Product References
Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection.
Science advances
Eislmayr K,Bestehorn A,Morelli L,Borroni M,Vande Walle L,Lamkanfi M,Kovarik P
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Fri Mar 04 00:00:00 EST 2022
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Cancer cell
Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Mon May 11 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Increased baseline RASGRP1 signals enhance stem cell fitness during native hematopoiesis.
Oncogene
Karra L,Romero-Moya D,Ksionda O,Krush M,Gu Z,Mues M,Depeille P,Mullighan C,Roose JP
48-0161 was used in Flow cytometry/Cell sorting to expand RASGRP1 expression surveys in pediatric T-ALL and generated a RoLoRiG mouse model crossed to Mx1CRE to determine the consequences of induced RASGRP1 overexpression in primary hematopoietic cells.
Sun Nov 01 00:00:00 EDT 2020
Inflammatory osteolysis is regulated by site-specific ISGylation of the scaffold protein NEMO.
eLife
Adapala NS,Swarnkar G,Arra M,Shen J,Mbalaviele G,Ke K,Abu-Amer Y
48-0161 was used in Flow cytometry/Cell sorting to suggest that NEMO serves as a toolkit to fine-tune specific signals in physiologic and pathologic conditions.
Mon Mar 23 00:00:00 EDT 2020
Metabolic Imaging Reveals a Unique Preference of Symmetric Cell Division and Homing of Leukemia-Initiating Cells in an Endosteal Niche.
Cell metabolism
Hao X,Gu H,Chen C,Huang D,Zhao Y,Xie L,Zou Y,Shu HS,Zhang Y,He X,Lai X,Zhang X,Zhou BO,Zhang CC,Chen GQ,Yu Z,Yang Y,Zheng J
48-0161 was used in Flow cytometry/Cell sorting to provide a unique angle for the study of metabolisms in stem cells, and may lead to development of novel strategies for cancer treatment.
Tue Apr 02 00:00:00 EDT 2019
Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation.
Cell stem cell
Viny AD,Bowman RL,Liu Y,Lavallée VP,Eisman SE,Xiao W,Durham BH,Navitski A,Park J,Braunstein S,Alija B,Karzai A,Csete IS,Witkin M,Azizi E,Baslan T,Ott CJ,Pe'er D,Dekker J,Koche R,Levine RL
48-0161 was used in Flow cytometry/Cell sorting to illustrate a role for Stag2 in transformation and transcriptional dysregulation distinct from its shared role with Stag1 in chromosomal segregation.
Thu Nov 07 00:00:00 EST 2019
Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity.
Cell
Mitroulis I,Ruppova K,Wang B,Chen LS,Grzybek M,Grinenko T,Eugster A,Troullinaki M,Palladini A,Kourtzelis I,Chatzigeorgiou A,Schlitzer A,Beyer M,Joosten LAB,Isermann B,Lesche M,Petzold A,Simons K,Henry I,Dahl A,Schultze JL,Wielockx B,Zamboni N,Mirtschink P,Coskun Ü,Hajishengallis G,Netea MG,Chavakis T
48-0161 was used in Flow cytometry/Cell sorting to discover that modulation of myeloid progenitors in the bone marrow is an integral component of trained immunity.
Thu Jan 11 00:00:00 EST 2018
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.
Nature communications
Lam J,van den Bosch M,Wegrzyn J,Parker J,Ibrahim R,Slowski K,Chang L,Martinez-Høyer S,Condorelli G,Boldin M,Deng Y,Umlandt P,Fuller M,Karsan A
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Wed Jun 20 00:00:00 EDT 2018
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Nature
Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Thu Apr 06 00:00:00 EDT 2017
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Cell
Cimmino L,Dolgalev I,Wang Y,Yoshimi A,Martin GH,Wang J,Ng V,Xia B,Witkowski MT,Mitchell-Flack M,Grillo I,Bakogianni S,Ndiaye-Lobry D,Martín MT,Guillamot M,Banh RS,Xu M,Figueroa ME,Dickins RA,Abdel-Wahab O,Park CY,Tsirigos A,Neel BG,Aifantis I
48-0161 was used in Flow cytometry/Cell sorting to determine the role of TET2 deficiency in leukaemia stem cell maintenance.
Thu Sep 07 00:00:00 EDT 2017
Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy.
Nature communications
Liu Z,Ravindranathan R,Kalinski P,Guo ZS,Bartlett DL
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Mon Mar 27 00:00:00 EDT 2017
Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature.
Nature communications
Reismann D,Stefanowski J,Günther R,Rakhymzhan A,Matthys R,Nützi R,Zehentmeier S,Schmidt-Bleek K,Petkau G,Chang HD,Naundorf S,Winter Y,Melchers F,Duda G,Hauser AE,Niesner RA
48-0161 was used in Flow cytometry/Cell sorting to develop longitudinal intravital imaging of the bone marrow to analyse cellular dynamics within the deep marrow.
Mon Dec 18 00:00:00 EST 2017
Fibrillin-1 microfibrils influence adult bone marrow hematopoiesis.
Matrix biology : journal of the International Society for Matrix Biology
Smaldone S,Bigarella CL,Del Solar M,Ghaffari S,Ramirez F
48-0161 was used in Flow cytometry/Cell sorting to investigate adult haematopoiesis in mice with Cre-mediated inactivation of the fibrillin-1 gene in the mesenchyme of the forming limbs.
Wed Dec 20 00:00:00 EST 2017
Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis.
mBio
Schlam D,Canton J,Carreño M,Kopinski H,Freeman SA,Grinstein S,Fairn GD
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Immunofluorescence
Tue Apr 05 00:00:00 EDT 2016
Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis.
mBio
Schlam D,Canton J,Carreño M,Kopinski H,Freeman SA,Grinstein S,Fairn GD
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Immunofluorescence
Tue Apr 05 00:00:00 EDT 2016
Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma.
Journal for immunotherapy of cancer
Patel MA,Kim JE,Theodros D,Tam A,Velarde E,Kochel CM,Francica B,Nirschl TR,Ghasemzadeh A,Mathios D,Harris-Bookman S,Jackson CC,Jackson C,Ye X,Tran PT,Tyler B,Coric V,Selby M,Brem H,Drake CG,Pardoll DM,Lim M
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Wed May 18 00:00:00 EDT 2016
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.
Genome medicine
Sonnet M,Claus R,Becker N,Zucknick M,Petersen J,Lipka DB,Oakes CC,Andrulis M,Lier A,Milsom MD,Witte T,Gu L,Kim-Wanner SZ,Schirmacher P,Wulfert M,Gattermann N,Lübbert M,Rosenbauer F,Rehli M,Bullinger L,Weichenhan D,Plass C
48-0161 was used in Flow cytometry/Cell sorting to investigate the onset of aberrant DNA methylation events and their dynamics during leukemic progression.
Thu Jun 19 00:00:00 EDT 2014
Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice.
Blood
Doyle AD,Jacobsen EA,Ochkur SI,McGarry MP,Shim KG,Nguyen DT,Protheroe C,Colbert D,Kloeber J,Neely J,Shim KP,Dyer KD,Rosenberg HF,Lee JJ,Lee NA
48-0161 was used in Flow cytometry/Cell sorting to investigate the contributions of the granule proteins MBP-1 and EPX to eosinophil activity using double knockout mice.
Thu Aug 01 00:00:00 EDT 2013
The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.
Cell
Rankin EB,Wu C,Khatri R,Wilson TL,Andersen R,Araldi E,Rankin AL,Yuan J,Kuo CJ,Schipani E,Giaccia AJ
48-0161 was used in Flow cytometry/Cell sorting to study the role of osteoblasts in the production of EPO and modulation of erythropoiesis through the HIF signalling pathway.
Fri Mar 30 00:00:00 EDT 2012
Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms.
The American journal of pathology
Ninković J,Roy S
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms.
The American journal of pathology
Ninković J,Roy S
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.
PloS one
Pello OM,Chèvre R,Laoui D,De Juan A,Lolo F,Andrés-Manzano MJ,Serrano M,Van Ginderachter JA,Andrés V
Published figure using CD16/CD32 monoclonal antibody (Product # 48-0161-82) in Flow Cytometry
Mon Feb 25 00:00:00 EST 2013
CD11c+ dendritic cells and B cells contribute to the tumoricidal activity of anti-DR5 antibody therapy in established tumors.
Journal of immunology (Baltimore, Md. : 1950)
Haynes NM,Hawkins ED,Li M,McLaughlin NM,Hämmerling GJ,Schwendener R,Winoto A,Wensky A,Yagita H,Takeda K,Kershaw MH,Darcy PK,Smyth MJ
48-0161 was used in Flow cytometry/Cell sorting to investigate the cellular and molecular mechanisms contributing to the antitumour activity of selective antagonism of death receptors 4 and 5, showing that CD11c+ dendritic cells and B cells contribute to the tumoricidal activity of anti-DR5 antibody therapy.
Thu Jul 01 00:00:00 EDT 2010