Product References
Targeting myocardial equilibrative nucleoside transporter ENT1 provides cardioprotection by enhancing myeloid Adora2b signaling.
JCI insight
Ruan W,Li J,Choi S,Ma X,Liang Y,Nair R,Yuan X,Mills TW,Eltzschig HK
11-5921-82 was used in Flow cytometry/Cell sorting to reveal a previously unrecognized role for myocyte-specific ENT1 in cardioprotection by enhancing myeloid-dependent Adora2b signaling during reperfusion.
Thu Jun 08 00:00:00 EDT 2023
Centrosome function is critical during terminal erythroid differentiation.
The EMBO journal
Tátrai P,Gergely F
11-5921-82 was used in flow cytometry to show that disruption of centrosome and spindle function initiates macrocytic anaemias due to nutritional deficiency or exposure to chemotherapy.
Mon Jul 18 00:00:00 EDT 2022
Cellular architecture of human brain metastases.
Cell
Gonzalez H,Mei W,Robles I,Hagerling C,Allen BM,Hauge Okholm TL,Nanjaraj A,Verbeek T,Kalavacherla S,van Gogh M,Georgiou S,Daras M,Phillips JJ,Spitzer MH,Roose JP,Werb Z
11-5921-82 was used in Flow cytometry/Cell sorting to present an integrative analysis of >100,000 malignant and non-malignant cells from 15 human parenchymal BrMs, generated by single-cell transcriptomics, mass cytometry, and complemented with mouse model- and in silico approaches.
Thu Feb 17 00:00:00 EST 2022
Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity.
PloS one
Deshycka R,Sudaryo V,Huang NJ,Xie Y,Smeding LY,Choi MK,Ploegh HL,Lodish HF,Pishesha N
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Fri Dec 24 00:00:00 EST 2021
GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization.
JCI insight
Kashgari G,Venkatesh S,Refuerzo S,Pham B,Bayat A,Klein RH,Ramos R,Ta AP,Plikus MV,Wang PH,Andersen B
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Life science alliance
Valkov N,Das A,Tucker NR,Li G,Salvador AM,Chaffin MD,Pereira De Oliveira Junior G,Kur I,Gokulnath P,Ziegler O,Yeri A,Lu S,Khamesra A,Xiao C,Rodosthenous R,Srinivasan S,Toxavidis V,Tigges J,Laurent LC,Momma S,Kitchen R,Ellinor P,Ghiran I,Das S
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Western Blot
Wed Dec 01 00:00:00 EST 2021
SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Life science alliance
Valkov N,Das A,Tucker NR,Li G,Salvador AM,Chaffin MD,Pereira De Oliveira Junior G,Kur I,Gokulnath P,Ziegler O,Yeri A,Lu S,Khamesra A,Xiao C,Rodosthenous R,Srinivasan S,Toxavidis V,Tigges J,Laurent LC,Momma S,Kitchen R,Ellinor P,Ghiran I,Das S
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Western Blot
Wed Dec 01 00:00:00 EST 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Tue Apr 20 00:00:00 EDT 2021
Encapsulation of murine hematopoietic stem and progenitor cells in a thiol-crosslinked maleimide-functionalized gelatin hydrogel.
Acta biomaterialia
Gilchrist AE,Serrano JF,Ngo MT,Hrnjak Z,Kim S,Harley BAC
11-5921-82 was used in flow cytometry to report inclusion of a peptide crosslinker that can be cleaved via the proteolytic action of Sortase A and show that Sortase A exposure does not degrade sensitive surface marker expression patterns.
Wed Sep 01 00:00:00 EDT 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
11-5921-82 was used in Flow Cytometry to determine the impact of vitamin D signaling on prostatic precancerous lesions.
Thu Jul 01 00:00:00 EDT 2021
Sex Matters: Physiological Abundance of Immuno-Regulatory CD71+ Erythroid Cells Impair Immunity in Females.
Frontiers in immunology
Mashhouri S,Koleva P,Huynh M,Okoye I,Shahbaz S,Elahi S
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Mon Dec 20 00:00:00 EST 2021
Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemia.
Stem cell research & therapy
Wang B,Wang Y,Chen H,Yao S,Lai X,Qiu Y,Cai J,Huang Y,Wei X,Guan Y,Wang T,Wang J,Xiang AP
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Mon Jan 18 00:00:00 EST 2021
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Science advances
Heino S,Fang S,Lähde M,Högström J,Nassiri S,Campbell A,Flanagan D,Raven A,Hodder M,Nasreddin N,Xue HH,Delorenzi M,Leedham S,Petrova TV,Sansom O,Alitalo K
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Fri Nov 19 00:00:00 EST 2021
Hydrogels Containing Gradients in Vascular Density Reveal Dose-Dependent Role of Angiocrine Cues on Stem Cell Behavior.
Advanced functional materials
Ngo MT,Barnhouse VR,Gilchrist AE,Mahadik BP,Hunter CJ,Hensold JN,Petrikas N,Harley BAC
11-5921-82 was used in Flow cytometry/Cell sorting to report the successful development of a microfluidic device to generate hydrogels containing lateral gradients in vascular density as a means to identify angiocrine signals underlying hematopoietic stem cell culture ex vivo.
Thu Dec 16 00:00:00 EST 2021
Myocardial infarction accelerates breast cancer via innate immune reprogramming.
Nature medicine
Koelwyn GJ,Newman AAC,Afonso MS,van Solingen C,Corr EM,Brown EJ,Albers KB,Yamaguchi N,Narke D,Schlegel M,Sharma M,Shanley LC,Barrett TJ,Rahman K,Mezzano V,Fisher EA,Park DS,Newman JD,Quail DF,Nelson ER,Caan BJ,Jones LW,Moore KJ
11-5921 was used in Flow cytometry/Cell sorting to show that myocardial infarction (MI) accelerates breast cancer outgrowth and cancer-specific mortality in mice and humans. I.
Tue Sep 01 00:00:00 EDT 2020
Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.
Immunity
Tummers B,Mari L,Guy CS,Heckmann BL,Rodriguez DA,Rühl S,Moretti J,Crawford JC,Fitzgerald P,Kanneganti TD,Janke LJ,Pelletier S,Blander JM,Green DR
11-5921-82 was used in Flow Cytometry to suggest an in vivo role of the inflammatory RIPK1-caspase-8-FADD (FADDosome) complex and reveal a FADD-independent inflammatory role of caspase-8 that involves activation of an inflammasome.
Tue Jun 16 00:00:00 EDT 2020
In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors.
Immunity
Zeis P,Lian M,Fan X,Herman JS,Hernandez DC,Gentek R,Elias S,Symowski C,Knöpper K,Peltokangas N,Friedrich C,Doucet-Ladeveze R,Kabat AM,Locksley RM,Voehringer D,Bajenoff M,Rudensky AY,Romagnani C,Grün D,Gasteiger G
11-5921-82 was used in Flow Cytometry to identify local ILCPs and reveal ILCP in situ differentiation and tissue adaptation as a mechanism of ILC maintenance and phenotypic diversification.
Tue Oct 13 00:00:00 EDT 2020
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Cancer cell
Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Mon May 11 00:00:00 EDT 2020
Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development.
Cell stem cell
Crosse EI,Gordon-Keylock S,Rybtsov S,Binagui-Casas A,Felchle H,Nnadi NC,Kirschner K,Chandra T,Tamagno S,Webb DJ,Rossi F,Anderson RA,Medvinsky A
11-5921 was used in Flow cytometry/Cell sorting to identify secreted signals underlying human HSC development, combining spatial transcriptomics analysis of dorsoventral polarized signaling in the aorta with gene expression profiling of sorted cell populations and single cells.
Thu Nov 05 00:00:00 EST 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Systemic Expression of a Viral RdRP Protects against Retrovirus Infection and Disease.
Journal of virology
Miller CM,Barrett BS,Chen J,Morrison JH,Radomile C,Santiago ML,Poeschla EM
11-5921 was used in Flow cytometry/Cell sorting to provide evidence which could have implications for harnessing ISG responses to reduce transmission or control pathogenesis of human retroviral pathogens.
Thu Apr 16 00:00:00 EDT 2020
Ku80-Targeted pH-Sensitive Peptide-PNA Conjugates Are Tumor Selective and Sensitize Cancer Cells to Ionizing Radiation.
Molecular cancer research : MCR
Kaplan AR,Pham H,Liu Y,Oyaghire S,Bahal R,Engelman DM,Glazer PM
11-5921 was used in Flow cytometry/Cell sorting to describes a novel agent, pHLIP-αKu80(γ), which combines PNA antisense and pHLIP technologies to selectively reduce the expression of the DNA repair factor KU80 in tumors and confer tumor-selective radiosensitization.
Mon Jun 01 00:00:00 EDT 2020
Development of an inexpensive Raman-compatible substrate for the construction of a microarray screening platform.
The Analyst
Pastrana-Otero I,Majumdar S,Gilchrist AE,Gorman BL,Harley BAC,Kraft ML
11-5921-82 was used in Flow Cytometry to show that the spectra acquired from individual living cells on functionalized PA gels attached to our custom substrates were of sufficient quality to enable accurate identification of cell phenotypes using PLS-DA models of the cell spectra.
Mon Oct 26 00:00:00 EDT 2020
Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche.
Integrative biology : quantitative biosciences from nano to macro
Gilchrist AE,Harley BAC
11-5921-82 was used in Flow Cytometry to investigate the mechanism of how marrow-derived mesenchymal stromal and progenitor cells impacts hematopoietic stem cells fate decisions.
Fri Jul 10 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Fri May 22 00:00:00 EDT 2020
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Fri May 08 00:00:00 EDT 2020
A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors.
eLife
Crowley L,Cambuli F,Aparicio L,Shibata M,Robinson BD,Xuan S,Li W,Hibshoosh H,Loda M,Rabadan R,Shen MM
11-5921 was used in Flow cytometry/Cell sorting to elucidate new prostate epithelial progenitors, and help resolve long-standing questions about anatomical relationships between the mouse and human prostate.
Fri Sep 11 00:00:00 EDT 2020
Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi.
Nature communications
Hong SP,Yang MJ,Cho H,Park I,Bae H,Choe K,Suh SH,Adams RH,Alitalo K,Lim D,Koh GY
11-5921 was used in Flow cytometry/Cell sorting to demonstrate the heterogeneity of IntSCs and reveal that distinct subsets of villi fibroblasts regulate lacteal integrity through YAP/TAZ-induced VEGF-C secretion.
Fri Aug 14 00:00:00 EDT 2020
Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles.
Cell reports
Camps J,Breuls N,Sifrim A,Giarratana N,Corvelyn M,Danti L,Grosemans H,Vanuytven S,Thiry I,Belicchi M,Meregalli M,Platko K,MacDonald ME,Austin RC,Gijsbers R,Cossu G,Torrente Y,Voet T,Sampaolesi M
11-5921 was used in Flow cytometry/Cell sorting to decomplexify interstitial cell populations in healthy and dystrophic skeletal muscles using single-cell RNA sequencing.
Tue May 05 00:00:00 EDT 2020
ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.
Cell reports
Viaud M,Abdel-Wahab O,Gall J,Ivanov S,Guinamard R,Sore S,Merlin J,Ayrault M,Guilbaud E,Jacquel A,Auberger P,Wang N,Levine RL,Tall AR,Yvan-Charvet L
11-5921 was used in Flow cytometry/Cell sorting to identify somatic mutations in ABCA1 that subvert its anti-proliferative and cholesterol efflux functions and permit the progression of myeloid neoplasms.
Tue Mar 10 00:00:00 EDT 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
11-5921-82 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.
Tue Feb 16 00:00:00 EST 2021
Elucidating the fundamental fibrotic processes driving abdominal adhesion formation.
Nature communications
Foster DS,Marshall CD,Gulati GS,Chinta MS,Nguyen A,Salhotra A,Jones RE,Burcham A,Lerbs T,Cui L,King ME,Titan AL,Ransom RC,Manjunath A,Hu MS,Blackshear CP,Mascharak S,Moore AL,Norton JA,Kin CJ,Shelton AA,Januszyk M,Gurtner GC,Wernig G,Longaker MT
11-5921 was used in Flow cytometry/Cell sorting to present a systematic analysis of mouse and human adhesion tissues.
Thu Aug 13 00:00:00 EDT 2020
Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny.
Cell reports
Simic M,Manosalva I,Spinelli L,Gentek R,Shayan RR,Siret C,Girard-Madoux M,Wang S,de Fabritus L,Verschoor J,Kerdiles YM,Bajenoff M,Stumm R,Golub R,van de Pavert SA
11-5921 was used in Flow cytometry/Cell sorting to identify a major contribution from embryonic hemogenic endothelium, but not the yolk sac, toward LTi progenitors.
Tue Aug 11 00:00:00 EDT 2020
Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1.
iScience
Iwanami N,Takeshita K,Lawir DF,Suetake I,Tajima S,Sikora K,Trancoso I,ÓMeara C,Siamishi I,Takahama Y,Furutani-Seiki M,Kondoh H,Yonezawa Y,Schorpp M,Boehm T
11-5921 was used in Flow cytometry/Cell sorting to identify new recessive dnmt1 alleles in medaka and zebrafish and, guided by the structures of mutant proteins, generated a recessive variant of mouse Dnmt1.
Fri Jul 24 00:00:00 EDT 2020
Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer.
The Journal of clinical investigation
Soukup AA,Zheng Y,Mehta C,Wu J,Liu P,Cao M,Hofmann I,Zhou Y,Zhang J,Johnson KD,Choi K,Keles S,Bresnick EH
11-5921 was used in Flow cytometry/Cell sorting to study the mechanisms underlying how GATA2 enhancer disease mutations impact hematopoiesis and pathology.
Fri Mar 01 00:00:00 EST 2019
Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response.
Science translational medicine
Sharon D,Cathelin S,Mirali S,Di Trani JM,Yanofsky DJ,Keon KA,Rubinstein JL,Schimmer AD,Ketela T,Chan SM
11-5921-82 was used in Flow cytometry/Cell sorting to investigate if inactivation of genes involved in mitochondrial translation restores sensitivity to venetoclax in resistant acute myeloid leukemia cells.
Wed Oct 30 00:00:00 EDT 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
A MST1-FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis.
Nature communications
Kim YH,Choi J,Yang MJ,Hong SP,Lee CK,Kubota Y,Lim DS,Koh GY
11-5921-82 was used in Flow Cytometry to delineate a crucial coupling between extracellular hypoxia and an intracellular reactive oxygen species-MST1-FOXO1 cascade in establishing endothelial tip cell polarity during sprouting angiogenesis.
Tue Feb 19 00:00:00 EST 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
11-5921 was used in Flow cytometry/Cell sorting to determine which chemokines are expressed in dystrophic muscles undergoing tissue remodelling.
Tue Mar 05 00:00:00 EST 2019
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.
Immunity
Hu G,Cui K,Fang D,Hirose S,Wang X,Wangsa D,Jin W,Ried T,Liu P,Zhu J,Rothenberg EV,Zhao K
11-5921 was used in Flow cytometry/Cell sorting to find that abrupt genome-wide changes at all three levels of chromatin organization occur during the transition from double-negative stage 2 (DN2) to DN3, accompanying the T lineage commitment.
Tue Feb 20 00:00:00 EST 2018
CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine.
Cell stem cell
Hirata Y,Furuhashi K,Ishii H,Li HW,Pinho S,Ding L,Robson SC,Frenette PS,Fujisaki J
11-5921-82 was used in Immunohistochemistry to describe a Treg subpopulation that controls hematopoietic stem cell (HSC) quiescence and engraftment.
Thu Mar 01 00:00:00 EST 2018
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
The Journal of clinical investigation
Chennupati V,Veiga DF,Maslowski KM,Andina N,Tardivel A,Yu EC,Stilinovic M,Simillion C,Duchosal MA,Quadroni M,Roberts I,Sankaran VG,MacDonald HR,Fasel N,Angelillo-Scherrer A,Schneider P,Hoang T,Allam R
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Immunocytochemistry
Mon Apr 02 00:00:00 EDT 2018
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
The Journal of clinical investigation
Chennupati V,Veiga DF,Maslowski KM,Andina N,Tardivel A,Yu EC,Stilinovic M,Simillion C,Duchosal MA,Quadroni M,Roberts I,Sankaran VG,MacDonald HR,Fasel N,Angelillo-Scherrer A,Schneider P,Hoang T,Allam R
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Immunocytochemistry
Mon Apr 02 00:00:00 EDT 2018
Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels.
Development (Cambridge, England)
Zhang Y,Daubel N,Stritt S,Mäkinen T
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Immunofluorescence
Thu Feb 08 00:00:00 EST 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis.
Scientific reports
Saranchova I,Han J,Zaman R,Arora H,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer CG,Welch I,Takei F,Jefferies WA
11-5921 was used in Flow cytometry/Cell sorting to study the role of type 2 innate lymphoid cells in enhancing anti-cancer immunity and controlling metastasis.
Tue Feb 13 00:00:00 EST 2018
Group 2 innate lymphoid cells protect lung endothelial cells from pyroptosis in sepsis.
Cell death & disease
Lai D,Tang J,Chen L,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Fang X,Shu Q,Fan J
11-5921 was used in Flow cytometry/Cell sorting to describe the function of ILC2 in the regulation of lung inflammation by protecting lung endothelial cell from pyroptosis.
Tue Mar 06 00:00:00 EST 2018
MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity.
Frontiers in immunology
Knolle MD,Chin SB,Rana BMJ,Englezakis A,Nakagawa R,Fallon PG,Git A,McKenzie ANJ
11-5921 was used in Flow cytometry/Cell sorting to identify a subset of micro-RNAs that are regulated upon group-2 innate lymphoid cells (ILC2) activation, and establish a specific role for miR-155 in regulating ILC2 survival following activation.
Mon Sep 30 00:00:00 EDT 2019
In utero nanoparticle delivery for site-specific genome editing.
Nature communications
Ricciardi AS,Bahal R,Farrelly JS,Quijano E,Bianchi AH,Luks VL,Putman R,López-Giráldez F,Coşkun S,Song E,Liu Y,Hsieh WC,Ly DH,Stitelman DH,Glazer PM,Saltzman WM
Tue Jun 26 00:00:00 EDT 2018
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Cell stem cell
Schneider RK,Mullally A,Dugourd A,Peisker F,Hoogenboezem R,Van Strien PMH,Bindels EM,Heckl D,Büsche G,Fleck D,Müller-Newen G,Wongboonsin J,Ventura Ferreira M,Puelles VG,Saez-Rodriguez J,Ebert BL,Humphreys BD,Kramann R
11-5921 was used in Flow cytometry/Cell sorting to study the cellular origin of bone marrow fibrosis.
Thu Jun 01 00:00:00 EDT 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation.
The Journal of experimental medicine
McGarvey AC,Rybtsov S,Souilhol C,Tamagno S,Rice R,Hills D,Godwin D,Rice D,Tomlinson SR,Medvinsky A
11-5921 was used in Flow cytometry/Cell sorting to identify novel secreted regulators of haematopoietic stem cell maturation.
Mon Dec 04 00:00:00 EST 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
11-5921 was used in Flow cytometry/Cell sorting to propose that Samd14-Enh and an ensemble of anemia-responsive enhancers are essential for erythrocyte regeneration in stress erythropoiesis.
Mon Aug 07 00:00:00 EDT 2017
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Pishesha N,Bilate AM,Wibowo MC,Huang NJ,Li Z,Deshycka R,Bousbaine D,Li H,Patterson HC,Dougan SK,Maruyama T,Lodish HF,Ploegh HL
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Tue Mar 21 00:00:00 EDT 2017
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Wed Nov 29 00:00:00 EST 2017
Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown.
JCI insight
Ogura S,Kurata K,Hattori Y,Takase H,Ishiguro-Oonuma T,Hwang Y,Ahn S,Park I,Ikeda W,Kusuhara S,Fukushima Y,Nara H,Sakai H,Fujiwara T,Matsushita J,Ema M,Hirashima M,Minami T,Shibuya M,Takakura N,Kim P,Miyata T,Ogura Y,Uemura A
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Immunohistochemistry
Thu Feb 09 00:00:00 EST 2017
Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program.
Cell reports
Mehta C,Johnson KD,Gao X,Ong IM,Katsumura KR,McIver SC,Ranheim EA,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Tue Sep 19 00:00:00 EDT 2017
Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Wellcome open research
Dutton EE,Camelo A,Sleeman M,Herbst R,Carlesso G,Belz GT,Withers DR
11-5921-82 was used in Flow Cytometry to compare the innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Sat Jan 09 00:00:00 EST 2021
Flow cytometric single cell analysis reveals heterogeneity between adipose depots.
Adipocyte
Boumelhem BB,Assinder SJ,Bell-Anderson KS,Fraser ST
11-5921-82 was used in Flow cytometry/Cell sorting to report a system for analyzing live adipocytes from different adipose depots in the adult mouse.
Mon Apr 03 00:00:00 EDT 2017
Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.
PloS one
Zhao Y,Wu K,Nguyen C,Smbatyan G,Melendez E,Higuchi Y,Chen Y,Kahn M
11-5921 was used in Flow cytometry/Cell sorting to report that the small molecule YH250 stimulates hematopoiesis in lethally or sublethally irradiated mice.
Tue Sep 26 00:00:00 EDT 2017
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
11-5921 was used in Flow cytometry/Cell sorting to study how OTULIN may be critical in restraining life-threatening spontaneous inflammation and maintaining immune homeostasis.
Thu Aug 25 00:00:00 EDT 2016
Innate lymphoid cells contribute to allergic airway disease exacerbation by obesity.
The Journal of allergy and clinical immunology
Everaere L,Ait-Yahia S,Molendi-Coste O,Vorng H,Quemener S,LeVu P,Fleury S,Bouchaert E,Fan Y,Duez C,de Nadai P,Staels B,Dombrowicz D,Tsicopoulos A
11-5921 was used in Flow cytometry/Cell sorting to indicate that high-fat diet-induced obesity might exacerbate allergic airway inflammation through mechanisms involving ILC2s and ILC3s.
Tue Nov 01 00:00:00 EDT 2016
The LMO2 oncogene regulates DNA replication in hematopoietic cells.
Proceedings of the National Academy of Sciences of the United States of America
Sincennes MC,Humbert M,Grondin B,Lisi V,Veiga DF,Haman A,Cazaux C,Mashtalir N,Affar el B,Verreault A,Hoang T
11-5921-82 was used in Flow cytometry/Cell sorting to show that LMO2 is recruited to DNA replication origins by interaction with three essential replication enzymes: DNA polymerase delta, DNA primase, and minichromosome 6.
Tue Feb 02 00:00:00 EST 2016
A Role for Regulatory T Cells in a Murine Model of Epicutaneous Toluene Diisocyanate Sensitization.
Toxicological sciences : an official journal of the Society of Toxicology
Long CM,Marshall NB,Lukomska E,Kashon ML,Meade BJ,Shane H,Anderson SE
11-5921 was used in Flow cytometry/Cell sorting to delineate the immunologic mechanisms of chemical-induced allergic disease.
Fri Jul 01 00:00:00 EDT 2016
Murine Model for Preclinical Studies of Var2CSA-Mediated Pathology Associated with Malaria in Pregnancy.
Infection and immunity
de Moraes LV,Dechavanne S,Sousa PM,Barateiro A,Cunha SF,Nunes-Silva S,Lima FA,Murillo O,Marinho CRF,Gangnard S,Srivastava A,Braks JA,Janse CJ,Gamain B,Franke-Fayard B,Penha-Gonçalves C
11-5921 was used in Flow cytometry/Cell sorting to provide a tool for preclinical evaluation of protection against PM induced by approaches that target var2CSA.
Wed Jun 01 00:00:00 EDT 2016
Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.
Biochemical and biophysical research communications
Qu X,Li J,Baldwin HS
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Immunofluorescence
Fri Feb 12 00:00:00 EST 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2016
Regulation of Prostate Development and Benign Prostatic Hyperplasia by Autocrine Cholinergic Signaling via Maintaining the Epithelial Progenitor Cells in Proliferating Status.
Stem cell reports
Wang N,Dong BJ,Quan Y,Chen Q,Chu M,Xu J,Xue W,Huang YR,Yang R,Gao WQ
11-5921 was used in Flow cytometry/Cell sorting to investigate the role of autocrine cholinergic signaling (ASC) in prostate development, showing that development is regulated by ASC.
Tue May 10 00:00:00 EDT 2016
miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
Nature communications
Jiang X,Hu C,Arnovitz S,Bugno J,Yu M,Zuo Z,Chen P,Huang H,Ulrich B,Gurbuxani S,Weng H,Strong J,Wang Y,Li Y,Salat J,Li S,Elkahloun AG,Yang Y,Neilly MB,Larson RA,Le Beau MM,Herold T,Bohlander SK,Liu PP,Zhang J,Li Z,He C,Jin J,Hong S,Chen J
11-5921 was used in Flow cytometry/Cell sorting to investigate the anti-tumourigenic role of miR-22, showing that it has an anti-tumour role in acute myeloid leukaemia.
Tue Apr 26 00:00:00 EDT 2016
The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis.
PloS one
Braun J,Meixner A,Brachner A,Foisner R
11-5921 was used in Flow cytometry/Cell sorting to test whether ANKLE1 may contribute to Holliday junction resolution during DNA repair in mice.
Fri Aug 12 00:00:00 EDT 2016
PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal.
Nature
Lee HY,Gao X,Barrasa MI,Li H,Elmes RR,Peters LL,Lodish HF
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Thu Jun 25 00:00:00 EDT 2015
MicroRNA-451 exacerbates lipotoxicity in cardiac myocytes and high-fat diet-induced cardiac hypertrophy in mice through suppression of the LKB1/AMPK pathway.
Circulation research
Kuwabara Y,Horie T,Baba O,Watanabe S,Nishiga M,Usami S,Izuhara M,Nakao T,Nishino T,Otsu K,Kita T,Kimura T,Ono K
11-5921 was used in Flow cytometry/Cell sorting to elucidate the mechanisms underlying the involvement of miR-451 in diabetic cardiomyopathy.
Fri Jan 16 00:00:00 EST 2015
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.
The Journal of clinical investigation
Hadland BK,Varnum-Finney B,Poulos MG,Moon RT,Butler JM,Rafii S,Bernstein ID
11-5921 was used in Flow cytometry/Cell sorting to investigate the critical niche components and resident signals required for hematopoietic stem cell induction and self-renewal ex vivo.
Fri May 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
11-5921 was used in Flow cytometry/Cell sorting to illustrate a paradigm in which cis-elements in a locus differentially control stem and progenitor cell transitions.
Tue Sep 01 00:00:00 EDT 2015
Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.
American journal of hematology
Ludwig LS,Cho H,Wakabayashi A,Eng JC,Ulirsch JC,Fleming MD,Lodish HF,Sankaran VG
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Premature thymic involution is independent of structural plasticity of the thymic stroma.
European journal of immunology
Franckaert D,Schlenner SM,Heirman N,Gill J,Skogberg G,Ekwall O,Put K,Linterman MA,Dooley J,Liston A
11-5921 was used in Flow cytometry/Cell sorting to investigate thymic involution in FVB/N mice, showing that disruption of the epithelial-endothelial relationship and a progressive loss of pro-T cells precedes involution, and loss of pro-T cells is sufficient to drive premature involution, suggesting that pro-T cells are the main driver of involution.
Fri May 01 00:00:00 EDT 2015
mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function.
Journal of immunology (Baltimore, Md. : 1950)
Schaffert SA,Loh C,Wang S,Arnold CP,Axtell RC,Newell EW,Nolan G,Ansel KM,Davis MM,Steinman L,Chen CZ
11-5921 was used in Flow cytometry/Cell sorting to explore the physiological control of tolerance by manipulating microRNA gene products.
Sat Aug 15 00:00:00 EDT 2015
Multi-Drug Resistance ABC Transporter Inhibition Enhances Murine Ventral Prostate Stem/Progenitor Cell Differentiation.
Stem cells and development
Samant MD,Jackson CM,Felix CL,Jones AJ,Goodrich DW,Foster BA,Huss WJ
11-5921 was used in Flow cytometry/Cell sorting to investigate the role of MDR-ABC efflux transporters in prostate differentiation and epithelium regeneration in the murine prostate.
Fri May 15 00:00:00 EDT 2015
Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro.
Cell transplantation
Nakatsuka R,Matsuoka Y,Uemura Y,Sumide K,Iwaki R,Takahashi M,Fujioka T,Sasaki Y,Sonoda Y
11-5921 was used in Flow cytometry/Cell sorting to demonstrate that prospectively isolated murine PDGFRα and Sca-1 double-positive dental pulp stem cells could support primitive human CD34+ and CD34- hematopoietic stem cells in vitro.
Wed Sep 16 00:00:00 EDT 2015
Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality.
Nature communications
Alvarez S,Díaz M,Flach J,Rodriguez-Acebes S,López-Contreras AJ,Martínez D,Cañamero M,Fernández-Capetillo O,Isern J,Passegué E,Méndez J
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Immunohistochemistry
Mon Oct 12 00:00:00 EDT 2015
The Spleen Plays No Role in Nephrotoxic Serum Nephritis, but Constitutes a Place of Compensatory Haematopoiesis.
PloS one
Artinger K,Kirsch AH,Aringer I,Schabhüttl C,Rosenkranz AR,Eller P,Rho E,Eller K
11-5921 was used in Flow cytometry/Cell sorting to study how splenectomy does not influence the course of NTS, but is involved in concomitant anaemia.
Fri May 06 00:00:00 EDT 2016
Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis.
Cell reports
Morgado-Palacin L,Varetti G,Llanos S,Gómez-López G,Martinez D,Serrano M
11-5921 was used in Flow cytometry/Cell sorting to conclude that Rpl11-deficient mice recapitulate DBA disorder, including cancer predisposition.
Tue Oct 27 00:00:00 EDT 2015
MtDNA mutagenesis impairs elimination of mitochondria during erythroid maturation leading to enhanced erythrocyte destruction.
Nature communications
Ahlqvist KJ,Leoncini S,Pecorelli A,Wortmann SB,Ahola S,Forsström S,Guerranti R,De Felice C,Smeitink J,Ciccoli L,Hämäläinen RH,Suomalainen A
11-5921 was used in Immunofluorescence to investigate whether increased mitochondrial DNA mutagenesis underlies anaemia.
Mon Mar 09 00:00:00 EDT 2015
Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment.
The Journal of biological chemistry
Huang Y,Hamana T,Liu J,Wang C,An L,You P,Chang JYF,Xu J,Jin C,Zhang Z,McKeehan WL,Wang F
11-5921 was used in Flow cytometry/Cell sorting to indicate that FGFR2 signaling is critical for preserving stemness and preventing differentiation of Prostate stem cells (P-SCs).
Fri Jul 17 00:00:00 EDT 2015
Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate.
Nature cell biology
Lim A,Shin K,Zhao C,Kawano S,Beachy PA
11-5921 was used in Flow cytometry/Cell sorting to investigate the role of Hh signalling in adult prostate branching morphogenesis.
Mon Dec 01 00:00:00 EST 2014
CLEC-2 is required for development and maintenance of lymph nodes.
Blood
Bénézech C,Nayar S,Finney BA,Withers DR,Lowe K,Desanti GE,Marriott CL,Watson SP,Caamaño JH,Buckley CD,Barone F
11-5921 was used in Flow cytometry/Cell sorting to investigate the role that CLEC-2 plays in the development and maintenance of lymph nodes.
Thu May 15 00:00:00 EDT 2014
Differentiation ability of multipotent hematopoietic stem/progenitor cells detected by a porcine specific anti-CD117 monoclonal antibody.
Bioscience trends
Ohshima S,Mori S,Shigenari A,Miyamoto A,Takasu M,Imaeda N,Nunomura S,Okayama Y,Tanaka M,Kitagawa H,Kulski JK,Inoko H,Ando A,Kametani Y
11-5921 was used in Flow cytometry/Cell sorting to reveal that the swine BM CD117+ cells possess hematopoietic stem/progenitor activity.
Mon Dec 01 00:00:00 EST 2014
Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor.
Stem cells (Dayton, Ohio)
Povinelli BJ,Nemeth MJ
11-5921 was used in Flow cytometry/Cell sorting to study whether Ryk protein regulates the response of haematopoietic stem cells to Wnt5a.
Wed Jan 01 00:00:00 EST 2014
Cutting edge: CD8+ recent thymic emigrants exhibit increased responses to low-affinity ligands and improved access to peripheral sites of inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Berkley AM,Fink PJ
11-5921-82 was used in Flow Cytometry to investigate if the maturation state of peripheral T cells impacts the response to bacterial infection due to intrinsic differences in TCR signaling.
Wed Oct 01 00:00:00 EDT 2014
Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection.
Journal of immunology (Baltimore, Md. : 1950)
Jie Z,Liang Y,Hou L,Dong C,Iwakura Y,Soong L,Cong Y,Sun J
11-5921 was used in Flow cytometry/Cell sorting to investigate the source and regulation of the IL-17 surge in the liver microenvironment that occurs early in the response to viral infection.
Tue Apr 01 00:00:00 EDT 2014
DNA methylation of E-cadherin is a priming mechanism for prostate development.
Developmental biology
Keil KP,Abler LL,Mehta V,Altmann HM,Laporta J,Plisch EH,Suresh M,Hernandez LL,Vezina CM
11-5921 was used in Flow cytometry/Cell sorting to investigate the parallels between the signalling during prostate cancer development and prostate organogenesis.
Sat Mar 15 00:00:00 EDT 2014
LSD1 promotes oxidative metabolism of white adipose tissue.
Nature communications
Duteil D,Metzger E,Willmann D,Karagianni P,Friedrichs N,Greschik H,Günther T,Buettner R,Talianidis I,Metzger D,Schüle R
11-5921 was used in Flow cytometry/Cell sorting to investigate the role of LSD1 as a key regulator of oxidative metabolism of white adipose tissue.
Tue Jun 10 00:00:00 EDT 2014
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Nature cell biology
Chou J,Lin JH,Brenot A,Kim JW,Provot S,Werb Z
11-5921 was used in Flow cytometry/Cell sorting to study how the GATA3-miR-29b axis regulates the tumour microenvironment, and inhibits metastasis to open up possibilities for therapeutic intervention in breast cancer.
Fri Feb 01 00:00:00 EST 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children.
Atherosclerosis
Tolani S,Pagler TA,Murphy AJ,Bochem AE,Abramowicz S,Welch C,Nagareddy PR,Holleran S,Hovingh GK,Kuivenhoven JA,Tall AR
11-5921 was used in Flow cytometry/Cell sorting to suggest that in mice, a balance of cholesterol uptake and efflux mechanisms may be one factor in driving HSPC proliferation and monocytosis.
Mon Jul 01 00:00:00 EDT 2013
Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.
PloS one
Halemano K,Barrett BS,Li SX,Harper MS,Smith DS,Heilman KJ,Santiago ML
11-5921 was used in Flow cytometry/Cell sorting to show that B-tropic FV infection of 129P2 mice may be a useful model to study the immunological pathways induced by retroviral capsid restriction.
Wed Sep 11 00:00:00 EDT 2013
A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with Nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype.
Virology journal
Ellis BL,Hirsch ML,Barker JC,Connelly JP,Steininger RJ,Porteus MH
11-5921 was used in Flow cytometry/Cell sorting to produce a comprehensive study of the transduction efficiency of viral vectors.
Wed Mar 06 00:00:00 EST 2013
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Thu May 10 00:00:00 EDT 2012
Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis.
Blood
Carbonneau CL,Despars G,Rojas-Sutterlin S,Fortin A,Le O,Hoang T,Beauséjour CM
11-5921 was used in Flow cytometry/Cell sorting to investigate the effect of ionizing radiation on murine bone marrow-derived stromal cell populations, and overall bone marrow homeostasis.
Thu Jan 19 00:00:00 EST 2012
IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Blood
Balkhi MY,Willette-Brown J,Zhu F,Chen Z,Liu S,Guttridge DC,Karin M,Hu Y
11-5921-82 was used in Flow Cytometry to demonstrate that IKKα regulates B-lineage commitment via combined canonical and noncanonical NF-κB transcriptional activities to target Pax5 expression during hematopoiesis.
Thu Jun 07 00:00:00 EDT 2012
Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.
The Journal of clinical investigation
Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH
11-5921 was used in Flow cytometry/Cell sorting to identify a novel mutation in a GATA2 cis-element which causes deficits in haematopoietic stem/progenitor activity.
Mon Oct 01 00:00:00 EDT 2012
Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling.
Developmental cell
Chhabra A,Lechner AJ,Ueno M,Acharya A,Van Handel B,Wang Y,Iruela-Arispe ML,Tallquist MD,Mikkola HK
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Immunohistochemistry
Tue Mar 13 00:00:00 EDT 2012
CCAAT/enhancer-binding protein β (C/EBPβ) expression regulates dietary-induced inflammation in macrophages and adipose tissue in mice.
The Journal of biological chemistry
Rahman SM,Janssen RC,Choudhury M,Baquero KC,Aikens RM,de la Houssaye BA,Friedman JE
11-5921 was used in Flow cytometry/Cell sorting to demonstrate that a high fat diet or palmitate exposure triggers C/EBPβ expression that controls expression of distinct aspects of alternative macrophage activation.
Fri Oct 05 00:00:00 EDT 2012
Isolation, cultivation and characterization of adult murine prostate stem cells.
Nature protocols
Lukacs RU,Goldstein AS,Lawson DA,Cheng D,Witte ON
11-5921 was used in Flow cytometry/Cell sorting to develop a protocol to isolate, cultivate and characterise adult murine prostate stem cells, allowing further studies in organ replenishment and their role in cancer initiation.
Thu Apr 01 00:00:00 EDT 2010
Murine neonates develop vigorous in vivo cytotoxic and Th1/Th2 responses upon exposure to low doses of NIMA-like alloantigens.
Blood
Opiela SJ,Levy RB,Adkins B
11-5921-82 was used in Flow Cytometry to study the different immunological responses to noninherited maternal antigens.
Fri Aug 15 00:00:00 EDT 2008
Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes.
Journal of the National Cancer Institute
Wu MY,Eldin KW,Beaudet AL
11-5921 was used in Flow cytometry/Cell sorting to investigate the role of epigenetic alterations in tumorigenesis.
Wed Sep 03 00:00:00 EDT 2008
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
11-5921 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
11-5921 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation.
International immunology
Ohno S,Sato T,Kohu K,Takeda K,Okumura K,Satake M,Habu S
11-5921 was used in Flow cytometry/Cell sorting to investigate the role of Runx family proteins in NK cells, showing that they are involved in regulation of CD122, Ly49 family and IFN-gamma expression during differentiation.
Tue Jan 01 00:00:00 EST 2008
Differentiation of mouse embryonic stem cells into blood.
Current protocols in stem cell biology
Ma YD,Lugus JJ,Park C,Choi K
11-5921 was used in Flow cytometry/Cell sorting to develop protocols for the maintenance and differentiation of mouse embryonic stem cells into hematopoietic progenitors.
Tue Jul 01 00:00:00 EDT 2008
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling.
Proceedings of the National Academy of Sciences of the United States of America
Tsuji M,Shinkura R,Kuroda K,Yabe D,Honjo T
11-5921-82 was used in Flow Cytometry to o investigate where and how Notch regulates early T cell differentiation by using specific up-regulation of Notch signaling by Mint knockout.
Tue Jan 30 00:00:00 EST 2007
Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis.
European journal of immunology
Dluzniewska J,Zou L,Harmon IR,Ellingson MT,Peterson EJ
11-5921-82 was used in Flow Cytometry to highlight the dynamic regulation of ADAP during T cell maturation and document expression patterns that suggest a possible role for ADAP in development of non-T hematopoietic lineages.
Thu Nov 01 00:00:00 EDT 2007
Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin.
The EMBO journal
Vassen L,Fiolka K,Möröy T
Published figure using TER-119 monoclonal antibody (Product # 11-5921-82) in Flow Cytometry
Wed Jun 07 00:00:00 EDT 2006
