Product References
Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation.
Cell reports
Meyers AK,Wang Z,Han W,Zhao Q,Zabalawi M,Duan L,Liu J,Zhang Q,Manne RK,Lorenzo F,Quinn MA,Song Q,Fan D,Lin HK,Furdui CM,Locasale JW,McCall CE,Zhu X
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Tue Jan 31 00:00:00 EST 2023
Platelets exacerbate cardiovascular inflammation in a murine model of Kawasaki disease vasculitis.
JCI insight
Kocatürk B,Lee Y,Nosaka N,Abe M,Martinon D,Lane ME,Moreira D,Chen S,Fishbein MC,Porritt RA,Franklin BS,Noval Rivas M,Arditi M
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Jul 24 00:00:00 EDT 2023
Pexidartinib synergize PD-1 antibody through inhibiting treg infiltration by reducing TAM-derived CCL22 in lung adenocarcinoma.
Frontiers in pharmacology
Zhang W,Jiang X,Zou Y,Yuan L,Wang X
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Tue Mar 28 00:00:00 EDT 2023
MARCH3 negatively regulates IL-3-triggered inflammatory response by mediating K48-linked polyubiquitination and degradation of IL-3Rα.
Signal transduction and targeted therapy
Feng L,Li C,Zeng LW,Gao D,Sun YH,Zhong L,Lin H,Shu HB,Li S
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling.
The Journal of biological chemistry
Yan Q,Gao H,Yao Q,Ling K,Xiao G
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
Lysosomal acid lipase, CSF1R, and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells.
JCI insight
Zhao T,Liu S,Ding X,Johnson EM,Hanna NH,Singh K,Sen CK,Wan J,Du H,Yan C
14-1152-82 was used in Inhibition Assays, Flow Cytometry to investigate if CD11c+ cells switched their functions to immune suppression and tumor growth stimulation through CSF1R/PD-L1 upregulation and metabolic reprogramming.
Thu Sep 08 00:00:00 EDT 2022
Lysosomal acid lipase, CSF1R, and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells.
JCI insight
Zhao T,Liu S,Ding X,Johnson EM,Hanna NH,Singh K,Sen CK,Wan J,Du H,Yan C
14-1152-82 was used in Inhibition Assays, Flow Cytometry to investigate if CD11c+ cells switched their functions to immune suppression and tumor growth stimulation through CSF1R/PD-L1 upregulation and metabolic reprogramming.
Thu Sep 08 00:00:00 EDT 2022
Erythropoietin Receptor (EPOR) Signaling in the Osteoclast Lineage Contributes to EPO-Induced Bone Loss in Mice.
International journal of molecular sciences
Awida Z,Hiram-Bab S,Bachar A,Saed H,Zyc D,Gorodov A,Ben-Califa N,Omari S,Omar J,Younis L,Iden JA,Graniewitz Visacovsky L,Gluzman I,Liron T,Raphael-Mizrahi B,Kolomansky A,Rauner M,Wielockx B,Gabet Y,Neumann D
14-1152-82 was used in Flow cytometry/Cell sorting to define the role of monocyte EPOR in EPO-mediated bone loss, by using two mouse lines with conditional deletion of EPOR in the monocytic lineage.
Mon Oct 10 00:00:00 EDT 2022
Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.
The EMBO journal
Wieghofer P,Hagemeyer N,Sankowski R,Schlecht A,Staszewski O,Amann L,Gruber M,Koch J,Hausmann A,Zhang P,Boneva S,Masuda T,Hilgendorf I,Goldmann T,Böttcher C,Priller J,Rossi FM,Lange C,Prinz M
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Mar 15 00:00:00 EDT 2021
Low-dose 2-deoxy glucose stabilises tolerogenic dendritic cells and generates potent in vivo immunosuppressive effects.
Cellular and molecular life sciences : CMLS
Christofi M,Le Sommer S,Mölzer C,Klaska IP,Kuffova L,Forrester JV
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
HOXA11 plays critical roles in disease progression and response to cytarabine in AML.
Oncology reports
Fu JF,Shih LY,Yen TH
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.
Journal of neuroinflammation
Oladiran O,Shi XQ,Yang M,Fournier S,Zhang J
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Mar 22 00:00:00 EDT 2021
CX3CR1 But Not CCR2 Expression Is Required for the Development of Autoimmune Peripheral Neuropathy in Mice.
Frontiers in immunology
Oladiran O,Shi XQ,Fournier S,Zhang J
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Tue Dec 21 00:00:00 EST 2021
Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics.
eLife
Serrano-Lopez J,Hegde S,Kumar S,Serrano J,Fang J,Wellendorf AM,Roche PA,Rangel Y,Carrington LJ,Geiger H,Grimes HL,Luther S,Maillard I,Sanchez-Garcia J,Starczynowski DT,Cancelas JA
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Thu Apr 08 00:00:00 EDT 2021
Hepatocyte-specific glucose-6-phosphatase deficiency disturbs platelet aggregation and decreases blood monocytes upon fasting-induced hypoglycemia.
Molecular metabolism
La Rose AM,Bazioti V,Hoogerland JA,Svendsen AF,Groenen AG,van Faassen M,Rutten MGS,Kloosterhuis NJ,Dethmers-Ausema B,Nijland JH,Mithieux G,Rajas F,Kuipers F,Lukens MV,Soehnlein O,Oosterveer MH,Westerterp M
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in Mice.
International journal of molecular sciences
Awida Z,Bachar A,Saed H,Gorodov A,Ben-Califa N,Ibrahim M,Kolomansky A,Iden JA,Graniewitz Visacovsky L,Liron T,Hiram-Bab S,Brines M,Gabet Y,Neumann D
14-1152-82 was used in Flow cytometry/Cell sorting to evaluate the role of the heteromeric complex in bone metabolism in vivo and in vitro by using Cibinetide (CIB), a non-erythropoietic EPO analogue that exclusively binds the heteromeric receptor.
Tue Dec 21 00:00:00 EST 2021
Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.
PLoS biology
Xiao J,Wang C,Yao JC,Alippe Y,Yang T,Kress D,Sun K,Kostecki KL,Monahan JB,Veis DJ,Abu-Amer Y,Link DC,Mbalaviele G
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.
Glia
Boeck M,Thien A,Wolf J,Hagemeyer N,Laich Y,Yusuf D,Backofen R,Zhang P,Boneva S,Stahl A,Hilgendorf I,Agostini H,Prinz M,Wieghofer P,Schlunck G,Schlecht A,Lange C
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Androgen Receptor Signaling Positively Regulates Monocytic Development.
Frontiers in immunology
Consiglio CR,Gollnick SO
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Thu Apr 29 00:00:00 EDT 2021
Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection.
Science advances
Park MY,Kim HS,Lee HY,Zabel BA,Bae YS
14-1152-82 was used in Flow Cytometry to find a previously unidentified pathogenic CD11b+Gr-1+ myeloid cell population that expresses stem cell antigen-1 (Sca-1) induced upon experimental infection with Staphylococcus aureus.
Wed Jan 01 00:00:00 EST 2020
Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking.
The Journal of clinical investigation
Zhang J,Supakorndej T,Krambs JR,Rao M,Abou-Ezzi G,Ye RY,Li S,Trinkaus K,Link DC
14-1152 was used in Flow cytometry/Cell sorting to show that HSPC mobilization after cDC ablation is attenuated in mice lacking CXCR2 expression.
Tue Apr 30 00:00:00 EDT 2019
Concomitant type I IFN and M-CSF signaling reprograms monocyte differentiation and drives pro-tumoral arginase production.
EBioMedicine
Tong Y,Zhou L,Yang L,Guo P,Cao Y,Qin FX,Liu J
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
Circuit Design Features of a Stable Two-Cell System.
Cell
Zhou X,Franklin RA,Adler M,Jacox JB,Bailis W,Shyer JA,Flavell RA,Mayo A,Alon U,Medzhitov R
14-1152 was used in Flow cytometry/Cell sorting to illustrate principles of cell circuit design and provide a quantitative perspective on cell interactions.
Thu Feb 08 00:00:00 EST 2018
Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes.
Journal of cellular physiology
Liron T,Raphael B,Hiram-Bab S,Bab IA,Gabet Y
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Captopril mitigates splenomegaly and myelofibrosis in the Gata1low murine model of myelofibrosis.
Journal of cellular and molecular medicine
Corey SJ,Jha J,McCart EA,Rittase WB,George J,Mattapallil JJ,Mehta H,Ognoon M,Bylicky MA,Summers TA,Day RM
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation.
Molecular and cellular biology
Tang J,Frey JM,Wilson CL,Moncada-Pazos A,Levet C,Freeman M,Rosenfeld ME,Stanley ER,Raines EW,Bornfeldt KE
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways.
Molecular and cellular biology
Baba O,Horie T,Nakao T,Hakuno D,Nakashima Y,Nishi H,Kuwabara Y,Nishiga M,Nishino T,Ide Y,Nakazeki F,Koyama S,Kimura M,Hanada R,Kawahara M,Kimura T,Ono K
14-1152 was used in Flow cytometry/Cell sorting to indicate that miR-33 deficiency affects distribution of inflammatory monocytes through dual pathways.
Sun Jul 15 00:00:00 EDT 2018
Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling.
Journal of diabetes research
Jin X,Liu L,Zhang Y,Xiang Y,Yin G,Lu Y,Shi L,Dong J,Shen C
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Wed Oct 10 00:00:00 EDT 2018
LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux.
Cell reports
Thomas DG,Doran AC,Fotakis P,Westerterp M,Antonson P,Jiang H,Jiang XC,Gustafsson JÅ,Tabas I,Tall AR
14-1152 was used in Flow cytometry/Cell sorting to study the mechanisms underlying the repressive activity of liver X receptor.
Wed Dec 26 00:00:00 EST 2018
Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report.
Arteriosclerosis, thrombosis, and vascular biology
de Jong RJ,Paulin N,Lemnitzer P,Viola JR,Winter C,Ferraro B,Grommes J,Weber C,Reutelingsperger C,Drechsler M,Soehnlein O
14115282 was used in flow cytometry to examine the role of the proresolving protein annexin A1 in healing after wire injury
Wed Feb 01 00:00:00 EST 2017
CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.
Mucosal immunology
Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z
14-1152 was used in Neutralization experiments to show that there are two unique macrophage populations present in the cornea, which both participate in corneal wound healing.
Fri Sep 01 00:00:00 EDT 2017
Local Group 2 Innate Lymphoid Cells Promote Corneal Regeneration after Epithelial Abrasion.
The American journal of pathology
Liu J,Xiao C,Wang H,Xue Y,Dong D,Lin C,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z
14-1152-82 was used in Immunodepletion to reveal the critical role of cornea-resident group 2 innate lymphoid cells in restoring corneal epithelial integrity after acute injury.
Thu Jun 01 00:00:00 EDT 2017
Erythropoietin enhances Kupffer cell number and activity in the challenged liver.
Scientific reports
Gilboa D,Haim-Ohana Y,Deshet-Unger N,Ben-Califa N,Hiram-Bab S,Reuveni D,Zigmond E,Gassmann M,Gabet Y,Varol C,Neumann D
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Sep 04 00:00:00 EDT 2017
Erythro-myeloid progenitors can differentiate from endothelial cells and modulate embryonic vascular remodeling.
Scientific reports
Kasaai B,Caolo V,Peacock HM,Lehoux S,Gomez-Perdiguero E,Luttun A,Jones EA
14115282 was used in flow cytometry to show erythro-myeloid progenitors directly differentiate into endothelial cells
Wed Mar 08 00:00:00 EST 2017
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.
Nature medicine
Theurl I,Hilgendorf I,Nairz M,Tymoszuk P,Haschka D,Asshoff M,He S,Gerhardt LM,Holderried TA,Seifert M,Sopper S,Fenn AM,Anzai A,Rattik S,McAlpine C,Theurl M,Wieghofer P,Iwamoto Y,Weber GF,Harder NK,Chousterman BG,Arvedson TL,McKee M,Wang F,Lutz OM,Rezoagli E,Babitt JL,Berra L,Prinz M,Nahrendorf M,Weiss G,Weissleder R,Lin HY,Swirski FK
14115282 was used in flow cytometry to discover a mechanism that clears erythrocytes and recycles iron
Mon Aug 01 00:00:00 EDT 2016
Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment.
Nature
Dong L,Yu WM,Zheng H,Loh ML,Bunting ST,Pauly M,Huang G,Zhou M,Broxmeyer HE,Scadden DT,Qu CK
14115282 was used in immunohistochemistry - frozen section to elucidate the contribution of Ptpn11 mutations in the bone marrow microenvironment to leukaemogenesis
Thu Nov 10 00:00:00 EST 2016
The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells.
Immunity
Ho SS,Zhang WY,Tan NY,Khatoo M,Suter MA,Tripathi S,Cheung FS,Lim WK,Tan PH,Ngeow J,Gasser S
14-1152 was used in Blocking experiments to demonstrate that MUS81 alerts the immune system to the presence of transformed host cells.
Tue May 17 00:00:00 EDT 2016
PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia.
The Journal of clinical investigation
Cole CB,Verdoni AM,Ketkar S,Leight ER,Russler-Germain DA,Lamprecht TL,Demeter RT,Magrini V,Ley TJ
14115282 was used in flow cytometry to study how DNMT3A is involved in the function of PML-RARA, RUNX1-RUNX1T1, and MLL-AF9
Fri Jan 01 00:00:00 EST 2016
M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation.
The Journal of experimental medicine
Kandalla PK,Sarrazin S,Molawi K,Berruyer C,Redelberger D,Favel A,Bordi C,de Bentzmann S,Sieweke MH
14-1152 was used in Flow cytometry/Cell sorting to study the role of M-CSF in the protection against pathogens after hematopoietic stem/progenitor cell transplantation.
Mon Oct 17 00:00:00 EDT 2016
Enforced Expression of Hoxa3 Inhibits Classical and Promotes Alternative Activation of Macrophages In Vitro and In Vivo.
Journal of immunology (Baltimore, Md. : 1950)
Al Sadoun H,Burgess M,Hentges KE,Mace KA
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice.
Cell death & disease
Wang T,Wang Z,Yang P,Xia L,Zhou M,Wang S,Du J,Zhang J
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Thu Apr 07 00:00:00 EDT 2016
PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications.
Nature communications
Lancaster GI,Kammoun HL,Kraakman MJ,Kowalski GM,Bruce CR,Febbraio MA
14-1152 was used in Flow cytometry/Cell sorting to examine the role of protein kinase R in the development of obesity and its associated metabolic complications in vivo as well as its putative lipid-sensing role in vitro.
Wed Feb 03 00:00:00 EST 2016
Accelerating skin wound healing by M-CSF through generating SSEA-1 and -3 stem cells in the injured sites.
Scientific reports
Li Y,Jalili RB,Ghahary A
14-1152 was used in Immunofluorescence to demonstrate that M-CSF induces hematopoietic cell dedifferentiation into SSEA-1 and -3 stem cells, accelerating skin wound healing.
Fri Jul 01 00:00:00 EDT 2016
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Nature
Carmi Y,Spitzer MH,Linde IL,Burt BM,Prestwood TR,Perlman N,Davidson MG,Kenkel JA,Segal E,Pusapati GV,Bhattacharya N,Engleman EG
14-1152 was used in Flow cytometry/Cell sorting to find that allogeneic tumour rejection is initiated in mice by naturally occurring tumour-binding IgG antibodies.
Thu May 07 00:00:00 EDT 2015
Promoting macrophage survival delays progression of pre-existing atherosclerotic lesions through macrophage-derived apoE.
Cardiovascular research
Bouchareychas L,Pirault J,Saint-Charles F,Deswaerte V,Le Roy T,Jessup W,Giral P,Le Goff W,Huby T,Gautier EL,Lesnik P
14-1152 was used in Flow cytometry/Cell sorting to determine whether macrophages resistant to apoptosis have a therapeutic impact on pre-existing atherosclerotic lesions, and by what mechanisms they achieve protection.
Thu Oct 01 00:00:00 EDT 2015
Redefining Myeloid Cell Subsets in Murine Spleen.
Frontiers in immunology
Hey YY,Tan JK,O'Neill HC
14-1152 was used in Flow cytometry/Cell sorting to identify and fully characterize a novel splenic subset termed "L-DC" in relation to other myeloid cells.
Thu Jan 21 00:00:00 EST 2016
Immune surveillance of the lung by migrating tissue monocytes.
eLife
Rodero MP,Poupel L,Loyher PL,Hamon P,Licata F,Pessel C,Hume DA,Combadière C,Boissonnas A
14-1152 was used in Flow cytometry/Cell sorting to compare the contribution of monocytes to innate immune surveillance of the lung in the steady state with macrophage and dendritic cells.
Mon Jul 13 00:00:00 EDT 2015
Macrophages Subvert Adaptive Immunity to Urinary Tract Infection.
PLoS pathogens
Mora-Bau G,Platt AM,van Rooijen N,Randolph GJ,Albert ML,Ingersoll MA
14-1152 was used in Flow cytometry/Cell sorting to suggest that bacterial uptake by tissue macrophages impedes development of adaptive immune responses during urinary tract infection.
Wed Jul 01 00:00:00 EDT 2015
The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection.
PLoS pathogens
Dalton JE,Glover AC,Hoodless L,Lim EK,Beattie L,Kirby A,Kaye PM
14-1152 was used in Flow cytometry/Cell sorting to investigate how Ntrk2 plays a role in the pathologic remodeling of the spleen that accompanies chronic infection.
Sun Feb 01 00:00:00 EST 2015
Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation.
PloS one
Mandl M,Drechsler M,Jansen Y,Neideck C,Noels H,Faussner A,Soehnlein O,Weber C,Döring Y
14-1152 was used in Flow cytometry/Cell sorting to investigate how continuous diphtheria toxin-induced pDC depletion in Apoe-/- BDCA2-DTR mice receiving a high-fat diet (HFD) for 4 weeks did not alter lesion size or composition.
Sun May 08 00:00:00 EDT 2016
Progressive replacement of embryo-derived cardiac macrophages with age.
The Journal of experimental medicine
Molawi K,Wolf Y,Kandalla PK,Favret J,Hagemeyer N,Frenzel K,Pinto AR,Klapproth K,Henri S,Malissen B,Rodewald HR,Rosenthal NA,Bajenoff M,Prinz M,Jung S,Sieweke MH
14-1152 was used in Flow cytometry/Cell sorting to report that the embryo-derived population of cardiac macrophages is progressively substituted for monocyte-derived macrophages within the first weeks after birth.
Mon Oct 20 00:00:00 EDT 2014
Distinct progenitor origin distinguishes a lineage of dendritic-like cells in spleen.
Frontiers in immunology
Petvises S,O'Neill HC
14-1152 was used in Flow cytometry/Cell sorting to study how a lineage of dendritic-like cells in the spleen are distinguished by distinct progenitor origins.
Wed Jan 15 00:00:00 EST 2014
Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcγRI.
Journal of leukocyte biology
Pilling D,Crawford JR,Verbeek JS,Gomer RH
14-1152 was used in Flow cytometry/Cell sorting to suggest that IgG-mediated inhibition of fibrocyte differentiation is mediated by FcRs.
Fri Aug 01 00:00:00 EDT 2014
Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection.
Immunology and cell biology
Filbey KJ,Grainger JR,Smith KA,Boon L,van Rooijen N,Harcus Y,Jenkins S,Hewitson JP,Maizels RM
14-1152 was used in Flow cytometry/Cell sorting to study the differential levels of resistance to the nematode, H. polygyrus, that are observable between mouse models.
Wed Jan 07 00:00:00 EST 2015
Delivery of CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages.
Journal of cell science
Lou J,Low-Nam ST,Kerkvliet JG,Hoppe AD
14-1152-82 was used in Immunocytochemistry to show that internalisation of CSF-1R in small endocytic vesicles outcompetes CSF-1R endocytosis via macropinocytosis.
Mon Dec 15 00:00:00 EST 2014
Delivery of CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages.
Journal of cell science
Lou J,Low-Nam ST,Kerkvliet JG,Hoppe AD
14-1152-82 was used in Immunocytochemistry to show that internalisation of CSF-1R in small endocytic vesicles outcompetes CSF-1R endocytosis via macropinocytosis.
Mon Dec 15 00:00:00 EST 2014
CD3 antibody and IL-2 complex combination therapy inhibits atherosclerosis by augmenting a regulatory immune response.
Journal of the American Heart Association
Kasahara K,Sasaki N,Yamashita T,Kita T,Yodoi K,Sasaki Y,Takeda M,Hirata K
14-1152 was used in Flow cytometry/Cell sorting to investigate the inhibition of atherosclerosis by a CD3 antibody and IL-2 complex combination.
Tue Apr 22 00:00:00 EDT 2014
The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration.
PloS one
Sauter KA,Pridans C,Sehgal A,Bain CC,Scott C,Moffat L,Rojo R,Stutchfield BM,Davies CL,Donaldson DS,Renault K,McColl BW,Mowat AM,Serrels A,Frame MC,Mabbott NA,Hume DA
14-1152 was used in Flow cytometry/Cell sorting to examine expression of the MacBlue transgene in embryos and adult mice.
Fri Dec 18 00:00:00 EST 2015
IL-3 and CSF-1 interact to promote generation of CD11c+ IL-10-producing macrophages.
PloS one
Sheng KC,Herrero LJ,Taylor A,Hapel AJ,Mahalingam S
14-1152 was used in Blocking experiments to investigate the mechanisms of regulation of hematopoiesis.
Tue Dec 30 00:00:00 EST 2014
Natural killer cells are required for extramedullary hematopoiesis following murine cytomegalovirus infection.
Cell host & microbe
Jordan S,Ruzsics Z,Mitrović M,Baranek T,Arapović J,Krmpotić A,Vivier E,Dalod M,Jonjić S,Dölken L,Koszinowski UH
14-1152 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms of extramedullary hematopoiesis.
Wed May 15 00:00:00 EDT 2013
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.
Nature cell biology
Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.
The Journal of experimental medicine
Gautier EL,Westerterp M,Bhagwat N,Cremers S,Shih A,Abdel-Wahab O,Lütjohann D,Randolph GJ,Levine RL,Tall AR,Yvan-Charvet L
14-1152 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms leading to high metabolic rate in myeloproliferative disorders, showing that HDL and Glut1 inhibition reverse hypermetabolic state.
Mon Feb 11 00:00:00 EST 2013
Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease.
The Journal of biological chemistry
McMahan RH,Wang XX,Cheng LL,Krisko T,Smith M,El Kasmi K,Pruzanski M,Adorini L,Golden-Mason L,Levi M,Rosen HR
14-1152 was used in Flow cytometry/Cell sorting to demonstrate that FXR/TGR5 activation coordinates the immune phenotype of monocytes and macrophages.
Fri Apr 26 00:00:00 EDT 2013
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.
Blood
He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Immunofluorescence
Thu Oct 11 00:00:00 EDT 2012
Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function.
Blood
Schuettpelz LG,Gopalan PK,Giuste FO,Romine MP,van Os R,Link DC
14-1152 was used in Flow cytometry/Cell sorting to investigate the role of kruppel-like factor 7 in hematopoietic stem and progenitor cell function.
Thu Oct 11 00:00:00 EDT 2012
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.
The Journal of experimental medicine
Billiard F,Lobry C,Darrasse-Jèze G,Waite J,Liu X,Mouquet H,DaNave A,Tait M,Idoyaga J,Leboeuf M,Kyratsous CA,Burton J,Kalter J,Klinakis A,Zhang W,Thurston G,Merad M,Steinman RM,Murphy AJ,Yancopoulos GD,Aifantis I,Skokos D
14-1152 was used in Flow cytometry/Cell sorting to investigate how Dll4-Notch signaling affects pro-T cell fate and thymic DC development, showing that it is a novel Flt3-independent pathway for DC development and autoimmunity.
Mon May 07 00:00:00 EDT 2012
Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Courtial N,Smink JJ,Kuvardina ON,Leutz A,Göthert JR,Lausen J
14-1152 was used in Flow cytometry/Cell sorting to show that Tal1 is expressed in osteoclasts and that loss of Tal1 in osteoclast progenitors leads to altered expression of >1200 genes.
Wed Feb 01 00:00:00 EST 2012
Homing and adhesion patterns determine the cellular composition of the bone marrow plasma cell niche.
Journal of immunology (Baltimore, Md. : 1950)
Belnoue E,Tougne C,Rochat AF,Lambert PH,Pinschewer DD,Siegrist CA
14-1152 was used in Flow cytometry/Cell sorting to better define plasma cell survival niches and their functioning.
Wed Feb 01 00:00:00 EST 2012
The TRPM4 channel controls monocyte and macrophage, but not neutrophil, function for survival in sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Serafini N,Dahdah A,Barbet G,Demion M,Attout T,Gautier G,Arcos-Fajardo M,Souchet H,Jouvin MH,Vrtovsnik F,Kinet JP,Benhamou M,Monteiro RC,Launay P
14-1152 was used in Flow cytometry/Cell sorting to show that the tight control of Ca2+ influx by the TRPM4 channel is critical for functioning of monocytes/macrophages.
Mon Oct 01 00:00:00 EDT 2012
Fos plays an essential role in the upregulation of RANK expression in osteoclast precursors within the bone microenvironment.
Journal of cell science
Arai A,Mizoguchi T,Harada S,Kobayashi Y,Nakamichi Y,Yasuda H,Penninger JM,Yamada K,Udagawa N,Takahashi N
14-1152 was used in Neutralization experiments to examine the role of Fos in RANK expression in osteoclast precursors.
Fri Jun 15 00:00:00 EDT 2012
In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.
PloS one
Pello OM,Chèvre R,Laoui D,De Juan A,Lolo F,Andrés-Manzano MJ,Serrano M,Van Ginderachter JA,Andrés V
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Mon Feb 25 00:00:00 EST 2013
Hypoxia enhances the proliferative response of macrophages to CSF-1 and their pro-survival response to TNF.
PloS one
Hamilton JA,Lacey DC,Turner A,de Kok B,Huynh J,Scholz GM
14-1152 was used in Western Blotting to examine the effects of hypoxia on the macrophage response to CSF-1 and TNF.
Thu Feb 28 00:00:00 EST 2013
An intracameral injection of antigen induces in situ chemokines and cytokines required for the generation of circulating immunoregulatory monocytes.
PloS one
Pais R,Bhowmick S,Chattopadhyay S,Lemire Y,Sharafieh R,Yadav R,O'Rourke J,Cone RE
14-1152 was used in Flow cytometry/Cell sorting to further suggest that anterior chamber-associated immune deviation is initiated as the result of a mild proinflammatory response to intracameral injection.
Wed May 01 00:00:00 EDT 2013
Pasteurella multocida toxin-stimulated osteoclast differentiation is B cell dependent.
Infection and immunity
Hildebrand D,Heeg K,Kubatzky KF
14-1152 was used in Flow cytometry/Cell sorting to suggest that the osteoclastic properties characteristic for PMT may result from a cross talk between bone cells and lymphoid cells.
Sat Jan 01 00:00:00 EST 2011
Comparison of gene expression profiles between human and mouse monocyte subsets.
Blood
Ingersoll MA,Spanbroek R,Lottaz C,Gautier EL,Frankenberger M,Hoffmann R,Lang R,Haniffa M,Collin M,Tacke F,Habenicht AJ,Ziegler-Heitbrock L,Randolph GJ
14-1152 was used in Flow cytometry/Cell sorting to identify how human and mouse monocyte subsets are far more broadly conserved than currently recognised.
Thu Jan 21 00:00:00 EST 2010
Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice.
The Journal of clinical investigation
Kovacic JC,Gupta R,Lee AC,Ma M,Fang F,Tolbert CN,Walts AD,Beltran LE,San H,Chen G,St Hilaire C,Boehm M
Fri Jan 01 00:00:00 EST 2010
Mycobacterium bovis bacillus Calmette-Guérin vaccination mobilizes innate myeloid-derived suppressor cells restraining in vivo T cell priming via IL-1R-dependent nitric oxide production.
Journal of immunology (Baltimore, Md. : 1950)
Martino A,Badell E,Abadie V,Balloy V,Chignard M,Mistou MY,Combadière B,Combadière C,Winter N
14-1152 was used in Flow cytometry/Cell sorting to show that the BCG vaccination recruits innate myeloid-derived suppressor cells, akin to mouse tumor-infiltrating cells.
Mon Feb 15 00:00:00 EST 2010
Role of Cdk4 in lymphocyte function and allergen response.
Cell cycle (Georgetown, Tex.)
Chow YH,Zhu XD,Liu L,Schwartz BR,Huang XZ,Harlan JM,Schnapp LM
14-1152 was used in Flow cytometry/Cell sorting to characterise the development and function of hematopoietic cells in Cdk4(-/-) mice and to assess the response of Cdk4(-/-) mice to allergen challenge.
Wed Dec 15 00:00:00 EST 2010
Effects of TCDD on the fate of naive dendritic cells.
Toxicological sciences : an official journal of the Society of Toxicology
Bankoti J,Burnett A,Navarro S,Miller AK,Rase B,Shepherd DM
14-1152 was used in Flow cytometry/Cell sorting to investigate whether 2,3,7,8-tetrachlorodibenzo-p-dioxin alters dendritic cell homeostasis in mice.
Tue Jun 01 00:00:00 EDT 2010
The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues.
Nature immunology
Waskow C,Liu K,Darrasse-Jèze G,Guermonprez P,Ginhoux F,Merad M,Shengelia T,Yao K,Nussenzweig M
14-1152-82 was used in Immunohistochemistry to investigate the hematopoietic growth factors regulating dendritic development.
Sun Jun 01 00:00:00 EDT 2008
The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues.
Nature immunology
Waskow C,Liu K,Darrasse-Jèze G,Guermonprez P,Ginhoux F,Merad M,Shengelia T,Yao K,Nussenzweig M
14-1152-82 was used in Immunohistochemistry to investigate the hematopoietic growth factors regulating dendritic development.
Sun Jun 01 00:00:00 EDT 2008
Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice.
The Journal of clinical investigation
Jin W,Chang M,Paul EM,Babu G,Lee AJ,Reiley W,Wright A,Zhang M,You J,Sun SC
14-1152 was used in Flow cytometry/Cell sorting to establish the CYLD enzyme as a crucial negative regulator of osteoclastogenesis and suggest its involvement in the p62/TRAF6 signaling axis.
Thu May 01 00:00:00 EDT 2008
The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease.
The Journal of experimental medicine
Carlson T,Kroenke M,Rao P,Lane TE,Segal B
14-1152 was used in Flow cytometry/Cell sorting to demonstrate that ELR(+) CXC chemokines and CXCR2-expressing polymorphonuclear leukocytes are required for the development of experimental autoimmune encephalomyelitis.
Mon Apr 14 00:00:00 EDT 2008
Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.
The Journal of biological chemistry
Chen Y,Wang X,Di L,Fu G,Chen Y,Bai L,Liu J,Feng X,McDonald JM,Michalek S,He Y,Yu M,Fu YX,Wen R,Wu H,Wang D
Published figure using CD115 (c-fms) monoclonal antibody (Product # 14-1152-82) in Flow Cytometry
Fri Oct 24 00:00:00 EDT 2008
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment.
Immunity
Nagai Y,Garrett KP,Ohta S,Bahrun U,Kouro T,Akira S,Takatsu K,Kincade PW
14-1152 was used in Flow cytometry/Cell sorting to investigate the expression of toll-like receptors on different hematopoietic stem cells and the mechanism by which they stimulate innate immune system replenishment.
Thu Jun 01 00:00:00 EDT 2006
-Flow-20170216130641.jpg?time=20220826 "CD115 (c-fms) Antibody in Flow Cytometry (Flow)")
-Flow-20170216130641.jpg?time=20220826)
-Flow-20170216130641.jpg?time=20220826?time=20220826 "CD115 (c-fms) Antibody (14-1152-82) in Flow")
