Thermo Scientific dialysis devices are available in a variety of dialysis options for the rapid and trouble-free dialysis of sample volumes ranging from 10 μL–250 mL. Unlike traditional dialysis tubing, these innovative devices do not require knots or clips that can lead to leaks and sample loss.
Pierce 96-well Microdialysis Plates and Slide-A-Lyzer Dialysis MINI Devices are excellent for small volumes, Slide-A-Lyzer G3 Dialysis Cassettes are recommended for small to medium volumes, and Slide-A-Lyzer Dialysis Flasks are recommended for larger volumes.
- Excellent sample recoveries—low-binding plastic and membrane help minimize sample loss compared to filtration and resin systems
- Convenient—easy-to-grip format helps simplify sample addition and removal with syringe and/or pipette
- Secure—sealed membranes help prevent leakage that can occur with dialysis tubing and homemade devices
- Validated—each device is leak-tested during production
Advantages of Slide-A-Lyzer Dialysis Cassettes over traditional tubing
 |  | |
|---|---|---|
| Dialysis product | Traditional tubing | Cassette |
| Sample handling | Slippery when wet Flat tubing is difficult to handle when wet, increasing risk of sample loss during sample addition/removal | Easy handling and secure sample delivery Plastic frame and cap allow for secure sample addition/removal |
| Sample recovery | Risk of sample loss Sample can leak out if clamp becomes loose or falls off | Sample protection Welded membrane and leak-proof cap helps minimize the risk of sample loss |
| Speed | Time consuming Non-optimized design that typically requires overnight dialysis | Fast and efficient Innovative design with high surface/volume ratio allows for more rapid dialysis than conventional tubing |
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Choose the right dialysis device for your experiment
 |  | |  | |
|---|---|---|---|---|
| Pierce 96-well Microdialysis Plates | Slide-A-Lyzer MINI Dialysis Devices | Slide-A-Lyzer G3 Dialysis Cassettes | Slide-A-Lyzer Dialysis Flasks | |
| External float required? | No | No | No | Optional |
| Method of sample addition/removal | Pipette | Pipette | Pipette | Pipette |
| Volume range | 10–100 μL | 10 μL–2 mL | 3–125 mL | 150–250 mL |
| Number of devices with different volume capacities | 1 | 3 | 5 | 1 |
| Molecular weight cutoffs (MWCOs) | 3.5K, 10K | 2K (0.1 mL size only), 3.5K, 10K, 20K | 2K, 3.5K, 10K, 20K | 2K, 3.5K, 10K, 20K |
| Automation compatible? | Yes | No | No | No |
| Integrated buffer reservoir? | Yes | Yes, except 0.1 mL size | No | No |
| Gamma-irradiated options? | No | No | No (E-Beam irradiated available) | No |
| Molecular weight cutoff (MWCO) color coded? | No | Yes | Yes | Yes |
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