Product References
Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells.
Cancer cell
Sagnella SM,Yang L,Stubbs GE,Boslem E,Martino-Echarri E,Smolarczyk K,Pattison SL,Vanegas N,St Clair E,Clarke S,Boockvar J,MacDiarmid JA,Brahmbhatt H
MCD0417 was used in Flow cytometry/Cell sorting to demonstrate that tumor-targeting EDV nanocells function as an immunotherapeutic by delivering a cytotoxin in conjunction with activation of the immune system.
Mon Mar 16 00:00:00 EDT 2020
A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy.
Oncoimmunology
Casadesús AV,Deligne C,Diallo BK,Sosa K,Josseaume N,Mesa C,León K,Hernández T,Teillaud JL
MCD0417 was used in Flow cytometry/Cell sorting to show that the combination of anti-tumor antibodies and no-alpha mutein is a promising approach to improve the therapeutic effect of these antibodies by potentiating NK/macrophage-mediated innate immunity and the adaptive T-cell response.
Tue Jun 02 00:00:00 EDT 2020
A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy.
Oncoimmunology
Casadesús AV,Deligne C,Diallo BK,Sosa K,Josseaume N,Mesa C,León K,Hernández T,Teillaud JL
MCD0417 was used in Flow cytometry/Cell sorting to show that the combination of anti-tumor antibodies and no-alpha mutein is a promising approach to improve the therapeutic effect of these antibodies by potentiating NK/macrophage-mediated innate immunity and the adaptive T-cell response.
Tue Jun 02 00:00:00 EDT 2020
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.
Nature immunology
Chuprin A,Avin A,Goldfarb Y,Herzig Y,Levi B,Jacob A,Sela A,Katz S,Grossman M,Guyon C,Rathaus M,Cohen HY,Sagi I,Giraud M,McBurney MW,Husebye ES,Abramson J
MCD0417 was used in flow cytometry to determine the role of Sirt1 in regulating the expression of tissue-restricted antigens in medullary thymic epithelial cells.
Wed Jul 01 00:00:00 EDT 2015
Histamine H₂ receptor signaling × environment interactions determine susceptibility to experimental allergic encephalomyelitis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Saligrama N,Case LK,Krementsov DN,Teuscher C
MCD0417 was used in flow cytometry to demonstrate that regulation of encephalitogenic T-cell responses and EAE susceptibility by H2R signaling in CD4(+) T cells is dependent on genetic and environmental interactions.
Tue Apr 01 00:00:00 EDT 2014
Histamine H₂ receptor signaling × environment interactions determine susceptibility to experimental allergic encephalomyelitis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Saligrama N,Case LK,Krementsov DN,Teuscher C
MCD0417 was used in flow cytometry to demonstrate that regulation of encephalitogenic T-cell responses and EAE susceptibility by H2R signaling in CD4(+) T cells is dependent on genetic and environmental interactions.
Tue Apr 01 00:00:00 EDT 2014
Systemic lack of canonical histamine receptor signaling results in increased resistance to autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Saligrama N,Case LK,del Rio R,Noubade R,Teuscher C
MCD0417 was used in flow cytometry to investigate the contribution of histamine on the development of experimental allergic encephalomyelitis.
Mon Jul 15 00:00:00 EDT 2013
The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Cravens PD,Kieseier BC,Hussain R,Herndon E,Arellano B,Ben LH,Timmons BC,Castro-Rojas C,Hartung HP,Hemmer B,Weber MS,Zamvil SS,Stüve O
MCD0417 was used in flow cytometry to test if a differential composition of immune cells within the central nervous system modulates the age-associated susceptibility to autoimmune disease.
Fri May 24 00:00:00 EDT 2013
Histamine H(3) receptor integrates peripheral inflammatory signals in the neurogenic control of immune responses and autoimmune disease susceptibility.
PloS one
Krementsov DN,Wall EH,Martin RA,Subramanian M,Noubade R,Del Rio R,Mawe GM,Bond JP,Poynter ME,Blankenhorn EP,Teuscher C
MCD0417 was used in flow cytometry to characterize Hrh3 polymorphisms between experimental allergic encephalomyelitis-susceptible and resistant mice.
Mon Feb 24 00:00:00 EST 2014
Combinatorial roles for histamine H1-H2 and H3-H4 receptors in autoimmune inflammatory disease of the central nervous system.
European journal of immunology
Saligrama N,Noubade R,Case LK,del Rio R,Teuscher C
MCD0417 was used in flow cytometry to test if combinatorial targeting of histamine receptors is an effective therapy for experimental allergic encephalomyelitis.
Fri Jun 01 00:00:00 EDT 2012
Histamine H4 receptor optimizes T regulatory cell frequency and facilitates anti-inflammatory responses within the central nervous system.
Journal of immunology (Baltimore, Md. : 1950)
del Rio R,Noubade R,Saligrama N,Wall EH,Krementsov DN,Poynter ME,Zachary JF,Thurmond RL,Teuscher C
MCD0417 was used in flow cytometry to investigate the contribution of H(4)R to autoimmunity.
Sun Jan 15 00:00:00 EST 2012
Genetics of experimental allergic encephalomyelitis supports the role of T helper cells in multiple sclerosis pathogenesis.
Annals of neurology
Blankenhorn EP,Butterfield R,Case LK,Wall EH,del Rio R,Diehl SA,Krementsov DN,Saligrama N,Teuscher C
MCD0417 was used in flow cytometry to identify genes involved in multiple sclerosis and experimental allergic encephalomyelitis.
Thu Dec 01 00:00:00 EST 2011
ICAM-5 modulates cytokine/chemokine production in the CNS during the course of herpes simplex virus type 1 infection.
Journal of neuroimmunology
Tse MC,Lane C,Mott K,Onlamoon N,Hsiao HM,Perng GC
MCD0417 was used in Flow cytometry/Cell sorting to suggest that ICAM-5 plays a critical role in modulating chemokine production in the CNS.
Tue Aug 18 00:00:00 EDT 2009
Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation.
Blood
Chen BJ,Cui X,Sempowski GD,Domen J,Chao NJ
MCD0417 was used in flow cytometry to test if higher numbers of hematopoietic stem cells correlate with the speed of immune reconstitution in a congenic transplantation mouse model
Tue Jun 01 00:00:00 EDT 2004
