Invitrogen

F4/80 Monoclonal Antibody (BM8), eFluor™ 450, eBioscience™

FIGURE: 1 / 98

F4/80 Antibody (48-4801-82) in Flow

Staining of mouse resident peritoneal exudate cells with Anti-Mouse CD11b PE (Product # 12-0112-82) and 0.25 µg of Rat IgG2a K Isotype Control eFluor® 450 (Product # 48-4321-82) (left) or 0.25 µg of Anti-Mouse F4/80 Antigen eFluor® 450 (right). Cells in the large scatter population were used for analysis.

F4/80 Antibody in Immunocytochemistry (ICC/IF)

F4/80 Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)

F4/80 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)

F4/80 Antibody in Immunocytochemistry, Immunohistochemistry, Flow Cytometry (ICC/IF, IHC, Flow)

F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

F4/80 Antibody in Immunohistochemistry (Frozen) (IHC (F))

F4/80 Antibody in Immunohistochemistry, Immunohistochemistry (Frozen) (IHC, IHC (F))

F4/80 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

Product Details

48-4801-82

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

View 147 publications 147 publications

Immunohistochemistry (Paraffin) (IHC (P))

View 4 publications 4 publications

Immunohistochemistry (PFA fixed) (IHC (PFA))

View 2 publications 2 publications

Immunohistochemistry (Frozen) (IHC (F))

View 7 publications 7 publications

Immunocytochemistry (ICC/IF)

View 41 publications 41 publications

Flow Cytometry (Flow)

0.5 µg/test

View 245 publications 245 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Mouse

Published species

Hamster, Human, Mouse, Rat

Host/Isotype

Rat / IgG2a, kappa

Recommended Isotype Control

Rat IgG2a kappa Isotype Control (eBR2a), eFluor™ 450, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

BM8

Conjugate

eFluor™ 450 eFluor™ 450 eFluor™ 450

Excitation/Emission Max

405/445 nm View spectra

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1548747

Product Specific Information

Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 160 kDa surface receptor. It belongs to the EGF-TM7 family of proteins. As such it contains seven EGF-like domains on its extracellular N-terminus, seven transmembrane spanning sequences, and an intracellular C-terminal domain showing homology to other TM7 superfamily members. The F4/80 antigen is expressed by a majority of mature macrophages and is one of the best markers for this population of cells. However, other cell types, such as peritoneal eosinophils, Langerhans cells, and some other dendritic cell subtypes, have been reported to express this antigen as well. Expression of F4/80 commences during early myeloid development in vivo and can be upregulated on BM cells stimulated in vitro with M-CSF. Some populations of macrophages, especially in the lymphoid microenvironment, may be devoid of F4/80.

Applications Reported: This BM8 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This BM8 antibody has been tested by flow cytometric analysis of mouse resident peritoneal exudate cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.

Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice.

Cellular & molecular biology letters

Qi H,Zheng Z,Liu Q

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Oct 12 00:00:00 EDT 2023

HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation.

eLife

Scinicariello S,Soderholm A,Schäfer M,Shulkina A,Schwartz I,Hacker K,Gogova R,Kalis R,Froussios K,Budroni V,Bestehorn A,Clausen T,Kovarik P,Zuber J,Versteeg GA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Mar 24 00:00:00 EDT 2023

YAP/STAT3 inhibited CD8⁺ T cells activity in the breast cancer immune microenvironment by inducing M2 polarization of tumor-associated macrophages.

Cancer medicine

Wang C,Shen N,Guo Q,Tan X,He S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2023

Gene deletion of long-chain acyl-CoA synthetase 4 attenuates xenobiotic chemical-induced lung injury via the suppression of lipid peroxidation.

Redox biology

Tomitsuka Y,Imaeda H,Ito H,Asou I,Ohbayashi M,Ishikawa F,Kuwata H,Hara S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2023

Role of low-intensity pulsed ultrasound in regulating macrophage polarization to accelerate tendon-bone interface repair.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Xu Z,Li S,Wan L,Hu J,Lu H,Zhang T

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2023

Dipeptidyl peptidase 4 inhibitor reduces tumor-associated macrophages and enhances anti-PD-L1-mediated tumor suppression in non-small cell lung cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Zuo B,Li T,Liu X,Wang S,Cheng J,Liu X,Cui W,Shi H,Ling C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Nov 01 00:00:00 EDT 2023

SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization.

Journal of advanced research

Lee JH,Lee SH,Lee EH,Cho JY,Song DK,Lee YJ,Kwon TK,Oh BC,Cho KW,Osborne TF,Jeon TI,Im SS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

GPR84 regulates pulmonary inflammation by modulating neutrophil functions.

Acta pharmacologica Sinica

Wang SW,Zhang Q,Lu D,Fang YC,Yan XC,Chen J,Xia ZK,Yuan QT,Chen LH,Zhang YM,Nan FJ,Xie X

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2023

Platelet factors attenuate inflammation and rescue cognition in ageing.

Nature

Schroer AB,Ventura PB,Sucharov J,Misra R,Chui MKK,Bieri G,Horowitz AM,Smith LK,Encabo K,Tenggara I,Couthouis J,Gross JD,Chan JM,Luke A,Villeda SA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2023

Mechanobiology of Ferroptotic Cancer Cells as a Novel "Eat-Me" Signal: Regulating Efferocytosis through Layer-by-Layer Coating.

Advanced healthcare materials

Van der Meeren L,Efimova I,Demuynck R,Parakhonskiy B,Krysko DV,Skirtach AG

48-4801-82 was used in Flow Cytometry to demonstrate the crucial role of mechanobiology of dead cells in regulating their efferocytosis by macrophages which can be exploited for the development of novel therapeutic strategies for diseases where modulation of efferocytosis can be potentially beneficial and for the design of drug delivery systems for cancer therapy.

Wed Nov 01 00:00:00 EDT 2023

Loss of SENP3 mediated the formation of nasal polyps in nasal mucosal inflammation by increasing alternative activated macrophage.

Immunity, inflammation and disease

Bao X,Liu B,Jiang Y,Feng T,Cao W,Shi J,Jiang Y,Chen X,Yang J,Li J,Zhou Z

48-4801-82 was used in Flow cytometry/Cell sorting to explore how SENP3 influenced the outcome of chronic rhinosinusitis (CRS) by altering macrophage function, that is, the formation of NPs.

Wed Feb 01 00:00:00 EST 2023

Testicular exosomes disturb the immunosuppressive phenotype of testicular macrophages mediated by miR-155-5p in uropathogenic Escherichia coli-induced orchitis.

Asian journal of andrology

Xu J,He C,Fang YW,Hu ZY,Peng ML,Chen YY,Su YF,Liu CY,Zhang HP,Zhao K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Apr 28 00:00:00 EDT 2023

Testicular exosomes disturb the immunosuppressive phenotype of testicular macrophages mediated by miR-155-5p in uropathogenic Escherichia coli-induced orchitis.

Asian journal of andrology

Xu J,He C,Fang YW,Hu ZY,Peng ML,Chen YY,Su YF,Liu CY,Zhang HP,Zhao K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Apr 28 00:00:00 EDT 2023

Single-cell sequencing reveals homogeneity and heterogeneity of the cytopathological mechanisms in different etiology-induced AKI.

Cell death & disease

Chen Z,Li Y,Yuan Y,Lai K,Ye K,Lin Y,Lan R,Chen H,Xu Y

48-4801-82 was used in Flow Cytometry to provide a potent resource for understanding the pathogenesis of acute kidney injury AKI and early intervention in AKI progression at single-cell resolution.

Thu May 11 00:00:00 EDT 2023

Overexpression of lipocalin 2 in PBX1-deficient decidual NK cells promotes inflammation at the maternal-fetal interface.

American journal of reproductive immunology (New York, N.Y. : 1989)

An X,Qin J,Hu X,Zhou Y,Fu B,Wei H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.

Materials today. Bio

Huang J,Leng X,Jiang T,Xu L,Zheng J,Fang M,Wang J,Wang Z,Zhang L

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sat Apr 01 00:00:00 EDT 2023

Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.

iScience

Gonzatti MB,Freire BM,Antunes MM,de Menezes GB,Talbot J,Peron JPS,Basso AS,Keller AC

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Oct 20 00:00:00 EDT 2023

Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.

iScience

Gonzatti MB,Freire BM,Antunes MM,de Menezes GB,Talbot J,Peron JPS,Basso AS,Keller AC

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Oct 20 00:00:00 EDT 2023

Low-intensity pulsed ultrasound promotes skeletal muscle regeneration via modulating the inflammatory immune microenvironment.

International journal of biological sciences

Qin H,Luo Z,Sun Y,He Z,Qi B,Chen Y,Wang J,Li C,Lin W,Han Z,Zhu Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Mar 20 00:00:00 EDT 2023

Streptococcus agalactiae cadD alleviates metal stress and promotes intracellular survival in macrophages and ascending infection during pregnancy.

Nature communications

Korir ML,Doster RS,Lu J,Guevara MA,Spicer SK,Moore RE,Francis JD,Rogers LM,Haley KP,Blackman A,Noble KN,Eastman AJ,Williams JA,Damo SM,Boyd KL,Townsend SD,Henrique Serezani C,Aronoff DM,Manning SD,Gaddy JA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Sep 14 00:00:00 EDT 2022

Hepatocyte-Specific Deletion of HIF2α Prevents NASH-Related Liver Carcinogenesis by Decreasing Cancer Cell Proliferation.

Cellular and molecular gastroenterology and hepatology

Foglia B,Sutti S,Cannito S,Rosso C,Maggiora M,Autelli R,Novo E,Bocca C,Villano G,Ramavath NN,Younes R,Tusa I,Rovida E,Pontisso P,Bugianesi E,Albano E,Parola M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Apr 04 00:00:00 EDT 2022

Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice.

Nature communications

Weber AA,Yang X,Mennillo E,Ding J,Watrous JD,Jain M,Chen S,Karin M,Tukey RH

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Jul 27 00:00:00 EDT 2022

CD146 Associates with Gp130 to Control a Macrophage Pro-inflammatory Program That Regulates the Metabolic Response to Obesity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Duan H,Jing L,Xiang J,Ju C,Wu Z,Liu J,Ma X,Chen X,Liu Z,Feng J,Yan X

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2022

Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis.

Nature communications

Zhao M,Shao F,Yu D,Zhang J,Liu Z,Ma J,Xia P,Wang S

48-4801-82 was used in Flow cytometry/Cell sorting to show that ILC2s undergo translocation via the lung-gut axis upon IL-33 treatment.

Fri Dec 09 00:00:00 EST 2022

Role of circular RNA cdr1as in modulation of macrophage phenotype.

Life sciences

Gonzalez C,Cimini M,Cheng Z,Benedict C,Wang C,Trungcao M,Mallaredy V,Rajan S,Garikipati VNS,Kishore R

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Nov 15 00:00:00 EST 2022

A ROS-responsive, self-immolative and self-reporting hydrogen sulfide donor with multiple biological activities for the treatment of myocardial infarction.

Bioactive materials

Yao M,Lu Y,Shi L,Huang Y,Zhang Q,Tan J,Hu P,Zhang J,Luo G,Zhang N

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Mar 01 00:00:00 EST 2022

A ROS-responsive, self-immolative and self-reporting hydrogen sulfide donor with multiple biological activities for the treatment of myocardial infarction.

Bioactive materials

Yao M,Lu Y,Shi L,Huang Y,Zhang Q,Tan J,Hu P,Zhang J,Luo G,Zhang N

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Mar 01 00:00:00 EST 2022

Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.

Nature communications

Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L

48-4801-82 was used in Flow Cytometry to demonstrate that Lin28B promotes lung metastasis of breast cancer by building an immune-suppressive pre-metastatic niche.

Wed Feb 16 00:00:00 EST 2022

Combination of a STAT3 inhibitor with anti-PD-1 immunotherapy is an effective treatment regimen for a vemurafenib-resistant melanoma.

Molecular therapy oncolytics

Kim TW,Kim Y,Keum H,Jung W,Kang M,Jon S

48-4801-82 was used in Flow cytometry/Cell sorting to investigate the antitumor efficacy and TME remodeling by APTSTAT3-9R, a cell-permeable STAT3 inhibitory peptide, as a strategy to treat vemurafenib-resistant melanoma.

Thu Sep 15 00:00:00 EDT 2022

Wound healing in aged skin exhibits systems-level alterations in cellular composition and cell-cell communication.

Cell reports

Vu R,Jin S,Sun P,Haensel D,Nguyen QH,Dragan M,Kessenbrock K,Nie Q,Dai X

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Aug 02 00:00:00 EDT 2022

GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy.

Cell death & disease

Wang Y,Li Y,Chen Z,Yuan Y,Su Q,Ye K,Chen C,Li G,Song Y,Chen H,Xu Y

48-4801-82 was used in Flow cytometry/Cell sorting to investigate the underlying molecular mechanism behind the promotion of renal fibrosis by inflammatory cells.

Mon Aug 08 00:00:00 EDT 2022

MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.

Cancer cell

Ueda K,Kumari R,Schwenger E,Wheat JC,Bohorquez O,Narayanagari SR,Taylor SJ,Carvajal LA,Pradhan K,Bartholdy B,Todorova TI,Goto H,Sun D,Chen J,Shan J,Song Y,Montagna C,Xiong S,Lozano G,Pellagatti A,Boultwood J,Verma A,Steidl U

48-4801-82 was used in Flow cytometry/Cell sorting to identify MDMX overexpression as a pervasive preleukemic-to-AML transition mechanism in different genetically driven disease subtypes, and reveal Wnt/β-Catenin as a non-canonical MDMX-driven pathway with therapeutic potential for progression prevention and cancer interception.

Mon Apr 12 00:00:00 EDT 2021

PDGF-D activation by macrophage-derived uPA promotes AngII-induced cardiac remodeling in obese mice.

The Journal of experimental medicine

Cheng YW,Zhang ZB,Lan BD,Lin JR,Chen XH,Kong LR,Xu L,Ruan CC,Gao PJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Sep 06 00:00:00 EDT 2021

PDGF-D activation by macrophage-derived uPA promotes AngII-induced cardiac remodeling in obese mice.

The Journal of experimental medicine

Cheng YW,Zhang ZB,Lan BD,Lin JR,Chen XH,Kong LR,Xu L,Ruan CC,Gao PJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Sep 06 00:00:00 EDT 2021

A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis.

Biomaterials

Keum H,Kim D,Kim J,Kim TW,Whang CH,Jung W,Jon S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun Aug 01 00:00:00 EDT 2021

A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis.

Biomaterials

Keum H,Kim D,Kim J,Kim TW,Whang CH,Jung W,Jon S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun Aug 01 00:00:00 EDT 2021

Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.

The EMBO journal

Wieghofer P,Hagemeyer N,Sankowski R,Schlecht A,Staszewski O,Amann L,Gruber M,Koch J,Hausmann A,Zhang P,Boneva S,Masuda T,Hilgendorf I,Goldmann T,Böttcher C,Priller J,Rossi FM,Lange C,Prinz M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Mar 15 00:00:00 EDT 2021

Tumor- and osteoclast-derived NRP2 in prostate cancer bone metastases.

Bone research

Polavaram NS,Dutta S,Islam R,Bag AK,Roy S,Poitz D,Karnes J,Hofbauer LC,Kohli M,Costello BA,Jimenez R,Batra SK,Teply BA,Muders MH,Datta K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri May 14 00:00:00 EDT 2021

Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.

Basic research in cardiology

Frenis K,Helmstädter J,Ruan Y,Schramm E,Kalinovic S,Kröller-Schön S,Bayo Jimenez MT,Hahad O,Oelze M,Jiang S,Wenzel P,Sommer CJ,Frauenknecht KBM,Waisman A,Gericke A,Daiber A,Münzel T,Steven S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Apr 30 00:00:00 EDT 2021

Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice.

Cell death and differentiation

Jiang Y,Tang Y,Hoover C,Kondo Y,Huang D,Restagno D,Shao B,Gao L,Michael McDaniel J,Zhou M,Silasi-Mansat R,McGee S,Jiang M,Bai X,Lupu F,Ruan C,Marth JD,Wu D,Han Y,Xia L

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Mon Nov 01 00:00:00 EDT 2021

Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice.

Cell death and differentiation

Jiang Y,Tang Y,Hoover C,Kondo Y,Huang D,Restagno D,Shao B,Gao L,Michael McDaniel J,Zhou M,Silasi-Mansat R,McGee S,Jiang M,Bai X,Lupu F,Ruan C,Marth JD,Wu D,Han Y,Xia L

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Mon Nov 01 00:00:00 EDT 2021

TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury.

British journal of pharmacology

Rosa JM,Farré-Alins V,Ortega MC,Navarrete M,Lopez-Rodriguez AB,Palomino-Antolín A,Fernández-López E,Vila-Del Sol V,Decouty C,Narros-Fernández P,Clemente D,Egea J

48-4801-82 was used in Flow Cytometry to demonstrate that TLR4-mediated signalling, most probably through microglia and/or infiltrated monocyte-astrocyte communication, plays a crucial role in the TBI pathophysiology and that its inhibition prevents synaptic loss and BBB damage accelerating tissue recovery/repair, which might represent a therapeutic potential in CNS injuries and disorders.

Wed Sep 01 00:00:00 EDT 2021

Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.

Diabetes

Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2021

Interleukin 6 regulates the expression of programmed cell death ligand 1 in thyroid cancer.

Cancer science

Zhang GQ,Jiao Q,Shen CT,Song HJ,Zhang HZ,Qiu ZL,Luo QY

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

Potential functions of embryonic cardiac macrophages in angiogenesis, lymphangiogenesis and extracellular matrix remodeling.

Histochemistry and cell biology

Gula G,Rumiński S,Niderla-Bielińska J,Jasińska A,Kiernozek E,Jankowska-Steifer E,Flaht-Zabost A,Ratajska A

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Jan 01 00:00:00 EST 2021

Assessment of ¹⁸F-PBR-111 in the Cuprizone Mouse Model of Multiple Sclerosis.

Diagnostics (Basel, Switzerland)

Jewells VL,Yuan H,Merrill JR,Frank JE,Patel A,Cohen SM,Giglio B,Feinberg NN,Matsushima GK,Li Z

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Tue Apr 27 00:00:00 EDT 2021

Assessment of ¹⁸F-PBR-111 in the Cuprizone Mouse Model of Multiple Sclerosis.

Diagnostics (Basel, Switzerland)

Jewells VL,Yuan H,Merrill JR,Frank JE,Patel A,Cohen SM,Giglio B,Feinberg NN,Matsushima GK,Li Z

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Tue Apr 27 00:00:00 EDT 2021

IL-19 Contributes to the Development of Nonalcoholic Steatohepatitis by Altering Lipid Metabolism.

Cells

Azuma YT,Fujita T,Izawa T,Hirota K,Nishiyama K,Ikegami A,Aoyama T,Ike M,Ushikai Y,Kuwamura M,Fujii H,Tsuneyama K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Dec 13 00:00:00 EST 2021

Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis.

Scientific reports

Cai C,Zeng D,Gao Q,Ma L,Zeng B,Zhou Y,Wang H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Mon Jun 28 00:00:00 EDT 2021

Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.

Biology

Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (Frozen)

Thu May 27 00:00:00 EDT 2021

Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models.

Cellular and molecular gastroenterology and hepatology

Kusakabe J,Hata K,Miyauchi H,Tajima T,Wang Y,Tamaki I,Kawasoe J,Okamura Y,Zhao X,Okamoto T,Tsuruyama T,Uemoto S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Mar 08 00:00:00 EST 2022

Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment.

eLife

Shan Z,Li L,Atkins CL,Wang M,Wen Y,Jeong J,Moreno NF,Feng D,Gui X,Zhang N,Lee CG,Elias JA,Lee WM,Gao B,Lam FW,An Z,Ju C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Thu Jun 10 00:00:00 EDT 2021

Thymopentin treatment of murine premature ovarian failure via attenuation of immune cell activity and promotion of the BMP4/Smad9 signalling pathway.

International journal of medical sciences

Zhu X,Liu J,Pan H,Geng Z,Huang W,Liu T,Zhang B

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Tue Mar 15 00:00:00 EDT 2022

Treatment with the Probiotic Product Aviguard^® Alleviates Inflammatory Responses during Campylobacter jejuni-Induced Acute Enterocolitis in Mice.

International journal of molecular sciences

Heimesaat MM,Weschka D,Mousavi S,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Jun 22 00:00:00 EDT 2021

Peroral Clove Essential Oil Treatment Ameliorates Acute Campylobacteriosis-Results from a Preclinical Murine Intervention Study.

Microorganisms

Bereswill S,Mousavi S,Weschka D,Buczkowski A,Schmidt S,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Mar 31 00:00:00 EDT 2021

Nonalcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet.

Cellular and molecular gastroenterology and hepatology

Ganguly S,Muench GA,Shang L,Rosenthal SB,Rahman G,Wang R,Wang Y,Kwon HC,Diomino AM,Kisseleva T,Soorosh P,Hosseini M,Knight R,Schnabl B,Brenner DA,Dhar D

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Mar 22 00:00:00 EDT 2022

Disease-Alleviating Effects of Peroral Activated Charcoal Treatment in Acute Murine Campylobacteriosis.

Microorganisms

Bereswill S,Mousavi S,Weschka D,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Jun 30 00:00:00 EDT 2021

Evidence of a Myenteric Plexus Barrier and Its Macrophage-Dependent Degradation During Murine Colitis: Implications in Enteric Neuroinflammation.

Cellular and molecular gastroenterology and hepatology

Dora D,Ferenczi S,Stavely R,Toth VE,Varga ZV,Kovacs T,Bodi I,Hotta R,Kovacs KJ,Goldstein AM,Nagy N

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Mon Mar 28 00:00:00 EDT 2022

Evidence of a Myenteric Plexus Barrier and Its Macrophage-Dependent Degradation During Murine Colitis: Implications in Enteric Neuroinflammation.

Cellular and molecular gastroenterology and hepatology

Dora D,Ferenczi S,Stavely R,Toth VE,Varga ZV,Kovacs T,Bodi I,Hotta R,Kovacs KJ,Goldstein AM,Nagy N

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Mon Mar 28 00:00:00 EDT 2022

MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model.

The Journal of clinical investigation

Tilstam PV,Schulte W,Holowka T,Kim BS,Nouws J,Sauler M,Piecychna M,Pantouris G,Lolis E,Leng L,Bernhagen J,Fingerle-Rowson G,Bucala R

48-4801-82 was used in flow cytometry to study Mif-/- and Mif-2-/- mice to polymicrobial sepsis and observed a survival benefit with Mif but not Mif-2 deficiency.

Wed Dec 01 00:00:00 EST 2021

Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma.

Scientific reports

Mittal A,Wang M,Vidyarthi A,Yanez D,Pizzurro G,Thakral D,Tracy E,Colegio OR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon May 24 00:00:00 EDT 2021

Comprehensive analysis of liver macrophage composition by flow cytometry and immunofluorescence in murine NASH.

STAR protocols

Daemen S,Chan MM,Schilling JD

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Jun 18 00:00:00 EDT 2021

Generation and utilization of a HEK-293T murine GM-CSF expressing cell line.

PloS one

Robinson EK,Covarrubias S,Zhou S,Carpenter S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Sep 15 00:00:00 EDT 2021

Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway.

International journal of molecular sciences

Chow SKH,Cui C,Cheng KYK,Chim YN,Wang J,Wong CHW,Ng KW,Wong RMY,Cheung WH

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Fri Aug 13 00:00:00 EDT 2021

Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.

Journal of neuroinflammation

Oladiran O,Shi XQ,Yang M,Fournier S,Zhang J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Mar 22 00:00:00 EDT 2021

Ly6c^hi Infiltrating Macrophages Promote Cyst Progression in Injured Conditional Ift88 Mice.

Kidney360

Aloria EJG,Song CJ,Li Z,Croyle MJ,Mrug M,Zimmerman KA,Yoder BK

48-4801-82 was used in Immunohistochemistry (Frozen) to study how Ccr2-dependent, Ly6chi infiltrating macrophages promote cyst progression in the injury-accelerated, adult-induced, conditional Ift88 model of cystic disease.

Thu Jun 24 00:00:00 EDT 2021

STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.

Cellular and molecular gastroenterology and hepatology

Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Jan 24 00:00:00 EST 2022

CX3CR1 But Not CCR2 Expression Is Required for the Development of Autoimmune Peripheral Neuropathy in Mice.

Frontiers in immunology

Oladiran O,Shi XQ,Fournier S,Zhang J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Dec 21 00:00:00 EST 2021

Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.

Frontiers in immunology

Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Feb 10 00:00:00 EST 2022

Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics.

eLife

Serrano-Lopez J,Hegde S,Kumar S,Serrano J,Fang J,Wellendorf AM,Roche PA,Rangel Y,Carrington LJ,Geiger H,Grimes HL,Luther S,Maillard I,Sanchez-Garcia J,Starczynowski DT,Cancelas JA

48-4801-82 was used in Flow cytometry/Cell sorting to demonstrate that acute systemic inflammation induces the emergent activation of a previously unrecognized system of rapid migration of granulocyte-macrophage progenitors and committed macrophage-dendritic progenitors, but not other progenitors or stem cells, from bone marrow (BM) to regional lymphatic capillaries.

Thu Apr 08 00:00:00 EDT 2021

Characterisation of Macrophage Polarisation in Mice Infected with Ninoa Strain of Trypanosoma cruzi.

Pathogens (Basel, Switzerland)

Medina-Buelvas DM,Rodríguez-Sosa M,Vega L

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sat Nov 06 00:00:00 EDT 2021

Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver.

Immunity

Remmerie A,Martens L,Thoné T,Castoldi A,Seurinck R,Pavie B,Roels J,Vanneste B,De Prijck S,Vanhockerhout M,Binte Abdul Latib M,Devisscher L,Hoorens A,Bonnardel J,Vandamme N,Kremer A,Borghgraef P,Van Vlierberghe H,Lippens S,Pearce E,Saeys Y,Scott CL

48-4801 was used in Flow cytometry/Cell sorting to highlight considerable heterogeneity within the macrophage pool and suggest a need for more specific macrophage targeting strategies in metabolic-associated fatty liver disease (MAFLD).

Tue Sep 15 00:00:00 EDT 2020

Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair.

Cell stem cell

Shook BA,Wasko RR,Mano O,Rutenberg-Schoenberg M,Rudolph MC,Zirak B,Rivera-Gonzalez GC,López-Giráldez F,Zarini S,Rezza A,Clark DA,Rendl M,Rosenblum MD,Gerstein MB,Horsley V

48-4801-82 was used in Flow Cytometry to identify an essential role for adipocyte lipolysis in regulating inflammation and repair after injury in skin.

Thu Jun 04 00:00:00 EDT 2020

Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.

Nano-micro letters

Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sat Nov 21 00:00:00 EST 2020

Chronic mTOR activation induces a degradative smooth muscle cell phenotype.

The Journal of clinical investigation

Li G,Wang M,Caulk AW,Cilfone NA,Gujja S,Qin L,Chen PY,Chen Z,Yousef S,Jiao Y,He C,Jiang B,Korneva A,Bersi MR,Wang G,Liu X,Mehta S,Geirsson A,Gulcher JR,Chittenden TW,Simons M,Humphrey JD,Tellides G

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Mon Mar 02 00:00:00 EST 2020

Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.

The Journal of clinical investigation

Khiew SH,Jain D,Chen J,Yang J,Yin D,Young JS,Dent A,Sciammas R,Alegre ML,Chong AS

48-4801 was used in Flow cytometry/Cell sorting to showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies., by using a murine model of heart tolerance.

Wed Jul 01 00:00:00 EDT 2020

Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage-myofibroblast transition.

Proceedings of the National Academy of Sciences of the United States of America

Tang PM,Zhang YY,Xiao J,Tang PC,Chung JY,Li J,Xue VW,Huang XR,Chong CC,Ng CF,Lee TL,To KF,Nikolic-Paterson DJ,Lan HY

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Tue Aug 25 00:00:00 EDT 2020

Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage-myofibroblast transition.

Proceedings of the National Academy of Sciences of the United States of America

Tang PM,Zhang YY,Xiao J,Tang PC,Chung JY,Li J,Xue VW,Huang XR,Chong CC,Ng CF,Lee TL,To KF,Nikolic-Paterson DJ,Lan HY

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Tue Aug 25 00:00:00 EDT 2020

Periodontal inflammation recruits distant metastatic breast cancer cells by increasing myeloid-derived suppressor cells.

Oncogene

Cheng R,Billet S,Liu C,Haldar S,Choudhury D,Tripathi M,Hav M,Merchant A,Hu T,Huang H,Zhou H,Bhowmick NA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sat Feb 01 00:00:00 EST 2020

Absence of Bsep/Abcb11 attenuates MCD diet-induced hepatic steatosis but aggravates inflammation in mice.

Liver international : official journal of the International Association for the Study of the Liver

Fuchs CD,Krivanec S,Steinacher D,Mlitz V,Wahlström A,Stahlman M,Claudel T,Scharnagl H,Stojakovic T,Marschall HU,Trauner M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Jun 01 00:00:00 EDT 2020

Spatial proteomics revealed a CX₃CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder.

Mucosal immunology

Bottek J,Soun C,Lill JK,Dixit A,Thiebes S,Beerlage AL,Horstmann M,Urbanek A,Heuer H,Uszkoreit J,Eisenacher M,Bracht T,Sitek B,Hoffmann F,Vijitha N,von Eggeling F,Engel DR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Jul 01 00:00:00 EDT 2020

Spatial proteomics revealed a CX₃CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder.

Mucosal immunology

Bottek J,Soun C,Lill JK,Dixit A,Thiebes S,Beerlage AL,Horstmann M,Urbanek A,Heuer H,Uszkoreit J,Eisenacher M,Bracht T,Sitek B,Hoffmann F,Vijitha N,von Eggeling F,Engel DR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Jul 01 00:00:00 EDT 2020

Macrophage GIT1 Contributes to Bone Regeneration by Regulating Inflammatory Responses in an ERK/NRF2-Dependent Way.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Zhao SJ,Liu H,Chen J,Qian DF,Kong FQ,Jie J,Yin GY,Li QQ,Fan J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Neonatal Heart Responds to Pressure Overload With Differential Alterations in Various Cardiomyocyte Maturation Programs That Accommodate Simultaneous Hypertrophy and Hyperplasia.

Frontiers in cell and developmental biology

Ding X,Wang S,Wang Y,Yang J,Bao N,Liu J,Zhang Z

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Dec 18 00:00:00 EST 2020

Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3β/β-catenin pathway.

Theranostics

Zhao SJ,Kong FQ,Jie J,Li Q,Liu H,Xu AD,Yang YQ,Jiang B,Wang DD,Zhou ZQ,Tang PY,Chen J,Wang Q,Zhou Z,Chen Q,Yin GY,Zhang HW,Fan J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (PFA fixed)

Fri Apr 02 00:00:00 EDT 2021

Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3β/β-catenin pathway.

Theranostics

Zhao SJ,Kong FQ,Jie J,Li Q,Liu H,Xu AD,Yang YQ,Jiang B,Wang DD,Zhou ZQ,Tang PY,Chen J,Wang Q,Zhou Z,Chen Q,Yin GY,Zhang HW,Fan J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (PFA fixed)

Fri Apr 02 00:00:00 EDT 2021

Orf Virus IL-10 and VEGF-E Act Synergistically to Enhance Healing of Cutaneous Wounds in Mice.

Journal of clinical medicine

Wise LM,Stuart GS,Jones NC,Fleming SB,Mercer AA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Sat Apr 11 00:00:00 EDT 2020

Nanochannel-Based Poration Drives Benign and Effective Nonviral Gene Delivery to Peripheral Nerve Tissue.

Advanced biosystems

Moore JT,Wier CG,Lemmerman LR,Ortega-Pineda L,Dodd DJ,Lawrence WR,Duarte-Sanmiguel S,Dathathreya K,Diaz-Starokozheva L,Harris HN,Sen CK,Valerio IL,Higuita-Castro N,Arnold WD,Kolb SJ,Gallego-Perez D

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Sun Nov 01 00:00:00 EDT 2020

Preclinical Evaluation of Oral Urolithin-A for the Treatment of Acute Campylobacteriosis in Campylobacter jejuni Infected Microbiota-Depleted IL-10^-/- Mice.

Pathogens (Basel, Switzerland)

Mousavi S,Weschka D,Bereswill S,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Dec 23 00:00:00 EST 2020

Immune-modulatory Properties of the Octapeptide NAP in Campylobacter jejuni Infected Mice Suffering from Acute Enterocolitis.

Microorganisms

Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Giladi E,Bereswill S,Gozes I

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue May 26 00:00:00 EDT 2020

Inhibition of Yes-Associated Protein by Verteporfin Ameliorates Unilateral Ureteral Obstruction-Induced Renal Tubulointerstitial Inflammation and Fibrosis.

International journal of molecular sciences

Jin J,Wang T,Park W,Li W,Kim W,Park SK,Kang KP

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sat Oct 31 00:00:00 EDT 2020

Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury.

Journal of neuroinflammation

Kong FQ,Zhao SJ,Sun P,Liu H,Jie J,Xu T,Xu AD,Yang YQ,Zhu Y,Chen J,Zhou Z,Qian DF,Gu CJ,Chen Q,Yin GY,Zhang HW,Fan J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Mon Feb 17 00:00:00 EST 2020

Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury.

Journal of neuroinflammation

Kong FQ,Zhao SJ,Sun P,Liu H,Jie J,Xu T,Xu AD,Yang YQ,Zhu Y,Chen J,Zhou Z,Qian DF,Gu CJ,Chen Q,Yin GY,Zhang HW,Fan J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Mon Feb 17 00:00:00 EST 2020

Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1.

Nature metabolism

Brett JO,Arjona M,Ikeda M,Quarta M,de Morrée A,Egner IM,Perandini LA,Ishak HD,Goshayeshi A,Benjamin DI,Both P,Rodríguez-Mateo C,Betley MJ,Wyss-Coray T,Rando TA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Apr 01 00:00:00 EDT 2020

Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype.

International journal of molecular sciences

Pavlović N,Kopsida M,Gerwins P,Heindryckx F

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sat Oct 31 00:00:00 EDT 2020

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.

Cell reports

Blagih J,Zani F,Chakravarty P,Hennequart M,Pilley S,Hobor S,Hock AK,Walton JB,Morton JP,Gronroos E,Mason S,Yang M,McNeish I,Swanton C,Blyth K,Vousden KH

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Jan 14 00:00:00 EST 2020

Modulated Electro-Hyperthermia-Induced Tumor Damage Mechanisms Revealed in Cancer Models.

International journal of molecular sciences

Krenacs T,Meggyeshazi N,Forika G,Kiss E,Hamar P,Szekely T,Vancsik T

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sat Aug 29 00:00:00 EDT 2020

Prodrug-Loaded Zirconium Carbide Nanosheets as a Novel Biophotonic Nanoplatform for Effective Treatment of Cancer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Liu Q,Xie Z,Qiu M,Shim I,Yang Y,Xie S,Yang Q,Wang D,Chen S,Fan T,Ding B,Guo Z,Adah D,Yao X,Zhang Y,Wu H,Wu Z,Wei C,Wang H,Kim HS,Zou Q,Yan Q,Cai Z,Kim JS,Liu LP,Zhang H,Cao Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Dec 01 00:00:00 EST 2020

Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease.

Kidney360

Zimmerman KA,Huang J,He L,Revell DZ,Li Z,Hsu JS,Fitzgibbon WR,Hazard ES,Hardiman G,Mrug M,Bell PD,Yoder BK,Saigusa T

48-4801 was used in Flow cytometry/Cell sorting to suggest that Irf5 promotes inflammatory cytokine production in resident macrophages resulting in accelerated cystogenesis.

Sun Mar 01 00:00:00 EST 2020

Differential Activation of Macrophages Based on Their Environment in Advanced Age.

Chonnam medical journal

Lee DY,Lim JS,Cho KA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model.

Scientific reports

Bonfanti AP,Barreto N,Munhoz J,Caballero M,Cordeiro G,Rocha-E-Silva T,Sutti R,Moura F,Brunetto S,Ramos CD,Thomé R,Verinaud L,Rapôso C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Apr 03 00:00:00 EDT 2020

High-salt diet decreases mechanical thresholds in mice that is mediated by a CCR2-dependent mechanism.

Journal of neuroinflammation

Fan A,Oladiran O,Shi XQ,Zhang J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jun 09 00:00:00 EDT 2020

Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.

STAR protocols

Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Jun 19 00:00:00 EDT 2020

Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli.

ImmunoHorizons

Schilke RM,Blackburn CMR,Rao S,Krzywanski DM,Finck BN,Woolard MD

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Oct 19 00:00:00 EDT 2020

Obesogenic Memory Maintains Adipose Tissue Inflammation and Insulin Resistance.

Immunometabolism

Blaszczak AM,Bernier M,Wright VP,Gebhardt G,Anandani K,Liu J,Jalilvand A,Bergin S,Wysocki V,Somogyi A,Bradley D,Hsueh WA

48-4801 was used in Flow cytometry/Cell sorting to determine if weight loss following obesity would correct AT inflammation and systemic metabolism.

Sat Apr 16 00:00:00 EDT 2022

Host deficiency in ephrin-A1 inhibits breast cancer metastasis.

F1000Research

Shiuan E,Inala A,Wang S,Song W,Youngblood V,Chen J,Brantley-Sieders DM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2021

MFG-E8 accelerates wound healing in diabetes by regulating "NLRP3 inflammasome-neutrophil extracellular traps" axis.

Cell death discovery

Huang W,Jiao J,Liu J,Huang M,Hu Y,Ran W,Yan L,Xiong Y,Li M,Quan Z,Rao Y,Chen J,Huang Y,Zhang D

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Sep 26 00:00:00 EDT 2023

Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration.

Journal of neuroinflammation

Little K,Llorián-Salvador M,Tang M,Du X,Marry S,Chen M,Xu H

48-4801 was used in Flow cytometry/Cell sorting to understand how infiltrating macrophages and complement proteins may contribute to macular fibrosis.

Wed Nov 25 00:00:00 EST 2020

Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer.

Journal of hematology & oncology

Lu CS,Shiau AL,Su BH,Hsu TS,Wang CT,Su YC,Tsai MS,Feng YH,Tseng YL,Yen YT,Wu CL,Shieh GS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2020

Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells.

JCI insight

Hadas R,Gershon E,Cohen A,Atrakchi O,Lazar S,Golani O,Dassa B,Elbaz M,Cohen G,Eilam R,Dekel N,Neeman M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2020

Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.

eLife

Kim EH,Woodruff MC,Grigoryan L,Maier B,Lee SH,Mandal P,Cortese M,Natrajan MS,Ravindran R,Ma H,Merad M,Gitlin AD,Mocarski ES,Jacob J,Pulendran B

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jun 09 00:00:00 EDT 2020

Inhibition of Fatty Acid-Binding Protein 4 Attenuated Kidney Fibrosis by Mediating Macrophage-to-Myofibroblast Transition.

Frontiers in immunology

Feng Y,Guo F,Xia Z,Liu J,Mai H,Liang Y,Zhu G,Li Y,Bai L,Li L,Huang R,Shi M,Ma L,Fu P

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Jun 03 00:00:00 EDT 2021

Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.

Cells

Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jul 07 00:00:00 EDT 2020

Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression.

Nature communications

Yu L,Zhang B,Deochand D,Sacta MA,Coppo M,Shang Y,Guo Z,Zeng X,Rollins DA,Tharmalingam B,Li R,Chinenov Y,Rogatsky I,Hu X

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri May 08 00:00:00 EDT 2020

Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.

Cell & bioscience

Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Apr 14 00:00:00 EDT 2022

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.

Nature

Escolano A,Gristick HB,Abernathy ME,Merkenschlager J,Gautam R,Oliveira TY,Pai J,West AP,Barnes CO,Cohen AA,Wang H,Golijanin J,Yost D,Keeffe JR,Wang Z,Zhao P,Yao KH,Bauer J,Nogueira L,Gao H,Voll AV,Montefiori DC,Seaman MS,Gazumyan A,Silva M,McGuire AT,Stamatatos L,Irvine DJ,Wells L,Martin MA,Bjorkman PJ,Nussenzweig MC

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sat Jun 01 00:00:00 EDT 2019

GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.

Cancer cell

Mondragón L,Mhaidly R,De Donatis GM,Tosolini M,Dao P,Martin AR,Pons C,Chiche J,Jacquin M,Imbert V,Proïcs E,Boyer L,Doye A,Luciano F,Neels JG,Coutant F,Fabien N,Sormani L,Rubio-Patiño C,Bossowski JP,Muller F,Marchetti S,Villa E,Peyron JF,Gaulard P,Lemonnier F,Asnafi V,Genestier L,Benhida R,Fournié JJ,Passeron T,Ricci JE,Verhoeyen E

48-4801-82 was used in Flow Cytometry to suggest the therapeutic potential of targeting NF-κB signaling in AITL and provide a model for future AITL therapeutic investigations.

Mon Sep 16 00:00:00 EDT 2019

NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD.

Hepatology (Baltimore, Md.)

Ohashi K,Wang Z,Yang YM,Billet S,Tu W,Pimienta M,Cassel SL,Pandol SJ,Lu SC,Sutterwala FS,Bhowmick N,Seki E

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Nov 01 00:00:00 EDT 2019

Kynurenine 3-monooxygenase is a critical regulator of renal ischemia-reperfusion injury.

Experimental & molecular medicine

Zheng X,Zhang A,Binnie M,McGuire K,Webster SP,Hughes J,Howie SEM,Mole DJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Feb 13 00:00:00 EST 2019

Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis.

Purinergic signalling

Rothweiler S,Feldbrügge L,Jiang ZG,Csizmadia E,Longhi MS,Vaid K,Enjyoji K,Popov YV,Robson SC

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun Sep 01 00:00:00 EDT 2019

Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.

Anti-cancer drugs

Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours.

Nature communications

Fu R,Han CF,Ni T,Di L,Liu LJ,Lv WC,Bi YR,Jiang N,He Y,Li HM,Wang S,Xie H,Chen BA,Wang XS,Weiss SJ,Lu T,Guo QL,Wu ZQ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Jul 19 00:00:00 EDT 2019

A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours.

Nature communications

Fu R,Han CF,Ni T,Di L,Liu LJ,Lv WC,Bi YR,Jiang N,He Y,Li HM,Wang S,Xie H,Chen BA,Wang XS,Weiss SJ,Lu T,Guo QL,Wu ZQ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Jul 19 00:00:00 EDT 2019

Epithelial innate immunity mediates tubular cell senescence after kidney injury.

JCI insight

Jin H,Zhang Y,Ding Q,Wang SS,Rastogi P,Dai DF,Lu D,Purvis M,Cao C,Wang A,Liu D,Ren C,Elhadi S,Hu MC,Chai Y,Zepeda-Orozco D,Campisi J,Attanasio M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Thu Jan 24 00:00:00 EST 2019

Epithelial innate immunity mediates tubular cell senescence after kidney injury.

JCI insight

Jin H,Zhang Y,Ding Q,Wang SS,Rastogi P,Dai DF,Lu D,Purvis M,Cao C,Wang A,Liu D,Ren C,Elhadi S,Hu MC,Chai Y,Zepeda-Orozco D,Campisi J,Attanasio M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Thu Jan 24 00:00:00 EST 2019

Murine Fecal Microbiota Transplantation Alleviates Intestinal and Systemic Immune Responses in Campylobacter jejuni Infected Mice Harboring a Human Gut Microbiota.

Frontiers in immunology

Heimesaat MM,Mrazek K,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (Paraffin)

Mon Oct 26 00:00:00 EDT 2020

Murine Fecal Microbiota Transplantation Alleviates Intestinal and Systemic Immune Responses in Campylobacter jejuni Infected Mice Harboring a Human Gut Microbiota.

Frontiers in immunology

Heimesaat MM,Mrazek K,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (Paraffin)

Mon Oct 26 00:00:00 EDT 2020

Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.

PLoS genetics

Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A.

Nature communications

Körner A,Schlegel M,Kaussen T,Gudernatsch V,Hansmann G,Schumacher T,Giera M,Mirakaj V

48-4801-82 was used in Flow Cytometry to show that the adrenergic nerves of sympathetic nervous system orchestrate inflammation resolution and regenerative programs by modulating repulsive guidance molecule A (RGM-A).

Thu Feb 07 00:00:00 EST 2019

Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.

Cellular and molecular gastroenterology and hepatology

Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H

48-4801 was used in Flow cytometry/Cell sorting to demonstrate that the clinical use of blocking CCL5 may induce other chemokine signals such as CXCL1-CXCR2 to induce further enhanced hepatic infiltration of neutrophils.

Tue Jun 04 00:00:00 EDT 2019

A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions.

Nature communications

MohanKumar K,Namachivayam K,Song T,Jake Cha B,Slate A,Hendrickson JE,Pan H,Wickline SA,Oh JY,Patel RP,He L,Torres BA,Maheshwari A

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Aug 02 00:00:00 EDT 2019

A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions.

Nature communications

MohanKumar K,Namachivayam K,Song T,Jake Cha B,Slate A,Hendrickson JE,Pan H,Wickline SA,Oh JY,Patel RP,He L,Torres BA,Maheshwari A

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Aug 02 00:00:00 EDT 2019

Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila.

Cell reports

Zhang R,Earnest JT,Kim AS,Winkler ES,Desai P,Adams LJ,Hu G,Bullock C,Gold B,Cherry S,Diamond MS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Sep 03 00:00:00 EDT 2019

Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer.

Cell reports

Di Mitri D,Mirenda M,Vasilevska J,Calcinotto A,Delaleu N,Revandkar A,Gil V,Boysen G,Losa M,Mosole S,Pasquini E,D'Antuono R,Masetti M,Zagato E,Chiorino G,Ostano P,Rinaldi A,Gnetti L,Graupera M,Martins Figueiredo Fonseca AR,Pereira Mestre R,Waugh D,Barry S,De Bono J,Alimonti A

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Aug 20 00:00:00 EDT 2019

MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.

Journal for immunotherapy of cancer

Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Nov 28 00:00:00 EST 2019

Anti-Bacterial Effect of CpG-DNA Involves Enhancement of the Complement Systems.

International journal of molecular sciences

Kim TH,Park J,Kim D,Gautam A,Akauliya M,Kim J,Lee H,Park S,Lee Y,Kwon HJ

48-4801-82 was used in Flow Cytometry to suggest that CpG-DNA enhances the anti-bacterial activity of the immune system by augmenting the levels of complement systems after E. coli K1 infection and triggering other factors as well.

Wed Jul 10 00:00:00 EDT 2019

Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5⁺ Stem Cells via Inhibition of Wnt and Notch Signaling.

Cellular and molecular gastroenterology and hepatology

Zha JM,Li HS,Lin Q,Kuo WT,Jiang ZH,Tsai PY,Ding N,Wu J,Xu SF,Wang YT,Pan J,Zhou XM,Chen K,Tao M,Odenwald MA,Tamura A,Tsukita S,Turner JR,He WQ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon May 06 00:00:00 EDT 2019

Peritoneal Cells Mediate Immune Responses and Cross-Protection Against Influenza A Virus.

Frontiers in immunology

Gautam A,Park BK,Kim TH,Akauliya M,Kim D,Maharjan S,Park J,Kim J,Lee H,Park MS,Lee Y,Kwon HJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Aug 17 00:00:00 EDT 2020

Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation.

Cell reports

Ciecko AE,Foda B,Barr JY,Ramanathan S,Atkinson MA,Serreze DV,Geurts AM,Lieberman SM,Chen YG

48-4801-82 was used in Flow Cytometry to reveal that IL-27 contributes to autoimmunity in NOD mice through multiple mechanisms and provides substantial evidence to support its pathogenic role in human T1D.

Tue Dec 03 00:00:00 EST 2019

Therapeutic ultrasound attenuates DSS-induced colitis through the cholinergic anti-inflammatory pathway.

EBioMedicine

Nunes NS,Chandran P,Sundby M,Visioli F,da Costa Gonçalves F,Burks SR,Paz AH,Frank JA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Jul 01 00:00:00 EDT 2019

Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity.

Nature metabolism

Seo JB,Riopel M,Cabrales P,Huh JY,Bandyopadhyay GK,Andreyev AY,Murphy AN,Beeman SC,Smith GI,Klein S,Lee YS,Olefsky JM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2019

A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Critical Illness.

Frontiers in medicine

Hasan S,Johnson MC,Kini AR,Baldea AJ,Muthumalaiappan K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Nov 03 00:00:00 EST 2020

Bone-derived Nestin-positive mesenchymal stem cells improve cardiac function via recruiting cardiac endothelial cells after myocardial infarction.

Stem cell research & therapy

Lu D,Liao Y,Zhu SH,Chen QC,Xie DM,Liao JJ,Feng X,Jiang MH,He W

48-4801 was used in Flow cytometry/Cell sorting to show that Nestin is a useful marker for the identification of functional BMSCs and indicate that Nestin+ BMSCs could be a better therapeutic candidate for cardiac repair.

Sat Apr 27 00:00:00 EDT 2019

Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.

Nature communications

Kusano T,Ehirchiou D,Matsumura T,Chobaz V,Nasi S,Castelblanco M,So A,Lavanchy C,Acha-Orbea H,Nishino T,Okamoto K,Busso N

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Oct 28 00:00:00 EDT 2019

TREM2 regulates obesity-induced insulin resistance via adipose tissue remodeling in mice of high-fat feeding.

Journal of translational medicine

Liu C,Li P,Li H,Wang S,Ding L,Wang H,Ye H,Jin Y,Hou J,Fang X,Shu Q

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Sep 02 00:00:00 EDT 2019

Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.

Nature communications

Kurelac I,Iommarini L,Vatrinet R,Amato LB,De Luise M,Leone G,Girolimetti G,Umesh Ganesh N,Bridgeman VL,Ombrato L,Columbaro M,Ragazzi M,Gibellini L,Sollazzo M,Feichtinger RG,Vidali S,Baldassarre M,Foriel S,Vidone M,Cossarizza A,Grifoni D,Kofler B,Malanchi I,Porcelli AM,Gasparre G

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Feb 22 00:00:00 EST 2019

Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes.

EBioMedicine

Bai J,Gao Y,Chen L,Yin Q,Lou F,Wang Z,Xu Z,Zhou H,Li Q,Cai W,Sun Y,Niu L,Wang H,Wei Z,Lu S,Zhou A,Zhang J,Wang H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Jan 01 00:00:00 EST 2019

A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma.

Journal of clinical medicine

Kurelac I,Abarrategi A,Ragazzi M,Iommarini L,Umesh Ganesh N,Snoeks T,Bonnet D,Porcelli AM,Malanchi I,Gasparre G

48-4801 was used in Flow cytometry/Cell sorting to characterize the tumour microenvironment of mitochondrial complex I deficient tumors in a model that represents osteosarcoma development.

Wed Dec 11 00:00:00 EST 2019

Vitamin D in Acute Campylobacteriosis-Results From an Intervention Study Applying a Clinical Campylobacter jejuni Induced Enterocolitis Model.

Frontiers in immunology

Mousavi S,Lobo de Sá FD,Schulzke JD,Bücker R,Bereswill S,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Nov 09 00:00:00 EST 2020

miR-21 Expression Determines the Early Vaccine Immunity Induced by LdCen^-/- Immunization.

Frontiers in immunology

Gannavaram S,Bhattacharya P,Siddiqui A,Ismail N,Madhavan S,Nakhasi HL

48-4801-82 was used in Flow Cytometry to demonstrate that LdCen -/- infection suppresses miR-21 expression, enables IL12 mediated induction of adaptive immunity including proliferation of antigen experienced CD4+ T cells and development of a Th1 immunity, and suggest that miR-21 could be an important biomarker for LdCen -/- vaccine immunity in human clinical trials.

Mon Oct 26 00:00:00 EDT 2020

The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response.

Scientific reports

Tellez Freitas CM,Burrell HR,Valdoz JC,Hamblin GJ,Raymond CM,Cox TD,Johnson DK,Andersen JL,Weber KS,Bridgewater LC

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Jan 30 00:00:00 EST 2019

Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection.

Cell death discovery

Wang N,Yang X,Sun J,Sun Z,Ma Q,Wang Z,Chen Z,Wang Z,Hu F,Wang H,Zhou L,Zhang M,Xu J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Sep 30 00:00:00 EDT 2020

Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis.

Cell death & disease

Farooq M,Filliol A,Simoes Eugénio M,Piquet-Pellorce C,Dion S,Raguenes-Nicol C,Jan A,Dimanche-Boitrel MT,Le Seyec J,Samson M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Jan 08 00:00:00 EST 2019

Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity.

Immunity

Sakai M,Troutman TD,Seidman JS,Ouyang Z,Spann NJ,Abe Y,Ego KM,Bruni CM,Deng Z,Schlachetzki JCM,Nott A,Bennett H,Chang J,Vu BT,Pasillas MP,Link VM,Texari L,Heinz S,Thompson BM,McDonald JG,Geissmann F,Glass CK

48-4801-82 was used in Flow cytometry/Cell sorting to provide a framework for understanding how macrophage progenitor cells acquire tissue-specific phenotypes.

Tue Oct 15 00:00:00 EDT 2019

Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells.

Nature

Kim HS,Tan Y,Ma W,Merkurjev D,Destici E,Ma Q,Suter T,Ohgi K,Friedman M,Skowronska-Krawczyk D,Rosenfeld MG

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Sun Apr 01 00:00:00 EDT 2018

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.

Nature

Morioka S,Perry JSA,Raymond MH,Medina CB,Zhu Y,Zhao L,Serbulea V,Onengut-Gumuscu S,Leitinger N,Kucenas S,Rathmell JC,Makowski L,Ravichandran KS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Nov 01 00:00:00 EDT 2018

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Cell

Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Jun 28 00:00:00 EDT 2018

Chanzyme TRPM7 Mediates the Ca²⁺ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.

Immunity

Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jan 16 00:00:00 EST 2018

Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.

Immunity

Li X,Gadzinsky A,Gong L,Tong H,Calderon V,Li Y,Kitamura D,Klein U,Langdon WY,Hou F,Zou YR,Gu H

48-4801-82 was used in Flow Cytometry to show that deleting E3 ubiquitin ligases Cbl and Cbl-b (Cbls) in GC B cells results in the early exit of high-affinity antigen-specific B cells from the GC reaction and thus impaired clonal expansion.

Tue Mar 20 00:00:00 EDT 2018

The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis.

Cell host & microbe

Truax AD,Chen L,Tam JW,Cheng N,Guo H,Koblansky AA,Chou WC,Wilson JE,Brickey WJ,Petrucelli A,Liu R,Cooper DE,Koenigsknecht MJ,Young VB,Netea MG,Stienstra R,Sartor RB,Montgomery SA,Coleman RA,Ting JP

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Sep 12 00:00:00 EDT 2018

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain.

The Journal of clinical investigation

Bang S,Xie YK,Zhang ZJ,Wang Z,Xu ZZ,Ji RR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Aug 01 00:00:00 EDT 2018

PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy.

The Journal of clinical investigation

Zamarin D,Ricca JM,Sadekova S,Oseledchyk A,Yu Y,Blumenschein WM,Wong J,Gigoux M,Merghoub T,Wolchok JD

48-4801 was used in Flow cytometry/Cell sorting to use human tumour histocultures and syngeneic tumour models treated with Newcastle disease virus to identify immune targets upregulated by OV treatment.

Mon Apr 02 00:00:00 EDT 2018

Insulin resistance causes inflammation in adipose tissue.

The Journal of clinical investigation

Shimobayashi M,Albert V,Woelnerhanssen B,Frei IC,Weissenberger D,Meyer-Gerspach AC,Clement N,Moes S,Colombi M,Meier JA,Swierczynska MM,Jenö P,Beglinger C,Peterli R,Hall MN

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Apr 02 00:00:00 EDT 2018

Inhibition of neogenin fosters resolution of inflammation and tissue regeneration.

The Journal of clinical investigation

Schlegel M,Körner A,Kaussen T,Knausberg U,Gerber C,Hansmann G,Jónasdóttir HS,Giera M,Mirakaj V

48-4801 was used in Flow cytometry/Cell sorting to investigate whether the neuronal guidance protein, neogenin, modulates the mechanisms of inflammation resolution.

Mon Oct 01 00:00:00 EDT 2018

Myeloid p38α signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis.

EMBO molecular medicine

Youssif C,Cubillos-Rojas M,Comalada M,Llonch E,Perna C,Djouder N,Nebreda AR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Sun Jul 01 00:00:00 EDT 2018

Myeloid p38α signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis.

EMBO molecular medicine

Youssif C,Cubillos-Rojas M,Comalada M,Llonch E,Perna C,Djouder N,Nebreda AR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Sun Jul 01 00:00:00 EDT 2018

Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8⁺ T cell responses.

Journal of controlled release : official journal of the Controlled Release Society

Si Y,Wen Y,Kelly SH,Chong AS,Collier JH

48-4801 was used in Flow cytometry/Cell sorting to investigate the extent to which self-assembled peptide nanofibers bearing an influenza peptide epitope elicit antigen-specific CD8+ T cell responses when delivered intranasally, and compare these responses with those elicited by subcutaneous immunization.

Sat Jul 28 00:00:00 EDT 2018

De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.

Frontiers in immunology

Stüve P,Minarrieta L,Erdmann H,Arnold-Schrauf C,Swallow M,Guderian M,Krull F,Hölscher A,Ghorbani P,Behrends J,Abraham WR,Hölscher C,Sparwasser TD,Berod L

48-4801-82 was used in Flow Cytometry to reveal that acetyl-CoA carboxylase 1-dependent fatty acid synthesis is a crucial mechanism in T cells, but not dendritic cells or macrophages, to fight against mycobacterial infection.

Wed Apr 10 00:00:00 EDT 2019

Frontline Science: Macrophage-derived exosomes promote neutrophil necroptosis following hemorrhagic shock.

Journal of leukocyte biology

Jiao Y,Li Z,Loughran PA,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Shi X,Fan J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice.

International journal of obesity (2005)

Chang CJ,Lu CC,Lin CS,Martel J,Ko YF,Ojcius DM,Wu TR,Tsai YH,Yeh TS,Lu JJ,Lai HC,Young JD

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

Sustained Delivery of Doxorubicin via Acetalated Dextran Scaffold Prevents Glioblastoma Recurrence after Surgical Resection.

Molecular pharmaceutics

Graham-Gurysh E,Moore KM,Satterlee AB,Sheets KT,Lin FC,Bachelder EM,Miller CR,Hingtgen SD,Ainslie KM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Mar 05 00:00:00 EST 2018

Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice.

International journal of molecular medicine

Nguyễn-Thanh T,Kim D,Lee S,Kim W,Park SK,Kang KP

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Mon Jan 01 00:00:00 EST 2018

Endothelial dysfunction is a superinducer of syndecan-4: fibrogenic role of its ectodomain.

American journal of physiology. Heart and circulatory physiology

Lipphardt M,Song JW,Ratliff BB,Dihazi H,Müller GA,Goligorsky MS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Thu Mar 01 00:00:00 EST 2018

Endothelial dysfunction is a superinducer of syndecan-4: fibrogenic role of its ectodomain.

American journal of physiology. Heart and circulatory physiology

Lipphardt M,Song JW,Ratliff BB,Dihazi H,Müller GA,Goligorsky MS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Thu Mar 01 00:00:00 EST 2018

VEGF Receptor-2 Activation Mediated by VEGF-E Limits Scar Tissue Formation Following Cutaneous Injury.

Advances in wound care

Wise LM,Stuart GS,Real NC,Fleming SB,Mercer AA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Aug 01 00:00:00 EDT 2018

Deletion of endoplasmic reticulum stress-responsive co-chaperone p58^IPK protects mice from diet-induced steatohepatitis.

Hepatology research : the official journal of the Japan Society of Hepatology

Bandla H,Dasgupta D,Mauer AS,Nozickova B,Kumar S,Hirsova P,Graham RP,Malhi H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue May 01 00:00:00 EDT 2018

Primary cilia disruption differentially affects the infiltrating and resident macrophage compartment in the liver.

American journal of physiology. Gastrointestinal and liver physiology

Zimmerman KA,Song CJ,Gonzalez-Mize N,Li Z,Yoder BK

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

Evaluation of renal metabolic response to partial ureteral obstruction with hyperpolarized ¹³ C MRI.

NMR in biomedicine

Niles DJ,Gordon JW,Huang G,Reese S,Adamson EB,Djamali A,Fain SB

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (Paraffin)

Mon Jan 01 00:00:00 EST 2018

Characterization of Stress and Innate Immunity Resistance of Wild-Type and Δp66 Borrelia burgdorferi.

Infection and immunity

Curtis MW,Hahn BL,Zhang K,Li C,Robinson RT,Coburn J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis.

The Journal of biological chemistry

Gui Y,Li J,Lu Q,Feng Y,Wang M,He W,Yang J,Dai C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (Frozen)

Fri Oct 19 00:00:00 EDT 2018

The signaling protein Wnt5a promotes TGFβ1-mediated macrophage polarization and kidney fibrosis by inducing the transcriptional regulators Yap/Taz.

The Journal of biological chemistry

Feng Y,Liang Y,Zhu X,Wang M,Gui Y,Lu Q,Gu M,Xue X,Sun X,He W,Yang J,Johnson RL,Dai C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Fri Dec 14 00:00:00 EST 2018

The signaling protein Wnt5a promotes TGFβ1-mediated macrophage polarization and kidney fibrosis by inducing the transcriptional regulators Yap/Taz.

The Journal of biological chemistry

Feng Y,Liang Y,Zhu X,Wang M,Gui Y,Lu Q,Gu M,Xue X,Sun X,He W,Yang J,Johnson RL,Dai C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Fri Dec 14 00:00:00 EST 2018

Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression.

The Journal of biological chemistry

Hamlin AN,Chinnarasu S,Ding Y,Xian X,Herz J,Jaeschke A,Hui DY

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Jun 22 00:00:00 EDT 2018

Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression.

The Journal of biological chemistry

Hamlin AN,Chinnarasu S,Ding Y,Xian X,Herz J,Jaeschke A,Hui DY

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Jun 22 00:00:00 EDT 2018

Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis.

PloS one

Waterborg CEJ,Koenders MI,van Lent PLEM,van der Kraan PM,van de Loo FAJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Mar 27 00:00:00 EDT 2019

Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion.

Scientific reports

Mannaa M,Markó L,Balogh A,Vigolo E,N'diaye G,Kaßmann M,Michalick L,Weichelt U,Schmidt-Ott KM,Liedtke WB,Huang Y,Müller DN,Kuebler WM,Gollasch M

48-4801 was used in Flow cytometry/Cell sorting to investigate a putative organ protective role of transient receptor potential vanilloid 4 in acute renal ischaemia/reperfusion injury.

Tue Mar 20 00:00:00 EDT 2018

iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.

JCI insight

Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Feb 08 00:00:00 EST 2018

Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice.

The Journal of biological chemistry

Spurthi KM,Sarikhani M,Mishra S,Desingu PA,Yadav S,Rao S,Maity S,Tamta AK,Kumar S,Majumdar S,Jain A,Raghuraman A,Khan D,Singh I,Samuel RJ,Ramachandra SG,Nandi D,Sundaresan NR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Aug 24 00:00:00 EDT 2018

Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1.

The Journal of biological chemistry

Rijal D,Ariana A,Wight A,Kim K,Alturki NA,Aamir Z,Ametepe ES,Korneluk RG,Tiedje C,Menon MB,Gaestel M,McComb S,Sad S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Jul 27 00:00:00 EDT 2018

Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice.

Theranostics

Li X,Jia L,Chen X,Dong Y,Ren X,Dong Y,Chen Y,Xie L,Liu M,Shiota C,Gittes GK,Rui L,Chen Z

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Sep 05 00:00:00 EDT 2019

Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation.

Nature communications

Izumi T,Imai J,Yamamoto J,Kawana Y,Endo A,Sugawara H,Kohata M,Asai Y,Takahashi K,Kodama S,Kaneko K,Gao J,Uno K,Sawada S,Kalinichenko VV,Ishigaki Y,Yamada T,Katagiri H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Dec 13 00:00:00 EST 2018

BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells.

Oncotarget

Romano E,Rufo N,Korf H,Mathieu C,Garg AD,Agostinis P

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Apr 03 00:00:00 EDT 2018

MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity.

Frontiers in immunology

Knolle MD,Chin SB,Rana BMJ,Englezakis A,Nakagawa R,Fallon PG,Git A,McKenzie ANJ

48-4801 was used in Flow cytometry/Cell sorting to identify a subset of micro-RNAs that are regulated upon group-2 innate lymphoid cells (ILC2) activation, and establish a specific role for miR-155 in regulating ILC2 survival following activation.

Mon Sep 30 00:00:00 EDT 2019

An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages.

Scientific reports

Beneke V,Küster F,Neehus AL,Hesse C,Lopez-Rodriguez E,Haake K,Rafiei Hashtchin A,Schott JW,Walter D,Braun A,Wolkers WF,Ackermann M,Lachmann N

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Nov 02 00:00:00 EDT 2018

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

Immunity

Lim HY,Lim SY,Tan CK,Thiam CH,Goh CC,Carbajo D,Chew SHS,See P,Chakarov S,Wang XN,Lim LH,Johnson LA,Lum J,Fong CY,Bongso A,Biswas A,Goh C,Evrard M,Yeo KP,Basu R,Wang JK,Tan Y,Jain R,Tikoo S,Choong C,Weninger W,Poidinger M,Stanley RE,Collin M,Tan NS,Ng LG,Jackson DG,Ginhoux F,Angeli V

48-4801-82 was used in Flow cytometry/Cell sorting to unveil a hitherto unknown homeostatic contribution of arterial LYVE-1+ macrophages through the control of collagen production by SMCs and has identified a function of LYVE-1 in leukocytes.

Tue Aug 21 00:00:00 EDT 2018

Characterization of Multiple Cytokine Combinations and TGF-β on Differentiation and Functions of Myeloid-Derived Suppressor Cells.

International journal of molecular sciences

Lee CR,Lee W,Cho SK,Park SG

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Mar 15 00:00:00 EDT 2018

Collagen Type 1 Accelerates Healing of Ruptured Fetal Membranes.

Scientific reports

Mogami H,Kishore AH,Word RA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Jan 12 00:00:00 EST 2018

Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.

Nature

Camell CD,Sander J,Spadaro O,Lee A,Nguyen KY,Wing A,Goldberg EL,Youm YH,Brown CW,Elsworth J,Rodeheffer MS,Schultze JL,Dixit VD

48-4801 was used in Flow cytometry/Cell sorting to show that adipose tissue macrophages regulate the age-related reduction in adipocyte lipolysis in mice by lowering the bioavailability of noradrenaline.

Thu Oct 05 00:00:00 EDT 2017

T Cell Zone Resident Macrophages Silently Dispose of Apoptotic Cells in the Lymph Node.

Immunity

Baratin M,Simon L,Jorquera A,Ghigo C,Dembele D,Nowak J,Gentek R,Wienert S,Klauschen F,Malissen B,Dalod M,Bajénoff M

48-4801 was used in Flow cytometry/Cell sorting to characterise a population of CX3CR1+ MERTK+ cells located in the T cell zone of lymph nodes.

Tue Aug 15 00:00:00 EDT 2017

Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.

Cell host & microbe

Zhu F,Willette-Brown J,Song NY,Lomada D,Song Y,Xue L,Gray Z,Zhao Z,Davis SR,Sun Z,Zhang P,Wu X,Zhan Q,Richie ER,Hu Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Apr 12 00:00:00 EDT 2017

Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy.

Cell stem cell

Lechner AJ,Driver IH,Lee J,Conroy CM,Nagle A,Locksley RM,Rock JR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Jul 06 00:00:00 EDT 2017

T-Cell Mineralocorticoid Receptor Controls Blood Pressure by Regulating Interferon-Gamma.

Circulation research

Sun XN,Li C,Liu Y,Du LJ,Zeng MR,Zheng XJ,Zhang WC,Liu Y,Zhu M,Kong D,Zhou L,Lu L,Shen ZX,Yi Y,Du L,Qin M,Liu X,Hua Z,Sun S,Yin H,Zhou B,Yu Y,Zhang Z,Duan SZ

48-4801 was used in Flow cytometry/Cell sorting to determine the role of T-cell mineralocorticoid receptor in blood pressure regulation and explore the mechanism.

Fri May 12 00:00:00 EDT 2017

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.

The Journal of clinical investigation

Kim W,Khan SK,Gvozdenovic-Jeremic J,Kim Y,Dahlman J,Kim H,Park O,Ishitani T,Jho EH,Gao B,Yang Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jan 03 00:00:00 EST 2017

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.

The Journal of clinical investigation

Kim W,Khan SK,Gvozdenovic-Jeremic J,Kim Y,Dahlman J,Kim H,Park O,Ishitani T,Jho EH,Gao B,Yang Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jan 03 00:00:00 EST 2017

Intestinal fungi contribute to development of alcoholic liver disease.

The Journal of clinical investigation

Yang AM,Inamine T,Hochrath K,Chen P,Wang L,Llorente C,Bluemel S,Hartmann P,Xu J,Koyama Y,Kisseleva T,Torralba MG,Moncera K,Beeri K,Chen CS,Freese K,Hellerbrand C,Lee SM,Hoffman HM,Mehal WZ,Garcia-Tsao G,Mutlu EA,Keshavarzian A,Brown GD,Ho SB,Bataller R,Stärkel P,Fouts DE,Schnabl B

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Jun 30 00:00:00 EDT 2017

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.

The Journal of clinical investigation

Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.

The Journal of clinical investigation

Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity.

The Journal of experimental medicine

Thomas DC,Clare S,Sowerby JM,Pardo M,Juss JK,Goulding DA,van der Weyden L,Storisteanu D,Prakash A,Espéli M,Flint S,Lee JC,Hoenderdos K,Kane L,Harcourt K,Mukhopadhyay S,Umrania Y,Antrobus R,Nathan JA,Adams DJ,Bateman A,Choudhary JS,Lyons PA,Condliffe AM,Chilvers ER,Dougan G,Smith KG

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Apr 03 00:00:00 EDT 2017

ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.

The Journal of experimental medicine

Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG

48-4801 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.

Mon Sep 04 00:00:00 EDT 2017

(Pro)renin Receptor Is an Amplifier of Wnt/β-Catenin Signaling in Kidney Injury and Fibrosis.

Journal of the American Society of Nephrology : JASN

Li Z,Zhou L,Wang Y,Miao J,Hong X,Hou FF,Liu Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Tue Aug 01 00:00:00 EDT 2017

RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.

EMBO molecular medicine

Zhu H,Lou F,Yin Q,Gao Y,Sun Y,Bai J,Xu Z,Liu Z,Cai W,Ke F,Zhang L,Zhou H,Wang H,Wang G,Chen X,Zhang H,Wang Z,Ginhoux F,Lu C,Su B,Wang H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy.

Proceedings of the National Academy of Sciences of the United States of America

Nakanishi H,Kawashima Y,Kurima K,Chae JJ,Ross AM,Pinto-Patarroyo G,Patel SK,Muskett JA,Ratay JS,Chattaraj P,Park YH,Grevich S,Brewer CC,Hoa M,Kim HJ,Butman JA,Broderick L,Hoffman HM,Aksentijevich I,Kastner DL,Goldbach-Mansky R,Griffith AJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Sep 12 00:00:00 EDT 2017

Rictor/mammalian target of rapamycin complex 2 promotes macrophage activation and kidney fibrosis.

The Journal of pathology

Ren J,Li J,Feng Y,Shu B,Gui Y,Wei W,He W,Yang J,Dai C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Tue Aug 01 00:00:00 EDT 2017

p40 -Deficient Mice Exhibit Impaired Bacterial Clearance and Enhanced Pro-inflammatory Responses during Salmonella enterica serovar Typhimurium Infection.

Frontiers in immunology

Li Y,Lv M,Su C,Long S,Zhang W,Conway KL,Li W,Xavier RJ,Shi HN

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Nov 20 00:00:00 EST 2019

p40 -Deficient Mice Exhibit Impaired Bacterial Clearance and Enhanced Pro-inflammatory Responses during Salmonella enterica serovar Typhimurium Infection.

Frontiers in immunology

Li Y,Lv M,Su C,Long S,Zhang W,Conway KL,Li W,Xavier RJ,Shi HN

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Nov 20 00:00:00 EST 2019

p40 -Deficient Mice Exhibit Impaired Bacterial Clearance and Enhanced Pro-inflammatory Responses during Salmonella enterica serovar Typhimurium Infection.

Frontiers in immunology

Li Y,Lv M,Su C,Long S,Zhang W,Conway KL,Li W,Xavier RJ,Shi HN

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Nov 20 00:00:00 EST 2019

1,25-Dihydroxyvitamin D Inhibits LPS-Induced High-Mobility Group Box 1 (HMGB1) Secretion via Targeting the NF-E2-Related Factor 2-Hemeoxygenase-1-HMGB1 Pathway in Macrophages.

Frontiers in immunology

Rao Z,Zhang N,Xu N,Pan Y,Xiao M,Wu J,Zhou H,Yang S,Chen Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunocytochemistry

Wed Nov 20 00:00:00 EST 2019

Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.

Frontiers in immunology

Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Nov 20 00:00:00 EST 2019

Cigarette Smoke Increases CD8α⁺ Dendritic Cells in an Ovalbumin-Induced Airway Inflammation.

Frontiers in immunology

Brüggemann TR,Fernandes P,Oliveira LM,Sato MN,Martins MA,Arantes-Costa FM

48-4801 was used in Flow cytometry/Cell sorting to analyze how cigarette smoke affects pro-inflammatory and anti-inflammatory mediators in a murine model of allergic pulmonary inflammation.

Wed Nov 20 00:00:00 EST 2019

CCR2^- and CCR2⁺ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.

Mucosal immunology

Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Sep 01 00:00:00 EDT 2017

CCR2^- and CCR2⁺ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.

Mucosal immunology

Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Sep 01 00:00:00 EDT 2017

MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.

PLoS pathogens

Friedrich C,Mamareli P,Thiemann S,Kruse F,Wang Z,Holzmann B,Strowig T,Sparwasser T,Lochner M

48-4801 was used in Flow cytometry/Cell sorting to suggest that MyD88 signaling in DC and IEC is both essential and sufficient to induce a full spectrum of host responses upon intestinal infection with C. rodentium.

Mon May 01 00:00:00 EDT 2017

Macrophages are required to coordinate mouse digit tip regeneration.

Development (Cambridge, England)

Simkin J,Sammarco MC,Marrero L,Dawson LA,Yan M,Tucker C,Cammack A,Muneoka K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Nov 01 00:00:00 EDT 2017

Evaluation of trained immunity by β-1, 3 (d)-glucan on murine monocytes in vitro and duration of response in vivo.

Immunology and cell biology

Garcia-Valtanen P,Guzman-Genuino RM,Williams DL,Hayball JD,Diener KR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2017

Salmonella Meningitis Associated with Monocyte Infiltration in Mice.

The American journal of pathology

Bauler TJ,Starr T,Nagy TA,Sridhar S,Scott D,Winkler CW,Steele-Mortimer O,Detweiler CS,Peterson KE

48-4801 was used in Flow cytometry/Cell sorting to examine the ability of Salmonella enterica serovar Typhimurium to infect the central nervous system and cause meningitis following the natural route of infection in mice.

Sun Jan 01 00:00:00 EST 2017

Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria.

Journal of immunology (Baltimore, Md. : 1950)

Li Z,Jiao Y,Fan EK,Scott MJ,Li Y,Li S,Billiar TR,Wilson MA,Shi X,Fan J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Nov 01 00:00:00 EDT 2017

Amelioration of intestinal and systemic sequelae of murine Campylobacter jejuni infection by probiotic VSL#3 treatment.

Gut pathogens

Ekmekciu I,Fiebiger U,Stingl K,Bereswill S,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Sep 30 00:00:00 EDT 2020

Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy.

International journal of molecular medicine

Zhu Y,Zhang L,Lu Q,Gao Y,Cai Y,Sui A,Su T,Shen X,Xie B

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Aug 01 00:00:00 EDT 2017

Microarray analysis of circular RNA expression patterns in polarized macrophages.

International journal of molecular medicine

Zhang Y,Zhang Y,Li X,Zhang M,Lv K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2017

Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice.

Human molecular genetics

Deguise MO,De Repentigny Y,McFall E,Auclair N,Sad S,Kothary R

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Feb 15 00:00:00 EST 2017

ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.

RNA biology

Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu May 04 00:00:00 EDT 2017

The Second-Generation PGI2 Analogue Treprostinil Fails to Chemoprevent Tumors in a Murine Lung Adenocarcinoma Model.

Cancer prevention research (Philadelphia, Pa.)

Dwyer-Nield L,Hickey GA,Friedman M,Choo K,McArthur DG,Tennis MA,New ML,Geraci M,Keith RL

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Nov 01 00:00:00 EDT 2017

Zoledronic acid inhibits infiltration of tumor-associated macrophages and angiogenesis following transcatheter arterial chemoembolization in rat hepatocellular carcinoma models.

Oncology letters

Zhou DY,Qin J,Huang J,Wang F,Xu GP,Lv YT,Zhang JB,Shen LM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2017

High fat diet accelerates cartilage repair in DBA/1 mice.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Wei W,Bastiaansen-Jenniskens YM,Suijkerbuijk M,Kops N,Bos PK,Verhaar JAN,Zuurmond AM,Dell'Accio F,van Osch GJVM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Jun 01 00:00:00 EDT 2017

Anti-inflammatory effects of Fagopyrum cymosum administered as a potential drug for ulcerative colitis.

Experimental and therapeutic medicine

Ge F,Zhu S,Liu L,Yan J,Ji Y,Sun Z

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (Paraffin)

Wed Nov 01 00:00:00 EDT 2017

Phenotypic switch in lung interstitial macrophage polarization in an ovalbumin-induced mouse model of asthma.

Experimental and therapeutic medicine

Nie H,Wang A,He Q,Yang Q,Liu L,Zhang G,Huang Y,Ding X,Yu H,Hu S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2017

Macrophages are necessary for epimorphic regeneration in African spiny mice.

eLife

Simkin J,Gawriluk TR,Gensel JC,Seifert AW

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue May 16 00:00:00 EDT 2017

GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients.

JCI insight

Ban N,Siegfried CJ,Lin JB,Shui YB,Sein J,Pita-Thomas W,Sene A,Santeford A,Gordon M,Lamb R,Dong Z,Kelly SC,Cavalli V,Yoshino J,Apte RS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (Frozen)

Thu May 04 00:00:00 EDT 2017

GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients.

JCI insight

Ban N,Siegfried CJ,Lin JB,Shui YB,Sein J,Pita-Thomas W,Sene A,Santeford A,Gordon M,Lamb R,Dong Z,Kelly SC,Cavalli V,Yoshino J,Apte RS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry (Frozen)

Thu May 04 00:00:00 EDT 2017

Inhibitory effect of silymarin on CCl₄-induced liver fibrosis by reducing Ly6C^hi monocytes infiltration.

International journal of clinical and experimental pathology

Zhao XA,Chen GM,Liu Y,Chen YX,Wu HY,Chen J,Xiong YL,Tian C,Wang GY,Jia B,Xia J,Wang J,Yan XM,Zhang ZP,Huang R,Wu C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sun Jan 26 00:00:00 EST 2020

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

JCI insight

Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Sep 21 00:00:00 EDT 2017

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

JCI insight

Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Sep 21 00:00:00 EDT 2017

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

JCI insight

Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Sep 21 00:00:00 EDT 2017

PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy.

Scientific reports

Gao S,Li C,Zhu Y,Wang Y,Sui A,Zhong Y,Xie B,Shen X

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Feb 17 00:00:00 EST 2017

Intestinal and Systemic Immune Responses upon Multi-drug Resistant Pseudomonas aeruginosa Colonization of Mice Harboring a Human Gut Microbiota.

Frontiers in microbiology

von Klitzing E,Ekmekciu I,Bereswill S,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Sep 30 00:00:00 EDT 2020

Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis.

Nature communications

Reißig S,Tang Y,Nikolaev A,Gerlach K,Wolf C,Davari K,Gallus C,Masri J,Mufazalov IA,Neurath MF,Wunderlich FT,Schattenberg JM,Galle PR,Weigmann B,Waisman A,Glasmacher E,Hövelmeyer N

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Apr 28 00:00:00 EDT 2017

IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice.

Scientific reports

Shintani Y,Ito T,Fields L,Shiraishi M,Ichihara Y,Sato N,Podaru M,Kainuma S,Tanaka H,Suzuki K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Jul 31 00:00:00 EDT 2017

IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice.

Scientific reports

Shintani Y,Ito T,Fields L,Shiraishi M,Ichihara Y,Sato N,Podaru M,Kainuma S,Tanaka H,Suzuki K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Jul 31 00:00:00 EDT 2017

Gastric TFF1 Expression from Acute to Chronic Helicobacter Infection.

Frontiers in cellular and infection microbiology

Esposito R,Morello S,Vllahu M,Eletto D,Porta A,Tosco A

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Jul 09 00:00:00 EDT 2018

Omega-3 Polyunsaturated Fatty Acids Attenuate Fibroblast Activation and Kidney Fibrosis Involving MTORC2 Signaling Suppression.

Scientific reports

Zeng Z,Yang H,Wang Y,Ren J,Dai Y,Dai C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Apr 10 00:00:00 EDT 2017

Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.

Stem cell research & therapy

Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Nov 10 00:00:00 EST 2017

TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.

eLife

Ku AT,Shaver TM,Rao AS,Howard JM,Rodriguez CN,Miao Q,Garcia G,Le D,Yang D,Borowiak M,Cohen DN,Chitsazzadeh V,Diwan AH,Tsai KY,Nguyen H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed May 03 00:00:00 EDT 2017

Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival.

Nature communications

Buscher K,Ehinger E,Gupta P,Pramod AB,Wolf D,Tweet G,Pan C,Mills CD,Lusis AJ,Ley K

48-4801 was used in Flow cytometry/Cell sorting to highlight natural activation diversity as a disease relevant dimension in macrophage biology.

Mon Jul 24 00:00:00 EDT 2017

Alpha-lipoic acid ameliorates the epithelial mesenchymal transition induced by unilateral ureteral obstruction in mice.

Scientific reports

Cho HS,Kim JH,Jang HN,Lee TW,Jung MH,Kim TH,Chang SH,Park DJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Apr 05 00:00:00 EDT 2017

Plastic roles of pericytes in the blood-retinal barrier.

Nature communications

Park DY,Lee J,Kim J,Kim K,Hong S,Han S,Kubota Y,Augustin HG,Ding L,Kim JW,Kim H,He Y,Adams RH,Koh GY

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue May 16 00:00:00 EDT 2017

BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.

Scientific reports

Shim DW,Shin WY,Yu SH,Kim BH,Ye SK,Koppula S,Won HS,Kang TB,Lee KH

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Nov 08 00:00:00 EST 2017

Hyperhomocysteinemia Exacerbates Cisplatin-induced Acute Kidney Injury.

International journal of biological sciences

Long Y,Zhen X,Zhu F,Hu Z,Lei W,Li S,Zha Y,Nie J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Nov 07 00:00:00 EST 2017

Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus.

Nature communications

Llorente C,Jepsen P,Inamine T,Wang L,Bluemel S,Wang HJ,Loomba R,Bajaj JS,Schubert ML,Sikaroodi M,Gillevet PM,Xu J,Kisseleva T,Ho SB,DePew J,Du X,Sørensen HT,Vilstrup H,Nelson KE,Brenner DA,Fouts DE,Schnabl B

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Mon Oct 16 00:00:00 EDT 2017

Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.

Cell death & disease

Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease.

Stem cell reports

Friesen M,Camahort R,Lee YK,Xia F,Gerszten RE,Rhee EP,Deo RC,Cowan CA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue May 09 00:00:00 EDT 2017

Healing of Preterm Ruptured Fetal Membranes.

Scientific reports

Mogami H,Hari Kishore A,Akgul Y,Word RA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Oct 13 00:00:00 EDT 2017

IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge.

Cell reports

Spadaro O,Camell CD,Bosurgi L,Nguyen KY,Youm YH,Rothlin CV,Dixit VD

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Apr 11 00:00:00 EDT 2017

Mononuclear Phagocytes Are Dispensable for Cardiac Remodeling in Established Pressure-Overload Heart Failure.

PloS one

Patel B,Ismahil MA,Hamid T,Bansal SS,Prabhu SD

48-4801 was used in Flow cytometry/Cell sorting to assess for alterations in MPs.

Thu Aug 10 00:00:00 EDT 2017

Immunogenicity of Isogenic IgG in Aggregates and Immune Complexes.

PloS one

St Clair JB,Detanico T,Aviszus K,Kirchenbaum GA,Christie M,Carpenter JF,Wysocki LJ

48-4801 was used in Flow cytometry/Cell sorting to analyse CD4 T cell reactions against IgG in various physical states.

Fri Aug 11 00:00:00 EDT 2017

One Year Follow-Up Risk Assessment in SKH-1 Mice and Wounds Treated with an Argon Plasma Jet.

International journal of molecular sciences

Schmidt A,Woedtke TV,Stenzel J,Lindner T,Polei S,Vollmar B,Bekeschus S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Apr 19 00:00:00 EDT 2017

In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.

Particle and fibre toxicology

Jatana S,Palmer BC,Phelan SJ,Gelein R,DeLouise LA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Apr 14 00:00:00 EDT 2017

Dendritic cells, macrophages, NK and CD8⁺ T lymphocytes play pivotal roles in controlling HSV-1 in the trigeminal ganglia by producing IL1-beta, iNOS and granzyme B.

Virology journal

Lucinda N,Figueiredo MM,Pessoa NL,Santos BS,Lima GK,Freitas AM,Machado AM,Kroon EG,Antonelli LR,Campos MA

48-4801 was used in Flow cytometry/Cell sorting to provide strong evidence that the responses mediated by DCs, Mo/M?, NK and CD8+ T lymphocytes through IL-1β, iNOS and granzyme B production, respectively, together with the production of type I IFN early in the infection, are crucial to host defense against HSV-1.

Tue Feb 21 00:00:00 EST 2017

Macrophages unlock progression of breast cancer cells experiencing matrigel-segregation in transplantation models.

Scientific reports

Ogura M,Bridgeman VL,Malanchi I

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Sep 08 00:00:00 EDT 2017

The role of human cytochrome P450 2E1 in liver inflammation and fibrosis.

Hepatology communications

Xu J,Ma HY,Liang S,Sun M,Karin G,Koyama Y,Hu R,Quehenberger O,Davidson NO,Dennis EA,Kisseleva T,Brenner DA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Dec 01 00:00:00 EST 2017

Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.

PloS one

Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Sep 18 00:00:00 EDT 2017

Exercise training enhances in vivo clearance of endotoxin and attenuates inflammatory responses by potentiating Kupffer cell phagocytosis.

Scientific reports

Komine S,Akiyama K,Warabi E,Oh S,Kuga K,Ishige K,Togashi S,Yanagawa T,Shoda J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Sep 20 00:00:00 EDT 2017

Exercise training enhances in vivo clearance of endotoxin and attenuates inflammatory responses by potentiating Kupffer cell phagocytosis.

Scientific reports

Komine S,Akiyama K,Warabi E,Oh S,Kuga K,Ishige K,Togashi S,Yanagawa T,Shoda J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Sep 20 00:00:00 EDT 2017

EBI2 receptor regulates myelin development and inhibits LPC-induced demyelination.

Journal of neuroinflammation

Rutkowska A,Sailer AW,Dev KK

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Sat Dec 16 00:00:00 EST 2017

Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.

Immunity

Tian Y,Kuo CF,Akbari O,Ou JH

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue May 17 00:00:00 EDT 2016

Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.

Immunity

Tian Y,Kuo CF,Akbari O,Ou JH

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue May 17 00:00:00 EDT 2016

IFNγ and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic Carcinoma.

Cancer discovery

Long KB,Gladney WL,Tooker GM,Graham K,Fraietta JA,Beatty GL

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Apr 01 00:00:00 EDT 2016

IFNγ and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic Carcinoma.

Cancer discovery

Long KB,Gladney WL,Tooker GM,Graham K,Fraietta JA,Beatty GL

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Apr 01 00:00:00 EDT 2016

Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia.

Cancer discovery

Lee KE,Spata M,Bayne LJ,Buza EL,Durham AC,Allman D,Vonderheide RH,Simon MC

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Mar 01 00:00:00 EST 2016

Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury.

Proceedings of the National Academy of Sciences of the United States of America

Rantakari P,Patten DA,Valtonen J,Karikoski M,Gerke H,Dawes H,Laurila J,Ohlmeier S,Elima K,Hübscher SG,Weston CJ,Jalkanen S,Adams DH,Salmi M,Shetty S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Aug 16 00:00:00 EDT 2016

Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression.

Hypertension (Dallas, Tex. : 1979)

Wang H,Hou L,Kwak D,Fassett J,Xu X,Chen A,Chen W,Blazar BR,Xu Y,Hall JL,Ge JB,Bache RJ,Chen Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Jul 01 00:00:00 EDT 2016

Platelets Guide Leukocytes to Their Sites of Extravasation.

PLoS biology

Zuchtriegel G,Uhl B,Puhr-Westerheide D,Pörnbacher M,Lauber K,Krombach F,Reichel CA

48-4801 was used in Flow cytometry/Cell sorting to uncover a platelet-directed, spatiotemporally organised, multicellular crosstalk that is essential for effective trafficking of leukocytes to the site of inflammation.

Sun May 01 00:00:00 EDT 2016

Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer.

Oncogene

Das S,Rachagani S,Sheinin Y,Smith LM,Gurumurthy CB,Roy HK,Batra SK

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu May 19 00:00:00 EDT 2016

Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer.

Oncogene

Das S,Rachagani S,Sheinin Y,Smith LM,Gurumurthy CB,Roy HK,Batra SK

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu May 19 00:00:00 EDT 2016

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.

Immunology

Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sat Oct 01 00:00:00 EDT 2016

Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD.

Journal of lipid research

Chattopadhyay A,Navab M,Hough G,Grijalva V,Mukherjee P,Fogelman HR,Hwang LH,Faull KF,Lusis AJ,Reddy ST,Fogelman AM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD.

Journal of lipid research

Chattopadhyay A,Navab M,Hough G,Grijalva V,Mukherjee P,Fogelman HR,Hwang LH,Faull KF,Lusis AJ,Reddy ST,Fogelman AM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.

Journal of leukocyte biology

Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Periostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models.

Molecular cancer therapeutics

Park SY,Piao Y,Jeong KJ,Dong J,de Groot JF

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Sep 01 00:00:00 EDT 2016

Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes.

The American journal of pathology

Li C,Srivastava RK,Weng Z,Croutch CR,Agarwal A,Elmets CA,Afaq F,Athar M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Sat Oct 01 00:00:00 EDT 2016

Depletion of regulatory T cells leads to an exacerbation of delayed-type hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade.

Disease models & mechanisms

Atkinson SM,Hoffmann U,Hamann A,Bach E,Danneskiold-Samsøe NB,Kristiansen K,Serikawa K,Fox B,Kruse K,Haase C,Skov S,Nansen A

48-4801 was used in Flow cytometry/Cell sorting to investigate the role of regulatory T cells in delayed-type hypersensitivity arthritis through depletion, and the rescuing effect of IL-7 in connection to regulatory T cell depletion.

Fri Apr 01 00:00:00 EDT 2016

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.

Disease models & mechanisms

Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.

Disease models & mechanisms

Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines.

Journal of immunology (Baltimore, Md. : 1950)

Noges LE,White J,Cambier JC,Kappler JW,Marrack P

48-4801 was used in Flow cytometry/Cell sorting to investigate the contribution of host DNA released at the site of vaccine injection to the adjuvant activity of alum.

Mon Aug 15 00:00:00 EDT 2016

Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model.

Endocrinology

Gaide Chevronnay HP,Janssens V,Van Der Smissen P,Rocca CJ,Liao XH,Refetoff S,Pierreux CE,Cherqui S,Courtoy PJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Apr 01 00:00:00 EDT 2016

Low intensity vibration mitigates tumor progression and protects bone quantity and quality in a murine model of myeloma.

Bone

Pagnotti GM,Chan ME,Adler BJ,Shroyer KR,Rubin J,Bain SD,Rubin CT

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Temporal and spatial distribution of macrophage phenotype markers in the foreign body response to glutaraldehyde-crosslinked gelatin hydrogels.

Journal of biomaterials science. Polymer edition

Yu T,Wang W,Nassiri S,Kwan T,Dang C,Liu W,Spiller KL

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Dec 29 00:00:00 EST 2016

The natural behavior of mononuclear phagocytes in HTS formation.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Zhu Z,Ding J,Ma Z,Iwashina T,Tredget EE

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Jan 05 00:00:00 EST 2017

Endothelial sirtuin 1 inactivation enhances capillary rarefaction and fibrosis following kidney injury through Notch activation.

Biochemical and biophysical research communications

Kida Y,Zullo JA,Goligorsky MS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Sep 23 00:00:00 EDT 2016

Endothelial sirtuin 1 inactivation enhances capillary rarefaction and fibrosis following kidney injury through Notch activation.

Biochemical and biophysical research communications

Kida Y,Zullo JA,Goligorsky MS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Sep 23 00:00:00 EDT 2016

Pdgfrb-Cre targets lymphatic endothelial cells of both venous and non-venous origins.

Genesis (New York, N.Y. : 2000)

Ulvmar MH,Martinez-Corral I,Stanczuk L,Mäkinen T

48-4801 was used in Flow cytometry/Cell sorting to show that Pdgfrb-Cre does not target YS HemEC or YS-derived erythro-myeloid progenitors.

Wed Jun 01 00:00:00 EDT 2016

Macrophages form functional vascular mimicry channels in vivo.

Scientific reports

Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Nov 11 00:00:00 EST 2016

Macrophages form functional vascular mimicry channels in vivo.

Scientific reports

Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Nov 11 00:00:00 EST 2016

Macrophages form functional vascular mimicry channels in vivo.

Scientific reports

Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Nov 11 00:00:00 EST 2016

Enhancement of Anti-Hypoxic Activity and Differentiation of Cardiac Stem Cells by Supernatant Fluids from Cultured Macrophages that Phagocytized Dead Mesenchymal Stem Cells.

International journal of molecular sciences

Liu L,Jin X,Zhou Z,Shen C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Jul 20 00:00:00 EDT 2016

Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema.

JCI insight

Gardenier JC,Hespe GE,Kataru RP,Savetsky IL,Torrisi JS,Nores GDG,Dayan JJ,Chang D,Zampell J,Martínez-Corral I,Ortega S,Mehrara BJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Thu Sep 22 00:00:00 EDT 2016

Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.

Nature communications

Baptista MA,Keszei M,Oliveira M,Sunahara KK,Andersson J,Dahlberg CI,Worth AJ,Liedén A,Kuo IC,Wallin RP,Snapper SB,Eidsmo L,Scheynius A,Karlsson MC,Bouma G,Burns SO,Forsell MN,Thrasher AJ,Nylén S,Westerberg LS

48-4801 was used in Flow cytometry/Cell sorting to study the balance between activation of WASp and Rac2 signalling pathways in dendritic cells.

Mon Jul 18 00:00:00 EDT 2016

PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice.

Cell death & disease

Wang T,Wang Z,Yang P,Xia L,Zhou M,Wang S,Du J,Zhang J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Apr 07 00:00:00 EDT 2016

Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.

Stem cell reports

Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Aug 09 00:00:00 EDT 2016

Laminin regulates PDGFRβ(+) cell stemness and muscle development.

Nature communications

Yao Y,Norris EH,Mason CE,Strickland S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue May 03 00:00:00 EDT 2016

Cysteamine broadly improves the anti-plasmodial activity of artemisinins against murine blood stage and cerebral malaria.

Malaria journal

Moradin N,Torre S,Gauthier S,Tam M,Hawari J,Vandercruyssen K,De Spiegeleer B,Fortin A,Stevenson MM,Gros P

48-4801 was used in Flow cytometry/Cell sorting to evaluate the effect of artemisinins and cysteamine combination therapy on malarial phenotypes.

Fri May 06 00:00:00 EDT 2016

Evidence for a dynamic role for mononuclear phagocytes during endometrial repair and remodelling.

Scientific reports

Cousins FL,Kirkwood PM,Saunders PT,Gibson DA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Nov 09 00:00:00 EST 2016

Development of inCVAX, In situ Cancer Vaccine, and Its Immune Response in Mice with Hepatocellular Cancer.

Journal of clinical & cellular immunology

Qi X,Lam SS,Liu D,Kim DY,Ma L,Alleruzzo L,Chen W,Hode T,Henry CJ,Kaifi J,Kimchi ET,Li G,Staveley-O'Carroll KF

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Aug 01 00:00:00 EDT 2016

Role of Cystathionine Gamma-Lyase in Immediate Renal Impairment and Inflammatory Response in Acute Ischemic Kidney Injury.

Scientific reports

Markó L,Szijártó IA,Filipovic MR,Kaßmann M,Balogh A,Park JK,Przybyl L,N'diaye G,Krämer S,Anders J,Ishii I,Müller DN,Gollasch M

48-4801 was used in Flow cytometry/Cell sorting to suggest that the depletion of systemic cystathionine gamma-lyase enhances kidney ischemia/reperfusion injury outcome through reduced inflammatory responses.

Wed Jun 08 00:00:00 EDT 2016

Targeting STAT3 signaling reduces immunosuppressive myeloid cells in head and neck squamous cell carcinoma.

Oncoimmunology

Bu LL,Yu GT,Deng WW,Mao L,Liu JF,Ma SR,Fan TF,Hall B,Kulkarni AB,Zhang WF,Sun ZJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

NADPH Oxidases Are Essential for Macrophage Differentiation.

The Journal of biological chemistry

Xu Q,Choksi S,Qu J,Jang J,Choe M,Banfi B,Engelhardt JF,Liu ZG

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Sep 16 00:00:00 EDT 2016

Increased apoptosis and browning of TAK1-deficient adipocytes protects against obesity.

JCI insight

Sassmann-Schweda A,Singh P,Tang C,Wietelmann A,Wettschureck N,Offermanns S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu May 19 00:00:00 EDT 2016

EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta.

Scientific reports

Chen II,Caprioli A,Ohnuki H,Kwak H,Porcher C,Tosato G

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Jun 02 00:00:00 EDT 2016

Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome.

Scientific reports

Sakata K,Araki K,Nakano H,Nishina T,Komazawa-Sakon S,Murai S,Lee GE,Hashimoto D,Suzuki C,Uchiyama Y,Notohara K,Gukovskaya AS,Gukovsky I,Yamamura KI,Baba H,Ohmuraya M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Nov 15 00:00:00 EST 2016

C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease.

Oncotarget

Liu SH,Wu CT,Huang KH,Wang CC,Guan SS,Chen LP,Chiang CK

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Apr 19 00:00:00 EDT 2016

Perivascular Mast Cells Govern Shear Stress-Induced Arteriogenesis by Orchestrating Leukocyte Function.

Cell reports

Chillo O,Kleinert EC,Lautz T,Lasch M,Pagel JI,Heun Y,Troidl K,Fischer S,Caballero-Martinez A,Mauer A,Kurz ARM,Assmann G,Rehberg M,Kanse SM,Nieswandt B,Walzog B,Reichel CA,Mannell H,Preissner KT,Deindl E

48-4801 was used in Flow cytometry/Cell sorting to find that perivascular mast cells are central regulators of shear stress-induced arteriogenesis by orchestrating leukocyte function and growth factor/cytokine release.

Tue Aug 23 00:00:00 EDT 2016

Myeloid-Specific Blockade of Notch Signaling Attenuates Choroidal Neovascularization through Compromised Macrophage Infiltration and Polarization in Mice.

Scientific reports

Dou GR,Li N,Chang TF,Zhang P,Gao X,Yan XC,Liang L,Han H,Wang YS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Jun 24 00:00:00 EDT 2016

Myeloid-Specific Blockade of Notch Signaling Attenuates Choroidal Neovascularization through Compromised Macrophage Infiltration and Polarization in Mice.

Scientific reports

Dou GR,Li N,Chang TF,Zhang P,Gao X,Yan XC,Liang L,Han H,Wang YS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Jun 24 00:00:00 EDT 2016

Toll-like Receptor 4 on Macrophage Promotes the Development of Steatohepatitis-related Hepatocellular Carcinoma in Mice.

The Journal of biological chemistry

Miura K,Ishioka M,Minami S,Horie Y,Ohshima S,Goto T,Ohnishi H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri May 27 00:00:00 EDT 2016

Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner.

Immunity, inflammation and disease

Owusu-Boaitey N,Bauckman KA,Zhang T,Mysorekar IU

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2016

Identification of IFN-γ-producing T cells as the main mediators of the side effects associated to mouse interleukin-15 sustained exposure.

Oncotarget

Di Scala M,Gil-Fariña I,Olagüe C,Vales A,Sobrevals L,Fortes P,Corbacho D,González-Aseguinolaza G

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Aug 02 00:00:00 EDT 2016

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.

Scientific reports

Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Jun 15 00:00:00 EDT 2016

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.

Nature medicine

Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2015

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.

Nature

Brestoff JR,Kim BS,Saenz SA,Stine RR,Monticelli LA,Sonnenberg GF,Thome JJ,Farber DL,Lutfy K,Seale P,Artis D

48-4801 was used in Flow cytometry/Cell sorting to study how ILC2s can regulate adipose function and metabolic homeostasis.

Thu Mar 12 00:00:00 EDT 2015

Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice.

Cell metabolism

Kolodin D,van Panhuys N,Li C,Magnuson AM,Cipolletta D,Miller CM,Wagers A,Germain RN,Benoist C,Mathis D

48-4801 was used in Flow cytometry/Cell sorting to elucidate the means by which Treg cells accumulate in visceral adipose tissue as lean mice age.

Tue Apr 07 00:00:00 EDT 2015

Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses.

Nature immunology

Deng Z,Ma S,Zhou H,Zang A,Fang Y,Li T,Shi H,Liu M,Du M,Taylor PR,Zhu HH,Chen J,Meng G,Li F,Chen C,Zhang Y,Jia XM,Lin X,Zhang X,Pearlman E,Li X,Feng GS,Xiao H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Mon Jun 01 00:00:00 EDT 2015

Host microbiota constantly control maturation and function of microglia in the CNS.

Nature neuroscience

Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.

Nature cell biology

Costa-Silva B,Aiello NM,Ocean AJ,Singh S,Zhang H,Thakur BK,Becker A,Hoshino A,Mark MT,Molina H,Xiang J,Zhang T,Theilen TM,García-Santos G,Williams C,Ararso Y,Huang Y,Rodrigues G,Shen TL,Labori KJ,Lothe IM,Kure EH,Hernandez J,Doussot A,Ebbesen SH,Grandgenett PM,Hollingsworth MA,Jain M,Mallya K,Batra SK,Jarnagin WR,Schwartz RE,Matei I,Peinado H,Stanger BZ,Bromberg J,Lyden D

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Mon Jun 01 00:00:00 EDT 2015

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.

Nature cell biology

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Mon Jun 01 00:00:00 EDT 2015

Nonvenous origin of dermal lymphatic vasculature.

Circulation research

Martinez-Corral I,Ulvmar MH,Stanczuk L,Tatin F,Kizhatil K,John SW,Alitalo K,Ortega S,Makinen T

48-4801 was used in Flow cytometry/Cell sorting to investigate the origin of murine lymphatic vasculature, showing a significant contribution from nonvenous cells.

Fri May 08 00:00:00 EDT 2015

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.

The Journal of clinical investigation

Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.

The Journal of clinical investigation

Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.

The Journal of clinical investigation

Li W,Xiao J,Zhou X,Xu M,Hu C,Xu X,Lu Y,Liu C,Xue S,Nie L,Zhang H,Li Z,Zhang Y,Ji F,Hui L,Tao W,Wei B,Wang H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Nov 02 00:00:00 EST 2015

Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.

Science translational medicine

Hu-Lieskovan S,Mok S,Homet Moreno B,Tsoi J,Robert L,Goedert L,Pinheiro EM,Koya RC,Graeber TG,Comin-Anduix B,Ribas A

48-4801 was used in Flow cytometry/Cell sorting to investigate the use of BRAF and MEK inhibitors with immunotherapy in patients with BRAF(V600E) melanoma.

Wed Mar 18 00:00:00 EDT 2015

SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL.

Autophagy

Choi SH,Gonen A,Diehl CJ,Kim J,Almazan F,Witztum JL,Miller YI

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Feb 23 00:00:00 EST 2016

MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.

Proceedings of the National Academy of Sciences of the United States of America

Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Dec 29 00:00:00 EST 2015

Spatiotemporal expression dynamics of selectins govern the sequential extravasation of neutrophils and monocytes in the acute inflammatory response.

Arteriosclerosis, thrombosis, and vascular biology

Zuchtriegel G,Uhl B,Hessenauer ME,Kurz AR,Rehberg M,Lauber K,Krombach F,Reichel CA

48-4801 was used in Flow cytometry/Cell sorting to provide novel insights into the mechanisms initiating the sequential infiltration of the perivascular tissue by neutrophils and monocytes in the acute inflammatory response.

Wed Apr 01 00:00:00 EDT 2015

Dysregulated intrahepatic CD4⁺ T-cell activation drives liver inflammation in ileitis-prone SAMP1/YitFc mice.

Cellular and molecular gastroenterology and hepatology

Omenetti S,Brogi M,Goodman WA,Croniger CM,Eid S,Huang AY,Laffi G,Roskams T,Cominelli F,Pinzani M,Pizarro TT

48-4801 was used in Flow cytometry/Cell sorting to investigate how activated intrahepatic CD4(+) T-cells induce liver inflammation and contribute to experimental ileitis via locally-impaired hepatic immunosuppressive function.

Wed Jul 01 00:00:00 EDT 2015

Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.

Frontiers in immunology

Vogel AJ,Brown DM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Jul 10 00:00:00 EDT 2015

Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages.

Frontiers in immunology

Wex K,Schmid U,Just S,Wang X,Wurm R,Naumann M,Schlüter D,Nishanth G

48-4801 was used in Flow cytometry/Cell sorting to explore the role of CYLD on RIPK2-dependent antibacterial immune responses in macrophages.

Tue Feb 02 00:00:00 EST 2016

LynA regulates an inflammation-sensitive signaling checkpoint in macrophages.

eLife

Freedman TS,Tan YX,Skrzypczynska KM,Manz BN,Sjaastad FV,Goodridge HS,Lowell CA,Weiss A

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Oct 30 00:00:00 EDT 2015

Systemically delivered adipose stromal vascular fraction cells disseminate to peripheral artery walls and reduce vasomotor tone through a CD11b+ cell-dependent mechanism.

Stem cells translational medicine

Morris ME,Beare JE,Reed RM,Dale JR,LeBlanc AJ,Kaufman CL,Zheng H,Ng CK,Williams SK,Hoying JB

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Apr 01 00:00:00 EDT 2015

Systemically delivered adipose stromal vascular fraction cells disseminate to peripheral artery walls and reduce vasomotor tone through a CD11b+ cell-dependent mechanism.

Stem cells translational medicine

Morris ME,Beare JE,Reed RM,Dale JR,LeBlanc AJ,Kaufman CL,Zheng H,Ng CK,Williams SK,Hoying JB

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Apr 01 00:00:00 EDT 2015

IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function.

Inflammatory bowel diseases

Waddell A,Vallance JE,Moore PD,Hummel AT,Wu D,Shanmukhappa SK,Fei L,Washington MK,Minar P,Coburn LA,Nakae S,Wilson KT,Denson LA,Hogan SP,Rosen MJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Dec 01 00:00:00 EST 2015

Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease.

Disease models & mechanisms

Williams BB,Tebbutt NC,Buchert M,Putoczki TL,Doggett K,Bao S,Johnstone CN,Masson F,Hollande F,Burgess AW,Scott AM,Ernst M,Heath JK

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sat Aug 01 00:00:00 EDT 2015

Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance.

International journal of obesity (2005)

Khan IM,Perrard XY,Brunner G,Lui H,Sparks LM,Smith SR,Wang X,Shi ZZ,Lewis DE,Wu H,Ballantyne CM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun Nov 01 00:00:00 EDT 2015

The Tec Kinase-Regulated Phosphoproteome Reveals a Mechanism for the Regulation of Inhibitory Signals in Murine Macrophages.

Journal of immunology (Baltimore, Md. : 1950)

Tampella G,Kerns HM,Niu D,Singh S,Khim S,Bosch KA,Garrett ME,Moguche A,Evans E,Browning B,Jahan TA,Nacht M,Wolf-Yadlin A,Plebani A,Hamerman JA,Rawlings DJ,James RG

48-4801 was used in Flow cytometry/Cell sorting to suggest that Tec kinases (Btk, Tec, Bmx) are required for TLR-dependent signaling in many types of myeloid cells.

Wed Jul 01 00:00:00 EDT 2015

Ten Weeks of Infection with a Tissue-Invasive Helminth Protects against Local Immune Complex-Mediated Inflammation, but Not Cutaneous Type I Hypersensitivity, in Previously Sensitized Mice.

Journal of immunology (Baltimore, Md. : 1950)

Evans H,Killoran KE,Mitre BK,Morris CP,Kim SY,Mitre E

48-4801 was used in Flow cytometry/Cell sorting to demonstrate that chronic filarial infection suppresses eosinophilic responses to antibody-mediated activation.

Thu Oct 01 00:00:00 EDT 2015

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice.

Endocrinology

Schoiswohl G,Stefanovic-Racic M,Menke MN,Wills RC,Surlow BA,Basantani MK,Sitnick MT,Cai L,Yazbeck CF,Stolz DB,Pulinilkunnil T,O'Doherty RM,Kershaw EE

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2015

Treatment of Inherited Eye Defects by Systemic Hematopoietic Stem Cell Transplantation.

Investigative ophthalmology & visual science

Rocca CJ,Kreymerman A,Ur SN,Frizzi KE,Naphade S,Lau A,Tran T,Calcutt NA,Goldberg JL,Cherqui S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Sun Nov 01 00:00:00 EDT 2015

Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.

Carcinogenesis

Dabydeen SA,Kang K,Díaz-Cruz ES,Alamri A,Axelrod ML,Bouker KB,Al-Kharboosh R,Clarke R,Hennighausen L,Furth PA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Jan 01 00:00:00 EST 2015

A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages.

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Keswani RK,Yoon GS,Sud S,Stringer KA,Rosania GR

Tue Sep 01 00:00:00 EDT 2015

Hedgehog signaling indirectly affects tubular cell survival after obstructive kidney injury.

American journal of physiology. Renal physiology

Rauhauser AA,Ren C,Lu D,Li B,Zhu J,McEnery K,Vadnagara K,Zepeda-Orozco D,Zhou XJ,Lin F,Jetten AM,Attanasio M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sun Nov 01 00:00:00 EDT 2015

Chemokine receptor Cxcr4 contributes to kidney fibrosis via multiple effectors.

American journal of physiology. Renal physiology

Yuan A,Lee Y,Choi U,Moeckel G,Karihaloo A

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2015

Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.

Tissue engineering. Part A

Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Apr 01 00:00:00 EDT 2015

Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway.

BioMed research international

Jin X,Yao T,Zhou Z,Zhu J,Zhang S,Hu W,Shen C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Mar 18 00:00:00 EDT 2016

CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer.

PloS one

Mazumdar S,Arendt LM,Phillips S,Sedic M,Kuperwasser C,Gill G

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Feb 09 00:00:00 EST 2016

Alveolar macrophage phenotype expression in airway-instilled bone marrow cells in mice.

SpringerPlus

Okui M,Goto T,Asakura K,Kamiyama I,Ohtsuka T

48-4801 was used in Flow cytometry/Cell sorting to study how intratracheally instilled bone marrow cells adapt to the surrounding microenvironment, directly differentiating into alveolar macrophages, and remain in the alveolar space for at least 3 months.

Mon Dec 21 00:00:00 EST 2015

Numb is required to prevent p53-dependent senescence following skeletal muscle injury.

Nature communications

Le Roux I,Konge J,Le Cam L,Flamant P,Tajbakhsh S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Oct 27 00:00:00 EDT 2015

Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug.

Nature communications

Miller MA,Zheng YR,Gadde S,Pfirschke C,Zope H,Engblom C,Kohler RH,Iwamoto Y,Yang KS,Askevold B,Kolishetti N,Pittet M,Lippard SJ,Farokhzad OC,Weissleder R

48-4801 was used in Flow cytometry/Cell sorting to reveal that TAMs serve as a slow release reservoir, accumulating significant vehicle from which DNA-damaging payload targets neighbouring tumour cells.

Tue Oct 27 00:00:00 EDT 2015

Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

PloS one

Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Apr 28 00:00:00 EDT 2016

Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality.

PloS one

Kraut B,Maier HJ,Kókai E,Fiedler K,Boettger T,Illing A,Kostin S,Walther P,Braun T,Wirth T

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Mon Jun 13 00:00:00 EDT 2016

Therapeutic manipulation of angiogenesis with miR-27b.

Vascular cell

Veliceasa D,Biyashev D,Qin G,Misener S,Mackie AR,Kishore R,Volpert OV

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Jul 10 00:00:00 EDT 2015

Vascular Notch proteins and Notch signaling in the peri-implantation mouse uterus.

Vascular cell

Shawber CJ,Lin L,Gnarra M,Sauer MV,Papaioannou VE,Kitajewski JK,Douglas NC

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Dec 02 00:00:00 EST 2015

Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.

Nature communications

Singh NK,Kotla S,Dyukova E,Traylor JG,Orr AW,Chernoff J,Marion TN,Rao GN

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Jun 24 00:00:00 EDT 2015

Structure-based programming of lymph-node targeting in molecular vaccines.

Nature

Liu H,Moynihan KD,Zheng Y,Szeto GL,Li AV,Huang B,Van Egeren DS,Park C,Irvine DJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Mar 27 00:00:00 EDT 2014

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.

Nature

Colegio OR,Chu NQ,Szabo AL,Chu T,Rhebergen AM,Jairam V,Cyrus N,Brokowski CE,Eisenbarth SC,Phillips GM,Cline GW,Phillips AJ,Medzhitov R

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Sep 25 00:00:00 EDT 2014

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.

Cancer cell

Xu C,Fillmore CM,Koyama S,Wu H,Zhao Y,Chen Z,Herter-Sprie GS,Akbay EA,Tchaicha JH,Altabef A,Reibel JB,Walton Z,Ji H,Watanabe H,Jänne PA,Castrillon DH,Rustgi AK,Bass AJ,Freeman GJ,Padera RF,Dranoff G,Hammerman PS,Kim CF,Wong KK

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon May 12 00:00:00 EDT 2014

A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity.

Cell metabolism

Hernandez ED,Lee SJ,Kim JY,Duran A,Linares JF,Yajima T,Müller TD,Tschöp MH,Smith SR,Diaz-Meco MT,Moscat J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Sep 02 00:00:00 EDT 2014

A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity.

Cell metabolism

Hernandez ED,Lee SJ,Kim JY,Duran A,Linares JF,Yajima T,Müller TD,Tschöp MH,Smith SR,Diaz-Meco MT,Moscat J

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Sep 02 00:00:00 EDT 2014

A role for the ITAM signaling module in specifying cytokine-receptor functions.

Nature immunology

Bezbradica JS,Rosenstein RK,DeMarco RA,Brodsky I,Medzhitov R

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Apr 01 00:00:00 EDT 2014

EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation.

Nature cell biology

Lanaya H,Natarajan A,Komposch K,Li L,Amberg N,Chen L,Wculek SK,Hammer M,Zenz R,Peck-Radosavljevic M,Sieghart W,Trauner M,Wang H,Sibilia M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Oct 01 00:00:00 EDT 2014

Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis.

The Journal of clinical investigation

Zhou HF,Yan H,Pan H,Hou KK,Akk A,Springer LE,Hu Y,Allen JS,Wickline SA,Pham CT

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed Oct 01 00:00:00 EDT 2014

Cell-specific translational profiling in acute kidney injury.

The Journal of clinical investigation

Liu J,Krautzberger AM,Sui SH,Hofmann OM,Chen Y,Baetscher M,Grgic I,Kumar S,Humphreys BD,Hide WA,McMahon AP

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sat Mar 01 00:00:00 EST 2014

Mouse hepatocyte overexpression of NF-κB-inducing kinase (NIK) triggers fatal macrophage-dependent liver injury and fibrosis.

Hepatology (Baltimore, Md.)

Shen H,Sheng L,Chen Z,Jiang L,Su H,Yin L,Omary MB,Rui L

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Dec 01 00:00:00 EST 2014

Mouse hepatocyte overexpression of NF-κB-inducing kinase (NIK) triggers fatal macrophage-dependent liver injury and fibrosis.

Hepatology (Baltimore, Md.)

Shen H,Sheng L,Chen Z,Jiang L,Su H,Yin L,Omary MB,Rui L

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Dec 01 00:00:00 EST 2014

Macrophages contribute to the cyclic activation of adult hair follicle stem cells.

PLoS biology

Castellana D,Paus R,Perez-Moreno M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Dec 01 00:00:00 EST 2014

Macrophages contribute to the cyclic activation of adult hair follicle stem cells.

PLoS biology

Castellana D,Paus R,Perez-Moreno M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Dec 01 00:00:00 EST 2014

T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.

Mucosal immunology

Chu DK,Mohammed-Ali Z,Jiménez-Saiz R,Walker TD,Goncharova S,Llop-Guevara A,Kong J,Gordon ME,Barra NG,Gillgrass AE,Van Seggelen H,Khan WI,Ashkar AA,Bramson JL,Humbles AA,Kolbeck R,Waserman S,Jordana M

48-4801 was used in Flow cytometry/Cell sorting to reveal intestinal Th2 priming is initiated by an autocrine/paracrine acting CD4(+) Th cell-intrinsic IL-4 program that is controlled by DC OX40L.

Sat Nov 01 00:00:00 EDT 2014

Pharmacological mobilization of endogenous stem cells significantly promotes skin regeneration after full-thickness excision: the synergistic activity of AMD3100 and tacrolimus.

The Journal of investigative dermatology

Lin Q,Wesson RN,Maeda H,Wang Y,Cui Z,Liu JO,Cameron AM,Gao B,Montgomery RA,Williams GM,Sun Z

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Mon Sep 01 00:00:00 EDT 2014

Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier.

PLoS pathogens

Nacer A,Movila A,Sohet F,Girgis NM,Gundra UM,Loke P,Daneman R,Frevert U

48-4801 was used in Flow cytometry/Cell sorting to show that significantly more CD8(+) T cells, neutrophils, and macrophages are recruited to postcapillary venules during ECM compared to hyperparasitemia.

Mon Dec 01 00:00:00 EST 2014

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.

Development (Cambridge, England)

Gilmour J,Assi SA,Jaegle U,Kulu D,van de Werken H,Clarke D,Westhead DR,Philipsen S,Bonifer C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Sun Jun 01 00:00:00 EDT 2014

The plexin C1 receptor promotes acute inflammation.

European journal of immunology

König K,Marth L,Roissant J,Granja T,Jennewein C,Devanathan V,Schneider M,Köhler D,Zarbock A,Rosenberger P

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Sep 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

48-4801 was used in Immunohistochemistry to identify cells of haematopoietic origin recruited to the wound site to deposit collagen, confirming the existence of fibrocytes in cutaneous healing.

Thu May 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

48-4801 was used in Immunohistochemistry to identify cells of haematopoietic origin recruited to the wound site to deposit collagen, confirming the existence of fibrocytes in cutaneous healing.

Thu May 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

48-4801 was used in Immunohistochemistry to identify cells of haematopoietic origin recruited to the wound site to deposit collagen, confirming the existence of fibrocytes in cutaneous healing.

Thu May 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

48-4801 was used in Immunohistochemistry to identify cells of haematopoietic origin recruited to the wound site to deposit collagen, confirming the existence of fibrocytes in cutaneous healing.

Thu May 01 00:00:00 EDT 2014

Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells.

Disease models & mechanisms

Kong XY,Nesset CK,Damme M,Løberg EM,Lübke T,Mæhlen J,Andersson KB,Lorenzo PI,Roos N,Thoresen GH,Rustan AC,Kase ET,Eskild W

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Sat Mar 01 00:00:00 EST 2014

The impact of Toll-like-receptor-9 on intestinal microbiota composition and extra-intestinal sequelae in experimental Toxoplasma gondii induced ileitis.

Gut pathogens

Bereswill S,Kühl AA,Alutis M,Fischer A,Möhle L,Struck D,Liesenfeld O,Göbel UB,Dunay IR,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Jun 16 00:00:00 EDT 2014

VEGFR-1 blockade disrupts peri-implantation decidual angiogenesis and macrophage recruitment.

Vascular cell

Douglas NC,Zimmermann RC,Tan QK,Sullivan-Pyke CS,Sauer MV,Kitajewski JK,Shawber CJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Aug 07 00:00:00 EDT 2014

VEGFR-1 blockade disrupts peri-implantation decidual angiogenesis and macrophage recruitment.

Vascular cell

Douglas NC,Zimmermann RC,Tan QK,Sullivan-Pyke CS,Sauer MV,Kitajewski JK,Shawber CJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Aug 07 00:00:00 EDT 2014

The role of serine protease HtrA in acute ulcerative enterocolitis and extra-intestinal immune responses during Campylobacter jejuni infection of gnotobiotic IL-10 deficient mice.

Frontiers in cellular and infection microbiology

Heimesaat MM,Alutis M,Grundmann U,Fischer A,Tegtmeyer N,Böhm M,Kühl AA,Göbel UB,Backert S,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Sep 19 00:00:00 EDT 2014

Nucleotide-oligomerization-domain-2 affects commensal gut microbiota composition and intracerebral immunopathology in acute Toxoplasma gondii induced murine ileitis.

PloS one

Heimesaat MM,Dunay IR,Alutis M,Fischer A,Möhle L,Göbel UB,Kühl AA,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Dec 18 00:00:00 EST 2015

Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.

PloS one

Karpurapu M,Ranjan R,Deng J,Chung S,Lee YG,Xiao L,Nirujogi TS,Jacobson JR,Park GY,Christman JW

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jan 20 00:00:00 EST 2015

Niacin reverses migratory macrophage foam cell arrest mediated by oxLDL in vitro.

PloS one

Huang H,Koelle P,Fendler M,Schroettle A,Czihal M,Hoffmann U,Kuhlencordt PJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Dec 17 00:00:00 EST 2015

The macrophage A2B adenosine receptor regulates tissue insulin sensitivity.

PloS one

Johnston-Cox H,Eisenstein AS,Koupenova M,Carroll S,Ravid K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Jan 12 00:00:00 EST 2015

Influenza virus-induced lung inflammation was modulated by cigarette smoke exposure in mice.

PloS one

Han Y,Ling MT,Mao H,Zheng J,Liu M,Lam KT,Liu Y,Tu W,Lau YL

48-4801 was used in Flow cytometry/Cell sorting to investigate the effect of cigarette smoke on pandemic H1N1 or H9N2 virus infection, showing that virus-induced lung inflammation was modulated by cigarette smoke exposure.

Wed Oct 29 00:00:00 EDT 2014

Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.

PloS one

Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Jun 10 00:00:00 EDT 2015

The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.

Cancer cell

Xiao Z,Jiang Q,Willette-Brown J,Xi S,Zhu F,Burkett S,Back T,Song NY,Datla M,Sun Z,Goldszmid R,Lin F,Cohoon T,Pike K,Wu X,Schrump DS,Wong KK,Young HA,Trinchieri G,Wiltrout RH,Hu Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Apr 15 00:00:00 EDT 2013

Modular 'click-in-emulsion' bone-targeted nanogels.

Advanced materials (Deerfield Beach, Fla.)

Heller DA,Levi Y,Pelet JM,Doloff JC,Wallas J,Pratt GW,Jiang S,Sahay G,Schroeder A,Schroeder JE,Chyan Y,Zurenko C,Querbes W,Manzano M,Kohane DS,Langer R,Anderson DG

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Wed Mar 13 00:00:00 EDT 2013

Genetic ablation of epidermal EGFR reveals the dynamic origin of adverse effects of anti-EGFR therapy.

Science translational medicine

Mascia F,Lam G,Keith C,Garber C,Steinberg SM,Kohn E,Yuspa SH

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Aug 21 00:00:00 EDT 2013

Dose-dense chemotherapy improves mechanisms of antitumor immune response.

Cancer research

Chang CL,Hsu YT,Wu CC,Lai YZ,Wang C,Yang YC,Wu TC,Hung CF

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2013

Imaging primary mouse sarcomas after radiation therapy using cathepsin-activatable fluorescent imaging agents.

International journal of radiation oncology, biology, physics

Cuneo KC,Mito JK,Javid MP,Ferrer JM,Kim Y,Lee WD,Bawendi MG,Brigman BE,Kirsch DG

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Wed May 01 00:00:00 EDT 2013

Thrombospondin-1 Silencing Down-Regulates Integrin Expression Levels in Human Anaplastic Thyroid Cancer Cells with BRAF(V600E): New Insights in the Host Tissue Adaptation and Homeostasis of Tumor Microenvironment.

Frontiers in endocrinology

Duquette M,Sadow PM,Lawler J,Nucera C

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Dec 18 00:00:00 EST 2013

Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing Cre recombinase exclusively in eosinophils.

Journal of leukocyte biology

Doyle AD,Jacobsen EA,Ochkur SI,Willetts L,Shim K,Neely J,Kloeber J,Lesuer WE,Pero RS,Lacy P,Moqbel R,Lee NA,Lee JJ

48-4801 was used in Flow cytometry/Cell sorting to develop a novel murine strain to allow a better definition of the role of eosinophils in health and disease.

Mon Jul 01 00:00:00 EDT 2013

Recipient myeloid-derived immunomodulatory cells induce PD-1 ligand-dependent donor CD4+Foxp3+ regulatory T cell proliferation and donor-recipient immune tolerance after murine nonmyeloablative bone marrow transplantation.

Journal of immunology (Baltimore, Md. : 1950)

van der Merwe M,Abdelsamed HA,Seth A,Ong T,Vogel P,Pillai AB

48-4801 was used in Flow cytometry/Cell sorting to investigate the specific mechanisms of immune tolerance following TLI/ATS conditioning, showing the induction of PD-1 ligand-dependent donor Treg proliferation and donor-recipient immune tolerance.

Sun Dec 01 00:00:00 EST 2013

CD11b+GR1+ myeloid cells secrete NGF and promote trigeminal ganglion neurite growth: implications for corneal nerve regeneration.

Investigative ophthalmology & visual science

Sarkar J,Chaudhary S,Jassim SH,Ozturk O,Chamon W,Ganesh B,Tibrewal S,Gandhi S,Byun YS,Hallak J,Mahmud DL,Mahmud N,Rondelli D,Jain S

48-4801 was used in Flow cytometry/Cell sorting to study trigeminal ganglion neurites using mice with fluorescent bone marrow cells to show increased growth when CD11b+GR1+ myeloid cells secrete NGF.

Tue Sep 03 00:00:00 EDT 2013

Dietary oleic acid increases m2 macrophages in the mesenteric adipose tissue.

PloS one

Camell C,Smith CW

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon May 12 00:00:00 EDT 2014

VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineered mouse model of lung adenocarcinoma.

BMC cancer

Majeti BK,Lee JH,Simmons BH,Shojaei F

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Apr 29 00:00:00 EDT 2013

Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis.

PloS one

Harmel-Laws E,Mann EA,Cohen MB,Steinbrecher KA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Aug 18 00:00:00 EDT 2014

The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.

The Journal of biological chemistry

Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Fri Jul 19 00:00:00 EDT 2013

Survey of extra-intestinal immune responses in asymptomatic long-term Campylobacter jejuni-infected mice.

European journal of microbiology & immunology

Heimesaat MM,Haag LM,Fischer A,Otto B,Kühl AA,Göbel UB,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sun Sep 01 00:00:00 EDT 2013

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.

Blood

He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Oct 11 00:00:00 EDT 2012

Induction of autophagy is essential for monocyte-macrophage differentiation.

Blood

Zhang Y,Morgan MJ,Chen K,Choksi S,Liu ZG

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Mar 22 00:00:00 EDT 2012

Tubular cell dedifferentiation and peritubular inflammation are coupled by the transcription regulator Id1 in renal fibrogenesis.

Kidney international

Li Y,Wen X,Liu Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue May 01 00:00:00 EDT 2012

Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice.

Hepatology (Baltimore, Md.)

Ishikawa T,Factor VM,Marquardt JU,Raggi C,Seo D,Kitade M,Conner EA,Thorgeirsson SS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sun Apr 01 00:00:00 EDT 2012

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages.

Proceedings of the National Academy of Sciences of the United States of America

Chen X,Barozzi I,Termanini A,Prosperini E,Recchiuti A,Dalli J,Mietton F,Matteoli G,Hiebert S,Natoli G

48-4801 was used in Flow cytometry/Cell sorting to elucidate the importance of histone deacetylase 3 for the inflammatory gene expression programme in macrophages.

Tue Oct 16 00:00:00 EDT 2012

Improvement of CXCR4 tracer specificity for PET imaging.

Journal of controlled release : official journal of the Controlled Release Society

Jacobson O,Weiss ID,Szajek LP,Niu G,Ma Y,Kiesewetter DO,Peled A,Eden HS,Farber JM,Chen X

48-4801 was used in in vitro experiments to report two new tracers based on the CXCR4 peptide antagonist that bind to CXCR4, but not to undesired targets, increasing specificity for PET imaging.

Mon Jan 30 00:00:00 EST 2012

Eosinophil contamination of thioglycollate-elicited peritoneal macrophage cultures skews the functional readouts of in vitro assays.

Journal of leukocyte biology

Misharin AV,Saber R,Perlman H

48-4801 was used in Flow cytometry/Cell sorting to examine the presence of other cell types in freshly isolated and cultured thioglycollate-elicited peritoneal cells.

Wed Aug 01 00:00:00 EDT 2012

Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms.

The American journal of pathology

Ninković J,Roy S

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Mar 01 00:00:00 EST 2012

Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages.

Journal of immunology (Baltimore, Md. : 1950)

Bosmann M,Haggadone MD,Hemmila MR,Zetoune FS,Sarma JV,Ward PA

48-4801 was used in Flow cytometry/Cell sorting to provide evidence of complement activation selectively interfering with production of T cell regulatory cytokines by APCs.

Tue May 15 00:00:00 EDT 2012

Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen.

Journal of immunology (Baltimore, Md. : 1950)

Hayashi C,Papadopoulos G,Gudino CV,Weinberg EO,Barth KR,Madrigal AG,Chen Y,Ning H,LaValley M,Gibson FC,Hamilton JA,Genco CA

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Oct 01 00:00:00 EDT 2012

The uncoordinated-5 homolog B receptor affects hepatic ischemia reperfusion injury.

PloS one

König K,Köhler D,Granja T,Jennewein C,Tran N,Mirakaj V,Kröhnert F,Rosenberger P

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Apr 02 00:00:00 EDT 2013

Saposin C coupled lipid nanovesicles specifically target arthritic mouse joints for optical imaging of disease severity.

PloS one

Qi X,Flick MJ,Frederick M,Chu Z,Mason R,DeLay M,Thornton S

48-4801 was used in Flow cytometry/Cell sorting to test a novel agent, SapC-DOPS-CVM, for assessing rheumatoid arthritis disease severity.

Fri Aug 03 00:00:00 EDT 2012

Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain.

Journal of neuroinflammation

Howe CL,Lafrance-Corey RG,Sundsbak RS,Lafrance SJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Mar 09 00:00:00 EST 2012

PI3Kγ drives priming and survival of autoreactive CD4(+) T cells during experimental autoimmune encephalomyelitis.

PloS one

Comerford I,Litchfield W,Kara E,McColl SR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Feb 26 00:00:00 EST 2013

p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.

Blood

Cudejko C,Wouters K,Fuentes L,Hannou SA,Paquet C,Bantubungi K,Bouchaert E,Vanhoutte J,Fleury S,Remy P,Tailleux A,Chinetti-Gbaguidi G,Dombrowicz D,Staels B,Paumelle R

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2011

Blockade of Wnt/β-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury.

Journal of the American Society of Nephrology : JASN

He W,Kang YS,Dai C,Liu Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sat Jan 01 00:00:00 EST 2011

MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Bosmann M,Patel VR,Russkamp NF,Pache F,Zetoune FS,Sarma JV,Ward PA

48-4801 was used in Flow cytometry/Cell sorting to study the expression and release of IL-17F and its regulation by the complement system.

Thu Dec 01 00:00:00 EST 2011

MMP9 is protective against lethal inflammatory mass lesions in the mouse colon.

Disease models & mechanisms

Hald A,Rønø B,Melander MC,Ding M,Holck S,Lund LR

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Mar 01 00:00:00 EST 2011

DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity.

Journal of immunology (Baltimore, Md. : 1950)

Guerriero JL,Ditsworth D,Catanzaro JM,Sabino G,Furie MB,Kew RR,Crawford HC,Zong WX

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Mar 15 00:00:00 EDT 2011

Myeloid cells migrate in response to IL-24.

Cytokine

Buzas K,Oppenheim JJ,Zack Howard OM

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2011

High phosphate diet reduces atherosclerosis formation in apolipoprotein E-deficient mice.

Journal of clinical biochemistry and nutrition

Shiota A,Taketani Y,Maekawa Y,Yasutomo K,Sata M,Sakai T,Mizuno R,Isshiki M,Yamamoto H,Takeda E

48-4801 was used in Flow cytometry/Cell sorting to investigate how excess phosphate intake decreases atherosclerosis formation by changing the profile of peripheral monocytes or inducing apoptosis of macrophages in apolipoprotein E-deficient mice.

Thu Sep 01 00:00:00 EDT 2011

Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery.

Frontiers in immunology

Bouvier I,Jusforgues-Saklani H,Lim A,Lemaître F,Lemercier B,Auriau C,Nicola MA,Leroy S,Law HK,Bandeira A,Moon JJ,Bousso P,Albert ML

48-4801 was used in Flow cytometry/Cell sorting to highlight the importance of considering the timing and persistence of antigen presentation for vaccination.

Thu Aug 23 00:00:00 EDT 2012

The Role of TSLP in IL-13-induced atopic march.

Scientific reports

Zhu Z,Oh MH,Yu J,Liu YJ,Zheng T

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Wed Aug 28 00:00:00 EDT 2013

Selective gelatinase blockage ameliorates acute DSS colitis.

European journal of microbiology & immunology

Heimesaat MM,Dunay IR,Fuchs D,Trautmann D,Fischer A,Kühl AA,Loddenkemper C,Batra A,Siegmund B,Krell HW,Bereswill S,Liesenfeld O

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Thu Sep 01 00:00:00 EDT 2011

Suppression and regression of choroidal neovascularization in mice by a novel CCR2 antagonist, INCB3344.

PloS one

Xie P,Kamei M,Suzuki M,Matsumura N,Nishida K,Sakimoto S,Sakaguchi H,Nishida K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Mon Apr 23 00:00:00 EDT 2012

IL-37 is a fundamental inhibitor of innate immunity.

Nature immunology

Nold MF,Nold-Petry CA,Zepp JA,Palmer BE,Bufler P,Dinarello CA

48-4801 was used in Flow cytometry/Cell sorting to determine the function of interleukin 37.

Mon Nov 01 00:00:00 EDT 2010

Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation.

The American journal of pathology

Yang L,Cui H,Wang Z,Zhang B,Ding J,Liu L,Ding HF

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jun 01 00:00:00 EDT 2010

Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation.

The American journal of pathology

Yang L,Cui H,Wang Z,Zhang B,Ding J,Liu L,Ding HF

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Tue Jun 01 00:00:00 EDT 2010

Combination therapy with paricalcitol and trandolapril reduces renal fibrosis in obstructive nephropathy.

Kidney international

Tan X,He W,Liu Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Dec 01 00:00:00 EST 2009

Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.

Hepatology (Baltimore, Md.)

Asahina K,Tsai SY,Li P,Ishii M,Maxson RE,Sucov HM,Tsukamoto H

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Sun Mar 01 00:00:00 EST 2009

Transgenic expression of interleukin-13 in the skin induces a pruritic dermatitis and skin remodeling.

The Journal of investigative dermatology

Zheng T,Oh MH,Oh SY,Schroeder JT,Glick AB,Zhu Z

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Sun Mar 01 00:00:00 EST 2009

Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.

Nature immunology

Lee SW,Park Y,So T,Kwon BS,Cheroutre H,Mittler RS,Croft M

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Flow Cytometry

Fri Aug 01 00:00:00 EDT 2008

Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling.

Journal of the American Society of Nephrology : JASN

Tan X,Wen X,Liu Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Mon Sep 01 00:00:00 EDT 2008

Hepatocyte nuclear factor-1 as marker of epithelial phenotype reveals marrow-derived hepatocytes, but not duct cells, after liver injury in mice.

Stem cells (Dayton, Ohio)

Swenson ES,Guest I,Ilic Z,Mazzeo-Helgevold M,Lizardi P,Hardiman C,Sell S,Krause DS

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Tue Jul 01 00:00:00 EDT 2008

Hepatocyte growth factor exerts its anti-inflammatory action by disrupting nuclear factor-kappaB signaling.

The American journal of pathology

Giannopoulou M,Dai C,Tan X,Wen X,Michalopoulos GK,Liu Y

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Tue Jul 01 00:00:00 EDT 2008

Activation of the Wnt/beta-catenin signaling reporter in developing mouse olfactory nerve layer marks a specialized subgroup of olfactory ensheathing cells.

Developmental dynamics : an official publication of the American Association of Anatomists

Wang YZ,Molotkov A,Song L,Li Y,Pleasure DE,Zhou CJ

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunofluorescence

Sat Nov 01 00:00:00 EDT 2008

Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro.

Journal of leukocyte biology

Geutskens SB,Otonkoski T,Pulkkinen MA,Drexhage HA,Leenen PJ

Sat Oct 01 00:00:00 EDT 2005

Inactivation of the F4/80 glycoprotein in the mouse germ line.

Molecular and cellular biology

Schaller E,Macfarlane AJ,Rupec RA,Gordon S,McKnight AJ,Pfeffer K

Published figure using F4/80 monoclonal antibody (Product # 48-4801-82) in Immunohistochemistry

Fri Nov 01 00:00:00 EST 2002

Bioinformatics

Protein Aliases: Adhesion G protein-coupled receptor E1; Cell surface glycoprotein F4/80; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; lymphocyte antigen 71

View more View less

Gene Aliases: Adgre1; DD7A5-7; EGF-TM7; Emr1; F4/80; Gpf480; Ly71; TM7LN3

View more View less

UniProt ID: (Mouse) Q61549

View more View less

Entrez Gene ID: (Mouse) 13733

View more View less

Function(s)

signal transducer activity transmembrane signaling receptor activity G-protein coupled receptor activity calcium ion binding G-protein coupled receptor

Process(es)

signal transduction cell surface receptor signaling pathway G-protein coupled receptor signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

F4/80 Monoclonal Antibody (BM8), eFluor™ 450, eBioscience™

F4/80 Antibody (48-4801-82) in Flow

Product Details

48-4801-82

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Recommended Isotype Control

Class

Type

Clone

Conjugate

Excitation/Emission Max

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

How to use the Panel Builder

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!