Product References
The Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Breast Cancer Are Regulated by N-Linked Glycosylation-Dependent Activation of STAT3 and STAT1.
Cells
Erlichman N,Meshel T,Baram T,Abu Raiya A,Horvitz T,Ben-Yaakov H,Ben-Baruch A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Sat Sep 23 00:00:00 EDT 2023
The Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Breast Cancer Are Regulated by N-Linked Glycosylation-Dependent Activation of STAT3 and STAT1.
Cells
Erlichman N,Meshel T,Baram T,Abu Raiya A,Horvitz T,Ben-Yaakov H,Ben-Baruch A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Sat Sep 23 00:00:00 EDT 2023
Canagliflozin primes antitumor immunity by triggering PD-L1 degradation in endocytic recycling.
The Journal of clinical investigation
Ding L,Chen X,Zhang W,Dai X,Guo H,Pan X,Xu Y,Feng J,Yuan M,Gao X,Wang J,Xu X,Li S,Wu H,Cao J,He Q,Yang B
14-5983-82 was used in Immunohistochemistry to show that the FDA-approved sodium-glucose cotransporter-2 (SGLT2) inhibitor canagliflozin dramatically suppressed PD-L1 expression and enhanced T cell-mediated cytotoxicity.
Tue Jan 03 00:00:00 EST 2023
Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells.
PLoS pathogens
Munoz O,Banga R,Schelling R,Procopio FA,Mastrangelo A,Nortier P,Ohmiti K,Daraspe J,Cavassini M,Fenwick C,Perez L,Perreau M
14-5983-82 was used in Immunocytochemistry, Flow Cytometry to show that PD-L1 is incorporated within HIV virions through an active mechanism involving p17 HIV matrix protein.
Fri Jul 01 00:00:00 EDT 2022
Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells.
PLoS pathogens
Munoz O,Banga R,Schelling R,Procopio FA,Mastrangelo A,Nortier P,Ohmiti K,Daraspe J,Cavassini M,Fenwick C,Perez L,Perreau M
14-5983-82 was used in Immunocytochemistry, Flow Cytometry to show that PD-L1 is incorporated within HIV virions through an active mechanism involving p17 HIV matrix protein.
Fri Jul 01 00:00:00 EDT 2022
NKp44-Derived Peptide Used in Combination Stimulates Antineoplastic Efficacy of Targeted Therapeutic Drugs.
International journal of molecular sciences
Iraqi M,Bolel P,Sarkar R,Bhattacharya B,Abu Ahmad M,Edri A,Roisman LC,Elkabets M,Shalata W,Peled N,Porgador A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Mon Nov 14 00:00:00 EST 2022
FOXM1 Inhibition Enhances the Therapeutic Outcome of Lung Cancer Immunotherapy by Modulating PD-L1 Expression and Cell Proliferation.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Madhi H,Lee JS,Choi YE,Li Y,Kim MH,Choi Y,Goh SH
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Immunocytochemistry
Sat Oct 01 00:00:00 EDT 2022
Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes.
Cancers
Erlichman N,Baram T,Meshel T,Morein D,Da'adoosh B,Ben-Baruch A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri Feb 18 00:00:00 EST 2022
GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2.
Frontiers in immunology
Lellahi SM,Azeem W,Hua Y,Gabriel B,Paulsen Rye K,Reikvam H,Kalland KH
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2023
PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells.
Journal for immunotherapy of cancer
Bajor M,Graczyk-Jarzynka A,Marhelava K,Burdzinska A,Muchowicz A,Goral A,Zhylko A,Soroczynska K,Retecki K,Krawczyk M,Klopotowska M,Pilch Z,Paczek L,Malmberg KJ,Wälchli S,Winiarska M,Zagozdzon R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells.
Journal for immunotherapy of cancer
Bajor M,Graczyk-Jarzynka A,Marhelava K,Burdzinska A,Muchowicz A,Goral A,Zhylko A,Soroczynska K,Retecki K,Krawczyk M,Klopotowska M,Pilch Z,Paczek L,Malmberg KJ,Wälchli S,Winiarska M,Zagozdzon R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells.
Journal for immunotherapy of cancer
Bajor M,Graczyk-Jarzynka A,Marhelava K,Burdzinska A,Muchowicz A,Goral A,Zhylko A,Soroczynska K,Retecki K,Krawczyk M,Klopotowska M,Pilch Z,Paczek L,Malmberg KJ,Wälchli S,Winiarska M,Zagozdzon R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells.
Journal for immunotherapy of cancer
Bajor M,Graczyk-Jarzynka A,Marhelava K,Burdzinska A,Muchowicz A,Goral A,Zhylko A,Soroczynska K,Retecki K,Krawczyk M,Klopotowska M,Pilch Z,Paczek L,Malmberg KJ,Wälchli S,Winiarska M,Zagozdzon R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Development of a nanoparticle-based immunotherapy targeting PD-L1 and PLK1 for lung cancer treatment.
Nature communications
Reda M,Ngamcherdtrakul W,Nelson MA,Siriwon N,Wang R,Zaidan HY,Bejan DS,Reda S,Hoang NH,Crumrine NA,Rehwaldt JPC,Bindal A,Mills GB,Gray JW,Yantasee W
14-5983-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to highlight a rational combination strategy to augment existing therapies by utilizing our nanoparticle platform that can load multiple cargo types at once.
Sat Jul 23 00:00:00 EDT 2022
Development of a nanoparticle-based immunotherapy targeting PD-L1 and PLK1 for lung cancer treatment.
Nature communications
Reda M,Ngamcherdtrakul W,Nelson MA,Siriwon N,Wang R,Zaidan HY,Bejan DS,Reda S,Hoang NH,Crumrine NA,Rehwaldt JPC,Bindal A,Mills GB,Gray JW,Yantasee W
14-5983-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to highlight a rational combination strategy to augment existing therapies by utilizing our nanoparticle platform that can load multiple cargo types at once.
Sat Jul 23 00:00:00 EDT 2022
Development of a nanoparticle-based immunotherapy targeting PD-L1 and PLK1 for lung cancer treatment.
Nature communications
Reda M,Ngamcherdtrakul W,Nelson MA,Siriwon N,Wang R,Zaidan HY,Bejan DS,Reda S,Hoang NH,Crumrine NA,Rehwaldt JPC,Bindal A,Mills GB,Gray JW,Yantasee W
14-5983-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to highlight a rational combination strategy to augment existing therapies by utilizing our nanoparticle platform that can load multiple cargo types at once.
Sat Jul 23 00:00:00 EDT 2022
PD-LI promotes rear retraction during persistent cell migration by altering integrin β4 dynamics.
The Journal of cell biology
Wang M,Xiong C,Mercurio AM
14-5983-82 was used in Flow Cytometry to report that PD-L1 has an unanticipated intrinsic function in promoting the dynamics of persistent cell migration.
Mon May 02 00:00:00 EDT 2022
Deciphering the role of miR-187-3p/LRFN1 axis in modulating progression, aerobic glycolysis and immune microenvironment of clear cell renal cell carcinoma.
Discover. Oncology
Xu W,Liu W,Anwaier A,Tian X,Su J,Shi G,Wei S,Qu Y,Zhang H,Ye D
14-5983-82 was used in Immunohistochemistry to reveal the tumor-specific and immunological role of miR-187-3p/LRFN1 axis in the progression and reshaping of tumor immune microenvironment of ccRCC.
Thu Jul 07 00:00:00 EDT 2022
Ruxolitinib reverses checkpoint inhibition by reducing programmed cell death ligand-1 (PD-L1) expression and increases anti-tumour effects of T cells in multiple myeloma.
British journal of haematology
Chen H,Li M,Ng N,Yu E,Bujarski S,Yin Z,Wen M,Hekmati T,Field D,Wang J,Nassir I,Yu J,Huang J,Daniely D,Wang CS,Xu N,Spektor TM,Berenson JR
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Overexpression of PD-L1 is an Independent Predictor for Recurrence in HCC Patients Who Receive Sorafenib Treatment After Surgical Resection.
Frontiers in oncology
Tan Y,Xu Q,Wu Z,Zhang W,Li B,Zhang B,Xu X,Zhang B,Yan K,Song J,Lv T,Yang J,Jiang L,Shi Y,Yang J,Yan L
14-5983-82 was used in Miscellaneous to determine that overexpression of PD-L1 serves as an independent predictor of recurrence in hepatocellular carcinoma patients at high risk of relapse who received adjuvant sorafenib treatment after curative resection.
Sun May 01 00:00:00 EDT 2022
Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages.
Journal of inflammation research
Lai CY,Tseng PC,Chen CL,Satria RD,Wang YT,Lin CF
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Wed Apr 27 00:00:00 EDT 2022
Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition.
Frontiers in endocrinology
Castro-Gutierrez R,Alkanani A,Mathews CE,Michels A,Russ HA
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Thu Feb 10 00:00:00 EST 2022
IL-27 Mediates PD-L1 Expression and Release by Human Mesothelioma Cells.
Cancers
Carbotti G,Dozin B,Martini S,Giordano C,Scordamaglia F,Croce M,Filaci G,Ferrini S,Fabbi M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Mon Aug 09 00:00:00 EDT 2021
Concomitant High Apoptosis Inhibitor of Macrophage (AIM) and Low Prostate-Specific Antigen (PSA) Indicates Activated T Cell-Mediated Anticancer Immunity, Enhance Sensitivity to Pembrolizumab, and Elicit Good Prognosis in Prostate Cancer.
Biomedicines
Bamodu OA,Wang YH,Yeh CT,Ho CH,Chiang YT,Kao WT,Liu CH,Wu CC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Immunohistochemistry
Wed Sep 15 00:00:00 EDT 2021
Concomitant High Apoptosis Inhibitor of Macrophage (AIM) and Low Prostate-Specific Antigen (PSA) Indicates Activated T Cell-Mediated Anticancer Immunity, Enhance Sensitivity to Pembrolizumab, and Elicit Good Prognosis in Prostate Cancer.
Biomedicines
Bamodu OA,Wang YH,Yeh CT,Ho CH,Chiang YT,Kao WT,Liu CH,Wu CC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Immunohistochemistry
Wed Sep 15 00:00:00 EDT 2021
NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1.
Nature communications
Zhang X,Huang X,Xu J,Li E,Lao M,Tang T,Zhang G,Guo C,Zhang X,Chen W,Yadav DK,Bai X,Liang T
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Immunocytochemistry
Tue Jul 27 00:00:00 EDT 2021
Protocol for high-throughput compound screening using flow cytometry in THP-1 cells.
STAR protocols
Spangenberg SH,Zavareh RB,Lairson LL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
Microbe-Mediated Activation of Toll-like Receptor 2 Drives PDL1 Expression in HNSCC.
Cancers
Mann JE,Ludwig ML,Kulkarni A,Scheftz EB,Murray IR,Zhai J,Gensterblum-Miller E,Jiang H,Brenner JC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri Sep 24 00:00:00 EDT 2021
Microbe-Mediated Activation of Toll-like Receptor 2 Drives PDL1 Expression in HNSCC.
Cancers
Mann JE,Ludwig ML,Kulkarni A,Scheftz EB,Murray IR,Zhai J,Gensterblum-Miller E,Jiang H,Brenner JC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri Sep 24 00:00:00 EDT 2021
PD-1 independent of PD-L1 ligation promotes glioblastoma growth through the NFκB pathway.
Science advances
Mirzaei R,Gordon A,Zemp FJ,Kumar M,Sarkar S,Luchman HA,Bellail AC,Hao C,Mahoney DJ,Dunn JF,Bose P,Yong VW
14-5983-82 was used in Immunohistochemistry to point to a critical role for PD-1 in BTICs and uncover a nonimmune resistance mechanism of patients with glioblastoma to PD-1- or PD-L1-blocking therapies.
Fri Nov 05 00:00:00 EDT 2021
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Science immunology
Asano T,Boisson B,Onodi F,Matuozzo D,Moncada-Velez M,Maglorius Renkilaraj MRL,Zhang P,Meertens L,Bolze A,Materna M,Korniotis S,Gervais A,Talouarn E,Bigio B,Seeleuthner Y,Bilguvar K,Zhang Y,Neehus AL,Ogishi M,Pelham SJ,Le Voyer T,Rosain J,Philippot Q,Soler-Palacín P,Colobran R,Martin-Nalda A,Rivière JG,Tandjaoui-Lambiotte Y,Chaïbi K,Shahrooei M,Darazam IA,Olyaei NA,Mansouri D,Hatipoğlu N,Palabiyik F,Ozcelik T,Novelli G,Novelli A,Casari G,Aiuti A,Carrera P,Bondesan S,Barzaghi F,Rovere-Querini P,Tresoldi C,Franco JL,Rojas J,Reyes LF,Bustos IG,Arias AA,Morelle G,Christèle K,Troya J,Planas-Serra L,Schlüter A,Gut M,Pujol A,Allende LM,Rodriguez-Gallego C,Flores C,Cabrera-Marante O,Pleguezuelo DE,de Diego RP,Keles S,Aytekin G,Akcan OM,Bryceson YT,Bergman P,Brodin P,Smole D,Smith CIE,Norlin AC,Campbell TM,Covill LE,Hammarström L,Pan-Hammarström Q,Abolhassani H,Mane S,Marr N,Ata M,Al Ali F,Khan T,Spaan AN,Dalgard CL,Bonfanti P,Biondi A,Tubiana S,Burdet C,Nussbaum R,Kahn-Kirby A,Snow AL,Bustamante J,Puel A,Boisson-Dupuis S,Zhang SY,Béziat V,Lifton RP,Bastard P,Notarangelo LD,Abel L,Su HC,Jouanguy E,Amara A,Soumelis V,Cobat A,Zhang Q,Casanova JL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Thu Aug 19 00:00:00 EDT 2021
EGCG Inhibits Tumor Growth in Melanoma by Targeting JAK-STAT Signaling and Its Downstream PD-L1/PD-L2-PD1 Axis in Tumors and Enhancing Cytotoxic T-Cell Responses.
Pharmaceuticals (Basel, Switzerland)
Ravindran Menon D,Li Y,Yamauchi T,Osborne DG,Vaddi PK,Wempe MF,Zhai Z,Fujita M
14-5983-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to demonstrate that EGCG enhances anti-tumor immune responses by inhibiting JAK-STAT signaling in melanoma.
Tue Oct 26 00:00:00 EDT 2021
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Nature
Heinz LX,Lee J,Kapoor U,Kartnig F,Sedlyarov V,Papakostas K,César-Razquin A,Essletzbichler P,Goldmann U,Stefanovic A,Bigenzahn JW,Scorzoni S,Pizzagalli MD,Bensimon A,Müller AC,King FJ,Li J,Girardi E,Mbow ML,Whitehurst CE,Rebsamen M,Superti-Furga G
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
β-Catenin induces transcriptional expression of PD-L1 to promote glioblastoma immune evasion.
The Journal of experimental medicine
Du L,Lee JH,Jiang H,Wang C,Wang S,Zheng Z,Shao F,Xu D,Xia Y,Li J,Zheng Y,Qian X,Li X,Kim HR,Xing D,Liu P,Lu Z,Lyu J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2020
Protein kinase D3 regulates the expression of the immunosuppressive protein, PD‑L1, through STAT1/STAT3 signaling.
International journal of oncology
Cui B,Chen J,Luo M,Wang L,Chen H,Kang Y,Wang J,Zhou X,Feng Y,Zhang P
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis.
Nature communications
Oulès B,Philippeos C,Segal J,Tihy M,Vietri Rudan M,Cujba AM,Grange PA,Quist S,Natsuga K,Deschamps L,Dupin N,Donati G,Watt FM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2020
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Journal for immunotherapy of cancer
Neuwelt AJ,Kimball AK,Johnson AM,Arnold BW,Bullock BL,Kaspar RE,Kleczko EK,Kwak JW,Wu MH,Heasley LE,Doebele RC,Li HY,Nemenoff RA,Clambey ET
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory.
Cell
Poggio M,Hu T,Pai CC,Chu B,Belair CD,Chang A,Montabana E,Lang UE,Fu Q,Fong L,Blelloch R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Thu Apr 04 00:00:00 EDT 2019
PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways.
Immunity
Zhao Y,Lee CK,Lin CH,Gassen RB,Xu X,Huang Z,Xiao C,Bonorino C,Lu LF,Bui JD,Hui E
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Dec 17 00:00:00 EST 2019
Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer.
International journal of oncology
Nakayama Y,Mimura K,Tamaki T,Shiraishi K,Kua LF,Koh V,Ohmori M,Kimura A,Inoue S,Okayama H,Suzuki Y,Nakazawa T,Ichikawa D,Kono K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Low frequency, weak MCP-1 secretion and exhausted immune status of peripheral monocytes were associated with progression of severe enterovirus A71-infected hand, foot and mouth disease.
Clinical and experimental immunology
Pei X,Fan X,Zhang H,Duan H,Xu C,Xie B,Wang L,Li X,Peng Y,Shen T
14-5983-82 was used in Cell Culture to show disease prognosis in enterovirus A71-associated hand, foot and mouth disease is promoted by count, frequency and levels of MCP-1 secretion.
Sat Jun 01 00:00:00 EDT 2019
Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy.
Cell reports
Celis-Gutierrez J,Blattmann P,Zhai Y,Jarmuzynski N,Ruminski K,Grégoire C,Ounoughene Y,Fiore F,Aebersold R,Roncagalli R,Gstaiger M,Malissen B
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
High PD-L1 Expression Predicts for Worse Outcome of Leukemia Patients with Concomitant NPM1 and FLT3 Mutations.
International journal of molecular sciences
Brodská B,Otevřelová P,Šálek C,Fuchs O,Gašová Z,Kuželová K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Mon Jun 10 00:00:00 EDT 2019
CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not?
Molecules (Basel, Switzerland)
Musielak B,Kocik J,Skalniak L,Magiera-Mularz K,Sala D,Czub M,Stec M,Siedlar M,Holak TA,Plewka J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2019
TLR9 Mediated Tumor-Stroma Interactions in Human Papilloma Virus (HPV)-Positive Head and Neck Squamous Cell Carcinoma Up-Regulate PD-L1 and PD-L2.
Frontiers in immunology
Baruah P,Bullenkamp J,Wilson POG,Lee M,Kaski JC,Dumitriu IE
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Immune Heterogeneity Between Primary Tumors and Corresponding Metastatic Lesions and Response to Platinum Therapy in Primary Ovarian Cancer.
Cancers
Dötzer K,Schlüter F,Schoenberg MB,Bazhin AV,von Koch FE,Schnelzer A,Anthuber S,Grab D,Czogalla B,Burges A,Werner J,Mahner S,Mayer B
14-5983 was used in Immunohistochemistry to show that immune heterogeneity was associated with platinum response and might represent a selection marker for personalized therapy.
Mon Aug 26 00:00:00 EDT 2019
PD-L1 checkpoint blockade delivered by retroviral replicating vector confers anti-tumor efficacy in murine tumor models.
Oncotarget
Mitchell LA,Yagiz K,Hofacre A,Viaud S,Munday AW,Espinoza FL,Mendoza D,Rodriguez-Aguirre ME,Bergqvist S,Haghighi A,Miner MV,Accomando WP,Burrascano C,Gammon D,Gruber HE,Jolly DJ,Lin AH
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in ELISA
Tue Mar 19 00:00:00 EDT 2019
Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.
Cell
Dijkstra KK,Cattaneo CM,Weeber F,Chalabi M,van de Haar J,Fanchi LF,Slagter M,van der Velden DL,Kaing S,Kelderman S,van Rooij N,van Leerdam ME,Depla A,Smit EF,Hartemink KJ,de Groot R,Wolkers MC,Sachs N,Snaebjornsson P,Monkhorst K,Haanen J,Clevers H,Schumacher TN,Voest EE
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension.
Circulation research
Tamosiuniene R,Manouvakhova O,Mesange P,Saito T,Qian J,Sanyal M,Lin YC,Nguyen LP,Luria A,Tu AB,Sante JM,Rabinovitch M,Fitzgerald DJ,Graham BB,Habtezion A,Voelkel NF,Aurelian L,Nicolls MR
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri Jun 08 00:00:00 EDT 2018
Exhaustion of the CD8+ T Cell Compartment in Patients with Mutations in Phosphoinositide 3-Kinase Delta.
Frontiers in immunology
Wentink MWJ,Mueller YM,Dalm VASH,Driessen GJ,van Hagen PM,van Montfrans JM,van der Burg M,Katsikis PD
14-5983 was used in Functional assays to study exhaustion of the CD8+ T cell compartment in activated phosphoinositide 3-kinase delta syndrome patients and compare them with healthy controls and HIV patients.
Mon Jun 24 00:00:00 EDT 2019
Specific expression of PD-L1 in RELA-fusion supratentorial ependymoma: Implications for PD-1-targeted therapy.
Pediatric blood & cancer
Witt DA,Donson AM,Amani V,Moreira DC,Sanford B,Hoffman LM,Handler MH,Levy JMM,Jones KL,Nellan A,Foreman NK,Griesinger AM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
ATM‑JAK‑PD‑L1 signaling pathway inhibition decreases EMT and metastasis of androgen‑independent prostate cancer.
Molecular medicine reports
Zhang L,Xu LJ,Zhu J,Li J,Xue BX,Gao J,Sun CY,Zang YC,Zhou YB,Yang DR,Shan YX
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Western Blot
Tue May 01 00:00:00 EDT 2018
Disruption of PD-1 Enhanced the Anti-tumor Activity of Chimeric Antigen Receptor T Cells Against Hepatocellular Carcinoma.
Frontiers in pharmacology
Guo X,Jiang H,Shi B,Zhou M,Zhang H,Shi Z,Du G,Luo H,Wu X,Wang Y,Sun R,Li Z
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Thu Sep 28 00:00:00 EDT 2023
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Immunofluorescence
Wed Mar 28 00:00:00 EDT 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Immunofluorescence
Wed Mar 28 00:00:00 EDT 2018
Similarities and differences between helminth parasites and cancer cell lines in shaping human monocytes: Insights into parallel mechanisms of immune evasion.
PLoS neglected tropical diseases
Narasimhan PB,Akabas L,Tariq S,Huda N,Bennuru S,Sabzevari H,Hofmeister R,Nutman TB,Tolouei Semnani R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
PD-L1 expression in medulloblastoma: an evaluation by subgroup.
Oncotarget
Martin AM,Nirschl CJ,Polanczyk MJ,Bell WR,Nirschl TR,Harris-Bookman S,Phallen J,Hicks J,Martinez D,Ogurtsova A,Xu H,Sullivan LM,Meeker AK,Raabe EH,Cohen KJ,Eberhart CG,Burger PC,Santi M,Taube JM,Pardoll DM,Drake CG,Lim M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Apr 10 00:00:00 EDT 2018
PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse.
Journal of hematology & oncology
Zheng B,Ren T,Huang Y,Sun K,Wang S,Bao X,Liu K,Guo W
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Feb 06 00:00:00 EST 2018
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Journal of experimental & clinical cancer research : CR
Xu L,Zhang Y,Tian K,Chen X,Zhang R,Mu X,Wu Y,Wang D,Wang S,Liu F,Wang T,Zhang J,Liu S,Zhang Y,Tu C,Liu H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Mon Oct 29 00:00:00 EDT 2018
Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells.
Cell reports
Zhao Y,Harrison DL,Song Y,Ji J,Huang J,Hui E
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Jul 10 00:00:00 EDT 2018
A versatile T cell-based assay to assess therapeutic antigen-specific PD-1-targeted approaches.
Oncotarget
Versteven M,Van den Bergh JMJ,Broos K,Fujiki F,Campillo-Davo D,De Reu H,Morimoto S,Lecocq Q,Keyaerts M,Berneman Z,Sugiyama H,Van Tendeloo VFI,Breckpot K,Lion E
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Neutralization
Tue Jun 12 00:00:00 EDT 2018
Amphotericin B suppresses M2 phenotypes and B7-H1 expression in macrophages to prevent Raji cell proliferation.
BMC cancer
Zhang J,Cao D,Yu S,Chen L,Wei D,Shen C,Zhuang L,Wang Q,Xu X,Tong Y
14-5983 was used in Flow cytometry/Cell sorting to determine the role of macrophages in Burkitt's lymphoma.
Thu Apr 26 00:00:00 EDT 2018
Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.
Immunity
Coelho MA,de Carné Trécesson S,Rana S,Zecchin D,Moore C,Molina-Arcas M,East P,Spencer-Dene B,Nye E,Barnouin K,Snijders AP,Lai WS,Blackshear PJ,Downward J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Dec 19 00:00:00 EST 2017
Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro.
Molecular therapy. Nucleic acids
Lin AH,Twitty CG,Burnett R,Hofacre A,Mitchell LA,Espinoza FL,Gruber HE,Jolly DJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri Mar 17 00:00:00 EDT 2017
Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression.
Stem cells (Dayton, Ohio)
Davies LC,Heldring N,Kadri N,Le Blanc K
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Characterization and Purification of Neoplastic Cells of Nodular Lymphocyte Predominant Hodgkin Lymphoma from Lymph Nodes by Flow Cytometry and Flow Cytometric Cell Sorting.
The American journal of pathology
Fromm JR,Thomas A,Wood BL
14598382 was used in flow cytometry to document and describe lymphocyte predominant cells from lymph nodes involved in nodular lymphocyte predominant Hodgkin lymphoma
Wed Feb 01 00:00:00 EST 2017
Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.
Oncoimmunology
Layer JP,Kronmüller MT,Quast T,van den Boorn-Konijnenberg D,Effern M,Hinze D,Althoff K,Schramm A,Westermann F,Peifer M,Hartmann G,Tüting T,Kolanus W,Fischer M,Schulte J,Hölzel M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice.
The Journal of biological chemistry
Dimitrov V,Bouttier M,Boukhaled G,Salehi-Tabar R,Avramescu RG,Memari B,Hasaj B,Lukacs GL,Krawczyk CM,White JH
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Western Blot
Fri Dec 15 00:00:00 EST 2017
Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice.
The Journal of biological chemistry
Dimitrov V,Bouttier M,Boukhaled G,Salehi-Tabar R,Avramescu RG,Memari B,Hasaj B,Lukacs GL,Krawczyk CM,White JH
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Western Blot
Fri Dec 15 00:00:00 EST 2017
Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice.
The Journal of biological chemistry
Dimitrov V,Bouttier M,Boukhaled G,Salehi-Tabar R,Avramescu RG,Memari B,Hasaj B,Lukacs GL,Krawczyk CM,White JH
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Western Blot
Fri Dec 15 00:00:00 EST 2017
PD-L1/PD-1 expression and tumor-infiltrating lymphocytes in conjunctival melanoma.
Oncotarget
Cao J,Brouwer NJ,Richards KE,Marinkovic M,van Duinen S,Hurkmans D,Verdegaal EME,Jordanova ES,Jager MJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells.
PloS one
Hock BD,MacPherson SA,McKenzie JL
14-5983 was used in Inhibition experiments to raise the possibility that these compounds may provide a useful therapeutic adjunct by reducing immuno-suppression within the tumor micro-environment of CLL.
Tue Aug 22 00:00:00 EDT 2017
Tolerogenic IDO(+) Dendritic Cells Are Induced by PD-1-Expressing Mast Cells.
Frontiers in immunology
Rodrigues CP,Ferreira AC,Pinho MP,de Moraes CJ,Bergami-Santos PC,Barbuto JA
14-5983 was used in Blocking experiments to show that direct cell contact between immature monocyte-derived DCs (iDCs) and MC bends DCs toward tolerance induction.
Tue Feb 02 00:00:00 EST 2016
Regulatory IgDhi B Cells Suppress T Cell Function via IL-10 and PD-L1 during Progressive Visceral Leishmaniasis.
Journal of immunology (Baltimore, Md. : 1950)
Schaut RG,Lamb IM,Toepp AJ,Scott B,Mendes-Aguiar CO,Coutinho JF,Jeronimo SM,Wilson ME,Harty JT,Waldschmidt TJ,Petersen CA
14-5983 was used in Blocking experiments to highlight a novel regulatory B cell that may precipitate T cell exhaustion during visceral leishmaniasis.
Sun May 15 00:00:00 EDT 2016
PD-L1 expression in human cancers and its association with clinical outcomes.
OncoTargets and therapy
Wang X,Teng F,Kong L,Yu J
14-5983 was used in Immunohistochemistry to examine the expression of PD-L1 in human cancers, and assess its influence on disease outcome.
Tue Aug 30 00:00:00 EDT 2016
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Expression of programmed death 1 ligand 1 on periodontal tissue cells as a possible protective feedback mechanism against periodontal tissue destruction.
Molecular medicine reports
Zhang J,Wang CM,Zhang P,Wang X,Chen J,Yang J,Lu W,Zhou W,Yuan W,Feng Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Ly6Chi monocytes regulate T cell responses in viral hepatitis.
JCI insight
Zhu J,Chen H,Huang X,Jiang S,Yang Y
14-5983 was used in Flow cytometry/Cell sorting to study the mechanism by which adenoviral infection induces recruitment of Ly6Chi monocytes to the liver.
Thu Oct 20 00:00:00 EDT 2016
Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53.
Science (New York, N.Y.)
Yoon KW,Byun S,Kwon E,Hwang SY,Chu K,Hiraki M,Jo SH,Weins A,Hakroush S,Cebulla A,Sykes DB,Greka A,Mundel P,Fisher DE,Mandinova A,Lee SW
14-5983 was used in Flow cytometry/Cell sorting to reveal that p53-induced expression of death domain 1α regulates the efficient clearance of dead cells and proper immune tolerance.
Fri Jul 31 00:00:00 EDT 2015
Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53.
Science (New York, N.Y.)
Yoon KW,Byun S,Kwon E,Hwang SY,Chu K,Hiraki M,Jo SH,Weins A,Hakroush S,Cebulla A,Sykes DB,Greka A,Mundel P,Fisher DE,Mandinova A,Lee SW
14-5983 was used in Flow cytometry/Cell sorting to reveal that p53-induced expression of death domain 1α regulates the efficient clearance of dead cells and proper immune tolerance.
Fri Jul 31 00:00:00 EDT 2015
Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance.
Prostate cancer and prostatic diseases
Martin AM,Nirschl TR,Nirschl CJ,Francica BJ,Kochel CM,van Bokhoven A,Meeker AK,Lucia MS,Anders RA,DeMarzo AM,Drake CG
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance.
Prostate cancer and prostatic diseases
Martin AM,Nirschl TR,Nirschl CJ,Francica BJ,Kochel CM,van Bokhoven A,Meeker AK,Lucia MS,Anders RA,DeMarzo AM,Drake CG
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Programmed death ligand 1 on Burkholderia pseudomallei-infected human polymorphonuclear neutrophils impairs T cell functions.
Journal of immunology (Baltimore, Md. : 1950)
Buddhisa S,Rinchai D,Ato M,Bancroft GJ,Lertmemongkolchai G
14-5983 was used in Blocking experiments to examine the interaction of PMNs and T cells in response to infection with Burkholderia pseudomallei, the causative agent of human melioidosis.
Fri May 01 00:00:00 EDT 2015
Assays for predicting and monitoring responses to lung cancer immunotherapy.
Cancer biology & medicine
Teixidó C,Karachaliou N,González-Cao M,Morales-Espinosa D,Rosell R
14-5983 was used in Immunohistochemistry to show that the interaction blockade of PD-1 and PD-L1 demonstrated promising activity and antitumor efficacy in early phase clinical trials for advanced solid tumors such as non-small cell lung cancer.
Mon Jun 01 00:00:00 EDT 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Sep 08 00:00:00 EDT 2015
IL-27 induces the expression of IDO and PD-L1 in human cancer cells.
Oncotarget
Carbotti G,Barisione G,Airoldi I,Mezzanzanica D,Bagnoli M,Ferrero S,Petretto A,Fabbi M,Ferrini S
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Tue Dec 22 00:00:00 EST 2015
Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions.
F1000Research
Gulati N,Suárez-Fariñas M,Correa da Rosa J,Krueger JG
14-5983 was used in Immunohistochemistry on frozen tissues to provide a tractable model for the primary discovery of pathways potentially involved in immune regulation in peripheral tissues.
Mon Aug 03 00:00:00 EDT 2015
Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153.
PloS one
Baban B,Liu JY,Qin X,Weintraub NL,Mozaffari MS
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Immunohistochemistry
Tue Apr 12 00:00:00 EDT 2016
Immune-escape markers in relation to clinical outcome of advanced melanoma patients following immunotherapy.
Cancer immunology research
Tjin EP,Krebbers G,Meijlink KJ,van de Kasteele W,Rosenberg EH,Sanders J,Nederlof PM,van de Wiel BA,Haanen JB,Melief CJ,Vyth-Dreese FA,Luiten RM
14-5983 was used in Immunohistochemistry on frozen tissues to indicate a more prominent role for T-cell infiltration and activation in tumour tissue than immune-escape mechanisms for clinical outcomes in advanced melanoma patients.
Sun Jun 01 00:00:00 EDT 2014
Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment.
Cancer science
Mimura K,Kua LF,Shiraishi K,Kee Siang L,Shabbir A,Komachi M,Suzuki Y,Nakano T,Yong WP,So J,Kono K
14-5983 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which HLA class I and PD-L1 are regulated by MAPK inhibitors and interferon-γ.
Wed Oct 01 00:00:00 EDT 2014
Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Sznol M,Chen L
14-5983 was used in Immunohistochemistry on frozen tissues to investigate the effect of using antagonist antibodies to PD-1 and B7-H1 in advanced human cancer.
Fri Mar 01 00:00:00 EST 2013
Inhibiting the programmed death 1 pathway rescues Mycobacterium tuberculosis-specific interferon γ-producing T cells from apoptosis in patients with pulmonary tuberculosis.
The Journal of infectious diseases
Singh A,Mohan A,Dey AB,Mitra DK
14-5983 was used in Flow cytometry/Cell sorting to examine the role of the programmed death 1 pathway in downregulating the T-cell response among patients with pulmonary tuberculosis.
Thu Aug 15 00:00:00 EDT 2013
Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function.
Journal of immunology (Baltimore, Md. : 1950)
Esch KJ,Juelsgaard R,Martinez PA,Jones DE,Petersen CA
14-5983 was used in Blocking experiments to demonstrate that concurrent CD4+ and CD8+ T cell exhaustion is mediated by elevated surface expression of PD-1.
Sun Dec 01 00:00:00 EST 2013
Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine.
Oncotarget
Wrangle J,Wang W,Koch A,Easwaran H,Mohammad HP,Vendetti F,Vancriekinge W,Demeyer T,Du Z,Parsana P,Rodgers K,Yen RW,Zahnow CA,Taube JM,Brahmer JR,Tykodi SS,Easton K,Carvajal RD,Jones PA,Laird PW,Weisenberger DJ,Tsai S,Juergens RA,Topalian SL,Rudin CM,Brock MV,Pardoll D,Baylin SB
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
NF-κB plays a key role in inducing CD274 expression in human monocytes after lipopolysaccharide treatment.
PloS one
Huang G,Wen Q,Zhao Y,Gao Q,Bai Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in ChIP assay
Tue Oct 22 00:00:00 EDT 2013
NF-κB plays a key role in inducing CD274 expression in human monocytes after lipopolysaccharide treatment.
PloS one
Huang G,Wen Q,Zhao Y,Gao Q,Bai Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in ChIP assay
Tue Oct 22 00:00:00 EDT 2013
Foxp3+ regulatory T cells among tuberculosis patients: impact on prognosis and restoration of antigen specific IFN-γ producing T cells.
PloS one
Singh A,Dey AB,Mohan A,Sharma PK,Mitra DK
14-5983 was used in Blocking experiments to investigate the impact of Tregs and PD-1 molecules on the severity of human tuberculosis.
Wed Mar 06 00:00:00 EST 2013
TNF-α and TGF-β counter-regulate PD-L1 expression on monocytes in systemic lupus erythematosus.
Scientific reports
Ou JN,Wiedeman AE,Stevens AM
14-5983 was used in Flow cytometry/Cell sorting to investigate the mechanism for PD-L1 dysregulation on lupus monocytes.
Fri Apr 12 00:00:00 EDT 2013
Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation.
Cell stem cell
Zheng J,Umikawa M,Zhang S,Huynh H,Silvany R,Chen BP,Chen L,Zhang CC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2011
Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation.
Cell stem cell
Zheng J,Umikawa M,Zhang S,Huynh H,Silvany R,Chen BP,Chen L,Zhang CC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2011
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Wed Dec 07 00:00:00 EST 2011
Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression.
Cancer research
Banerjee S,Lin CF,Skinner KA,Schiffhauer LM,Peacock J,Hicks DG,Redmond EM,Morrow D,Huston A,Shayne M,Langstein HN,Miller-Graziano CL,Strickland J,O'Donoghue L,De AK
14-5983 was used in Immunohistochemistry on paraffin embedded tissues to investigate the role of Hsp27 in breast cancer, showing that Hsp27 differentiates tolerogenic macrophages.
Sat Jan 15 00:00:00 EST 2011
Tumor cell programmed death ligand 1-mediated T cell suppression is overcome by coexpression of CD80.
Journal of immunology (Baltimore, Md. : 1950)
Haile ST,Bosch JJ,Agu NI,Zeender AM,Somasundaram P,Srivastava MK,Britting S,Wolf JB,Ksander BR,Ostrand-Rosenberg S
14-5983 was used in Western Blotting to demonstrate that CD80 transfected human tumour cells block PDL1-mediated immune suppression by tumour cells and restores T cell activation.
Wed Jun 15 00:00:00 EDT 2011
HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Muthumani K,Shedlock DJ,Choo DK,Fagone P,Kawalekar OU,Goodman J,Bian CB,Ramanathan AA,Atman P,Tebas P,Chattergoon MA,Choo AY,Weiner DB
14-5983 was used in Flow cytometry/Cell sorting to investigate the regulation of the PD-1 pathway during HIV infection.
Thu Sep 15 00:00:00 EDT 2011
Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma.
World journal of gastroenterology
Wang BJ,Bao JJ,Wang JZ,Wang Y,Jiang M,Xing MY,Zhang WG,Qi JY,Roggendorf M,Lu MJ,Yang DL
14-5983 was used in Immunohistochemistry to investigate the expression of PD-1, PD-L1 and PD-L2 in liver tissues in the context of chronic hepatitis and hepatocellular carcinoma.
Thu Jul 28 00:00:00 EDT 2011
Activated memory B cells may function as antigen-presenting cells in the joints of children with juvenile idiopathic arthritis.
Arthritis and rheumatism
Morbach H,Wiegering V,Richl P,Schwarz T,Suffa N,Eichhorn EM,Eyrich M,Girschick HJ
14-5983 was used in Flow cytometry/Cell sorting to investigate whether synovial B cells in juvenile idiopathic arthritis display features of antigen-presenting cells.
Tue Nov 01 00:00:00 EDT 2011
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody.
Blood
Benson DM,Bakan CE,Mishra A,Hofmeister CC,Efebera Y,Becknell B,Baiocchi RA,Zhang J,Yu J,Smith MK,Greenfield CN,Porcu P,Devine SM,Rotem-Yehudar R,Lozanski G,Byrd JC,Caligiuri MA
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2010
Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer.
Proceedings of the National Academy of Sciences of the United States of America
Matsuzaki J,Gnjatic S,Mhawech-Fauceglia P,Beck A,Miller A,Tsuji T,Eppolito C,Qian F,Lele S,Shrikant P,Old LJ,Odunsi K
14-5983-82 was used in Inhibition Assays to examine in vivo tumour-tolerance mechanisms relating to inhibitory immune checkpoints.
Tue Apr 27 00:00:00 EDT 2010
Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule.
Breast cancer research : BCR
Ghebeh H,Lehe C,Barhoush E,Al-Romaih K,Tulbah A,Al-Alwan M,Hendrayani SF,Manogaran P,Alaiya A,Al-Tweigeri T,Aboussekhra A,Dermime S
14-5983 was used in Western Blotting to investigate the effect of neoadjuvant chemotherapy on the expression of B7-H1 in breast cancer cells.
Tue Mar 01 00:00:00 EST 2011
Mechanisms of immune suppression for CD8+ T cells by human corneal endothelial cells via membrane-bound TGFbeta.
Investigative ophthalmology & visual science
Yamada Y,Sugita S,Horie S,Yamagami S,Mochizuki M
14-5983 was used in Blocking experiments to determine whether CD8(+) T cells in vitro are suppressed or converted into regulators by human corneal endothelial cells.
Sat May 01 00:00:00 EDT 2010
B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders.
Blood
Wilcox RA,Feldman AL,Wada DA,Yang ZZ,Comfere NI,Dong H,Kwon ED,Novak AJ,Markovic SN,Pittelkow MR,Witzig TE,Ansell SM
14-5983-82 was used in Functional assay to implicate B7-H1 in the suppression of host immunity in T-cell lymphoproliferative disorders and suggest that the targeting of B7-H1 may represent a novel therapeutic approach.
Thu Sep 03 00:00:00 EDT 2009
Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1.
The Journal of experimental medicine
Kuang DM,Zhao Q,Peng C,Xu J,Zhang JP,Wu C,Zheng L
14-5983 was used in Immunohistochemistry to suggest PD-L1 expression on activated monocytes as a novel mechanism by which the proinflammatory response is linked to immune tolerance in the tumour milieu.
Mon Jun 08 00:00:00 EDT 2009
PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients.
Leukemia
Kozako T,Yoshimitsu M,Fujiwara H,Masamoto I,Horai S,White Y,Akimoto M,Suzuki S,Matsushita K,Uozumi K,Tei C,Arima N
14-5983 was used in Blocking experiments to determine whether the PD-1/PD-L1 pathway could be involved in the establishment of persistent HTLV-1 infections.
Sun Feb 01 00:00:00 EST 2009
MicroRNA-513 regulates B7-H1 translation and is involved in IFN-gamma-induced B7-H1 expression in cholangiocytes.
Journal of immunology (Baltimore, Md. : 1950)
Gong AY,Zhou R,Hu G,Li X,Splinter PL,O'Hara SP,LaRusso NF,Soukup GA,Dong H,Chen XM
14-5983 was used in Western Blotting to show that resting human cholangiocytes in culture express B7-H1 mRNA, but not B7-H1 protein.
Sun Feb 01 00:00:00 EST 2009
Costimulatory pathways in multiple sclerosis: distinctive expression of PD-1 and PD-L1 in patients with different patterns of disease.
Journal of immunology (Baltimore, Md. : 1950)
Trabattoni D,Saresella M,Pacei M,Marventano I,Mendozzi L,Rovaris M,Caputo D,Borelli M,Clerici M
14-5983 was used in Blocking experiments to indicate the important role of the PD-1/PD-L1 costimulatory pathway in modulating disease activity in multiple sclerosis.
Thu Oct 15 00:00:00 EDT 2009
PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients.
Journal of immunology (Baltimore, Md. : 1950)
Fourcade J,Kudela P,Sun Z,Shen H,Land SR,Lenzner D,Guillaume P,Luescher IF,Sander C,Ferrone S,Kirkwood JM,Zarour HM
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 14-5983-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2009
Human corneal endothelial cells expressing programmed death-ligand 1 (PD-L1) suppress PD-1+ T helper 1 cells by a contact-dependent mechanism.
Investigative ophthalmology & visual science
Sugita S,Usui Y,Horie S,Futagami Y,Yamada Y,Ma J,Kezuka T,Hamada H,Usui T,Mochizuki M,Yamagami S
14-5983 was used in Flow cytometry/Cell sorting to show that the corneal endothelium may induce peripheral immune tolerance of the anterior chamber of the eye.
Thu Jan 01 00:00:00 EST 2009
Human corneal endothelial cells expressing programmed death-ligand 1 (PD-L1) suppress PD-1+ T helper 1 cells by a contact-dependent mechanism.
Investigative ophthalmology & visual science
Sugita S,Usui Y,Horie S,Futagami Y,Yamada Y,Ma J,Kezuka T,Hamada H,Usui T,Mochizuki M,Yamagami S
14-5983 was used in Flow cytometry/Cell sorting to show that the corneal endothelium may induce peripheral immune tolerance of the anterior chamber of the eye.
Thu Jan 01 00:00:00 EST 2009
Interaction of human PD-L1 and B7-1.
Molecular immunology
Butte MJ,Peña-Cruz V,Kim MJ,Freeman GJ,Sharpe AH
14-5983 was used in Flow cytometry/Cell sorting to investigate whether human B7-1 and PD-L1 can participate in a similar interaction as murine B7-1 and PD-L1 do, showing that there is interaction of human PD-L1 and B7-1.
Fri Aug 01 00:00:00 EDT 2008
Interaction of human PD-L1 and B7-1.
Molecular immunology
Butte MJ,Peña-Cruz V,Kim MJ,Freeman GJ,Sharpe AH
14-5983 was used in Flow cytometry/Cell sorting to investigate whether human B7-1 and PD-L1 can participate in a similar interaction as murine B7-1 and PD-L1 do, showing that there is interaction of human PD-L1 and B7-1.
Fri Aug 01 00:00:00 EDT 2008
The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors.
Neoplasia (New York, N.Y.)
Ghebeh H,Mohammed S,Al-Omair A,Qattan A,Lehe C,Al-Qudaihi G,Elkum N,Alshabanah M,Bin Amer S,Tulbah A,Ajarim D,Al-Tweigeri T,Dermime S
14-5983 was used in Immunohistochemistry to investigate the expression of the B7-H1 molecule in breast cancer specimens and study its correlation with patients' clinicopathological parameters.
Wed Mar 01 00:00:00 EST 2006
Expression of B7-H1 in inflammatory renal tubular epithelial cells.
Nephron. Experimental nephrology
Chen Y,Zhang J,Li J,Zou L,Zhao T,Tang Y,Wu Y
Fri Apr 21 00:00:00 EDT 2006
Expression of B7-H1 in inflammatory renal tubular epithelial cells.
Nephron. Experimental nephrology
Chen Y,Zhang J,Li J,Zou L,Zhao T,Tang Y,Wu Y
Fri Apr 21 00:00:00 EDT 2006
Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ohigashi Y,Sho M,Yamada Y,Tsurui Y,Hamada K,Ikeda N,Mizuno T,Yoriki R,Kashizuka H,Yane K,Tsushima F,Otsuki N,Yagita H,Azuma M,Nakajima Y
Fri Apr 15 00:00:00 EDT 2005
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.jpg?time=20220826?time=20220826 "CD274 (PD-L1, B7-H1) Antibody (14-5983-82) in Flow")
.jpg?time=20220826?time=20220826 "CD274 (PD-L1, B7-H1) Antibody (14-5983-82) in Flow")
