An improved search experience
Discover our expanded portfolio with the latest assays for single nucleotide polymorphisms (SNPs) associated with extensively researched human diseases. Leveraging the power of AI, we have meticulously curated relevant SNPs linked to complex diseases such as diabetes, cancer, and heart disease. With our upgraded TaqMan SNP Genotyping Assay search experience, ordering assays for these SNPs has never been more seamless. Explore our advanced solutions and stay at the forefront of genetic research.
How to find your TaqMan SNP Genotyping Assay by disease
- Select your disease of interest below. We have developed 11 curated collections of TaqMan SNP Genotyping assays based on the most researched diseases. For each disease, we have developed an association ranking for SNPs associated with the disease in published literature.
- Browse the list of TaqMan SNP Genotyping assays and associated Assay IDs using the tabs below.
- Navigate to our refreshed assay search experience below the tabs to learn more about and order the assays (or search for and order multiple assay IDs.)
TaqMan SNP Genotyping assays by disease
Diabetes is a chronic disease that results in the inability to regulate blood glucose levels. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs738409 | 134 | PNPLA3 | AGGCCTTGGTATGTTCCTG CTTCAT[C/G]CCCTTCTACA GTGGCCTTATCCCTC |
C______7241_10 |
| rs10830963 | 104 | MTNR1B | GTGATGCTAAGAATTCAC ACCATCT[C/G]CTATCCAG AACCAGTAACTGCCTGG |
C___3256858_10 |
| rs1260326 | 79 | GCKR | CACAGCACCGTGGGTCAG ACCTTGC[C/T]GGTGAGA GTCCAGCCGTGACAAAGG |
C___2862880_1_ |
| rs7903146 | 72 | TCF7L2 | TAGAGAGCTAAGCACTTT TTAGATA[C/T]TATATAAT TTAATTGCCGTATGAGG |
C__29347861_10 |
| rs58542926 | 60 | TM6SF2 | GTGAGGAAGAAGGCAGG CCTGATCT[C/T]GGAGCTG TATTTGCCTTCCATGGTG |
C__89463510_10 |
Access the full list of predesigned assays for SNPs associated with diabetes here.
*Please refer to FAQs for more information on association score.
Breast cancer is one of the most commonly diagnosed form of cancer in women. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs11614913 | 45 | MIR196A2 | TTTTGAACTCGGCAACAAG AAACTG[C/T]CTGAGTTAC ATCAGTCGGTTTTCGT |
C__31185852_10 |
| rs1042522 | 38 | TP53 | AGGAGCTGCTGGTGCAGG GGCCACG[C/GGGGGAGC AGCCTCTGGCATTCTGGG |
C___2403545_10 |
| rs6983267 | 24 | CASC8 | GTCCTTTGAGCTCAGCAG ATGAAAG[G/TCACTGAG AAAAGTACAAAGAATTTT |
C__29086771_20 |
| rs2231142 | 20 | ABCG2 | GCAAGCCGAAGAGCTGC TGAGAACT[G/TTAAGTTT TCTCTCACCGTCAGAGTG |
C__15854163_70 |
| rs2910164 | 19 | MIR146A | CATGGGTTGTGTCAGTGT CAGACCT[C/GTGAAATTC AGTTCTTCAGCTGGGAT |
C__15946974_10 |
Access the full list of predesigned assays for SNPs associated with breast cancer here.
*Please refer to FAQs for more information on association score.
Obesity is a complex disease that is influenced by genetic background as well as behaviorial/lifestyle choices. Obesity can increase the risk of other diseases such as diabetes and heart disease. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs738409 | 179 | PNPLA3 | AGGCCTTGGTATGTTCCTG CTTCAT[C/G]CCCTTCTACA GTGGCCTTATCCCTC |
C______7241_10 |
| rs9939609 | 158 | FTO | GGTTCCTTGCGACTGCTGT GAATTT[A/T]GTGATGCAC TTGGATAGTCTCTGTT |
C__30090620_10 |
| rs1421085 | 100 | FTO | GGTTCCTTGCGACTGCTGT GAATTT[A/T]GTGATGCAC TTGGATAGTCTCTGTT |
C___8917103_10 |
| rs58542926 | 92 | TM6SF2 | GTGAGGAAGAAGGCAGGC CTGATCT[C/T]GGAGCTGT ATTTGCCTTCCATGGTG |
C__89463510_10 |
| rs1260326 | 73 | GCKR | CACAGCACCGTGGGTCAG ACCTTGC[C/T]GGTGAGA GTCCAGCCGTGACAAAGG |
C___2862880_1_ |
Access the full list of predesigned assays for SNPs associated with obesity here.
*Please refer to FAQs for more information on association score.
Coronary heart disease is caused by buildup of cholesterol plaques in arteries, which can reduce the amount of blood being brought to the heart. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs10757278 | 41 | N/A | AAGTCAGGGTGTGGTCATT CCGGTA[A/G]GCAGCGATG CAGAATCAAGACAGAG |
C__11841860_10 |
| rs9349379 | 41 | PHACTR1 | TCTATGCCCTTGAGATCATA TAAAA[A/G]TAGCTTAAAA TCATTGGCCATAGTT |
C___1756707_10 |
| rs10455872 | 40 | LPA | TCAGACACCTTGTTCTCAGA ACCCA[A/G]TGTGTTTATAC AGGTTAGAGGAGAA |
C__30016089_10 |
| rs738409 | 33 | PNPLA3 | AGGCCTTGGTATGTTCCTGC TTCAT[C/G]CCCTTCTACAGT GGCCTTATCCCTC |
C______7241_10 |
| rs3798220 | 32 | LPA | GCTCCAAGAACAGCCTAGAC ACTTC[C/T]ATTTCCTGAACA TGAGATTCGAGGT |
C__25930271_10 |
Access the full list of predesigned assays for SNPs associated with coronary heart disease here.
*Please refer to FAQs for more information on association score.
Colorectal cancer occurs in the large intestine of the digestive system. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs6983267 | 56 | CASC8 | GTCCTTTGAGCTCAGCAGA TGAAAG[G/T]CACTGAGAA AAGTACAAAGAATTTT |
C__29086771_20 |
| rs1042522 | 23 | TP53 | AGGAGCTGCTGGTGCAGG GGCCACG[C/G]GGGGAGC AGCCTCTGGCATTCTGGG |
C___2403545_10 |
| rs11614913 | 22 | MIR196A2 | TTTTGAACTCGGCAACAAG AAACTG[C/T]CTGAGTTAC ATCAGTCGGTTTTCGT |
C__31185852_10 |
| rs11615 | 15 | ERCC1 | TTACGTCGCCAAATTCCCA GGGCAC[A/G]TTGCGCAC GAACTTCAGTACGGGAT |
C___2532959_20 |
| rs2910164 | 12 | MIR146A | CATGGGTTGTGTCAGTGTC AGACCT[C/G]TGAAATTCA GTTCTTCAGCTGGGAT |
C__15946974_10 |
Access the full list of predesigned assays for SNPs associated with colorectal cancer here.
*Please refer to FAQs for more information on association score.
Lung cancer is a common form of cancer often caused by smoking cigarettes. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs11614913 | 39 | MIR196A2 | TTTTGAACTCGGCAACAAG AAACTG[C/T]CTGAGTTAC ATCAGTCGGTTTTCGT |
C__31185852_10 |
| rs16969968 | 30 | CHRNA5 | TAGAAACACATTGGAAGC TGCGCTC[A/G]ATTCTATT CGCTACATTACAAGACA |
C__26000428_20 |
| rs2736100 | 25 | TERT | GAAAAGCAGGGCGGGGG CAAAGCTA[A/C]AGAAAC ACTCAACACGGAAAACAAT |
C___1844009_10 |
| rs2910164 | 24 | MIR146A | CATGGGTTGTGTCAGTGT CAGACCT[C/G]TGAAATT CAGTTCTTCAGCTGGGAT |
C__15946974_10 |
| rs1051730 | 23 | CHRNA3 | AGCAGTTGTACTTGATGT CGTGTTT[A/G]TAGCCTG GGGCTTTGATGATGGCCC |
C___9510307_20 |
Access the full list of predesigned assays for SNPs associated with lung cancer here.
*Please refer to FAQs for more information on association score.
Multiple schlerosis is a chronic autoimmune disease that afflicts the central nervous system. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs6971 | 14 | TSPO | CCCCTACCTGGCCTGGCT GGCCTTC[A/G]CGACCAC ACTCAACTACTGCGTATG |
C___2512465_20 |
| rs2910164 | 13 | MIR146A | CATGGGTTGTGTCAGTGT CAGACCT[C/G]TGAAATTC AGTTCTTCAGCTGGGAT |
C__15946974_10 |
| rs10741657 | 12 | CYP2R1 | TGGTTGGGGAGATACTTT AGCAGGC[A/G]AGGGCTG TCAAGGAAAGTCTTATTA |
C___2958430_10 |
| rs10735810 | 10 | VDR | GGAAGTGCTGGCCGCCATTGCCTCC[A/G]TCCCTGTAAGAACAGCAAGCAGGCC | C__12060045_20 |
| rs6897932 | 10 | IL7R | GGGGAGATGGATCCTAT CTTACTAA[C/T]CATCAG CATTTTGAGTTTTTTCTCT |
C___2025977_10 |
Access the full list of predesigned assays for SNPs associated with multiple sclerosis here.
*Please refer to FAQs for more information on association score.
Prostate cancer is one of the most common cancers and occurs in the prostate gland in men. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs6983267 | 17 | CASC8 | GTCCTTTGAGCTCAGCAGA TGAAAG[G/T]CACTGAGAA AAGTACAAAGAATTTT |
C__29086771_20 |
| rs138213197 | 11 | HOXB13 | CACTCGGCAGGAGTAGTAC CCGCCT[C/T]CAAAGTAACC ATAAGGCACGGGAGC |
C_164436492_20 |
| rs12329760 | 11 | TMPRSS2 | CAGGACTTCCTCTGAGATG AGTACA[C/T]CTGAAGGAT GAAGTTTGGTCCGTAG |
C__25622353_20 |
| rs11614913 | 10 | MIR196A2 | TTTTGAACTCGGCAACAAG AAACTG[C/T]CTGAGTTAC ATCAGTCGGTTTTCGT |
C__31185852_10 |
| rs145204276 | 9 | ZBTB37 | GAGCAGAGAGGGGAGGG GGCGCG[AGGCA/-]AGGA AAGCTCTGGGGATGGGGGA |
C_166593916_10 |
Access the full list of predesigned assays for SNPs associated with prostate cancer here.
*Please refer to FAQs for more information on association score.
Parkinson’s disease is a progressive, neurodegenerative disorder that afflicts the central nervous system. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs1800497 | 19 | ANKK1 | CACAGCCATCCTCAAAGTGC TGGTC[A/G]AGGCAGGCGC CCAGCTGGACGTCCA |
C___7486676_10 |
| rs4680 | 16 | COMT | CCAGCGGATGGTGGATTTC GCTGGC[A/G]TGAAGGACA AGGTGTGCATGCCTGA |
C__25746809_50 |
| rs11931074 | 16 | Intergenetic | CCAATTGTGAATATGTCTTTGACTG[G/TAGGGAATTATGATTTGGAAGGCTGC | C___3208972_10 |
| rs6265 | 15 | BDNF-AS | TCCTCATCCAACAGCTCTTC TATCA[C/T]GTGTTCGAAA GTGTCAGCCAATGAT |
C__11592758_10 |
| rs429358 | 14 | APOE | GCTGGGCGCGGACATGGA GGACGTG[C/T]GCGGCCG CCTGGTGCAGTACCGCGG |
C___3084793_20 |
Access the full list of predesigned assays for SNPs associated with parkinson’s disease here.
*Please refer to FAQs for more information on association score.
Alzheimer’s disease is a complex neurodegenerative disease that is a leading cause of dementia in older individuals. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs429358 | 119 | APOE | GCTGGGCGCGGACATGGA GGACGTG[C/T]GCGGCCG CCTGGTGCAGTACCGCGG |
C___3084793_20 |
| rs11136000 | 37 | CLU | ACCAAAGCCACACCAGCT ATCAAAA[C/T]TCTCTAAC GGGCCCTTGCCACTTGA |
C__11227737_10 |
| rs6265 | 34 | BDNF | TCCTCATCCAACAGCTCTT CTATCA[C/T]GTGTTCGAA AGTGTCAGCCAATGAT |
C__11592758_10 |
| rs75932628 | 22 | TREM2 | TCCCAGCTGGCGGCACCA GGCCTTG[C/T]GCCTCCC CCAGTGCTTCATGGAGTC |
C_100657057_10 |
| rs6971 | 20 | TSPO | CCCCTACCTGGCCTGGCT GGCCTTC[A/G]CGACCAC ACTCAACTACTGCGTATG |
C___2512465_20 |
Access the full list of predesigned assays for SNPs associated with alzheimer’s disease here.
*Please refer to FAQs for more information on association score.
COVID is a respiratory disease caused by the SARS-COV-2 virus. The severity of disease is influenced by underlying health conditions such as diabetes and obesity. The top five SNPs associated with this disease are shown in the table below.
| SNP ID/RS number | Association score | Gene name | Context sequence | Assay ID |
| rs12252 | 61 | IFITM3 | GCATCTCATAGTTGGGGGG CTGGCC[A/G]CTGTTGACA GGAGAGAAGAAGGTTT |
C_175677529_10 |
| rs12329760 | 47 | TMPRSS2 | CAGGACTTCCTCTGAGATG AGTACA[C/T]CTGAAGGAT GAAGTTTGGTCCGTAG |
C__25622353_20 |
| rs3367 | 40 | PCBP3 | AATAATACGGTGTTTTGAA TGTCAT[A/G]CATGGCTTTT CCTGTTGAAACATCT |
C___9481649_1_ |
| rs10735079 | 29 | OAS3 | TGGCTAGCAGTAGGGGCCT GGGGAC[A/G]AAACCAGAA TTCTGCAAAATCTTGT |
C__31831768_10 |
| rs4231 | 27 | PHF1 CUTA | AGCTGGGATGTACCTGGAGAGATAG[C/G]GGGTAGTTCTCCCTACTGCCCAGGC | C___7515638_10 |
Access the full list of predesigned assays for SNPs associated with COVID here.
*Please refer to FAQs for more information on association score.
Assay search and ordering tool
Why are SNPs important for human health research?
SNPs are a type of genetic variation that occurs commonly within the human genome. Since SNPs can be located on the same genetic loci with disease-causing alleles, they often serve as biological markers for these susceptibility traits. Thus, an individual’s SNP genotype can be used to predict their risk for developing physical and mental disease based on these associations.
A crucial focus of research into complex diseases such as diabetes, cancer, and heart disease, is to catalog and understand the myriad of SNP variants that are associated with or may contribute to disease phenotypes.
Frequently asked questions (FAQs)
Q: What is the score assigned to each SNP?
Leveraging an AI engine, a score was determined to map the SNP associations with each disease within published literature. This approach integrates co-occurrence data within articles along with NLP to calculate association scores.
Q: Are each of the TaqMan SNP Genotyping Assay IDs functionally tested?
A: Yes, each assay design is functionally tested with 20 normal human genomic DNAs.
Q: What does an association between a SNP and a disease indicate?
A: This association indicates that this SNP has been identified in published research regarding the disease. This association is intended for research purposes and does not indicate diagnostic value of the SNP for the disease of interest.
Q: What literature was used to curate and compile the list of SNPs by disease?
A: The entire published literature was utilized using a data science approach to generate the lists. Thus, each list contains many citations across the literature. For specific questions about citations, please contact TechSupport@thermofisher.com.
For Research Use Only. Not for use in diagnostic procedures.