">

Videos

The Invitrogen iBright Imaging Systems capture images and analyze data from your western blots and gels efficiently and easily. With a blend of modern design and performance, iBright Imaging Systems enhance your imaging workflow.

Instrument overview and how-to videos

Note that we make regular updates to instrument experience and function through firmware updates. The videos above accurately reflect the majority of instrument functions as featured, but some workflow and feature enhancements may not be reflected in these videos.

iBright Analysis Software how-to videos

Note that we've updated our iBright Analysis Software interface to further streamline the look and enhance the user experience. While there may be some differences in the visual elements of the iBright Analysis Software interface in these videos below, many of the functions and actions described are applicable to the current version of iBright Analysis Software.

1:00 – Brief overview of iBright Imaging Systems and iBright Analysis Software

4:40 – Gallery tab overview (importing images, gallery organization, adding and removing images from tray)

7:23 – Adjust tab overview (editing functions: crop, straighten, rotate, flip, invert, false color, contrast, show saturation)

19:15 – Analyze tab overview (automatic analysis, analysis frames, adding and removing bands from analysis, resizing band frames, molecular weight analysis, data table, auto-enhance, lane profile)

36:32 – Annotate tab overview (labeling images)

44:25 -  Generating and exporting an analysis report

47:42 – Image export 

51:30 – Renaming image files

52:15 – Question & answer session

1:10 – Overview of iBright Imaging Systems and considerations for achieving quantitative western blots

19:45 – Brief overview of Gallery tab functionality and image selection for analysis

21:45 – Brief overview of Adjust tab functionality

23:00 – Analyze tab (auto-analysis, lane and band adjustments)

26:30 – Normalization analysis with housekeeping proteins (HKPs)

31:30 – Background correction (local background correction, lane profile, and rolling ball background correction)

37:50 – Relative quantitation

39:30 – Total lane protein (TPN) normalization with No-Stain Protein Labeling Reagent

43:40 – Total lane protein (TPN) normalization “across the file” with membrane stain 

50:10 – Generating an image report

53:00 – Question & answer session


Scientist: Guillaume Pidoux
Location: France
Abstract: My group focuses on the spatiotemporal regulation of cAMP signaling in cardiac physiological and pathophysiological conditions.

 

The heart ensures that peripheral organs are perfused with blood and nutrients. Any alterations of this function lead to heart injury and failure. A-kinase anchoring proteins (AKAPs) are a family of scaffolding proteins that anchors protein kinase-A (PKA), and thus plays a central role in the regulation of cardiac function under physiological and pathological conditions.

 

We focus on understanding the direct role of AKAPs in cardiac physiology and during the occurrence of cardiomyopathies. We utilize molecular biology tools to direct shRNA mediated knockdown and reconstitution assays combined with biochemical assays (i.e., immunoblot, co-immunoprecipitation, TR-FRET and Alpha-Screen). We further support our studies with state-of-the-art confocal imaging (i.e., live-cell FRAP & FLIP, proximity ligation assay and super-resolution imaging).

 

Furthermore, we aim to develop protein-protein interactor (PPI) disrupting peptides to counteract anchored-PKA dependent cellular processes that are modified during cardiac pathologies. These specific PPIs could serve as new potential specific cardiac therapeutic agents.

 

Favorite feature of the iBright system: Easy-to-use interface allowing the acquisition of excellent resolution pictures.

 


Documentation and literature


Education and tools

Protein Electrophoresis and Western Blotting Education Center

Find the resources to succeed as you plan and perform your western blot experiments. Find detailed protocols, quick tips and tricks, how-to-videos, webinars and more.

 

Protein Electrophoresis and Western blotting Troubleshooting Guide  

Gaining publication quality results straightaway is not exactly the norm when performing western blotting- this guide provides step-by-step tips and tricks to obtain high-quality, publishable western results.

BlotBuilder Product Selection Tool

Get western blot solutions designed specifically for your target proteins and experimental needs. Use this tool to get a personalize western blot protocol.


 


Firmware and Software Updates

We regularly make firmware and software improvements for iBright Imaging Systems and iBright Analysis Software. To access the firmware and software updates and to review release notes, please visit our update page.

 

 


Citations

Find relevant citations from peer-reviewed journals where specific research results were generated using the iBright Imaging platforms.

No records were found matching your criteria

   
Title Year Category Subcategory
Bavlovic J, et al. (2023) Intact O-antigen is critical structure for the exceptional tubular shape of outer membrane vesicles in Francisella tularensis. Microbiol Res 269:127300. 2023Microorganisms and model organisms
Delaunay JL, et al. (2023) Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases. Int J Mol Sci 24(2):1236. 2023Other
Losada JZ, et al. (2023) Apoptosis-modulatory miR-361-3p as a novel treatment target in endocrine-resistant breast cancer. J Endocrinol Jan 1 doi: 10.1530/JOE-22-0229. 2023Cancer studiesBreast cancer
Thangavel H, et al. (2023) Susceptibility of Fat Tissue to SARS-CoV-2 Infection in Female hACE2 Mouse Model. Int J Mol Sci 24(2):1314. 2023Cell signaling
Gamage CDB, et al. (2023) Libertellenone T, a Novel Compound Isolated from Endolichenic Fungus, Induces G2/M Phase Arrest, Apoptosis, and Autophagy by Activating the ROS/JNK Pathway in Colorectal Cancer Cells. Cancers (Basel) 15(2):489.2023Cancer studiesColorectal cancer
Zhang X, et al. (2023) Oridonin Induces Apoptosis in Esophageal Squamous Cell Carcinoma by Inhibiting Cytoskeletal Protein LASP1 and PDLIM1. Molecules 28(2):805. 2023Cancer studiesSquamous cell carcinoma
Petazzi P, et al. (2023) Global Impairment of Immediate-Early Genes Expression in Rett Syndrome Models and Patients Linked to Myelination Defects. Int J Mol Sci 24(2):1453. 2023Neurobiology
Oswal N, et al. (2023) Diets Differently Regulate Pulmonary Pathogenesis and Immune Signaling in Mice during Acute and Chronic Mycobacterium tuberculosis Infection. Life (Basel) 13(1):228. 2023Microorganisms and model organisms
Hsu CL, et al. (2023) Neuroprotective Effects of Erinacine A on an Experimental Model of Traumatic Optic Neuropathy. Int J Mol Sci 24(2):1504. 2023Neurobiology
Chernikov IV, et al. (2023) siRNA-Mediated Timp1 Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury. Int J Mol Sci 24(2):1641.2023Other
Forte E, et al. (2023) Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in Ori Lyt. Microbiol Spectr Jan 16 doi: 10.1128/spectrum.03144-22. 2023Other
Südfeld C, et al. (2023) Expression of glycerol-3-phosphate acyltransferase increases non-polar lipid accumulation in Nannochloropsis oceanica. Microb Cell Fact 22(1):12. 2023Other
Sloas DC, et al. (2023) Tension-tuned receptors for synthetic mechanotransduction and intercellular force detection. Nat Biotechnol Jan 16 doi: 10.1038/s41587-022-01638-y. 2023Method development
Kong Y, et al. (2023) HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy. EMBO Mol Med Jan 16 doi: 10.15252/emmm.202216525. 2023Other
Che Y, et al. (2023) Bile acids target mitofusin 2 to differentially regulate innate immunity in physiological versus cholestatic conditions. Cell Rep 42(1):112011. 2023Mitochondrial studies
Yoshida M, et al. (2023) An antisense amido-bridged nucleic acid gapmer oligonucleotide targeting SRRM4 alters REST splicing and exhibits anti-tumor effects in small cell lung cancer and prostate cancer cells. Cancer Cell Int 23(1):8. 2023Cancer studiesLung cancer
Woodburn SC, et al. (2023) Depletion of microglial BDNF increases susceptibility to the behavioral and synaptic effects of chronic unpredictable stress. Brain Behav Immun Jan 18 doi: 10.1016/j.bbi.2023.01.014. 2023Neurobiology
Shang J, et al. (2023) Inhibition of Klf10 Attenuates Oxidative Stress-Induced Senescence of Chondrocytes via Modulating Mitophagy. Molecules 28(3)924. 2023Drug mechanism
Silva RM, et al. (2023) Anion exchange chromatography-based platform for the scalable purification of extracellular vesicles derived from human mesenchymal stromal cells. Sep Purif Technol 310:123238. 2023Method development
Foliaki ST, et al. (2023) Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction. PLoS Genet 19(1):e1010565.2023Neurobiology
Jung YH, et al. (2023) A conformation-selective protein binder for a KRAS mutant inhibits the interaction between RAS and RAF. Biochem Biophys Res Commun 645:110-117. 2023Structural biology/protein interactions
Wang W, et al. (2023) The impact of osmotic stresses on the biofilm formation, immunodetection, and morphology of Aeromonas hydrophila. Microbiol Res 269:127301. 2023Microorganisms and model organisms
Morales A, et al. (2023) PACAP and acetylcholine cause distinct Ca2+ signals and secretory responses in chromaffin cells. J Gen Physiol 155(2):e202213180. 2023Cell signaling
Ebelt ND and Manuel ER (2023) 5-Azacytidine-Mediated Modulation of the Immune Microenvironment in Murine Acute Myeloid Leukemia. Cancers 15(1):118. 2023Cancer studiesGeneral
AlZahrani S, et al. (2023) Anti-Inflammatory Effect of Specialized Proresolving Lipid Mediators on Mesenchymal Stem Cells: An In Vitro Study. Cells 12(1):122. 2023Stem cells
Wang L, et al. (2023) Nicotinamide Mononucleotide Ameliorates Silica-Induced Lung Injury through the Nrf2-Regulated Glutathione Metabolism Pathway in Mice. Nutrients 15(1): 143. 2023Other
Kim YK, et al. (2023) Transcriptome Profile in the Mouse Brain of Hepatic Encephalopathy and Alzheimer's Disease. Int. J. Mol. Sci 24(1): 675. 2023Neurobiology
Marianna B, et al. (2023) Design, Synthesis and Antiproliferative Evaluation of Bis-Indole Derivatives with a Phenyl Linker: Focus on Autophagy. Molecules 28(1): 251. 2023Cancer studiesLung cancer
Kim JY, et al. (2023) Antioxidant, Anti-Apoptotic, and Anti-Inflammatory Effects of Farrerol in a Mouse Model of Obstructive Uropathy. Curr. Issues Mol. Biol 45(1): 337-352. 2023Drug mechanism
Montero‐Blay A, et al. (2023) Bacterial expression of a designed single‐chain IL‐10 prevents severe lung inflammation. Mol Syst Biol Jan 4 doi: 10.15252/msb.202211037. 2023Drug mechanism
Thangavel H, et al. (2023) Diets Differently Regulate Tumorigenesis in Young E0771 Syngeneic Breast Cancer Mouse Model. J. Clin. Med 12(2): 413.2023Cancer studiesBreast cancer
Verma A, et al. (2023) P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress. Int. J. Mol. Sci 24(2):950. 2023Mitochondrial studies
Sokanovic SJ, et al. (2023) Common and female-specific roles of protein tyrosine phosphatase receptors N and N2 in mice reproduction. Sci Rep 13(1):355. 2023Other
Hung SH, et al. (2023) Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5′-monophosphate as the biological substrate. Nucleic Acids Res Jan 5 doi: 10.1093/nar/gkac1231. 2023Other
Alway SE, et al. (2023) Mitochondria transplant therapy improves regeneration and restoration of injured skeletal muscle. J Cachexia Sarcopenia Muscle Jan 5 doi: 10.1002/jcsm.13153. 2023Mitochondrial studies
Nielsen SSE, et al. (2023) Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells. Fluids Barriers CNS 20(1):2.2023Neurobiology
Woo JH, et al. (2023) Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage. Part Fibre Toxicol 20(1):2. 2023Mitochondrial studies
Itoh T, et al. (2023) Phenolic Glycosides Citrulluside H and Citrulluside T Isolated From Young Watermelon (Citrullus lanatus) Fruit Have Beneficial Effects Against Cutibacterium acnes-Induced Skin Inflammation. Natural Product Communications 18(1). 2023Plant sciences
Chen TW, et al. (2022) Vitamin B3 Provides Neuroprotection via Antioxidative Stress in a Rat Model of Anterior Ischemic Optic Neuropathy. Antioxidants (Basel) 11(12):2422. 2022Neurobiology
Dorajoo R, et al. (2022) Vascular smooth muscle cells in low SYNTAX scores coronary artery disease exhibit proinflammatory transcripts and proteins correlated with IL1B activation. Atherosclerosis Dec 17 doi: 10.1016/j.atherosclerosis.2022.12.005. 2022Other
Ceyzériat K, et al. (2022) Low-dose brain irradiation normalizes TSPO and CLUSTERIN levels and promotes the non-amyloidogenic pathway in pre-symptomatic TgF344-AD rats. J Neuroinflammation 19(1):311.2022Neurobiology
Erzurumlu Y, et al. (2022) 1, 25 (OH) 2 D3 induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells. Cell Signal Dec 22 doi: 10.1016/j.cellsig.2022.110577. 2022Cell signaling
van Vliet VJE, et al. (2022) Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. PLoS Pathog 18(12):e1011065. 2022Microorganisms and model organisms
Sato T, et al. (2022) Fibrosis resolution in the mouse liver: role of Mmp12 and potential role of Calpain ½. Matrix Biol Plus 17: 100127. 2022Other
Chen J, et al. (2022) Building bioorthogonal click-release capable artificial receptors on cancer cell surface for imaging, drug targeting and delivery. Acta Pharm Sin B. Dec 28 doi: 10.1016/j.apsb.2022.12.018. 2022Cancer studiesGeneral
Li Z, et al. (2022) Sodium para-aminosalicylic acid ameliorates brain neuroinflammation and behavioral deficits in juvenile lead-exposed rats by modulating MAPK signaling pathway and alpha-synuclein. Toxicol Lett Dec 28 doi: 10.1016/j.toxlet.2022.12.013.2022Neurobiology
Cesaro G, et al. (2022) Trypanosoma brucei RRP44: a versatile enzyme for processing structured and non-structured RNA substrates. Nucleic Acids Res Dec 30 doi: 10.1093/nar/gkac1199. 2022Other
Shiohara A, et al. (2022) SARS‐CoV‐2 Virus Detection Via a Polymeric Nanochannel‐Based Electrochemical Biosensor. Small Dec 30 doi: 10.1002/smll.202205281. 2022Method development
Chan K, et al. (2022) Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors. Heliyon Dec 30 doi: 10.1016/j.heliyon.2022.e12744.2022CRISPR
Seo S, et al. (2022) Neuro‐Glia‐Vascular‐on‐a‐Chip System to Assess Aggravated Neurodegeneration via Brain Endothelial Cells upon Exposure to Diesel Exhaust Particles. Adv Funct Mater Dec 20 doi: 10.1002/adfm.202210123. 2022Neurobiology
Alejaldre L, et al. (2022) Tuning Selectivity in CalA Lipase: Beyond Tunnel Engineering. Biochemistry Dec 29 doi: 10.1021/acs.biochem.2c00513. 2022Other
Kang H, et al. (2022) DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma. Cell Rep Med Dec 22 doi: 10.1016/j.xcrm.2022.100880. 2022Cancer studiesBrain cancer
Zhu Y and Hart GW (2022) Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin. Cell Dec 30 doi: 10.1016/j.cell.2022.12.016. 2022Method development
Saghaug C, et al. (2022) Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia. Int J Parasitol Drugs Drug Resist 21:51-60. 2022Microorganisms and model organisms
Bayaraa O, et al. (2022) Nanoceria-GO-intercalated multicellular spheroids revascularize and salvage critical ischemic limbs through anti-apoptotic and pro-angiogenic functions. Biomaterials Nov 14 doi: 10.1016/j.biomaterials.2022.121914. 2022Cell signaling
Zekri-Nechar K, et al. (2022) Spike Protein Subunits of SARS-CoV-2 Alter Mitochondrial Metabolism in Human Pulmonary Microvascular Endothelial Cells: Involvement of Factor Xa. Dis Markers Nov 18 doi: 10.1155/2022/1118195. 2022Mitochondrial studies
Kim H, et al. (2022) Simultaneous Quantification of Apolipoprotein C-III O-Glycoforms by Protein-MRM. J Proteome Res Nov 21 doi: 10.1021/acs.jproteome.2c00490. 2022Structural biology/protein interactions
Wu MY, et al. (2022) Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles. Heliyon 8(11):e11751. 2022Disease studyBiomarker research
Jacquet S, et al. (2022) Adaptive duplication and genetic diversification of protein kinase R contribute to the specificity of bat-virus interactions. Sci Adv 8(47):eadd7540. 2022Disease studyBiomarker research
Underwood J, et al. (2022) Anaplasma phagocytophilum Transmission Activates Immune Pathways While Repressing Wound Healing in the Skin. Life 12(12): 1965. 2022Other
Piras R, et al. (2022) circCsnk1g3-and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment. Nat Commun 13(1):7243. 2022Cancer studiesGeneral
Palomar-Siles M, et al. (2022) Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine. Cell Death Dis 13(11):997.2022Cancer studiesGeneral
Park JH, et al. (2022) Protective Effects of Carnosol on Renal Interstitial Fibrosis in a Murine Model of Unilateral Ureteral Obstruction. Antioxidants 11(12): 2341. 2022Other
Haynes KA, et al. (2023) Rapid Single-Pot Assembly of Modular Chromatin Proteins for Epigenetic Engineering. Methods Mol Biol 2599:191-214. 2023Method development
Piel S, et al. (2022) Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning. Sci Rep 12(1):20329. 2022Mitochondrial studies
Idrees M, et al. (2022) Cycloastragenol activation of Telomerase improves β-Klotho protein level and attenuates age-related malfunctioning in ovarian tissues. Mech Ageing Dev Nov 30 doi: 10.1016/j.mad.2022.111756. 2022Other
Pan B, et al. (2022) MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1. Cell Death Discov 8(1):470. 2022Other
Duan X, et al. (2022) Novel Loss of Function (G15D) Mutation on RAC2 in a Family with Combined Immunodeficiency and Increased Levels of Immunoglobulin G, A, and E. J Clin Immunol Dec 2 doi: 10.1007/s10875-022-01411-5.2022Other
Kim J, et al. (2022) One‐step Preparation of an Injectable Hydrogel Scaffold System Capable of Sequential Dual‐growth Factor Release to Maximize Bone Regeneration. Adv Healthc Mater Dec 1 doi: 10.1002/adhm.202202401. 2022Stem cells
Ekundayo B, et al. (2022) Structural insights into the regulation of Cas7-11 by TPR-CHAT. Nat Struct Mol Biol Dec 5 doi: 10.1038/s41594-022-00894-5. 2022Structural biology/protein interactions
Nguyen H, et al. (2023) Impact of physiological media and sterilization methods on the physicochemical characteristics of engineered CNCs, and the effects on nanomaterial-protein interactions and immunological activity. Colloid Interface Sci Commun 52: 100684. 2023Structural biology/protein interactions
Reguigui A, et al. (2022) Nine-dimensional bioprofiles of Tunisian sages (Salvia officinalis, S. aegyptiaca and S. verbenaca) by high-performance thin-layer chromatography–effect-directed analyses. J Chromatogr A Dec 7 doi: 10.1016/j.chroma.2022.463704. 2022Plant sciences
Ceccacci S, et al. (2022) Jasminum sambac Cell Extract as Antioxidant Booster against Skin Aging. Antioxidants 11(12): 2409. 2022Other
Cheng D, et al. (2022) Emodin Alleviates Arthritis Pain through Reducing Spinal Inflammation and Oxidative Stress. Mol Pain Dec 6 doi: 10.1177/17448069221146398.2022Other
Beker M, et al. (2022) Dual action of exosomes derived from in vitro Aβ toxicity model: the role of age for pathological response. Arch Gerontol Geriatr 106:104874. 2022Neurobiology
Barilli A, et al. (2022) Growth Arrest of Alveolar Cells in Response to Cytokines from Spike S1-Activated Macrophages: Role of IFN-γ. Biomedicines 10 3085. 2022Cell signaling
Yoon SH, et al. (2022) Comparative study of lung toxicity of E-cigarette ingredients to investigate E-cigarette or Vaping Product associated Lung Injury. J Hazard Mater 445: 130454. 2022Other
Chen X, et al. (2022) Liensinine, an Isoquinoline-Type Alkaloid in Lotus Seeds, Suppressed TGF-beta1-Induced Proliferation and Migration in Human Tenon Capsule Fibroblast Cells Through MAP3K7 Gene. Rev. Bras. Farmacogn Dec 6 doi: 10.1007/s43450-022-00334-x. 2022Cell signaling
Vetrovoy O, et al. (2022) Prenatal Hypoxia-Induced Adverse Reaction to Mild Stress is Associated with Depressive-Like Changes in the Glucocorticoid System of Rats. Neurochem Res Dec 10 doi: 10.1007/s11064-022-03837-0. 2022Neurobiology
Senthilvelan A, et al. (2022) Click-iT Trinucleotide Cap Analog: Synthesis, mRNA Translation, and Detection. Bioorg Med Chem 77:117128. 2022Method development
Shao W, et al. (2022) Expression of fibrinogen-like protein 2 (Fgl2) on Toll-like receptor 9 (TLR9) expression in autoimmune myelitis. Int Immunopharmacol 114:109539. 2022Cell signaling
Yang W, et al. (2022) Thermophilic archaeon orchestrates temporal expression of GDGT ring synthases in response to temperature and acidity stress. Environ Microbiol Dec 10 doi: 10.1111/1462-2920.16301. 2022Microorganisms and model organisms
Digby EM, et al. (2022) Photocaged DNA-Binding Photosensitizer Enables Photocontrol of Nuclear Entry for Dual-Targeted Photodynamic Therapy. J Med Chem 65(24):16679-16694.2022Drug mechanism
Ji M, et al. (2022) Sirt6 attenuates chondrocyte senescence and osteoarthritis progression. Nat Commun 13(1):7658.2022Cell signaling
Singh S, et al. (2022) Butyrate Ameliorates Intraocular Bacterial Infection by Promoting Autophagy and Attenuating the Inflammatory Response. Infect Immun Dec 14 doi: 10.1128/iai.00252-22. 2022Cell signaling
Smart K, et al. (2022) Fidgetin-like 2 depletion enhances cell migration by regulating GEF-H1, RhoA, and FAK. Biophys J Dec 15 doi: 10.1016/j.bpj.2022.12.018.2022Other
Wang YF, et al. (2022) Endoplasmic reticulum stress regulates autophagic response that is involved in Saikosaponin a-induced liver cell damage. Toxicol In Vitro Dec 17 doi: 10.1016/j.tiv.2022.105534. 2022Other
Yang M, et al. (2022) Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surface. BMC Ophthalmol 22(1):490. 2022Neurobiology
Niwa R, et ail (2022) Experimental model of micronodular thymic neoplasm with lymphoid stroma. Thorac Cancer Dec 16 doi: 10.1111/1759-7714.14716. 2022Cancer studiesGeneral
Chen Y, et al. (2022) E2F1-mediated up-regulation of TOP2A promotes viability, migration, and invasion, and inhibits apoptosis of gastric cancer cells. J Biosci 47:84. 2022Cancer studiesGastric cancer
Degnan RM, et al. (2022) Exogenous double‐stranded RNA inhibits the infection physiology of rust fungi to reduce symptoms in planta. Mol Plant Pathol Dec 17 doi: 10.1111/mpp.13286. 2022Plant sciences
Luan Y, et al. (2022) TAp63 determines the fate of oocytes against DNA damage. Sci Adv 8(51):eade1846. 2022Cell signaling
Lee HL, et al. (2023) Anti-Amnesic Effect of Synbiotic Supplementation Containing Corni fructus and Limosilactobacillus reuteri in DSS-Induced Colitis Mice. Int Mol Sci 24(1):90. 2023Other
Yan Y, et al. (2022) Thalamocortical Circuit Controls Neuropathic Pain via Up-regulation of HCN2 in the Ventral Posterolateral Thalamus. Neurosci Bull Dec 20 doi: 10.1007/s12264-022-00989-5. 2022Neurobiology
Okawa M, et al. (2022) Extracellular matrix-inspired hydrogel of hyaluronan and gelatin crosslinked via a Link module with a transglutaminase reactive sequence. Commun Mater 3: 81. 2022Other
Jousma J, et al. (2022) Alteration of the N6-methyladenosine epitranscriptomic profile in synthetic phthalate-treated human induced pluripotent stem cell-derived endothelial cells. Epigenomics Oct 31 doi: 10.2217/epi-2022-0110.2022Disease studyBiomarker research
Liang W, et al. (2022) Prolactin-Induced Protein facilitates corneal wound healing. Exp Eye Res 225:109300. 2022Other
Dong ZB, et al. (2022) 2-Bromopalmitate decreases spinal inflammation and attenuates oxaliplatin-induced neuropathic pain via reducing Drp1-mediated mitochondrial dysfunction. PLoS One 17(10):e0275428. 2022Cancer studiesGeneral
Wang TC, et al. (2022) Inflammation-Regulated Nanodrug Sensitizes Hepatocellular Carcinoma to Checkpoint Blockade Therapy by Reprogramming the Tumor Microenvironment. ACS Appl Mater Interfaces Oct 31 doi: 10.1021/acsami.2c14448.2022Cancer studiesLiver cancer
Wu Z, et al. (2022) ALDH3B1 protects interfollicular epidermal cells against lipid peroxidation via the NRF2 pathway. Cell Stress Chaperones Nov 3 doi: 10.1007/s12192-022-01306-9. 2022Cell signaling
Qu X, et al. (2022) Solamargine Alleviates Proliferation and Metastasis of Cervical Cancer Cells by Blocking the CXCL3-Mediated Erk Signaling Pathway. Evid Based Complement Alternat Med Oct 29 doi: 10.1155/2022/7634754. 2022Cancer studiesGeneral
Liu L, et al. (2022) Fibroblast growth factor 10 protects against particulate matter-induced lung injury by inhibiting oxidative stress-mediated pyroptosis via the PI3K/Akt/Nrf2 signaling pathway. Int Immunol 113: 109398. 2022Cell signaling
Chrystal PW, et al. (2022) The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision. Nat Commun 13(1):6595. 2022Other
Cameron DR, et al. (2022) Parallel Evolution of Pseudomonas aeruginosa during a Prolonged ICU-Infection Outbreak. Microbiol Spectr Nov 7 doi: 10.1128/spectrum.02743-22. 2022Microorganisms and model organisms
Martinez P, et al. (2022) Bassoon contributes to tau-seed propagation and neurotoxicity. Nat Neurosci Nov 7 doi: 10.1038/s41593-022-01191-6. 2022Neurobiology
Li Z, et al. (2022) Xuanfei Baidu Formula alleviates impaired mitochondrial dynamics and activated NLRP3 inflammasome by repressing NF-κB and MAPK pathways in LPS-induced ALI and inflammation models. Phytomedicine Nov 9 doi: 10.1016/j.phymed.2022.154545. 2022Mitochondrial studies
Nanduri B, et al. (2023) Using Activity-Based Proteomics for the Quantification of Deubiquitinases in Animal Tissue. Methods Mol Biol 2591:45-57. 2022Method development
Wang J, et al. (2022) Nuclear paraspeckle assembly transcript 1 promotes the podocyte injury via targeting miR-23b-3p/B-cell lymphoma-2 interacting protein 3 like axis. Ren Fail 44(1):1961-1975. 2022Other
Spetz JKE, et al. (2022) Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy–induced toxicities. Sci Adv 8(45):eabn6579. 2022Cancer studiesGeneral
Hepowit NL, et al. (2023) Application of Archaea in Deubiquitinase-Like Enzyme Discovery and Activity Assay. Methods Mol Biol 2591:151-169. 2022Method development
Kim H, et al. (2022) Afrormosin exerts an anticancer effect via MAPK and AKT signaling pathways in B16F10 cells. Appl Biol Chem 65 71. 2022Cancer studiesSkin cancer
Song J, et al. (2022) Matrix Adhesiveness Regulates Myofibroblast Differentiation from Vocal Fold Fibroblasts in a Bio-orthogonally Cross-linked Hydrogel. ACS Appl Mater Interfaces 14(46):51669-51682. 2022Other
Xenias HS, et al. (2022) R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations. Commun Biol 5(1):1211. 2022Other
Benoit M, et al. (2022) Postnatal neuronal Bace1 deletion impairs neuroblast and oligodendrocyte maturation. Hum Mol Genet Nov 12 doi: 10.1093/hmg/ddac282.2022Other
Joo S, et al. (2022) α-ketoglutarate suppresses immediate early gene expression in cancer cells. Biochem Biophys Res Commun 637:144-152. 2022Cancer studiesGeneral
Jacob C, et al. (2022) Mediterranean G6PD variant mitigates expression of DNA methyltransferases and right heart pressure in experimental model of pulmonary hypertension. J Biol Chem Nov 10 doi: 10.1016/j.jbc.2022.102691. 2022Other
Liu Y, et al. (2022) Melatonin alleviates heat stress-induced testicular damage in dairy goats by inhibiting the PI3K/AKT signaling pathway. Stress Biology 2: 47. 2022Cell signaling
Liu X, et al. (2022) CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition. Cancer Cell 40(11):1341-1357. 2022Cancer studiesBreast cancer
Sridaran D, et al. (2022) Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance. Nat Commun 13(1):6929. 2022Cancer studiesGeneral
Park SH, et al. (2022) Inositol polyphosphates‐regulated polyubiquitination of PHR1 by NLA E3 ligase during phosphate starvation response in Arabidopsis. New Phytol Nov 14 doi: 10.1111/nph.18621.2022Plant sciences
Feng Y, et al. (2022) Promotion of osteogenesis in BMSC under hypoxia by ATF4 via the PERK–eIF2α signaling pathway. In Vitro Cell Dev Biol Anim Nov 15 doi: 10.1007/s11626-022-00732-4.2022Cell signaling
Guidry G, et al. (2022) 17β-estradiol ameliorates delirium-like phenotypes in a murine model of urinary tract infection. Sci Rep 12(1):19622. 2022Neurobiology
Xu M, et al. (2022) Alteration in tyrosine phosphorylation of cardiac proteome and EGFR pathway contribute to hypertrophic cardiomyopathy. Commun Biol 5(1):1251. 2022Disease studyBiomarker research
Shin E, et al. (2022) LDR-adapted liver-derived cytokines have potential to induce atherosclerosis. Int J Radiat Biol Nov 16 doi: 10.1080/09553002.2023.2145028. 2022Other
Sheriff A, et al. (2022) ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation. Sci Rep 12(1):19643. 2022DNA repair process
Hong SC, et al. (2022) Protective effect of Tisochrysis lutea on dry eye syndrome via NF-κB inhibition. Sci Rep 12(1):19576.2022Other
Zhang N, et al. (2022) LCMT1 indicates poor prognosis and is essential for cell proliferation in hepatocellular carcinoma. Transl Oncol 27:101572. 2022Cancer studiesLiver cancer
Wu HF, et al. (2022) Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models. Nat Commun 13(1):7032. 2022Neurobiology
Jamshidi-adegani F, et al. (2022) Comparative study of the cytotoxicity, apoptotic, and epigenetic effects of Boswellic acid derivatives on breast cancer. Sci Rep 12(1):19979. 2022Cancer studiesBreast cancer
Wang HC, et al. (2022) Tumor-associated macrophages promote resistance of hepatocellular carcinoma cells against sorafenib by activating CXCR2 signaling. J Biomed Sci 29(1):99. 2022Cancer studiesLiver cancer
Shin JY, et al. (2022) Priming mesenchymal stem cells with α-synuclein enhances neuroprotective properties through induction of autophagy in Parkinsonian models. Stem Cell Res Ther 13(1):483. 2022Neurobiology
Li W, et al. (2022) BdcSP10 is a prophenoloxidase-activating protease in Bactrocera dorsalis. Dev Comp Immunol 138:104558. 2022Other
Palmelund LB, et al. (2022) Development of a medium throughput whole-cell microtiter plate Thr286 autophosphorylation assay for CaMKIIα using ELISA. J Pharmacol Toxicol Methods 118:107226. 2022Method development
Menkhorst E, et al. (2022) Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia. Pregnancy Hypertens 30:130-136. 2022Cell signaling
Jovanović Stojanov S, et al. (2022) Autophagy Inhibition Enhances Anti-Glioblastoma Effects of Pyrazolo [3, 4-d] pyrimidine Tyrosine Kinase Inhibitors. Life 12(10):1503. 2022Cancer studiesBrain cancer
Chan KL, et al. (2022) Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses. Cancer Cell Sep 19 doi: 10.1016/j.ccell.2022.09.007. 2022Cancer studiesGeneral
Jana A, et al. (2022) Increased Type I interferon signaling and brain endothelial barrier dysfunction in an experimental model of Alzheimer's disease. Sci Rep 12(1):16488. 2022Neurobiology
Tatara M, et al. (2023) ATAC-Seq Analysis of Accessible Chromatin: From Experimental Steps to Data Analysis. Methods Mol Biol 2577:65-81. 2022Method development
Tran NL, et al. (2022) Facile Construction of Tumour Spheroids with Induced M2 Macrophage Polarization for Anticancer Drug Screening. Biomed Mater Sep 27 doi: 10.1088/1748-605X/ac956c. 2022Cancer studiesGeneral
Xiong X, et al. (2022) MicroRNA-34b-5p targets PPP1R11 to inhibit proliferation and promote apoptosis in cattleyak Sertoli cells by regulating specific signaling pathways. Theriogenology 194:46-57. 2022Cell signaling
Hsueh SC, et al. (2022) Activity of a Novel Anti-Inflammatory Agent F-3, 6′-dithiopomalidomide as a Treatment for Traumatic Brain Injury. Biomedicines  10(10):2449. 2022Neurobiology
Qrareya AN, et al. (2022) HIV-1 Tat Upregulates the Receptor for Advanced Glycation End Products and Superoxide Dismutase-2 in the Heart of Transgenic Mice. Viruses 14(10):2191. 2022Other
Chalise U, et al. (2022) Harnessing the Plasma Proteome to Mirror Current and Predict Future Cardiac Remodeling After Myocardial Infarction. J Cardiovasc Transl Res Oct 5 doi: 10.1007/s12265-022-10326-w. 2022Disease studyBiomarker research
Qin L, et al. (2022) The miR-21-5p enriched in the apoptotic bodies of M2 macrophage-derived extracellular vesicles alleviates osteoarthritis by inducing a change in the macrophage phenotype. Genes & Diseases Oct 5 doi: 10.1016/j.gendis.2022.09.010. 2022Other
Pellavio G, et al. (2022) Aquaporin-6 May Increase the Resistance to Oxidative Stress of Malignant Pleural Mesothelioma Cells. Cells 11(12):1892. 2022Cancer studiesLung cancer
Tramonti A, et al. (2022) Characterization of the Escherichia coli pyridoxal 5'‐phosphate homeostasis protein (YggS): role of lysine residues in PLP binding and protein stability. Protein Sci Oct 11 doi: 10.1002/pro.4471. 2022Structural biology/protein interactions
El Hamdaoui Y, et al. (2022) Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs. Mol Psychiatry Oct 12 doi: 10.1038/s41380-022-01804-3. 2022Neurobiology
Durand-de Cuttoli R, et al. (2022) Distinct forms of regret linked to resilience versus susceptibility to stress are regulated by region-specific CREB function in mice. Sci Adv 8(42):eadd5579. 2022Neurobiology
Mills C, et al. (2022) A Novel CRISPR Interference Effector Enabling Functional Gene Characterization with Synthetic Guide RNAs. CRISPR J Oct 17 doi: 10.1089/crispr.2022.0056. 2022CRISPR
Griem-Krey N, et al. (2022) The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction. Biomed Pharmacother 156:113895. 2022Neurobiology
Sun H, et al. (2022) Increased circulating microparticles contribute to severe infection and adverse outcomes of COVID-19 patients with diabetes. Am J Physiol Heart Circ Physiol Oct 21 doi: 10.1152/ajpheart.00409.2022. 2022Other
Choi W, et al. (2022) Targeted thrombolysis by magnetoacoustic particles in photothrombotic stroke model. Biomater Res 26(1):58. 2022Drug mechanism
Lu X, et al. (2022) Silencing SNHG1 Suppresses Viability, Proliferation and Invasion of Gallbladder Carcinoma Cells via Targeting miR-194-5p. Ann Clin Lab Sci 52(5):707-720. 2022Cancer studiesGeneral
Li Z, et al. (2022) Enhancing Gasdermin-induced tumor pyroptosis through preventing ESCRT-dependent cell membrane repair augments antitumor immune response. Nat Commun 13(1):6321. 2022Cancer studiesGeneral
Park JS, et al. (2022) Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein. Cell Rep 41(4):111545. 2022Structural biology/protein interactions
Zhou G, et al. (2022) Co-alterations of circadian clock gene transcripts in human placenta in preeclampsia. Sci Rep 12(1):17856. 2022Other
Cruz JA, et al. (2022) A pseudovirus-based platform to measure neutralizing antibodies in Mexico using SARS-CoV-2 as proof-of-concept. Sci Rep 12(1):17966. 2022Method development
Bergman H, et al. (2022) Establishment of Cytotoxic and Non-cytotoxic NK-92 Cell Clones–Evaluation of Their Function as Target Cells. Anticancer Res 42(9):4259-4264. 2022Cancer studiesGeneral
Okada C, et al. (2022) Establishment of Neutralizing Monoclonal Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 by the Screening with Exosomes Expressing the Viral Spike Protein. Monoclon Antib Immunodiagn Immunother (4):173-180.2022Method development
Cui S, et al. (2022) SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR. Acta Pharmaceutica Sinica B Aug 27 doi: 10.1016/j.apsb.2022.08.019.2022Other
Chen Y, et al. (2022) Tumour-associated Mucin1 correlates with the procoagulant properties of cancer cells of epithelial origin. Thrombosis Update 9: 100123. 2022Cancer studiesGeneral
Stenvall CGA, et al. (2022) Cytoplasmic keratins couple with and maintain nuclear envelope integrity in colonic epithelial cells. Mol Biol Cell Aug 24 doi: 10.1091/mbc.E20-06-0387. 2022Structural biology/protein interactions
Ju P, et al. (2022) Histone deacetylase 4 inhibition ameliorates the social deficits induced by Ephrin-B2 mutation. Prog Neuropsychopharmacol Biol Psychiatry Aug 24 doi: 10.1016/j.pnpbp.2022.110622. 2022Neurobiology
Spampinato SF, et al. (2022) Microglia Contributes to BAF-312 Effects on Blood–Brain Barrier Stability. Biomolecules 12(9): 1174. 2022Neurobiology
Pritchard Jr KA, et al. (2022) Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia. PLoS One 17(8):e0269564. 2022Other
Zhang G, et al. (2022) ACOT7 protects epidermal stem cells against lipid peroxidation. In Vitro Cell Dev Biol Anim Aug 29 doi: 10.1007/s11626-022-00703-9.2022Other
Yin J, et al. (2022) Development of Whole-Cell Biosensors for Screening of Peptidoglycan-Targeting Antibiotics in a Gram-Negative Bacterium. Appl Environ Microbiol Aug 30 doi: 10.1128/aem.00846-22. 2022Method development
Han Z, et. al. (2022) Hsp20 Promotes Endothelial Progenitor Cell Angiogenesis via Activation of PI3K/Akt Signaling Pathway under Hypoxia. Tissue Eng Regen Med Aug 30 doi: 10.1007/s13770-022-00481-1. 2022Cell signaling
Basu S, et al. (2022) Negative Feedback Loop Mechanism between EAF1/2 and DBC1 in Regulating ELL Stability and Functions. Mol Cell Biol Aug 29 doi: 10.1128/mcb.00151-22. 2022Structural biology/protein interactions
López‐Haber C, et al. (2022) The phagosomal solute transporter SLC15A4 promotes inflammasome activity via mTORC1 signaling and autophagy restraint in dendritic cells. EMBO J Aug 29 doi: 10.15252/embj.2022111161. 2022Other
Fowler EW, et al. (2022) A TGFβR inhibitor represses keratin-7 expression in 3D cultures of human salivary gland progenitor cells. Sci Rep 12(1):15008. 2022Stem cells
Kuppa S, et al. (2022) Rtt105 regulates RPA function by configurationally stapling the flexible domains. Nat Commun 13(1):5152. 2022DNA repair process
Sawai M, et al. (2022) Dihydropyrazine suppresses TLR4-dependent inflammatory responses by blocking MAPK signaling in human hepatoma HepG2 cells. J Toxicol Sci 47(9):381-387. 2022Cell signaling
Jin N, et al. (2022) Tau seeding activity in various regions of down syndrome brain assessed by two novel assays. Acta Neuropathol Commun 10(1):132. 2022Neurobiology
Shen H, et al. (2022) TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination. Eye Vis (Lond) 9(1):35. 2022Other
Gerhardy S, et al. (2022) Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration. Nat Commun 13(1):5222.2022Structural biology/protein interactions
Tiwari R, et al. (2022) Chemical inhibition of oxygen-sensing prolyl hydroxylases impairs angiogenic competence of human vascular endothelium through metabolic reprogramming. iScience Sep 6 doi: 10.1016/j.isci.2022.105086. 2022Other
Shi H, et al. (2022) Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia. Acta Neuropathol Commun 10(1):136.2022Neurobiology
Visigalli R, et al. (2022) Expression and Function of ABC Transporters in Human Alveolar Epithelial Cells. Biomolecules 12(9):1260.2022Other
Schon SB, et al. (2022) Obesity-related alterations in protein expression in human follicular fluid from women undergoing in-vitro fertilization (IVF). F S Sci Sep 9 doi: 10.1016/j.xfss.2022.09.002.2022Disease studyBiomarker research
Yoon JY, et al. (2022) Chemically-induced osteogenic cells for bone tissue engineering and disease modeling. Biomaterials 289:121792. 2022Method development
Jang M, et al. (2022) Hyperglycemic Neurovasculature‐On‐A‐Chip to Study the Effect of SIRT1‐Targeted Therapy for the Type 3 Diabetes “Alzheimer's Disease”. Adv Sci (Weinh) Sep 8 doi: 10.1002/advs.202201882. 2022Neurobiology
Xue H, et al. (2022) A two-step mechanism governing PARP1-DNA retention by PARP inhibitors. Sci Adv 8(36):eabq0414. 2022DNA repair process
Dai X, et al. (2022) KLF5-mediated aquaporin 3 activated autophagy to facilitate cisplatin resistance of gastric cancer. Immunopharmacol Immunotoxicol Sep 20 doi: 10.1080/08923973.2022.2122498. 2022Cancer studiesGastric cancer
van Senten JR, et al. (2022) Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in mGlu5a receptor internalization. J Biol Chem Sep 7 doi: 10.1016/j.jbc.2022.102466. 2022CRISPR
Mallard J, et al. (2022) Development of skeletal muscle atrophy and intermuscular adipose tissue in early breast cancer patients treated with chemotherapy. Am J Physiol Cell Physiol Sep 12 doi: 10.1152/ajpcell.00373.2022. 2022Cancer studiesBreast cancer
Uquillas JA, et al. (2022) An off-the-shelf decellularized and sterilized human bone-ACL-bone allograft for anterior cruciate ligament reconstruction. J Mech Behav Biomed Mater 135:105452. 2022Other
Song W and Qiu N (2022) MiR-495-3p depletion contributes to myocardial ischemia/reperfusion injury in cardiomyocytes by targeting TNC. Regen Ther 21: 380-388. 2022Other
Kane EI, et al. (2022) Redefining the Catalytic HECT Domain Boundaries for the HECT E3 Ubiquitin Ligase Family. Biosci Rep Sep 16 doi: 10.1042/BSR20221036. 2022Structural biology/protein interactions
Zhang N, et al. (2022) Ameliorative effect of Lactobacillus plantarum Lp2 against cyclophosphamide-induced liver injury in mice. Food Chem Toxicol 169:113433. 2022Cell signaling
Wang S, et al. (2022) Ginseng polysaccharide attenuates red blood cells oxidative stress injury by regulating red blood cells glycolysis and liver gluconeogenesis. J Ethnopharmacol 300:115716.2022Other
Fonseca-Ornelas L, et al. (2022) Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neurons. NPJ Parkinsons Dis 8(1):118. 2022Neurobiology
Barilli A, et al. (2022) The JAK1/2 Inhibitor Baricitinib Mitigates the Spike-Induced Inflammatory Response of Immune and Endothelial Cells In Vitro. Biomedicines 10(9):2324. 2022Cell signaling
Zhu X, et al. (2022) Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. Nat Commun 13(1):5513.2022Structural biology/protein interactions
Lim KM, et al. (2022) Advanced 3D Dynamic Culture System with Transforming Growth Factor-β3 Enhances Production of Potent Extracellular Vesicles with Modified Protein Cargoes via Upregulation of TGF-β Signaling. J Adv Res Sep 18 doi: 10.1016/j.jare.2022.09.005.2022Method development
Huang Y, et al. (2022) Intracellular delivery of messenger RNA to macrophages with surfactant-derived lipid nanoparticles. Mater Today Adv 16: 100295. 2022Method development
Katifelis H, et al. (2022) Amniotic Fluid-Derived Mesenchymal Stem/Stromal Cell-Derived Secretome and Exosomes Improve Inflammation in Human Intestinal Subepithelial Myofibroblasts. Biomedicines 10(10): 2357. 2022Stem cells
Hauvermale AL, et al. (2022) GA signaling expands: the Plant UBX domain-containing protein 1 is a binding partner for the GA receptor. Plant Physiol Sep 23 doi: 10.1093/plphys/kiac406. 2022Plant sciences
Donne R, et al. (2022) Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD. Dev Cell Jun 23 doi: 10.1016/j.devcel.2022.06.003.2022DNA repair process
Stewart JA, et al. (2022) A redox-sensitive iron-sulfur cluster in murine FAM72A controls its ability to degrade the nuclear form of uracil-DNA glycosylase. DNA Repair (Amst) 118:103381. 2022DNA repair process
Watkins JM, et al. (2022) An Engineered Monovalent Anti–TNF-α Antibody with pH-Sensitive Binding Abrogates Immunogenicity in Mice following a Single Intravenous Dose. J Immunol Jul 27 doi: 10.4049/jimmunol.2101180. 2022Other
Armstrong Z, et al. (2022) Cryo-EM structures of human fucosidase FucA1 reveal insight into substrate recognition and catalysis. Structure Jul 19 doi: 10.1016/j.str.2022.07.001. 2022Structural biology/protein interactions
Schlegel C, et al. (2022) Decreased expression of hypoxia-inducible factor 1α (HIF-1α) in cord blood monocytes under anoxia. Pediatr Res Jul 29 doi: 10.1038/s41390-022-02193-7. 2022Cell signaling
Crudele A, et al. (2022) Hydroxytyrosol Recovers SARS-CoV-2-PLpro-Dependent Impairment of Interferon Related Genes in Polarized Human Airway, Intestinal and Liver Epithelial Cells. Antioxidants 11(8):1466. 2022Other
Fischer JA, et al. (2022) Opposing effects of genetic variation in MTCH2 for obesity versus heart failure. Hum Mol Genet Jul 29 doi: 10.1093/hmg/ddac176.2022Disease studyBiomarker research
Hasegawa M, et al. (2022) Tumor suppressor effect of an antibody on xenotransplanted sarcomatoid mesothelioma cells. Thorac Cancer Aug 2 doi: 10.1111/1759-7714.14591. 2022Cancer studiesGeneral
Wang S, et al. (2022) Huanglian ointment alleviates eczema by maintaining the balance of c-Jun and JunB and inhibiting AGE-RAGE-mediated pro-inflammation signaling pathway. Phytomedicine 105:154372.2022Cell signaling
Zhi Y, et al. (2022) The effects of air pollutants exposure on the transmission and severity of invasive infection caused by an opportunistic pathogen Streptococcus pyogenes. Environ Pollut Aug 3 doi: 10.1016/j.envpol.2022.119826. 2022Microorganisms and model organisms
Kolhe P, et al. (2022) Fabrication of an ultrasensitive electrochemical immunosensor coupled with biofunctionalized zero-dimensional graphene quantum dots for rapid detection of cephalexin. Food Chemistry 398:133846. 2022Method development
Nelczyk AT, et al. (2022) The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple-negative breast cancer. Biochim Biophys Acta Mol Basis Dis Aug 3 doi: 10.1016/j.bbadis.2022.166515. 2022Cancer studiesBreast cancer
Leng F, et al. (2022) The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis. Immunity 55(8):1354-1369.e8. 2022Structural biology/protein interactions
Eccardt AM, et al. (2022) Stimulation of Akt Phosphorylation and Glucose Transport by Metalloporphyrins with Peroxynitrite Decomposition Catalytic Activity. Catalysts 12(8):849.2022Cell signaling
El-Sayed D, et al. (2022) Evaluating the Phenotypic and Genomic Characterization of Some Egyptian Phages Infecting Shiga Toxin-Producing Escherichia coli O157: H7 for the Prospective Application in Food Bio-Preservation. Biology 11(8)1180.2022Microorganisms and model organisms
Costa TC, et al. (2022) Ruminal undegradable protein enriched diet during late gestation of beef cows affects maternal metabolism and offspring's skeletal muscle development. Anim Feed Sci Technol 291:115400. 2022Other
Metformin improves depressive-like behavior in experimental Parkinson's disease by inducing autophagy in the substantia nigra and hippocampus. Inflammopharmacology Aug 6 doi: 10.1007/s10787-022-01043-6.2022Neurobiology
Sherlock D. and Fogg PCM. (2022) The archetypal gene transfer agent RcGTA is regulated via direct interaction with the enigmatic RNA polymerase omega subunit. Cell Rep 40(6):111183. 2022Other
Desjardins CA, et al. (2022) Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice. Nucleic Acids Res Aug 10 doi: 10.1093/nar/gkac641. 2022Neurobiology
Emdal KB, et al. (2022) Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance. Cell Rep 40(6):111177. 2022Neurobiology
Dupont V, et al. (2022) Impaired renal reserve contributes to preeclampsia via the kynurenine and soluble fms-like tyrosine kinase 1 pathway. J Clin Invest Aug 9 doi: 10.1172/JCI158346. 2022Cell signaling
Guo X, et al. (2022) Vasorin contributes to lung injury via FABP4-mediated inflammation. Mol Biol Rep Aug 10 doi: 10.1007/s11033-022-07780-9.2022Other
Lopes FBTP, et al. (2022) Temporal and sex-linked protein expression dynamics in a familial model of Alzheimer's Disease. Mol Cell Proteomics Aug 6 doi: 10.1016/j.mcpro.2022.100280. 2022Neurobiology
Gatticchi L, et al. (2022) CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1. Biochimie Aug 11 doi: 10.1016/j.biochi.2022.08.005. 2022CRISPR
Lazcano P, et al. (2022) Phosphatidic acid inhibits inositol synthesis by inducing nuclear translocation of kinase IP6K1 and repression of myo-inositol-3-P synthase. J Biol Chem Aug 10 doi: 10.1016/j.jbc.2022.102363. 2022Cell signaling
D'Acunzo P, et al. (2022) Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues. Nat Protoc Aug 12. doi: 10.1038/s41596-022-00719-1.2022Method development
H Fu, et al. (2023) The heated-induced gelation of soy protein isolate at subunit level: Exploring the impacts of α and α′ subunits on SPI gelation based on natural hybrid breeding varieties. Food Hydrocolloids doi: 10.1016/j.foodhyd.2022.108008. 2022Plant sciences
Xu Q, et al. (2022) CircSERPINA3 promoted cell proliferation, migration, and invasion of laryngeal squamous cell carcinoma by targeting miR‐885‐5p. Cell Biol Int Aug 16 doi: 10.1002/cbin.11872. 2022Cancer studiesSquamous cell carcinoma
Tachibana N, et al. (2022) RSPO2 defines a distinct undifferentiated progenitor in the tendon/ligament and suppresses ectopic ossification. Sci Adv 8(33):eabn2138. 2022Other
Kushwaha A, et al. (2022) Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl) homoserine lactone induces calcium signaling-dependent crosstalk between autophagy and apoptosis in human macrophages. Cell Signal 99:110441.2022Cell signaling
Zafferani M, et al. (2022) Multiassay Profiling of a Focused Small Molecule Library Reveals Predictive Bidirectional Modulation of the lncRNA MALAT1 Triplex Stability In Vitro. ACS Chem Biol Aug 19 doi: 10.1021/acschembio.2c00124. 2022Method development
Pozzi S, et al. (2022) MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression. JCI Insight Aug 18 doi: 10.1172/jci.insight.154804. 2022Cancer studiesBrain cancer
Jia H, et al. (2022) Highly efficient and simple SSPER and rrPCR approaches for the accurate site-directed mutagenesis of large and small plasmids. N Biotechnol Aug 22 doi: 10.1016/j.nbt.2022.08.004.2022Method development
Mukherjee D, et al. (2022) Fetal pulmonary hypertension: dysregulated microRNA-34c-Notch1 axis contributes to impaired angiogenesis in an ovine model. Pediatr Res Jun 18 doi: 10.1038/s41390-022-02151-3. 2022Other
Zhang D, et al. (2022) Upregulation of miR‐144‐3p alleviates Doxorubicin‐induced heart failure and cardiomyocytes apoptosis via SOCS2/PI3K/AKT axis. Chem Biol Drug Des Jun 22. doi: 10.1111/cbdd.14104. 2022Cell signaling
He J, et al. (2022) Ruscogenin Ameliorated Sjögren's Syndrome by Inhibiting NLRP3 Inflammasome Activation. Evid Based Complement Alternat Med Jun 28 doi: 10.1155/2022/6425121. 2022Cell signaling
Fang CL, et al. (2022) Angelica dahurica attenuates melanogenesis in B16F0 cells by repressing Wnt/β-catenin signaling. Mol. Cell. Toxicol June 27 doi: 10.1007/s13273-022-00250-0. 2022Other
Mohamed ISE, et al. (2022) Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo. Pharmaceutics 14(6):1173. 2022Cancer studiesSkin cancer
Lee EH, et al. (2022) Inhibition of TRPM7 suppresses migration and invasion of prostate cancer cells via inactivation of ERK1/2, Src and Akt pathway signaling. J. Mens Health 18(7):144. 2022Cancer studiesGeneral
Kim JH, et al. (2022) Increasing the resilience of plant immunity to a warming climate. Nature Jun 29 doi: 10.1038/s41586-022-04902-y. 2022Plant sciences
Marcovich I, et al. (2033) Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11. Biomolecules 12(7): 914. 2022Method development
Porcù E, et al. (2022) Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration. Transl Res Jul 1 doi: 10.1016/j.trsl.2022.06.017. 2022Cancer studiesBrain cancer
Park SK, et al. (2022) Porphyra tenera Protects against PM2. 5-Induced Cognitive Dysfunction with the Regulation of Gut Function. Mar. Drugs 20(7):439. 2022Neurobiology
Avila H, et al. (2022) Hydra-Elastin-like Polypeptides Increase Rapamycin Potency When Targeting Cell Surface GRP78. Biomacromolecules Jul 5 doi: 10.1021/acs.biomac.2c00048. 2022Drug mechanism
Han SM, et al. (2022) The Change in Circadian Rhythms in P301S Transgenic Mice is Linked to Variability in Hsp70-related Tau Disaggregation. Exp Neurobiol 31(3):196-207. 2022Neurobiology
Li Z, et al. (2022) Sodium para-aminosalicylic acid ameliorates lead-induced hippocampal neuronal apoptosis by suppressing the activation of the IP3R-Ca2+-ASK1-p38 signaling pathway. Ecotoxicol Environ Saf 241:113829. 2022Neurobiology
Pemberton K, et al. (2022) Differential Effects of the G Protein-Coupled Estrogen Receptor (GPER) on Rat Embryonic (E18) Hippocampal and Cortical Neurons. eNeuro Jun 30 doi: 10.1523/ENEURO.0475-21.2022. 2022Neurobiology
Poli E, et al. (2022) Immunoreactivity against fibroblast growth factor 8 in alveolar rhabdomyosarcoma patients and its involvement in tumor aggressiveness. Oncoimmunology 11(1):2096349. 2022Cancer studiesGeneral
Baglyas M, et al. (2022) High-performance thin-layer chromatography-antibacterial assay first reveals bioactive clerodane diterpenes in giant goldenrod (Solidago gigantea Ait.). J Chromatogr A July 9 doi: 10.1016/j.chroma.2022.463308. 2022Plant sciences
Chu HS, et al. (2022) Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production. Invest Ophthalmol Vis Sci 63(8):1. 2022Cell signaling
Swain RM, et al. (2022) Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines. Invest New Drugs Jul 6 doi: 10.1007/s10637-022-01266-y. 2022Cancer studiesGeneral
Wu LK, et al. (2022) Artemisia Leaf Extract protects against neuron toxicity by TRPML1 activation and promoting autophagy/mitophagy clearance in both in vitro and in vivo models of MPP+ and MPTP induced Parkinson’s disease. Phytomedicine 104:154250. 2022Neurobiology
Shahdeo D, et al. (2022) Graphene-Based Field-Effect Transistor for Ultrasensitive Immunosensing of SARS-CoV-2 Spike S1 Antigen. ACS Appl Bio Mater 5(7):3563-3572. 2022Method development
Duschmalé J, et al. (2022) Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers. Mol Ther Nucleic Acids 29:176-188.2022Method development
Hu F, et al. (2022) Bioinformatics analysis of KLF2 as a potential prognostic factor in ccRCC and association with epithelial‑mesenchymal transition. Exp Ther Med 24:561. 2022Cancer studiesGeneral
Halle JL, et al. (2022) Short duration treadmill exercise improves physical function and skeletal muscle mitochondria protein expression after recovery from FOLFOX chemotherapy in male mice. FASEB J 36(8):e22437. 2022Mitochondrial studies
Weinheimer AS, et al. (2022) Extended DNA binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks. J Biol Chem Jul 15 doi: 10.1016/j.jbc.2022.102268.2022DNA repair process
Guleria VS, et al. (2022) The intraflagellar transport protein IFT52 associated with short-rib thoracic dysplasia is essential for ciliary function in osteogenic differentiation in vitro and for sensory perception in Drosophila. Exp Cell Res 418(2):113273.2022Neurobiology
Qin W, et al. (2022) Osteoglycin (OGN) promotes tumorigenesis of pancreatic cancer cell via targeting ID4. Tissue and Cell July 16 doi: 10.1016/j.tice.2022.101867. 2022Cancer studiesPancreatic cancer
Ye Z, et al. (2022) LMCD1 facilitates the induction of pluripotency via cell proliferation, metabolism, and epithelial‐mesenchymal transition. Cell Biol Int Jul 16 doi: 10.1002/cbin.11858. 2022Other
Demonbreun AR, et al. (2022) A conserved annexin A6–mediated membrane repair mechanism in muscle, heart, and nerve. JCI Insight 7(14):e158107. 2022Neurobiology
Singh N, et al. (2022) Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance. Sci Adv 8(29):eabo3610. 2022Neurobiology
Wang Z, et al. (2022) The N6-methyladenosine writer WTAP contributes to the induction of immune tolerance post kidney transplantation by targeting regulatory T cells. Lab Invest Jul 21 doi: 10.1038/s41374-022-00811-w. 2022Other
Simeone CA, et al. (2022) A dominant negative ADIPOQ mutation in a diabetic family with renal disease, hypoadiponectinemia, and hyperceramidemia. NPJ Genom Med 7(1):43. 2022Disease studyBiomarker research
Dong ZB, et al. (2022) Resveratrol ameliorates oxaliplatin‑induced neuropathic pain via anti‑inflammatory effects in rats. Exp Ther Med July 21 doi: 10.3892/etm.2022.11523.2022Neurobiology
Zhang L, et al. (2022) Measuring Cytological Proximity of Chromosomal Loci to Defined Nuclear Compartments with TSA-seq. Methods Mol Biol 2532:145-186. 2022Method development
Song D, et al. (2022) Dual-hairpin ligation amplification enabled ultra-sensitive and selective ATP detection for cancer monitor. Biosens Bioelectron 212:114402. 2022Other
John L, et al. (2022) Redirecting Imipramine against Bluetongue Virus Infection: Insights from a Genome-wide Haploid Screening Study. Pathogens 11(5):602.2022Other
Du Q, et al. (2022) Bioinformatics analysis of LMAN1 expression, clinical characteristics, and its effects on cell proliferation and invasion in glioma. Brain Res 1789:147952.2022Cancer studiesBrain cancer
Grismaldo Rodríguez A, et al. (2022) Effect of Platelet-Derived Growth Factor C on Mitochondrial Oxidative Stress Induced by High d-Glucose in Human Aortic Endothelial Cells. Pharmaceuticals (Basel) 15(5):639.2022Cell signaling
Simões V, et al. (2022) Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes. Cell Rep 39(8):110860. 2022Other
Altegoer F, et al. (2022) Structural insights into the mechanism of archaellar rotational switching. Nat Commun 13(1):2857.2022Structural biology/protein interactions
Gangopadhyay A, et al. (2022) NLRP3 licenses NLRP11 for inflammasome activation in human macrophages. Nat Immunol 23(6):892-903.2022Cell signaling
Roy S, et al. (2022) Role of MrgprB2 in Rosacea-like Inflammation in Mice: Modulation by βarrestin2. J Invest Dermatol May 26 doi: 10.1016/j.jid.2022.05.005. 2022Cell signaling
Matyushkina D, et al. (2022) Autoimmune Effect of Antibodies against the SARS-CoV-2 Nucleoprotein. Viruses 14(6): 1141. 2022Microorganisms and model organisms
Zhang Q, et al. (2022) Down-Regulating Scar Formation by Microneedles Directly via a Mechanical Communication Pathway. ACS Nano May 26 doi: 10.1021/acsnano.1c11016. 2022Method development
Lin S, et al. (2022) TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis. Cell Commun Signal 20(1):75. 2022Cell signaling
Fan X, et al. (2022) Iron-Regulated Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery. J Biol Chem May 30 doi: 10.1016/j.jbc.2022.102094. 2022Structural biology/protein interactions
Shin CH, et al. (2022) Cytosolic microRNA-inducible nuclear translocation of Cas9 protein for disease-specific genome modification. Nucleic Acids Res 50(10):5919-5933. 2022CRISPR
Mohamed ISE, et al. (2022) Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo. Pharmaceutics 14:1173. 2022Cancer studiesGeneral
Onori ME, et al. (2022) Genetics and Sport Injuries: New Perspectives for Athletic Excellence in an Italian Court of Rugby Union Players. Genes 13(6):995. 2022Other
Jiang L, et al. (2022) Salidroside attenuates sepsis-associated acute lung injury through PPP1R15A mediated endoplasmic reticulum stress inhibition. Bioorg Med Chem June 1 doi: 10.1016/j.bmc.2022.116865. 2022Other
Chalise U, et al. (2022) MMP-12 polarizes the neutrophil signalome towards an apoptotic signature. J Proteomics Jun 1 doi: 10.1016/j.jprot.2022.104636. 2022Cell signaling
Siddoway AC, et al. (2022) Structural Stability and Antigenicity of Universal Equine H3N8 Hemagglutinin Trimer upon Release from Polyanhydride Nanoparticles and Pentablock Copolymer Hydrogels. ACS Biomater Sci Eng May 23 doi: 10.1021/acsbiomaterials.2c00219. 2022Other
Yang HY, et al. (2022) Glycogen synthase kinase‐3β inhibition decreases inflammation and relieves cancer induced bone pain via reducing Drp1‐mediated mitochondrial damage. J Cell Mol Med Jun 10 doi: 10.1111/jcmm.17432.2022Cancer studiesGeneral
Csizmarik A, et al. (2022) Proteome profiling of enzalutamide‐resistant cell lines and serum analysis identified ALCAM as marker of resistance in castration‐resistant prostate cancer. Int J Cancer Jun 11 doi: 10.1002/ijc.34159. 2022Cancer studiesGeneral
Hallacli E, et al. (2022) The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell 185(12):2035-2056.e33. 2022Neurobiology
Vasquez I, et al. (2022) Comparative Genomics of Typical and Atypical Aeromonas salmonicida Complete Genomes Revealed New Insights into Pathogenesis Evolution. Microorganisms 10(1):189. 2022Microorganisms and model organisms
Kim S, et al. (2022) Phosphorylation of GluA1-Ser831 by CaMKII activation in the caudate and putamen is required for behavioral sensitization after challenge nicotine in rats. Int J Neuropsychopharmacol Jun 9 doi: 10.1093/ijnp/pyac034.2022Neurobiology
Yang J, et al. (2022) Mmu_circ_0000271 regulated the growth of ox-LDL-stimulated mouse vascular smooth muscle cells via sponging miR-5123. Genes Genomics Jun 6 doi: 10.1007/s13258-022-01268-3. 2022Other
Peng Y, et al. (2022) The Drosophila hnRNP F/H homolog Glorund recruits dFMRP to inhibit nanos translation elongation. Nucleic Acids Res Jun 14 doi: 10.1093/nar/gkac500.2022Other
Chen N, et al. (2022) YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4. Cell Rep 39(11):110970. 2022Cancer studiesSquamous cell carcinoma
Guilloteau E, et al. (2022) Murine in utero exposure to simulated complex urban air pollution disturbs offspring gut maturation and microbiota during intestinal suckling-to-weaning transition in a sex-dependent manner. Part Fibre Toxicol 19(1):41.2022Other
Li W, et al. (2022) The downregulation of miR‐22 and miR‐372 may contribute to gestational diabetes mellitus through regulating glucose metabolism via the PI3K/AKT/GLUT4 pathway. J Clin Lab Anal Jun 17 doi: 10.1002/jcla.245572022Cell signaling
Liu D, et al. (2022) Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development. Mol Psychiatry Jun 14 doi: 10.1038/s41380-022-01654-z. 2022Neurobiology
Suthon S, et al. (2022) GATA4 and estrogen receptor alpha bind at SNPs rs9921222 and rs10794639 to regulate AXIN1 expression in osteoblasts Hum Genet Jun 9 doi: 10.1007/s00439-022-02463-8. 2022Disease studyBiomarker research
Giuliani E, et al. (2022) Obesity-induced follicular phase endometrial proteome dysregulation in a well-phenotyped population. F S Sci Jun 13 doi: 10.1016/j.xfss.2022.06.002. 2022Other
Lee BR, et al. (2022) Ascorbate peroxidase‐mediated in situ labelling of proteins in secreted exosomes. J Extracell Vesicles 11(6):e12239. 2022Method development
Singh N, et al. (2022) BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1. Sci Adv 8(24):eabo1286. 2022Other
Garcia-Gerique L, et al. (2022) MIF/CXCR4 signaling axis contributes to survival, invasion, and drug resistance of metastatic neuroblastoma cells in the bone marrow microenvironment. BMC Cancer 22(1):669. 2022Cancer studiesGeneral
Jiang N, et al. (2022) Inhibition of Cpt1a alleviates oxidative stress-induced chondrocyte senescence via regulating mitochondrial dysfunction and activating mitophagy. Mech Ageing Dev 205:111688.2022Cancer studiesGeneral
Haworth AS, et al. (2022) Subcellular dynamics and functional activity of the cleaved intracellular domain of the Na+ channel β1 subunit. J Biol Chem Jun 22 doi: 10.1016/j.jbc.2022.102174.2022Cancer studiesBreast cancer
Figueiredo J, et al. (2022) Encapsulation of the septal cell wall protects Streptococcus pneumoniae from its major peptidoglycan hydrolase and host defenses. PLoS Pathog 18(6):e1010516. 2022Microorganisms and model organisms
Yang YY, et al. (2022) Moderate Dose Irradiation Induces DNA Damage and Impairments of Barrier and Host Defense in Nasal Epithelial Cells in vitro. J Inflamm Res 2022(15):3661—3675. 2022DNA repair process
Othmène YB, et al. (2022) Triazole fungicide tebuconazole induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway. Environ Toxicol Pharmacol Jun 23 doi: 10.1016/j.etap.2022.103919. 2022Cell signaling
TJ Yang TJ, et al. (2022) Tumor suppressor BAP1 nuclear import is governed by transportin-1. J Cell Biol 221(6):e202201094. 2022Cancer studiesGeneral
Sahu BP, et al. (2022) Genome-wide identification and characterization of microsatellite markers within the Avipoxviruses. 3 Biotech 12(5):113. 2022Disease studyBiomarker research
West PK, et al. (2022) The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes. J Neuroinflammation 19(1):96. 2022Neurobiology
M Diefenbacher M, et al. (2022) Interactions between Influenza A Virus Nucleoprotein and Gene Segment Untranslated Regions Facilitate Selective Modulation of Viral Gene Expression. J Virol Apr 25 doi: 10.1128/jvi.00205-22. 2022Microorganisms and model organisms
Xu WF, et al. (2022) Octreotide-based therapies effectively protect mice from acute and chronic gastritis. Eur J Pharmacol Apr 26 doi: 10.1016/j.ejphar.2022.174976. 2022Drug mechanism
Menna M, et al. (2022) Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models. Eur J Med Chem 237:114410. 2022Cancer studiesGeneral
Liu Y, et al. (2022) Whole-Exome Sequencing of Germline Variants in Non-BRCA Families with Hereditary Breast Cancer. Biomedicines 10(5):1004.2022Cancer studiesBreast cancer
Esfahani SA, et al. (2022) Hyperpolarized [1-13C] Pyruvate Magnetic Resonance Spectroscopic Imaging for Evaluation of Early Response to Tyrosine Kinase Inhibition Therapy in Gastric Cancer. Mol Imaging Biol Apr 25 doi: 10.1007/s11307-022-01727-z. 2022Cancer studiesGastric cancer
Thompson L, et al. (2022) An eIF3d-dependent switch regulates HCMV replication by remodeling the infected cell translation landscape to mimic chronic ER stress. Cell Rep 39(5):110767. 2022Other
Xue JB, et al. (2022) Heart failure in mice induces a dysfunction of the sinus node associated with reduced CaMKII signaling. J Gen Physiol 154(9):e202112895. 2022Cell signaling
Yang X, et al. (2022) MARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation. Sci Signal 15(732):eabk3067. 2022Other
Butta GM, et al. (2022) Heterogeneity of Latency Establishment in the Different Human CD4+ T Cell Subsets Stimulated with IL-15. J Virol May 2 doi: 10.1128/jvi.00379-22. 2022Microorganisms and model organisms
Siddiqui SH, et al. (2022) Modulatory effects of cell–cell interactions between porcine skeletal muscle satellite cells and fibroblasts on the expression of myogenesis-related genes. Journal of Applied Animal Research  50(1):259-268. 2022Other
Yin W, Qian S. (2022) Delivery of cisplatin and resiquimod in nanomicelles for the chemoimmunotherapy of ovarian cancer. Cancer Nano 13:82022Cancer studiesOvarian cancer
Qiao J, et al. (2022) Neuroprotective effect of Ginsenoside Re against neurotoxin‑induced Parkinson's disease models via induction of Nrf2. Mol Med Rep 25(6):215. 2022Neurobiology
Dong C, et al. (2022) A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells. Nat Commun 13(1):2548. 2022CRISPR
Mahari S, et al. (2022) Probe-Free Nanosensor for the Detection of Salmonella Using Gold Nanorods as an Electroactive Modulator. Food Chem 390:133219. 2022Method development
Mohammed HHH, et al. (2022) New 1, 2, 3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization. J Enzyme Inhib Med Chem 37(1):1346-1363.2022Cancer studiesGeneral
Kshirsagar PG, et al. (2022) DNA-gold nanoprobe-based integrated biosensing technology for non-invasive liquid biopsy of serum miRNA: A new frontier in prostate cancer diagnosis. Nanomedicine May 12 doi: 10.1016/j.nano.2022.102566.  2022Cancer studiesGeneral
Harbuzariu A, et al. (2022) Neuregulin-1/ErbB4 signaling modulate Plasmodium falciparum HRP2-induced damage to brain cortical organoids. ISCIENCE May 14 doi: https://doi.org/10.1016/j.isci.2022.104407.2022Neurobiology
Jain RG, et al. (2022) Foliar application of clay-delivered RNA interference for whitefly control. Nat Plants 8(5):535-548. 2022Plant sciences
Taniguchi H, et al. (2022) WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC. Cell Rep 39(7):110814. 2022Cancer studiesLung cancer
Lu Y, et al. (2022) Patchouli alcohol protects against myocardial ischaemia–reperfusion injury by regulating the Notch1/Hes1 pathway. Pharm Biol 60(1):949-957. 2022Cell signaling
Shahdeo D, et al. (2022) Label free detection of SARS CoV-2 Receptor Binding Domain (RBD) protein by fabrication of gold nanorods deposited on electrochemical immunosensor (GDEI). Biosens Bioelectron 212:114406. 2022Method development
Rouault AAJ, et al. (2022) MRAP2 inhibits β-arrestin recruitment to the ghrelin receptor by preventing GHSR1a phosphorylation. J Biol Chem May 20 doi: 10.1016/j.jbc.2022.102057. 2022Cell signaling
Parashar D, et al. (2022) Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance. Cancers (Basel) 14(4):958.2022Cancer studiesOvarian cancer
Ni C, et al. (2022) Labeling of heterochronic ribosomes reveals C1ORF109 and SPATA5 control a late step in human ribosome assembly. Cell Rep 38(13):110597. 2022Other
Niemeyer CS, et al. (2022) VZV Infection of Primary Human Adrenal Cortical Cells Produces a Proinflammatory Environment without Cell Death. Viruses 14(4):674. 2022Other
Leo IR, et al. (2022) Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines. Nat Commun 13(1):1691. 2022Cancer studiesBlood cancer
Donko A, et al. (2022) Interpretation of Dihydrorhodamine-1, 2, 3 Flow Cytometry in Chronic Granulomatous Disease: an Atypical Exemplar. J Clin Immunol Mar 28 doi: 10.1007/s10875-022-01217-5.2022Other
Jamieson F, et al. (2022) Ethylene signaling modulates Arabidopsis thaliana nitrate metabolism. Planta 255(5):94. 2022Plant sciences
Lee HK, et al. (2022) Sinkihwan-gamibang ameliorates puromycin aminonucleoside-induced nephrotic syndrome. Chin J Nat Med 20(3):177-184. 2022Other
Gomes C, et al. (2022) Neurotoxic Astrocytes Directly Converted from Sporadic and Familial ALS Patient Fibroblasts Reveal Signature Diversities and miR-146a Theragnostic Potential in Specific Subtypes. Cells 11(7):1186. 2022Neurobiology
Suzuki Y, et al. (2022) Rhodococcus equi U19 strain harbors a nonmobilizable virulence plasmid. Microbiol Immunol Mar 11 doi: 10.1111/1348-0421.12975. 2022Microorganisms and model organisms
Cilibrasi V, et al. (2022) Synthesis of 2H-Imidazo [2′, 1': 2, 3][,] thiazolo [4, 5-e] isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations2022Cancer studiesGeneral
Ghaleb Y, et al. (2022) Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia. Metabolites 12(3):262. 2022Disease studyBiomarker research
Sun H, et al. (2022) TRIB2 regulates the expression of miR 33a 5p through the ERK/c Fos pathway to affect the imatinib resistance of chronic myeloid leukemia cells. Int J Oncol 60(5):49. 2022Cancer studiesBlood cancer
Wang YH, et al. (2022) Golgin Imh1 and GARP complex cooperate to restore the impaired SNARE recycling transport induced by ER stress. Cell Rep 38(12):110488. 2022Other
Park H, et al. (2022) miR-200c suppression increases tau hyperphosphorylation by targeting 14-3-3γ in early stage of 5xFAD mouse model of Alzheimer's disease. Int J Biol Sci 18(5):2220-2234. 2022Neurobiology
Mallard J, et al. (2022) Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients. J Cachexia Sarcopenia Muscle Apr 4 doi: 10.1002/jcsm.129912022Cancer studiesBreast cancer
Boltz F, et al. (2022) Nimodipine Exerts Beneficial Effects on the Rat Oligodendrocyte Cell Line OLN-93. Brain Sci 12(4):476. 2022Neurobiology
Zorzan E, et al. (2022) Hypermethylation-Mediated Silencing of CIDEA, MAL and PCDH17 Tumour Suppressor Genes in Canine DLBCL: From Multi-Omics Analyses to Mechanistic Studies. Int J Mol Sci 23(7):4021.2022Cancer studiesGeneral
Park SK, et al. (2022) Peanut (Arachis hypogaea) sprout prevents high-fat diet-induced cognitive impairment by improving mitochondrial function. Sci Rep 12(1):6213. 2022Neurobiology
Zhang K, et al. (2022) Sevoflurane attenuates hepatic ischemia reperfusion injury by the miR-122/Nrf2 pathway. Ann Transl Med 10(6):350. 2022Other
Ponterio G, et al. (2022) Alpha-Synuclein is Involved in DYT1 Dystonia Striatal Synaptic Dysfunction. Mov Disord Apr 14 doi: 10.1002/mds.29024. 2022Neurobiology
Yang HD, et al. (2022) Effect of Neiyi Prescription of QIU on autophagy and angiogenic ability of endometriosis via the PPARγ/NF-κB signaling pathway. Arch Gynecol Obstet Apr 3 doi: 10.1007/s00404-022-06537-w. 2022Cell signaling
Barros-Álvarez X, et al. (2022) The tethered peptide activation mechanism of adhesion GPCRs. Nature Apr 13 doi: 10.1038/s41586-022-04575-7. 2022Structural biology/Protein interactions
Tang B, et al. (2022) xCT contributes to colorectal cancer tumorigenesis through upregulation of the MELK oncogene and activation of the AKT/mTOR cascade. Cell Death Dis 13(4):373. 2022Cancer studiesColorectal cancer
Debnath S, et al. (2022) Eriodictyol mediated selective targeting of the TNFR1/FADD/TRADD axis in cancer cells induce apoptosis and inhibit tumor progression and metastasis. Transl Oncol 21:101433. 2022Cancer studiesGeneral
Tabler CO, et al. (2022) The HIV-1 Viral Protease Is Activated during Assembly and Budding Prior to Particle Release. J Virol Apr 19 doi: 10.1128/jvi.02198-21. 2022Microorganisms and model organisms
Katsumura S, et al. (2022) Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure. Cell Metab 34(4):564-580.e8. 2022Other
Andhare DS, et al. (2022) Protein-protein interactions on membrane surfaces analysed using pull-downs with supported bilayers on silica beads. J Membr Biol Feb 28 doi: 10.1007/s00232-022-00222-4.2022Method development
Uthailak N, et al. (2022) Production of recombinant β-glucocerebrosidase in wild-type and glycoengineered transgenic Nicotiana benthamiana root cultures with different N-glycan profiles. J Biosci Bioeng Feb 18 doi: 10.1016/j.jbiosc.2022.01.002. 2022Plant sciences
Parashar D, et al. (2022) Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance. Cancers (Basel) 14(4):958. 2022Cancer studiesGeneral
Park JS, et al. (2022) Proteomic changes in broiler liver by body weight differences under chronic heat stress. Poultry Science Feb 23 doi: 10.1016/j.psj.2022.101794. 2022Other
Bakrania BA, et al. (2022) Sustained Elevated Circulating Activin A Impairs Global Longitudinal Strain in Pregnant Rats: A Potential Mechanism for Preeclampsia-Related Cardiac Dysfunction. Cells 11(4):742. 2022Other
Singh V, et al. (2022) Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice. Sci Rep 12(1):29412022Cell Signaling
Kiss E, et al. (2022) Methyl Donors Reduce Cell Proliferation by Diminishing Erk-Signaling and NFkB Levels, While Increasing E-Cadherin Expression in Panc-1 Cell Line2022Cancer studiesPancreatic cancer
Budayeva HG, et al. (2022) Phosphoproteome Profiling of the Receptor Tyrosine Kinase MuSK Identifies Tyrosine Phosphorylation of Rab GTPases. Mol Cell Proteomics Feb 25 doi: 10.1016/j.mcpro.2022.100221. 2022Cell Signaling
Hoang ATN, et al. (2022) Casein kinase I inhibitor D4476 influences autophagy and apoptosis in chloroquine-induced adult retinal pigment epithelial-19 cells. Exp Eye Res 218:109004. 2022Cell Signaling
Dong Q, et al. (2022) Sensitive and selective detection of Mucin1 in pancreatic cancer using hybridization chain reaction with the assistance of Fe3O4@ polydopamine nanocomposites. J Nanobiotechnology 20(1):94. 2022Cancer studiesPancreatic cancer
Moon SY, et al. (2022) Fraxinol Stimulates Melanogenesis in B16F10 Mouse Melanoma Cells through CREB/MITF Signaling. Molecules 27(5):1549.2022Cancer studiesSkin cancer
Cui Z, et al. (2022) miR-103a-3p Silencing Ameliorates Calcium Oxalate Deposition in Rat Kidney by Activating the UMOD/TRPV5 Axis. Dis Markers 2022:2602717. 2022Other
Ma X, et al. (2022) Dimeric G-Quadruplex: An Efficient Probe for Ultrasensitive Fluorescence Detection of Mustard Compounds. Anal Chem 94(9):4112-4118. 2022Method development
Shahi I, et al. (2022) Genome-Wide CRISPR-Cas9 Screen Does Not Identify Host Factors Modulating Streptococcus agalactiae β-Hemolysin/Cytolysin-Induced Cell Death. Microbiol Spectr 10(1):e0218621. 2022CRISPR
Tolomeo AM, et al. (2022) Temperature-Related Effects of Myocardial Protection Strategies in Swine Hearts after Prolonged Warm Ischemia. Antioxidants 11(3):476. 2022Other
Yang W, et al. (2022) Immune-responsive gene 1 protects against liver injury caused by concanavalin A via the activation Nrf2/HO-1 pathway and inhibition of ROS activation pathways. Free Radic Biol Med 182:108-118. 2022Cell Signaling
Vougioukalaki M, et al. (2022) Cell adhesion tunes inflammatory TPL2 kinase signal transduction. Cell Mol Life Sci 79(3):156.2022Cell Signaling
Wang H, et al. (2022) Bisphosphonate of Zoledronate Has Antiapoptotic Effect on Hypoxia/Reoxygenation Injury in Human Embryonic Stem Cell-Derived Cardiomyocytes Through Trk Signaling Pathway. Cell Biochem Biophys doi: 10.1007/s12013-021-01031-7. 2022Cell Signaling
Lee J, et al. (2022) Improved stability of vitamin D3 encapsulated in whey protein isolate microgels. Int Dairy J 129: 105351.2022Other
Song ES, et al. (2022) Novel Corneal Endothelial Cell Carrier Couples a Biodegradable Polymer and a Mesenchymal Stem Cell-Derived Extracellular Matrix. ACS Appl Mater Interfaces 14(10):12116-12129.2022Stem cells
Rotoli BM, et al. (2022) Desmopressin Stimulates Nitric Oxide Production in Human Lung Microvascular Endothelial Cells. Biomolecules 12(3): 389. 2022Other
Cui X, et al. (2022) A clinical study on the effects of dexmedetomidine and propofol on erythrocyte deformability during anaesthesia. Pak J Pharm Sci 29(5):1615-1618.2022Other
Nguyen XP, et al. (2022) Expression of FMRpolyG in Peripheral Blood Mononuclear Cells of Women with Fragile X Mental Retardation 1 Gene Premutation. Genes 13(3): 451.2022Other
Hou W, et al. (2022) Integrin subunit beta 8 contributes to lenvatinib resistance in HCC. Hepatol Commun Mar 3 doi: 10.1002/hep4.1928.2022Cancer studiesLiver cancer
Ren J, et al. (2022) Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liver. Cell Biosci 12(1):26. 2022CRISPR
Barilli A, et al. (2022) Immune-Mediated Inflammatory Responses of Alveolar Epithelial Cells: Implications for COVID-19 Lung Pathology. Biomedicines 10(3): 618. 2022Cell Signaling
Pinel K, et al. (2022) Are the Main Methionine Sources Equivalent? A Focus on DL-Methionine and DL-Methionine Hydroxy Analog Reveals Differences on Rainbow Trout Hepatic Cell Line Functions. Int. J. Mol. Sci. 23(6): 2935. 2022Other
Kim EH, et al. (2022) PDL1-binding peptide/anti-miRNA21 conjugate as a therapeutic modality for PD-L1high tumors and TAMs. J Control Release 345:62-74. 2022Cancer studiesSkin cancer
Daruich A, et al. (2022) Comparative Analysis of Urso-and Tauroursodeoxycholic Acid Neuroprotective Effects on Retinal Degeneration Models. Pharmaceuticals 15(3): 334.2022Neurobiology
Teng JW, et al. (2022) Icariin triggers osteogenic differentiation of bone marrow stem cells by up-regulating miR-335–5p. Exp Cell Res 414(2):113085.2022Stem cells
Zhang X, et al. (2022) MiR-874-3p represses the migration and invasion yet promotes the apoptosis and cisplatin sensitivity via being sponged by long intergenic non-coding RNA 00922 and targeting Glycerophosphodiester Phosphodiesterase Domain Containing 5 (GDPD5) in gastric cancer cells. Bioengineered 13(3):7082-71042022Cancer studiesGastric cancer
Lee S, et al. (2022) Quantitative analysis of PACAP-38 and amyloid beta composition using a dual reaction in reduced graphene oxide biosensor to verify the neuroprotective role of PACAP-38. Sens Actuators B Chem 361: 131727. 2022Neurobiology
S Olivera-Bravo S, et al. (2022) Neuroprotective effects of violacein in a model of inherited amyotrophic lateral sclerosis. Sci Rep 12(1):4439. 2022Neurobiology
Verkest C, et al. (2022) Intrinsically disordered intracellular domains control key features of the mechanically-gated ion channel PIEZO2. Nat Commun 13(1):1365.2022Structural biology/Protein interactions
Ratti S, et al. (2022) Impact of phospholipase C β1 in glioblastoma: a study on the main mechanisms of tumor aggressiveness. Cell Mol Life Sci 79(4):195. 2022Cancer studiesBrain cancer
Südfeld C, et al. (2022) Accumulation of medium chain fatty acids in Nannochloropsis oceanica by heterologous expression of Cuphea palustris thioesterase FatB1. Algal Res 64: 102665. 2022Microorganisms and model organisms
Kim K, et al. (2022) Hispidulin Ameliorates Endotoxin-Induced Acute Kidney Injury in Mice. Molecules 27(6): 2019.2022Other
Prvulovic M, et al. (2022) Calorie restriction changes the anxiety-like behaviour of ageing male Wistar rats in an onset-and duration-dependent manner. Mech Ageing Dev Mar 21 doi: 10.1016/j.mad.2022.111666. 2022Other
Tanuma S, et al. (2022) A Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling. Int J Mol Sci 23(7): 3426. 2022Cancer studiesColon cancer
Milosevic K, et al. (2022) Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response. Int J Mol Sci 23(7): 3561. 2022Neurobiology
Chen J, et al. (2022) Polyphenols in Ilex latifolia Thunb. inhibit human lung cancer cell line A549 by regulation of the PI3K-Akt signaling pathway. BMC Complement Med Ther 22(1):85. 2022Cancer studiesLung cancer
Clark KL, et al. (2022) Perfluorooctanoic acid promotes proliferation of the human granulosa cell line HGrC1 and alters expression of cell cycle genes and Hippo pathway effector YAP1. Reprod Toxicol Mar 25 doi: 10.1016/j.reprotox.2022.03.011. 2022Cell Signaling
Arakawa M, et al. (2022) Flavivirus recruits the valosin-containing protein (VCP)/NPL4 complex to induce stress granule disassembly for efficient viral genome replication. J Biol Chem Jan 18 doi: 10.1016/j.jbc.2022.101597. 2022Structural biology/Protein interactions
Jang DG, et al. (2022) Integrin β-like 1 protein (ITGBL1) promotes cell migration by preferentially inhibiting integrin-ECM binding at the trailing edge. Genes Genomics Jan 23 doi: 10.1007/s13258-021-01204-x. 2022Other
Korobeynikov VA and Lyashchenko AK/ (2022) Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis. Nat Med 28(1):104-116. 2022Neurobiology
Zigrossi A , et al. (2022) SELENOF is a new tumor suppressor in breast cancer. Oncogene Jan 27 doi: 10.1038/s41388-021-02158-w.2022Cancer studiesBreast cancer
Yang HH, et al. (2022) Anti-Excitotoxic Effects of N-Butylidenephthalide Revealed by Chemically Insulted Purkinje Progenitor Cells Derived from SCA3 iPSCs. Int. J. Mol. Sci 23(3):1391. 2022Stem cells
Wang L, et al. (2022) FOXM1-induced TYMS upregulation promotes the progression of hepatocellular carcinoma. Cancer Cell Int 22(1):47.2022Cancer studiesLiver cancer
Nagaoka M, et al. (2022) Targeted Delivery of Immunostimulatory CpG Oligodeoxynucleotides to Antigen-Presenting Cells in Draining Lymph Nodes by Stearic Acid Modification and and Nanostructurization. Int. J. Mol. Sci. 23(3): 1350. 2022Structural biology/Protein interactions
Melnikova AME, et al. (2022) The p. Glu787Lys variant in the GRIA3 gene causes developmental and epileptic encephalopathy mimicking structural epilepsy in a female patient. Eur J Med Genet 65(3):1044422022Neurobiology
Li Y, et al. (2022) Cerebrospinal Fluid Extracellular Vesicles with Distinct Properties in Autoimmune Encephalitis and Herpes Simplex Encephalitis. Mol Neurobiol Jan 27 doi: 10.1007/s12035-021-02705-2. 2022Neurobiology
Skertich NJ, et al. (2022) Expression of Immunomodulatory Checkpoint Molecules in Drug-Resistant Neuroblastoma: An Exploratory Study. Cancers 14(3):751. 2022Cancer studiesGeneral
Jia X, et al. (2022) Facile one-step synthesis of NIR-Responsive siRNA-Inorganic hybrid nanoplatform for imaging-guided photothermal and gene synergistic therapy. Biomaterials 282:121404. 2022Method development
Sia KC, et al. (2022) First use of gene therapy to treat growth hormone resistant dwarfism in a mouse model. Gene Ther Feb 1 doi: 10.1038/s41434-022-00313-w. 2022Method development
Lee HK, et al. (2022) Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys. Sci Rep 12(1):1646. 2022Disease studyBiomarker research
Cheng L, et al. (2022) Long noncoding RNA RP11-241J12. 3 targeting pyruvate carboxylase promotes hepatocellular carcinoma aggressiveness by disrupting pyruvate metabolism and the DNA mismatch repair system. Mol Biomed 3(1):4. 2022Cancer studiesLiver cancer
Sun Y, et al. (2022) Pharmacologic induction of PGC‐1α stimulates fetal haemoglobin gene expression. Br J Haematol Feb 4 doi: 10.1111/bjh.18042. 2022Other
Pakarinen E, et al. (2022) CDNF and MANF regulate ER stress in a tissue-specific manner. Cell Mol Life Sci 79(2):124. 2022Cell signaling
Kang D, et al. (2022) Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis. Nat Commun 13(1):779. 2022Other
Watanabe H, et al. (2022) Transcription factor Hhex negatively regulates osteoclast differentiation by controlling cyclin‐dependent kinase inhibitors. JBMR Plus Jan 28 doi: 10.1002/jbm4.10608. 2022Cell signaling
Ljungblad L, et al. (2022) Omega-3 fatty acids decrease CRYAB, production of oncogenic prostaglandin E2 and suppress tumor growth in medulloblastoma. Life Sci 295:120394. 2022Cancer studiesBrain cancer
Omura CM, et al. (2022) Decrease of IL-1β and TNF in the Spinal Cord Mediates Analgesia Produced by Ankle Joint Mobilization in Complete Freund Adjuvant-Induced Inflammation Mice Model. Front Physiol 12:816624. 2022Other
Xu Z, et al. (2022) Cabazitaxel suppresses the proliferation and promotes the apoptosis and radiosensitivity of castration-resistant prostate cancer cells by inhibiting PI3K/AKT pathway. Am J Transl Res 14(1):166-181. 2022Cancer studiesGeneral
Salamone IM, et al. (2022) Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms. J Clin Invest Feb 10 doi: 10.1172/JCI149828. 2022Other
Manna VJ, et al. (2022) The dynamic nature of the Coronavirus receptor, angiotensin-converting enzyme 2 (ACE2) in differentiating airway epithelia. BBA Adv 2:100044. 2022Microorganisms and model organisms
Li Y, et al. (2022) LncRNA LINC01315 silencing modulates cancer stem cell properties and epithelial-to-mesenchymal transition in colorectal cancer via miR-484/DLK1 axis. Cell Cycle Feb 13 doi: 10.1080/15384101.2022.2033415. 2022Cancer studiesColorectal cancer
Czajka TF, et al. (2022) Single-Domain Antibodies for Intracellular Toxin Neutralization. Methods Mol Biol 2446:469-487. 2022Method development
Casas-Sanchez A, et al. (2022) Inhibition of Protein N-Glycosylation Blocks SARS-CoV-2 Infection. mBio 13(1):e0371821. 2022Microorganisms and model organisms
Mandi CS, et al. (2022) Cleavage of Abasic Sites in DNA by an Aminoquinoxaline Compound: Augmented Cytotoxicity and DNA Damage in Combination with an Anticancer Drug Chlorambucil in Human Colorectal Carcinoma Cells. ACS Omega Feb 18 doi: 10.1021/acsomega.1c04962. 2022Cancer studiesColorectal cancer
Rudy MJ, et al. (2022) Density Analysis of Enterovirus D68 Shows Viral Particles Can Associate with Exosomes. Microbiol Spectr 10(1):e0245221. 2022Microorganisms and model organisms
Liu M, et al. (2022) miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1. Cardiol Res Pract Feb 17 doi: 10.1155/2022/7687154 2022Other
Ahn SH, et al. (2022) Rhynchosia volubilis Promotes Cell Survival via cAMP-PKA/ERK-CREB Pathway. Pharmaceuticals (Basel) 15(1):73. 2022 Cell signaling
Choi YH , et al. (2022) Antiandrogenic activity of Riboflavin 5′-phosphate (FMN) in 22Rv1 and LNCaP human prostate cancer cell lines. Eur J Pharmacol Jan 5 doi: 10.1016/j.ejphar.2022.174743. 2022 Cancer studies General
Furuyama W, et al. (2022) Rapid Protection from COVID-19 in Nonhuman Primates Vaccinated Intramuscularly but Not Intranasally with a Single Dose of a Vesicular Stomatitis Virus-Based Vaccine. mBio Jan 11 doi: 10.1128/mbio.03379-21. 2022 Other
Harlaar N, et al. (2022) Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation. Nat Biomed Eng Jan 6 doi: 10.1038/s41551-021-00827-5. 2022 Other
Kono M, et al. (2022) Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma. Oncoimmunology 11(1):2021619. 2022 Cancer studies Squamous cell carcinoma
Lee H, et al. (2022) Soybean-Derived Peptides Attenuate Hyperlipidemia by Regulating Trans-Intestinal Cholesterol Excretion and Bile Acid Synthesis. Nutrients 14(1):95. 2022 Plant sciences
Morgan SM, et la. (2022) The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity. Nat Commun 13(1):187. 2022 Structural biology/protein interactions
Starikova AV, et al. (2022) Therapeutic potential of highly functional codon-optimized microutrophin for muscle-specific expression. Sci Rep 12(1):848. 2022 Mitochondrial studies
Weixler D, et al. (2022) Recombinant production of the lantibiotic nisin using Corynebacterium glutamicum in a two-step process. Microb Cell Fact 21(1):11. 2022 Microorganisms and model organisms
Yin J, et al. (2022) Development of a whole-cell biosensor for detection of antibiotics targeting bacterial cell envelope in Bacillus subtilis. Appl Microbiol Biotechnol 106(2):789-798. 2022 Microorganisms and model organisms
Zhong J, et al. (2022) KCNIP3 silence promotes proliferation and epithelial-mesenchymal transition of papillary thyroid carcinoma through activating Wnt/β-catenin pathway. Tissue and Cell 75:101739. 2022 Cancer studies General
Acar NV, et al. (2021) An investigation of different intracellular parameters for Inborn Errors of Metabolism: Cellular stress, antioxidant response and autophagy. Free Radic Biol Med 179:190-199. 2021 Other
Adhikari A, et al, (2021) Myogenin is required for assembly of the transcription machinery on muscle genes during skeletal muscle differentiation. PLoS One 16(1):e0245618. 2021 Other
Ali A, et al. (2021) Inhibition of HDACs Suppresses Cell Proliferation and Cell Migration of Gastric Cancer by Regulating E2F5 Targeting BCL2. Life (Basel) 11(12):1425. 2021 Cancer studies Gastric cancer
Almeida-Toledano L, et al. (2021) Epigallocatechin Gallate Ameliorates the Effects of Prenatal Alcohol Exposure in a Fetal Alcohol Spectrum Disorder-Like Mouse Model. Int J Mol Sci 22(2):715. 2021 Other
Altman T, et al. (2021) Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins. Nat Commun 12(1):6914. 2021 Neurobiology
An X, et al. (2021) Discovery of a widespread presence bunyavirus that may have symbiont‐like relationships with different species of aphids. Insect Sci Dec 7 doi: 10.1111/1744-7917.12989. 2021 Microorganisms and model organisms
Arunkumar R, et al. (2021) Lutein and zeaxanthin reduce A2E and iso-A2E levels and improve visual performance in Abca4−/−/bco2−/− double knockout mice. Exp Eye Res 209:108680. 2021 Neurobiology
Avila H, et al. (2021) Intracellular Dynamin Elastin-like Polypeptides Assemble into Rodlike, Spherical, and Reticular Dynasomes. Biomacromolecules Dec 16 doi: 10.1021/acs.biomac.1c01251. 2021 Structural biology/protein interactions
Bade AN, et al. (2021) Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment. Mol Neurobiol Aug 14 doi: 10.1007/s12035-021-02508-5. 2021 Neurobiology
Bae IY, et al. (2021) TIMP‐1‐expressing breast tumor spheroids for the evaluation of drug penetration and efficacy. Bioeng Transl Med Dec 23 doi: 10.1002/btm2.10286. 2021 Cancer studies Breast cancer
Baker l, et al. (2021) Fidgetin-like 2 negatively regulates axonal growth and can be targeted to promote functional nerve regeneration. JCI Insight Apr 19 doi: 10.1172/jci.insight.138484. 2021 Neurobiology
Barilli A, et al. (2021) Organic cation transporters (OCTs/OCTNs) in human primary alveolar epithelial cells. Biochem Biophys Res Commun 576:27-32. 2021 Other
Barua R, et al. (2021) Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers. Molecules 26(4):882. 2021 Cancer studies Pancreatic cancer
Beveridge DJ, et al. (2021) The tumor suppressor miR-642a-5p targets Wilms Tumor 1 gene and cell-cycle progression in prostate cancer. Sci Rep 11(1):18003. 2021 Cancer studies General
Bian S, et al. (2021) Knockdown of p62/sequestosome enhances ginsenoside Rh2-induced apoptosis in cervical cancer HeLa cells with no effect on autophagy. Biosci Biotechnol Biochem, Feb 5 doi:10.1093/bbb/zbab019. 2021 Cell signaling
Burgess HM, et al. (2021) Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication. Genes Dev 35(13-14):1005-1019. 2021 Microorganisms and model organisms
Burr SD, et al. (2021) Rap1a Regulates Cardiac Fibroblast Contraction of 3D Diabetic Collagen Matrices by Increased Activation of the AGE/RAGE Cascade. Cells 10(6) 1286 2021 Cell signaling
Cai S, et al. (2021) Integrative analysis and experiments to explore angiogenesis regulators correlated with poor prognosis, immune infiltration and cancer progression in lung adenocarcinoma. J Transl Med 19(1):361. 2021 Cancer studies Lung cancer
Carano F, et al. (2021) Assessment of the structural and functional characteristics of human mesenchymal stem cells associated with a prolonged exposure of morphine. Sci Rep 11(1):19248. 2021 Stem cells
Carinci M, et al. (2021) TFG binds LC3C to regulate ULK1 localization and autophagosome formation. EMBO J May 1 doi: 10.15252/embj.2019103563 2021 Cell signaling
Carminita E, et al. (2021) DNAse-dependent, NET-independent pathway of thrombus formation in vivo. Proc Natl Acad Sci USA 118(28):e2100561118. 2021 Other
Chalise U, et al. (2021) S100A9 is a functional effector of infarct wall thinning after myocardial infarction. Am J Physiol Heart Circ Physiol Dec 10 doi: 10.1152/ajpheart.00475.2021. 2021 Other
Chang H, et al. (2021) PARP1 Is Targeted by miR-519a-3p and Promotes the Migration, Invasion, and Tube Formation of Ovarian Cancer Cells. Cancer Biother Radiopharm May 18 doi: 10.1089/cbr.2020.4394 2021 Cancer studies Ovarian cancer
Chen F, et al. (2021) Prognostic plasma exosomal microRNA biomarkers in patients with substance use disorders presenting comorbid with anxiety and depression. Sci Rep 11(1):6271. 2021 Disease study: biomarker research
Chen L, et al. (2021) Downregulation of GTSE1 leads to the inhibition of proliferation, migration, and Warburg effect in cervical cancer by blocking LHDA expression. J Obstet Gynaecol Res Sep 5 doi: 10.1111/jog.15000. 2021 Cancer studies General
Chen M, et al. (2021) Downregulation of triggering receptor expressed on myeloid cells 1 inhibits invasion and migration of liver cancer cells by mediating macrophage polarization. Oncol Rep 45(4):1-12. 2021 Cancer studies Liver cancer
Cheng TY, et al. (2021) β-(1→ 4) Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex. Cells Jul 5 doi: 10.3390/cells10071774. 2021 Neurobiology
Cherngwelling R, et al. (2021) Agomelatine protects against obesity-induced renal injury by inhibiting endoplasmic reticulum stress/apoptosis pathway in rats. Toxicol Appl Pharmacol 425:115601. 2021 Cell signaling
Chompunud Na Ayudhya C, et al. (2021) MRGPRX2 Activation by Rocuronium: Insights from Studies with Human Skin Mast Cells and Missense Variants. Cells 10(1):156. 2021 Other
Civera-Tregón A, et al. (2021) Mitochondria and calcium defects correlate with axonal dysfunction in GDAP1-related Charcot-Marie-Tooth mouse model. Neurobiol Dis Feb 11 doi: 10.1016/j.nbd.2021.105300. 2021 Neurobiology
Contreras L, et al. (2021) Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms. Pharmacol Rep Aug 26 doi: 10.1007/s43440-021-00322-3. 2021 Cancer studies General
D'Acunzo, P, et al, (2021) Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome. Sci Adv 7(7):eabe5085. 2021 Neurobiology
Dai C, et al. (2021) A non‐translational role of threonyl‐tRNA synthetase in regulating JNK signaling during myogenic differentiation. FASEB J 35(10):e21948. 2021 Cell signaling
Danac JMC, et al. (2021) CircPVT1 attenuates negative regulation of NRAS by let-7 and drives cancer cells towards oncogenicity. Sci Rep 11(1):9021 2021 Cancer studies Other
Daruich A, et al. (2021) Oral Ursodeoxycholic Acid Crosses the Blood Retinal Barrier in Patients with Retinal Detachment and Protects Against Retinal Degeneration in an Ex Vivo Model. Neurotherapeutics Feb 3 doi: 10.1007/s13311-021-01009-6. 2021 Drug mechanism
Das P, et al. (2021) Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression. J Biol Chem Sep 14 doi: 10.1016/j.jbc.2021.101198. 2021 Microorganisms and model organisms
Delgado-Peraza F, et al. (2021) Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease. Cells 10(5):993 2021 Neurobiology
Demonbreun AR, et al. (2021) Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy. Sci Transl Med 13(610):eabf0376. 2021 Drug mechanism
Di Filippo M, et al. (2021) Interleukin-17 affects synaptic plasticity and cognition in an experimental model of multiple sclerosis. Cell Rep 37(10):110094. 2021 Neurobiology
Diller T, et al. (2021) Biological Validation of a Novel Process and Product for Quantitating Western Blots. J Biotechnol 326: 52–60. 2021 Method development
Dong P, et al. (2021) Runjing Decoction alleviated cyclophosphamide‐induced oligoasthenospermia rats by inhibiting cell apoptosis via RXFP1/AKT/FOXO1 pathway. Andrologia Aug 16 doi: 10.1111/and.14216 2021 Cell signaling
Douglass M, et al. (2021) EXPRESS: L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells. Pulm Circ Mar 16 doi: 10.1177/20458940211006289. 2021 Other
Dupont L, et al. (2021) The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr. Cell Host Microbe S1931-3128(21)00101-3. 2021 Other
Ebelt ND, et al. (2021) Collagenase-Expressing Salmonella Targets Major Collagens in Pancreatic Cancer and Improves Immune Checkpoint Blockade. Cancers (Basel) 13(14): 3565. 2021 Cancer studies Pancreatic cancer
F Zhang F, et al. (2021) Crocin ameliorates atherosclerosis by promoting the reverse cholesterol transport and inhibiting the foam cell formation via regulating PPARγ/LXR-α. Cell Cycle Jan 3 doi: 10.1080/15384101.2021.2015669. 2021 Other
Fasolato L, et al. (2021) An Iron Shield to Protect Epigallocatehin-3-Gallate from Degradation: Multifunctional Self-Assembled Iron Oxide Nanocarrier Enhances Protein Kinase CK2 Intracellular Targeting and Inhibition. Pharmaceutics 13(8):1266. 2021 Structural biology and protein interaction
Frazier TW, et al. (2021) Cross-level analysis of molecular and neurobehavioral function in a prospective series of patients with germline heterozygous PTEN mutations with and without autism. Mol Autism 12(1):5. 2021 Disease study: Biomarker research
Freeman AJ, et al. (2021) HOIP limits anti‐tumor immunity by protecting against combined TNF and IFN‐gamma‐induced apoptosis. EMBO Rep Sep 1 doi: 10.15252/embr.202153391. 2021 Cancer studies Skin cancer
Fu T, et al. (2021) Silencing lncRNA LINC01410 suppresses cell viability yet promotes apoptosis and sensitivity to temozolomide in glioblastoma cells by inactivating PTEN/AKT pathway via targeting miR-370-3p. Immunopharmacol Immunotoxicol Aug 26 doi: 10.1080/08923973.2021.1966031. 2021 Cancer studies Brain cancer
Fujiwara S, et al. (2021) Chemical-gas sterilization of external surface of polymer-based prefilled syringes and its effect on stability of model therapeutic protein. J Pharm Sci Sep 6 doi: 10.1016/j.xphs.2021.09.003. 2021 Structural biology/Protein interactions
Furuyama W, et al. (2021) The Ebola virus soluble glycoprotein contributes to viral pathogenesis by activating the MAP kinase signaling pathway. PLoS Pathog 17(9):e1009937. 2021 Cell signaling
G Hu, et al. (2021) Light-driven CO2 sequestration in Escherichia coli to achieve theoretical yield of chemicals. Nature Catalysis 4: 395–406. 2021 Microorganisms and model organisms
Gao J, et al. (2021) Morroniside Promotes PGC-1α-Mediated Cholesterol Efflux in Sodium Palmitate or High Glucose-Induced Mouse Renal Tubular Epithelial Cells. Biomed Res Int 2021:9942152. 2021 Other
Gao X, et al. (2021) Gambogic acid protects LPS-induced apoptosis and inflammation in a cell model of neonatal pneumonia through the regulation of TrkA/Akt signaling pathway. BMC Pharmacol Toxicol 22(1):28 2021 Cell signaling
Garrido‐Jimenez S, et al. (2021) p53 regulation by MDM2 contributes to self‐renewal and differentiation of basal stem cells in mouse and human airway epithelium. FASEB J 35(9):e21816. 2021 Stem cells
Gaul S, et al. (2021) Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells and induce pro-atherogenic effects. Sci Rep 11(1):15156. Other https://pubmed.ncbi.nlm.nih.gov/34312415/ 2021 Other
Ge X, et al. (2021) Protective effects of naringin on glucocorticoid-induced osteoporosis through regulating the PI3K/Akt/mTOR signaling pathway. Am J Transl Res 13(6):6330-6341. 2021 Cell signaling
George TA, et al. (2021) Liposome-encapsulated anthraquinone improves efficacy and safety in triple negative breast cancer. J Control Release Dec 8 doi: 10.1016/j.jconrel.2021.12.001. 2021 Cancer studies Breast cancer
Grimbert L, et al. (2021) Spatiotemporal AMPKα2 deletion in mice induces cardiac dysfunction, fibrosis and cardiolipin remodeling associated with mitochondrial dysfunction in males only. Biol Sex Differ 12(1):52. 2021 Mitochondrial studies
Groveman BR, et al. (2021) Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt-Jakob disease . Sci Rep 11(1):5165. 2021 Neurobiology
Gu Y, et al. (2021) Therapeutic potential of a novel semi-synthetic-sulfated-polysaccharide to suppress inflammatory mediators in P. gingivalis LPS stimulated human monocytes/macrophages. J Inflamm (Lond) 18(1):26. 2021 Drug mechanism
Guettler J, et al. (2021) Maternal platelets pass interstices of trophoblast columns and are not activated by HLA-G in early human pregnancy.I144:103280. 2021 Other
Guo Y, et al. (2021) miR-23a-3p is involved in drug resistance by directly targeting the influx drug transporter organic anion-transporting polypeptide 2. Childs Nerv Syst Mar 29 doi: 10.1007/s00381-021-05146-3. 2021 Drug mechanism
Han H, et al. (2021) MiR-205 Promotes the Viability, Migration, and Tube Formation of Cervical Cancer Cells In Vitro by Targeting GATA3. Cancer Biother Radiopharm Mar 30 doi: 10.1089/cbr.2020.4184 2021 Cancer studies General
Hanafi M, et al. (2021) Discovery of a Napabucasin PROTAC as an Effective Degrader of the E3 Ligase ZFP91. J Med Chem 64(3):1626-1648. 2021 Cell signaling
Hasan NA, et al. (2021) Measurable genomic changes in Mycobacterium avium subsp. hominissuis after long-term adaptation in Acanthamoeba lenticulata and reduced persistence in in macrophages. J Bacteriol Jan 11 doi: 10.1128/JB.00257-20. 2021 Microorganisms and model organisms
Heltmann-Meyer S, et al. (2021) Gelatin methacryloyl is a slow degrading material allowing vascularization and long-term use in vivo. Biomed Mater Aug 18 doi: 10.1088/1748-605X/ac1e9d. 2021 Method development
Hernandez JJ, et al. (2021) Dodging COVID-19 infection: low expression and localization of ACE2 and TMPRSS2 in multiple donor-derived lines of human umbilical cord-derived mesenchymal stem cells. J Transl Med 19(1):149 2021 Stem cells
Hernandez-Santini AC, et al. (2021) Methamphetamine facilitates pulmonary and splenic tissue injury and reduces T cell infiltration in C57BL/6 mice after antigenic challenge. Sci Rep 11(1):8207 2021 Other
Hesse J, et al. (2021) Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity. Purinergic Signal Dec 27 doi: 10.1007/s11302-021-09832-4. 2021 Other
Hesse J, et al. (2021) Normoxic induction of HIF‐1α by adenosine‐A2BR signaling in epicardial stromal cells formed after myocardial infarction. FASEB J 35(5):e21517 2021 Cell signaling
Hong MJ, et al. (2021) Regulation of Glycosylphosphatidylinositol-Anchored Protein (GPI-AP) Expression by F-Box/LRR-Repeat (FBXL) Protein in Wheat (Triticum aestivum L.). Plants 10(8), 1606. 2021 Plant sciences
Hsueh SC, et al. (2021) N-Adamantyl Phthalimidine: A New Thalidomide-like Drug That Lacks Cereblon Binding and Mitigates Neuronal and Synaptic Loss, Neuroinflammation, and Behavioral Deficits in Traumatic Brain Injury and LPS Challenge. 2021 Neurobiology
Huang CT, et al. (2021) Intravitreal Injection of Long-Acting Pegylated Granulocyte Colony-Stimulating Factor Provides Neuroprotective Effects via Antioxidant Response in a Rat Model of Traumatic Optic Neuropathy. Antioxidants 10(12):1934. 2021 Neurobiology
Huang L, et al. (2021) Circular RNA hsa_circ_0001598 promotes programmed death-ligand-1-mediated immune escape and trastuzumab resistance via sponging miR-1184 in breast cancer cells. Immunol Res Sep 24 doi: 10.1007/s12026-021-09237-w. 2021 Cancer studies Breast cancer
Huang ZN, et al. (2021) Inhibition of p38 Mitogen–Activated Protein Kinase Ameliorates HAP40 Depletion–Induced Toxicity and Proteasomal Defect in Huntington's Disease Model. Mol Neurobiol Jan 25 doi: 10.1007/s12035-020-02280-y. 2021 Neurobiology
Jackson TC, et al. (2021) Hippocampal and Prefrontal Cortical Brain Tissue Levels of Irisin and GDF15 Receptor Subunits in Children. Mol Neurobiol Jan 7 doi: 10.1007/s12035-020-02250-4. 2021 Other
Janke U, et al. (2021) Reconstitution of Functional Integrin αIIbβ3 and Its Activation in Plasma Membrane-Mimetic Lipid Environments. Membranes (Basel) 11(7):499. 2021 Structural biology
Ji L, et al. (2021) Enhancing L-malate production of Aspergillus oryzae by nitrogen regulation strategy. Appl Microbiol Biotechnol Apr 5 doi: 10.1007/s00253-021-11149-6. 2021 Microorganisms and model organisms
Ji Z, et al. (2021) miR-7a Targets Insulin Receptor Substrate-2 Gene and Suppresses Viability and Invasion of Cells in Diabetic Retinopathy Mice via PI3K-Akt-VEGF Pathway. Diabetes Metab Syndr Obes 14:719-728. 2021 Cell signaling
Jia, XB, et al. (2021) Lotus leaf flavonoids induce apoptosis of human lung cancer A549 cells through the ROS/p38 MAPK pathway. Biol Res 54(1):7. 2021 Cancer studies Lung cancer
Jin H, et al. (2021) Gensenoside Rg1 Protects against Lipopolysaccharide-and D-galactose-induced Acute Liver Failure via Suppressing HMGB1-mediated TLR4-NF-κB Pathway. Mol Cell Probes Feb 19 doi: 10.1016/j.mcp.2021.101706. 2021 Drug mechanism
Johar A, et al. (2021) Antibiotic Resistance and Virulence Gene Patterns Associated with Avian Pathogenic Escherichia coli (APEC) from Broiler Chickens in Qatar. Antibiotics 10(5): 564 2021 Microorganisms and model organisms
Jonuscheit S, et al. (2021) PARP Inhibitors Talazoparib and Niraparib Sensitize Melanoma Cells to Ionizing Radiation. Genes (Basel) 12(6):849. 2021 Drug mechanism
Jung HJ, et al. (2021) TAM mediates adaptation of carbapenem-resistant Klebsiella pneumoniae to antimicrobial stress during host colonization and infection. PLoS Pathog 17(2):e1009309. 2021 Microorganisms and model organisms
Jung YS, et al. (2021) Orphan nuclear receptor ERRγ regulates hepatic TGF-β2 expression and fibrogenic response in CCl4-induced acute liver injury. Arch Toxicol Jun 30 doi: 10.1007/s00204-021-03112-1. 2021 Other
Kalogirou C, et al. (2021) MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer. Nat Commun 12(1):5066. 2021 Cancer studies Prostate cancer
Kang H, et al. (2021) Downregulated CLIP3 induces radioresistance by enhancing stemness and glycolytic flux in glioblastoma. J Exp Clin Cancer Res 40(1):282. 2021 Cancer studies Brain cancer
Kang JS, et al. (2021) Ingestion of Bis (2-ethylhexyl) phthalate (DEHP) during adolescence causes depressive-like behaviors through hypoactive glutamatergic signaling in the medial prefrontal cortex. Environ Pollut 289:117978. 2021 Neurobiology
Kasson S, et al. (2021) Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes. PLoS One 16(6):e0254022. 2021 Method development
Kaushal JB, et al. (2021) Repurposing Niclosamide for Targeting Pancreatic Cancer by Inhibiting Hh/Gli Non-Canonical Axis of Gsk3β. Cancers (Basel) 13(13):3105. 2021 Cancer studies Pancreatic cancer
Khan SA, et al. (2021) Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening. Cell Rep 35(11):109233. 2021 Stem cells
Kim DI, et al. (2021) Diesel Exhaust Particulates Enhances Susceptibility of LPS-Induced Acute Lung Injury through Upregulation of the IL-17 Cytokine-Derived TGF-β1/Collagen I Expression and Activation of NLRP3 Inflammasome Signaling in Mice. Biomolecules 11(1):E67. 2021 Cell signaling
Kim EA, et al. (2021) Anti-Obesity Effect of Pine Needle Extract on High-Fat Diet-Induced Obese Mice. Plants (Basel) 10(5):837. 2021 Plant sciences
Kim H, et al. (2022) Baiap3 regulates depressive behaviors in mice via attenuating dense core vesicle trafficking in subsets of prefrontal cortex neurons. Neurobiol Stress 16:100423. 2021 Neurobiology
Kim JY, et al. (2021) Protective Effects of Bee Venom-Derived Phospholipase A2 against Cholestatic Liver Disease in Mice. Biomedicines 9(8):992. 2021 Other
Kim YR, et al. (2021) Isoegomaketone from Perilla frutescens (L.) Britt Stimulates MAPK/ERK Pathway in Human Keratinocyte to Promote Skin Wound Healing. Evidence-Based Complementary and Alternative Medicine Feb 10 doi: 10.1155/2021/6642606. 2021 Drug mechanism
King WT, et al. (2021) Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics. J Biol Chem Sep 13 doi: 10.1016/j.jbc.2021.101196. 2021 Cell signaling
Kipkirui E, et al. (2021) Molecular characterization of enterotoxigenic Escherichia coli toxins and colonization factors in children under five years with acute diarrhea attending Kisii Teaching and Referral Hospital, Kenya. Trop Dis Travel Med Vaccines 7(1):31 2021 Microorganisms and model organisms
Kiss E, et al. (2021) Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines. Int J Mol Sci 22(7):3598. 2021 Cell signaling
Klid S, et al. (2021) The angiogenic properties of human amniotic membrane stem cells are enhanced in gestational diabetes and associate with fetal adiposity. Stem Cell Res Ther 12(1):608. 2021 Stem cells
Knorr DY, et al. (2021) Locust Hemolymph Conveys Erythropoietin-Like Cytoprotection via Activation of the Cytokine Receptor CRLF3. Front Physiol April 09 doi: 10.3389/fphys.2021.648245. 2021 Cell signaling
Kohno T, et al. (2021) Translocation of LSR from tricellular corners causes macropinocytosis at cell–cell interface as a trigger for breaking out of contact inhibition. FASEB J 35(9):e21742 2021 Cancer studies Endometrial cancer
Kono M, et al. (2021) Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery. Cancer Immunol Immunother Apr 18 doi: 10.1007/s00262-021-02940-5. 2021 Cancer studies General
Kouzminova EA, et al. (2021) Ultraviolet-induced RNA: DNA hybrids interfere with chromosomal DNA synthesis. Nucleic Acids Res Mar 10 doi: 10.1093/nar/gkab147. 2021 Other
Kovačević S, et al. (2021) Fructose-Rich Diet Attenuates Stress-Induced Metabolic Disturbances in the Liver of Adult Female Rats. J Nutr Sep 11 doi: 10.1093/jn/nxab294. 2021 Other
Krüger T, et al. (2021) Single-cell motile behaviour of Trypanosoma brucei in thin-layered fluid collectives. Eur Phys J E Soft Matter 44(3):37. 2021 Microorganisms and model organisms
Latina V, et al. (2021) Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease. Acta Neuropathol Commun 9: 38 . 2021 Neurobiology
Lee MH, et al. (2021) Anti-Obesity Effect of Licorice Acetone Extract in a Mouse Model of Obesity Induced by a High-Fat Diet. Food Suppl Biomater Health. 2021 Mar;1(1):e8. 2021 Other
Lee MN, et al. (2021) Luteolin inhibits NLRP3 inflammasome activation via blocking ASC oligomerization. J Nutr Biochem Mar 8 doi: 10.1016/j.jnutbio.2021.108614. 2021 Cell signaling
Lee Y, et al. (2021) Coordinate regulation of the senescent state by selective autophagy. Dev Cell 56(10):1512–1525.e7. 2021 Other
Legscha KJ, et al. (2021) Δ133p53α enhances metabolic and cellular fitness of TCR-engineered T cells and promotes superior antitumor immunity. J Immunother Cancer (6):e001846. 2021 Cancer studies Other
Li J, et al. (2021) Identification and validation of a regulatory mutation upstream of the BMP2 gene associated with carcass length in pigs. Genet Sel Evol 53(1):94. 2021 Other
Li L, et al. (2021) Long non‑coding RNA HAND2‑AS1/miR‑106a/PTEN axis re‑sensitizes cisplatin‑resistant ovarian cells to cisplatin treatment. Mol Med Rep 24(5):762. 2021 Cancer studies General
Li M, et al. (2021) Cytomegalovirus late transcription factor target sequence diversity orchestrates viral early to late transcription. 2021 Microorganisms and model organisms
Li M, et al. (2021) Secreted Expression of mRNA‐Encoded Truncated ACE2 Variants for SARS‐CoV‐2 via Lipid‐Like Nanoassemblies. Adv Mater Jul 18 doi: 10.1002/adma.202101707. 2021 Other
Li N, et al. (2021) Activation of Aquaporin 5 by carcinogenic Helicobacter pylori infection promotes epithelial‐mesenchymal transition via the MEK/ERK pathway. Helicobacter Jul 30 doi: 10.1111/hel.12842. 2021 Cancer studies Gastric cancer
Li P, et al. (2021) Melatonin Attenuates ox-LDL-Induced Endothelial Dysfunction by Reducing ER Stress and Inhibiting JNK/Mff Signaling. Oxid Med Cell Longev Mar 4 doi:10.1155/2021/5589612. 2021 Drug mechanism
Li Q, et al. (2021) In vivo PCSK9 gene editing using an all-in-one self-cleavage AAV-CRISPR system. Mol Ther Methods Clin Dev Feb 9 doi: 10.1016/j.omtm.2021.02.005. 2021 CRISPR
Li S, et al. (2021) Gossypol ameliorates the IL-1β-induced apoptosis and inflammation in chondrocytes by suppressing the activation of TLR4/MyD88/NF-κB pathway via downregulating CX43. Tissue and Cell Aug 10 doi: 10.1016/j.tice.2021.101621. 2021 Cell signaling
Liang M, et al. (2021) Near-infrared fluorescence-guided resection of micrometastases derived from esophageal squamous cell carcinoma using a c-Met-targeted probe in a preclinical xenograft model. J Control Release 332:171–183. 2021 Cancer studies Squamous cell carcinoma
Lin C, et al. (2021) Plac1 promotes nasopharyngeal carcinoma cells proliferation, migration and invasion via Furin/NICD/PTEN pathway. Tissue Cell 69:101480. 2021 Cancer studies General
Lin CC, et al. (2021) Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation. Nat Commun 12(1):3878. 2021 Other
Lin MJ, et al. (2021) An Insulin-like Growth Factor-1 Conjugated Bombyx mori Silk Fibroin Film for Diabetic Wound Healing: Fabrication, Physicochemical Property Characterization, and and Dosage Optimization In Vitro and In Vivo. Pharmaceutics 13(9): 1459. 2021 Drug mechanism
Lin YK, et al. (2021) Pterostilbene Increases LDL Metabolism in HL-1 Cardiomyocytes by Modulating the PCSK9/HNF1α/SREBP2/LDLR Signaling Cascade, Upregulating Epigenetic hsa-miR-335 and hsa-miR-6825, and LDL Receptor Expression. Antioxidants 10(8):1280. 2021 Cell signaling
Lin YM, et al. (2021) Small Molecule Compound Nerolidol attenuates Hypertension induced hypertrophy in spontaneously hypertensive rats through modulation of Mel-18-IGF-IIR signaling. Phytomedicine Jan 4 doi: 10.1016/j.phymed.2020.153450 2021 Other
Lipońska A, MNF Yap. (2021) Hibernation-Promoting Factor Sequesters Staphylococcus aureus Ribosomes to Antagonize RNase R-Mediated Nucleolytic Degradation. mBio Jul 13 doi: 10.1128/mBio.00334-21. 2021 Microorganisms and model organisms
Liu C, et al. (2021) Epigallocatechin gallate (EGCG) attenuates staphylococcal alpha-hemolysin (Hla)-induced NLRP3 inflammasome activation via ROS-MAPK pathways and EGCG-Hla interactions. Int Immunopharmacol 100:108170. 2021 Microorganisms and model organisms
Liu C, et al. (2021) The Downregulation of Placental Lumican Promotes the Progression of Preeclampsia. Reprod Sci Jul 6 doi: 10.1007/s43032-021-00660-w. 2021 Other
Liu D, et al. (2021) The mRNA Tether Model for Activation-Induced Deaminase and its Relevance for Ig Somatic Hypermutation and Class Switch Recombination. DNA Repair (Amst) 110:103271. 2021 DNA repair
Liu Y, et al. (2021) Long noncoding RNA MIR22HG promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-125a-5p that targets N-Myc downstream-regulated gene 2 in late-onset hypogonadism. Lab Invest Aug 26 doi: 10.1038/s41374-021-00645-y. 2021 Cell signaling
Liu Y, et al. (2021) microRNA-221 upregulates the expression of P-gp and Bcl-2 by activating the Stat3 pathway to promote doxorubicin resistance in osteosarcoma cells. 2021 Cell signaling
Loeven NA, et al. (2021) The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection. mBio Sep 28 doi: 10.1128/mBio.02098-21. 2021 Microorganisms and model organisms
Londoño PAC, et al. (2021) Is mRNA decapping by ApaH like phosphatases present in eukaryotes beyond the Kinetoplastida? BMC Ecol Evol 21(1):131. 2021 Other
Lu L, et al. (2021) Therapeutic Effects of Sodium Para-Aminosalicylic Acid on Cognitive Deficits and Activated ERK1/2-p90RSK/NF-κB Inflammatory Pathway in Pb-Exposed Rats. Biol Trace Elem Res Aug 16 doi: 10.1007/s12011-021-02874-0. 2021 Neurobiology
Lu Z, et al. (2021) PP2A protects podocytes against Adriamycin-induced injury and epithelial-to-mesenchymal transition via suppressing JIP4/p38-MAPK pathway. Cytotechnology Aug 13 doi: 10.1007/s10616-021-00484-1. 2021 Cell signaling
Martire A, et al. (2021) P2X7 Receptor Agonist 2′(3′)-O-(4-Benzoylbenzoyl) ATP Differently Modulates Cell Viability and Corticostriatal Synaptic Transmission in Experimental Models of Huntington’s Disease. Front Pharmacol Feb 19 doi: 10.3389/fphar.2020.633861. 2021 Neurobiology
Meng J, et al. (2021) MiR-15a-5p targets FOSL1 to inhibit proliferation and promote apoptosis of keratinocytes via MAPK/ERK pathway. J Tissue Viability Sept 1 doi: 10.1016/j.jtv.2021.08.006. 2021 Cell signaling
Miyake T, et al. (2021) Nucleolar localization of c-Jun. FEBS J Sep 9 doi: 10.1111/febs.16187. 2021 Structural biology/Protein interactions
MOHIUDDIN MD, et al. (2021) Cisplatin Activates the Growth Inhibitory Signaling Pathways by Enhancing the Production of Reactive Oxygen Species in Non-small Cell Lung Cancer Carrying an an EGFR Exon 19 Deletion. Cancer Genomics Proteomics 18(3 Suppl):471-486 2021 Cancer studies Lung cancer
Mohiuddin MD, et al. (2021) Cisplatin and Pemetrexed Have Distinctive Growth-inhibitory Effects in Monotherapy and Combination Therapy on KRAS-dependent A549 Lung Cancer Cells. Cancer Genomics Proteomics 18(4):579-590. 2021 Cancer studies Lung cancer
Mohiuddin MD, et al. (2021) Paclitaxel Impedes EGFR-mutated PC9 Cell Growth via Reactive Oxygen Species-mediated DNA Damage and EGFR/PI3K/AKT/mTOR Signaling Pathway Suppression. Cancer Genomics Proteomics 18(5):645-659. 2021 Cell signaling
Mohiuddin MD, et al. (2021) The Mechanisms of the Growth Inhibitory Effects of Paclitaxel on Gefitinib-resistant Non-small Cell Lung Cancer Cells. Cancer Genomics Proteomics 18(5):661-673. 2021 Cancer studies Lung cancer
Munis AM, et al. (2021) RNA-Seq Analysis of the Human Surfactant Air-Liquid Interface Culture Reveals Alveolar Type II Cell-like Transcriptome. Mol Ther Methods Clin Dev Nov 24 doi: 10.1016/j.omtm.2021.11.06. 2021 Other
Murata K, et al. (2021) Efficient induction of proximity-dependent labeling by biotin feeding in BMAL1-BioID knock-in mice. J Biochem May 12 doi: 10.1093/jb/mvab059 2021 Method development
Nabar NR, et al. (2021) LRRK2 is required for CD38-mediated NAADP-Ca2+ signaling and the downstream activation of TFEB (transcription factor EB) in immune cells. Autophagy Jul 27 doi: 10.1080/15548627.2021.1954779. 2021 Cell signaling
Nagae F, et al. (2021) The lane-switch mechanism for nucleosome repositioning by DNA translocase. Nucleic Acids Res Aug 7 doi: 10.1093/nar/gkab664. 2021 Structural biology and protein interaction
Nakase I, et al. (2021) Environmental pH stress influences cellular secretion and uptake of extracellular vesicles. FEBS Open Bio Feb 3 doi: 10.1002/2211-5463.13107. 2021 Other
Negatu DA, et al. (2021) Piperidine-4-carboxamides target DNA gyrase in Mycobacterium abscessus. Antimicrob Agents Chemother May 17 doi: 10.1128/AAC.00676-21. 2021 Microorganisms and model organisms
Nelson JW, et al. (2021) The gut microbiome contributes to blood‐brain barrier disruption in spontaneously hypertensive stroke prone rats. FASEB J 35(2):e21201. 2021 Microorganisms and model organisms
Niyonizigiye I, et al. (2021) Aspilia africana CD Adams inhibits the production of lipopolysaccharide-induced inflammatory mediators in murine macrophage RAW264. 7 cells by suppressing the NF-κB and PI3K/Akt pathways. S Afr J Bot 141: 83–89 2021 Plant sciences
Nußbaum P, et al. (2021) The archaeal protein SepF is essential for cell division in Haloferax volcanii. Nat Commun 12(1):3469. 2021 Microorganisms and model organisms
Okazawa M, et al. (2021) A 3-styrylchromone converted from trimebutine 3D pharmacophore possesses dual suppressive effects on RAGE and TLR4 signaling pathways. Biochem Biophys Res Commun 566:1-8. 2021 Cell signaling
Oyama T, et al. (2021) Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells. Biochimie Sep 15 doi: 10.1016/j.biochi.2021.09.007. 2021 Cancer studies Skin cancer
Parashar P, et al. (2021) Targeted biologic inhibition of both tumor cell-intrinsic and intercellular CLPTM1L/CRR9 mediated chemotherapeutic drug resistance. NPJ Precis Oncol 5(1):16. 2021 Cancer studies Ovarian cancer
Park SK, et al. (2021) Ecklonia cava Attenuates PM2. 5-Induced Cognitive Decline through Mitochondrial Activation and Anti-Inflammatory Effect. Mar Drugs 19(3):131. 2021 Neurobiology
Pastuschek J, et al. (2021) Molecular characteristics of established trophoblast-derived cell lines. Placenta Mar 4 doi: 10.1016/j.placenta.2021.02.022. 2021 Other
Pourfarjam Y, et al. (2021) Structural and biochemical analysis of human ADP-ribosyl-acceptor hydrolase 3 (ARH3) reveals the basis of metal selectivity and different roles for the two Mg ions. J Biol Chem Apr 21 doi: 10.1016/j.jbc.2021.100692 2021 Structural biology/protein interactions
Purves TD, et al. (2021) Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia. Mol Brain 14(1):96. 2021 Neurobiology
Qadeer A, et al. (2021) Transcriptional profiles of genes potentially involved in extracellular vesicle biogenesis in Schistosoma japonicum. Acta Trop 217:105851. 2021 Other
Qin D, et al. (2021) LINC01207 promotes prostate cancer progression by sponging miR‑1182 to upregulate AKT3. Oncology Letters Dec 21 doi: 10.3892/ol.2021.13175. 2021 Cancer studies General
Qiu H, et al. (2021) miR-30b-5p inhibits cancer progression and enhances cisplatin sensitivity in lung cancer through targeting LRP8. Apoptosis Mar 29 doi: 10.1007/s10495-021-01665-1. 2021 Cancer studies Lung cancer
Qiu X, et al. (2021) Forkhead box O1 targeting replication factor C subunit 2 expression promotes glioma temozolomide resistance and survival. Ann Transl Med (8):692 2021 Cancer studies Brain cancer
Qiu Y, et al. (2021) RNA binding protein MEX3A controls G1/S transition via regulating the RB/E2F pathway in clear cell renal cell carcinoma. Mol Ther Nucleic Acids 27:241-255 2021 Cancer studies General
Radhakrishnan K, et al. (2021) Orphan nuclear receptor ERR-γ regulates hepatic FGF23 production in acute kidney injury. Proc Natl Acad Sci USA 118(16):e2022841118. 2021 Other
Rao Y, et al. (2021) NeuroD1 induces microglial apoptosis and cannot induce microglia-to-neuron cross-lineage reprogramming. Neuron doi: 10.1016/j.neuron.2021.11.008. 2021 Neurobiology
Ratti S, et al. (2021) Lamin B1 Accumulation's Effects on Autosomal Dominant Leukodystrophy (ADLD): Induction of Reactivity in the Astrocytes. Cells 10(10):2566. 2021 Neurobiology
Rehnitz J, et al. (2021) FMR1 expression in human granulosa cells and variable ovarian response: control by epigenetic mechanisms. Mol Hum Reprod Jan 25 doi: 10.1093/molehr/gaab001. 2021 Other
Rensi N, et al. (2021) Evaluation of TFR-1 Expression in Feline Mammary Cancer and In Vitro Antitumor Efficacy Study of Doxorubicin-Loaded H-Ferritin Nanocages. Cancers 13(6): 1248. 2021 Cancer studies Breast cancer
Roberts A, et al. (2021) Electroactive reduced graphene oxide for highly sensitive detection of secretory non-structural 1 protein: A potential diagnostic biomarker for Japanese encephalitis virus. Biosens Bioelectron 198:113837. 2021 Disease study Biomarker research
Rodriguez F, et al. (2021) Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. PLoS Negl Trop Dis 15(2):e0009147. 2021 Microorganisms and model organisms
Russell JC, et al. (2021) Generation and characterization of a tractable C. elegans model of tauopathy. Geroscience Sep 18 doi: 10.1007/s11357-021-00436-9. 2021 Neurobiology
Ryota C. et al. (2021) Divergence in chondrogenic potential between in vitro and in vivo of adipose-and synovial-stem cells from mouse and human. Stem Cell Res Ther 12(1):405. 2021 Stem cells
Santerre M, et al. (2021) HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons. Autophagy Apr 23 doi: 10.1080/15548627.2021.1915641. 2021 Neurobiology
Santos MF, et al. (2021) Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum. J Extracell Vesicles 10(10):e12132. 2021 Other
Savitr C, et al. (2021) M2 Macrophage-Derived Concentrated Conditioned Media Significantly Improves Skin Wound Healing. Tissue Eng Regen Med Dec 28. doi: 10.1007/s13770-021-00414-4. 2021 Other
Senji Laxme RR, et al. (2021) Biogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy. PLoS Negl Trop Dis 15(2):e0009150. 2021 Other
Seno S, et al. (2021) β-Thujaplicin Enhances TRAIL-Induced Apoptosis via the Dual Effects of XIAP Inhibition and Degradation in NCI-H460 Human Lung Cancer Cells. Medicines 8(6):26. 2021 Cancer studies Lung cancer
Shih HJ, et al. (2021) Differential expression of hypoxia-inducible factors related to the invasiveness of epithelial ovarian cancer. Sci Rep 11(1):22925. 2021 Cancer studies General
Shih HJ, et al. (2021) Simultaneous Inhibition of Three Major Cytokines and Its Therapeutic Effects: A Peptide-Based Novel Therapy against Endotoxemia in Mice. J Pers Med 11(5): 436. 2021 Drug mechanism
Shirsath K, et al. (2021) Chronic photoperiodic manipulation induced chronodisruption upregulates HSP60 during early pro-atherogenic remodeling in thoracic aorta of C57BL/6J mice. The Journal of Basic and Applied Zoology 82:9. 2021 Other
Shirsath K, et al. (2021) HSP60 knockdown exerts differential response in endothelial cells and monocyte derived macrophages during atherogenic transformation. Sci Rep 11(1):1086. 2021 Other
Siwach M, et al. (2021) An organelle-tethering mechanism couples flagellation to cell division in bacteria. Dev Cell Feb 17 doi: 10.1016/j.devcel.2021.01.013. 2021 Microorganisms and model organisms
Skertich NJ, et al. (2021) Expression of Programmed Death Ligand 1 in Drug Resistant Osteosarcoma: An Exploratory Study. Surg Open Sci doi: 10.1016/j.sopen.2021.07.001. 2021 Cancer studies General
Slominski AT, et al. (2021) Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs). Sci Rep 11(1):8002. 2021 Other
Souza COS, et al. (2021) NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses. iScience May 18 doi.org/10.1016/j.isci.2021.102548 2021 Other
Spampinato S, et al. (2021) Protective effect of the sphingosine-1 phosphate receptor agonist siponimod on disrupted blood brain barrier function. Biochem Pharmacol 186:114465. 2021 Neurobiology
Srinivasan A, et al. (2021) Preclinical Development of Plant‐based Oral Immune Modulatory Therapy for Hemophilia B. Plant Biotechnol J May 5 doi: 10.1111/pbi.13608 2021 Other
Sripathi SR, et al. (2021) Epithelial to mesenchymal transition (EMT) of human stem cell-derived retinal pigment epithelium shares commonalities with malignancy-associated EMT: a proteomic analysis. Mol Cell Proteomics Aug 26 doi: 10.1016/j.mcpro.2021.100131. 2021 Stem cells
Srivastava T, et al. (2021) A mouse model of prenatal exposure to Interleukin-6 to study the developmental origin of health and disease. Sci Rep 11(1):13260. 2021 Other
Stabel JR, et al. (2021) Reduced tissue colonization of Mycobacterium avium subsp. paratuberculosis in neonatal calves vaccinated with a cocktail of recombinant proteins. Vaccine 39(23):3131–3140 2021 Other
Su N , et al. (2021) Circ_0001666 affects miR-620/WNK2 axis to inhibit breast cancer progression. Genes Genomics Jun 1 doi: 10.1007/s13258-021-01114-y 2021 Cancer studies Breast cancer
Sun L, et al. (2021) Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation via NLRP3 signal inhibition in aged mice. CNS Neurosci Ther Dec 23. doi: 10.1111/cns.13784. 2021 Neurobiology
Sunagar K, et al. (2021) A Wolf in Another Wolf's Clothing: Post-Genomic Regulation Dictates Venom Profiles of Medically-Important Cryptic Kraits in India. Toxins (Basel) 13(1):69. 2021 Other
Suthon S, et al. (2021) Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in osteoblasts. Am J Hum Genet Dec 2 doi: 10.1016/j.ajhg.2021.11.018. 2021 Disease study Biomarker research
Suzuki Y, et al. (2021) Pathogenicity and genomic features of vapN-harboring Rhodococcus equi isolated from human patients. Int J Med Microbiol July 2 doi: 10.1016/j.ijmm.2021.151519. 2021 Other
Switzer CH, et al. (2021) Cysteine trisulfide oxidizes protein thiols and induces electrophilic stress in human cells. Redox Biol 47:102155. 2021 Cell signaling
Szatmári Á, et al. (2021) A pattern-triggered immunity-related phenolic, acetosyringone, boosts rapid inhibition of a diverse set of plant pathogenic bacteria. BMC Plant Biol 21(1):153. 2021 Plant sciences
Tada T, et al. (2021) Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes. mBio Jun 1 doi: 10.1128/mBio.00696-21. 2021 Other
Takahashi M, et al. (2021) Quick and Easy Assembly of a One-Step qRT-PCR Kit for COVID-19 Diagnostics Using In-House Enzymes. ACS Omega 6(11): 7374–7386. 2021 Method development
Takahashi Y, et al. (2021) Direct administration of the non-competitive interleukin-1 receptor antagonist rytvela transiently reduced intrauterine inflammation in an extremely preterm sheep model of chorioamnionitis. PLoS One 16(9):e0257847. 2021 Other
Tanaka H, et al. (2021) Human colorectal cancer-associated carbohydrate antigen on annexin A2 protein. J Mol Med (Berl) Apr 27 doi: 10.1007/s00109-021-02077-z 2021 Cancer studies Collorectal cancer
Tang M, et al. (2021) Glycyrrhetinic acid remodels the tumor microenvironment and synergizes with doxorubicin for breast cancer treatment in a murine model. Nanotechnology Jan 27. doi: 10.1088/1361-6528/abe076. 2021 Cancer studies Breast cancer
Taş İ, et al. (2021) Physciosporin Suppresses Mitochondrial Respiration, Aerobic Glycolysis, and Tumorigenesis in Breast Cancer. Phytomedicine Jul 18 doi: 10.1016/j.phymed.2021.153674. 2021 Cancer studies Breast cancer
Tassone A, et al. (2021) Vesicular Acetylcholine Transporter Alters Cholinergic Tone and Synaptic Plasticity in DYT1 Dystonia. Mov Disord Jun 26 doi: 10.1002/mds.28698 2021 Neurobiology
Teti G, et al. (2021) Cellular senescence in vascular wall mesenchymal stromal cells, a possible contribution to the development of aortic aneurysm. Mech Ageing Dev 197:111515. 2021 Other
Tong X, et al. (2021) RNF144A-AS1 promotes the development of glioma cells by targeting miR-665/HMGA1 axis. Neurosci Lett Sep 21 doi: 10.1016/j.neulet.2021.136259. 2021 Cancer studies General
Toychiev AH, et al. (2021) Gap Junctional Coupling Between Retinal Astrocytes Exacerbates Neuronal Damage in Ischemia-Reperfusion Injury. Invest Ophthalmol Vis Sci 62(14):27. 2021 Neurobiology
Ueda H, et al. (2021) Synthesis of sp [3]-Rich Chiral Bicyclo [3.3. 1] nonanes for Chemical Space Expansion and Study of Biological Activities. Bioorg Med Chem 54:116561. 2021 Other
Urrutia Iñiguez J, et al. (2021) An epilepsy-causing mutation leads to co-translational misfolding of the Kv7. 2 channel. BMC Biol 19(1):109. 2021 Neurobiology
V Kumar, et al. (2021) Polymeric nanomedicine for overcoming resistance mechanisms in hedgehog and Myc-amplified medulloblastoma. Biomaterials 278:121138. 2021 Drug mechanism
Vakilian S, et al. (2021) An engineered microfluidic blood‐brain barrier model to evaluate the anti‐metastatic activity of β‐boswellic acid. Biotechnol J Jul 27 doi: 10.1002/biot.202100044 2021 Cancer studies General
Valenzuela-Muñoz V, et al. (2021) Transcriptome and morphological analysis in Caligus rogercresseyi uncover the effects of Atlantic salmon vaccination with IPath®. 2021 Other
Vester SK, et al. (2021) Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation. J Biol Chem Mar 4 doi: 10.1016/j.jbc.2021.100513. 2021 Structural biology/protein interaction
Wan S, et al. (2021) MicroRNA-140-3p represses the proliferation, migration, invasion and angiogenesis of lung adenocarcinoma cells via targeting TYMS (Thymidylate Synthetase). Bioengineered Nov 24 doi: 10.1080/21655979.2021.2009422 2021 Cancer studies Lung cancer
Wang J, et al. (2021) MicroRNA-532-5p upregulation protects neurological deficits after ischemic stroke through inhibition of BTB and CNC homology 1. Int Immunopharmacol 100:108003. 2021 Neurobiology
Wang K, et al. (2021) Downregulation of DEAD-box helicase 21 (DDX21) inhibits proliferation, cell cycle, and tumor growth in colorectal cancer via targeting cell division cycle 5-like (CDC5L). Bioengineered 12(2):12647-12658. 2021 Cancer studies Colorectal cancer
Wang P, et al. (2021) Loss of haspin suppresses cancer cell proliferation by interfering with cell cycle progression at multiple stages. FASEB J 35(10):e21923. 2021 Cancer studies General
Wang X, et al. (2021) Staphylococcus aureus Extracellular Vesicles: A Story of Toxicity and the Stress of 2020. Toxins (Basel) 13(2):E75. 2021 Microorganisms and model organisms
Wang Y, et al. (2021) MYPT1, regulated by miR-19b-3p inhibits the progression of non-small cell lung cancer via inhibiting the activation of wnt/β-catenin signaling. Life Sci May 5 doi: 10.1016/j.lfs.2021.119573 2021 Cancer studies Lung cancer
Wei, Y et al. (2021) Acacetin ameliorates insulin resistance in obesity mice through regulating Treg/Th17 balance via MiR-23b-3p/NEU1 Axis. BMC Endocr Disord 21(1):57. 2021 Cell signaling
Welch JL, et al. (2021) Human T cells express Angiotensin Converting Enzyme 2 at levels sufficient to interact with the SARS-CoV-2 Spike protein. J Infect Dis Dec 16 doi: 10.1093/infdis/jiab595. 2021 Microorganisms and model organisms
Wen L, et al. (2021) The lignan sesamin suppresses TRIM44 and exerts antitumor activity to esophageal squamous cell carcinoma. Chem Biol Drug Des Aug 19. doi: 10.1111/cbdd.13937. 2021 Cancer studies Squamous cell carcinoma
Wu CL, et al. (2021) Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis. Nat Commun 12(1):362. 2021 Stem cells
Xu J, et al. (2021) Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons. J Neuroinflammation 18(1):106 2021 Neurobiology
Yahya G, et al. (2021) Profiling the physiological pitfalls of anti‐hepatitis C direct‐acting agents in budding yeast. Microb Biotechnol Aug 11  doi: 10.1111/1751-7915.13904. 2021 Microorganisms and model organisms
Yan L, et al. (2021) Fisetin ameliorates atherosclerosis by regulating PCSK9 and LOX‑1 in apoE‑/‑mice. Exp Ther Med 21:25. 2021 Drug mechanism
Yang C, et al. (2021) Nuclear IGF1R interacts with NuMA and regulates 53BP1‑dependent DNA double‑strand break repair in colorectal cancer. Oncol Rep 46(2):168. 2021 Cancer studies Colorectal cancer
Yang W, et al. (2021) Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response. Biochem Pharmacol 195:114863. 2021 Other
Yang X, et al. (2021) Identification and verification of HCAR3 and INSL5 as new potential therapeutic targets of colorectal cancer. World J Surg Oncol 19(1):248. 2021 Cancer studies Colorectal cancer
Yang Y, et al. (2021) Dysregulated APP expression and α-secretase processing of APP is involved in manganese-induced cognitive impairment. Ecotoxicol Environ Saf 220:112365. 2021 Other
Yankel C, et al. (2020) Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST. Sci Rep 10(1):15791. 2021 Method development
Yazgili AS, et al. (2021) In-gel proteasome assay to determine the activity, amount, and composition of proteasome complexes from mammalian cells or tissues. STAR Protoc 2(2): 100526 2021 Method development
Yeini E, et al. (2021) P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression. Nat Commun 12(1):1912. 2021 Cancer studies Brain cancer
Yi H, et al. (2021) Knockdown of long non‑coding RNA DLEU2 suppresses idiopathic pulmonary fibrosis by regulating the microRNA‑369‑3p/TRIM2 axis. Int J Mol Med 47(5):80. 2021 Other
Yoo SK, et al. (2021) Immature Persimmon Suppresses Amyloid Beta (Aβ) Mediated Cognitive Dysfunction via Tau Pathology in ICR Mice. Curr Issues Mol Biol 43(1):405-422. 2021 Neurobiology
Young N, et al. (2021) Biallelic SYNE2 Missense Mutations Leading to Nesprin-2 Giant Hypo-Expression Are Associated with Intellectual Disability and Autism. Genes 12(9): 1294. 2021 Neurobiology
Yousefzadeh MJ, et al. (2021) An aged immune system drives senescence and ageing of solid organs. Nature May 12 doi: 10.1038/s41586-021-03547-7 2021 Other
Yu C, et al. (2021) Protective Effect and Mechanism of Schisandra Chinensis Extract on Retinal Photoreceptor Cell Injury. Farmacia 69(1): 107-112. 2021 Other
Yu S, et al. (2021) A Protein from Dioscorea polystachya (Chinese Yam) Improves Hydrocortisone-Induced Testicular Dysfunction by Alleviating Leydig Cell Injury via Upregulation of the Nrf2 Pathway. Oxid Med Cell Longev 2021:3575016 2021 Cell signaling
Yu Y, et al. (2021) Prodrug Nanomedicine Inhibits Chemotherapy-Induced Proliferative Burst by Altering the Deleterious Intercellular Communication. ACS Nano Jan 7 doi: 10.1021/acsnano.0c07113. 2021 Cancer studies General
Yuk H, et al. (2021) Necrostatin-1 Prevents Ferroptosis in a RIPK1-and IDO-Independent Manner in Hepatocellular Carcinoma. Antioxidants 10(9): 1347. 2021 Cancer studies Liver cancer
Zabegina L, et al. (2021) A New Approach for Prostate Cancer Diagnosis by miRNA Profiling of Prostate-Derived Plasma Small Extracellular Vesicles. Cells 10(9): 2372. 2021 Cancer studies General
Zhai L, et al. (2021) Overexpressed Versican Promoted Cell Multiplication, Migration and Invasion in Gastric Cancer. Tissue Cell 73:101611. 2021 Cancer studies Gastric cancer
Zhang L, et al. (2021) MiR-22 regulated T cell differentiation and hepatocellular carcinoma growth by directly targeting Jarid2. Am J Cancer Res 11(5):2159-2173. 2021 Cancer studies Liver cancer
Zhang M, et al. (2021) Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases. Nat Commun 12(1):2344. 2021 Other
Zhang X, et la. (2021) Transcranial photobiomodulation therapy ameliorates perioperative neurocognitive disorder through modulation of mitochondrial function in aged mice. Neuroscience Dec 31 doi: 10.1016/j.neuroscience.2021.12.033. 2021 Neurobiology
Zhang Y, et al. (2021) Cerebellar Kv3. 3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1. Nat Commun 12(1):1731 2021 Cell signaling
Zhang Y, et al. (2021) Lycium barbarum Polysaccharides Promotes Mitochondrial Biogenesis and Energy Balance in a NAFLD Cell Model. Chin J Integr Med Dec 7 doi: 10.1007/s11655-021-3309-6. 2021 Mitochondrial studies
Zhang Y, et al. (2021) Overexpression of miR-99a Alleviates Intestinal Mucosal Barrier Injury in Rats with Severe Acute Pancreatitis. J Interferon Cytokine Res 41(2):72-80. 2021 Other
Zhang YY, et al. (2021) Chimeric antigen-guiding extracellular vesicles eliminate antigen-specific Th2 cells in subjects with food allergy. World Allergy Organ J 14(3): 100522. 2021 Other
Zhao Y, et al. (2021) Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF‐κB signaling. Immun Inflamm Dis Jun 5 doi: 10.1002/iid3.465. 2021 Cell signaling
Zhou X, et al. (2021) UTMD-mediated delivery of MiR-21-5p inhibitor suppresses the development of lung cancer. Tissue Cell 74:101719. 2021 Cancer studies Lung cancer
Zhu J, et al. (2021) Predictive Models for HCC Prognosis, Recurrence Risk, and Immune Infiltration Based on Two Exosomal Genes: MYL6B and THOC2. J Inflamm Res 14:4089-4109. 2021 Cancer studies Liver cancer
Zimmer A, et al. (2021) Thioredoxin system activation is associated with the progression of experimental pulmonary arterial hypertension. Life Sci 284:119917. 2021 Cell signaling
Adhikari A and Davie JK (2020) The PRC2 complex directly regulates the cell cycle and controls proliferation in skeletal muscle. Cell Cycle Aug 20 doi: 10.1080/15384101.2020.1806448. 2020 Other
Adhikari XY, et al. (2020) IFN-γ and CIITA modulate IL-6 expression in skeletal muscle. Cytokine: X (2)2:100023 2020 Other
Ali G, et al. (2020) Keratinocytes derived from patient-specific induced pluripotent stem cells recapitulate the genetic signature of psoriasis disease. Stem Cells Dev Jan 29 doi: 10.1089/scd.2019.0150. 2020 Disease study: Biomarker research
Almacellas E, et al. (2020) Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability. Autophagy Jun 23 doi: 10.1080/15548627.2020.1764727.  2020 Other
An N, et al. (2020) SEZ6L2 Knockdown Impairs Tumour Growth by Promoting Caspase-Dependent Apoptosis in Colorectal Cancer. J Cell Mol Med Feb 27 doi: 10.1111/jcmm.15082. 2020 Cell signaling
Arreal L, et al. (2020) Targeting PML in Triple Negative Breast Cancer Elicits Growth Suppression and Senescence. Cell Death Differ 27:1186–1199. 2020 Cancer Breast
Barilli A, et al. (2020) Organic Cation Transporters (OCTs) in EpiAirway™, A Cellular Model of Normal Human Bronchial Epithelium. Biomedicines 8(5):127. 2020 Other
Bartish M, et al. (2020) MNK2 governs the macrophage antiinflammatory phenotype. Proc Natl Acad Sci U S A Oct 19 doi: 10.1073/pnas.1920377117. 2020 Cell signaling
Baxter K, et al. (2020) Towards defining global ecotypes of the toxic cyanobacterium Raphidiopsis raciborskii. Applied Phycology Aug 6 doi: 10.1080/26388081.2020.1740891. 2020 Microorganisms and model organisms
Bayazid AB, et al. (2020) Antioxidant, Anti-inflammatory, and Antiproliferative Activity of Mori Cortex Radicis Extracts. Natural Prod Comm 15(1):1–8. 2020 Other
Bhattacharjee P, et al. (2020) Synthetic Carboline Compounds Targeting Protein: Biophysical and Biological Perspective. J Biomol Struct Dyn June 1 doi: 10.1080/07391102.2020.1769732. 2020 Other
Bittmann J, et al. (2020) An Advanced Cell Cycle Tag Toolbox Reveals Principles Underlying Temporal Control of Structure-Selective Nucleases. Elife 9:e52459. 2020 Other
Bonar MM, et al. (2020) Nanoscale flow cytometry reveals interpatient variability in HIV protease activity that correlates with viral infectivity and identifies drug-resistant viruses. Sci Rep 10(1):18101. 2020 Method development
Bouza AA, et al. (2020) Sodium channel β1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis. J Biol Chem 295(30):10380–10393. 2020 Other
Chen D, et al. (2020) Cancer Cell Membrane-Decorated Zeolitic-Imidazolate Frameworks Codelivering Cisplatin and Oleanolic Acid Induce Apoptosis and Reversed Multidrug Resistance on Bladder Carcinoma Cells. ACS Omega 5(2):995-1002. 2020 Cancer Bladder
Chen D, et al. (2020) Downregulating miR-96-5p promotes proliferation, migration, and invasion, and inhibits apoptosis in human trophoblast cells via targeting DDAH1. Reprod BioI 21(1):100474. 2020 Cell signaling
Chen Q, et al. (2020) Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair. Cell Rep 31(13):107828. 2020 Other
Cheng L, et al. (2020) Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway. Metabolites 10(3):E90. 2020 Cell signaling
Ciu S, et al. (2020) LncRNA MAGI2-AS3 is down-regulated in intervertebral disc degeneration and participates in the regulation of FasL expression in nucleus pulposus cells. BMC Musculoskelet Disord 21:149. 2020 Other
Darvish-Ghane S, et al. (2020) D1 receptors in the anterior cingulate cortex modulate basal mechanical sensitivity threshold and glutamatergic synaptic transmission. Mol Brain 13(1):121. 2020 Neurobiology
Darvishi E, et al. (2020) Molecular Mechanisms of Guadecitabine Induced FGFR4 Down Regulation in Alveolar Rhabdomyosarcomas. Neoplasia 22(7):274−282. 2020 Cancer General
de Oliveira BH, et al. (2020) ET-B receptors involvement in peripheral opioid analgesia induced by light-emitting diode photobiomodulation in male and female mice. J Photochem Photobiol B 214:112104. 2020 Other
Delvaux NA, et al. (2020) Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Anal Biochem Aug 9 doi: 10.1016/j.ab.2020.113895. 2020 Method development
Ding Q, et al. (2020) Light-powered Escherichia Coli Cell Division for Chemical Production. Nat Commun 11:2262. 2020 Microorganisms and model organisms
Dopie J, et al. (2020) Tyramide signal amplification mass spectrometry (TSA-MS) ratio identifies nuclear speckle proteins. J Cell Biol 219(9):e201910207. 2020 Method development
Du P, et al. (2020) Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer. Cell Death Dis 11(9):761. 2020 Cancer studies: Breast cancer
Dye BK, et al. (2020) Smooth Muscle α-Actin Expression in Mitral Valve Interstitial Cells is Important for Mediating Extracellular Matrix Remodeling. J Cardiovasc Dev Dis 7(3):E32. 2020 Other
Ebelt ND, et al. (2020) 5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma. Front Immunol 11:538. 2020 Cancer Pancreatic
Eccardt AM, et al. (2020) A Peroxidase Mimetic Protects Skeletal Muscle Cells From Peroxide Challenge and Stimulates Insulin Signaling. Am J Physiol Cell Physiol 318(6):C1214−C1225. 2020 Other
Eichler CE, et al. (2020) Compartmentalized oskar degradation in the germ plasm safeguards germline development. Elife 9:e49988. 2020 Other
Elsayed AK, et al. (2020) Derivation of a Human Induced Pluripotent Stem Cell Line (QBRIi007-A) From a Patient Carrying a Homozygous Intronic Mutation (c.613-7T>G) in the SLC2A2 Gene. Stem Cell Res 44:101736. 2020 Stem cells
Eltai NO, et al. (2020) Antibiotic Resistance and Virulence Patterns of Pathogenic Escherichia Coli Strains Associated With Acute Gastroenteritis Among Children in Qatar. BMC Microbiol 20(1):54. 2020 Microorganisms and model organisms
Esaki M, et al. (2020) The effect of dihydropyrazines on lipopolysaccharide-stimulated human hepatoma HepG2 cells via regulating the TLR4-MyD88-mediated NF-κB signaling pathway. J Toxicol Sci 45(7):401–409. 2020 Cell signaling
Fan Q, et al. (2020) Paeoniflorin Modulates Gut Microbial Production of Indole-3-lactate and Epithelial Autophagy to Alleviate Colitis in Mice. Phytomedicine Sept 19 doi: 10.1016/j.phymed.2020.153345 2020 Other
Foliaki ST, et al. (2020) Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease. 2020 Disease study: Biomarker research
Forstner D, et al. (2020) Platelet-derived factors impair placental chorionic gonadotropin beta-subunit synthesis. J Mol Med (Berl) 98(2):193−207. 2020 Cell signaling
Francis R, et al. (2020) Glycolytic Inhibitor 2-deoxyglucose Suppresses Inflammatory Response in Innate Immune Cells and Experimental Staphylococcal Endophthalmitis. Exp Eye Res 197:108079. 2020 Other
Furuyama W, et al. (2020) A complement component C1q-mediated mechanism of antibody-dependent enhancement of Ebola virus infection. PLoS Negl Trop Dis 14(9):e0008602. 2020 Microorganisms and model organisms
Fuseya S, et al. (2020) Mice lacking core 1-derived O-glycan in podocytes develop transient proteinuria, resulting in focal segmental glomerulosclerosis. Biochem Biophys Res Comm 523(4):1007−1013. 2020 Other
Gahamanyi N, et al. (2020) Susceptibility of Campylobacter Strains to Selected Natural Products and Frontline Antibiotics. Antibiotics (Basel) 9(11):E790. 2020 Microorganisms and model organisms
Gan C, et al. (2020) Untargeted metabolomics study and pro-apoptotic properties of B-norcholesteryl benzimidazole compounds in ovarian cancer SKOV3 cells. J Steroid Biochem Mol Biol 202:105709. 2020 Cancer studies Ovarian
Gibbons GS, et al. (2020) Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library. Eur J Med Chem 189:112023. 2020 Method development
Goldstein T, et al. (2020) Spillover of ebolaviruses into people in Eastern Democratic Republic of Congo prior to the 2018 Ebola virus disease outbreak. One Health Outlook 2(1):21. 2020 Other
Guo J, et al. (2020) RNA-binding proteins tristetraprolin and human antigen R are novel modulators of podocyte injury in diabetic kidney disease. Cell Death Dis 11(6):413. 2020 Other
Han HJ, et al. (2020) Anti-Melanogenic Effect of Ethanolic Extract of Sorghum bicolor on IBMX-Induced Melanogenesis in B16/F10 Melanoma Cells. Nutrients 12(3):E832. 2020 Cancer Skin
Han S, et al. (2020) Ultrasound Stimulation Increases Neurite Regeneration in Injured Dorsal Root Ganglion Neurons through Mammalian Target of Rapamycin Activation. Brain Sci 10(7):E409. 2020 Cell signaling
Harmouch E, et al. (2020) Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes. Sci Rep 10(1):13750 2020 Cancer studies Brain cancer
Hasan ASH, et al. (2020) Characterization of a bicistronic knock-in reporter mouse model for investigating the role of CABLES2 in vivo. Exp Anim Aug 11 doi: 10.1538/expanim.20-0063. 2020 Microorganisms and model organisms
Hashiguchi H, et al. (2020) Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with α1, 2-fucose in the small intestine. Arch Biochem Biophys 695:108653. 2020 Microorganisms and model organisms
He X, et al. (2020) Hypoxia improved vasculogenesis in distraction osteogenesis through Mesenchymal-Epithelial transition (MET), Wnt/β-catenin signaling pathway, and autophagy. Acta Histochemica 122:151593. 2020 Cell signaling
Hong MJ, et al. (2020) Isolation and characterization of kelch repeat-containing F-box proteins from colored wheat. Mol Biol Rep 47(2):1129−1141. 2020 Plant sciences
Houston R, et al. (2020) Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses. PLoS Biol 18(11):e3000981. 2020 CRISPR
Huo J, et al. (2020) Rewiring carbon flux in Escherichia coli using a bifunctional molecular switch. Metab Eng 61:47–57. 2020 Microorganisms and model organisms
Ihara K, et al. (2020) A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice. Sci Rep 10(1):17894. 2020 Other
Jung Y and Yoon M. (2020) Oxytocin Receptor Expression in Stallion Testes and Epididymides. Domest Anim Endocrinol Sept 12 doi: 10.1016/j.domaniend.2020.106562 2020 Other
JY Kim JY, et al. (2020) Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice. Antioxidants (Basel) 9(12):E1271. 2020 Other
Kalchiem-Dekel O, et al. (2020) Apolipoprotein E Signals via TLR4 to Induce CXCL5 Secretion by Asthmatic Airway Epithelial Cells. Am J Respir Cell Mol Biol Apr 27 doi: 10.1165/rcmb.2019-0209OC. 2020 Cell signaling
Kang DR, Shim KS. (2020) Early heat exposure effect on the heat shock proteins in broilers under acute heat stress. Poult Sci Dec 26 doi:10.1016/j.psj.2020.12.061. 2020 Other
Kim D, et al. (2020) Muscle-derived TRAIL negatively regulates myogenic differentiation. Exp Cell Res Jul 6 doi: 10.1016/j.yexcr.2020.112165. 2020 Cell signaling
Kim DH, et al. (2020) TGF-β1-mediated Repression of SLC7A11 Drives Vulnerability to GPX4 Inhibition in Hepatocellular Carcinoma Cells. Cell Death Dis 11(5):406. 2020 Cancer Liver
Kim HY, et al. (2020) Epidermal growth factor (EGF)-based activatable probe for predicting therapeutic outcome of an EGF-based doxorubicin prodrug. J Control Release Aug 28 doi: 10.1016/j.jconrel.2020.08.046. 2020 Drug mechanism
Kim HY, et al. (2020) Protective Effect of Vitis labrusca Leaves Extract on Cardiovascular Dysfunction through HMGB1-TLR4-NFκB Signaling in Spontaneously Hypertensive Rats. 2020 Other
Kim J, et al. (2020) Gene expression amplification by nuclear speckle association. J Cell Bio 219:e201904046. 2020 Other
Kim J, et al. (2020) Lung-targeted Delivery of TGF-β Antisense Oligonucleotides to Treat Pulmonary Fibrosis. J Control Release 322:108−121. 2020 Method development
Kim JJ, et al. (2020) Overexpression of a proton pumping gene OVP1 enhances salt stress tolerance, root growth and biomass yield by regulating ion balance in rice (Oryza sativa L.). Environ Exp Bot 175:104033. 2020 Plant sciences
Kim JM, et al. (2020) Anti-Amnesic Effect of Walnut via the Regulation of BBB Function and Neuro-Inflammation in Aβ1-42-Induced Mice. Antioxidants (Basel) 9(10):E976. 2020 Neurobiology
Kim JM, et al. (2020) Matcha Improves Metabolic Imbalance-Induced Cognitive Dysfunction. Oxid Med Cell Longev 2020: 8882763. 2020 Other
Kim JY, et al. (2020) Kahweol Ameliorates Cisplatin-Induced Acute Kidney Injury through Pleiotropic Effects in Mice. Biomedicines 8(12):E572. 2020 Cancer studies General
Knorr DY, et al. (2020) Acetylcholinesterase promotes apoptosis in insect neurons. Apoptosis Aug 5 doi: 10.1007/s10495-020-01630-4. 2020 Neurobiology
Kocsmár É, et al. (2020) Cross-testing of major molecular markers indicates distinct pathways of tumorigenesis in gastric adenocarcinomas and synchronous gastrointestinal stromal tumors. Sci Rep 10(1):22212. 2020 Cancer studies Gastric cancer
Kong Q, et al. (2020) Identification of AflR Binding Sites in the Genome of Aspergillus Flavus by ChIP-Seq. J Fungi (Basel) 6(2):E52. 2020 Other
Kumar A, et al. (2020) Toll‐like receptor 2 (TLR2) engages endoplasmic reticulum stress sensor IRE1α to regulate retinal innate responses in Staphylococcus aureus endophthalmitis. FASEB J Aug 19 doi: 10.1096/fj.202001393R. 2020 Cell signaling
Kumari A, et al. (2020) Structural insights into actin filament recognition by commonly used cellular actin markers. EMBO J 39(14):e104006. 2020 Other
Lapitz A, et al. (2020) Patients With Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis. Cells 9(3):721. 2020 Disease study: Biomarker research
Lata E, et al. (2020) Thin-layer chromatographic quantification of magnolol and honokiol in dietary supplements and selected biological properties of these preparations. J Chromatogr A 1625: 461230. 2020 Other
Lee EH, et al. (2020) Knockdown of TRPM7 prevents tumor growth, migration, and invasion through the Src, Akt, and JNK pathway in bladder cancer. BMC Urol 20(1):145. 2020 Cell signaling
Lee J, et al. (2020) Androsamide, a Cyclic Tetrapeptide from a Marine Nocardiopsis sp., Suppresses Motility of Colorectal Cancer Cells. J Nat Prod Sep 28 doi: 10.1021/acs.jnatprod.0c00815. 2020 Cancer studies Colorectal cancer
Lee MH, et al. (2020) Licorice extract suppresses adipogenesis through regulation of mitotic clonal expansion and adenosine monophosphate‐activated protein kinase in 3T3‐L1 cells. 2020 Other
Lee R, et al. (2020) Effects of Gintonin-Enriched Fraction on Hippocampal Gene Expressions. Integr Med Res July 15 doi: 10.1016/j.imr.2020.100475. 2020 Method development
Lee SM, et al. (2020) FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging. Nat Commun 11(1):5661. 2020 Other
Li D, et al. (2020) Synergism of cisplatin-oleanolic acid co-loaded hybrid nanoparticles on gastric carcinoma cells for enhanced apoptosis and reversed multidrug resistance. Drug Deliv 27(1):191−199. 2020 Cancer Gastric
Li G, et al. (2020) Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome. Int J Mol Sci 21(7):2634. 2020 Other
Li J, et al. (2020) CircRNA TADA2A relieves idiopathic pulmonary fibrosis by inhibiting proliferation and activation of fibroblasts. 2020 Other
Li P, et al. (2020) LINC00271 inhibits epithelial-mesenchymal transition of papillary thyroid cancer cells by downregulating trefoil factor 3 expression. Aging Pathobiology and Therapeutics 2(2):78–85. 2020 Cancer studies General
Li Y, et al. (2020) microRNA-103a-3p confers protection against lipopolysaccharide-induced sepsis and consequent multiple organ dysfunction syndrome by targeting HMGB1. Infect Genet Evol Dec 14 doi: 10.1016/j.meegid.2020.104681 doi: 10.1016/j.meegid.2020.104681. 2020 Other
Liang L, et al. (2020) miR-4429 Regulates the Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Cervical Cancer by Targeting FOXM1. Cancer Manag Res 12:5301–5312. 2020 Cancer studies Cervical cancer
Lim D, et al. (2020) Targeted Delivery of the Mitochondrial Target Domain of Noxa to Tumor Tissue via Synthetic Secretion System in E. coli. Front Bioeng Biotechnol 2020 Drug mechanism
Lin YM, et al. (2020) Nerolidol improves cardiac function in spontaneously hypertensive rats by inhibiting Cardiac Inflammation and remodelling associated TLR4/NF-κB signaling cascade. Food Chem Toxicol Nov 17 doi: 10.1016/j.fct.2020.111837. 2020 Cell signaling
Linke V, et al. (2020) A large-scale genome–lipid association map guides lipid identification. Nat Metab Sep 21 doi: 10.1038/s42255-020-00278-3. 2020 Other
Liu EA, et al. (2020) Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain. JCI Insight Sep 15 doi: 10.1172/jci.insight.136676. 2020 Neurobiology
Liu R, et al. (2020) GPR120 Agonist GW9508 Ameliorated Cellular Senescence Induced by ox-LDL. ACS Omega 5:32195−32202. 2020 Cell signaling
Liu Y, et al. (2020) Ginsenoside Rh2 inhibits HeLa cell energy metabolism and induces apoptosis by upregulating voltage‑dependent anion channel 1. Int J Mol Med 46(5):1695–1706. 2020 Other
Lu CH, et al. (2020) Fic Proteins Inhibit the Activity of Topoisomerase IV by AMPylation in Diverse Bacteria. Front Microbiol August 26 doi: 10.3389/fmicb.2020.02084. 2020 Microorganisms and model organisms
Lu T, et al. (2020 Up-regulation of hypoxia-inducible factor antisense as a novel approach to treat ovarian cancer. Theranostics 10(15):6959–6976. 2020 Cancer studies Ovarian
Luo L, et al. (2020) Sestrin 2 Attenuates Sepsis-Associated Encephalopathy Through the Promotion of Autophagy in Hippocampal Neurons. J Cell Mol Med doi:10.1111/jcmm.15313. 2020 Neurobiology
Ma B, et al. (2020) Differential Histone Distribution Patterns in Induced Asymmetrically Dividing Mouse Embryonic Stem Cells. Cell Rep 32(6):108003. 2020 Stem cells
Mariano Jr EB, et al. (2020) Relationship of Fibronectic 1 (FN1) to the Extended Semen Shelf Life of Duson and Phillipine Native Boar-quezon at Different Storage Temperatures. Philipp J Vet Anim Sci 46(1):12–19. 2020 Other
Marín-Ramos NI, et al. (2020) MiR-18a inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations. Circ Res Aug 5 doi: 10.1161/CIRCRESAHA.119.316317. 2020 Neurobiology
Martin-Perez M, et al. (2020) PKC downregulation upon rapamycin treatment attenuates mitochondrial disease. Nat Metab 2(12):1472-1481 2020 Mitochondrial studies
McClellan EB, et al. (2020) L‐citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs. Pediatr Pulmonol Jul 14 doi: 10.1002/ppul.24960. 2020 Cell signaling
Merlo, S, et al. (2020) SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence. Biomolecules 10(3):364. 2020 Cell signaling
Miteva K, et al. (2020) Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression. Sci Rep 10(1):5791. 2020 Other
Morel G, et al. (2020) Mandibular‐Pelvic‐Patellar syndrome (MPP) is a novel PITX1‐related disorder due to alteration of PITX1 transactivation ability. Hum Mutat Jun 29 doi: 10.1002/humu.24070. 2020 Other
Móricz AM, et al. (2020) Bioactive clerodane diterpenes of giant goldenrod (Solidago gigantea Ait.) root extract. J Chromatogr A Nov 19 doi: 10.1016/j.chroma.2020.461727. 2020 Plant sciences
Móricz ÁM, et al. (2020) High-performance thin-layer chromatography hyphenated to high-performance liquid chromatography-diode array detection-mass spectrometry for characterization of coeluting isomers. Talanta 219: 121306. 2020 Method development
Morotti A, et al. (2020) The oncosuppressors MEN1 and CDC73 are involved in lncRNAs deregulation in human parathyroid tumors. J Bone Miner Res Aug 11 doi: 10.1002/jbmr.4154.  2020 Cancer studies General
Mu J, et al. (2020) Effect of Lactobacillus plantarum KFY02 isolated from naturally fermented yogurt on the weight loss in mice with high-fat diet-induced obesity via PPAR-α/γ signaling pathway. J Funct Foods 75 104264. 2020 Cell signaling
Mu J, et al. (2020) Lactobacillus fermentum CQPC06 in Naturally Fermented Pickles Prevents Non-alcoholic Fatty Liver Disease by Stabilizing the Gut-liver Axis in Mice. Food Funct Sep 18 doi: 10.1039/d0fo01823f. 2020 Microorganisms and model organisms
Nakamura-Bencomo s, et al. (2020) Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities. Invest New Drugs Oct 16 doi: 10.1007/s10637-020-01020-2.  2020 Cancer studies General
Neff AM, et al. (2020) Insulin Signaling Via Progesterone-Regulated Insulin Receptor Substrate 2 is Critical for Human Uterine Decidualization. Endocrinology 161:bqz021. 2020 Cell signaling
Nolte WW, et al. (2020) Screening trimethoprim primary metabolites for covalent binding to albumin. Med Chem Res 29:1238–1246. 2020 Other
Ogawa M, et al. (2020) Contribution of Extracellular O-GlcNAc to the Stability of Folded Epidermal Growth Factor-Like Domains and Notch1 Trafficking. Biochem Biophys Res Commun Mar 19 doi: 10.1016/j.bbrc.2020.03.066. 2020 Cell signaling
Othmène YB, et al. (2020) Oxidative stress, DNA damage and apoptosis induced by tebuconazole in kidney of male Wistar rats. Chem Biol Interact Jul 28 doi: 10.1016/j.cbi.2020.109114. 2020 Cell signaling
Othmène YB, et al. (2020) Tebuconazole induces ROS-dependent cardiac cell toxicity by activating DNA damage and mitochondrial apoptotic pathway. Ecotoxicol Environ Saf 204:111040. 2020 Cell signaling
Owiredu S, et al. (2020) In vitro Comparison of Hydroxocobalamin (B12a) and the Mitochondrial Directed therapy by a Succinate Prodrug in a Cellular Model of Cyanide Poisoning. Toxicol Rep 7:1263–1271. 2020 Mitochondrial studies
Özliseli E, et al. (2020) Rational evaluation of human serum albumin coated mesoporous silica nanoparticles for xenogenic-free stem cell therapies. Colloids Surf A Physico Chem Eng Asp 600:124945. 2020 Method development
Paldino E, et al. (2020) Modulation of Inflammasome and Pyroptosis by Olaparib, a PARP-1 Inhibitor, in the R6/2 Mouse Model of Huntington's Disease. Cells 9(10):E2286. 2020 Neurobiology
Paldino E, et al. (2020) Pyroptotic cell death in the R6/2 mouse model of Huntington's disease: new insight on the inflammasome. Cell Death Discov 6:69. 2020 Neurobiology
Pan H, et al. (2020) Lactobacillus plantarum KFY02 enhances the prevention of CCl4-induced liver injury by transforming geniposide into genipin to increase the antioxidant capacity of mice. J Funct Foods 73:104128. 2020 Microorganisms and model organisms
Pan H, et al. (2020) Mesenchymal Stem Cells Combined With Tissue Fusion Technology Promoted Wound Healing in Porcine Bowel Anastomosis. Stem Cells Int 2020:5142797. 2020 Stem cells
Pan H, et al. (2020) Mesenchymal Stem Cells Combined with Tissue Fusion Technology Promoted Wound Healing in Porcine Bowel Anastomosis. Stem Cells Int Feb 12 doi: 10.1155/2020/5142797. 2020 Other
Paradzik M, et al. (2020) KANK2 Links αVβ5 Focal Adhesions to Microtubules and Regulates Sensitivity to Microtubule Poisons and Cell Migration. Front Cell Dev Biol 8:125. 2020 Other
Park M, et al. (2020) Anti-FLT3 Nanoparticles for Acute Myeloid Leukemia: Preclinical Pharmacology and Pharmacokinetics. J Control Release 324:317-329. 2020 Cancer General
Pellavio G, et al. (2020) HPV Infection Affects Human Sperm Functionality by Inhibition of Aquaporin-8. Cells 9(5):E1241. 2020 Other
Pelletier J, et al. (2020) Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage. EMBO J 39(13):e103838. 2020 Other
Peng KC, et al. (2020) Expression of L-amino acid oxidase of Trichoderma harzianum in tobacco confers resistance to Sclerotinia sclerotiorum and Botrytis cinereal. Plant Sci Nov 24 doi: 10.1016/j.plantsci.2020.110772. 2020 Plant sciences
Pires Da Silva J, et al. (2020) SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy. Cells 9(2):426. 2020 Cell signaling
Plotnikov A, et al. (2020) PRMT1 inhibition induces differentiation of colon cancer cells. Sci Rep 10(1):20030. 2020 Cancer studies Colon cancer
Prieto-Garcia C, et al. (2020) Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells. MBO Mol Med 12(4):e11101. 2020 Cancer studies Squamous cell carcinoma
Protective effects of polymethoxyflavone-rich cold-pressed orange peel oil against ultraviolet B-induced photoaging on mouse skin. J Funct Foods 67:103834. 2020 Other
Qian B, et al. (2020) Ameliorative Effect of Sinapic Acid on Dextran Sodium Sulfate-(DSS-) Induced Ulcerative Colitis in Kunming (KM) Mice. Oxid Med Cell Longev 2020: 8393504. 2020 Other
Qu W, Li L. (2020) Loss of TREM2 confers resilience to synaptic and cognitive impairment in aged mice. J Neurosci Nov 2 doi: 10.1523/JNEUROSCI.2193-20.2020. 2020 Neurobiology
Raducanu V, et al. (2020) Simplified detection of polyhistidine-tagged proteins in gels and membranes using a UV-excitable dye and a multiple chelator head pair. J Biol Chem Jul 9 doi: 10.1074/jbc.RA120.014132.  2020 Method development
Raducanu VS, et al. (2020) Two Chromatographic Schemes for Protein Purification Involving the Biotin/Avidin Interaction Under Native Conditions. J Chromatography A Mar 17 doi: 10.1016/j.chroma.2020.461051. 2020 Method development
Reichermeier KM, et al. (2020) PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network. Mol Cell 77:1–15. 2020 Cell signaling
Roman B, et al. (2020) Nuclear-mitochondrial Communication Involving miR-181c Plays an Important Role in Cardiac Dysfunction During Obesity. J Mol Cell Cardiol 144:87−96. 2020 Mitochondrial studies
Sadiki A, et al. (2020) Site-specific Bioconjugation and Convergent Click Chemistry Enhances Antibody-Chromophore Conjugate Binding Efficiency. Photochem Photobiol Feb 21 doi: 10.1111/php.13231. 2020 Method development
Salgado-Lora MG, et al. (2020) Prolactin and Estradiol are Epigenetic Modulators in Bovine Mammary Epithelial Cells during Staphylococcus aureus Infection. Pathogens 9(7):E520. 2020 Other
Samanas NB, et al. (2020) Defective Nucleotide-Dependent Assembly and Membrane Fusion in Mfn2 CMT2A Variants Improved by Bax. Life Sci Alliance 3(5):e201900527. 2020 Mitochondrial studies
Sciamanna G, et al. (2020) Optogenetic Activation of Striatopallidal Neurons Reveals Altered HCN Gating in DYT1 Dystonia. Cell Rep 31(7):107644. 2020 Neurobiology
Seltzer J, et al. (2020) Interleukin-1 Receptor Associated Kinase (IRAK) Signaling in Kaposi Sarcoma-associated Herpesvirus (KSHV) Induced Primary Effusion Lymphoma. J Virol. JVI.02123-19. 2020 Cancer Karposi sarcoma
SH Siddiqui SH, et al. (2020) Direct exposure to mild heat stress stimulates cell viability and heat shock protein expression in primary cultured broiler fibroblasts. Cell Stress Chaperones Jul 22 doi: 10.1007/s12192-020-01140-x. 2020 General
Shahrouzi P, et al. (2020) Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis. Cancers (Basel) 12(9):E2593. 2020 Cancer studies: General
Shanmugapriya K, et al. (2020) Cellulose nanocrystals/nanofibrils loaded astaxanthin nanoemulsion for the induction of apoptosis via ROS-dependent mitochondrial dysfunction in cancer cells under photobiomodulation. Int J Biol Macromol 149:165−177. 2020 Cancer Skin
Shanmugapriya K, et al. (2020) Epidermal Growth Factor Receptor Conjugated Fucoidan/Alginates Loaded Hydrogel for Activating EGFR/AKT Signaling Pathways in Colon Cancer Cells During Targeted Photodynamic Therapy. Int J Biol Macromol May 6 doi: 10.1016/j.ijbiomac.2020.05.008. 2020 Cancer Colorectal
Shanmugapriya K, et al. (2020) Fucoidan-loaded hydrogels facilitates wound healing using photodynamic therapy by in vitro and in vivo evaluation. Carbohydr Polym 247:116624. 2020 Drug mechanism
Shi H, et al. (2020) Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease. Acta Neuropathol Commun 8(1):202. 2020 Neurobiology
Shin CH, et al. (2020) Exosomal miRNA-19a and miRNA-614 Induced by Air Pollutants Promote Proinflammatory M1 Macrophage Polarization via Regulation of RORα Expression in Human Respiratory Mucosal Microenvironment. J Immunol Oct 28  doi: 10.4049/jimmunol.2000456.  2020 Other
Siddiqui SH, et al. (2020) Chronic heat stress regulates the relation between heat shock protein and immunity in broiler small intestine. Sci Rep 10(1):18872. 2020 Other
Siregar, AS, et al. (2020) Dipeptide YA is Responsible for the Positive Effect of Oyster Hydrolysates on Alcohol Metabolism in Single Ethanol Binge Rodent Models. Mar Drugs 18(10):E512. 2020 Other
Somayajulu M, et al. (2020) Airborne Particulates Affect Corneal Homeostasis and Immunity. Invest Ophthalmol Vis Sci 61(4):23. 2020 Other
Soncini D, et al. (2020) Amino acid depletion triggered by ʟ-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death. Blood Adv 4(18):4312–4326 2020 Mitochondrial studies
Srivastava T, et al. (2020) Upregulated proteoglycan-related signaling pathways in fluid flow shear stress-treated podocytes. Am J Physiol Renal Physiol Jul 6 doi: 10.1152/ajprenal.00183.2020. 2020 Other
Stieg DC, et al. (2020) The extent of cyclin C promoter occupancy directs changes in stress-dependent transcription. J Biol Chem Sep 15 doi: 10.1074/jbc.RA120.015215.  2020 Other
Sun G, et al. (2020) Phoenixin-20 suppresses lipopolysaccharide-induced inflammation in dental pulp cells. Chem Biol Interact 318:108971. 2020 Cell signaling
Sun Y, et al. (2020) Therapeutic effect and mechanisms of the novel monosulfactam 0073. Antimicrob Agents Chemother Jul 27 doi: 10.1128/AAC.00529-20. 2020 Microorganisms and model organisms
Tayebi M, et al. (2020) Exosome Purification and Analysis Using a Facile Microfluidic Hydrodynamic Trapping Device. Anal Chem Jul 17 doi: 10.1021/acs.analchem.0c02006. 2020 Method development
Teng Y, et al. (2020) Lactobacillus plantarumLP104 ameliorates hyperlipidemia induced by AMPK pathways in C57BL/6N mice fed high-fat diet. J Functional Foods 64:103665. 2020 Microorganisms and model organisms
Thibeault PE, et al. (2020) Role of the Helix-8 and C-Terminal Tail in Regulating Proteinase Activated Receptor 2 Signaling. ACS Pharmacol Transl Sci Aug 10 doi:10.1021/acsptsci.0c00039. 2020 Cell signaling
Thongnak L, et al. (2020) Mitigation of renal inflammation and endoplasmic reticulum stress by vildagliptin and statins in high-fat high-fructose diet-induced insulin resistance and renal injury in rats. Biochim Biophys Acta Mol Cell Biol Lipids 1865(9):158755. 2020 Other
Tu MM, et la. (2020) Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy. Commun Biol 3(1):720. 2020 Cancer studies General
Vargas AM, et al. (2020) Methamphetamine Alters the TLR4 Signaling Pathway, NF-κB Activation, and Pro-Inflammatory Cytokine Production in LPS-challenged NR-9460 Microglia-Like Cells. Mol Immunol 121:159−166. 2020 Cell signaling
Verma DK, et al. (2020) The SUMO conjugase Ubc9 protects Dopaminergic cells from cytotoxicity and enhances the stability of α-synuclein in Parkinson's disease models. 2020 Neurobiology
Wang H, et al. (2020) DPP-4 Inhibitor Linagliptin Ameliorates Oxidized LDL-Induced THP-1 Macrophage Foam Cell Formation and Inflammation. Drug Des Devel Ther 2020(14):3929–3940. 2020 Other
Wang H, et al. (2020) Long non-coding RNA LICPAR regulates atrial fibrosis via TGF-β/Smad pathway in atrial fibrillation. Tissue Cell 67:101440. 2020 Cell signaling
Wang Y, et al. (2020) Pediococcus pentosaceus PP04 Ameliorates High-Fat Diet-Induced Hyperlipidemia by Regulating Lipid Metabolism in C57BL/6N Mice. J Agric Food Chem Dec 10 doi: 10.1021/acs.jafc.0c05060. 2020 Other
Wang Y, et al. (2020) Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway. Life Sci 259:118284 2020 Cell signaling
Wang Y, et al. (2020) TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition. Cell Death Dis 11(6):482. 2020 Stem cells
Wang Z, et al. (2020) Kaempferol Ameliorates Cisplatin Induced Nephrotoxicity by Modulating Oxidative Stress, Inflammation and Apoptosis via ERK and NF-κB Pathways. AMB Express 10(1):58. 2020 Cell signaling
Widyastuti HP, et al. (2020) Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis. BMC Med Genet 21(1):152. 2020 Disease study: Biomarker research
Widyastuti HP, et al. (2020) Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis. BMC Med Genet 21(1):152. 2020 Disease study: Biomarker research
Wössner N, et al. (2020) Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD + Dependent Lysine Deacetylases. Front Oncol 10:657. 2020 Cancer General
Wu A, et al. (2020) DNMT1 Promotes Cell Proliferation via Methylating hMLH1 and hMSH2 Promoters in EGFR-mutated Non-Small Cell Lung Cancer. J Biochem Mar 25 doi: 10.1093/jb/mvaa034. 2020 Cancer Lung
Wu C, et al. (2020) Evaluation of the Post-Treatment Anti-Inflammatory Capacity of Osteoarthritic Chondrocytes: An in vitro Study Using Baicalein. Regen Ther14:177−183. 2020 Cell signaling
Xiao P, et al. (2020) LncRNA NEAT1 regulates chondrocyte proliferation and apoptosis via targeting miR-543/PLA2G4A axis. 2020 Other
Xin L, et al. (2020) Methionine represses the autophagy of gastric cancer stem cells via promoting the methylation and phosphorylation of RAB37. Cell Cycle Sep 14 doi: 10.1080/15384101.2020.1814044. 2020 Cancer studies: Gastric cancer
Xin S, Ye L. (2020) Knockdown of long non‑coding RNA CCAT2 suppresses the progression of thyroid cancer by inhibiting the Wnt/β‑catenin pathway. Int J Mol Med Sept 4 doi: 10.3892/ijmm.2020.4761. 2020 Cancer studies General
Xin X, et al. (2020) Redox-responsive nanoplatform for codelivery of miR-519c and gemcitabine for pancreatic cancer therapy. Sci Adv 6(46):eabd6764. 2020 Cancer studies Pancreatic cancer
Xu WF, et al. (2020) Gasdermin E-derived caspase-3 Inhibitors Effectively Protect Mice From Acute Hepatic Failure. Acta Pharmacol Sin May 26 doi: 10.1038/s41401-020-0434-2. 2020 Drug mechanism
Xue W, et al. (2020) Rotenone Restrains the Proliferation, Motility and Epithelial-Mesenchymal Transition of Colon Cancer Cells and the Tumourigenesis in Nude Mice via PI3K/AKT Pathway. Clin Exp Pharmacol Physiol Apr 13 doi: 10.1111/1440-1681.13320. 2020 Cancer Colorectal
Yang M, et al. (2020) Preventive effect of lemon seed flavonoids on carbon tetrachloride-induced liver injury in mice. RSC Adv 10:12800−128009. 2020 Other
Yang X, et al. (2020) Inhibition of ITGB1 enhance the anti-tumor effect of cetuximab in colorectal cancer cell. Medicine (Baltimore) 99(27):e20944. 2020 Cancer studies Colorectal cancer
Yang Y, et al. (2020) Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents. Molecules 25(3):645. 2020 Cancer General
Yao Q, et al. (2020) Unsaturated fatty acid-enriched extract from Hippophae rhamnoides seed reduces skin dryness through up-regulating aquaporins 3 and hyaluronan synthetases 2 expressions. J Cosmet Dermatol Jul 8 doi: 10.1111/jocd.13482 2020 Other
Yee YH, et al. (2020) Sustained IKKβ Phosphorylation and NF-κB Activation by Superoxide-induced Peroxynitrite-mediated Nitrotyrosine Modification of B56γ3 and PP2A Inactivation. Redox Biol Dec 8 doi: 10.1016/j.redox.2020.101834. 2020 Cell signaling
Yi R, et al. (2020) Intervention effects of lotus leaf flavonoids on gastric mucosal lesions in mice infected with Helicobacter pylori. RSC Adv 10:23510. 2020 Plant sciences
Yoon JJ, et al. (2020) Betulinic Acid Protects DOX-Triggered Cardiomyocyte Hypertrophy Response through the GATA-4/Calcineurin/NFAT Pathway. Molecules 26(1):E53. 2020 Cell signaling
Zamorano-Leon JJ, et al. (2020) Factor Xa Inhibition by Rivaroxaban Modified Mitochondrial-Associated Proteins in Human Abdominal Aortic Aneurysms. Ann Vasc Surg Mar 12 doi: 10.1016/j.avsg.2020.02.005. 2020 Other
Zanin S, et al. (2020) Intracellular protein kinase CK2 inhibition by ferulic acid-based trimodal nanodevice. Int J Biol Macromol 165(Pt A):701–712. 2020 Other
Zeng N, et al. (2020) LEFTY2/endometrial Bleeding-Associated Factor Up-Regulates Na+ Coupled Glucose Transporter SGLT1 Expression and Glycogen Accumulation in Endometrial Cancer Cells. PLoS One 15(4):e0230044. 2020 Cancer Endometrial
Zeng Y, et al. (2020) The GPR55 Antagonist CID16020046 Mitigates Advanced Glycation End Products (AGEs)- Induced Chondrocyte Activation. Chem Biol Interact 325:109088. 2020 Cell signaling
Zeng ZL, et al. (2020) Highly Expressed lncRNA FOXD3-AS1 Promotes Non-Small Cell Lung Cancer Progression via Regulating miR-127-3p/mediator Complex Subunit 28 Axis. Euro Rev Med Pharmacol Sci 24: 2525−2538. 2020 Cancer Lung
Zhang H, et al. (2020) Silencing TTTY15 mitigates hypoxia-induced mitochondrial energy metabolism dysfunction and cardiomyocytes apoptosis via TTTY15/let-7i-5p and TLR3/NF-κB pathways. 2020 Cell signaling
Zhang H, et al. (2020) Structural, physicochemical and functional properties of Semen Ziziphi Spinosae protein. RSC Adv 10:29555. 2020 Plant sciences
Zhang J, et al. (2020) Identifying Mutation Hotspots Reveals Pathogenetic Mechanisms of KCNQ2 Epileptic Encephalopathy. Sci Rep 10(1):4756. 2020 Neurobiology
Zhang W, et al. (2020) LncRNA DANCR regulates osteosarcoma migration and invasion by targeting miR-149/MSI2 axis. Eur Rev Med Pharmacol Sci 24(12):6551–6560. 2020 Cancer studies General
Zhao L, et al. (2020) Puerarin alleviates coronary heart disease via suppressing inflammation in a rat model. Gene 771:145354. 2020 Cell signaling
Zhao Q, et al. (2020) Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output. Cell Sep 5 doi: 10.1016/j.cell.2020.08.009.  2020 Mitochondrial studies
Zhao T, et al. (2020) PD‑L1 expression increased by IFN‑γ via JAK2‑STAT1 signaling and predicts a poor survival in colorectal cancer. Oncol Lett May 20 doi.org/10.3892/ol.2020.11647. 2020 Cancer Colorectal
Zimmer A, et al. (2020) The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity. Eur J Pharmacol Nov 5 doi: 10.1016/j.ejphar.2020.173699.  2020 Other
Arreal L, et al. (2019) Targeting PML in triple negative breast cancer elicits growth suppression and senescence. Cell Death Differ Oct 1 doi: 10.1038/s41418-019-0407-5. 2019 Cancer Breast
Bellot GL, et al. (2019) MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management. Redox Biol 20:307−320. 2019 Drug mechanism
Bhatt T, et al. (2019) Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8. Cell Rep 29(9):2546−2555.e4. 2019 Cell signaling
Bloomfield M, Louie MC (2019) Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα. Sci Rep 9(1):12135. 2019 Cancer Breast
Chi X, et al. (2019) A system for site-specific integration of transgenes in mammalian cells. PLoS One 14(7):e0219842. 2019 Method development
Courtney AH, et al.(2019) CD45 functions as a signaling gatekeeper in T cells. Sci Signal Oct 22 doi: 10.1126/scisignal.aaw8151. 2019 Cell signaling
Depledge DP, et al. (2019) Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen. Nat Commun 10(1):754. 2019 Other
Dong Q, et al. (2019) A signal-flexible gene diagnostic strategy coupling loop-mediated isothermal amplification with hybridization chain reaction. Anal Chim Acta 1079:171−179. 2019 Method development
Durante L, et al. (2019) Characterization of the GPR1/FUN34/YaaH protein family in the green microalga Chlamydomonas suggests their role as intracellular membrane acetate channels. Plant Direct 3(6):e00148. 2019 Plant sciences
Englehart EA, Hoppins S. (2019) A catalytic domain variant of Mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion. J Biol Chem April 1 doi: 10.1074/jbc.RA118.006347. 2019 Mitochondrial studies
Funabara D, et al. (2019) Phosphorylation Properties of the N-Terminal Region of Twitchin from Molluscan Catch Muscle. American Journal of Molecular Biology 9:110−120. 2019 Cell signaling
Gansukh E, et al. (2019) Chemopreventive Effect of β-Cryptoxanthin on Human Cervical Carcinoma (HeLa) Cells Is Modulated through Oxidative Stress-Induced Apoptosis. Antioxidants (Basel) 9(1):28. 2019 Drug mechanism
Gao M, et al. (2019) Identification of a Cry1Fa binding site of cadherin in Plutella xylostella through fragment exchanging and molecular docking methods. Int J Biol Macromol 146:62−69. 2019 Method development
Groveman BR, et al. (2019) Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids. Acta Neuropathol Commun 7(1):90. 2019 Neurobiology
Hohl A, et al. (2019) Engineering a Polyspecific Pyrrolysyl-tRNA Synthetase by a High Throughput FACS Screen. Sci Rep 9(1):11971. 2019 Method development
Honda JR, et al. (2019) Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37. Am J Respir Cell Mol Biol Sep 23 doi: 10.1165/rcmb.2018-0278OC. 2019 Microorganisms and model organisms
Huang M, et al. (2019) HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway. Neurotox Res Dec 20 doi: 10.1007/s12640-019-00148-1. 2019 Neurobiology
Huang TL, et al. (2019) The therapeutic effect of aucubin-supplemented hyaluronic acid on interleukin-1 beta-stimulated human articular chondrocytes. Phytomedicine 53:1−8. 2019 Other
Jia QL, et al. (2019) Fisetin, via CKIP-1/REGγ, limits oxidized LDL-induced lipid accumulation and senescence in RAW264.7 macrophage-derived foam cells. Eur J Pharmacol Oct 23 doi: 10.1016/j.ejphar.2019.172748. 2019 Other
Kang D, et al. (2019) Heat Treatment at an Early Age Has Effects on the Resistance to Chronic Heat Stress on Broilers. Animals (Basel) 9(12):1022. 2019 Other
Kang JY, et al. (2019) 4,5-dicaffeyolquinic acid improves high-fat diet-induced cognitive dysfunction through the regulation of insulin degrading enzyme. J Food Biochem 43(7):e12855. 2019 Neurobiology
Karaszi K, et al. (2019) Increased placental expression of placental protein 5 (PP5) / tissue factor pathway inhibitor-2 (TFPI-2) in women with preeclampsia and HELLP syndrome: Relevance to impaired trophoblast invasion? Placenta 76:30−39. 2019 Disease study: Biomarker research
Kim DI, et al. (2019) Comparison of asthma phenotypes in OVA-induced mice challenged via inhaled and intranasal routes. BMC Pulm Med 19(1):241. 2019 Other
Lee BR, et al. (2019) Distinct role of Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) in inhibiting cargo-loading and release of extracellular vesicles. Sci Rep 9(1):20049. 2019 Cell signaling
Lee JY, et al. (2019) Red Blood Cell Membrane Bioengineered Zr-89 Labelled Hollow Mesoporous Silica Nanosphere for Overcoming Phagocytosis. Sci Rep 9(1):7419. 2019 Cancer General
Liu B, et al. (2019) Effects of Lactobacillus plantarum CQPC01-fermented soybean milk on activated carbon-induced constipation through its antioxidant activity in mice. Food Sci Nutr 7(6):2068−2082. 2019 Microorganisms and model organisms
Liu L, et al. (2019) Multiple BACE1 inhibitors abnormally increase the BACE1 protein level in neurons by prolonging its half-life. Alzheimers Dement (9):1183−1194. 2019 Neurobiology
Moricz AM, et al. (2019) Distinction and valorization of 30 root extracts of five goldenrod (Solidago) species. J Chromatography A Oct 7 doi: 10.1016/j.chroma.2019.460602. 2019 Plant sciences
Napso T, et al. (2019) Advanced maternal age compromises fetal growth and induces sex-specific changes in placental phenotype in rats. Sci Rep 9:16916. 2019 Other
O'Brien CE, et al. (2019) Hypoxia-Ischemia and Hypothermia Independently and Interactively Affect Neuronal Pathology in Neonatal Piglets with Short-Term Recovery. Dev Neurosci 41(1-2):17−33. 2019 Neurobiology
Oh TJ, et al. (2019) TBX3 represses TBX2 under the control of the PRC2 complex in skeletal muscle and rhabdomyosarcoma. Oncogenesis April 12 doi: 10.1038/s41389-019-0137-z. 2019 Cancer General
Oliveira-Mateos C, et al. (2019) The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition. Nat Commun 10(1):3979. 2019 Cancer General
Orlomoski R, et al. (2019) Rapid and efficient purification of Drosophila homeodomain transcription factors for biophysical characterization. Protein Expr Purif 158:9−14. 2019 Method development
Park C, et al. (2019) Species-specific inhibition of antiviral protein kinase R by capripoxviruses and vaccinia virus. Ann NY Acad Sci 1438(1):18−29. 2019 Microorganisms and model organisms
Park SK, et al. (2019) Fucoidan-Rich Substances from Ecklonia cava Improve Trimethyltin-Induced Cognitive Dysfunction via Down-Regulation of Amyloid β Production/Tau Hyperphosphorylation. Mar Drugs 17(10). 2019 Neurobiology
Qiang C, et al. (2019) Flavonoids from Apios americana Medikus Leaves Protect RAW264.7 Cells against Inflammation via Inhibition of MAPKs, Akt-mTOR Pathways, and Nfr2 Activation. Oxid Med Cell Longev 2019:1563024. 2019 Cell signaling
Qiao W, et al. (2019) A Novel Effect of Lipids Extracted from Vernix Caseosa on Regulation of Filaggrin Expression in Human Epidermal Keratinocytes. Ann Dermatol 31(6):611−620. 2019 Other
Rageul J, et al. (2019) Conditional degradation of SDE2 by the Arg/N-End rule pathway regulates stress response at replication forks. Nucleic Acids Res Jan 30 ePub:gkz054 2019 Other
Schultz ML, et al. (2019) Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann-Pick diseases. BMC Med 17(1):200. 2019 Neurobiology
Senthilkumar R, et al. (2019) Synthesis and Evaluation of Anisomelic acid-like Compounds for the Treatment of HPV-Mediated Carcinomas. Sci Rep 9(1):20295. 2019 Drug mechanism
Shi CS, et al. (2019) ARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes. Cell Death Discov 5:101. 2019 Cell signaling
Subramaniyan SA, et al.(2019) Effect of In Ovo Injection of L-Arginine in Different Chicken Embryonic Development Stages on Post-Hatchability, Immune Response, and Myo-D and Myogenin Proteins. Animals (Basel) Jun 14 doi: 10.3390/ani9060357. 2019 Other
Suzuki H, et al. (2019) Generation of bicistronic reporter knockin mice for visualizing germ layers. Exp Anim 68(4):499−509. 2019 Method development
Tas I, et al. (2019) Inflammatory and tumorigenic effects of environmental pollutants found in particulate matter on lung epithelial cells. Toxicol In Vitro 59:300−311. 2019 Cancer Lung
Thomson BR, et al. (2019) Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma. Elife Oct 17 doi: 10.7554/eLife.48474. 2019 Other
Tsai YH, et al. (2019) Effect of hesperidin on anti-inflammation and cellular antioxidant capacity in hydrogen peroxide-stimulated human articular chondrocytes. Process Biochemistry 85:175−184. 2019 Other
Upadhyay K, et al. (2019) Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function. Redox Biol 28:10131. 2019 Mitochondrial studies
Wang H, et al. (2019) High expression of the transcriptional coactivator TAZ is associated with a worse prognosis and affects cell proliferation in patients with medulloblastoma. Oncol Lett 18(5):5591−5599. 2019 Cancer Brain
Wang P, et al. (2019) Haspin inhibition delays cell cycle progression through interphase in cancer cells. J Cell Physiol Oct 17 doi: 10.1002/jcp.29328. 2019 Cancer General
Xing M, et al. (2019) Overexpression of p62/IMP2 can Promote Cell Migration in Hepatocellular Carcinoma via Activation of the Wnt/β-Catenin Pathway. Cancers (Basel) 12(1):7. 2019 Cancer Liver
Xuan F, et al. (2019) Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone. Arthritis Res Ther 21:241. 2019 Cell signaling
Yi R, et al. (2019) Lactobacillus plantarum CQPC02-Fermented Soybean Milk Improves Loperamide-Induced Constipation in Mice. J Med Food Oct 17 doi: 10.1089/jmf.2019.4467. 2019 Microorganisms and model organisms
Zamboni C, et al. (2019) Cyclin D1 immunohistochemical expression and somatic mutations in canine oral melanoma. Vet Comp Oncol Sep 10 doi: 10.1111/vco.12539. 2019 Cancer Skin
Zamorano-León JJ, et al. (2019) Effect of Pectin on the Expression of Proteins Associated with Mitochondrial Biogenesis and Cell Senescence in HT29-Human Colorectal Adenocarcinoma Cells. Prev Nutr Food Sci 24(2):187−196. 2019 Cancer Colorectal
Zhang J, et al. (2019) Expression and function of Toll like receptors in peripheral blood mononuclear cells in patients with ankylosing spondylitis. Mol Med Rep 20(4):3565−3572. 2019 Other
Zhao K, et al. (2019) TesG Is a type I secretion effector of Pseudomonas aeruginosa that suppresses the host immune response during chronic infection. Nat Microbiol 4(3):459−469. 2019 Microorganisms and model organisms
Zhao X, et al. (2019) Preventive effect of Lactobacillus plantarum KSFY02 isolated from naturally fermented yogurt from Xinjiang, China, on d-galactose-induced oxidative aging in mice. J Dairy Sci 102(7):5899−5912. 2019 Microorganisms and model organisms
Ha JS, et al. (2018) Anti-amyloidogenic properties of an ethyl acetate fraction from Actinidia arguta in Aβ1–42-induced ICR mice. Food Funct 9(6):3264−3277. 2018 Neurobiology
Hirpara J, et al. (2018) Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance. Redox Biol Dec 17 ePub:101076. 2018 Cancer General
Kelly SC, et al. (2018) Glucose-dependent trans-plasma membrane electron transport and p70S6k phosphorylation in skeletal muscle cells. Redox Biol Dec 12 ePub:101075. 2018 Cell signaling
Kim JM, et al. (2018) Ethyl acetate fraction from persimmon (Diospyros kaki) ameliorates cerebral neuronal loss and cognitive deficit via the JNK/Akt pathway in TMT-induced mice. Int J Mol Sci 19:E1499. 2018 Neurobiology
Li J, et al. (2018) Downregulation of Survivin gene expression affects Ionizing radiation resistance of human T98 glioma cells. Cell Mol Neurobiol 38:861–868 2018 Cancer Brain
Li J, et al. (2018) MicroRNA 423 promotes proliferation, migration and invasion and induces chemoresistance of endometrial cancer cells. Exp Ther Med 16(5):4213−4224. 2018 Cancer Endometrial
Lin SR, Wen CF (2018) PG-priming enhances doxorubicin influx to trigger necrotic and autophagic cell death in oral squamous cell carcinoma. J Clin Med 7(10):e375. 2018 Cancer Squamous cell carcinoma
Mishra R, et al. (2018) Can-miRn37a mediated suppression of ethylene response factors enhances the resistance of chilli against anthracnose pathogen Colletotrichum truncatum L. Plant Sci 267:135–147. 2018 Plant sciences
Park, SB, et al. (2018) Aruncus dioicus var. kamtschaticus extract suppresses mitochondrial apoptosis induced-neurodegeneration in trimethyltin injected ICR mice. J Food Biochem 42(6):e12667. 2018 Neurobiology
Qian Y, et al. (2018) Lactobacillus plantarum CQPC11 isolated from sichuan pickled cabbages antagonizes d-galactose-induced oxidation and aging in mice. Molecules 23(11):e3026. 2018 Other
Ran L, et al. (2018) Humoral factors contributing to ectopic bone formation induced by medical biomaterials. J Biomater Tissue Eng 8:880–886. 2018 Other
Schultz ML, et al. (2018) Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD. Nat Commun 9(1):3671. 2018 Neurobiology
Sun Y, et al. (2018) BMAL1 and CLOCK proteins in regulating UVB‐induced apoptosis and DNA damage responses in human keratinocytes. J Cell Physiol 233(12):9563−9574. 2018 Cell signaling
Taş I, et al. (2018) Physciosporin suppresses the proliferation, motility and tumourigenesis of colorectal cancer cells. Phytomedicine 56:10−20. 2018 Cancer Colorectal
Thawani A, et al. (2018) XMAP215 Is a microtubule nucleation factor that functions synergistically with the y-tubulin ring complex. Nat Cell Biol 20(5):575−585 2018 Structural biology/Protein interactions
Zhang G, et al. (2018) Detection of MiR-29a in plasma patients with lumbar spinal stenosis and the clinical significance. Mol Med Rep 18(1):223−229. 2018 Disease study: Biomarker research
Shen P, Chen J, Pan M. (2017) The protective effects of total paeony clycoside on ischemia/reperfusion injury in H9C2 cells via inhibition of the PI3K/Akt signaling pathway. Mol Med Rep 18:3332–3340. 2017 Cell signaling
">