Product References
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2024
YAP/STAT3 inhibited CD8+ T cells activity in the breast cancer immune microenvironment by inducing M2 polarization of tumor-associated macrophages.
Cancer medicine
Wang C,Shen N,Guo Q,Tan X,He S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
B cell extracellular vesicles contain monomeric IgM that binds antigen and enters target cells.
iScience
Gutknecht MF,Holodick NE,Rothstein TL
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Sep 15 00:00:00 EDT 2023
Subconjunctival injection of human umbilical cord mesenchymal stem cells alleviates experimental allergic conjunctivitis via regulating T cell response.
Stem cell research & therapy
Li D,Ou Q,Shen Q,Lu MM,Xu JY,Jin C,Gao F,Wang J,Zhang J,Zhang J,Li J,Lu L,Xu GT,Tian H
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Oct 02 00:00:00 EDT 2023
Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge.
Biomaterials
Sun S,Li E,Zhao G,Tang J,Zuo Q,Cai L,Xu C,Sui C,Ou Y,Liu C,Li H,Ding Y,Li C,Lu D,Zhang W,Luo P,Cheng P,Gao Y,Tu C,Pitard B,Rosenecker J,Wang B,Liu Y,Zou Q,Guan S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2023
HSF1 promotes CD69+ Treg differentiation to inhibit colitis progression.
Theranostics
Yu L,Zhou B,Zhu Y,Li L,Zhong Y,Zhu L,Wang H,Chen H,Xu J,Guo T,Feng L,Wang X,Cai Z,Wang J,Jin H
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Apr 18 00:00:00 EDT 2023
Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-like Autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Hodgson R,Crockford TL,Bhandari A,Kepple JD,Back J,Cawthorne E,Abeler-Dörner L,Laing AG,Clare S,Speak A,Adams DJ,Dougan G,Hayday AC,Deobagkar-Lele M,Cornall RJ,Bull KR
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting.
Frontiers in immunology
Clubb JHA,Kudling TV,Girych M,Haybout L,Pakola S,Hamdan F,Cervera-Carrascon V,Hemmes A,Grönberg-Vähä-Koskela S,Santos JM,Quixabeira DCA,Basnet S,Heiniö C,Arias V,Jirovec E,Kaptan S,Havunen R,Sorsa S,Erikat A,Schwartz J,Anttila M,Aro K,Viitala T,Vattulainen I,Cerullo V,Kanerva A,Hemminki A
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Feb 27 00:00:00 EST 2023
Anti-tumor memory CD4 and CD8 T-cells quantified by bulk T-cell receptor (TCR) clonal analysis.
Frontiers in immunology
Gao Y,Bergman I
47-0041-82 was used in Flow cytometry/Cell sorting to show that this methodology can be developed to use blood and tissue sampling to rapidly quantify the effectiveness of a tumor vaccine or any vaccine generating therapeutic T-cells.
Tue Apr 11 00:00:00 EDT 2023
GH18 family glycoside hydrolase Chitinase A of Salmonella enhances virulence by facilitating invasion and modulating host immune responses.
PLoS pathogens
Chandra K,Roy Chowdhury A,Chatterjee R,Chakravortty D
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2022
Rotenone aggravates PD-like pathology in A53T mutant human α-synuclein transgenic mice in an age-dependent manner.
Frontiers in aging neuroscience
Chen AD,Cao JX,Chen HC,Du HL,Xi XX,Sun J,Yin J,Jing YH,Gao LP
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Aug 26 00:00:00 EDT 2022
IL-33 Deficiency Attenuates Lung Inflammation by Inducing Th17 Response and Impacting the Th17/Treg Balance in LPS-Induced ARDS Mice via Dendritic Cells.
Journal of immunology research
Cheng L,Jiao Y,Jiang W,Zhang X,Zhang L,Jia G
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Dec 27 00:00:00 EST 2022
Interferon-γ Stimulates Interleukin-27 Derived from Dendritic Cells to Regulate Th9 Differentiation through STAT1/3 Pathway.
Disease markers
Xiong P,Liu T,Chen Y,Xu Q,Hu X,Han F,Shi L
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Oct 31 00:00:00 EDT 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Free Fatty Acid Receptor 4 (FFA4) Activation Ameliorates Imiquimod-Induced Psoriasis in Mice.
International journal of molecular sciences
Son SE,Koh JM,Im DS
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells.
Frontiers in cardiovascular medicine
Nettersheim FS,Ghosheh Y,Winkels H,Kobiyama K,Durant C,Armstrong SS,Brunel S,Roy P,Dileepan T,Jenkins MK,Zajonc DM,Ley K
47-0041-82 was used in Flow cytometry/Cell sorting to determine the specificity of this TCR to P6.
Wed Jan 03 00:00:00 EST 2024
Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide.
International journal of molecular sciences
Pauwels E,Provinciael B,Camps A,Hartmann E,Vermeire K
47-0041-82 was used in Flow Cytometry to study the impact of altered DNAJC3 protein levels on the inhibitory activity of cyclotriazadisulfonamide.
Thu Jan 06 00:00:00 EST 2022
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis.
Immunity
Almeida L,Dhillon-LaBrooy A,Castro CN,Adossa N,Carriche GM,Guderian M,Lippens S,Dennerlein S,Hesse C,Lambrecht BN,Berod L,Schauser L,Blazar BR,Kalesse M,Müller R,Moita LF,Sparwasser T
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade.
Cancer cell
Srivastava S,Furlan SN,Jaeger-Ruckstuhl CA,Sarvothama M,Berger C,Smythe KS,Garrison SM,Specht JM,Lee SM,Amezquita RA,Voillet V,Muhunthan V,Yechan-Gunja S,Pillai SPS,Rader C,Houghton AM,Pierce RH,Gottardo R,Maloney DG,Riddell SR
47-0041-82 was used in Flow Cytometry to test strategies for enhancing efficacy of CAR-T cells targeting the tumor-associated antigen receptor tyrosine kinase-like orphan receptor 1 (ROR1) infiltrating tumors.
Mon Feb 08 00:00:00 EST 2021
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Nature immunology
Gu M,Zhou X,Sohn JH,Zhu L,Jie Z,Yang JY,Zheng X,Xie X,Yang J,Shi Y,Brightbill HD,Kim JB,Wang J,Cheng X,Sun SC
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase.
International journal of oral science
Zhao X,Liu J,Zhang C,Yu N,Lu Z,Zhang S,Li Y,Li Q,Liu J,Liu D,Pan Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.
The Journal of experimental medicine
Sasai M,Ma JS,Okamoto M,Nishino K,Nagaoka H,Takashima E,Pradipta A,Lee Y,Kosako H,Suh PG,Yamamoto M
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
High Ambient Temperature Aggravates Experimental Autoimmune Uveitis Symptoms.
Frontiers in cell and developmental biology
Pan S,Tan H,Chang R,Wang Q,Zhu Y,Chen L,Li H,Su G,Zhou C,Cao Q,Kijlstra A,Yang P
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Dynamic changes in the systemic immune responses of spinal cord injury model mice.
Neural regeneration research
Gao TY,Huang FF,Xie YY,Wang WQ,Wang LD,Mu D,Cui Y,Wang B
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Generation of a Novel Oncolytic Vaccinia Virus Using the IHD-W Strain.
Human gene therapy
Shin J,Hong SO,Kim M,Lee H,Choi H,Kim J,Hong J,Kang H,Lee E,Lee S,Kong B,Kim M,Choi H,Kim S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
CXCR3 alleviates renal ischemia‑reperfusion injury via increase of Tregs.
Molecular medicine reports
Xian W,Wu J,Li Q,Du X,Wang N,Chen D,Gao W,Cao J
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia-induced brain injury in Wistar-Kyoto rats.
Experimental and therapeutic medicine
Zhang Y,Wang L,Li X,Geng J
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Estrogen receptor beta signaling in CD8+ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch.
Journal for immunotherapy of cancer
Yuan B,Clark CA,Wu B,Yang J,Drerup JM,Li T,Jin VX,Hu Y,Curiel TJ,Li R
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
A lymph node-targeted Amphiphile vaccine induces potent cellular and humoral immunity to SARS-CoV-2.
Science advances
Steinbuck MP,Seenappa LM,Jakubowski A,McNeil LK,Haqq CM,DeMuth PC
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation.
Frontiers in immunology
Amobi-McCloud A,Muthuswamy R,Battaglia S,Yu H,Liu T,Wang J,Putluri V,Singh PK,Qian F,Huang RY,Putluri N,Tsuji T,Lugade AA,Liu S,Odunsi K
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Oct 29 00:00:00 EDT 2021
Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells.
Stem cell research & therapy
Liu W,Zhou N,Liu Y,Zhang W,Li X,Wang Y,Zheng R,Zhang Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Feb 26 00:00:00 EST 2021
G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence.
Cell death & disease
Sun SN,Ni SH,Li Y,Liu X,Deng JP,Chen ZX,Li H,Feng WJ,Huang YS,Li DN,Xian SX,Yang ZQ,Wang LJ,Lu L
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Butyrate Improves Skin/Lung Fibrosis and Intestinal Dysbiosis in Bleomycin-Induced Mouse Models.
International journal of molecular sciences
Park HJ,Jeong OY,Chun SH,Cheon YH,Kim M,Kim S,Lee SI
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Mar 09 00:00:00 EST 2021
Mapping Rora expression in resting and activated CD4+ T cells.
PloS one
Haim-Vilmovsky L,Henriksson J,Walker JA,Miao Z,Natan E,Kar G,Clare S,Barlow JL,Charidemou E,Mamanova L,Chen X,Proserpio V,Pramanik J,Woodhouse S,Protasio AV,Efremova M,Griffin JL,Berriman M,Dougan G,Fisher J,Marioni JC,McKenzie ANJ,Teichmann SA
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid.
The Journal of biological chemistry
Zhao Y,Cheng R,Zhao Y,Ge W,Yang Y,Ding Z,Xu X,Wang Z,Wu Z,Zhang J
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Oct 07 00:00:00 EDT 2021
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Oxygen-Enriched Metal-Phenolic X-Ray Nanoprocessor for Cancer Radio-Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sang W,Xie L,Wang G,Li J,Zhang Z,Li B,Guo S,Deng CX,Dai Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Systemic Delivery of Oncolytic Adenovirus to Tumors Using Tumor-Infiltrating Lymphocytes as Carriers.
Cells
Santos J,Heiniö C,Quixabeira D,Zafar S,Clubb J,Pakola S,Cervera-Carrascon V,Havunen R,Kanerva A,Hemminki A
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Apr 22 00:00:00 EDT 2021
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota.
Theranostics
Tong L,Hao H,Zhang Z,Lv Y,Liang X,Liu Q,Liu T,Gong P,Zhang L,Cao F,Pastorin G,Lee CN,Chen X,Wang JW,Yi H
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Jan 28 00:00:00 EST 2022
Inducible T-Cell Costimulator Mediates Lymphocyte/Macrophage Interactions During Liver Repair.
Frontiers in immunology
Ramavath NN,Gadipudi LL,Provera A,Gigliotti LC,Boggio E,Bozzola C,Albano E,Dianzani U,Sutti S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Feb 14 00:00:00 EST 2022
Remote Limb Ischemic Postconditioning Protects Against Ischemic Stroke by Promoting Regulatory T Cells Thriving.
Journal of the American Heart Association
Yu HH,Ma XT,Ma X,Chen M,Chu YH,Wu LJ,Wang W,Qin C,Tian DS
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Nov 16 00:00:00 EST 2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Journal for immunotherapy of cancer
Wang Z,Xu F,Hu J,Zhang H,Cui L,Lu W,He W,Wang X,Li M,Zhang H,Xiong W,Xie C,Liu Y,Zhou P,Liu J,Huang P,Qin XF,Xia X
47-0041-82 was used in Flow Cytometry to show that clotrimazole could trigger DC activation via the lactate-lysosome axis to promote antigen cross-presentation and could be used as a potential combination therapy approach to improving the therapeutic efficacy of anti-PD1 immunotherapy.
Sat May 01 00:00:00 EDT 2021
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
47-0041-82 was used in Flow Cytometry to show that IL-22, a cytokine produced by RORγt+ lymphocytes inhibits IL-13-induced tuft cell differentiation in vitro, and suppresses the tuft cell-type 2 immune circuit and small intestine lengthening in vivo, highlighting its key role in gut tissue remodeling.
Thu Jul 22 00:00:00 EDT 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
Bonavita E,Bromley CP,Jonsson G,Pelly VS,Sahoo S,Walwyn-Brown K,Mensurado S,Moeini A,Flanagan E,Bell CR,Chiang SC,Chikkanna-Gowda CP,Rogers N,Silva-Santos B,Jaillon S,Mantovani A,Reis e Sousa C,Guerra N,Davis DM,Zelenay S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2020
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
Bonavita E,Bromley CP,Jonsson G,Pelly VS,Sahoo S,Walwyn-Brown K,Mensurado S,Moeini A,Flanagan E,Bell CR,Chiang SC,Chikkanna-Gowda CP,Rogers N,Silva-Santos B,Jaillon S,Mantovani A,Reis e Sousa C,Guerra N,Davis DM,Zelenay S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2020
Splenic Capture and In Vivo Intracellular Biodegradation of Biological-Grade Graphene Oxide Sheets.
ACS nano
Newman L,Jasim DA,Prestat E,Lozano N,de Lazaro I,Nam Y,Assas BM,Pennock J,Haigh SJ,Bussy C,Kostarelos K
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Aug 25 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells.
PLoS pathogens
Akhtar MN,Mishra M,Yadav V,Yadav M,Gujar R,Lal S,Kumar R,Khatri N,Sen P
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells.
Journal of cellular and molecular medicine
Wu R,Liu C,Deng X,Chen L,Hao S,Ma L
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma.
Journal of cellular and molecular medicine
Song Y,Wang Z,Jiang J,Piao Y,Li L,Xu C,Piao H,Li L,Yan G
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Effects of combined treatment with PD‑L1 Ig and CD40L mAb on immune tolerance in the CBA/J x DBA/2 mouse model.
Molecular medicine reports
Li G,Yang L,Li D,Zhang J,Du L,Xia L,Liu Y,Hu W
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress.
Cell death & disease
Kim KW,Ryu JS,Ko JH,Kim JY,Kim HJ,Lee HJ,Oh JH,Chung JH,Oh JY
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
Elevated granulocytic myeloid-derived suppressor cells are closely related with elevation of Th17 cells in mice with experimental asthma.
International journal of biological sciences
Xue F,Yu M,Li L,Zhang W,Ma Y,Dong L,Shan W,Zheng Y,Wang T,Feng D,Lv J,Wang X
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.
International journal of molecular sciences
Yoon CH,Ryu JS,Hwang HS,Kim MK
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Jun 11 00:00:00 EDT 2020
Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma.
Cells
Martinikova AS,Burocziova M,Stoyanov M,Macurek L
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Sep 10 00:00:00 EDT 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Communications biology
Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S
47-0041 was used in Flow cytometry/Cell sorting to show that a specific small-molecule tankyrase inhibitor, G007-LK, decreases WNT/β-catenin and YAP signaling in the syngeneic murine B16-F10 and Clone M-3 melanoma models and sensitizes the tumors to anti-PD-1 immune checkpoint therapy.
Fri Apr 24 00:00:00 EDT 2020
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Communications biology
Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S
47-0041 was used in Flow cytometry/Cell sorting to show that a specific small-molecule tankyrase inhibitor, G007-LK, decreases WNT/β-catenin and YAP signaling in the syngeneic murine B16-F10 and Clone M-3 melanoma models and sensitizes the tumors to anti-PD-1 immune checkpoint therapy.
Fri Apr 24 00:00:00 EDT 2020
CD4+ T Cells Cross-Reactive with Dengue and Zika Viruses Protect against Zika Virus Infection.
Cell reports
Wen J,Wang YT,Valentine KM,Dos Santos Alves RP,Xu Z,Regla-Nava JA,Ngono AE,Young MP,Ferreira LCS,Shresta S
47-0041 was used in Flow cytometry/Cell sorting to examine the ability of DENV/ZIKV-cross-reactive CD4+ T cells to protect against versus exacerbate ZIKV infection.
Tue Apr 28 00:00:00 EDT 2020
The Proteomic Landscape of Resting and Activated CD4+ T Cells Reveal Insights into Cell Differentiation and Function.
International journal of molecular sciences
Subbannayya Y,Haug M,Pinto SM,Mohanty V,Meås HZ,Flo TH,Prasad TSK,Kandasamy RK
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2020
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
PloS one
Hanson A,Elpek K,Duong E,Shallberg L,Fan M,Johnson C,Wallace M,Mabry GR,Sazinsky S,Pepper L,Shu CJ,Sathyanarayanan S,Zuerndorfer S,Simpson T,Gostissa M,Briskin M,Law D,Michaelson J,Harvey CJ
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2020
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
PloS one
Hanson A,Elpek K,Duong E,Shallberg L,Fan M,Johnson C,Wallace M,Mabry GR,Sazinsky S,Pepper L,Shu CJ,Sathyanarayanan S,Zuerndorfer S,Simpson T,Gostissa M,Briskin M,Law D,Michaelson J,Harvey CJ
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2020
GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation.
Cell reports
Castro-Dopico T,Fleming A,Dennison TW,Ferdinand JR,Harcourt K,Stewart BJ,Cader Z,Tuong ZK,Jing C,Lok LSC,Mathews RJ,Portet A,Kaser A,Clare S,Clatworthy MR
47-0041 was used in Flow cytometry/Cell sorting to identify granulocyte-macrophage colony stimulating factor (GM-CSF) as a critical regulator of intestinal macrophage activation in patients with IBD and mice with dextran sodium sulfate (DSS)-induced colitis.
Tue Jul 07 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Frontiers in immunology
Yu Y,Wu DM,Li J,Deng SH,Liu T,Zhang T,He M,Zhao YY,Xu Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.
Nature
Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
The cis-Regulatory Atlas of the Mouse Immune System.
Cell
Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C
47-0041-82 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.
Thu Feb 07 00:00:00 EST 2019
Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States.
Immunity
Wei SC,Sharma R,Anang NAS,Levine JH,Zhao Y,Mancuso JJ,Setty M,Sharma P,Wang J,Pe'er D,Allison JP
47-0041 was used in Flow cytometry/Cell sorting to implicate negative co-stimulation as a key regulator and determinant of T cell differentiation and suggest that checkpoint blockade might work in part by altering the limits of T cell phenotypes.
Tue Apr 16 00:00:00 EDT 2019
Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria.
Cell host & microbe
Leech JM,Dhariwala MO,Lowe MM,Chu K,Merana GR,Cornuot C,Weckel A,Ma JM,Leitner EG,Gonzalez JR,Vasquez KS,Diep BA,Scharschmidt TC
47-0041-82 was used in Flow cytometry/Cell sorting to study how skin colonization by commensal Staphylococcus epidermidis facilitates immune tolerance preferentially in neonates via induction of antigen-specific regulatory T cells.
Wed Dec 11 00:00:00 EST 2019
Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria.
Cell host & microbe
Leech JM,Dhariwala MO,Lowe MM,Chu K,Merana GR,Cornuot C,Weckel A,Ma JM,Leitner EG,Gonzalez JR,Vasquez KS,Diep BA,Scharschmidt TC
47-0041-82 was used in Flow cytometry/Cell sorting to study how skin colonization by commensal Staphylococcus epidermidis facilitates immune tolerance preferentially in neonates via induction of antigen-specific regulatory T cells.
Wed Dec 11 00:00:00 EST 2019
Post-transplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression.
The Journal of clinical investigation
Wachsmuth LP,Patterson MT,Eckhaus MA,Venzon DJ,Gress RE,Kanakry CG
47-0041-82 was used in Flow Cytometry to prompt a paradigm-shift in our mechanistic understanding of PTCy.
Tue Mar 26 00:00:00 EDT 2019
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
47-0041 was used in Flow cytometry/Cell sorting to show that teniposide could trigger tumor immunogenicity and enable a potential chemoimmunotherapeutic approach to potentiating the therapeutic efficacy of anti-PD1 immunotherapy.
Tue Aug 13 00:00:00 EDT 2019
Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Birkl D,O'Leary MN,Quiros M,Azcutia V,Schaller M,Reed M,Nishio H,Keeney J,Neish AS,Lukacs NW,Parkos CA,Nusrat A
47-0041-82 was used in Flow Cytometry to study how Fpr2/3 regulates CCL20-CCR6-mediated monocyte chemotaxis to sites of mucosal injury in the gut to influence wound repair.
Sun Dec 01 00:00:00 EST 2019
Characterization of immune cell subtypes in three commonly used mouse strains reveals gender and strain-specific variations.
Laboratory investigation; a journal of technical methods and pathology
Hensel JA,Khattar V,Ashton R,Ponnazhagan S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
Bryostatin-1 ameliorated experimental colitis in Il-10-/- Mice by protecting the intestinal barrier and limiting immune dysfunction.
Journal of cellular and molecular medicine
Zuo L,Li J,Ge S,Ge Y,Shen M,Wang Y,Zhou C,Wu R,Hu J
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2019
Lactobacillus rhamnosus GG attenuates tenofovir disoproxil fumarate-induced bone loss in male mice via gut-microbiota-dependent anti-inflammation.
Therapeutic advances in chronic disease
Liu H,Gu R,Li W,Zhou W,Cong Z,Xue J,Liu Y,Wei Q,Zhou Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sat Apr 09 00:00:00 EDT 2022
Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway.
Mediators of inflammation
Xu Y,Tang X,Yang M,Zhang S,Li S,Chen Y,Liu M,Guo Y,Lu M
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model.
Biology open
Huang J,Yue H,Jiang T,Gao J,Shi Y,Shi B,Wu X,Gou X
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jan 15 00:00:00 EST 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses.
NPJ vaccines
Li G,Adam A,Luo H,Shan C,Cao Z,Fontes-Garfias CR,Sarathy VV,Teleki C,Winkelmann ER,Liang Y,Sun J,Bourne N,Barrett ADT,Shi PY,Wang T
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Next Generation Sequencing for Long Non-coding RNAs Profile for CD4+ T Cells in the Mouse Model of Acute Asthma.
Frontiers in genetics
Wang Z,Ji N,Chen Z,Wu C,Sun Z,Yu W,Hu F,Huang M,Zhang M
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
47-0041 was used in Flow cytometry/Cell sorting to investigate the underlying sex differences that may contribute to differential footpad delayed-type hypersensitivity responses using wildtype and four core genotypes mice and popliteal lymphnode cellularity and gene expression.
Wed Jan 30 00:00:00 EST 2019
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
47-0041 was used in Flow cytometry/Cell sorting to investigate the underlying sex differences that may contribute to differential footpad delayed-type hypersensitivity responses using wildtype and four core genotypes mice and popliteal lymphnode cellularity and gene expression.
Wed Jan 30 00:00:00 EST 2019
TLR1/2 Specific Small-Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cen X,Zhu G,Yang J,Yang J,Guo J,Jin J,Nandakumar KS,Yang W,Yin H,Liu S,Cheng K
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri May 17 00:00:00 EDT 2019
Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.
Cell reports
Cianciaruso C,Beltraminelli T,Duval F,Nassiri S,Hamelin R,Mozes A,Gallart-Ayala H,Ceada Torres G,Torchia B,Ries CH,Ivanisevic J,De Palma M
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Duration of Humoral and Cellular Immunity 8 Years After Administration of Reduced Doses of the 17DD-Yellow Fever Vaccine.
Frontiers in immunology
da Costa-Rocha IA,Campi-Azevedo AC,Peruhype-Magalhães V,Coelho-Dos-Reis JG,Fradico JRB,Souza-Lopes T,Reis LR,Freire LC,Costa-Pereira C,Mambrini JVM,Maia MLS,de Lima SMB,de Noronha TG,Xavier JR,Camacho LAB,de Albuquerque EM,Farias RHG,de Castro TDM,Homma A,Romano APM,Domingues CM,Martins RM,Teixeira-Carvalho A,Martins-Filho OA
47-0041-82 was used in In vitro Assay to support the regular use of dose sparing strategy for YF vaccine in adults.
Mon Oct 19 00:00:00 EDT 2020
Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells.
Immunity
Halim TYF,Rana BMJ,Walker JA,Kerscher B,Knolle MD,Jolin HE,Serrao EM,Haim-Vilmovsky L,Teichmann SA,Rodewald HR,Botto M,Vyse TJ,Fallon PG,Li Z,Withers DR,McKenzie ANJ
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy.
The Journal of clinical investigation
Zamarin D,Ricca JM,Sadekova S,Oseledchyk A,Yu Y,Blumenschein WM,Wong J,Gigoux M,Merghoub T,Wolchok JD
47-0041 was used in Flow cytometry/Cell sorting to use human tumour histocultures and syngeneic tumour models treated with Newcastle disease virus to identify immune targets upregulated by OV treatment.
Mon Apr 02 00:00:00 EDT 2018
Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.
The Journal of clinical investigation
Emmerson A,Trevelin SC,Mongue-Din H,Becker PD,Ortiz C,Smyth LA,Peng Q,Elgueta R,Sawyer G,Ivetic A,Lechler RI,Lombardi G,Shah AM
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Jul 02 00:00:00 EDT 2018
Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy.
Molecular therapy : the journal of the American Society of Gene Therapy
Ricca JM,Oseledchyk A,Walther T,Liu C,Mangarin L,Merghoub T,Wolchok JD,Zamarin D
47-0041 was used in Flow cytometry/Cell sorting to study the effects of pre-existing anti-viral immunity on therapeutic efficacy in syngeneic mouse tumour models.
Wed Apr 04 00:00:00 EDT 2018
Prophylactic vs. Therapeutic Treatment With P2Et Polyphenol-Rich Extract Has Opposite Effects on Tumor Growth.
Frontiers in oncology
Lasso P,Gomez-Cadena A,Urueña C,Donda A,Martinez-Usatorre A,Barreto A,Romero P,Fiorentino S
47-0041 was used in Flow cytometry/Cell sorting to evaluate the ability of P2Et extract to modulate the immune system in both steady state and tumour challenge.
Thu Oct 01 00:00:00 EDT 2020
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells.
World journal of gastroenterology
Müller-Graff FT,Fitzner B,Jaster R,Vollmar B,Zechner D
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sat Jul 28 00:00:00 EDT 2018
Early-life antibiotics attenuate regulatory T cell generation and increase the severity of murine house dust mite-induced asthma.
Pediatric research
Adami AJ,Bracken SJ,Guernsey LA,Rafti E,Maas KR,Graf J,Matson AP,Thrall RS,Schramm CM
47-0041 was used in Flow cytometry/Cell sorting to suggest targets for immunologic or probiotic therapy to counteract the harmful effects of childhood ABX.
Sat Sep 01 00:00:00 EDT 2018
Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis.
Evidence-based complementary and alternative medicine : eCAM
Pang P,Zheng K,Wu S,Xu H,Deng L,Shi Y,Chen X
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival.
JCI insight
McCall CE,Zabalawi M,Liu T,Martin A,Long DL,Buechler NL,Arts RJW,Netea M,Yoza BK,Stacpoole PW,Vachharajani V
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Aug 09 00:00:00 EDT 2018
Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation.
eLife
Lian G,Gnanaprakasam JR,Wang T,Wu R,Chen X,Liu L,Shen Y,Yang M,Yang J,Chen Y,Vasiliou V,Cassel TA,Green DR,Liu Y,Fan TW,Wang R
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Sep 10 00:00:00 EDT 2018
A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.
Nature communications
Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Apr 18 00:00:00 EDT 2018
Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Peng J,Xiao Y,Li W,Yang Q,Tan L,Jia Y,Qu Y,Qian Z
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells.
Nature communications
Straub T,Freudenberg MA,Schleicher U,Bogdan C,Gasteiger G,Pircher H
47-0041 was used in Flow cytometry/Cell sorting to suggest a TLR4-mediated immunoregulatory role of NK cells during viral-bacterial coinfections.
Mon Oct 08 00:00:00 EDT 2018
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.
Journal of neuroinflammation
Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Sep 21 00:00:00 EDT 2018
Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling.
Nature communications
Piao W,Xiong Y,Famulski K,Brinkman CC,Li L,Toney N,Wagner C,Saxena V,Simon T,Bromberg JS
47-0041 was used in Flow cytometry/Cell sorting to demonstrate the importance of LTΒR signaling in leukocyte migration and LEC and lymphatic vessel function, and show that antagonist peptides may serve as lead compounds for therapeutic applications.
Wed Aug 01 00:00:00 EDT 2018
IL-7 treatment augments and prolongs sepsis-induced expansion of IL-10-producing B lymphocytes and myeloid-derived suppressor cells.
PloS one
Kulkarni U,Herrmenau C,Win SJ,Bauer M,Kamradt T
47-0041 was used in Flow cytometry/Cell sorting to investigate the expansion of immunoregulatory cells as long-term sequelae of sepsis with or without IL-7 treatment.
Mon Apr 09 00:00:00 EDT 2018
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.
Frontiers in physiology
Lim D,Kim W,Lee C,Bae H,Kim J
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Plasmodium co-infection protects against chikungunya virus-induced pathologies.
Nature communications
Teo TH,Lum FM,Ghaffar K,Chan YH,Amrun SN,Tan JJL,Lee CYP,Chua TK,Carissimo G,Lee WWL,Claser C,Rajarethinam R,Rénia L,Ng LFP
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Sep 25 00:00:00 EDT 2018
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Journal of experimental & clinical cancer research : CR
Xu L,Zhang Y,Tian K,Chen X,Zhang R,Mu X,Wu Y,Wang D,Wang S,Liu F,Wang T,Zhang J,Liu S,Zhang Y,Tu C,Liu H
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Oct 29 00:00:00 EDT 2018
Multi-parameter approach to evaluate the timing of memory status after 17DD-YF primary vaccination.
PLoS neglected tropical diseases
Costa-Pereira C,Campi-Azevedo AC,Coelho-Dos-Reis JG,Peruhype-Magalhães V,Araújo MSS,do Vale Antonelli LR,Fonseca CT,Lemos JA,Malaquias LCC,de Souza Gomes M,Rodrigues Amaral L,Rios M,Chancey C,Persi HR,Pereira JM,de Sousa Maia ML,Freire MDS,Martins RM,Homma A,Simões M,Yamamura AY,Farias RHG,Romano APM,Domingues CM,Tauil PL,Vasconcelos PFC,Caldas IR,Camacho LA,Teixeira-Carvalho A,Martins-Filho OA
47-0041 was used in Flow cytometry/Cell sorting to identify a minimum set of phenotypic/functional memory-related biomarkers for post-vaccination follow-up upon yellow fever vaccination.
Fri Jun 01 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Limited Foxp3+ Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8+ T Cell Immunity.
Frontiers in immunology
Araujo Furlan CL,Tosello Boari J,Rodriguez C,Canale FP,Fiocca Vernengo F,Boccardo S,Beccaria CG,Adoue V,Joffre O,Gruppi A,Montes CL,Acosta Rodriguez EV
47-0041 was used in Flow cytometry/Cell sorting to study the role of regulatory T cells during Trypanosoma cruzi infection.
Thu Sep 26 00:00:00 EDT 2019
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Nature medicine
Giles DA,Moreno-Fernandez ME,Stankiewicz TE,Graspeuntner S,Cappelletti M,Wu D,Mukherjee R,Chan CC,Lawson MJ,Klarquist J,Sünderhauf A,Softic S,Kahn CR,Stemmer K,Iwakura Y,Aronow BJ,Karns R,Steinbrecher KA,Karp CL,Sheridan R,Shanmukhappa SK,Reynaud D,Haslam DB,Sina C,Rupp J,Hogan SP,Divanovic S
47-0041 was used in Flow cytometry/Cell sorting to show thermoneutral housing provides a sex-independent model of exacerbated NAFLD in mice and represents a novel approach for interrogation of the cellular and molecular mechanisms underlying disease pathogenesis.
Sat Jul 01 00:00:00 EDT 2017
Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.
Immunity
Vaeth M,Maus M,Klein-Hessling S,Freinkman E,Yang J,Eckstein M,Cameron S,Turvey SE,Serfling E,Berberich-Siebelt F,Possemato R,Feske S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy.
Brain : a journal of neurology
Laurent C,Dorothée G,Hunot S,Martin E,Monnet Y,Duchamp M,Dong Y,Légeron FP,Leboucher A,Burnouf S,Faivre E,Carvalho K,Caillierez R,Zommer N,Demeyer D,Jouy N,Sazdovitch V,Schraen-Maschke S,Delarasse C,Buée L,Blum D
47-0041 was used in Flow cytometry/Cell sorting to elucidate the contribution of brain immune cells in tau-driven pathophysiology in Alzheimer's.
Sun Jan 01 00:00:00 EST 2017
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sat Jul 15 00:00:00 EDT 2017
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Pishesha N,Bilate AM,Wibowo MC,Huang NJ,Li Z,Deshycka R,Bousbaine D,Li H,Patterson HC,Dougan SK,Maruyama T,Lodish HF,Ploegh HL
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Mar 21 00:00:00 EDT 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Role of Prolactin in Promotion of Immune Cell Migration into the Mammary Gland.
Journal of mammary gland biology and neoplasia
Dill R,Walker AM
47-0041 was used in Flow cytometry/Cell sorting to investigate the role of prolactin in immune cell recruitment.
Wed Mar 01 00:00:00 EST 2017
Location of tumor affects local and distant immune cell type and number.
Immunity, inflammation and disease
Hensel JA,Khattar V,Ashton R,Lee C,Siegal GP,Ponnazhagan S
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.
Stem cell research & therapy
Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Nov 10 00:00:00 EST 2017
Evaluation of Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites as a Preerythrocytic P. vivax Vaccine.
Clinical and vaccine immunology : CVI
Alves E,Salman AM,Leoratti F,Lopez-Camacho C,Viveros-Sandoval ME,Lall A,El-Turabi A,Bachmann MF,Hill AV,Janse CJ,Khan SM,Reyes-Sandoval A
47-0041 was used in Flow cytometry/Cell sorting to generate vaccine platforms targeting a malarial parasite protein and assess them for protective efficacy.
Sat Apr 01 00:00:00 EDT 2017
MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis.
Stem cell reports
Shigemoto-Kuroda T,Oh JY,Kim DK,Jeong HJ,Park SY,Lee HJ,Park JW,Kim TW,An SY,Prockop DJ,Lee RH
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue May 09 00:00:00 EDT 2017
Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells.
Frontiers in pharmacology
Li M,Gao J,Tang Y,Liu M,Wu S,Qu K,Long X,Li H,Liu M,Liu Y,Yuan J,Mao L,Liu Y,Zheng X,Wang E,Wang J,Yang Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
PloS one
Min M,Yan BX,Wang P,Landeck L,Chen JQ,Li W,Cai SQ,Zheng M,Man XY
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment.
Journal for immunotherapy of cancer
Poon E,Mullins S,Watkins A,Williams GS,Koopmann JO,Di Genova G,Cumberbatch M,Veldman-Jones M,Grosskurth SE,Sah V,Schuller A,Reimer C,Dovedi SJ,Smith PD,Stewart R,Wilkinson RW
47-0041 was used in Flow cytometry/Cell sorting to characterise the combined effects of MEK inhibition and anti-CTLA-4 monoclonal antibody therapy, examining effects on both T-cells and tumour microenvironment.
Tue Aug 15 00:00:00 EDT 2017
Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer.
Oncoimmunology
Huang RY,Francois A,McGray AR,Miliotto A,Odunsi K
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation.
EBioMedicine
Ma J,Teng X,Wang X,Fan X,Wu Y,Tian M,Zhou Z,Li L
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Oct 06 00:00:00 EDT 2016
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
Nature immunology
Gerriets VA,Kishton RJ,Johnson MO,Cohen S,Siska PJ,Nichols AG,Warmoes MO,de Cubas AA,MacIver NJ,Locasale JW,Turka LA,Wells AD,Rathmell JC
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
47-0041 was used in Flow cytometry/Cell sorting to identify a novel pathway of cross-talk between macrophages and dendritic cells.
Sat Oct 01 00:00:00 EDT 2016
p(⁷⁰S⁶K¹) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
European journal of immunology
Sasaki CY,Chen G,Munk R,Eitan E,Martindale J,Longo DL,Ghosh P
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Mon Aug 15 00:00:00 EDT 2016
Protein Translation Activity: A New Measure of Host Immune Cell Activation.
Journal of immunology (Baltimore, Md. : 1950)
Seedhom MO,Hickman HD,Wei J,David A,Yewdell JW
47-0041 was used in Flow cytometry/Cell sorting to describe the in vivo ribopuromycylation method.
Mon Aug 15 00:00:00 EDT 2016
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Molecular medicine reports
Gu L,Deng WS,Sun XF,Zhou H,Xu Q
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sun May 15 00:00:00 EDT 2016
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration.
Nature communications
Brinkman CC,Iwami D,Hritzo MK,Xiong Y,Ahmad S,Simon T,Hippen KL,Blazar BR,Bromberg JS
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jun 21 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis.
PloS one
Giles DA,Moreno-Fernandez ME,Stankiewicz TE,Cappelletti M,Huppert SS,Iwakura Y,Dong C,Shanmukhappa SK,Divanovic S
47-0041 was used in Flow cytometry/Cell sorting to indicate that the IL-17 axis also plays a role in a MCDD-induced model of NAFLD pathogenesis.
Tue Jul 19 00:00:00 EDT 2016
Interleukin-10 deficiency impairs regulatory T cell-derived neuropilin-1 functions and promotes Th1 and Th17 immunity.
Scientific reports
Wang S,Gao X,Shen G,Wang W,Li J,Zhao J,Wei YQ,Edwards CK
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2016
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells.
Nature communications
Alrefai H,Muhammad K,Rudolf R,Pham DA,Klein-Hessling S,Patra AK,Avots A,Bukur V,Sahin U,Tenzer S,Goebeler M,Kerstan A,Serfling E
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed May 25 00:00:00 EDT 2016
Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.
BMC complementary and alternative medicine
Zhang S,Liu X,Mei L,Wang H,Fang F
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Aug 31 00:00:00 EDT 2016
Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer.
Oncoimmunology
Lee SE,Hong SH,Verma V,Lee YS,Duong TN,Jeong K,Uthaman S,Sung YC,Lee JT,Park IK,Min JJ,Rhee JH
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.
Cell reports
Choi IY,Piccio L,Childress P,Bollman B,Ghosh A,Brandhorst S,Suarez J,Michalsen A,Cross AH,Morgan TE,Wei M,Paul F,Bock M,Longo VD
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jun 07 00:00:00 EDT 2016
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Cell reports
Schleicher U,Paduch K,Debus A,Obermeyer S,König T,Kling JC,Ribechini E,Dudziak D,Mougiakakos D,Murray PJ,Ostuni R,Körner H,Bogdan C
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Nature
Huang YH,Zhu C,Kondo Y,Anderson AC,Gandhi A,Russell A,Dougan SK,Petersen BS,Melum E,Pertel T,Clayton KL,Raab M,Chen Q,Beauchemin N,Yazaki PJ,Pyzik M,Ostrowski MA,Glickman JN,Rudd CE,Ploegh HL,Franke A,Petsko GA,Kuchroo VK,Blumberg RS
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Jan 15 00:00:00 EST 2015
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Phosphatase Wip1 controls antigen-independent B-cell development in a p53-dependent manner.
Blood
Yi W,Hu X,Chen Z,Liu L,Tian Y,Chen H,Cong YS,Yang F,Zhang L,Rudolph KL,Zhang Z,Zhao Y,Ju Z
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Jul 30 00:00:00 EDT 2015
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
The Journal of experimental medicine
Pallangyo CK,Ziegler PK,Greten FR
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Adaptive Immune Regulation of Mammary Postnatal Organogenesis.
Developmental cell
Plaks V,Boldajipour B,Linnemann JR,Nguyen NH,Kersten K,Wolf Y,Casbon AJ,Kong N,van den Bijgaart RJ,Sheppard D,Melton AC,Krummel MF,Werb Z
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Sep 14 00:00:00 EDT 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Mice lacking Axl and Mer tyrosine kinase receptors are susceptible to experimental autoimmune orchitis induction.
Immunology and cell biology
Li N,Liu Z,Zhang Y,Chen Q,Liu P,Cheng CY,Lee WM,Chen Y,Han D
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Histone deacetylation of memory T lymphocytes by You-Gui-Wan alleviates allergen-induced eosinophilic airway inflammation in asthma.
Chinese medicine
Zhang HP,Fu JJ,Fan T,Zhang WB,Wang ZL,Wang L,Wang G
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Jun 15 00:00:00 EDT 2015
Triclosan Induces Thymic Stromal Lymphopoietin in Skin Promoting Th2 Allergic Responses.
Toxicological sciences : an official journal of the Society of Toxicology
Marshall NB,Lukomska E,Long CM,Kashon ML,Sharpnack DD,Nayak AP,Anderson KL,Jean Meade B,Anderson SE
47-0041 was used in Flow cytometry/Cell sorting to examine the effects of dermal triclosan exposure on the skin and lymph nodes of mice and in a human skin model to identify mechanisms for augmenting allergic responses.
Tue Sep 01 00:00:00 EDT 2015
Mannan-modified adenovirus targeting TERT and VEGFR-2: A universal tumour vaccine.
Scientific reports
Wang Y,Zhang J,Wu Y,Ding ZY,Luo XM,Liu J,Zhong WN,Deng GH,Xia XY,Deng YT,Wei YQ,Jiang Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Jun 18 00:00:00 EDT 2015
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
Cell transplantation
Costa R,Bergwerf I,Santermans E,De Vocht N,Praet J,Daans J,Le Blon D,Hoornaert C,Reekmans K,Hens N,Goossens H,Berneman Z,Parolini O,Alviano F,Ponsaerts P
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2015
Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3.
PloS one
Deng YQ,Yang YQ,Wang SB,Li F,Liu MZ,Hua QQ,Tao ZZ
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue May 31 00:00:00 EDT 2016
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Sep 08 00:00:00 EDT 2015
Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
Autophagy
Dang S,Xu H,Xu C,Cai W,Li Q,Cheng Y,Jin M,Wang RX,Peng Y,Zhang Y,Wu C,He X,Wan B,Zhang Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
PLoS pathogens
Ataide MA,Andrade WA,Zamboni DS,Wang D,Souza Mdo C,Franklin BS,Elian S,Martins FS,Pereira D,Reed G,Fitzgerald KA,Golenbock DT,Gazzinelli RT
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
High-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protection.
European journal of immunology
Lindenstrøm T,Aagaard C,Christensen D,Agger EM,Andersen P
47-0041 was used in Flow cytometry/Cell sorting to study the role of CD8 T cells in resistance to mycobacterial infections.
Sun Jun 01 00:00:00 EDT 2014
Regulation of cyp26a1 on Th17 cells in mouse peri-implantation.
Journal of cellular and molecular medicine
Liu HY,Chao H,Liu ZK,Xia HF,Song Z,Yang Y,Peng JP
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Sat Mar 01 00:00:00 EST 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
High-dose interferon-γ promotes abortion in mice by suppressing Treg and Th17 polarization.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Liu HY,Liu ZK,Chao H,Li Z,Song Z,Yang Y,Peng JP
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects.
BMC cancer
Tian H,Shi G,Yang G,Zhang J,Li Y,Du T,Wang J,Xu F,Cheng L,Zhang X,Dai L,Chen X,Zhang S,Yang Y,Yu D,Wei Y,Deng H
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Jan 29 00:00:00 EST 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity.
Cell reports
Toso A,Revandkar A,Di Mitri D,Guccini I,Proietti M,Sarti M,Pinton S,Zhang J,Kalathur M,Civenni G,Jarrossay D,Montani E,Marini C,Garcia-Escudero R,Scanziani E,Grassi F,Pandolfi PP,Catapano CV,Alimonti A
47-0041 was used in Flow cytometry/Cell sorting to demonstrate that immune surveillance of senescent tumour cells can be suppressed in specific genetic backgrounds but also evoked by pharmacological treatments.
Thu Oct 09 00:00:00 EDT 2014
Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America
McKee AS,Burchill MA,Munks MW,Jin L,Kappler JW,Friedman RS,Jacobelli J,Marrack P
47-0041 was used in Flow cytometry/Cell sorting to study how aluminium acts as an adjuvant by introducing host DNA into the cytoplasm of dendritic cells, where it engages receptors promoting MHC II presentation.
Tue Mar 19 00:00:00 EDT 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Feb 01 00:00:00 EST 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
Enhanced immune response against HIV-1 induced by a heterologous DNA prime-adenovirus boost vaccination using mannosylated polyethyleneimine as DNA vaccine adjuvant.
International journal of nanomedicine
Li M,Jiang Y,Xu C,Zhang Z,Sun X
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Wed Apr 02 00:00:00 EDT 2014
Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis.
PloS one
Zanello G,Goethel A,Forster K,Geddes K,Philpott DJ,Croitoru K
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Jul 31 00:00:00 EDT 2014
The early activation marker CD69 regulates the expression of chemokines and CD4 T cell accumulation in intestine.
PloS one
Radulovic K,Rossini V,Manta C,Holzmann K,Kestler HA,Niess JH
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Jan 23 00:00:00 EST 2014
Requirement for diverse TCR specificities determines regulatory T cell activity in a mouse model of autoimmune arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Oh S,Aitken M,Simons DM,Basehoar A,Garcia V,Kropf E,Caton AJ
47-0041 was used in Flow cytometry/Cell sorting to investigate why CD4(+)CD25(+)Foxp3(+) Tregs allow organ-specific autoimmunity, showing that polyclonal Tregs suppressed Th17 cell formation and prevented arthritis development, but clonotypic Tregs did not, indicating that diverse TCR specificities are required.
Tue May 01 00:00:00 EDT 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950)
Wang R,Xie H,Huang Z,Ma J,Fang X,Ding Y,Sun Z
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2.
Investigative ophthalmology & visual science
Mochimaru H,Usui T,Yaguchi T,Nagahama Y,Hasegawa G,Usui Y,Shimmura S,Tsubota K,Amano S,Kawakami Y,Ishida S
Thu May 01 00:00:00 EDT 2008
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes.
Circulation
Yang Z,Day YJ,Toufektsian MC,Xu Y,Ramos SI,Marshall MA,French BA,Linden J
Tue Nov 07 00:00:00 EST 2006
Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis.
Proceedings of the National Academy of Sciences of the United States of America
Woolf E,Xiao C,Fainaru O,Lotem J,Rosen D,Negreanu V,Bernstein Y,Goldenberg D,Brenner O,Berke G,Levanon D,Groner Y
Published figure using CD4 monoclonal antibody (Product # 47-0041-82) in Flow Cytometry
Tue Jun 24 00:00:00 EDT 2003
