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Automated cryo-plasma-FIB for throughput and connectivity for the cryo-electron tomography workflow

Cryo-electron tomography (cryo-ET) provides unprecedented insights into the inner workings of cells, but clear, reliable results depend on high-quality cryo-lamella preparation. The Thermo Scientific Arctis Cryo-Plasma Focused Ion Beam (cryo-PFIB) is specifically designed for automated, high-throughput production of cryo-lamellae from vitrified cells. Its Autoloader system provides a unique, direct connection between cryo-FIB-SEM sample preparation and cryo-transmission electron microscopy (cryo-TEM) within the tomography workflow.

Arctis Cryo-Plasma FIB capabilities

High quality lamella preparation

The Arctis Cryo-Plasma-FIB automates high-throughput TEM lamellae production and features Autoloader connectivity for the cryo-electron tomography workflow.

Connectivity for the cryo-ET workflow

With the Autoloader system, the Arctis Cryo-PFIB offers robotic sample loading, automatic sample processing, and storage of up to twelve frozen specimens with direct connection to any Autoloader-equipped cryo-TEM.

Arctis Cryo-Plasma-FIB resource

Learn more from scientists who are using the Arctis Cryo-PFIB and take a closer look with on-demand webinars and videos.

Correlation to light microscopy

“On-board” integrated fluorescence light microscope (iFLM) allows the same area to be observed with light, ion, or electron beams.

Cryo-ET service and support

To ensure optimal system performance, we provide you access to a world-class network of field service experts, technical support, and workflow validation.

Explore cryo-electron tomography

The Thermo Scientific cryo-electron tomography (cryo-ET) workflow is a complete end-to-end workflow covering cell culture to flash freezing cells to final 3D visualization and analysis.

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