dipeptide YA is Responsible for the Positive Effect of Oyster Hydrolysates on Alcohol Metabolism in Single Ethanol Binge Rodent Models. Mar Drugs 18(10):E512. |
2020 |
Other |
|
| Somayajulu M, et al. (2020) Airborne Particulates Affect Corneal Homeostasis and Immunity. Invest Ophthalmol Vis Sci 61(4):23. |
2020 |
Other |
|
| Soncini D, et al. (2020) Amino acid depletion triggered by ʟ-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death. Blood Adv 4(18):4312–4326 |
2020 |
Mitochondrial studies |
|
| Srivastava T, et al. (2020) Upregulated proteoglycan-related signaling pathways in fluid flow shear stress-treated podocytes. Am J Physiol Renal Physiol Jul 6 doi: 10.1152/ajprenal.00183.2020. |
2020 |
Other |
|
| Stieg DC, et al. (2020) The extent of cyclin C promoter occupancy directs changes in stress-dependent transcription. J Biol Chem Sep 15 doi: 10.1074/jbc.RA120.015215. |
2020 |
Other |
|
| Sun G, et al. (2020) Phoenixin-20 suppresses lipopolysaccharide-induced inflammation in dental pulp cells. Chem Biol Interact 318:108971. |
2020 |
Cell signaling |
|
| Sun Y, et al. (2020) Therapeutic effect and mechanisms of the novel monosulfactam 0073. Antimicrob Agents Chemother Jul 27 doi: 10.1128/AAC.00529-20. |
2020 |
Microorganisms and model organisms |
|
| Tayebi M, et al. (2020) Exosome Purification and Analysis Using a Facile Microfluidic Hydrodynamic Trapping Device. Anal Chem Jul 17 doi: 10.1021/acs.analchem.0c02006. |
2020 |
Method development |
|
| Teng Y, et al. (2020) Lactobacillus plantarumLP104 ameliorates hyperlipidemia induced by AMPK pathways in C57BL/6N mice fed high-fat diet. J Functional Foods 64:103665. |
2020 |
Microorganisms and model organisms |
|
| Thibeault PE, et al. (2020) Role of the Helix-8 and C-Terminal Tail in Regulating Proteinase Activated Receptor 2 Signaling. ACS Pharmacol Transl Sci Aug 10 doi:10.1021/acsptsci.0c00039. |
2020 |
Cell signaling |
|
| Thongnak L, et al. (2020) Mitigation of renal inflammation and endoplasmic reticulum stress by vildagliptin and statins in high-fat high-fructose diet-induced insulin resistance and renal injury in rats. Biochim Biophys Acta Mol Cell Biol Lipids 1865(9):158755. |
2020 |
Other |
|
| Tu MM, et la. (2020) Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy. Commun Biol 3(1):720. |
2020 |
Cancer studies |
General |
| Vargas AM, et al. (2020) Methamphetamine Alters the TLR4 Signaling Pathway, NF-κB Activation, and Pro-Inflammatory Cytokine Production in LPS-challenged NR-9460 Microglia-Like Cells. Mol Immunol 121:159−166. |
2020 |
Cell signaling |
|
| Verma DK, et al. (2020) The SUMO conjugase Ubc9 protects Dopaminergic cells from cytotoxicity and enhances the stability of α-synuclein in Parkinson's disease models. |
2020 |
Neurobiology |
|
| Wang H, et al. (2020) DPP-4 Inhibitor Linagliptin Ameliorates Oxidized LDL-Induced THP-1 Macrophage Foam Cell Formation and Inflammation. Drug Des Devel Ther 2020(14):3929–3940. |
2020 |
Other |
|
| Wang H, et al. (2020) Long non-coding RNA LICPAR regulates atrial fibrosis via TGF-β/Smad pathway in atrial fibrillation. Tissue Cell 67:101440. |
2020 |
Cell signaling |
|
| Wang Y, et al. (2020) Pediococcus pentosaceus PP04 Ameliorates High-Fat Diet-Induced Hyperlipidemia by Regulating Lipid Metabolism in C57BL/6N Mice. J Agric Food Chem Dec 10 doi: 10.1021/acs.jafc.0c05060. |
2020 |
Other |
|
| Wang Y, et al. (2020) Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway. Life Sci 259:118284 |
2020 |
Cell signaling |
|
| Wang Y, et al. (2020) TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition. Cell Death Dis 11(6):482. |
2020 |
Stem cells |
|
| Wang Z, et al. (2020) Kaempferol Ameliorates Cisplatin Induced Nephrotoxicity by Modulating Oxidative Stress, Inflammation and Apoptosis via ERK and NF-κB Pathways. AMB Express 10(1):58. |
2020 |
Cell signaling |
|
| Widyastuti HP, et al. (2020) Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis. BMC Med Genet 21(1):152. |
2020 |
Disease study: Biomarker research |
|
| Widyastuti HP, et al. (2020) Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis. BMC Med Genet 21(1):152. |
2020 |
Disease study: Biomarker research |
|
| Wössner N, et al. (2020) Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD + Dependent Lysine Deacetylases. Front Oncol 10:657. |
2020 |
Cancer |
General |
| Wu A, et al. (2020) DNMT1 Promotes Cell Proliferation via Methylating hMLH1 and hMSH2 Promoters in EGFR-mutated Non-Small Cell Lung Cancer. J Biochem Mar 25 doi: 10.1093/jb/mvaa034. |
2020 |
Cancer |
Lung |
| Wu C, et al. (2020) Evaluation of the Post-Treatment Anti-Inflammatory Capacity of Osteoarthritic Chondrocytes: An in vitro Study Using Baicalein. Regen Ther14:177−183. |
2020 |
Cell signaling |
|
| Xiao P, et al. (2020) LncRNA NEAT1 regulates chondrocyte proliferation and apoptosis via targeting miR-543/PLA2G4A axis. |
2020 |
Other |
|
| Xin L, et al. (2020) Methionine represses the autophagy of gastric cancer stem cells via promoting the methylation and phosphorylation of RAB37. Cell Cycle Sep 14 doi: 10.1080/15384101.2020.1814044. |
2020 |
Cancer studies: Gastric cancer |
|
| Xin S, Ye L. (2020) Knockdown of long non‑coding RNA CCAT2 suppresses the progression of thyroid cancer by inhibiting the Wnt/β‑catenin pathway. Int J Mol Med Sept 4 doi: 10.3892/ijmm.2020.4761. |
2020 |
Cancer studies |
General |
| Xin X, et al. (2020) Redox-responsive nanoplatform for codelivery of miR-519c and gemcitabine for pancreatic cancer therapy. Sci Adv 6(46):eabd6764. |
2020 |
Cancer studies |
Pancreatic cancer |
| Xu WF, et al. (2020) Gasdermin E-derived caspase-3 Inhibitors Effectively Protect Mice From Acute Hepatic Failure. Acta Pharmacol Sin May 26 doi: 10.1038/s41401-020-0434-2. |
2020 |
Drug mechanism |
|
| Xue W, et al. (2020) Rotenone Restrains the Proliferation, Motility and Epithelial-Mesenchymal Transition of Colon Cancer Cells and the Tumourigenesis in Nude Mice via PI3K/AKT Pathway. Clin Exp Pharmacol Physiol Apr 13 doi: 10.1111/1440-1681.13320. |
2020 |
Cancer |
Colorectal |
| Yang M, et al. (2020) Preventive effect of lemon seed flavonoids on carbon tetrachloride-induced liver injury in mice. RSC Adv 10:12800−128009. |
2020 |
Other |
|
| Yang X, et al. (2020) Inhibition of ITGB1 enhance the anti-tumor effect of cetuximab in colorectal cancer cell. Medicine (Baltimore) 99(27):e20944. |
2020 |
Cancer studies |
Colorectal cancer |
| Yang Y, et al. (2020) Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents. Molecules 25(3):645. |
2020 |
Cancer |
General |
| Yao Q, et al. (2020) Unsaturated fatty acid-enriched extract from Hippophae rhamnoides seed reduces skin dryness through up-regulating aquaporins 3 and hyaluronan synthetases 2 expressions. J Cosmet Dermatol Jul 8 doi: 10.1111/jocd.13482 |
2020 |
Other |
|
| Yee YH, et al. (2020) Sustained IKKβ Phosphorylation and NF-κB Activation by Superoxide-induced Peroxynitrite-mediated Nitrotyrosine Modification of B56γ3 and PP2A Inactivation. Redox Biol Dec 8 doi: 10.1016/j.redox.2020.101834. |
2020 |
Cell signaling |
|
| Yi R, et al. (2020) Intervention effects of lotus leaf flavonoids on gastric mucosal lesions in mice infected with Helicobacter pylori. RSC Adv 10:23510. |
2020 |
Plant sciences |
|
| Yoon JJ, et al. (2020) Betulinic Acid Protects DOX-Triggered Cardiomyocyte Hypertrophy Response through the GATA-4/Calcineurin/NFAT Pathway. Molecules 26(1):E53. |
2020 |
Cell signaling |
|
| Zamorano-Leon JJ, et al. (2020) Factor Xa Inhibition by Rivaroxaban Modified Mitochondrial-Associated Proteins in Human Abdominal Aortic Aneurysms. Ann Vasc Surg Mar 12 doi: 10.1016/j.avsg.2020.02.005. |
2020 |
Other |
|
| Zanin S, et al. (2020) Intracellular protein kinase CK2 inhibition by ferulic acid-based trimodal nanodevice. Int J Biol Macromol 165(Pt A):701–712. |
2020 |
Other |
|
| Zeng N, et al. (2020) LEFTY2/endometrial Bleeding-Associated Factor Up-Regulates Na+ Coupled Glucose Transporter SGLT1 Expression and Glycogen Accumulation in Endometrial Cancer Cells. PLoS One 15(4):e0230044. |
2020 |
Cancer |
Endometrial |
| Zeng Y, et al. (2020) The GPR55 Antagonist CID16020046 Mitigates Advanced Glycation End Products (AGEs)- Induced Chondrocyte Activation. Chem Biol Interact 325:109088. |
2020 |
Cell signaling |
|
| Zeng ZL, et al. (2020) Highly Expressed lncRNA FOXD3-AS1 Promotes Non-Small Cell Lung Cancer Progression via Regulating miR-127-3p/mediator Complex Subunit 28 Axis. Euro Rev Med Pharmacol Sci 24: 2525−2538. |
2020 |
Cancer |
Lung |
| Zhang H, et al. (2020) Silencing TTTY15 mitigates hypoxia-induced mitochondrial energy metabolism dysfunction and cardiomyocytes apoptosis via TTTY15/let-7i-5p and TLR3/NF-κB pathways. |
2020 |
Cell signaling |
|
| Zhang H, et al. (2020) Structural, physicochemical and functional properties of Semen Ziziphi Spinosae protein. RSC Adv 10:29555. |
2020 |
Plant sciences |
|
| Zhang J, et al. (2020) Identifying Mutation Hotspots Reveals Pathogenetic Mechanisms of KCNQ2 Epileptic Encephalopathy. Sci Rep 10(1):4756. |
2020 |
Neurobiology |
|
| Zhang W, et al. (2020) LncRNA DANCR regulates osteosarcoma migration and invasion by targeting miR-149/MSI2 axis. Eur Rev Med Pharmacol Sci 24(12):6551–6560. |
2020 |
Cancer studies |
General |
| Zhao L, et al. (2020) Puerarin alleviates coronary heart disease via suppressing inflammation in a rat model. Gene 771:145354. |
2020 |
Cell signaling |
|
| Zhao Q, et al. (2020) Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output. Cell Sep 5 doi: 10.1016/j.cell.2020.08.009. |
2020 |
Mitochondrial studies |
|
| Zhao T, et al. (2020) PD‑L1 expression increased by IFN‑γ via JAK2‑STAT1 signaling and predicts a poor survival in colorectal cancer. Oncol Lett May 20 doi.org/10.3892/ol.2020.11647. |
2020 |
Cancer |
Colorectal |
| Zimmer A, et al. (2020) The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity. Eur J Pharmacol Nov 5 doi: 10.1016/j.ejphar.2020.173699. |
2020 |
Other |
|
| Arreal L, et al. (2019) Targeting PML in triple negative breast cancer elicits growth suppression and senescence. Cell Death Differ Oct 1 doi: 10.1038/s41418-019-0407-5. |
2019 |
Cancer |
Breast |
| Bellot GL, et al. (2019) MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management. Redox Biol 20:307−320. |
2019 |
Drug mechanism |
|
| Bhatt T, et al. (2019) Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8. Cell Rep 29(9):2546−2555.e4. |
2019 |
Cell signaling |
|
| Bloomfield M, Louie MC (2019) Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα. Sci Rep 9(1):12135. |
2019 |
Cancer |
Breast |
| Chi X, et al. (2019) A system for site-specific integration of transgenes in mammalian cells. PLoS One 14(7):e0219842. |
2019 |
Method development |
|
| Courtney AH, et al.(2019) CD45 functions as a signaling gatekeeper in T cells. Sci Signal Oct 22 doi: 10.1126/scisignal.aaw8151. |
2019 |
Cell signaling |
|
| Depledge DP, et al. (2019) Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen. Nat Commun 10(1):754. |
2019 |
Other |
|
| Dong Q, et al. (2019) A signal-flexible gene diagnostic strategy coupling loop-mediated isothermal amplification with hybridization chain reaction. Anal Chim Acta 1079:171−179. |
2019 |
Method development |
|
| Durante L, et al. (2019) Characterization of the GPR1/FUN34/YaaH protein family in the green microalga Chlamydomonas suggests their role as intracellular membrane acetate channels. Plant Direct 3(6):e00148. |
2019 |
Plant sciences |
|
| Englehart EA, Hoppins S. (2019) A catalytic domain variant of Mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion. J Biol Chem April 1 doi: 10.1074/jbc.RA118.006347. |
2019 |
Mitochondrial studies |
|
| Funabara D, et al. (2019) Phosphorylation Properties of the N-Terminal Region of Twitchin from Molluscan Catch Muscle. American Journal of Molecular Biology 9:110−120. |
2019 |
Cell signaling |
|
| Gansukh E, et al. (2019) Chemopreventive Effect of β-Cryptoxanthin on Human Cervical Carcinoma (HeLa) Cells Is Modulated through Oxidative Stress-Induced Apoptosis. Antioxidants (Basel) 9(1):28. |
2019 |
Drug mechanism |
|
| Gao M, et al. (2019) Identification of a Cry1Fa binding site of cadherin in Plutella xylostella through fragment exchanging and molecular docking methods. Int J Biol Macromol 146:62−69. |
2019 |
Method development |
|
| Groveman BR, et al. (2019) Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids. Acta Neuropathol Commun 7(1):90. |
2019 |
Neurobiology |
|
| Hohl A, et al. (2019) Engineering a Polyspecific Pyrrolysyl-tRNA Synthetase by a High Throughput FACS Screen. Sci Rep 9(1):11971. |
2019 |
Method development |
|
| Honda JR, et al. (2019) Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37. Am J Respir Cell Mol Biol Sep 23 doi: 10.1165/rcmb.2018-0278OC. |
2019 |
Microorganisms and model organisms |
|
| Huang M, et al. (2019) HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway. Neurotox Res Dec 20 doi: 10.1007/s12640-019-00148-1. |
2019 |
Neurobiology |
|
| Huang TL, et al. (2019) The therapeutic effect of aucubin-supplemented hyaluronic acid on interleukin-1 beta-stimulated human articular chondrocytes. Phytomedicine 53:1−8. |
2019 |
Other |
|
| Jia QL, et al. (2019) Fisetin, via CKIP-1/REGγ, limits oxidized LDL-induced lipid accumulation and senescence in RAW264.7 macrophage-derived foam cells. Eur J Pharmacol Oct 23 doi: 10.1016/j.ejphar.2019.172748. |
2019 |
Other |
|
| Kang D, et al. (2019) Heat Treatment at an Early Age Has Effects on the Resistance to Chronic Heat Stress on Broilers. Animals (Basel) 9(12):1022. |
2019 |
Other |
|
| Kang JY, et al. (2019) 4,5-dicaffeyolquinic acid improves high-fat diet-induced cognitive dysfunction through the regulation of insulin degrading enzyme. J Food Biochem 43(7):e12855. |
2019 |
Neurobiology |
|
| Karaszi K, et al. (2019) Increased placental expression of placental protein 5 (PP5) / tissue factor pathway inhibitor-2 (TFPI-2) in women with preeclampsia and HELLP syndrome: Relevance to impaired trophoblast invasion? Placenta 76:30−39. |
2019 |
Disease study: Biomarker research |
|
| Kim DI, et al. (2019) Comparison of asthma phenotypes in OVA-induced mice challenged via inhaled and intranasal routes. BMC Pulm Med 19(1):241. |
2019 |
Other |
|
| Lee BR, et al. (2019) Distinct role of Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) in inhibiting cargo-loading and release of extracellular vesicles. Sci Rep 9(1):20049. |
2019 |
Cell signaling |
|
| Lee JY, et al. (2019) Red Blood Cell Membrane Bioengineered Zr-89 Labelled Hollow Mesoporous Silica Nanosphere for Overcoming Phagocytosis. Sci Rep 9(1):7419. |
2019 |
Cancer |
General |
| Liu B, et al. (2019) Effects of Lactobacillus plantarum CQPC01-fermented soybean milk on activated carbon-induced constipation through its antioxidant activity in mice. Food Sci Nutr 7(6):2068−2082. |
2019 |
Microorganisms and model organisms |
|
| Liu L, et al. (2019) Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half-life. Alzheimers Dement (9):1183−1194. |
2019 |
Neurobiology |
|
| Moricz AM, et al. (2019) Distinction and valorization of 30 root extracts of five goldenrod (Solidago) species. J Chromatography A Oct 7 doi: 10.1016/j.chroma.2019.460602. |
2019 |
Plant sciences |
|
| Napso T, et al. (2019) Advanced maternal age compromises fetal growth and induces sex-specific changes in placental phenotype in rats. Sci Rep 9:16916. |
2019 |
Other |
|
| O'Brien CE, et al. (2019) Hypoxia-Ischemia and Hypothermia Independently and Interactively Affect Neuronal Pathology in Neonatal Piglets with Short-Term Recovery. Dev Neurosci 41(1-2):17−33. |
2019 |
Neurobiology |
|
| Oh TJ, et al. (2019) TBX3 represses TBX2 under the control of the PRC2 complex in skeletal muscle and rhabdomyosarcoma. Oncogenesis April 12 doi: 10.1038/s41389-019-0137-z. |
2019 |
Cancer |
General |
| Oliveira-Mateos C, et al. (2019) The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition. Nat Commun 10(1):3979. |
2019 |
Cancer |
General |
| Orlomoski R, et al. (2019) Rapid and efficient purification of Drosophila homeodomain transcription factors for biophysical characterization. Protein Expr Purif 158:9−14. |
2019 |
Method development |
|
| Park C, et al. (2019) Species-specific inhibition of antiviral protein kinase R by capripoxviruses and vaccinia virus. Ann NY Acad Sci 1438(1):18−29. |
2019 |
Microorganisms and model organisms |
|
| Park SK, et al. (2019) Fucoidan-Rich Substances from Ecklonia cava Improve Trimethyltin-Induced Cognitive Dysfunction via Down-Regulation of Amyloid β Production/Tau Hyperphosphorylation. Mar Drugs 17(10). |
2019 |
Neurobiology |
|
| Qiang C, et al. (2019) Flavonoids from Apios americana Medikus Leaves Protect RAW264.7 Cells against Inflammation via Inhibition of MAPKs, Akt-mTOR Pathways, and Nfr2 Activation. Oxid Med Cell Longev 2019:1563024. |
2019 |
Cell signaling |
|
| Qiao W, et al. (2019) A Novel Effect of Lipids Extracted from Vernix Caseosa on Regulation of Filaggrin Expression in Human Epidermal Keratinocytes. Ann Dermatol 31(6):611−620. |
2019 |
Other |
|
| Rageul J, et al. (2019) Conditional degradation of SDE2 by the Arg/N-End rule pathway regulates stress response at replication forks. Nucleic Acids Res Jan 30 ePub:gkz054 |
2019 |
Other |
|
| Schultz ML, et al. (2019) Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann-Pick diseases. BMC Med 17(1):200. |
2019 |
Neurobiology |
|
| Senthilkumar R, et al. (2019) Synthesis and Evaluation of Anisomelic acid-like Compounds for the Treatment of HPV-Mediated Carcinomas. Sci Rep 9(1):20295. |
2019 |
Drug mechanism |
|
| Shi CS, et al. (2019) ARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes. Cell Death Discov 5:101. |
2019 |
Cell signaling |
|
| Subramaniyan SA, et al.(2019) Effect of In Ovo Injection of L-Arginine in Different Chicken Embryonic Development Stages on Post-Hatchability, Immune Response, and Myo-D and Myogenin Proteins. Animals (Basel) Jun 14 doi: 10.3390/ani9060357. |
2019 |
Other |
|
| Suzuki H, et al. (2019) Generation of bicistronic reporter knockin mice for visualizing germ layers. Exp Anim 68(4):499−509. |
2019 |
Method development |
|
| Tas I, et al. (2019) Inflammatory and tumorigenic effects of environmental pollutants found in particulate matter on lung epithelial cells. Toxicol In Vitro 59:300−311. |
2019 |
Cancer |
Lung |
| Thomson BR, et al. (2019) Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma. Elife Oct 17 doi: 10.7554/eLife.48474. |
2019 |
Other |
|
| Tsai YH, et al. (2019) Effect of hesperidin on anti-inflammation and cellular antioxidant capacity in hydrogen peroxide-stimulated human articular chondrocytes. Process Biochemistry 85:175−184. |
2019 |
Other |
|
| Upadhyay K, et al. (2019) Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function. Redox Biol 28:10131. |
2019 |
Mitochondrial studies |
|
| Wang H, et al. (2019) High expression of the transcriptional coactivator TAZ is associated with a worse prognosis and affects cell proliferation in patients with medulloblastoma. Oncol Lett 18(5):5591−5599. |
2019 |
Cancer |
Brain |
| Wang P, et al. (2019) Haspin inhibition delays cell cycle progression through interphase in cancer cells. J Cell Physiol Oct 17 doi: 10.1002/jcp.29328. |
2019 |
Cancer |
General |
| Xing M, et al. (2019) Overexpression of p62/IMP2 can Promote Cell Migration in Hepatocellular Carcinoma via Activation of the Wnt/β-Catenin Pathway. Cancers (Basel) 12(1):7. |
2019 |
Cancer |
Liver |
| Xuan F, et al. (2019) Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone. Arthritis Res Ther 21:241. |
2019 |
Cell signaling |
|
| Yi R, et al. (2019) Lactobacillus plantarum CQPC02-Fermented Soybean Milk Improves Loperamide-Induced Constipation in Mice. J Med Food Oct 17 doi: 10.1089/jmf.2019.4467. |
2019 |
Microorganisms and model organisms |
|
| Zamboni C, et al. (2019) Cyclin D1 immunohistochemical expression and somatic mutations in canine oral melanoma. Vet Comp Oncol Sep 10 doi: 10.1111/vco.12539. |
2019 |
Cancer |
Skin |
| Zamorano-León JJ, et al. (2019) Effect of Pectin on the Expression of Proteins Associated with Mitochondrial Biogenesis and Cell Senescence in HT29-Human Colorectal Adenocarcinoma Cells. Prev Nutr Food Sci 24(2):187−196. |
2019 |
Cancer |
Colorectal |
| Zhang J, et al. (2019) Expression and function of Toll like receptors in peripheral blood mononuclear cells in patients with ankylosing spondylitis. Mol Med Rep 20(4):3565−3572. |
2019 |
Other |
|
| Zhao K, et al. (2019) TesG Is a type I secretion effector of Pseudomonas aeruginosa that suppresses the host immune response during chronic infection. Nat Microbiol 4(3):459−469. |
2019 |
Microorganisms and model organisms |
|
| Zhao X, et al. (2019) Preventive effect of Lactobacillus plantarum KSFY02 isolated from naturally fermented yogurt from Xinjiang, China, on d-galactose-induced oxidative aging in mice. J Dairy Sci 102(7):5899−5912. |
2019 |
Microorganisms and model organisms |
|
| Ha JS, et al. (2018) Anti-amyloidogenic properties of an ethyl acetate fraction from Actinidia arguta in Aβ1–42-induced ICR mice. Food Funct 9(6):3264−3277. |
2018 |
Neurobiology |
|
| Hirpara J, et al. (2018) Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance. Redox Biol Dec 17 ePub:101076. |
2018 |
Cancer |
General |
| Kelly SC, et al. (2018) Glucose-dependent trans-plasma membrane electron transport and p70S6k phosphorylation in skeletal muscle cells. Redox Biol Dec 12 ePub:101075. |
2018 |
Cell signaling |
|
| Kim JM, et al. (2018) Ethyl acetate fraction from persimmon (Diospyros kaki) ameliorates cerebral neuronal loss and cognitive deficit via the JNK/Akt pathway in TMT-induced mice. Int J Mol Sci 19:E1499. |
2018 |
Neurobiology |
|
| Li J, et al. (2018) Downregulation of Survivin gene expression affects Ionizing radiation resistance of human T98 glioma cells. Cell Mol Neurobiol 38:861–868 |
2018 |
Cancer |
Brain |
| Li J, et al. (2018) MicroRNA 423 promotes proliferation, migration and invasion and induces chemoresistance of endometrial cancer cells. Exp Ther Med 16(5):4213−4224. |
2018 |
Cancer |
Endometrial |
| Lin SR, Wen CF (2018) PG-priming enhances doxorubicin influx to trigger necrotic and autophagic cell death in oral squamous cell carcinoma. J Clin Med 7(10):e375. |
2018 |
Cancer |
Squamous cell carcinoma |
| Mishra R, et al. (2018) Can-miRn37a mediated suppression of ethylene response factors enhances the resistance of chilli against anthracnose pathogen Colletotrichum truncatum L. Plant Sci 267:135–147. |
2018 |
Plant sciences |
|
| Park, SB, et al. (2018) Aruncus dioicus var. kamtschaticus extract suppresses mitochondrial apoptosis induced-neurodegeneration in trimethyltin injected ICR mice. J Food Biochem 42(6):e12667. |
2018 |
Neurobiology |
|
| Qian Y, et al. (2018) Lactobacillus plantarum CQPC11 isolated from sichuan pickled cabbages antagonizes d-galactose-induced oxidation and aging in mice. Molecules 23(11):e3026. |
2018 |
Other |
|
| Ran L, et al. (2018) Humoral factors contributing to ectopic bone formation induced by medical biomaterials. J Biomater Tissue Eng 8:880–886. |
2018 |
Other |
|
| Schultz ML, et al. (2018) Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD. Nat Commun 9(1):3671. |
2018 |
Neurobiology |
|
| Sun Y, et al. (2018) BMAL1 and CLOCK proteins in regulating UVB‐induced apoptosis and DNA damage responses in human keratinocytes. J Cell Physiol 233(12):9563−9574. |
2018 |
Cell signaling |
|
| Taş I, et al. (2018) Physciosporin suppresses the proliferation, motility and tumourigenesis of colorectal cancer cells. Phytomedicine 56:10−20. |
2018 |
Cancer |
Colorectal |
| Thawani A, et al. (2018) XMAP215 Is a microtubule nucleation factor that functions synergistically with the y-tubulin ring complex. Nat Cell Biol 20(5):575−585 |
2018 |
Structural biology/Protein interactions |
|
| Zhang G, et al. (2018) Detection of MiR-29a in plasma patients with lumbar spinal stenosis and the clinical significance. Mol Med Rep 18(1):223−229. |
2018 |
Disease study: Biomarker research |
|
| Shen P, Chen J, Pan M. (2017) The protective effects of total paeony clycoside on ischemia/reperfusion injury in H9C2 cells via inhibition of the PI3K/Akt signaling pathway. Mol Med Rep 18:3332–3340. |
2017 |
Cell signaling |
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