Aquilos 2 Cryo-FIB Resources

"Cryo-tomography really shines because it's one of the few techniques that allows us to not only look at the details of the individual parts but also all of them holistically together."

“So with the workflow that we have now fully established at ISTA, we can really address a multitude of questions going from cell biology to high resolution structural biology all within a native context.”

“We want to understand structure and function of cellular processes that are relevant for human health across scales. We can do this now here at Human Technopole.  We can go from following the activity of macromolecular complexes by light microscopy to investigating their molecular structures within cells by cryo-ET or in isolation at higher resolution by single particle analysis to X-ray crystallography. We can cover the complete range of resolution.”

“The thing I love the most about this work is that every cell is different. It’s a glimpse into this unseen world and it’s always fascinating.”