Table 10.2 Rhodamine 110–based bis-peptide substrates.
| Cat. No. | Proteinase Substrate * | Enzymes † |
|---|---|---|
| R22122 | (Asp)2-R110 | caspase-3 and other apoptosis-related proteases  |
| R6506 | (CBZ-Ala-Ala-Ala-Ala)2-R110 | elastase |
| R33752 | (CBZ-Ala-Ala-Asp)2-R110 | granzyme B |
| R6508 | (CBZ-Ala-Arg)2-R110 | trypsin |
| R6501 | (CBZ-Arg)2-R110 | trypsin |
| R22120 | (CBZ-Asp-Glu-Val-Asp)2-R110 | caspase-3, -6, -7, -8, -10 |
| R6505 | (CBZ-Ile-Pro-Arg)2-R110 | trypsin |
| R22125 R22126 | (CBZ-Ile-Glu-Thr-Asp)2-R110 | caspase-8 |
| R33753 | (CBZ-Leu-Glu-Glu-Asp)2-R110 | caspase-13 |
| R6502 | (CBZ-Phe-Arg)2-R110 | plasmin, cathepsin L |
| R33750 | (CBZ-Tyr-Val-Ala-Asp)2-R110 | caspase-1, -4 |
| R33755 | (CBZ-Val-Asp-Val-Ala-Asp)2-R110 | caspase-2 |
| R33754 | (CBZ-Val-Glu-Ile-Asp)2-R110 | caspase-6 |
| R22124 | (p-tosyl-Gly-Pro-Arg)2-R110 | thrombin |
| * CBZ = benzyloxycarbonyl; R110 = rhodamine 110; SC = succinoyl; p-tosyl = p-toluenesulfonyl. † Caspase substrates can often be cleaved by multiple enzymes. The caspase most often associated with the given peptide sequence is listed first. | ||
仅供科研使用，不可用于诊断目的。