How does LABScreen work?
LABScreen products use a panel of color-coded microbeads, coated with HLA antigens. Beads coated with these different antigens can be combined in one suspension in a single test. The serum is incubated with LABScreen beads and any HLA antibodies in the serum bind to the antigens and are labeled with R-Phycoerythrin (PE) conjugated goat antihuman IgG. The LABScan 100 or LABScan3D detects fluorescent emission of the PE from each bead, allowing nearly real-time data acquisition.
Bead-based multiplexing for antibody testing
- Determines the presence or measurement of specific HLA Class I and Class II, MICA, and HNA antibodies in human sera or plasma samples
- Similar workflow for all LABScreen products
- Multiplex analysis enhances lab automation and lowers labor costs, reagents and assay time 96 samples can be tested sequentially using the X-Y platform
- Different LABScreen assays can be batched together on the same run
- Test can be completed in approximately 2.5 hours
Workflow
Not all products are CE marked or have 510(k) clearance for sale in the U.S. Availability of products in each country depends on local regulatory marketing authorization status.