SSCP is an electrophoretic mobility assay used to find variants in a large number of samples so that fewer DNA sequencing runs are needed.
The development and progression of cancer is a complex process, and many nucleic acid modifications are believed to play significant roles. These include single mutations in the DNA, RNA or mitochondrial DNA, deletions, insertions, and duplications of a gene (or part of a gene), DNA methylation, alternative splicing events, and more. Applied Biosystems® genetic analyzers and associated kits offer the flexibility you need to get the answers you’re looking for.
Screening Prior to Sequencing
Learn more about:
Mutation Detection
DNA mutations are the most common events driving the development of cancer. Our kits and genetic analysis instruments help simplify your application development process—for example SNP detection (a single SNP or up to 10 SNPs located on different DNA segments) and sequencing complete genes.
Learn more about:
Genetic Rearrangement
Genetic rearrangements—including duplications, inversions, and deletions of DNA fragments—are known to contribute to many genetic diseases.
Learn more about:
Methylation Analysis
DNA methylation plays an important role in the regulation of gene expression and, consequently, in the appearance of various disease states. Using our methylation detection solutions, you can determine the overall level of methylation or identify the methylation status of a specific CpG.
Learn more about:
Visistat reference component
For Research Use Only. Not for use in diagnostic procedures.