Invitrogen

CD11b Monoclonal Antibody (M1/70), Biotin, eBioscience™

FIGURE: 1 / 97

CD11b Antibody (13-0112-82) in Flow

Staining of C57BL/6 bone marrow cells with 0.06 µg of Biotin Rat IgG2b kappa Isotype Control Biotin (Product # 13-4031-82) (open histogram) or 0.06 µg of Anti-Mouse CD11b Biotin (filled histogram) followed by Streptavidin PE (Product # 12-4317-87). Cells in the lymphoid (left) or myeloid (right) populations were used for analysis.

CD11b Antibody in Western Blot, Immunoprecipitation (WB, IP)

CD11b Antibody in Immunohistochemistry (IHC)

CD11b Antibody in Immunocytochemistry (ICC/IF)

CD11b Antibody in Immunocytochemistry, Immunohistochemistry (PFA fixed) (ICC/IF, IHC (PFA))

CD11b Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)

CD11b Antibody in Immunohistochemistry (Frozen) (IHC (F))

CD11b Antibody in Immunohistochemistry, Flow Cytometry (IHC, Flow)

CD11b Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Product Image Gallery

Product Details

13-0112-82

Applications

Tested Dilution

Publications

Western Blot (WB)

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 45 publications 45 publications

Immunohistochemistry (PFA fixed) (IHC (PFA))

View 4 publications 4 publications

Immunohistochemistry (Frozen) (IHC (F))

Assay-Dependent

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

View 19 publications 19 publications

Flow Cytometry (Flow)

0.125 µg/test

View 318 publications 318 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Neutralization (Neu)

View 2 publications 2 publications

Functional Assay (Functional)

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 11 publications 11 publications

Product Specifications

Species Reactivity

Mouse

Published species

Fish, Human, Mouse

Host/Isotype

Rat / IgG2b, kappa

Recommended Isotype Control

Rat IgG2b kappa Isotype Control (eB149/10H5), Biotin, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

M1/70

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_466359

Product Specific Information

Description: The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaMbeta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.

Applications Reported: This M1/70 antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining of frozen tissue sections. The M1/70 clone is not recommended for immunohistochemical staining of formalin-fixed paraffin embedded tissue.

Applications Tested: The M1/70 antibody has been tested by flow cytometric analysis of mouse splenocytes or bone marrow cells. This can be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Deciphering the mechanism of Peptostreptococcus anaerobius-induced chemoresistance in colorectal cancer: the important roles of MDSC recruitment and EMT activation.

Frontiers in immunology

Gu J,Lv X,Li W,Li G,He X,Zhang Y,Shi L,Zhang X

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Oct 03 00:00:00 EDT 2023

Exogenous IL-10 posttreatment along with TLR4 and TNFR1 blockade improves tissue antioxidant status by modulating sepsis-induced macrophage polarization.

Journal of applied toxicology : JAT

Sawoo R,Dey R,Ghosh R,Bishayi B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2023

Gene deletion of long-chain acyl-CoA synthetase 4 attenuates xenobiotic chemical-induced lung injury via the suppression of lipid peroxidation.

Redox biology

Tomitsuka Y,Imaeda H,Ito H,Asou I,Ohbayashi M,Ishikawa F,Kuwata H,Hara S

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2023

Intranasal Delivery of Endothelial Cell-Derived Extracellular Vesicles with Supramolecular Gel Attenuates Myocardial Ischemia-Reperfusion Injury.

International journal of nanomedicine

Wang J,Tan Y,Dai Y,Hu K,Tan X,Jiang S,Li G,Zhang X,Kang L,Wang X,Xu B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Oct 05 00:00:00 EDT 2023

The Cxcr2⁺ subset of the S100a8⁺ gastric granylocytic myeloid-derived suppressor cell population (G-MDSC) regulates gastric pathology.

Frontiers in immunology

Kao KD,Grasberger H,El-Zaatari M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Sep 29 00:00:00 EDT 2023

Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.

iScience

Gonzatti MB,Freire BM,Antunes MM,de Menezes GB,Talbot J,Peron JPS,Basso AS,Keller AC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Oct 20 00:00:00 EDT 2023

Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells.

Nature communications

Rožmanić C,Lisnić B,Pribanić Matešić M,Mihalić A,Hiršl L,Park E,Lesac Brizić A,Indenbirken D,Viduka I,Šantić M,Adler B,Yokoyama WM,Krmpotić A,Juranić Lisnić V,Jonjić S,Brizić I

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Oct 12 00:00:00 EDT 2023

LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer.

Journal for immunotherapy of cancer

Zhao T,Liu S,Hanna NH,Jalal S,Ding X,Wan J,Yan C,Du H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming.

Acta pharmaceutica Sinica. B

Wang D,Gu X,Ma X,Chen J,Zhang Q,Yu Z,Li J,Hu M,Tan X,Tang Y,Xu J,Xu M,Song Q,Song H,Jiang G,Tang Z,Gao X,Chen H

13-0112-82 was used in Flow Cytometry, Immunohistochemistry (Frozen), Sample Prep to provide direct evidences for the concept of rejuvenating microglial surveillance of multiple misfolded proteins through metabolic reprogramming, and demonstrate nanoformulated α-mangostin as a potential and universal therapy against neurodegenerative diseases.

Wed Feb 01 00:00:00 EST 2023

Topical Diacerein Decreases Skin and Splenic CD11c⁺ Dendritic Cells in Psoriasis.

International journal of molecular sciences

Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Feb 21 00:00:00 EST 2023

Intra- and interchromosomal contact mapping reveals the Igh locus has extensive conformational heterogeneity and interacts with B-lineage genes.

Cell reports

Mielczarek O,Rogers CH,Zhan Y,Matheson LS,Stubbington MJT,Schoenfelder S,Bolland DJ,Javierre BM,Wingett SW,Várnai C,Segonds-Pichon A,Conn SJ,Krueger F,Andrews S,Fraser P,Giorgetti L,Corcoran AE

13-0112-82 was used in Flow Cytometry to find that the Igh locus folds into semi-rigid subdomains and undergoes flexible looping of the VH genes to its 3' end, reconciling two views of locus organization.

Tue Sep 26 00:00:00 EDT 2023

Immunostimulatory effects of a subcritical water extract of Ganoderma.

Biomedical reports

Hattori K,Takagi H,Ogata Y,Yamada T,Horiba H,Fukata K,Sakaida T,Yashiro Y,Hasegawa S,Tanaka H

13-0112-82 was used in Flow Cytometry, Immunohistochemistry (Frozen) to demonstrate that Ganoderma (SWEG) increased hematopoietic precursor cells, immature B cells, and NK cells in the bone marrow, and T cells in the thymus.

Sun Jan 01 00:00:00 EST 2023

CD11c⁺ microglia promote white matter repair after ischemic stroke.

Cell death & disease

Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Feb 24 00:00:00 EST 2023

Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1^highCD11b⁺ cells elimination in hepatocellular carcinoma.

Acta pharmaceutica Sinica. B

Tan J,Liu T,Fan W,Wei J,Zhu B,Liu Y,Liu L,Zhang X,Chen S,Lin H,Zhang Y,Li J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2023

Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.

Materials today. Bio

Huang J,Leng X,Jiang T,Xu L,Zheng J,Fang M,Wang J,Wang Z,Zhang L

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sat Apr 01 00:00:00 EDT 2023

Non-Oncogene Addiction of KRAS-Mutant Cancers to IL-1β via Versican and Mononuclear IKKβ.

Cancers

Spella M,Ntaliarda G,Skiadas G,Lamort AS,Vreka M,Marazioti A,Lilis I,Bouloukou E,Giotopoulou GA,Pepe MAA,Weiss SAI,Petrera A,Hauck SM,Koch I,Lindner M,Hatz RA,Behr J,Arendt KAM,Giopanou I,Brunn D,Savai R,Jenne DE,de Château M,Yull FE,Blackwell TS,Stathopoulos GT

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Mar 20 00:00:00 EDT 2023

Metabolic improvement and liver regeneration by inhibiting CXXC5 function for non-alcoholic steatohepatitis treatment.

Experimental & molecular medicine

Seo SH,Kim E,Yoon M,Lee SH,Park BH,Choi KY

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2022

Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis.

Nature communications

Dai B,Xu J,Li X,Huang L,Hopkins C,Wang H,Yao H,Mi J,Zheng L,Wang J,Tong W,Chow DH,Li Y,He X,Hu P,Chen Z,Zu H,Li Y,Yao Y,Jiang Q,Qin L

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Jan 20 00:00:00 EST 2022

PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation.

Nature communications

Schmid MC,Kang SW,Chen H,Paradise M,Ghebremedhin A,Kaneda MM,Chin SM,Do A,Watterson DM,Varner JA

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2022

Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity.

PLoS neglected tropical diseases

Bhattacharya P,Ismail N,Saxena A,Gannavaram S,Dey R,Oljuskin T,Akue A,Takeda K,Yu J,Karmakar S,Dagur PK,McCoy JP,Nakhasi HL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Feb 01 00:00:00 EST 2022

Influence of the Postmortem/Storage Time of Human Corneas on the Properties of Cultured Limbal Epithelial Cells.

Cells

Le-Bel G,Desjardins P,Gross C,Cortez Ghio S,Couture C,Germain L,Guérin SL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Western Blot

Wed Aug 31 00:00:00 EDT 2022

TIM3 Expression in Anaplastic-Thyroid-Cancer-Infiltrating Macrophages: An Emerging Immunotherapeutic Target.

Biology

Palacios LM,Peyret V,Viano ME,Geysels RC,Chocobar YA,Volpini X,Pellizas CG,Nicola JP,Motran CC,Rodriguez-Galan MC,Fozzatti L

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Nov 03 00:00:00 EDT 2022

Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level.

Frontiers in pharmacology

Wu H,Xie C,Wang R,Cheng J,Xu Q,Zhao H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Feb 02 00:00:00 EST 2023

Microglial angiotensin type 2 receptors mediate sex-specific expression of inflammatory cytokines independently of circulating estrogen.

Glia

Garrido-Gil P,Pedrosa MA,Garcia-Garrote M,Pequeño-Valtierra A,Rodríguez-Castro J,García-Souto D,Rodríguez-Pérez AI,Labandeira-Garcia JL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2022

Single-cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa.

MedComm

Hu X,Wu M,Ma T,Zhang Y,Zou C,Wang R,Zhang Y,Ren Y,Li Q,Liu H,Li H,Wang T,Sun X,Yang Y,Tang M,Li X,Li J,Gao X,Li T,Zhou X

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Thu Dec 01 00:00:00 EST 2022

Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity.

Nature communications

Franklin R,Guo Y,He S,Chen M,Ji F,Zhou X,Frankhouser D,Do BT,Chiem C,Jang M,Blanco MA,Vander Heiden MG,Rockne RC,Ninova M,Sykes DB,Hochedlinger K,Lu R,Sadreyev RI,Murn J,Volk A,Cheloufi S

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Apr 29 00:00:00 EDT 2022

Biocompatible reduced graphene oxide stimulated BMSCs induce acceleration of bone remodeling and orthodontic tooth movement through promotion on osteoclastogenesis and angiogenesis.

Bioactive materials

Jiao D,Wang J,Yu W,Zhang K,Zhang N,Cao L,Jiang X,Bai Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2022

Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity.

Cancer cell

Chryplewicz A,Scotton J,Tichet M,Zomer A,Shchors K,Joyce JA,Homicsko K,Hanahan D

13-0112-82 was used in Western Blot, Flow Cytometry, Immunohistochemistry (Frozen) to assess this concept by combining vascular endothelial growth factor (VEGF) pathway inhibitors that remodel the tumor vasculature with the tricyclic antidepressant imipramine, which enhances autophagy in GBM cancer cells and unexpectedly reprograms immunosuppressive tumor-associated macrophages via inhibition of histamine receptor signaling to become immunostimulatory.

Mon Oct 10 00:00:00 EDT 2022

Impact of dietary vitamin D on immunoregulation and disease pathology in lupus-prone NZB/W F1 mice.

Frontiers in immunology

Kraemer AN,Schäfer AL,Sprenger DTL,Sehnert B,Williams JP,Luo A,Riechert L,Al-Kayyal Q,Dumortier H,Fauny JD,Winter Z,Heim K,Hofmann M,Herrmann M,Heine G,Voll RE,Chevalier N

13-0112-82 was used in Flow cytometry/Cell sorting to reveal that low VD intake promotes lupus pathology, likely via the deviation of adaptive immunity, and suggests that the correction of VD deficiency might not only exert beneficial functions by preventing osteoporosis but also serve as an important module in prophylaxis and as an add-on in the treatment of lupus and possibly other immune-mediated diseases.

Fri Dec 16 00:00:00 EST 2022

Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.

International journal of molecular sciences

Martínez-Iglesias O,Naidoo V,Carrera I,Cacabelos R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Wed Feb 23 00:00:00 EST 2022

Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.

Cell host & microbe

Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Feb 10 00:00:00 EST 2021

Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss.

The Journal of clinical investigation

Yu W,Zhong L,Yao L,Wei Y,Gui T,Li Z,Kim H,Holdreith N,Jiang X,Tong W,Dyment N,Liu XS,Yang S,Choi Y,Ahn J,Qin L

13-0112 was used in Flow cytometry/Cell sorting to identify MALPs as a critical player in controlling bone remodeling during normal bone metabolism and pathological bone loss in a RANKL-dependent fashion.

Tue Jan 19 00:00:00 EST 2021

Ucp2-dependent microglia-neuronal coupling controls ventral hippocampal circuit function and anxiety-like behavior.

Molecular psychiatry

Yasumoto Y,Stoiljkovic M,Kim JD,Sestan-Pesa M,Gao XB,Diano S,Horvath TL

13-0112-82 was used in Flow Cytometry to unmask a novel and chronotypical interaction between microglia and neurons involved in the control of brain functions.

Thu Jul 01 00:00:00 EDT 2021

Mice with a specific deficiency of Pfkfb3 in myeloid cells are protected from hypoxia-induced pulmonary hypertension.

British journal of pharmacology

Wang L,Zhang X,Cao Y,Ma Q,Mao X,Xu J,Yang Q,Zhou Y,Lucas R,Fulton DJ,Su Y,Barman SA,Hong M,Liu Z,Huo Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.

Diabetes

Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Fri Jan 01 00:00:00 EST 2021

The effects of postmortem delay on mouse and human microglia gene expression.

Glia

Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Apr 01 00:00:00 EDT 2021

Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.

Glia

Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

CD36 deficiency ameliorates drug-induced acute liver injury in mice.

Molecular medicine (Cambridge, Mass.)

Zhang C,Shi X,Su Z,Hu C,Mu X,Pan J,Li M,Teng F,Ling T,Zhao T,Xu C,Ji G,You Q

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Jun 06 00:00:00 EDT 2021

Differential roles of miR-15a/16-1 and miR-497/195 clusters in immune cell development and homeostasis.

The FEBS journal

Hutter K,Rülicke T,Drach M,Andersen L,Villunger A,Herzog S

13-0112 was used in Flow cytometry/Cell sorting to postulate that the miR-497/195 cluster is redundant to its paralog clusters or that its functional relevance is restricted to certain physiological and pathological conditions.

Mon Mar 01 00:00:00 EST 2021

Light Environment Influences Developmental Programming of the Metabolic and Visual Systems in Mice.

Investigative ophthalmology & visual science

Clarkson-Townsend DA,Bales KL,Marsit CJ,Pardue MT

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Thu Apr 01 00:00:00 EDT 2021

Effects of signaling pathway inhibitors on hematopoietic stem cells.

Molecular medicine reports

Jiang Y,Xu Z,Ma N,Yin L,Hao C,Li J

13-0112 was used in Flow cytometry/Cell sorting to determine the effect of HDACs, mTOR, GSK‚3β and p38MAPK inhibitor combinations on the efficient expansion of HSCs using flow cytometry.

Fri Jan 01 00:00:00 EST 2021

Advanced maternal age induces fetal growth restriction through decreased placental inflammatory cytokine expression and immune cell accumulation in mice.

The Journal of reproduction and development

Hirata Y,Katsukura Y,Henmi Y,Ozawa R,Shimazaki S,Kurosawa A,Torii Y,Takahashi H,Iwata H,Kuwayama T,Shirasuna K

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Aug 27 00:00:00 EDT 2021

Effect of IL-33 on pyroptosis of macrophages in mice with sepsis via NF-κB/p38 MAPK signaling pathway.

Acta cirurgica brasileira

Ke J,Cai G

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry (PFA fixed)

Fri Jun 18 00:00:00 EDT 2021

Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance.

Cellular and molecular gastroenterology and hepatology

Zhang X,Liu X,Zhou W,Du Q,Yang M,Ding Y,Hu R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunocytochemistry

Fri Mar 25 00:00:00 EDT 2022

Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.

Biology

Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry (Frozen)

Thu May 27 00:00:00 EDT 2021

Dual Activity of Ginsenoside Rb1 in Hypertrophic Cardiomyocytes and Activated Macrophages: Implications for the Therapeutic Intervention of Cardiac Hypertrophy.

Journal of inflammation research

Wang S,Cui Y,Xiong M,Li M,Wang P,Cui J,Du X,Chen Y,Zhang T

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Sat Apr 23 00:00:00 EDT 2022

Circular RNA SMEK1 promotes neuropathic pain in rats through targeting microRNA-216a-5p to mediate Thioredoxin Interacting Protein (TXNIP) expression.

Bioengineered

Xin Y,Song X,Ge Q

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Western Blot

Wed Dec 01 00:00:00 EST 2021

Mycobacterium tuberculosis Load in Host Cells and the Antibacterial Activity of Alveolar Macrophages Are Linked and Differentially Regulated in Various Lung Lesions of Patients with Pulmonary Tuberculosis.

International journal of molecular sciences

Ufimtseva EG,Eremeeva NI,Umpeleva TV,Vakhrusheva DV,Skornyakov SN

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Fri Mar 26 00:00:00 EDT 2021

Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis.

Frontiers in cardiovascular medicine

Ju B,Guo O,Benissan-Messan DZ,Shawver MH,Chen P,Geng B,Wei S,Yaron JR,Lucas AR,Zhu H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry (PFA fixed)

Fri May 20 00:00:00 EDT 2022

Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis.

Frontiers in cardiovascular medicine

Ju B,Guo O,Benissan-Messan DZ,Shawver MH,Chen P,Geng B,Wei S,Yaron JR,Lucas AR,Zhu H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry (PFA fixed)

Fri May 20 00:00:00 EDT 2022

Developmental chronodisruption alters placental signaling in mice.

PloS one

Clarkson-Townsend DA,Bales KL,Hermetz KE,Burt AA,Pardue MT,Marsit CJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunocytochemistry

Wed Nov 24 00:00:00 EST 2021

Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.

Nature communications

Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon May 17 00:00:00 EDT 2021

Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.

Nature communications

Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon May 17 00:00:00 EDT 2021

Brd4 modulates diet-induced obesity via PPARγ-dependent Gdf3 expression in adipose tissue macrophages.

JCI insight

Hu X,Dong X,Li G,Chen Y,Chen J,He X,Sun H,Kim DH,Kemper JK,Chen LF

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Apr 08 00:00:00 EDT 2021

Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.

Cells

Jhan MK,Chen CL,Shen TJ,Tseng PC,Wang YT,Satria RD,Yu CY,Lin CF

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Nov 15 00:00:00 EST 2021

Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.

Cellular and molecular gastroenterology and hepatology

Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Mar 28 00:00:00 EDT 2022

Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.

Aging

Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jul 21 00:00:00 EDT 2021

Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.

Nature communications

Fujino T,Goyama S,Sugiura Y,Inoue D,Asada S,Yamasaki S,Matsumoto A,Yamaguchi K,Isobe Y,Tsuchiya A,Shikata S,Sato N,Morinaga H,Fukuyama T,Tanaka Y,Fukushima T,Takeda R,Yamamoto K,Honda H,Nishimura EK,Furukawa Y,Shibata T,Abdel-Wahab O,Suematsu M,Kitamura T

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Mar 23 00:00:00 EDT 2021

M2 macrophage microvesicle-inspired nanovehicles improve accessibility to cancer cells and cancer stem cells in tumors.

Journal of nanobiotechnology

Wang Y,Gong X,Li J,Wang H,Xu X,Wu Y,Wang J,Wang S,Li Y,Zhang Z

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Neutralization

Sat Nov 27 00:00:00 EST 2021

Abraxane-induced bone marrow CD11b⁺ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with ⁶⁴Cu-labeled anti-CD11b and prevented by anti-CSF-1.

Theranostics

Cao Q,Huang Q,Wang YA,Li C

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jul 23 00:00:00 EDT 2021

In vitro and ex vivo evaluation of tumor-derived exosome-induced dendritic cell dysfunction in mouse.

STAR protocols

Zeng W,Yin X,Jiang Y,Jin L,Liang W

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Mar 19 00:00:00 EDT 2021

Platelet-Like Fusogenic Liposome-Mediated Targeting Delivery of miR-21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia-Reperfusion Injury.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Tan H,Song Y,Chen J,Zhang N,Wang Q,Li Q,Gao J,Yang H,Dong Z,Weng X,Wang Z,Sun D,Yakufu W,Pang Z,Huang Z,Ge J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Aug 01 00:00:00 EDT 2021

Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.

Nature communications

Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jun 08 00:00:00 EDT 2021

Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1^G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner.

Journal of neuroinflammation

MacLean M,Juranek J,Cuddapah S,López-Díez R,Ruiz HH,Hu J,Frye L,Li H,Gugger PF,Schmidt AM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry (PFA fixed)

Tue Jun 15 00:00:00 EDT 2021

Mechanical Stress Induce PG-E2 in Murine Synovial Fibroblasts Originating from the Temporomandibular Joint.

Cells

Nazet U,Feulner L,Muschter D,Neubert P,Schatz V,Grässel S,Jantsch J,Proff P,Schröder A,Kirschneck C

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2021

Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice.

Frontiers in pharmacology

Han H,Peng G,Meister M,Yao H,Yang JJ,Zou MH,Liu ZR,Ji X

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sat Apr 02 00:00:00 EDT 2022

Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.

Journal of neuroinflammation

Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Feb 18 00:00:00 EST 2021

TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.

Cell reports

Agarwal P,Li H,Choi K,Hueneman K,He J,Welner RS,Starczynowski DT,Bhatia R

13-0112-82 was used in Flow Cytometry to find that TNF-α-mediated alterations in CML BM stromal niches enhance support of LSC maintenance and growth via CXCL1-CXCR2 signaling and that CXCR2 inhibition effectively depletes CML LSCs.

Tue Jul 13 00:00:00 EDT 2021

STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.

Cellular and molecular gastroenterology and hepatology

Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Jan 24 00:00:00 EST 2022

Prevention of non-alcoholic steatohepatitis by long-term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice.

Physiological reports

Miura I,Komine S,Okada K,Wada S,Warabi E,Uchida F,Oh S,Suzuki H,Mizokami Y,Shoda J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sat May 01 00:00:00 EDT 2021

Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate.

Frontiers in cell and developmental biology

Tang W,He J,Huang T,Bai Z,Wang C,Wang H,Yang R,Ni Y,Hou J,Wang J,Zhou J,Yao Y,Gong Y,Hou S,Liu B,Lan Y

13-0112-82 was used in Flow cytometry/Cell sorting to develop an Hlf-tdTomato reporter mouse model and detected Hlf-tdTomato expression exclusively in the hematopoietic cells including part of the immunophenotypic CD45- and CD45+ pre-HSCs in the embryonic day (E) 10.5 AGM region.

Fri Oct 01 00:00:00 EDT 2021

Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).

PloS one

Lin CK,Huang TH,Yang CT,Shi CS

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Oct 12 00:00:00 EDT 2021

Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis.

Frontiers in immunology

Alam J,de Paiva CS,Pflugfelder SC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Dec 10 00:00:00 EST 2021

Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.

Cell reports

Dang MT,Gonzalez MV,Gaonkar KS,Rathi KS,Young P,Arif S,Zhai L,Alam Z,Devalaraja S,To TKJ,Folkert IW,Raman P,Rokita JL,Martinez D,Taroni JN,Shapiro JA,Greene CS,Savonen C,Mafra F,Hakonarson H,Curran T,Haldar M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Mar 30 00:00:00 EDT 2021

Systemic administration of β-glucan induces immune training in microglia.

Journal of neuroinflammation

Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Feb 22 00:00:00 EST 2021

Inflammation-induced alterations in maternal-fetal Heme Oxygenase (HO) are associated with sustained innate immune cell dysregulation in mouse offspring.

PloS one

Ozen M,Zhao H,Kalish F,Yang Y,Jantzie LL,Wong RJ,Stevenson DK

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Nov 17 00:00:00 EST 2021

A Population of M2 Macrophages Associated With Bone Formation.

Frontiers in immunology

Olmsted-Davis E,Mejia J,Salisbury E,Gugala Z,Davis AR

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Dec 13 00:00:00 EST 2021

TRPV1 sustains microglial metabolic reprogramming in Alzheimer's disease.

EMBO reports

Lu J,Zhou W,Dou F,Wang C,Yu Z

13-0112-82 was used in Flow Cytometry, Immunohistochemistry (Frozen) to indicate that TRPV1 is an important target regulating metabolic reprogramming for microglial functions in Alzheimer's disease treatment.

Fri Jun 04 00:00:00 EDT 2021

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells.

Nature

Zhang B,Ma S,Rachmin I,He M,Baral P,Choi S,Gonçalves WA,Shwartz Y,Fast EM,Su Y,Zon LI,Regev A,Buenrostro JD,Cunha TM,Chiu IM,Fisher DE,Hsu YC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Wed Jan 01 00:00:00 EST 2020

Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA.

Immunity

Soni C,Perez OA,Voss WN,Pucella JN,Serpas L,Mehl J,Ching KL,Goike J,Georgiou G,Ippolito GC,Sisirak V,Reizis B

13-0112-82 was used in Flow Cytometry to establish extrafollicular B cell differentiation into short-lived AFCs as a key mechanism of anti-DNA autoreactivity and reveal a major contribution of pDCs, endosomal Toll-like receptors (TLRs), and IFN-I to this pathway.

Tue Jun 16 00:00:00 EDT 2020

m⁶A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development.

Immunity

Gao Y,Vasic R,Song Y,Teng R,Liu C,Gbyli R,Biancon G,Nelakanti R,Lobben K,Kudo E,Liu W,Ardasheva A,Fu X,Wang X,Joshi P,Lee V,Dura B,Viero G,Iwasaki A,Fan R,Xiao A,Flavell RA,Li HB,Tebaldi T,Halene S

13-0112-82 was used in Immunocytochemistry to investigate if N6-methyladenosine modification protects against endogenous double-stranded RNAs formation and a deleterious innate immune response during mammalian hematopoietic development.

Tue Jun 16 00:00:00 EDT 2020

Heterogenous Populations of Tissue-Resident CD8⁺ T Cells Are Generated in Response to Infection and Malignancy.

Immunity

Milner JJ,Toma C,He Z,Kurd NS,Nguyen QP,McDonald B,Quezada L,Widjaja CE,Witherden DA,Crowl JT,Shaw LA,Yeo GW,Chang JT,Omilusik KD,Goldrath AW

13-0112 was used in Flow cytometry/Cell sorting to identify discrete lineages of intestinal antigen-specific CD8+ T cells, including a Blimp1hiId3lo tissue-resident effector cell population most prominent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1loId3hi tissue-resident memory population that subsequently accumulated at later infection time points.

Tue May 19 00:00:00 EDT 2020

Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.

Nano-micro letters

Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sat Nov 21 00:00:00 EST 2020

BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.

Science translational medicine

Brook B,Harbeson DJ,Shannon CP,Cai B,He D,Ben-Othman R,Francis F,Huang J,Varankovich N,Liu A,Bao W,Bjerregaard-Andersen M,Schaltz-Buchholzer F,Sanca L,Golding CN,Larsen KL,Levy O,Kampmann B,Tan R,Charles A,Wynn JL,Shann F,Aaby P,Benn CS,Tebbutt SJ,Kollmann TR,Amenyogbe N

13-0112 was used in Flow cytometry/Cell sorting to show that BCG was also protective in a mouse model of neonatal polymicrobial sepsis, where it induced granulocyte colony-stimulating factor (G-CSF) within hours of administration.

Wed May 06 00:00:00 EDT 2020

LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes.

The EMBO journal

Liu Z,Xu E,Zhao HT,Cole T,West AB

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunocytochemistry

Thu Oct 15 00:00:00 EDT 2020

IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.

Arteriosclerosis, thrombosis, and vascular biology

Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2020

Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice.

PLoS biology

Li J,Zhao Y,Choi J,Ting KK,Coleman P,Chen J,Cogger VC,Wan L,Shi Z,Moller T,Zheng X,Vadas MA,Gamble JR

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Mon Jun 01 00:00:00 EDT 2020

Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.

British journal of pharmacology

De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sat Feb 01 00:00:00 EST 2020

Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.

Mucosal immunology

Wang C,Li Q,Lv J,Sun X,Cao Y,Yu K,Miao C,Zhang ZS,Yao Z,Wang Q

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development.

The Journal of cell biology

Romero-Wolf M,Shin B,Zhou W,Koizumi M,Rothenberg EV,Hosokawa H

13-0112 was used in Flow cytometry/Cell sorting to define a distinct mechanism of Notch signal response that distinguishes the initial stages of murine T cell development.

Mon Oct 05 00:00:00 EDT 2020

Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.

Glia

Boeck M,Thien A,Wolf J,Hagemeyer N,Laich Y,Yusuf D,Backofen R,Zhang P,Boneva S,Stahl A,Hilgendorf I,Agostini H,Prinz M,Wieghofer P,Schlunck G,Schlecht A,Lange C

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2020

Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection.

Journal of leukocyte biology

Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Mouse bone marrow mesenchymal stem cells with distinct p53 statuses display differential characteristics.

Molecular medicine reports

Wang B,Wang L,Mao J,Wen H,Xu L,Ren Y,Du H,Yang H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri May 01 00:00:00 EDT 2020

Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.

Journal of cardiovascular pharmacology

Jia K,Dai Y,Liu A,Li X,Wu L,Lu L,Bao Y,Jin Q

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Thu Oct 01 00:00:00 EDT 2020

Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.

BioMed research international

Jiang JK,Hong LJ,Lu YQ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Dec 16 00:00:00 EST 2020

Exploring the Role of Osteosarcoma-Derived Extracellular Vesicles in Pre-Metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.

Cancers

Mazumdar A,Urdinez J,Boro A,Arlt MJE,Egli FE,Niederöst B,Jaeger PK,Moschini G,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Nov 20 00:00:00 EST 2020

Exploring the Role of Osteosarcoma-Derived Extracellular Vesicles in Pre-Metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.

Cancers

Mazumdar A,Urdinez J,Boro A,Arlt MJE,Egli FE,Niederöst B,Jaeger PK,Moschini G,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Nov 20 00:00:00 EST 2020

Electrotransfer of IL-15/IL-15Rα Complex for the Treatment of Established Melanoma.

Cancers

Shirley SA,Lundberg CG,Heller R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Wed Oct 21 00:00:00 EDT 2020

Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues.

Cells

Iannotta L,Biosa A,Kluss JH,Tombesi G,Kaganovich A,Cogo S,Plotegher N,Civiero L,Lobbestael E,Baekelandt V,Cookson MR,Greggio E

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry (PFA fixed)

Thu Oct 22 00:00:00 EDT 2020

The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.

Cell death & disease

Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Nov 30 00:00:00 EST 2020

The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.

Cell death & disease

Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Nov 30 00:00:00 EST 2020

Irradiation induces cancer lung metastasis through activation of the cGAS-STING-CCL5 pathway in mesenchymal stromal cells.

Cell death & disease

Zheng Z,Jia S,Shao C,Shi Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu May 07 00:00:00 EDT 2020

Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.

Cell reports

Nguyen HD,Ticer T,Bastian D,Kuril S,Li H,Du H,Yan C,Yu XZ

13-0112 was used in Flow cytometry/Cell sorting to reveal the role of LAL in T cell alloresponse and pathogenicity and validates LAL as a target for controlling GVHD and tumor relapse after allo-HCT.

Tue Oct 27 00:00:00 EDT 2020

Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure.

Frontiers in immunology

Hsu CY,Lin YC,Chang LY,Huang SK,Huang CH,Yang CK,Huang CT,Lin CY

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jun 15 00:00:00 EDT 2021

Adipocyte Fatty Acid Transfer Supports Megakaryocyte Maturation.

Cell reports

Valet C,Batut A,Vauclard A,Dortignac A,Bellio M,Payrastre B,Valet P,Severin S

13-0112-82 was used in Flow Cytometry to demonstrate the influence of adipocytes on megakaryocyte development via fatty acid transfer.

Tue Jul 07 00:00:00 EDT 2020

Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.

Journal of clinical & cellular immunology

Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sat Aug 13 00:00:00 EDT 2022

GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.

Cells

Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jan 03 00:00:00 EST 2020

Differential Activation of Macrophages Based on Their Environment in Advanced Age.

Chonnam medical journal

Lee DY,Lim JS,Cho KA

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.

Nature communications

Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2020

The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.

Nature communications

Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2020

Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization.

Frontiers in immunology

Chandran S,Schilke RM,Blackburn CMR,Yurochko A,Mirza R,Scott RS,Finck BN,Woolard MD

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Mar 29 00:00:00 EDT 2021

Ly6c^Lo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.

Scientific reports

Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Apr 28 00:00:00 EDT 2020

Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.

Cancers

Kuziel G,Thompson V,D'Amato JV,Arendt LM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jul 28 00:00:00 EDT 2020

Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis.

Frontiers in immunology

Zhou B,Yang W,Li W,He L,Lu L,Zhang L,Liu Z,Wang Y,Chao T,Huang R,Gu Y,Jia T,Liu Q,Tian S,Pierre P,Maeda T,Liang Y,Kong E

13-0112-81 was used in Flow Cytometry to analyse tissue infiltrating immune cells and cytokine production during psoriasis using mouse models.

Wed Jun 23 00:00:00 EDT 2021

The immune response after noise damage in the cochlea is characterized by a heterogeneous mix of adaptive and innate immune cells.

Scientific reports

Rai V,Wood MB,Feng H,Schabla NM,Tu S,Zuo J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Sep 16 00:00:00 EDT 2020

Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli.

ImmunoHorizons

Schilke RM,Blackburn CMR,Rao S,Krzywanski DM,Finck BN,Woolard MD

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Oct 19 00:00:00 EDT 2020

TNFAIP3 Plays a Role in Aging of the Hematopoietic System.

Frontiers in immunology

Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Apr 28 00:00:00 EDT 2021

Methylation of a CGATA element inhibits binding and regulation by GATA-1.

Nature communications

Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M

13-0112 was used in Flow cytometry/Cell sorting to show that the erythroid transcription factor GATA-1 - that typically binds T/AGATA sites - can also recognise CGATA elements, but only if the CpG dinucleotide is unmethylated.

Fri May 22 00:00:00 EDT 2020

Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.

eLife

Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

CD103⁺ cDC1 and endogenous CD8⁺ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.

Nature communications

Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System.

Biomedicines

Hong Y,Singh N,Bamopoulos S,Gjerga E,Schmalbrock LK,Balabanian K,Schick M,Keller U,Wirth M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Dec 09 00:00:00 EST 2020

Use of Busulfan to Condition Mice for Bone Marrow Transplantation.

STAR protocols

Montecino-Rodriguez E,Dorshkind K

13-0112 was used in Flow cytometry/Cell sorting to describe a protocol for the use of busulfan to condition mice for bone marrow transplantation and several of the variables to consider for effective implementation.

Fri Dec 18 00:00:00 EST 2020

Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.

Frontiers in pharmacology

Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Feb 16 00:00:00 EST 2021

L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men.

Cells

Drescher HK,Schippers A,Rosenhain S,Gremse F,Bongiovanni L,Bruin A,Eswaran S,Gallage SU,Pfister D,Szydlowska M,Heikenwalder M,Weiskirchen S,Wagner N,Trautwein C,Weiskirchen R,Kroy DC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Apr 29 00:00:00 EDT 2020

Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.

JCI insight

Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Aug 20 00:00:00 EDT 2020

Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.

Frontiers in immunology

Hering L,Katkeviciute E,Schwarzfischer M,Busenhart P,Gottier C,Mrdjen D,Komuczki J,Wawrzyniak M,Lang S,Atrott K,Becher B,Rogler G,Scharl M,Spalinger MR

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Apr 12 00:00:00 EDT 2021

Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.

Nature communications

Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Aug 27 00:00:00 EDT 2020

Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells.

JCI insight

Hadas R,Gershon E,Cohen A,Atrakchi O,Lazar S,Golani O,Dassa B,Elbaz M,Cohen G,Eilam R,Dekel N,Neeman M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2020

Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment.

eLife

Zhong L,Yao L,Tower RJ,Wei Y,Miao Z,Park J,Shrestha R,Wang L,Yu W,Holdreith N,Huang X,Zhang Y,Tong W,Gong Y,Ahn J,Susztak K,Dyment N,Li M,Long F,Chen C,Seale P,Qin L

13-0112 was used in Flow cytometry/Cell sorting to computationally define mesenchymal progenitors at different stages and delineate their bi-lineage differentiation paths in young, adult and aging mice.

Tue Apr 14 00:00:00 EDT 2020

Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b⁺Ly6G^- myeloid cells.

Aging

Fang Y,Gu Y,Li L,Zhu L,Qian J,Zhao C,Xu L,Wei W,Du Y,Yuan N,Zhang S,Yuan Y,Xu Y,Jiang C,Wang J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Nov 24 00:00:00 EST 2020

Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.

Cells

Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jul 07 00:00:00 EDT 2020

Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.

Stem cell research & therapy

Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Nov 27 00:00:00 EST 2020

CD71⁺ Erythroid Cells in Human Neonates Exhibit Immunosuppressive Properties and Compromise Immune Response Against Systemic Infection in Neonatal Mice.

Frontiers in immunology

Elahi S,Vega-López MA,Herman-Miguel V,Ramírez-Estudillo C,Mancilla-Ramírez J,Motyka B,West L,Oyegbami O

13-0112-82 was used in Flow Cytometry to study the frequency and functionality of CD71+ erythroid cells in the peripheral blood of human newborns/children from 1-day to 5-year and compared them with their counterparts in the neonatal mice.

Mon Dec 28 00:00:00 EST 2020

The cis-Regulatory Atlas of the Mouse Immune System.

Cell

Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C

13-0112-82 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.

Thu Feb 07 00:00:00 EST 2019

Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche.

Immunity

Camara A,Cordeiro OG,Alloush F,Sponsel J,Chypre M,Onder L,Asano K,Tanaka M,Yagita H,Ludewig B,Flacher V,Mueller CG

13-0112 was used in Flow cytometry/Cell sorting to demonstrate that mesenchymal stromal cells created a niche environment with LECs for specialized macrophages to take up residence, complete their differentiation program, and fulfill their immune function.

Tue Jun 18 00:00:00 EDT 2019

Microglial UCP2 Mediates Inflammation and Obesity Induced by High-Fat Feeding.

Cell metabolism

Kim JD,Yoon NA,Jin S,Diano S

13-0112 was used in Flow cytometry/Cell sorting to point to a fuel-availability-driven mitochondrial mechanism as a major player of microglia activation in the central regulation of DIO.

Tue Nov 05 00:00:00 EST 2019

Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice.

Nature immunology

Piliponsky AM,Shubin NJ,Lahiri AK,Truong P,Clauson M,Niino K,Tsuha AL,Nedospasov SA,Karasuyama H,Reber LL,Tsai M,Mukai K,Galli SJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Feb 01 00:00:00 EST 2019

Central nervous system regeneration is driven by microglia necroptosis and repopulation.

Nature neuroscience

Lloyd AF,Davies CL,Holloway RK,Labrak Y,Ireland G,Carradori D,Dillenburg A,Borger E,Soong D,Richardson JC,Kuhlmann T,Williams A,Pollard JW,des Rieux A,Priller J,Miron VE

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Jul 01 00:00:00 EDT 2019

Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.

Cell stem cell

Agarwal P,Isringhausen S,Li H,Paterson AJ,He J,Gomariz Á,Nagasawa T,Nombela-Arrieta C,Bhatia R

13-0112-82 was used in Flow Cytometry to highlight a critical role of niche-specific effects of Cxcl12 expression in maintaining quiescence of TKI-resistant LSC populations.

Thu May 02 00:00:00 EDT 2019

SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.

The Journal of clinical investigation

Abraham A,Qiu S,Chacko BK,Li H,Paterson A,He J,Agarwal P,Shah M,Welner R,Darley-Usmar VM,Bhatia R

13-0112 was used in Flow cytometry/Cell sorting to demonstrate an important role for SIRT1 in leukemia development.

Mon Jun 10 00:00:00 EDT 2019

Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages.

British journal of pharmacology

Feng L,Sun Y,Song P,Xu L,Wu X,Wu X,Shen Y,Sun Y,Kong L,Wu X,Xu Q

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2019

Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.

Journal of cellular physiology

Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed May 01 00:00:00 EDT 2019

Antiallodynic Effects of Cannabinoid Receptor 2 (CB₂R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.

Pain research & management

Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Dec 16 00:00:00 EST 2019

Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.

Anti-cancer drugs

Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.

Cell reports

Cianciaruso C,Beltraminelli T,Duval F,Nassiri S,Hamelin R,Mozes A,Gallart-Ayala H,Ceada Torres G,Torchia B,Ries CH,Ivanisevic J,De Palma M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunoprecipitation

Tue Jun 04 00:00:00 EDT 2019

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.

Cell reports

Cianciaruso C,Beltraminelli T,Duval F,Nassiri S,Hamelin R,Mozes A,Gallart-Ayala H,Ceada Torres G,Torchia B,Ries CH,Ivanisevic J,De Palma M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunoprecipitation

Tue Jun 04 00:00:00 EDT 2019

TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice.

Cell reports

Zeng J,Wang Y,Luo Z,Chang LC,Yoo JS,Yan H,Choi Y,Xie X,Deverman BE,Gradinaru V,Gupton SL,Zlokovic BV,Zhao Z,Jung JU

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Apr 09 00:00:00 EDT 2019

Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis.

Nature communications

Zhang X,Zhang H,Xu C,Li X,Li M,Wu X,Pu W,Zhou B,Wang H,Li D,Ding Q,Ying H,Wang H,Zhang H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Sep 13 00:00:00 EDT 2019

Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1.

Journal of immunology (Baltimore, Md. : 1950)

Paduch K,Debus A,Rai B,Schleicher U,Bogdan C

13-0112-82 was used in Immunohistochemistry to conclude that Arg1 expression by hematopoietic and endothelial cells is completely dispensable for clinical resolution of cutaneous leishmaniasis and for long-term persistence of L. major.

Fri Mar 01 00:00:00 EST 2019

Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine.

Scientific reports

Kimura H,Imura YK,Tomiyasu H,Mihara T,Kaji N,Ohno K,Unno T,Tanahashi Y,Jan TR,Tsubone H,Ozaki H,Hori M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Apr 10 00:00:00 EDT 2019

MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.

Journal for immunotherapy of cancer

Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Nov 28 00:00:00 EST 2019

Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.

Cellular and molecular gastroenterology and hepatology

Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jun 04 00:00:00 EDT 2019

Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.

Frontiers in immunology

Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Oct 14 00:00:00 EDT 2020

Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.

Frontiers in immunology

Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Sep 28 00:00:00 EDT 2020

Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity.

Nature metabolism

Seo JB,Riopel M,Cabrales P,Huh JY,Bandyopadhyay GK,Andreyev AY,Murphy AN,Beeman SC,Smith GI,Klein S,Lee YS,Olefsky JM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2019

Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.

Nature communications

Kurelac I,Iommarini L,Vatrinet R,Amato LB,De Luise M,Leone G,Girolimetti G,Umesh Ganesh N,Bridgeman VL,Ombrato L,Columbaro M,Ragazzi M,Gibellini L,Sollazzo M,Feichtinger RG,Vidali S,Baldassarre M,Foriel S,Vidone M,Cossarizza A,Grifoni D,Kofler B,Malanchi I,Porcelli AM,Gasparre G

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Feb 22 00:00:00 EST 2019

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence.

Journal of visualized experiments : JoVE

Kesarwani M,Kincaid Z,Azam M

13-0112 was used in Flow cytometry/Cell sorting to provide methods for target validation using in vitro and in vivo mouse models.

Mon Jan 07 00:00:00 EST 2019

Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR.

Nature communications

Zhu H,Bhatt B,Sivaprakasam S,Cai Y,Liu S,Kodeboyina SK,Patel N,Savage NM,Sharma A,Kaufman RJ,Li H,Singh N

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Mar 06 00:00:00 EST 2019

The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response.

Scientific reports

Tellez Freitas CM,Burrell HR,Valdoz JC,Hamblin GJ,Raymond CM,Cox TD,Johnson DK,Andersen JL,Weber KS,Bridgewater LC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jan 30 00:00:00 EST 2019

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.

Nature communications

Galle-Treger L,Sankaranarayanan I,Hurrell BP,Howard E,Lo R,Maazi H,Lewis G,Banie H,Epstein AL,Hu P,Rehan VK,Gilliland FD,Allayee H,Soroosh P,Sharpe AH,Akbari O

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Feb 12 00:00:00 EST 2019

Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease.

The Journal of clinical investigation

Sofi MH,Wu Y,Schutt SD,Dai M,Daenthanasanmak A,Heinrichs Voss J,Nguyen H,Bastian D,Iamsawat S,Selvam SP,Liu C,Maulik N,Ogretmen B,Jin J,Mehrotra S,Yu XZ

13-0112-82 was used in Flow Cytometry to target the ROS pathway, which can be readily translated into clinic.

Thu May 02 00:00:00 EDT 2019

Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells.

Cellular and molecular gastroenterology and hepatology

Kiyohara H,Sujino T,Teratani T,Miyamoto K,Arai MM,Nomura E,Harada Y,Aoki R,Koda Y,Mikami Y,Mizuno S,Naganuma M,Hisamatsu T,Kanai T

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Apr 29 00:00:00 EDT 2019

Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.

Nature communications

Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Nov 28 00:00:00 EST 2019

Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.

Nature medicine

Zhang B,Nguyen LXT,Li L,Zhao D,Kumar B,Wu H,Lin A,Pellicano F,Hopcroft L,Su YL,Copland M,Holyoake TL,Kuo CJ,Bhatia R,Snyder DS,Ali H,Stein AS,Brewer C,Wang H,McDonald T,Swiderski P,Troadec E,Chen CC,Dorrance A,Pullarkat V,Yuan YC,Perrotti D,Carlesso N,Forman SJ,Kortylewski M,Kuo YH,Marcucci G

13-0112 was used in Flow cytometry/Cell sorting to demonstrate how bone marrow endothelial cells supply miR-126 to leukemia stem cells in chronic myelogenous leukemia which modulates their quiescence and self-renewal.

Tue May 01 00:00:00 EDT 2018

Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells.

Nature

Kim HS,Tan Y,Ma W,Merkurjev D,Destici E,Ma Q,Suter T,Ohgi K,Friedman M,Skowronska-Krawczyk D,Rosenfeld MG

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Sun Apr 01 00:00:00 EDT 2018

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.

Nature

Morioka S,Perry JSA,Raymond MH,Medina CB,Zhu Y,Zhao L,Serbulea V,Onengut-Gumuscu S,Leitinger N,Kucenas S,Rathmell JC,Makowski L,Ravichandran KS

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Nov 01 00:00:00 EDT 2018

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Nature

Meisel M,Hinterleitner R,Pacis A,Chen L,Earley ZM,Mayassi T,Pierre JF,Ernest JD,Galipeau HJ,Thuille N,Bouziat R,Buscarlet M,Ringus DL,Wang Y,Li Y,Dinh V,Kim SM,McDonald BD,Zurenski MA,Musch MW,Furtado GC,Lira SA,Baier G,Chang EB,Eren AM,Weber CR,Busque L,Godley LA,Verdú EF,Barreiro LB,Jabri B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue May 01 00:00:00 EDT 2018

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.

Cell

Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Jan 25 00:00:00 EST 2018

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Cell

Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Jun 28 00:00:00 EDT 2018

Chanzyme TRPM7 Mediates the Ca²⁺ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.

Immunity

Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jan 16 00:00:00 EST 2018

E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.

Immunity

Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Feb 20 00:00:00 EST 2018

Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.

Immunity

Hirota K,Hashimoto M,Ito Y,Matsuura M,Ito H,Tanaka M,Watanabe H,Kondoh G,Tanaka A,Yasuda K,Kopf M,Potocnik AJ,Stockinger B,Sakaguchi N,Sakaguchi S

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jun 19 00:00:00 EDT 2018

Insulin resistance causes inflammation in adipose tissue.

The Journal of clinical investigation

Shimobayashi M,Albert V,Woelnerhanssen B,Frei IC,Weissenberger D,Meyer-Gerspach AC,Clement N,Moes S,Colombi M,Meier JA,Swierczynska MM,Jenö P,Beglinger C,Peterli R,Hall MN

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Apr 02 00:00:00 EDT 2018

Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease.

The Journal of clinical investigation

Tsantikos E,Lau M,Castelino CM,Maxwell MJ,Passey SL,Hansen MJ,McGregor NE,Sims NA,Steinfort DP,Irving LB,Anderson GP,Hibbs ML

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

IL1RAP potentiates multiple oncogenic signaling pathways in AML.

The Journal of experimental medicine

Mitchell K,Barreyro L,Todorova TI,Taylor SJ,Antony-Debré I,Narayanagari SR,Carvajal LA,Leite J,Piperdi Z,Pendurti G,Mantzaris I,Paietta E,Verma A,Gritsman K,Steidl U

13-0112 was used in Flow cytometry/Cell sorting to show that targeting of interleukin-1 receptor accessory protein via RNA interference, genetic deletion, or antibodies inhibits acute myeloid leukaemia pathogenesis in vitro and in vivo.

Mon Jun 04 00:00:00 EDT 2018

Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.

Journal of the American Society of Nephrology : JASN

Micanovic R,Khan S,Janosevic D,Lee ME,Hato T,Srour EF,Winfree S,Ghosh J,Tong Y,Rice SE,Dagher PC,Wu XR,El-Achkar TM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Mar 01 00:00:00 EST 2018

11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.

Journal of autoimmunity

Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Aug 01 00:00:00 EDT 2018

Sialic Acid Blockade Suppresses Tumor Growth by Enhancing T-cell-Mediated Tumor Immunity.

Cancer research

Büll C,Boltje TJ,Balneger N,Weischer SM,Wassink M,van Gemst JJ,Bloemendal VR,Boon L,van der Vlag J,Heise T,den Brok MH,Adema GJ

13-0112 was used in Immunohistochemistry to show that sialic acid sugars function as important modulators of the immunosuppressive tumor microenvironment that limit potent antitumor immunity.

Sun Jul 01 00:00:00 EDT 2018

MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.

Proceedings of the National Academy of Sciences of the United States of America

Suarez-Lopez L,Sriram G,Kong YW,Morandell S,Merrick KA,Hernandez Y,Haigis KM,Yaffe MB

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Tue May 01 00:00:00 EDT 2018

MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.

Proceedings of the National Academy of Sciences of the United States of America

Suarez-Lopez L,Sriram G,Kong YW,Morandell S,Merrick KA,Hernandez Y,Haigis KM,Yaffe MB

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Tue May 01 00:00:00 EDT 2018

The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease.

Aging and disease

Zhao YF,Zhang JF,Lou ZY,Zu HB,Wang ZG,Zeng WC,Xiao BG

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Mon Oct 01 00:00:00 EDT 2018

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.

Glia

Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

Protection by and maintenance of CD4 effector memory and effector T cell subsets in persistent malaria infection.

PLoS pathogens

Opata MM,Ibitokou SA,Carpio VH,Marshall KM,Dillon BE,Carl JC,Wilson KD,Arcari CM,Stephens R

13-0112 was used in Flow cytometry/Cell sorting to elucidate four mechanisms of Tem maintenance, and identify two long-lived T cell subsets (TemLate, TeffEarly) that may represent correlates of protection or a target for longerlived vaccine-induced protection against malaria blood-stages.

Sun Apr 01 00:00:00 EDT 2018

Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes.

Journal of cellular physiology

Liron T,Raphael B,Hiram-Bab S,Bab IA,Gabet Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Apr 01 00:00:00 EDT 2018

Frontline Science: Macrophage-derived exosomes promote neutrophil necroptosis following hemorrhagic shock.

Journal of leukocyte biology

Jiao Y,Li Z,Loughran PA,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Shi X,Fan J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

The Outcome of the Cryptococcus neoformans-Macrophage Interaction Depends on Phagolysosomal Membrane Integrity.

Journal of immunology (Baltimore, Md. : 1950)

De Leon-Rodriguez CM,Rossi DCP,Fu MS,Dragotakes Q,Coelho C,Guerrero Ros I,Caballero B,Nolan SJ,Casadevall A

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Jul 15 00:00:00 EDT 2018

Primary cilia disruption differentially affects the infiltrating and resident macrophage compartment in the liver.

American journal of physiology. Gastrointestinal and liver physiology

Zimmerman KA,Song CJ,Gonzalez-Mize N,Li Z,Yoder BK

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice.

Molecular medicine reports

Wang X,Zhang Y,Wang Z,Liu X,Zhu G,Han G,Chen G,Hou C,Wang T,Shen B,Li Y,Xiao H,Ma N,Wang R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

A novel method to isolate mesenchymal stem cells from mouse umbilical cord.

Molecular medicine reports

Zhang B,Zhang J,Shi H,Mao F,Wang J,Yan Y,Zhang X,Qian H,Xu W

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.

Experimental hematology

Serrano-Lopez J,Nattamai K,Pease NA,Shephard MS,Wellendorf AM,Sertorio M,Smith EA,Geiger H,Wells SI,Cancelas JA,Privette Vinnedge LM

13-0112 was used in Flow cytometry/Cell sorting to investigate the role of DEK in normal hematopoiesis and response to DNA damaging agents in vivo.

Thu Mar 01 00:00:00 EST 2018

Morphine-potentiated cognitive deficits correlate to suppressed hippocampal iNOS RNA expression and an absent type 1 interferon response in LP-BM5 murine AIDS.

Journal of neuroimmunology

McLane VD,Kumar S,Leeming R,Rau S,Willis CL,Cao L

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Fri Jun 15 00:00:00 EDT 2018

Simultaneous isolation of mesenchymal stem cells and endothelial progenitor cells derived from murine bone marrow.

Experimental and therapeutic medicine

Wang X,Zhao Z,Zhang H,Hou J,Feng W,Zhang M,Guo J,Xia J,Ge Q,Chen X,Wu X

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

Contribution of CD137L to Sensory Hypersensitivity in a Murine Model of Neuropathic Pain.

eNeuro

Wakley AA,Leeming R,Malon J,Arabatzis TJ,Yuen Koh W,Cao L

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Fri Apr 19 00:00:00 EDT 2019

Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model.

JCI insight

Flemming S,Luissint AC,Nusrat A,Parkos CA

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Thu Oct 18 00:00:00 EDT 2018

Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.

Frontiers in physiology

Lim D,Kim W,Lee C,Bae H,Kim J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Sep 30 00:00:00 EDT 2020

Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.

Frontiers in physiology

Lim D,Kim W,Lee C,Bae H,Kim J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Sep 30 00:00:00 EDT 2020

Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria.

Journal of neuroinflammation

Wilson KD,Ochoa LF,Solomon OD,Pal R,Cardona SM,Carpio VH,Keiser PH,Cardona AE,Vargas G,Stephens R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Mon Jun 04 00:00:00 EDT 2018

Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria.

Journal of neuroinflammation

Wilson KD,Ochoa LF,Solomon OD,Pal R,Cardona SM,Carpio VH,Keiser PH,Cardona AE,Vargas G,Stephens R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Mon Jun 04 00:00:00 EDT 2018

MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.

Nature communications

Clemente C,Rius C,Alonso-Herranz L,Martín-Alonso M,Pollán Á,Camafeita E,Martínez F,Mota RA,Núñez V,Rodríguez C,Seiki M,Martínez-González J,Andrés V,Ricote M,Arroyo AG

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Neutralization

Fri Mar 02 00:00:00 EST 2018

Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.

Cell stem cell

Tadokoro Y,Hoshii T,Yamazaki S,Eto K,Ema H,Kobayashi M,Ueno M,Ohta K,Arai Y,Hara E,Harada K,Oshima M,Oshima H,Arai F,Yoshimura A,Nakauchi H,Hirao A

13-0112-82 was used in Flow Cytometry to demonstrate the involvement of diet-induced stress on hematopoietic stem cell self-renewal.

Thu May 03 00:00:00 EDT 2018

iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.

JCI insight

Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Feb 08 00:00:00 EST 2018

Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice.

Nature communications

Grinenko T,Eugster A,Thielecke L,Ramasz B,Krüger A,Dietz S,Glauche I,Gerbaulet A,von Bonin M,Basak O,Clevers H,Chavakis T,Wielockx B

13-0112-82 was used in Flow Cytometry to study the mechanisms that control fate decision in adult haematopoietic stem cells.s.

Tue May 15 00:00:00 EDT 2018

A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.

Nature communications

Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Apr 18 00:00:00 EDT 2018

Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.

Frontiers in immunology

Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Sep 25 00:00:00 EDT 2019

A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.

eLife

Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY

13-0112 was used in Flow cytometry/Cell sorting to study the activation of Bcl11b, which controls T-cell fate commitment.

Tue Nov 20 00:00:00 EST 2018

Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.

Journal of neuroinflammation

Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Sep 21 00:00:00 EDT 2018

Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.

Oncotarget

Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Apr 24 00:00:00 EDT 2018

BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells.

Oncotarget

Romano E,Rufo N,Korf H,Mathieu C,Garg AD,Agostinis P

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Apr 03 00:00:00 EDT 2018

An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages.

Scientific reports

Beneke V,Küster F,Neehus AL,Hesse C,Lopez-Rodriguez E,Haake K,Rafiei Hashtchin A,Schott JW,Walter D,Braun A,Wolkers WF,Ackermann M,Lachmann N

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Nov 02 00:00:00 EDT 2018

Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge.

Nature communications

Yi S,Zhai J,Niu R,Zhu G,Wang M,Liu J,Huang H,Wang Y,Jing X,Kang L,Song W,Shi Y,Tang H

13-0112 was used in Flow cytometry/Cell sorting to suggest that different lung antigen-presenting cells modulate lung cDC1-mediated eosinophil recruitment dynamically.

Mon Sep 24 00:00:00 EDT 2018

The orphan nuclear receptor EAR-2 (NR2F6) inhibits hematopoietic cell differentiation and induces myeloid dysplasia in vivo.

Biomarker research

Ichim CV,Dervovic DD,Chan LSA,Robertson CJ,Chesney A,Reis MD,Wells RA

Wed Mar 30 00:00:00 EDT 2022

Flt3 ligand expands bona fide innate lymphoid cell precursors in vivo.

Scientific reports

Parigi SM,Czarnewski P,Das S,Steeg C,Brockmann L,Fernandez-Gaitero S,Yman V,Forkel M,Höög C,Mjösberg J,Westerberg L,Färnert A,Huber S,Jacobs T,Villablanca EJ

Tue Jan 09 00:00:00 EST 2018

RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.

The Journal of biological chemistry

Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jun 15 00:00:00 EDT 2018

Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.

Nature communications

Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K

13-0112 was used in Flow cytometry/Cell sorting to study paediatric acute myeloid leukaemia biology, and provide murine models that offer the potential for developing paediatric specific therapeutic strategies.

Tue Dec 11 00:00:00 EST 2018

JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression.

Nature medicine

Zhao X,Guo Y,Jiang C,Chang Q,Zhang S,Luo T,Zhang B,Jia X,Hung MC,Dong C,Lin X

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.

Nature

Tammela T,Sanchez-Rivera FJ,Cetinbas NM,Wu K,Joshi NS,Helenius K,Park Y,Azimi R,Kerper NR,Wesselhoeft RA,Gu X,Schmidt L,Cornwall-Brady M,Yilmaz ÖH,Xue W,Katajisto P,Bhutkar A,Jacks T

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Thu May 18 00:00:00 EDT 2017

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.

Nature

Tammela T,Sanchez-Rivera FJ,Cetinbas NM,Wu K,Joshi NS,Helenius K,Park Y,Azimi R,Kerper NR,Wesselhoeft RA,Gu X,Schmidt L,Cornwall-Brady M,Yilmaz ÖH,Xue W,Katajisto P,Bhutkar A,Jacks T

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Thu May 18 00:00:00 EDT 2017

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

Nature

Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Apr 06 00:00:00 EDT 2017

Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy.

Cell

Cabezas-Wallscheid N,Buettner F,Sommerkamp P,Klimmeck D,Ladel L,Thalheimer FB,Pastor-Flores D,Roma LP,Renders S,Zeisberger P,Przybylla A,Schönberger K,Scognamiglio R,Altamura S,Florian CM,Fawaz M,Vonficht D,Tesio M,Collier P,Pavlinic D,Geiger H,Schroeder T,Benes V,Dick TP,Rieger MA,Stegle O,Trumpp A

Thu May 18 00:00:00 EDT 2017

Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo.

Cancer cell

Leanza L,Romio M,Becker KA,Azzolini M,Trentin L,Managò A,Venturini E,Zaccagnino A,Mattarei A,Carraretto L,Urbani A,Kadow S,Biasutto L,Martini V,Severin F,Peruzzo R,Trimarco V,Egberts JH,Hauser C,Visentin A,Semenzato G,Kalthoff H,Zoratti M,Gulbins E,Paradisi C,Szabo I

13-0112 was used in Flow cytometry/Cell sorting to demonstrate that specific pharmacological targeting of a mitochondrial potassium channel can lead to reactive oxygen species-mediated selective apoptosis of cancer cells in vivo, without significant side effects.

Mon Apr 10 00:00:00 EDT 2017

Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.

Nature immunology

Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2017

AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis.

Circulation research

Abdel Malik R,Zippel N,Frömel T,Heidler J,Zukunft S,Walzog B,Ansari N,Pampaloni F,Wingert S,Rieger MA,Wittig I,Fisslthaler B,Fleming I

13-0112 was used in Flow cytometry/Cell sorting to elucidate the role of the AMPKa2 catalytic subunit in vascular repair following ischemia.

Fri Jan 06 00:00:00 EST 2017

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.

The Journal of clinical investigation

Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.

The EMBO journal

Kawasaki T,Ito K,Miyata H,Akira S,Kawai T

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jun 14 00:00:00 EDT 2017

Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis.

Autophagy

Qiang L,Sample A,Shea CR,Soltani K,Macleod KF,He YY

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Fri Jul 05 00:00:00 EDT 2019

Pre/pro-B cells generate macrophage populations during homeostasis and inflammation.

Proceedings of the National Academy of Sciences of the United States of America

Audzevich T,Bashford-Rogers R,Mabbott NA,Frampton D,Freeman TC,Potocnik A,Kellam P,Gilroy DW

13-0112 was used in Flow cytometry/Cell sorting to study the developmental plasticity of immature B cells and their role as the source of tissue resident macrophages.

Tue May 16 00:00:00 EDT 2017

Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.

Proceedings of the National Academy of Sciences of the United States of America

Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue May 16 00:00:00 EDT 2017

CCR2^- and CCR2⁺ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.

Mucosal immunology

Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Sep 01 00:00:00 EDT 2017

Depletion of microglia exacerbates postischemic inflammation and brain injury.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Wang W,Wang H,Zhou X,Li X,Sun W,Dellinger M,Boyce BF,Xing L

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

Lung Epithelial Cell-Derived Microvesicles Regulate Macrophage Migration via MicroRNA-17/221-Induced Integrin β₁ Recycling.

Journal of immunology (Baltimore, Md. : 1950)

Lee H,Zhang D,Wu J,Otterbein LE,Jin Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Aug 15 00:00:00 EDT 2017

Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.

International journal of molecular medicine

Zhang B,Wang B,Cao S,Wang Y,Wu D

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.

RNA biology

Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu May 04 00:00:00 EDT 2017

β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.

Journal of cellular biochemistry

Vafaei R,Nassiri SM,Siavashi V

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Dec 01 00:00:00 EST 2017

Growth inhibition of formed corneal neovascularization following Fosaprepitant treatment.

Acta ophthalmologica

Bignami F,Lorusso A,Rama P,Ferrari G

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Nov 01 00:00:00 EDT 2017

Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2.

Alcoholism, clinical and experimental research

Lawrimore CJ,Crews FT

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

Chronic Plasmodium chabaudi Infection Generates CD4 Memory T Cells with Increased T Cell Receptor Sensitivity but Poor Secondary Expansion and Increased Apoptosis.

Infection and immunity

Opata MM,Stephens R

13-0112 was used in Flow cytometry/Cell sorting to determine the functional capacity of CD4 T cells generated by chronic infection by reexposure to parasite.

Wed Mar 01 00:00:00 EST 2017

Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling.

Oncotarget

Li CG,Yan L,Jing YY,Xu LH,Liang YD,Wei HX,Hu B,Pan H,Zha QB,Ouyang DY,He XH

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Tue Jan 03 00:00:00 EST 2017

HDAC3 inhibition ameliorates spinal cord injury by immunomodulation.

Scientific reports

Kuboyama T,Wahane S,Huang Y,Zhou X,Wong JK,Koemeter-Cox A,Martini M,Friedel RH,Zou H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Thu Aug 17 00:00:00 EDT 2017

Interleukin-1β signaling in fenestrated capillaries is sufficient to trigger sickness responses in mice.

Journal of neuroinflammation

Knoll JG,Krasnow SM,Marks DL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Thu Nov 09 00:00:00 EST 2017

Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer.

Oncotarget

Zamanian-Daryoush M,Lindner DJ,DiDonato JA,Wagner M,Buffa J,Rayman P,Parks JS,Westerterp M,Tall AR,Hazen SL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Sep 22 00:00:00 EDT 2017

Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment.

Scientific reports

Yeku OO,Purdon TJ,Koneru M,Spriggs D,Brentjens RJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Sep 05 00:00:00 EDT 2017

MiR-125a Is a critical modulator for neutrophil development.

PLoS genetics

Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2017

Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.

Stem cell research & therapy

Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Nov 10 00:00:00 EST 2017

Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.

Oncotarget

Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Dec 12 00:00:00 EST 2017

Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.

Cell death & disease

Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity.

NPJ vaccines

Stephen J,Scales HE,Benson RA,Erben D,Garside P,Brewer JM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Apr 08 00:00:00 EDT 2022

In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.

Particle and fibre toxicology

Jatana S,Palmer BC,Phelan SJ,Gelein R,DeLouise LA

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Apr 14 00:00:00 EDT 2017

Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.

JCI insight

Kienhöfer D,Hahn J,Stoof J,Csepregi JZ,Reinwald C,Urbonaviciute V,Johnsson C,Maueröder C,Podolska MJ,Biermann MH,Leppkes M,Harrer T,Hultqvist M,Olofsson P,Munoz LE,Mocsai A,Herrmann M,Schett G,Holmdahl R,Hoffmann MH

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu May 18 00:00:00 EDT 2017

Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation.

Nature communications

Xu Y,Wang Y,Yan S,Yang Q,Zhou Y,Zeng X,Liu Z,An X,Toque HA,Dong Z,Jiang X,Fulton DJ,Weintraub NL,Li Q,Bagi Z,Hong M,Boison D,Wu C,Huo Y

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Oct 16 00:00:00 EDT 2017

CIITA-driven MHC class II expressing tumor cells can efficiently prime naive CD4⁺ TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells.

Oncoimmunology

Bou Nasser Eddine F,Forlani G,Lombardo L,Tedeschi A,Tosi G,Accolla RS

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2021

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

JCI insight

Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Sep 21 00:00:00 EDT 2017

Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.

Cell

Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Oct 06 00:00:00 EDT 2016

Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions.

Cell

Bernitz JM,Kim HS,MacArthur B,Sieburg H,Moore K

13-0112 was used in Flow cytometry/Cell sorting to suggest that HSCs accumulate discrete memory stages over their divisional history and identify cellular memory in HSC aging.

Thu Nov 17 00:00:00 EST 2016

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.

Cell

Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Aug 25 00:00:00 EDT 2016

Acidic chitinase primes the protective immune response to gastrointestinal nematodes.

Nature immunology

Vannella KM,Ramalingam TR,Hart KM,de Queiroz Prado R,Sciurba J,Barron L,Borthwick LA,Smith AD,Mentink-Kane M,White S,Thompson RW,Cheever AW,Bock K,Moore I,Fitz LJ,Urban JF,Wynn TA

13-0112 was used in Flow cytometry/Cell sorting to use AMCase-deficient mice as a means to dissect the role of the enzyme in several models of helminth infection and type 2 cytokine-driven airway inflammation.

Sun May 01 00:00:00 EDT 2016

Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.

Nature immunology

Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Oligodendrocyte death results in immune-mediated CNS demyelination.

Nature neuroscience

Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2016

Oligodendrocyte death results in immune-mediated CNS demyelination.

Nature neuroscience

Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2016

The breast tumor microenvironment alters the phenotype and function of natural killer cells.

Cellular & molecular immunology

Krneta T,Gillgrass A,Chew M,Ashkar AA

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

The composition of the microbiota modulates allograft rejection.

The Journal of clinical investigation

Lei YM,Chen L,Wang Y,Stefka AT,Molinero LL,Theriault B,Aquino-Michaels K,Sivan AS,Nagler CR,Gajewski TF,Chong AS,Bartman C,Alegre ML

13-0112 was used in Flow cytometry/Cell sorting to test the influence of host and donor microbiota on skin transplant rejection.

Fri Jul 01 00:00:00 EDT 2016

Alternatively activated macrophages determine repair of the infarcted adult murine heart.

The Journal of clinical investigation

Shiraishi M,Shintani Y,Shintani Y,Ishida H,Saba R,Yamaguchi A,Adachi H,Yashiro K,Suzuki K

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jun 01 00:00:00 EDT 2016

IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization.

The Journal of experimental medicine

Yoon J,Leyva-Castillo JM,Wang G,Galand C,Oyoshi MK,Kumar L,Hoff S,He R,Chervonsky A,Oppenheim JJ,Kuchroo VK,van den Brink MR,Malefyt Rde W,Tessier PA,Fuhlbrigge R,Rosenstiel P,Terhorst C,Murphy G,Geha RS

13-0112 was used in Flow cytometry/Cell sorting to elucidate the mechanisms behind DC-derived IL-23 in a model of skin inflammation.

Mon Sep 19 00:00:00 EDT 2016

CD8⁺ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure.

Journal of autoimmunity

Gravano DM,Al-Kuhlani M,Davini D,Sanders PD,Manilay JO,Hoyer KK

13-0112 was used in Flow cytometry/Cell sorting to investigate whether CD8+ T cells play a non-redundant role in driving bone marrow failure.

Thu Dec 01 00:00:00 EST 2016

ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages.

Frontiers in immunology

Zha QB,Wei HX,Li CG,Liang YD,Xu LH,Bai WJ,Pan H,He XH,Ouyang DY

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Nov 20 00:00:00 EST 2019

Loss of Keratin 17 induces tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo.

Oncogene

Hobbs RP,Batazzi AS,Han MC,Coulombe PA

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Thu Oct 27 00:00:00 EDT 2016

Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.

Stem cells translational medicine

Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.

Immunology

Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sat Oct 01 00:00:00 EDT 2016

Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor.

Journal of cellular physiology

Li Y,Adomat H,Guns ET,Hojabrpour P,Duronio V,Curran TA,Jalili RB,Jia W,Delwar Z,Zhang Y,Elizei SS,Ghahary A

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunocytochemistry

Wed Jun 01 00:00:00 EDT 2016

Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype.

Journal of ginseng research

Ren K,Jin C,Ma P,Ren Q,Jia Z,Zhu D

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Fri Apr 01 00:00:00 EDT 2016

Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype.

Journal of ginseng research

Ren K,Jin C,Ma P,Ren Q,Jia Z,Zhu D

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Fri Apr 01 00:00:00 EDT 2016

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.

Disease models & mechanisms

Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.

Disease models & mechanisms

Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis.

Laboratory investigation; a journal of technical methods and pathology

Connor AL,Kelley PM,Tempero RM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Tue Mar 01 00:00:00 EST 2016

Differences between Mycobacterium-Host Cell Relationships in Latent Tuberculous Infection of Mice Ex Vivo and Mycobacterial Infection of Mouse Cells In Vitro.

Journal of immunology research

Ufimtseva E

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Tue Nov 08 00:00:00 EST 2016

ECM-Dependence of Endothelial Progenitor Cell Features.

Journal of cellular biochemistry

Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2016

Rho kinase II interference by small hairpin RNA ameliorates 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine‑induced parkinsonism in mice.

Molecular medicine reports

Zhang Q,Zhao YF,Xi JY,Yu WB,Xiao BG

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Thu Dec 01 00:00:00 EST 2016

Sertoli cell condition medium can induce germ like cells from bone marrow derived mesenchymal stem cells.

Iranian journal of basic medical sciences

Monfared MH,Minaee B,Rastegar T,Khrazinejad E,Barbarestani M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Nov 01 00:00:00 EDT 2016

Macrophages form functional vascular mimicry channels in vivo.

Scientific reports

Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Fri Nov 11 00:00:00 EST 2016

Macrophages form functional vascular mimicry channels in vivo.

Scientific reports

Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Fri Nov 11 00:00:00 EST 2016

Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.

Stem cell reports

Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Aug 09 00:00:00 EDT 2016

Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.

Cell death & disease

Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Jul 28 00:00:00 EDT 2016

Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells.

eLife

Allison KA,Sajti E,Collier JG,Gosselin D,Troutman TD,Stone EL,Hedrick SM,Glass CK

13-0112 was used in Magnetic cell separation to investigate relationship between the strength of antigenic stimulation and the response of mouse CD4+ T cells.

Mon Jul 04 00:00:00 EDT 2016

Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.

Oncoimmunology

Vila-Leahey A,Oldford SA,Marignani PA,Wang J,Haidl ID,Marshall JS

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jul 01 00:00:00 EDT 2016

p38 MAPK Inhibitor Insufficiently Attenuates HSC Senescence Administered Long-Term after 6 Gy Total Body Irradiation in Mice.

International journal of molecular sciences

Lu L,Wang YY,Zhang JL,Li DG,Meng AM

13-0112 was used in Flow cytometry/Cell sorting to investigate the effects of SB203580 on long-term TBI-induced myelosuppression.

Wed Jun 08 00:00:00 EDT 2016

Interleukin 6 regulates psoriasiform inflammation-associated thrombosis.

JCI insight

Wang Y,Golden JB,Fritz Y,Zhang X,Diaconu D,Camhi MI,Gao H,Dawes SM,Xing X,Ganesh SK,Gudjonsson JE,Simon DI,McCormick TS,Ward NL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Dec 08 00:00:00 EST 2016

Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.

Aging

McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jul 01 00:00:00 EDT 2016

NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.

Nature communications

Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Sep 07 00:00:00 EDT 2016

The impact of ranitidine on monocyte responses in the context of solid tumors.

Oncotarget

Vila-Leahey A,Rogers D,Marshall JS

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Mar 08 00:00:00 EST 2016

Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice.

Scientific reports

Watari K,Shibata T,Nabeshima H,Shinoda A,Fukunaga Y,Kawahara A,Karasuyama K,Fukushi J,Iwamoto Y,Kuwano M,Ono M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Jan 18 00:00:00 EST 2016

Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.

Oncoimmunology

Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2016

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.

Scientific reports

Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jun 15 00:00:00 EDT 2016

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.

Nature medicine

Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2015

Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool.

Nature

Mesa KR,Rompolas P,Zito G,Myung P,Sun TY,Brown S,Gonzalez DG,Blagoev KB,Haberman AM,Greco V

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Thu Jun 04 00:00:00 EDT 2015

Host microbiota constantly control maturation and function of microglia in the CNS.

Nature neuroscience

Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

Blood

Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2015

Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.

Circulation research

Ye YX,Calcagno C,Binderup T,Courties G,Keliher EJ,Wojtkiewicz GR,Iwamoto Y,Tang J,Pérez-Medina C,Mani V,Ishino S,Johnbeck CB,Knigge U,Fayad ZA,Libby P,Weissleder R,Tawakol A,Dubey S,Belanger AP,Di Carli MF,Swirski FK,Kjaer A,Mulder WJ,Nahrendorf M

13-0112 was used in Flow cytometry/Cell sorting to perform (18)F-FLT positron emission tomography-computed tomography was performed in mice, rabbits, and humans with atherosclerosis.

Fri Oct 23 00:00:00 EDT 2015

Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.

The Journal of clinical investigation

Fond AM,Lee CS,Schulman IG,Kiss RS,Ravichandran KS

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.

The Journal of clinical investigation

Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.

The Journal of clinical investigation

Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Dec 01 00:00:00 EST 2015

STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.

The Journal of clinical investigation

Li W,Xiao J,Zhou X,Xu M,Hu C,Xu X,Lu Y,Liu C,Xue S,Nie L,Zhang H,Li Z,Zhang Y,Ji F,Hui L,Tao W,Wei B,Wang H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

Distinct germinal center selection at local sites shapes memory B cell response to viral escape.

The Journal of experimental medicine

Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y

13-0112 was used in Flow cytometry/Cell sorting to investigate the cellular events dictating the cross-reactive memory B cell responses, showing that distinct germinal center selection at local sites shapes response to viral escape.

Mon Sep 21 00:00:00 EDT 2015

Distinct germinal center selection at local sites shapes memory B cell response to viral escape.

The Journal of experimental medicine

Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y

Mon Sep 21 00:00:00 EDT 2015

BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.

The Journal of experimental medicine

Jacque E,Schweighoffer E,Tybulewicz VL,Ley SC

13-0112 was used in Flow cytometry/Cell sorting to reveal a potentially critical role for the MEK5-ERK5 MAP kinase signalling pathway in BAFF-induced mature B cell survival and homeostatic maintenance of B2 cell numbers.

Mon Jun 01 00:00:00 EDT 2015

Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.

Brain : a journal of neurology

Natrajan MS,de la Fuente AG,Crawford AH,Linehan E,Nuñez V,Johnson KR,Wu T,Fitzgerald DC,Ricote M,Bielekova B,Franklin RJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Dec 01 00:00:00 EST 2015

Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.

Journal of the American Society of Nephrology : JASN

Micanovic R,Chitteti BR,Dagher PC,Srour EF,Khan S,Hato T,Lyle A,Tong Y,Wu XR,El-Achkar TM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Cis-regulatory mechanisms governing stem and progenitor cell transitions.

Science advances

Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.

Cancer research

Kratochvill F,Gratz N,Qualls JE,Van De Velde LA,Chi H,Kovarik P,Murray PJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Western Blot

Sat Aug 01 00:00:00 EDT 2015

COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset.

Proceedings of the National Academy of Sciences of the United States of America

Larsson K,Kock A,Idborg H,Arsenian Henriksson M,Martinsson T,Johnsen JI,Korotkova M,Kogner P,Jakobsson PJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Tue Jun 30 00:00:00 EDT 2015

Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases.

Breast cancer research : BCR

Tabariès S,Ouellet V,Hsu BE,Annis MG,Rose AA,Meunier L,Carmona E,Tam CE,Mes-Masson AM,Siegel PM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Fri Mar 27 00:00:00 EDT 2015

Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency.

Glia

Verheijden S,Beckers L,Casazza A,Butovsky O,Mazzone M,Baes M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Aging-like changes in the transcriptome of irradiated microglia.

Glia

Li MD,Burns TC,Kumar S,Morgan AA,Sloan SA,Palmer TD

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri May 01 00:00:00 EDT 2015

Premature thymic involution is independent of structural plasticity of the thymic stroma.

European journal of immunology

Franckaert D,Schlenner SM,Heirman N,Gill J,Skogberg G,Ekwall O,Put K,Linterman MA,Dooley J,Liston A

13-0112 was used in Flow cytometry/Cell sorting to investigate thymic involution in FVB/N mice, showing that disruption of the epithelial-endothelial relationship and a progressive loss of pro-T cells precedes involution, and loss of pro-T cells is sufficient to drive premature involution, suggesting that pro-T cells are the main driver of involution.

Fri May 01 00:00:00 EDT 2015

Frizzled-6 Regulates Hematopoietic Stem/Progenitor Cell Survival and Self-Renewal.

Journal of immunology (Baltimore, Md. : 1950)

Abidin BM,Owusu Kwarteng E,Heinonen KM

13-0112 was used in Flow cytometry/Cell sorting to reveal that Fzd6 has an essential role in HSPC maintenance and survival.

Tue Sep 01 00:00:00 EDT 2015

DGCR14 induces Il17a gene expression through the RORγ/BAZ1B/RSKS2 complex.

Molecular and cellular biology

Takada I

13-0112 was used in Magnetic cell separation to show the roles of DGCR14, RSK2, and BAZ1B in the transcriptional regulation of Il17a mRNA during TH17 cell differentiation.

Thu Jan 01 00:00:00 EST 2015

Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.

Tissue engineering. Part A

Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Apr 01 00:00:00 EDT 2015

Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.

Molecular medicine reports

Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.

BioMed research international

Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2016

Mesenchymal stem cells can prevent alterations in behavior and neurogenesis induced by Aß25-35 administration.

Journal of molecular neuroscience : MN

Hamisha KN,Tfilin M,Yanai J,Turgeman G

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Wed Apr 01 00:00:00 EDT 2015

Pathogenic Yersinia Promotes Its Survival by Creating an Acidic Fluid-Accessible Compartment on the Macrophage Surface.

PloS one

Bahnan W,Boettner DR,Westermark L,Fällman M,Schesser K

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Tue May 10 00:00:00 EDT 2016

Pathogenic Yersinia Promotes Its Survival by Creating an Acidic Fluid-Accessible Compartment on the Macrophage Surface.

PloS one

Bahnan W,Boettner DR,Westermark L,Fällman M,Schesser K

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Tue May 10 00:00:00 EDT 2016

Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.

The Journal of biological chemistry

Pamir N,Liu NC,Irwin A,Becker L,Peng Y,Ronsein GE,Bornfeldt KE,Duffield JS,Heinecke JW

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jun 05 00:00:00 EDT 2015

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.

Nature communications

Koh HS,Chang CY,Jeon SB,Yoon HJ,Ahn YH,Kim HS,Kim IH,Jeon SH,Johnson RS,Park EJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Mar 20 00:00:00 EDT 2015

Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.

Nature communications

Balasubramani A,Larjo A,Bassein JA,Chang X,Hastie RB,Togher SM,Lähdesmäki H,Rao A

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Jun 22 00:00:00 EDT 2015

Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.

PloS one

Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2016

dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.

Nature communications

Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Sep 15 00:00:00 EDT 2015

Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.

Stem cell reports

Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Oct 13 00:00:00 EDT 2015

Eosinophils from Murine Lamina Propria Induce Differentiation of Naïve T Cells into Regulatory T Cells via TGF-β1 and Retinoic Acid.

PloS one

Chen HH,Sun AH,Ojcius DM,Hu WL,Ge YM,Lin X,Li LJ,Pan JP,Yan J

13-0112 was used in Flow cytometry/Cell sorting to investigate mechanisms that induce Tregs, showing that eosinophils from murine lamina propria induce differentiation via TGF-β1 and retinoic acid.

Fri Jun 17 00:00:00 EDT 2016

Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.

Oncoimmunology

Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2015

IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.

PloS one

Carpio VH,Opata MM,Montañez ME,Banerjee PP,Dent AL,Stephens R

13-0112 was used in Flow cytometry/Cell sorting to elucidate the lineage of a specific Ifng+ CD4 T cell subset generated during Plasmodium chabaudi infection in mice.

Sun Jun 26 00:00:00 EDT 2016

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.

Nature medicine

Herranz D,Ambesi-Impiombato A,Palomero T,Schnell SA,Belver L,Wendorff AA,Xu L,Castillo-Martin M,Llobet-Navás D,Cordon-Cardo C,Clappier E,Soulier J,Ferrando AA

13-0112 was used in Flow cytometry/Cell sorting to identify N-Me as a long-range oncogenic enhancer implicated directly in the pathogenesis of human leukaemia.

Wed Oct 01 00:00:00 EDT 2014

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.

Nature

Westphalen K,Gusarova GA,Islam MN,Subramanian M,Cohen TS,Prince AS,Bhattacharya J

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Thu Feb 27 00:00:00 EST 2014

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.

Nature

Colegio OR,Chu NQ,Szabo AL,Chu T,Rhebergen AM,Jairam V,Cyrus N,Brokowski CE,Eisenbarth SC,Phillips GM,Cline GW,Phillips AJ,Medzhitov R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Sep 25 00:00:00 EDT 2014

Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.

Cell

Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Mar 13 00:00:00 EDT 2014

Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes.

Cell metabolism

Lee S,Lee HC,Kwon YW,Lee SE,Cho Y,Kim J,Lee S,Kim JY,Lee J,Yang HM,Mook-Jung I,Nam KY,Chung J,Lazar MA,Kim HS

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Tue Mar 04 00:00:00 EST 2014

Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling.

Cell host & microbe

Burberry A,Zeng MY,Ding L,Wicks I,Inohara N,Morrison SJ,Núñez G

13-0112 was used in Flow cytometry/Cell sorting to investigate how infection mobilises hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signalling.

Wed Jun 11 00:00:00 EDT 2014

A role for the ITAM signaling module in specifying cytokine-receptor functions.

Nature immunology

Bezbradica JS,Rosenstein RK,DeMarco RA,Brodsky I,Medzhitov R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Apr 01 00:00:00 EDT 2014

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.

Nature immunology

Mahmud SA,Manlove LS,Schmitz HM,Xing Y,Wang Y,Owen DL,Schenkel JM,Boomer JS,Green JM,Yagita H,Chi H,Hogquist KA,Farrar MA

13-0112 was used in Flow cytometry/Cell sorting to study the role of TNF receptors in the thymic development of Treg cells..

Thu May 01 00:00:00 EDT 2014

An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment.

Blood

Gibbins JD,Ancelet LR,Weinkove R,Compton BJ,Painter GF,Petersen TR,Hermans IF

13-0112 was used in Flow cytometry/Cell sorting to investigate the efficacy of an intravenously administered vaccine consisting of irradiated leukemia cells loaded with α-GalCer.

Thu Nov 06 00:00:00 EST 2014

Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer.

Autophagy

Guo W,Sun Y,Liu W,Wu X,Guo L,Cai P,Wu X,Wu X,Shen Y,Shu Y,Gu Y,Xu Q

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Sun Jun 01 00:00:00 EDT 2014

RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma.

Cancer research

Chen X,Zhang L,Zhang IY,Liang J,Wang H,Ouyang M,Wu S,da Fonseca ACC,Weng L,Yamamoto Y,Yamamoto H,Natarajan R,Badie B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Dec 15 00:00:00 EST 2014

Macrophages contribute to the cyclic activation of adult hair follicle stem cells.

PLoS biology

Castellana D,Paus R,Perez-Moreno M

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Dec 01 00:00:00 EST 2014

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Science signaling

Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Tue Aug 12 00:00:00 EDT 2014

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Science signaling

Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Tue Aug 12 00:00:00 EDT 2014

Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.

Glia

Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Aug 01 00:00:00 EDT 2014

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.

Development (Cambridge, England)

Gilmour J,Assi SA,Jaegle U,Kulu D,van de Werken H,Clarke D,Westhead DR,Philipsen S,Bonifer C

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Jun 01 00:00:00 EDT 2014

Dorsal raphe neuroinflammation promotes dramatic behavioral stress dysregulation.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Howerton AR,Roland AV,Bale TL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Wed May 21 00:00:00 EDT 2014

Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease.

American journal of physiology. Lung cellular and molecular physiology

Lee R,Reese C,Bonner M,Tourkina E,Hajdu Z,Riemer EC,Silver RM,Visconti RP,Hoffman S

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Tue Apr 15 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu May 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu May 01 00:00:00 EDT 2014

Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes.

Journal of immunology (Baltimore, Md. : 1950)

Geem D,Medina-Contreras O,McBride M,Newberry RD,Koni PA,Denning TL

13-0112 was used in Magnetic cell separation to investigate whether GALT and/or mesenteric lymph nodes are required for intestinal Th17 differentiation, showing that specific microbiota-induced intestinal Th17 differentiation requires MHC class II.

Tue Jul 01 00:00:00 EDT 2014

Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology.

Journal of immunology (Baltimore, Md. : 1950)

El-Zaatari M,Chang YM,Zhang M,Franz M,Shreiner A,McDermott AJ,van der Sluijs KF,Lutter R,Grasberger H,Kamada N,Young VB,Huffnagle GB,Kao JY

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Jul 15 00:00:00 EDT 2014

Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease.

Virology

Wolf AI,Strauman MC,Mozdzanowska K,Williams KL,Osborne LC,Shen H,Liu Q,Garlick D,Artis D,Hensley SE,Caton AJ,Weiser JN,Erikson J

13-0112-82 was used in Flow Cytometry to investigate severity of influenza virus response with respiratory microbe presence.

Fri Aug 01 00:00:00 EDT 2014

Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages.

Journal of neuroimmunology

Carvalho da Fonseca AC,Wang H,Fan H,Chen X,Zhang I,Zhang L,Lima FR,Badie B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Sep 15 00:00:00 EDT 2014

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.

Nature communications

Chen L,Gibbons DL,Goswami S,Cortez MA,Ahn YH,Byers LA,Zhang X,Yi X,Dwyer D,Lin W,Diao L,Wang J,Roybal J,Patel M,Ungewiss C,Peng D,Antonia S,Mediavilla-Varela M,Robertson G,Suraokar M,Welsh JW,Erez B,Wistuba II,Chen L,Peng D,Wang S,Ullrich SE,Heymach JV,Kurie JM,Qin FX

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Oct 28 00:00:00 EDT 2014

Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.

PloS one

Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu May 28 00:00:00 EDT 2015

Adeno-associated viral (AAV) vectors do not efficiently target muscle satellite cells.

Molecular therapy. Methods & clinical development

Arnett AL,Konieczny P,Ramos JN,Hall J,Odom G,Yablonka-Reuveni Z,Chamberlain JR,Chamberlain JS

13-0112 was used in Magnetic cell separation to examine the relative ability of recombinant AAV vectors derived from AAV serotype 6 to target both mature muscle cells and myogenic stem cells.

Thu Jan 04 00:00:00 EST 2024

Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.

Molecular cancer

Doloff JC,Chen CS,Waxman DJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Jun 26 00:00:00 EDT 2014

Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.

PloS one

Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Wed Jun 10 00:00:00 EDT 2015

P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.

PloS one

Monção-Ribeiro LC,Faffe DS,Santana PT,Vieira FS,da Graça CL,Marques-da-Silva C,Machado MN,Caruso-Neves C,Zin WA,Borojevic R,Takiya CM,Coutinho-Silva R

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2015

The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.

The Journal of biological chemistry

Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Feb 14 00:00:00 EST 2014

Arteriolar niches maintain haematopoietic stem cell quiescence.

Nature

Kunisaki Y,Bruns I,Scheiermann C,Ahmed J,Pinho S,Zhang D,Mizoguchi T,Wei Q,Lucas D,Ito K,Mar JC,Bergman A,Frenette PS

13-0112 was used in Flow cytometry/Cell sorting to investigate the spatial localisation of quiescent haematopoietic stem cells in bone marrow, showing that arteriolar niches maintain quiescence.

Thu Oct 31 00:00:00 EDT 2013

miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.

Nature cell biology

Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Mar 01 00:00:00 EST 2013

S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages.

Clinical cancer research : an official journal of the American Association for Cancer Research

Wang H,Zhang L,Zhang IY,Chen X,Da Fonseca A,Wu S,Ren H,Badie S,Sadeghi S,Ouyang M,Warden CD,Badie B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Jul 15 00:00:00 EDT 2013

A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils.

Developmental cell

Zhang Y,Tang W,Zhang H,Niu X,Xu Y,Zhang J,Gao K,Pan W,Boggon TJ,Toomre D,Min W,Wu D

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Oct 28 00:00:00 EDT 2013

Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm.

Journal of lipid research

Camacho M,Dilmé J,Solà-Villà D,Rodríguez C,Bellmunt S,Siguero L,Alcolea S,Romero JM,Escudero JR,Martínez-González J,Vila L

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Sun Dec 01 00:00:00 EST 2013

Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.

Journal of immunology (Baltimore, Md. : 1950)

Zook EC,Zhang S,Gerstein RM,Witte PL,Le PT

13-0112 was used in Flow cytometry/Cell sorting to report that Foxn1 is expressed in wild-type BM and overexpressed in Foxn1Tg.

Sun Dec 01 00:00:00 EST 2013

Mast cell-deficient Kit(W-sh) "Sash" mutant mice display aberrant myelopoiesis leading to the accumulation of splenocytes that act as myeloid-derived suppressor cells.

Journal of immunology (Baltimore, Md. : 1950)

Michel A,Schüler A,Friedrich P,Döner F,Bopp T,Radsak M,Hoffmann M,Relle M,Distler U,Kuharev J,Tenzer S,Feyerabend TB,Rodewald HR,Schild H,Schmitt E,Becker M,Stassen M

13-0112 was used in Flow cytometry/Cell sorting to demonstrate the broad effects that the Kit(W-sh) mutation has on key steps in myelopoiesis.

Sat Jun 01 00:00:00 EDT 2013

Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4.

Molecular and cellular biology

Yasunaga S,Ohtsubo M,Ohno Y,Saeki K,Kurogi T,Tanaka-Okamoto M,Ishizaki H,Shirai M,Mihara K,Brock HW,Miyoshi J,Takihara Y

13-0112 was used in Flow cytometry/Cell sorting to investigate the effects of Scmh1 on Geminin and Histone H2A, and the mechanisms therein.

Fri Feb 01 00:00:00 EST 2013

Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration.

The Journal of comparative neurology

Lampron A,Pimentel-Coelho PM,Rivest S

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Sun Dec 01 00:00:00 EST 2013

Inhibiting TGFβ1 has a protective effect on mouse bone marrow suppression following ionizing radiation exposure in vitro.

Journal of radiation research

Zhang H,Wang YA,Meng A,Yan H,Wang X,Niu J,Li J,Wang H

13-0112 was used in Flow cytometry/Cell sorting to examine if the TGF1 inhibitor, SB431542, can mitigate ionizing radiation-induced bone marrow suppression, showing that inhibition has a protective effect.

Mon Jul 01 00:00:00 EDT 2013

The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.

The Journal of biological chemistry

Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Fri Jul 19 00:00:00 EDT 2013

The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.

The Journal of biological chemistry

Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Fri Jul 19 00:00:00 EDT 2013

A novel probe for the non-invasive detection of tumor-associated inflammation.

Oncoimmunology

Balducci A,Wen Y,Zhang Y,Helfer BM,Hitchens TK,Meng WS,Wesa AK,Janjic JM

13-0112 was used in Flow cytometry/Cell sorting to develop a novel probe for the non-invasive detection of tumor-associated inflammation, with its feasibility demonstrated in a murine breast carcinoma model.

Fri Feb 01 00:00:00 EST 2013

Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris.

The Journal of biological chemistry

Fernandez-Castaneda A,Arandjelovic S,Stiles TL,Schlobach RK,Mowen KA,Gonias SL,Gaultier A

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Feb 15 00:00:00 EST 2013

Autophagy links inflammasomes to atherosclerotic progression.

Cell metabolism

Razani B,Feng C,Coleman T,Emanuel R,Wen H,Hwang S,Ting JP,Virgin HW,Kastan MB,Semenkovich CF

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Wed Apr 04 00:00:00 EDT 2012

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.

Blood

He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Oct 11 00:00:00 EDT 2012

Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.

The Journal of clinical investigation

Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Mon Oct 01 00:00:00 EDT 2012

Molecular imaging of very late antigen-4 (α4β1 integrin) in the premetastatic niche.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Shokeen M,Zheleznyak A,Wilson JM,Jiang M,Liu R,Ferdani R,Lam KS,Schwarz JK,Anderson CJ

13-0112 was used in Flow cytometry/Cell sorting to study bone marrow-derived cellular expression of VEGFR1 and VLA-4 in the development of a premetastatic niche.

Tue May 01 00:00:00 EDT 2012

Semaphorin 7a links nerve regeneration and inflammation in the cornea.

Investigative ophthalmology & visual science

Namavari A,Chaudhary S,Ozturk O,Chang JH,Yco L,Sonawane S,Katam N,Khanolkar V,Hallak J,Sarkar J,Jain S

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Mon Jul 09 00:00:00 EDT 2012

Global transcriptional analysis of primitive thymocytes reveals accelerated dynamics of T cell specification in fetal stages.

Immunogenetics

Belyaev NN,Biró J,Athanasakis D,Fernandez-Reyes D,Potocnik AJ

13-0112 was used in Magnetic cell separation to compare the development of T cells in foetal and adult stages, showing that adult and foetal T cell progenitors.

Wed Aug 01 00:00:00 EDT 2012

Microglial TIR-domain-containing adapter-inducing interferon-β (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-κB.

Journal of neuroinflammation

Lin S,Liang Y,Zhang J,Bian C,Zhou H,Guo Q,Xiong Y,Li S,Su B

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Fri Feb 24 00:00:00 EST 2012

Cell type-associated differences in migration, survival, and immunogenicity following grafting in CNS tissue.

Cell transplantation

Praet J,Reekmans K,Lin D,De Vocht N,Bergwerf I,Tambuyzer B,Daans J,Hens N,Goossens H,Pauwels P,Berneman Z,Van der Linden A,Ponsaerts P

13-0112-82 was used in Immunohistochemistry to indicate dependence on the cell type grafted: (i) a different degree of cell graft migration, survival, and toxicity and (ii) a different organization of the endogenous immune response.

Fri Dec 06 00:00:00 EST 2013

Induction of histiocytic sarcoma in mouse skeletal muscle.

PloS one

Liu J,Hettmer S,Milsom MD,Hofmann I,Hua F,Miller C,Bronson RT,Wagers AJ

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Thu Feb 07 00:00:00 EST 2013

Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin.

Immunity

Ichiyama K,Sekiya T,Inoue N,Tamiya T,Kashiwagi I,Kimura A,Morita R,Muto G,Shichita T,Takahashi R,Yoshimura A

13-0112 was used in Magnetic cell separation to investigate the molecular mechanisms by which TGF-beta allows Th17 cell differentiation via Smad-independent mechanisms, showing that Eomesodermin is suppressed by TGF-beta via the JNK pathway allowing differentiation.

Fri May 27 00:00:00 EDT 2011

Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis.

Blood

Libregts SF,Gutiérrez L,de Bruin AM,Wensveen FM,Papadopoulos P,van Ijcken W,Ozgür Z,Philipsen S,Nolte MA

13-0112 was used in Flow cytometry/Cell sorting to reveal a molecular mechanism by which chronic exposure to IFN-γ induces expression of IRF-1 and ultimately induces anaemia.

Thu Sep 01 00:00:00 EDT 2011

Hepatic stellate cells function as regulatory bystanders.

Journal of immunology (Baltimore, Md. : 1950)

Ichikawa S,Mucida D,Tyznik AJ,Kronenberg M,Cheroutre H

13-0112 was used in Magnetic cell separation to suggest that HSC can function as regulatory bystanders, and therefore, by promoting Tregs and suppressing Th17 differentiation, they might represent key players in the mechanism that drives liver-induced tolerance.

Sun May 15 00:00:00 EDT 2011

Clonal analysis reveals uniformity in the molecular profile and lineage potential of CCR9(+) and CCR9(-) thymus-settling progenitors.

Journal of immunology (Baltimore, Md. : 1950)

Desanti GE,Jenkinson WE,Parnell SM,Boudil A,Gautreau-Rolland L,Eksteen B,Ezine S,Lane PJ,Jenkinson EJ,Anderson G

13-0112 was used in Flow cytometry/Cell sorting to suggest that the earliest T cell progenitors represent a developmentally homogeneous progenitor pool that ensures the efficient generation of the first cohorts of T cells during thymus development.

Sun May 01 00:00:00 EDT 2011

Alterations in marginal zone macrophages and marginal zone B cells in old mice.

Journal of immunology (Baltimore, Md. : 1950)

Birjandi SZ,Ippolito JA,Ramadorai AK,Witte PL

13-0112 was used in Flow cytometry/Cell sorting to study the alterations in marginal zone macrophages and marginal zone B cells in old mice, and investigate how this may affect their ability to clear blood-borne antigens and mount an appropriate immune response.

Tue Mar 15 00:00:00 EDT 2011

IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis.

International immunology

Mori T,Miyamoto T,Yoshida H,Asakawa M,Kawasumi M,Kobayashi T,Morioka H,Chiba K,Toyama Y,Yoshimura A

13-0112 was used in Functional assays to elucidate the role of cytokines in chronic inflammation and joint destruction in rheumatoid arthritis.

Tue Nov 01 00:00:00 EDT 2011

Activation of the aryl hydrocarbon receptor during pregnancy in the mouse alters mammary development through direct effects on stromal and epithelial tissues.

Biology of reproduction

Lew BJ,Manickam R,Lawrence BP

13-0112 was used in Flow cytometry/Cell sorting to determine whether activation of the aryl hydrocarbon receptor (AHR) during pregnancy modulates mammary development.

Wed Jun 01 00:00:00 EDT 2011

PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.

PloS one

Hemmers S,Teijaro JR,Arandjelovic S,Mowen KA

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Tue Nov 15 00:00:00 EST 2011

Online nanoflow multidimensional fractionation for high efficiency phosphopeptide analysis.

Molecular & cellular proteomics : MCP

Ficarro SB,Zhang Y,Carrasco-Alfonso MJ,Garg B,Adelmant G,Webber JT,Luckey CJ,Marto JA

13-0112 was used in Flow cytometry/Cell sorting to explore two novel multidimensional fractionation strategies for the gathering of phosphoproteomics data.

Tue Nov 01 00:00:00 EDT 2011

Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition.

Brain : a journal of neurology

Vinukonda G,Csiszar A,Hu F,Dummula K,Pandey NK,Zia MT,Ferreri NR,Ungvari Z,LaGamma EF,Ballabh P

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Sun Aug 01 00:00:00 EDT 2010

Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals.

Nature immunology

Derudder E,Cadera EJ,Vahl JC,Wang J,Fox CJ,Zha S,van Loo G,Pasparakis M,Schlissel MS,Schmidt-Supprian M,Rajewsky K

13-0112 was used in Magnetic cell separation to define two distinct, consecutive phases of early B cell development that differ in their dependence on IKK-mediated NF-kappaB signaling.

Mon Jun 01 00:00:00 EDT 2009

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.

Cell stem cell

Le Grand F,Jones AE,Seale V,Scimè A,Rudnicki MA

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Jun 05 00:00:00 EDT 2009

Involvement of IQGAP3, a regulator of Ras/ERK-related cascade, in hepatocyte proliferation in mouse liver regeneration and development.

Journal of cellular physiology

Kunimoto K,Nojima H,Yamazaki Y,Yoshikawa T,Okanoue T,Tsukita S

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunofluorescence

Tue Sep 01 00:00:00 EDT 2009

Allogeneic stromal cell implantation in brain tissue leads to robust microglial activation.

Immunology and cell biology

Tambuyzer BR,Bergwerf I,De Vocht N,Reekmans K,Daans J,Jorens PG,Goossens H,Ysebaert DK,Chatterjee S,Van Marck E,Berneman ZN,Ponsaerts P

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Fri Jun 19 00:00:00 EDT 2009

Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice.

BMC biotechnology

Bergwerf I,De Vocht N,Tambuyzer B,Verschueren J,Reekmans K,Daans J,Ibrahimi A,Van Tendeloo V,Chatterjee S,Goossens H,Jorens PG,Baekelandt V,Ysebaert D,Van Marck E,Berneman ZN,Linden AV,Ponsaerts P

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Immunohistochemistry

Wed Jan 07 00:00:00 EST 2009

Identification of dendritic cell subsets responding to genital infection by Chlamydia muridarum.

FEMS immunology and medical microbiology

Moniz RJ,Chan AM,Kelly KA

13-0112 was used in Magnetic cell separation to report the activation of classical CD11b+ (cDC) and plasmacytoid (pDC) during genital infection with Chlamydia muridarum.

Sun Mar 01 00:00:00 EST 2009

Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.

Immunity

Tsuji M,Suzuki K,Kitamura H,Maruya M,Kinoshita K,Ivanov II,Itoh K,Littman DR,Fagarasan S

13-0112 was used in Flow cytometry/Cell sorting to investigate the sites and mechanisms for T cell-independent IgA synthesis.

Fri Aug 15 00:00:00 EDT 2008

Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.

Immunity

Tsuji M,Suzuki K,Kitamura H,Maruya M,Kinoshita K,Ivanov II,Itoh K,Littman DR,Fagarasan S

13-0112 was used in Flow cytometry/Cell sorting to investigate the sites and mechanisms for T cell-independent IgA synthesis.

Fri Aug 15 00:00:00 EDT 2008

Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow.

Stem cells (Dayton, Ohio)

Singh P,Yao Y,Weliver A,Broxmeyer HE,Hong SC,Chang CH

13-0112 was used in Flow cytometry/Cell sorting to show that in vivo VV infection results in the expansion of c-Kit(hi)Sca-1+Lin- (KSL) haematopoietic stem cells.

Tue Apr 01 00:00:00 EDT 2008

E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.

Journal of immunology (Baltimore, Md. : 1950)

Yang Q,Kardava L,St Leger A,Martincic K,Varnum-Finney B,Bernstein ID,Milcarek C,Borghesi L

13-0112 was used in Flow cytometry/Cell sorting to show E47 controls the developmental integrity and cell cycle quiescence of hematopoietic progenitors.

Sat Nov 01 00:00:00 EDT 2008

Unique receptor repertoire in mouse uterine NK cells.

Journal of immunology (Baltimore, Md. : 1950)

Yadi H,Burke S,Madeja Z,Hemberger M,Moffett A,Colucci F

13-0112-82 was used in Flow Cytometry to define the receptor repertoire and phenotype of uterine NK cells at mid-gestation in mice.

Sat Nov 01 00:00:00 EDT 2008

Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.

The Journal of biological chemistry

Chen Y,Wang X,Di L,Fu G,Chen Y,Bai L,Liu J,Feng X,McDonald JM,Michalek S,He Y,Yu M,Fu YX,Wen R,Wu H,Wang D

Published figure using CD11b monoclonal antibody (Product # 13-0112-82) in Flow Cytometry

Fri Oct 24 00:00:00 EDT 2008

Murine CXCL14 is dispensable for dendritic cell function and localization within peripheral tissues.

Molecular and cellular biology

Meuter S,Schaerli P,Roos RS,Brandau O,Bösl MR,von Andrian UH,Moser B

13-0112 was used in Flow cytometry/Cell sorting to investigate the process of dendritic cell recruitment to peripheral tissues, showing that murine CXCL14 is dispensable for dendritic cell function and localisation.

Thu Feb 01 00:00:00 EST 2007

Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells.

Immunity

Mukai K,Matsuoka K,Taya C,Suzuki H,Yokozeki H,Nishioka K,Hirokawa K,Etori M,Yamashita M,Kubota T,Minegishi Y,Yonekawa H,Karasuyama H

13-0112 was used in Flow cytometry/Cell sorting to reveal a novel basophil-induced mechanism of development of chronic allergic inflammation.

Mon Aug 01 00:00:00 EDT 2005

Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling.

Genes & development

Taghon TN,David ES,Zúñiga-Pflücker JC,Rothenberg EV

13-0112 was used in Flow cytometry/Cell sorting to study how Notch/Delta signaling is not sufficient for T-lineage specification and commitment, but can be permissive for the maintenance and proliferation of uncommitted progenitors.

Fri Apr 15 00:00:00 EDT 2005

Bioinformatics

Protein Aliases: CD11 antigen-like family member B; CD11B (p170); cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component receptor 3 alpha-a; complement receptor type 3; CR-3 alpha chain; integrin alpha-M; leukocyte adhesion receptor MO1; Mac-1 alpha; Mac-1 alpha (Mac1A); macrophage antigen alpha; MGC117044

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Gene Aliases: Cd11b; CD11b/CD18; CR3; CR3A; F730045J24Rik; Ly-40; Mac-1; Mac-1a; MAC1

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Entrez Gene ID: (Mouse) 16409

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Function(s)

opsonin binding glycoprotein binding heparin binding heparan sulfate proteoglycan binding metal ion binding protein heterodimerization activity integrin

Process(es)

leukocyte migration involved in inflammatory response cell adhesion leukocyte cell-cell adhesion integrin-mediated signaling pathway microglia development single organismal cell-cell adhesion neutrophil chemotaxis cellular extravasation activated T cell proliferation

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CD11b Monoclonal Antibody (M1/70), Biotin, eBioscience™

CD11b Antibody (13-0112-82) in Flow

Product Details

13-0112-82

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Neutralization (Neu)

Functional Assay (Functional)

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Recommended Isotype Control

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