Lentiviral vector manufacturing solutions
Lentiviral vectors are a widely used modality for gene modification in cell therapy manufacturing processes. The innovative lentivirus production solutions from Thermo Fisher Scientific are designed to accelerate and streamline the development of gene-modified cell therapies and gene therapies.
Lentiviral production workflow
Plasmid development and productionCentral to the lentiviral production workflow is large-scale plasmid production and purification. From DNA vector selection to large-scale production and purification platforms, we have solutions to meet your needs: |
Gene synthesis services
Lentiviral vector productionWe offer a scalable, HEK293-based suspension cell system optimized for large-scale lentiviral vector production. |
Lentiviral production systems
Bioprocessing liquids and cell culture media preparation
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Purification
To scale your research, we have developed chromatography resins for lentiviral vectors along with single-use solutions for robust vector processing.
Mixers, buffers and single-use solutions
Analytics and characterization development
To help ensure regulatory approval of the final lentiviral vector product, QC testing must be implemented. We offer rapid molecular methods for quantification, contaminant and impurity testing across the workflow.
- Mycoplasma detection
- Residual host cell DNA quantitation
- Residual plasmid DNA quantitation
- ViralSEQ Lentivirus quantitation
Fill and finish development
Once the final product has been purified, passed the necessary quality and release testing criteria for clinical use, it is ready for formulation, final fill and finish.
CRO and CDMO Services
Our cell and gene therapy CRO solutionssupport customers through the unique demands that cell and gene therapy clinical trials call for. The extensive breadth and depth of therapeutic and functional expertise have guided a diverse range of cell and gene therapy assets through the development pipeline
Our Viral Vector Contract Manufacturing Services support clients from drug development to full-scale manufacturing. In addition to product release, stability testing, process and analytical qualification, and custom cell line engineering, we provide global quality compliance and regulatory support.
Intended use of the products mentioned on this page vary. For specific intended use statements please refer to the product label.