Product References
TIM4-TIM1 interaction modulates Th2 pattern inflammation through enhancing SIRT1 expression.
International journal of molecular medicine
Hu T,Fan X,Ma L,Liu J,Chang Y,Yang P,Qiu S,Chen T,Yang L,Liu Z
MCD0405 was used in Flow Cytometry to demonstrate that the interaction of T‚cell immunoglobulin and mucin domain (TIM)4/TIM1 promotes T helper 2-cell proliferation through enhancing silent information regulator 1 expression in mice with nasal allergic rhinitis.
Wed Nov 01 00:00:00 EDT 2017
Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America
Semenkovich NP,Planer JD,Ahern PP,Griffin NW,Lin CY,Gordon JI
MCD0405 was used in flow cytometry to implicate epigenetic modifications in defining microbial community-affiliated functional features of host immune cell lineages
Tue Dec 20 00:00:00 EST 2016
Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis.
PloS one
Van Den Ham KM,Shio MT,Rainone A,Fournier S,Krawczyk CM,Olivier M
MCD0405 was used in Flow Cytometry to determine that the incidence of ECM was markedly reduced in mice treated with iron dextran.
Thu Jan 21 00:00:00 EST 2016
GM-CSF-licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis.
Journal of immunology (Baltimore, Md. : 1950)
Zhou Q,Ho AW,Schlitzer A,Tang Y,Wong KH,Wong FH,Chua YL,Angeli V,Mortellaro A,Ginhoux F,Kemeny DM
MCD0405 was used in Flow cytometry/Cell sorting to identify GM-CSF-licensed CD11b(+) lung DCs as a key component for induction of Th2 responses.
Tue Jul 15 00:00:00 EDT 2014
Complete TCR-α gene locus control region activity in T cells derived in vitro from embryonic stem cells.
Journal of immunology (Baltimore, Md. : 1950)
Lahiji A,Kucerová-Levisohn M,Lovett J,Holmes R,Zúñiga-Pflücker JC,Ortiz BD
MCD0405 was used in flow cytometry to study locus control regions in T cells.
Mon Jul 01 00:00:00 EDT 2013
Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection.
PloS one
Beus JM,Hashmi SS,Selvaraj SA,Duan D,Stempora LL,Monday SA,Cheeseman JA,Hamby KM,Speck SH,Larsen CP,Kirk AD,Kean LS
MCD0405 was used in Flow cytometry/Cell sorting to study changes in CD8(dim) T cell populations in response to a MHV68 rodent model of latent virus-induced heterologous alloimmunity.
Mon Apr 14 00:00:00 EDT 2014
CD4+ Foxp3+ regulatory T cells mediate Toxoplasma gondii-induced T-cell suppression through an IL-2-related mechanism but independently of IL-10.
European journal of immunology
Tenorio EP,Fernández J,Castellanos C,Olguín JE,Saavedra R
MCD0405 was used in Flow cytometry/Cell sorting to study the role of Treg cells in Toxoplasma gondii induced suppression.
Thu Dec 01 00:00:00 EST 2011
Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jones GW,Stumhofer JS,Foster T,Twohig JP,Hertzog P,Topley N,Williams AS,Hunter CA,Jenkins BJ,Wang EC,Jones SA
MCD0405 was used in Flow cytometry/Cell sorting to investigate the relationship between T-cell activation and TL1A responsiveness.
Sat Jan 01 00:00:00 EST 2011
Adverse events post smallpox-vaccination: insights from tail scarification infection in mice with Vaccinia virus.
PloS one
Mota BE,Gallardo-Romero N,Trindade G,Keckler MS,Karem K,Carroll D,Campos MA,Vieira LQ,da Fonseca FG,Ferreira PC,Bonjardim CA,Damon IK,Kroon EG
MCD0405 was used in flow cytometry to determine the components of the host immune system that are sufficient to prevent morbidity/mortality in a murine model of smallpox
Fri Apr 15 00:00:00 EDT 2011
Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
Journal of immunology (Baltimore, Md. : 1950)
Jones GW,McLoughlin RM,Hammond VJ,Parker CR,Williams JD,Malhotra R,Scheller J,Williams AS,Rose-John S,Topley N,Jones SA
MCD0405 was used in Flow cytometry/Cell sorting to report that local control of IL-6 trans signalling regulates the effector characteristics of the T cell infiltrate and promotes the maintenance of IL-17A-secreting CD4(+) T cells.
Mon Feb 15 00:00:00 EST 2010
Chitin induces accumulation in tissue of innate immune cells associated with allergy.
Nature
Reese TA,Liang HE,Tager AM,Luster AD,Van Rooijen N,Voehringer D,Locksley RM
MCD0405 was used in flow cytometry to characterize the effects of chitin on immune responses
Thu May 03 00:00:00 EDT 2007
Inability of memory T cells to induce graft-versus-host disease is a result of an abortive alloresponse.
Blood
Chen BJ,Deoliveira D,Cui X,Le NT,Son J,Whitesides JF,Chao NJ
MCD0405 was used in flow cytometry to propose that memory T cells respond to alloantigens initially but fail to fully develop functionally
Sun Apr 01 00:00:00 EDT 2007
Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous related formin mDia1.
Cancer research
Peng J,Kitchen SM,West RA,Sigler R,Eisenmann KM,Alberts AS
MCD0405 was used in flow cytometry to indicate that defective DRF1 expression or mammalian diaphanous 1 function contributes to myeloid malignancies and suggest mammalian diaphanous 1 as an attractive therapeutic target in human myeloproliferative syndro
Wed Aug 15 00:00:00 EDT 2007
Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors.
Blood
Zhang J,Raper A,Sugita N,Hingorani R,Salio M,Palmowski MJ,Cerundolo V,Crocker PR
MCD0405 was used in flow cytometry to clone and characterize Siglec-H
Mon May 01 00:00:00 EDT 2006
Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Jelley-Gibbs DM,Lepak NM,Yen M,Swain SL
MCD0405 was used in flow cytometry to investigate how antigen exposure affects T cell proliferation and cell death.
Wed Nov 01 00:00:00 EST 2000
