Improve analytical consistency and reproducibility while saving time and money
No need to manually prepare eluent. Eluent generation (EG) cartridges electrolytically produce high-purity hydroxide, carbonate, and methanesulfonic acid eluents for isocratic and gradient runs in RFIC systems. Just add water.
Eluent generation cartridges
Automate generation of potassium, sodium and lithium hydroxide eluents. The potassium hydroxide cartridge is available in standard pressure (ECG III KOH), high pressure (EGC 500) and capillary high pressure (EGC-KOH capillary) formats. Potassium hydroxide eluent can be used with can be used with hydroxide-selective columns, such as Dionex IonPac AS19, AS18, AS15 capillary columns.
MSA cartridges are available in standard pressure (ECG III MSA), high pressure (EGC 500) and capillary high pressure (EGC-MSA capillary) formats. MSA eluent can be used with columns such as Dionex IonPac CS12A, CS16, CS18, and CS19 capillary columns.
Generate potassium carbonate eluent electrolytically. This cartridge is used with the Thermo Scientific Dionex Electrolytic pH Modifier for anion separations with carbonate eluent based columns. Carbonate eluent can be used with columns such as Dionex IonPac AS14A columns.
How RFIC-EG works
Systems with Reagent-Free IC Eluent Generation (RFIC-EG) automatically generate high-purity hydroxide, carbonate, bicarbonate or methanesulfonic acid (MSA) eluent electrolytically using Thermo Scientific Dionex EGC Eluent Generator Cartridges. All that’s needed on an RFIC-EG system is a high-purity source of deionized water.
The system will automatically generate eluent at the concentration you indicate, which can follow either an isocratic or gradient method. This means that gradient analyses can be accomplished using an isocratic pump. Eluent is purified on-line using the Thermo Scientific Dionex CR-TC Continuously Regenerated Trap Column, and suppressed electrolytically before detection, without the need to prepare regenerant.
RFIC-EG benefits
RFIC-EG delivers superior results by preventing baseline shift, increasing sensitivity, improving resolution, and ensuring consistent peak integration
- Improves analytical consistency and reproducibility, day-to-day, system-to-system, lab-to-lab
- Provides uniform, highly stable eluent concentrations
- Generates highly reproducible results, with little variability in peak retention times or areas
- Enables gradient separation with an isocratic pump
EGC-cartridge and system compatibility
Which Thermo Scientific Dionex EGC Eluent Generator Cartridges to Use | ||||
|---|---|---|---|---|
| Instrument | Anions | Cations | ||
| Gradient or Isocratic Hydroxide EG | Isocratic Carbonate EG | Isocratic Carbonate / Bicarbonate EG | Gradient or Isocratic MSA EG | |
| Dionex Inuvion with RFIC | Dionex EGC 500 KOH | Dionex EGC 500 K2CO3 | Dionex EGC 500 K2CO3 + EPM 500 | Dionex EGC 500 MSA |
| Dionex Integrion | Dionex EGC III KOH, NaOH+, LiOH+, and EGC 500 KOH | Dionex EGC 500 K2CO3 | Dionex EGC 500 K2CO3+ EPM 500 | Dionex EGC III MSA Cartridge, EGC 500 MSA |
| Dionex ICS-6000 | Dionex EGC III KOH, NaOH+, LiOH+, and EGC 500 KOH | Dionex EGC 500 K2CO3 | Dionex EGC 500 K2CO3+ EPM 500 | Dionex EGC III MSA Cartridge, EGC 500 MSA |
How RFIC-EG works
Systems with Reagent-Free IC Eluent Generation (RFIC-EG) automatically generate high-purity hydroxide, carbonate, bicarbonate or methanesulfonic acid (MSA) eluent electrolytically using Thermo Scientific Dionex EGC Eluent Generator Cartridges. All that’s needed on an RFIC-EG system is a high-purity source of deionized water.
The system will automatically generate eluent at the concentration you indicate, which can follow either an isocratic or gradient method. This means that gradient analyses can be accomplished using an isocratic pump. Eluent is purified on-line using the Thermo Scientific Dionex CR-TC Continuously Regenerated Trap Column, and suppressed electrolytically before detection, without the need to prepare regenerant.
RFIC-EG benefits
RFIC-EG delivers superior results by preventing baseline shift, increasing sensitivity, improving resolution, and ensuring consistent peak integration
- Improves analytical consistency and reproducibility, day-to-day, system-to-system, lab-to-lab
- Provides uniform, highly stable eluent concentrations
- Generates highly reproducible results, with little variability in peak retention times or areas
- Enables gradient separation with an isocratic pump
EGC-cartridge and system compatibility
Which Thermo Scientific Dionex EGC Eluent Generator Cartridges to Use | ||||
|---|---|---|---|---|
| Instrument | Anions | Cations | ||
| Gradient or Isocratic Hydroxide EG | Isocratic Carbonate EG | Isocratic Carbonate / Bicarbonate EG | Gradient or Isocratic MSA EG | |
| Dionex Inuvion with RFIC | Dionex EGC 500 KOH | Dionex EGC 500 K2CO3 | Dionex EGC 500 K2CO3 + EPM 500 | Dionex EGC 500 MSA |
| Dionex Integrion | Dionex EGC III KOH, NaOH+, LiOH+, and EGC 500 KOH | Dionex EGC 500 K2CO3 | Dionex EGC 500 K2CO3+ EPM 500 | Dionex EGC III MSA Cartridge, EGC 500 MSA |
| Dionex ICS-6000 | Dionex EGC III KOH, NaOH+, LiOH+, and EGC 500 KOH | Dionex EGC 500 K2CO3 | Dionex EGC 500 K2CO3+ EPM 500 | Dionex EGC III MSA Cartridge, EGC 500 MSA |
Automatically generate eluent gradients to analyze complex carbohydrates by operating your Thermo Scientific Dionex ICS-6000 HPIC system in Dual Eluent Generation Cartridge (Dual EGC) mode. This novel option uses a methanesulfonic acid (MSA) EGC cartridge and a potassium hydroxide (KOH) EGC cartridge in series with each other to generate the extremely reproducible and accurate KOH/KMSA eluent gradient needed for analyzing complex carbohydrates such as oligosaccharides.