Gibco PeproTech recombinant growth factors for cell culture
Growth factors are cell signaling proteins that play important roles in cell proliferation, differentiation, and survival. In cell culture, growth factors can be supplied as serum or purified recombinant proteins. High-quality cell culture growth factors support cell health and provide stable and repeatable conditions for in vitro studies of mammalian cells. By optimizing concentrations of growth factors in cell culture, you can drive proliferation or differentiation to a particular phenotype.
Recombinant growth factors provide consistent behavior of cell cultures
Use of recombinant growth factors in mammalian cell culture gives you a higher level of control over experimental conditions, which can lead to more reproducible results in cell-based studies. PeproTech growth factors are high-quality recombinant proteins that offer consistency in quality and supply, reducing the risk of failed cell cultures and lost time.
Most-used cell culture growth factors
EGFEpidermal growth factor EGF for cell culture of epithelial and fibroblast cells | FGF-2Basic fibroblast growth factor aka FGF basic, bFGF; for maintaining undifferentiated cells | BDNFBrain-derived neurotrophic factor Promotes neuronal survival and differentiation | VEGFVascular endothelial growth factor Induces endothelial cell proliferation and angiogenesis | GM-CSFGranulocyte macrophage colony-stimulating factor Hematopoietic cell modulating cytokine |
Benefits of using PeproTech growth factors
- Reproducible potency of growth factor performance in cell culture
- Consistent sourcing and performance throughout the RUO to GMP development process
- Confidence that your growth factors will perform time after time
Recombinant growth factor potency and quality
The purity of each PeproTech growth factor lot is at least 98% as determined by SDS-PAGE and/or HPLC. In addition, each lot is tested for functionality and potency in cell-based assays.
Lot-to-lot consistency of recombinant growth factors supports robust cell culture processes
Figure 1A. Proliferation assay of 3T3 cells to test activity of PeproTech human EGF. Potency is highly similar across lots.
Figure 1B. Proliferation assay of 3T3 cells to test activity of PeproTech human FGF-basic. Potency is highly similar across lots.
Consistency of cell culture materials aids the journey from lab to clinic
Figure 2A. Proliferation assay of 3T3 cells to test activity of PeproTech human EGF. Potency is highly similar between animal-free human EGF (RUO) and PeproGMP human EGF.
Figure 2B. Proliferation assay of 3T3 cells to test activity of PeproTech human FGF-basic. Potency is highly similar among RUO, animal-free, and GMP recombinant proteins.
Gibco and PeproTech heat-stable recombinant growth factors have been engineered for greater stability in cell culture conditions. Get exceptional performance and retain bioactivity without artificially high concentrations. |
PeproTech animal-free recombinant proteins are manufactured using raw materials that are not of animal origin. |
Thermo Fisher Scientific offers an extensive catalog of recombinant proteins for use in a variety of applications including functional assays, immunoassays, and analytic controls. Search and filter the collection by species, expression system, and product grade.
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Intended use of the products mentioned on this page vary. For specific intended use statements please refer to the product label.
For Research Use Only. Not for use in diagnostic procedures.