Cryo Electron Microscope | Cryo EM Funding and Grants

Research equipment grant writing and technical resources

Whether you are new to cryo-electron microscopy (cryo-EM) or have years of experience with this technology, securing funding can be demanding, time-consuming, and stressful. Our team is here to help!

This funding support center contains several resources, including:

Proposal writing tools
Potential funding opportunities
Available financial services
Technical content, data sheets, and guides

Cryo-EM grant proposal and funding resource center

Some common funding challenges include:

Identifying the right grant and determining eligibility
Finding the right collaborators
Getting preliminary data in time for submission; setting up demos with vendors
Writing and story telling
Obtaining short and long-term institutional support
Acquiring a copy of a similar, successful proposal

Our technical experts can support you every step of the way:

Helping you gather the right information to submit a well-supported and accurate application
Getting the preliminary data and rationale for your proposal
Providing information about financing and leasing solutions
Discussing ideal workflow solutions for your analytical needs
And much more

Cryo-electron microscopes

Find the right Thermo Scientific electron microscope for your research

Our dedicated customer success managers are your scientific partners. They can provide recommendations on the best instrumentation for your research as well as laboratory organization support, from sample preparation to electron microscopy and IT infrastructure. Explore our guidance for planning a cryo-EM laboratory for more information.


	Vitrobot System	Talos L120C TEM	Talos F200C TEM	Tundra Cryo-TEM	Glacios 2 Cryo-TEM	Krios G4 Cryo-TEM
Ideal Use or Applications	Sample prep Vitrification	Room temperature EM Pathology Cell biology Negative staining Limited Cryo-EM screening	Room temperature EM Pathology Cell biology Negative staining Limited cryo-EM screening Limited tomography	Sample optimization Biochemistry optimization Structure determination 100 kV single particle analysis (SPA)	Structure determination 200 kV SPA Cryo-tomography MicroED Energy filter compatible	Structure determination 300KV SPA Cryo-tomography MicroED Energy filter compatible Highest resolution
Key Benefits	Sample vitrification for optimal cryo-EM analysis	Ease-of-use, with multi-functional flexible applications	Ease-of-use, with multi-functional flexible applications	Cryo-EM within your reach: ease of use, with AI-guided automation	Routine, high- resolution SPA, with high throughput and productivity	Highest resolution SPA and tomography, with highest throughput and productivity
User Experience Level	All users	New users to experts	New users to experts	New to moderately experienced users	Moderately experienced to experts	Moderately experienced to experts
Cost to Get Started		$	$$	$	$$	$$$
Price Per Structure		N/A	N/A	$$$	$$	$
Product Datasheets	Vitrobot	Talos L120C	Talos F200C	Tundra Cryo-TEM	Glacios 2 Cryo-TEM	Krios G4 Cryo-TEM

Cryo-EM grant proposal and writing resources

Whether you are new to grant writing or have years of experience, securing funding can be demanding, time-consuming, and stressful. Not all funding opportunities are created equal, but successful grant applications have much in common. Watch our on-demand webinars for some proven grant writing strategies.

This on-demand webinar given by Dr. Christopher Dant discusses proven strategies used in the well-known Research (R01) grant application that can support your application for the NIH High-End Instrumentation (HEI) Grant Program (S10).

Watch an on-demand Q&A session about grant writing featuring Dr. Christopher Dant and Thermo Fisher Scientific Cryo-EM experts.

Winning the Shared Instrumentation S10 Grant from the National Institutes of Health

Grant Writing Journey Infographic

Potential funding opportunities for high-end instrumentation

Public and private grants are an ideal way to seek funding for the latest cryo-EM technology. This table presents some of the typical and lesser-known sources of funding.

Proposal Due Date	Grant Name	Division	Range
Periodic Basis	NIBIB P41 National Centers for Biomedical Imaging and Bioengineering	NIH	$500K - $750K
Ongoing Basis	Infrastructure Innovation for Biological Research (Innovation)	NSF	20 to 40 Awards in a pool of $16M - $18M
March
	Mid-scale Research Infrastructure-1 (Mid-scale RI-1)	NSF	$4M - $20M
May
	The Guenther Foundation - California only	Private	Varies
June
	S10 - Shared Instrumentation Grant (SIG) Program	NIH	$500K - $750K
	S10 - High-End Instrumentation (HEI) Grant Program	NIH	$751K - $2M
August
	Howard Hughes Medical Institute	Private	Varies
October
	The Guenther Foundation - California only	Private	Varies
November
	Major Research Instrumentation Program: (MRI) - Track 1	NSF	$100K - $1.4M
	Major Research Instrumentation Program: (MRI) - Track 2	NSF	$1.4M - $4M

Thermo Fisher Scientific does not guarantee (i) the accuracy or completeness of any information related to grants or funding resources or (ii) that you will receive any grant or secure any funding regardless of any assistance Thermo Fisher provides.

Thermo Fisher Financial Services

Thermo Fisher Financial Services helps you get the instrumentation and services your lab needs to achieve its research goals through a variety of funding paths that can be customized to meet your requirements.

How can you use Thermo Fisher Financial Services to fund your cryo-EM facility?

Thermo Fisher Financial Services provide various options for funding systems and services that can be used alone or in combination with internal and external funds and grants. This includes the flexible Bridge to Grant (B2G) program, which allows you to use a cryo-EM system while you wait for your grant notification in accordance with NIH guidelines.

What are your options?

The B2G program lets you achieve your cryo-EM goals while waiting for your grant to be awarded
Competitive and flexible financing
Leasing and lease-to-own options