Reprogramming somatic cells to induced pluripotent stem cells is a critical and potentially time intensive step in your stem cell research. That’s why we offer choices in integration-free reprogramming technologies and services that fit your research and translational needs including our Cell Therapy Systems (CTS) Products, which are designed for clinical and translational research applications. We also provide services – you can do it yourself or let us do it for you.
Which reprogramming product or service is right for you?
| Order | Order | Order | Order | Inquire | |
| Episomal iPSC Reprogramming Vectors* | Epi5 Episomal iPSC Reprogramming Kit** | CytoTune-iPS 2.0 Sendai Reprogramming Kit | CTS CytoTune-iPS 2.1 Sendai Reprogramming Kit | Stem Cell Research Services - Reprogramming | |
|---|---|---|---|---|---|
| Description | Proven technology for viral-free iPSC generation | High-efficiency viral-free system requiring no small molecules | Highest efficiency integration-free reprogramming system | High-efficiency reprogramming system for clinical research | Pluripotent stem cells with your genetic background of interest and world-class support, delivered to you |
| Reprogramming Efficiency | 0.002–0.08% | 0.04–0.3% | 0.02–1.2% | 0.01–0.6% | 0.02–1.2% |
| Genes utilized | Thomson/ Yamanaka factors | Yamanaka factors +Lin28 | Yamanaka factors | Yamanaka factors Klf4, Oct4, Sox2 and L-myc | Yamanaka factors |
| Training and expertise required | Moderate | Moderate | Minimal | Minimal | None; experienced stem cell researchers generate the lines on your behalf |
| Genomic integration-free | ✓ | ✓ | ✓ | ✓ | ✓ |
| Virus-free reprogramming | ✓ | ✓ | ✓ | ||
| Blood cell reprogramming | ✓ | ✓ | ✓ | ✓ | ✓ |
| Transfection products | Neon Transfection System or similar device | Neon Transfection System or Lipofectamine 3000 | None | None | None |
| Reporter available | N/A | N/A | CytoTune-EmGFP Sendai Fluorescence Reporter | CytoTune-EmGFP Sendai Fluorescence Reporter | CytoTune-EmGFP Sendai Fluorescence Reporter |
*Commercialized in Partnership with Cellular Dynamics International.
**Designed by Dr. Okita in the laboratory of Professor Yamanaka at the Center for iPS Cell Research and Application (CiRA), Kyoto University.
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Advances in Stem Cell Research Cell Reprogramming with Episomal iPSC Reprogramming Vectors
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