Single-use bioprocessing film: Quality and reliability you can trust
The cornerstone of single-use technologies is reliable film for your bioprocessing containers (BPCs). Thermo Scientific Aegis film is designed to support healthy cell growth and provide the ideal balance of strength and flexibility to help meet your upstream and downstream needs.
This paper details some of the important characteristics of films used to manufacture BPCs, with a discussion on E&L and Thermo Fisher Scientific’s strategy for characterizing the extractables profiles of our BPC films.
Bioprocessing film with superior reliability and bio-compatibility, backed by decades of experience
- Exceptional strength and leak resistance to minimize product loss—0.01% leak rate outperforms industry averages
- Demonstrated biocompatibility and low cytotoxicity to support healthy cell growth—free of Irgafos® 168 stabilizer, which has been shown to affect cell growth with certain cell clones
- Low leachable and extractable profiles to support end-product purity and quality—extensive extractable and leachable analysis performed, aligned with current BioPhorum Operations Group (BPOG) guidelines
- No PFAS—there are no PFAS, also known as forever chemicals, in Aegis films
Standardize across your workflow to help minimize risk and enable maximize efficiency
Gibco media and process liquids and buffers are packaged in the same high-quality film used for Thermo Scientific bioprocess bags and tubing assemblies.
First-of-its-kind film for Bioprocessing Containers (BPCs)
Our biobased films have a significantly lower carbon footprint
Reduce environmental impact without having to validate new BPCs
Versatile
Aegis film is a versatile film with applications across the workflow, from mixing and holding process liquids to media bags and housing the cell culture. Gibco media and supplements are available in bioprocessing containers made with Aegis film.
Efficient
Consistent film across the workflow allows you to save time with a simplified validation and qualification experience.
Scalable
This supports scale-up needs with bioprocessing container bags available from 50 mL to 5,000 L.
Supply assurance
Excellent lead times enabled by the largest single-use manufacturing network, with in-region manufacturing that flexes with market demand.
Expertise
Experience customer partnership and expertise across the workflow to support optimizing your process.
Thoughtfully designed physical properties for exceptional quality, purity, and biocompatibility
- Polyester—gas permeable layer provides wear and abrasion resistance and strength
- Tie—binds dissimilar layers together
- EVOH—gas barrier prevents oxygen from transmitting through the film and supports liquid stability
- PE—inert product contact layer with low extractables helps prevent liquid from being affected by the film
Aegis film is featured on the following products
Bioprocessing films that help meet your needs
We have spent decades optimizing our processes and have developed advanced manufacturing techniques that are purpose-designed, custom-built, and focused on process improvement.
Beyond Aegis, Thermo Fisher Scientific offers several additional films including CX5-14, ASI 26/77, and ASI 28.
Bioprocessing resources
Access a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing:
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For Research Use or Further Manufacturing. Not for diagnostic use or direct administration into humans or animals.