Inducible to Give You Control
Many traditional cell lines are limited to transient or constitutive expression. The T-REx™ system allows tight control and yields high levels of induced expression.
Overview
The T-REx™ system is based on Tet-regulated expression. T-REx™ cell lines can be used to regulate expression of gene sequences, shRNAs, and miRNAs. The T-REx™ system uses a strong CMV promoter and does not rely on viral transactivators.
Invitrogen Custom Services can develop a host T-REx™ cell line expressing the Tet repressor and/or a T-REx™ expression cell line facilitating the induction of your gene of interest in your cell line of interest depending on your needs and budget.
Invitrogen Custom Services can develop a host T-REx™ cell line expressing the Tet repressor and/or a T-REx™ expression cell line facilitating the induction of your gene of interest in your cell line of interest depending on your needs and budget.
Development Options
- T-REx™ Host cell line - Let our services team establish and validate the expression of the tet repressor protein in your cell line of interest.
- T-REx™ Expression cell line - Let our services team establish and validate the inducible expression of your protein of interest from your TREx Host cell line of interest.
- Co-development of the Flp-In™ T-REx™-adapted cell lines
Frequently Asked Questions
Q. Is the T-REx™ system a Tet-on or Tet-off system?
A. Tet-on.
Q. Which applications are best for the T-REx™ system?
A. Studies involving toxic proteins, cell cycle–regulated expression, and RNAi, among others. Please call for more information.
A. Tet-on.
Q. Which applications are best for the T-REx™ system?
A. Studies involving toxic proteins, cell cycle–regulated expression, and RNAi, among others. Please call for more information.
For more information, email europeservices@lifetech.com
