Product References
R274X-mutated Phf6 increased the self-renewal and skewed T cell differentiation of hematopoietic stem cells.
iScience
Lan Y,Yuan S,Guo T,Hou S,Zhao F,Yang W,Cao Y,Chu Y,Jiang E,Yuan W,Wang X
17-0161-82 was used in Flow cytometry/Cell sorting to demonstrate that Phf6R274X plays a critical role in fine-tuning T cells and HSC homeostasis.
Fri Jun 16 00:00:00 EDT 2023
Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection.
Science advances
Eislmayr K,Bestehorn A,Morelli L,Borroni M,Vande Walle L,Lamkanfi M,Kovarik P
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Fri Mar 04 00:00:00 EST 2022
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Cholesterol and sphingomyelin are critical for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages.
The Journal of biological chemistry
Bryan AM,You JK,Li G,Kim J,Singh A,Morstein J,Trauner D,Pereira de Sá N,Normile TG,Farnoud AM,London E,Del Poeta M
17-0161-82 was used in Flow Cytometry to suggest that lipid rafts are critical for facilitating FcγRIII-mediated phagocytosis of C. neoformans.
Wed Dec 01 00:00:00 EST 2021
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Cancer cell
Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Mon May 11 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
TNFAIP3 Plays a Role in Aging of the Hematopoietic System.
Frontiers in immunology
Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT
17-0161-82 was used in Flow Cytometry to find that the expression of A20 is significantly reduced in aged hematopoietic stem and progenitor cells (HSPC) as compared to young HSPC.
Wed Apr 28 00:00:00 EDT 2021
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.
Nature communications
Lam J,van den Bosch M,Wegrzyn J,Parker J,Ibrahim R,Slowski K,Chang L,Martinez-Høyer S,Condorelli G,Boldin M,Deng Y,Umlandt P,Fuller M,Karsan A
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Wed Jun 20 00:00:00 EDT 2018
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Nature
Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Thu Apr 06 00:00:00 EDT 2017
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Nature immunology
Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT
17-0161 was used in Flow cytometry/Cell sorting to examine the significance of ubiquitin signalling in coordinating RNA processing by Toll-like receptor pathways during an immune response and in premalignant haematologic diseases.
Wed Feb 01 00:00:00 EST 2017
Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy.
Nature communications
Liu Z,Ravindranathan R,Kalinski P,Guo ZS,Bartlett DL
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Mon Mar 27 00:00:00 EDT 2017
MiR-125a Is a critical modulator for neutrophil development.
PLoS genetics
Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N
17-0161 was used in Flow cytometry/Cell sorting to reveal a microRNA regulating granulocyte development and supporte a model in which miR-125a acts as a fine-tuner of granulopoiesis.
Sun Oct 01 00:00:00 EDT 2017
Genomic and immunologic factors associated with viral pathogenesis in a lethal EV71 infected neonatal mouse model.
Molecular medicine reports
Yue Y,Li P,Song N,Li B,Li Z,Guo Y,Zhang W,Wei MQ,Gai Z,Meng H,Wang J,Qin L
17-0161 was used in Flow cytometry/Cell sorting to understand the virological features of enterovirus 71 and the host responses resulting from enterovirus 71 infection.
Sun May 01 00:00:00 EDT 2016
Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis.
mBio
Schlam D,Canton J,Carreño M,Kopinski H,Freeman SA,Grinstein S,Fairn GD
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Tue Apr 05 00:00:00 EDT 2016
Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma.
Journal for immunotherapy of cancer
Patel MA,Kim JE,Theodros D,Tam A,Velarde E,Kochel CM,Francica B,Nirschl TR,Ghasemzadeh A,Mathios D,Harris-Bookman S,Jackson CC,Jackson C,Ye X,Tran PT,Tyler B,Coric V,Selby M,Brem H,Drake CG,Pardoll DM,Lim M
17-0161 was used in Flow cytometry/Cell sorting to provide preclinical evidence for the use of anti-GITR (1) non-depleting antibodies in combination with SRS in GBM.
Wed May 18 00:00:00 EDT 2016
Functions of miR-146a and miR-222 in Tumor-associated Macrophages in Breast Cancer.
Scientific reports
Li Y,Zhao L,Shi B,Ma S,Xu Z,Ge Y,Liu Y,Zheng D,Shi J
17-0161 was used in Flow cytometry/Cell sorting to study the role of endogenous miRNAs in controlling the polarisation and function of tumour-associated macrophages in breast cancer.
Tue Dec 22 00:00:00 EST 2015
Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner.
Blood
Capitano ML,Nemeth MJ,Mace TA,Salisbury-Ruf C,Segal BH,McCarthy PL,Repasky EA
17-0161 was used in Flow cytometry/Cell sorting to study the factors limiting the immune system recovery process after chemo- and radiotherapy.
Thu Sep 27 00:00:00 EDT 2012
Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms.
The American journal of pathology
Ninković J,Roy S
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms.
The American journal of pathology
Ninković J,Roy S
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.
PloS one
Pello OM,Chèvre R,Laoui D,De Juan A,Lolo F,Andrés-Manzano MJ,Serrano M,Van Ginderachter JA,Andrés V
Published figure using CD16/CD32 monoclonal antibody (Product # 17-0161-82) in Flow Cytometry
Mon Feb 25 00:00:00 EST 2013
A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.
Lipids
Varney ME,Buchanan JT,Dementieva Y,Hardman WE,Sollars VE
17-0161 was used in Flow cytometry/Cell sorting to examine the effects of n-3 and n-6 fatty acids on haematopietic stem and progenitor cells in vivo in the mouse.
Sat Jan 01 00:00:00 EST 2011
Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development.
Blood
Böiers C,Buza-Vidas N,Jensen CT,Pronk CJ,Kharazi S,Wittmann L,Sitnicka E,Hultquist A,Jacobsen SE
17-0161 was used in Flow cytometry/Cell sorting to investigate the role of FLT3 in early granulocyte-monocyte progenitors (GMPs), showing that most GMPs are derived from FLT3-expressing progenitors.
Thu Jun 17 00:00:00 EDT 2010
Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality.
Journal of leukocyte biology
Marchlik E,Thakker P,Carlson T,Jiang Z,Ryan M,Marusic S,Goutagny N,Kuang W,Askew GR,Roberts V,Benoit S,Zhou T,Ling V,Pfeifer R,Stedman N,Fitzgerald KA,Lin LL,Hall JP
17-0161 was used in Flow cytometry/Cell sorting to analyse the immune problems arising from production of a truncated Tbk1 protein in mice.
Wed Dec 01 00:00:00 EST 2010
Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.
Diabetes
Parker MJ,Xue S,Alexander JJ,Wasserfall CH,Campbell-Thompson ML,Battaglia M,Gregori S,Mathews CE,Song S,Troutt M,Eisenbeis S,Williams J,Schatz DA,Haller MJ,Atkinson MA
17-0161 was used in Flow cytometry/Cell sorting to investigate the use of ATG and GCSF in therapies to reverse overt hyperglycaemia in a diabetic mouse model.
Thu Oct 01 00:00:00 EDT 2009