BioPharma Finder Software Support

Documents

BioPharma Finder 4.0 QF1 Installation Instructions (Revision B)
BioPharma Finder User Guide - Software Version 4.0 (Revision A)
Search our database for Product Documents: Manuals, Product Literature

Resources

Applications Notebook: BioPharma Characterization Compendium – A Complete Toolbox of Techniques for Comprehensive Biopharmaceutical Characterization
Application Note: SMART Digest Compared to Classic In-Solution Digestion of Rituximab for In-Depth Peptide Mapping Characterization
Application Note: Robust and Reproducible Peptide Mapping and Intact Mass Analysis Workflows on a Single Instrument Platform
Application Note: Investigating Process-Related Post-Translational Modifications in NISTmAb RM 8671 Using High-Throughput Peptide Mapping Analysis
Application Note: Comparison of Alternative Approaches to Trypsin Protein Digestion for Reproducible and Efficient Peptide Mapping Analysis of Monoclonal Antibodies
Application Note: Subunit Analysis Approach for the Determination of Fucosylation Levels in Monoclonal Antibodies Using LC-HRAM-MS
Application Note: IdeS-Cleaved mAb Subunit Analysis with LC-HRAM-MS: A Quick and Accurate Comparison of Biosimilar and Originator Biotherapeutics
Application Note: Full Characterization of Heterogeneous Antibody Samples Under Denaturing and Native Conditions on the Q Exactive BioPharma Mass Spectrometer
Application Note: Quick Screening of Intact Antibody and Antibody-Drug Conjugates with Integrated Microfluidic Capillary Electrophoresis and Mass Spectrometry
Application Note: HILIC – An Alternative Separation Technique for Glycopeptides
Application Note: Complete Characterization of a Lysine-Linked Antibody Drug Conjugate by Native LC/MS Intact Mass Analysis and Peptide Mapping
Case Study: Characterizing Therapeutic Proteins for Drug Discovery and Development – A Therapeutic Protein Mass Spectrometry
Poster: Full Characterization and Confirmation of Diverse Oligonucleotides by Ion-Pairing Chromatography Coupled with the Q Exactive HF-X HRMS
Poster: Full Characterization and Confirmation of Diverse Oligonucleotides by Ion-Pairing Chromatography Coupled with the Q Exactive HF-X HRMS
Poster: Top Down Mass Spectrometry with Multiple MS/MS Strategies to Identify Age-Related Proteoform Changes in Tear Fluid
Poster: Optimized Workflow for Structure Elucidation of Pharmaceutically Relevant Extractables and Leachables
Poster: Middle-Down Analyses of Unmodified and Stressed Monoclonal Antibodies Using an Orbitrap Fusion Lumos Tribrid Mass Spectrometer
Poster: Improved Middle-Down Characterization of Antibodies Using Multiple Ion Activation Techniques and Ion-Ion Proton Transfer Reactions on a Modified Orbitrap Mass Spectrometer
Poster: Intact Mass Analysis of an 8-Arm Branched PEG-Protein Conjugate Using Native Liquid Chromatography and Ultra-High Mass Range Orbitrap MS
Poster: Assessing Biosimilarity by Monitoring Multiple Critical Quality Attributes of an Intact Monoclonal Antibody Drug Using Orbitrap Native LC-MS
Poster: Detection and Identification of New Features as Part of Mass Spectrometry-Based Quality Control
Poster: Evaluation of a Microfluidic Electrophoresis Device Coupled to an Orbitrap Mass Spectrometer for the Characterization of Biotherapeutics Proteins
Poster: Native Ion Exchange Chromatography Directly Coupled to Orbitrap Mass Spectrometry Allows Surface Charge Discrimination and Online Detection of Intact Proteins
Poster Note: Evaluation of Different Hydrogen/Deuterium Exchange Data Processing Software by Looking at Conformational Changes Induced by mAb Aggregation
NCBI Publication: Characterization of Site-Specific Glycosylation in Influenza A Virus Hemagglutinin Produced by Spodoptera frugiperda Insect Cell Line
NCBI Publication: Quantitative Top-Down Mass Spectrometry Identifies Proteoforms Differentially Released during Mechanical Stimulation of Mouse Skin

Training, Events, and Webinars

Installation/Upgrade

Protein Sequence Manager

Peptide Mapping Analysis

Intact Analysis

Top Down Analysis

Tools, Software, and Calculators

Thermo Fisher Cloud: A secure place to store, analyze, and share data
XCalibur™ Software: Control, and process data from, Thermo Scientific™ LC-MS systems
LCQUAN™ Quantitative Software: Acquire and manage quantitative LC-MS data in a 21 CFR Part 11 compliant environment
TraceFinder™ Software: Targeted and untargeted analysis made simple
Chromeleon™ 7.2 Chromatography Data System (CDS) Software: First CDS to unify the workflows for chromatography and routine quantitative mass spectrometry (MS) analysis

Explore our “Getting Started” and “How do I Tips” sections for solutions to top inquiries and common problems. Browse through our "Guides and Tools" section to access a comprehensive portfolio of product-related support resources.

Getting Started

"How do I" Tips

Guides and Tools

Installation/Upgrade

BioPharma Finder: Downloading the Demo Software

Protein Sequence Manager

BioPharma Finder: Protein Sequence Manager - Adding intact proteins

BioPharma Finder: Protein Sequence Manager - Adding modifications to a protein sequence

Peptide Mapping Analysis

BioPharma finder: Peptide Mapping Experiment

BioPharma Finder: Peptide Mapping Experiment - Custom Filter

BioPharma Finder: Peptide Mapping - Editing

BioPharma Finder: Peptide Mapping - Loading Results

BioPharma Finder: Peptide Mapping - Setting up Experiment

BioPharma Finder: Peptide Mapping - Stress Study Overview

BioPharma Finder: De Novo Sequencing

BioPharma Finder: Targeted analysis

BioPharma Finder: User Defined Coverage Map - Peptide Mapping Analysis

BioPharma Finder: User Defined Modification Summary - Peptide Mapping Analysis

Intact Analysis

BioPharma Finder: Intact Protein Analysis

BioPharma Finder: Kadcycla Native Intact Analysis

BioPharma Finder: Multiple File UVPD Dataset

BioPharma Finder: ADC Intact Deconvolution

BioPharma Finder: Intact Deconvolution

BioPharma Finder: Intact protein - copy and edit

BioPharma Finder: Intact protein - multiple chain analysis

BioPharma Finder: Native Intact Analysis

BioPharma Finder: Subunit Intact Analysis

Top Down Analysis

BioPharma Finder: Top Down Analysis

BioPharma Finder: Creating a protein sequence for Top Down Analysis