Product References
HMGA2 expression defines a subset of human AML with immature transcriptional signature and vulnerability to G2/M inhibition.
Blood advances
Moison C,Spinella JF,Chagraoui J,Lavallée VP,Lehnertz B,Thiollier C,Boivin I,Mayotte N,MacRae T,Marinier A,Hébert J,Sauvageau G
47-0453-82 was used in Flow cytometry/Cell sorting to suggest that HMGA2 is a key functional determinant in AML and is associated with stem cell features, G2/M status and related drug sensitivity.
Tue Aug 23 00:00:00 EDT 2022
Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.
Science advances
Ma L,Tang Q,Gao X,Lee J,Lei R,Suzuki M,Zheng D,Ito K,Frenette PS,Dawlaty MM
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Fri Mar 04 00:00:00 EST 2022
cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory.
Science immunology
Christian DA,Adams TA,Shallberg LA,Phan AT,Smith TE,Abraha M,Perry J,Ruthel G,Clark JT,Pritchard GH,Aronson LR,Gossa S,McGavern DB,Kedl RM,Hunter CA
47-0453-82 was used in Flow Cytometry to investigate how conventional type 1 dendritic cells (cDC1s) in the peritoneal cavity's omentum coordinate innate responses to microbial challenge and provide secondary signals required for CD8+ T cell expansion and memory formation, particularly after intraperitoneal immunization with Toxoplasma gondii.
Fri Sep 30 00:00:00 EDT 2022
Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade.
Cancer cell
Srivastava S,Furlan SN,Jaeger-Ruckstuhl CA,Sarvothama M,Berger C,Smythe KS,Garrison SM,Specht JM,Lee SM,Amezquita RA,Voillet V,Muhunthan V,Yechan-Gunja S,Pillai SPS,Rader C,Houghton AM,Pierce RH,Gottardo R,Maloney DG,Riddell SR
47-0453-82 was used in Flow Cytometry to test strategies for enhancing efficacy of CAR-T cells targeting the tumor-associated antigen receptor tyrosine kinase-like orphan receptor 1 (ROR1) infiltrating tumors.
Mon Feb 08 00:00:00 EST 2021
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.
Nature immunology
Rivas MA,Meydan C,Chin CR,Challman MF,Kim D,Bhinder B,Kloetgen A,Viny AD,Teater MR,McNally DR,Doane AS,Béguelin W,Fernández MTC,Shen H,Wang X,Levine RL,Chen Z,Tsirigos A,Elemento O,Mason CE,Melnick AM
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling.
Cell reports
Young IC,Wu B,Andricovich J,Chuang ST,Li R,Tzatsos A,Wu RC,Wu MY
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
Ddb1 Is Essential for the Expansion of CD4+ Helper T Cells by Regulating Cell Cycle Progression and Cell Death.
Frontiers in immunology
Yang L,Chen W,Li L,Xiao Y,Fan S,Zhang Q,Xia T,Li M,Hong Y,Zhao T,Li Q,Liu WH,Xiao N
47-0453-82 was used in Flow Cytometry to understand the molecular mechanism underlying the generation of follicular helper T cells.
Mon Dec 20 00:00:00 EST 2021
Ddb1 Is Essential for the Expansion of CD4+ Helper T Cells by Regulating Cell Cycle Progression and Cell Death.
Frontiers in immunology
Yang L,Chen W,Li L,Xiao Y,Fan S,Zhang Q,Xia T,Li M,Hong Y,Zhao T,Li Q,Liu WH,Xiao N
47-0453-82 was used in Flow Cytometry to understand the molecular mechanism underlying the generation of follicular helper T cells.
Mon Dec 20 00:00:00 EST 2021
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell reports
Seydoux E,Wan YH,Feng J,Wall A,Aljedani S,Homad LJ,MacCamy AJ,Weidle C,Gray MD,Brumage L,Taylor JJ,Pancera M,Stamatatos L,McGuire AT
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Tue May 04 00:00:00 EDT 2021
Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes.
Cell reports
Sano T,Kageyama T,Fang V,Kedmi R,Martinez CS,Talbot J,Chen A,Cabrera I,Gorshko O,Kurakake R,Yang Y,Ng C,Schwab SR,Littman DR
47-0453-82 was used in Flow Cytometry to show that intestine-draining mesenteric lymph nodes (MLNs), not intestine proper, are the dominant site of SFB-induced intestinal Th17 cell differentiation.
Tue Aug 24 00:00:00 EDT 2021
Flow cytometric characterization of tissue-resident lymphocytes after murine liver and heart transplantation.
STAR protocols
Prosser A,Dart S,Larma-Cornwall I,Lucas M
47-0453-82 was used in Flow Cytometry to provide a detailed protocol for the isolation of leukocytes, including tissue-resident lymphocytes, from transplanted livers and hearts in mice.
Fri Dec 17 00:00:00 EST 2021
Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus.
Journal of neuroinflammation
Chen KE,Lainez NM,Nair MG,Coss D
47-0453-82 was used in Flow Cytometry to demonstrate a new connection between the adipose tissue and the hypothalamus in obesity that contributes to neuroinflammation and hypothalamic pathologies.
Mon Jun 21 00:00:00 EDT 2021
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy.
Immunity
Milner JJ,Toma C,He Z,Kurd NS,Nguyen QP,McDonald B,Quezada L,Widjaja CE,Witherden DA,Crowl JT,Shaw LA,Yeo GW,Chang JT,Omilusik KD,Goldrath AW
47-0453 was used in Flow cytometry/Cell sorting to identify discrete lineages of intestinal antigen-specific CD8+ T cells, including a Blimp1hiId3lo tissue-resident effector cell population most prominent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1loId3hi tissue-resident memory population that subsequently accumulated at later infection time points.
Tue May 19 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression.
Developmental cell
Wei Q,Nakahara F,Asada N,Zhang D,Gao X,Xu C,Alfieri A,Brodin NP,Zimmerman SE,Mar JC,Guha C,Guo W,Frenette PS
47-0453-82 was used in Flow Cytometry to conclude that SNAI2 is a critical regulator of the transcriptional network maintaining MSPCs by the suppression of osteopontin expression.
Mon Jun 08 00:00:00 EDT 2020
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes.
Frontiers in immunology
Rana A,de Almeida FC,Paico Montero HA,Gonzales Carazas MM,Bortoluci KR,Sad S,Amarante-Mendes GP
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses.
NPJ vaccines
Brar G,Farhat NA,Sukhina A,Lam AK,Kim YH,Hsu T,Tong L,Lin WW,Ware CF,Blackman MA,Sun R,Wu TT
47-0453 was used in Flow cytometry/Cell sorting to provide a framework for effective vaccination against cancer-associated herpesviruses through the elimination of latency and key immune evasion mechanisms from the pathogen.
Thu Nov 05 00:00:00 EST 2020
Engineering monocyte/macrophage-specific glucocerebrosidase expression in human hematopoietic stem cells using genome editing.
Nature communications
Scharenberg SG,Poletto E,Lucot KL,Colella P,Sheikali A,Montine TJ,Porteus MH,Gomez-Ospina N
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Fri Jul 03 00:00:00 EDT 2020
Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal.
Cell reports
Hidalgo San Jose L,Sunshine MJ,Dillingham CH,Chua BA,Kruta M,Hong Y,Hatters DM,Signer RAJ
47-0453 was used in Flow cytometry/Cell sorting to show that hematopoietic stem cells (HSCs) are dependent on low protein synthesis to maintain proteostasis, which promotes their self-renewal.
Tue Jan 07 00:00:00 EST 2020
Use of Busulfan to Condition Mice for Bone Marrow Transplantation.
STAR protocols
Montecino-Rodriguez E,Dorshkind K
47-0453 was used in Flow cytometry/Cell sorting to describe a protocol for the use of busulfan to condition mice for bone marrow transplantation and several of the variables to consider for effective implementation.
Fri Dec 18 00:00:00 EST 2020
TLR9 Sensing of Self-DNA Controls Cell-Mediated Immunity to Listeria Infection via Rapid Conversion of Conventional CD4+ T Cells to Treg.
Cell reports
Dolina JS,Lee J,Griswold RQ,Labarta-Bajo L,Kannan S,Greenbaum JA,Bahia El Idrissi N,Pont MJ,Croft M,Schoenberger SP
47-0453 was used in Flow cytometry/Cell sorting to resolve long-standing questions regarding the conditional requirement for TH amongst pathogens and reveal a remarkable degree of plasticity in the function of CD4+ T cells, which can be quickly converted to Tregin vivo by infection-mediated immune modulation.
Tue Apr 07 00:00:00 EDT 2020
Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK Cells.
Cell reports
Dodard G,Tata A,Erick TK,Jaime D,Miah SMS,Quatrini L,Escalière B,Ugolini S,Vivier E,Brossay L
47-0453 was used in Flow cytometry/Cell sorting to characterize the kinetics and immune response of each of the hepatic NK cell populations to viral challenge and other stimuli.
Tue Jul 07 00:00:00 EDT 2020
Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche.
Immunity
Camara A,Cordeiro OG,Alloush F,Sponsel J,Chypre M,Onder L,Asano K,Tanaka M,Yagita H,Ludewig B,Flacher V,Mueller CG
47-0453 was used in Flow cytometry/Cell sorting to demonstrate that mesenchymal stromal cells created a niche environment with LECs for specialized macrophages to take up residence, complete their differentiation program, and fulfill their immune function.
Tue Jun 18 00:00:00 EDT 2019
A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation.
Immunity
Vacchio MS,Ciucci T,Gao Y,Watanabe M,Balmaceno-Criss M,McGinty MT,Huang A,Xiao Q,McConkey C,Zhao Y,Shetty J,Tran B,Pepper M,Vahedi G,Jenkins MK,McGavern DB,Bosselut R
47-0453-82 was used in Flow Cytometry to identify a transcriptional program that links the CD4+ lineage with Tfh differentiation, a limiting factor for efficient B cell responses.
Tue Sep 17 00:00:00 EDT 2019
IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression.
Cell reports
Elsner RA,Shlomchik MJ
47-0453 was used in Flow cytometry/Cell sorting to investigate the mechanisms of Salmonella enterica serovar Typhimurium (STm) that driving germinal centers suppression.
Tue Nov 26 00:00:00 EST 2019
IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression.
Cell reports
Elsner RA,Shlomchik MJ
47-0453 was used in Flow cytometry/Cell sorting to investigate the mechanisms of Salmonella enterica serovar Typhimurium (STm) that driving germinal centers suppression.
Tue Nov 26 00:00:00 EST 2019
Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection.
Cell reports
Anderson CK,Reilly EC,Lee AY,Brossay L
47-0453 was used in Flow cytometry/Cell sorting to study compensatory mechanisms in immune responses to viruses when classical T cell immunity has been evaded.
Tue Apr 09 00:00:00 EDT 2019
Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation.
Cell reports
Garg G,Muschaweckh A,Moreno H,Vasanthakumar A,Floess S,Lepennetier G,Oellinger R,Zhan Y,Regen T,Hiltensperger M,Peter C,Aly L,Knier B,Palam LR,Kapur R,Kaplan MH,Waisman A,Rad R,Schotta G,Huehn J,Kallies A,Korn T
47-0453 was used in Flow cytometry/Cell sorting to identify a Blimp1-dependent pathway that preserves Treg cell stability in inflamed non-lymphoid tissues.
Tue Feb 12 00:00:00 EST 2019
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.
Cancer cell
Zappasodi R,Budhu S,Hellmann MD,Postow MA,Senbabaoglu Y,Manne S,Gasmi B,Liu C,Zhong H,Li Y,Huang AC,Hirschhorn-Cymerman D,Panageas KS,Wherry EJ,Merghoub T,Wolchok JD
47-0453-82 was used in Flow Cytometry to provide evidence that mouse and human circulating and intra-tumor 4PD1hi inhibit T cell functions in a PD-1/PD-L1 dependent fashion and resemble follicular helper T cell (TFH)-like cells.
Mon Jun 11 00:00:00 EDT 2018
The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.
eLife
Schmidt K,Zhang Q,Tasdogan A,Petzold A,Dahl A,Arneth BM,Slany R,Fehling HJ,Kranz A,Stewart AF,Anastassiadis K
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages.
Scientific reports
Beneke V,Küster F,Neehus AL,Hesse C,Lopez-Rodriguez E,Haake K,Rafiei Hashtchin A,Schott JW,Walter D,Braun A,Wolkers WF,Ackermann M,Lachmann N
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Fri Nov 02 00:00:00 EDT 2018
CART cells are prone to Fas- and DR5-mediated cell death.
Journal for immunotherapy of cancer
Tschumi BO,Dumauthioz N,Marti B,Zhang L,Lanitis E,Irving M,Schneider P,Mach JP,Coukos G,Romero P,Donda A
47-0453 was used in Flow cytometry/Cell sorting to study the effects of in vivo blockade of Fas and DR5 to rescue chimeric antigen receptor T cells from apoptosis.
Fri Jul 13 00:00:00 EDT 2018
Comparison of the MHC I Immunopeptidome Repertoire of B-Cell Lymphoblasts Using Two Isolation Methods.
Proteomics
Lanoix J,Durette C,Courcelles M,Cossette É,Comtois-Marotte S,Hardy MP,Côté C,Perreault C,Thibault P
47-0453-82 was used in Flow cytometry/Cell sorting to compare approaches for the isolation of two different B-cell lymphoblast cell models, and report on the recovery, reproducibility, scalability, and complementarity of identification from each method.
Fri Jun 01 00:00:00 EDT 2018
EPCR expression marks UM171-expanded CD34+ cord blood stem cells.
Blood
Fares I,Chagraoui J,Lehnertz B,MacRae T,Mayotte N,Tomellini E,Aubert L,Roux PP,Sauvageau G
47-0453 was used in Flow cytometry/Cell sorting to study the expression of endothelial protein C receptor as a marker of UM171-expanded human cord blood haematopoietic stem cells.
Thu Jun 22 00:00:00 EDT 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
A type 2 cytokine axis for thymus emigration.
The Journal of experimental medicine
White AJ,Baik S,Parnell SM,Holland AM,Brombacher F,Jenkinson WE,Anderson G
47-0453 was used in Flow cytometry/Cell sorting to show the thymic microenvironment expresses the type 2 IL-4R complex and is functionally responsive to its known ligands, IL-4 and IL-13.
Mon Aug 07 00:00:00 EDT 2017
Sestrin2 Suppresses Classically Activated Macrophages-Mediated Inflammatory Response in Myocardial Infarction through Inhibition of mTORC1 Signaling.
Frontiers in immunology
Yang K,Xu C,Zhang Y,He S,Li D
47-0453 was used in Flow cytometry/Cell sorting to indicate the importance of Sestrin2 for suppression of M1 macrophage-mediated cardiac inflammation after myocardial infarction.
Wed Nov 20 00:00:00 EST 2019
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.
Blood
Pabst C,Bergeron A,Lavallée VP,Yeh J,Gendron P,Norddahl GL,Krosl J,Boivin I,Deneault E,Simard J,Imren S,Boucher G,Eppert K,Herold T,Bohlander SK,Humphries K,Lemieux S,Hébert J,Sauvageau G,Barabé F
47-0453 was used in Flow cytometry/Cell sorting to identify the adhesion G protein-coupled receptor 56 (GPR56) as a novel and stable marker for human leukemia stem cells for the majority of acute myeloid leukemia samples.
Thu Apr 21 00:00:00 EDT 2016
The composition of the microbiota modulates allograft rejection.
The Journal of clinical investigation
Lei YM,Chen L,Wang Y,Stefka AT,Molinero LL,Theriault B,Aquino-Michaels K,Sivan AS,Nagler CR,Gajewski TF,Chong AS,Bartman C,Alegre ML
47-0453 was used in Flow cytometry/Cell sorting to test the influence of host and donor microbiota on skin transplant rejection.
Fri Jul 01 00:00:00 EDT 2016
CD8+ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure.
Journal of autoimmunity
Gravano DM,Al-Kuhlani M,Davini D,Sanders PD,Manilay JO,Hoyer KK
47-0453 was used in Flow cytometry/Cell sorting to investigate whether CD8+ T cells play a non-redundant role in driving bone marrow failure.
Thu Dec 01 00:00:00 EST 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
47-0453 was used in Flow cytometry/Cell sorting to identify a novel pathway of cross-talk between macrophages and dendritic cells.
Sat Oct 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton.
eLife
Yue R,Shen B,Morrison SJ
47-0453 was used in Flow cytometry/Cell sorting to study how Clec11a/Osteolectin maintains the adult skeleton by promoting the differentiation of mesenchymal progenitors into mature osteoblasts.
Tue Dec 13 00:00:00 EST 2016
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
MHC-mismatched mixed chimerism mediates thymic deletion of cross-reactive autoreactive T cells and prevents insulitis in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950)
Racine JJ,Zhang M,Wang M,Morales W,Shen C,Zeng D
47-0453 was used in Flow cytometry/Cell sorting to investigate whether mismatched MHC class II in mixed chimeras mediates deletion of cross-reactive autoreactive thymocytes.
Thu Jan 01 00:00:00 EST 2015
Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis.
Nature communications
Xue J,Sharma V,Hsieh MH,Chawla A,Murali R,Pandol SJ,Habtezion A
Mon May 18 00:00:00 EDT 2015
Determining Leukocyte Origins Using Parabiosis in the PyMT Breast Tumor Model.
Bio-protocol
Franklin RA,Li MO
47-0453 was used in Flow cytometry/Cell sorting to describe the use of parabiosis to define cell ontogeny in a mouse model of breast cancer.
Thu Aug 20 00:00:00 EDT 2015
Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma.
Nature communications
Lee CL,Castle KD,Moding EJ,Blum JM,Williams N,Luo L,Ma Y,Borst LB,Kim Y,Kirsch DG
47-0453 was used in Flow cytometry/Cell sorting to show that total-body irradiation promotes the expansion of a rare population of thymocytes that express oncogenic Kras(G12D).
Thu Sep 24 00:00:00 EDT 2015
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.
Cell
Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Differential requirement for CCR4 and CCR7 during the development of innate and adaptive αβT cells in the adult thymus.
Journal of immunology (Baltimore, Md. : 1950)
Cowan JE,McCarthy NI,Parnell SM,White AJ,Bacon A,Serge A,Irla M,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
47-0453 was used in Flow cytometry/Cell sorting to identify novel roles for CCR7 during intrathymic T cell development, highlighting its importance in enabling multiple αβT cell lineages to access the thymic medulla.
Fri Aug 01 00:00:00 EDT 2014
Identification of small molecules that support human leukemia stem cell activity ex vivo.
Nature methods
Pabst C,Krosl J,Fares I,Boucher G,Ruel R,Marinier A,Lemieux S,Hébert J,Sauvageau G
47-0453-82 was used in Flow cytometry/Cell sorting to conduct a high-throughput chemical screen and identify small molecules that inhibit differentiation and support LSC activity in vitro.
Tue Apr 01 00:00:00 EDT 2014
Circulatory antigen processing by mucosal dendritic cells controls CD8(+) T cell activation.
Immunity
Chang SY,Song JH,Guleng B,Cotoner CA,Arihiro S,Zhao Y,Chiang HS,O'Keeffe M,Liao G,Karp CL,Kweon MN,Sharpe AH,Bhan A,Terhorst C,Reinecker HC
47-0453 was used in Inhibition experiments to conclude that lamina propria CX3CR1(+) DCs facilitate the surveillance of circulatory antigens and induce CD8(+) T cells during mucosal immune responses.
Thu Jan 24 00:00:00 EST 2013
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.
Nature immunology
Reis BS,Rogoz A,Costa-Pinto FA,Taniuchi I,Mucida D
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.
The Journal of experimental medicine
Cowan JE,Parnell SM,Nakamura K,Caamano JH,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
47-0453 was used in Flow cytometry/Cell sorting to demonstrate a differential requirement for the thymic medulla in relation to CD4 conventional and Foxp3(+) thymocyte lineages.
Mon Apr 08 00:00:00 EDT 2013
Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics.
Stem cells (Dayton, Ohio)
Grosselin J,Sii-Felice K,Payen E,Chretien S,Tronik-Le Roux D,Leboulch P
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-leishmania response.
PLoS pathogens
Ribeiro-Gomes FL,Peters NC,Debrabant A,Sacks DL
47-0453 was used in Flow cytometry/Cell sorting to study how exploitation of immunosuppressive effects by L.major following rapid uptake by skin neutrophils allows inhibition of acquired resistance.
Wed Feb 01 00:00:00 EST 2012
In vitro Ag Cross-presentation and in vivo Ag Cross-presentation by Dendritic Cells in the Mouse.
Bio-protocol
Ghosh M,Shapiro LH
Published figure using CD45.1 monoclonal antibody (Product # 47-0453-82) in Flow Cytometry
Thu Dec 20 00:00:00 EST 2012
