Transcend LX Multichannel UHPLC Systems
Improve your LC-MS throughput and get a faster return on investment with a Thermo Scientific Transcend Multichannel LX UHPLC Systems. These UHPLC systems features unique multichannel technology that uses up to four separate LC channels in combination with a single mass spectrometer to increase throughput. Transcend Multichannel LX UHPLC systems offer a new level of simplicity and cost-effectiveness. Thermo Scientific Aria MX software, featuring an intuitive graphical interface, makes method setup easy and schedules all aspects of the system, including scheduling and management for multiple methods on multiple channels, simultaneously.
Highlights
Increased mass spectrometer utilization
Transcend multichannel systems have two or four LC channels that operate in parallel, independently, into a single mass spectrometer to double or quadruple throughput. One method can be run on all channels or each channel can run a different method simultaneously.
Extended sample capacity
Sample capacity can be extended from six to twelve 96- or 384-well plates by adding another cool stack to the Thermo Scientific TriPlus RSI autosampler for greater throughput. Thermo Scientific Transcend VLX-2 offers increased sample capacity with the Thermo Scientific Vanquish Charger module for a total capacity of up to nearly 9000 samples while the barcode reader simultaneously manages the complete inventory.
Improved throughput
Multichannel technology increases throughput two- to four-fold using a single instrument with no need for new method development, accelerating laboratory output and revenue generation.
Easy setup and system control
Thermo Scientific Aria MX software manages and controls pump operation, valve switching, cleaning, and gradients. Quickly develop methods and run batches of samples while managing multiple LC-MS methods on multiple channels simultaneously. Aria MX software is compatible with Thermo Scientific XCalibur or TraceFinder software.
How does multichannel LC-MS work?
Our multichannel LC system is designed specifically for LC-MS and allows you to run two of the same or two different applications using one mass spectrometer. Two channels run staggered LC-MS analyses, ensuring the mass spectrometer is never idle. The diagram below illustrates the resulting MS signal when running two different applications on the Transcend Multichannel LX UHPLC system simultaneously.
Maximize MS utilization by using multiple channels with intelligent scheduling to run the second analysis during column reconditioning.
System specifications
The table below provides an overview of the Transcend Multichannel LX UHPLC systems specifications for a standard setup. Not all specifications are listed. Your specifications may differ based on the components of your system. Find the specification sheets for the system components in the Component specifications, below.
| Category | Transcend (F/H) VLX-2 UHPLC Systems | Transcend Multichannel LX-2 and LX-4 UHPLC Systems |
| System pressure, maximum | 1000 (F) or 1500 bar (H) | 1000 bar |
| Flow range | 0-8 mL/min (F) or 0-5 mL/min (H) | 0-8 mL/min |
| Pump options (default gradient delay volume) | Binary Pump F (35 µL) |
Binary (100 µL) |
| Biocompatible | Yes | |
| pH range | 2–12, chloride concentration up to 1 mol/L | |
| System design | Modular | |
| Touchscreen user interface display compatible (optional) | Yes, depends on system configuration | No |
| Solvent monitoring system compatible (optional) | No | |
| Customizable gradient delay volume to simplify method transfer | Not applicable | |
| SmartInject technology for maximum injection precision and improved column lifetime | Yes | No |
| Injection volume range | Standard: 0.01-25 µL Optional: 0.01-100 µL |
Standard: 0.01-100 µL Optional: up to 10,000 µL |
| Sample cooling | Yes | |
Sample capacity (standard) Based on standard 12 mm OD vials (≤ 1.5 mL) |
4 racks of 54 vials (≤ 1.5mL) each, |
6 racks that hold 54 vials each |
| Sampler extension available (optional) | Yes, with Vanquish Charger | Yes, with drawers |
| Column compartment thermostatting | Yes, 5-120°C Still air and forced air |
Yes Optional sleeve heater |
Column compartment pre-heater |
Active and passive |
n.a. |
| Column compartment post-column cooler | Yes | n.a. |
| Compatible Detectors | Mass Spectrometer |
|
Component specifications
Standard Transcend Multichannel LX UHPLC systems are made up of the following components. Download the associated specifications sheet for more detail on each component.
| Transcend LX-2 | Transcend LX-4 |
Transcend VLX-2 |
|
Pump
|
2 Vanquish Binary Pump F or 2 Vanquish Binary Pump H | ||
Autosampler
|
Triplus RSI | Vanquish Dual Split Sampler FT or Vanquish Dual Split Sampler HT | |
Extended sample capacity (optional)
|
3- or 6-drawer cool stack (optional) |
Vanquish Charger (optional) |
|
Flow path switching
|
2-valve interface module | Vanquish Column Compartment H | |
Detectors
|
One mass spectrometer | ||
For Research Use Only. Not for use in diagnostic procedures.