- Vaginal swab**, genital swab, lesion swab, nasopharyngeal swab**, nasopharyngeal aspirate**, or urine sample**
Expand your molecular research offerings with infectious disease panels
A flexible, scalable, and reliable solution for lab optimization utilizing real-time PCR instrumentation
Expand your laboratory testing capabilities with PCR-based research solutions to accommodate a growing number of infectious disease areas, that enable early, accurate detection and differentiation compared to traditional methods. Detection of common infectious diseases with traditional culture- or microscopy-based methods are antiquated and lack sensitivity and specificity. Real-time PCR (qPCR) is an innovative solution for detecting slow-growing, difficult-to-cultivate, or uncultivable microorganisms.
In order to effectively study outbreaks and determine disease etiology where pathogens are similar, analytically sensitive panels are needed to support laboratory research studies.
Applied Biosystems TrueMark Infectious Disease Research Panels are convenient, duplexed TaqMan assays that are performed on pre-spotted and dried-down plates that include microorganism‑specific pathogens, utilizing real‑time PCR techniques.
This enables rapid, accurate detection and categorization of microorganisms that cause respiratory, vaginal, urinary, gastrointestinal, wound, and sexually transmitted diseases, as well as antibiotic resistance research.
Our portfolio of infectious disease panels are available in predefined and customizable options. Choose from an extensive list of pathogens to create your own plate, or ten different predefined panels in several disease states, with preselected assay targets.
Key features
Benefits of the TrueMark Predefined Plus and Custom Panels
Additional benefits of TrueMark Predefined Plus and Custom Panels
Duplexed assays
- Allow for the simultaneous detection of target and control in the same well
- Help increase confidence in results
- Are designed to reduce the need to run replicates, helping to lower cost and minimize workflow complexity
Pre-spotted and dried down plates
- Target and RNAse P or Bacillus atrophaeus* process control assays dried down in plate
- Designed to reduce hands on time and errors in the workflow
Amplification control
- One control covers all disease area targets, panels, and applications
- Makes it easier and faster for labs to implement
For Research Use Only. Not for use in diagnostic procedures.
Increased productivity, sensitivity, and specificity with qPCR technology
Implementing genetic analysis systems and solutions in the laboratory has been directly linked to improved efficiencies, cost savings, and faster time to reportable results. qPCR can detect slow-growing, difficult-to-cultivate microorganisms, making it ideal for when culture methods are inadequate, ambiguous, time-consuming, difficult, or costly.[1, 2]
Learn more about the benefits of molecular testing with this blog and on-demand webinar ›
Maximize your workflow
Expand your research testing menu with the TrueMark Infectious Disease Research Panels utilizing one workflow, with our custom, made-to-order, or predefined panels on TaqMan Array Plates for 96-well and 384-well panels which are compatible for use on QuantStudio qPCR systems. Go from sample to result in approximately four hours.
New to Thermo Fisher molecular testing? Easily click on the steps to below to see the recommended components needed to set up your laboratory for real-time PCR testing.
Use existing workflow including KingFisher systems and MagMAX kits
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- Select panel for either 96- or 384-well block plate, and add sample and Applied Biosystems multiplex master into wells
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QuantStudio 5 Dx and QuantStudio 7 Pro Dx systems are For In Vitro Diagnostic Use. Test development mode is for Research Use Only. Not for use in diagnostic procedures.
- Applied Biosystems QuantStudio Design and Analysis Software
- Vaginal swab**, genital swab, lesion swab, nasopharyngeal swab**, nasopharyngeal aspirate**, or urine sample**
Use existing workflow including KingFisher systems and MagMAX kits
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- Select panel for either 96- or 384-well block plate, and add sample and Applied Biosystems multiplex master into wells
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QuantStudio 5 Dx and QuantStudio 7 Pro Dx systems are For In Vitro Diagnostic Use. Test development mode is for Research Use Only. Not for use in diagnostic procedures.
- Applied Biosystems QuantStudio Design and Analysis Software
Analytical validation consultation services for research products
When adopting a new testing method for your research needs, we can assist in enabling the verification of the workflow to help ensure a successful launch. Our analytical validation (AV) consulting services can speed up the launch process by up to 75% and cut costs by up to half. Our expert team will consult to help develop and optimize your research workflow, while providing data analysis support and template documentation to fully maximize your instrument and reagent investment.*
* Consulting services offered for enabling the analytical validation cannot be used to validate a clinical diagnostic workflow and can only be used to support ongoing true research efforts.
TrueMark Predefined Plus Panel options
Choose from ten different predefined panels in several disease areas, covering 8 pathogens each. Pathogens included in predefined options are to be used for research purposes only.
Table 1. Applied Biosystems TrueMark Respiratory I Plus Panel
| Pathogen Type | Pathogens | Sample Type |
| Adenovirus Enterovirus Influenza A (Pan) Influenza B Respiratory Syncytial Virus A/B (RSV A/B) Rhinovirus Human Metapneumovirus (HM) SARS-CoV-2 ORF1ab |
Nasopharyngeal swab** or nasopharyngeal aspirate** | |
Control Type | RNase P internal control |
Table 2. Applied Biosystems TrueMark Respiratory II Plus Panel
| Pathogen Type | Pathogens | Sample Type |
Viral | Coronavirus 229E (CE) |
Nasopharyngeal swab** or nasopharyngeal aspirate** |
Control Type | RNase P internal control |
Table 3. Applied Biosystems TrueMark Respiratory III Plus Panel
| Pathogen Type | Pathogens | Sample Type |
Bacterial | C. pneumoniae |
Nasopharyngeal swab** or nasopharyngeal aspirate** |
Control Type | RNase P internal control |
Table 4. Applied Biosystems TrueMark Urinary I Plus Panel
| Pathogen Type | Pathogens | Sample Type |
Bacterial | Pseudomonas aeruginosa Proteus mirabilis Escherichia coli Klebsiella pneumoniae Staphylococcus aureus Coagulase negative staphylococci Staphylococcus saprophyticus |
Urine sample** |
Fungal | Candida albicans | |
Control Type | Bacillus Atrophaeus spike-in control* |
Table 5. Applied Biosystems TrueMark Urinary II Plus Panel
| Pathogen Type | Pathogens | Sample Type |
Bacterial | Corynebacterium riegelii Enterobacter aerogenes Aerococcus urinae Proteus vulgaris Acinetobacter baumannii Actinobaculum schaalii Enterococcus faecalis Streptococcus agalactiae |
Urine sample** |
Control Type | Bacillus Atrophaeus spike-in control* |
Table 6. Applied Biosystems TrueMark Urinary III Plus Panel
| Pathogen Type | Pathogens | Sample Type |
Bacterial | Citrobacter freundii |
Urine sample** |
Control Type | Bacillus Atrophaeus spike-in control* |
Table 7. Applied Biosystems TrueMark STI Plus Panel
| Pathogen Type | Pathogens | Sample Type |
Bacterial | Chlamydia trachomatis (CT) |
Vaginal swab** or genital swab |
Parasite | Trichomonas vaginalis (TV) | |
Control Type | RNase P internal control |
Table 8. Applied Biosystems TrueMark Vaginal Plus Panel
| Pathogen Type | Pathogens | Sample Type |
Bacterial | Gardnerella vaginalis (GV) |
Vaginal swab** |
Control Type | RNase P internal control |
Table 9. Applied Biosystems TrueMark Lesion Plus Panel
| Pathogen Type | Pathogens | Sample Type |
Bacterial | Haemophilus ducreyi (HD) |
Lesion swab |
Viral | Herpes simplex virus type 1 (HSV1) | |
Fungal | Pan-Candida | |
Control Type | RNase P internal control |
Table 10. Applied Biosystems TrueMark Genital Plus Panel
| Pathogen Type | Pathogens | Sample Type |
Bacterial | Gardnerella vaginalis (GV) |
Vaginal swab** or genital swab |
Fungal | Candida albicans | |
Parasite | Trichomonas vaginalis (TV) | |
Control Type | RNase P internal control |
Easy-to-Build Custom Infectious Disease Research Panels***
There is also the option to easily select and build custom infectious disease research panels, from 4 to 24 targets, in various preferred research formats, providing complete flexibility to meet the needs of each laboratory.
Custom options are available on 96-well- or 384-well plates.
Custom assay design
Ready to start building your custom panel? We offer an extensive list of microbe assays and antibiotic resistance assays in several disease areas to choose from that provide options for flexibility to customize panels that fit your laboratory's needs and priorities. Please browse through our portfolio of microbe assays and resistance gene assays.
Benefits of molecular testing
Benefits of buying from Thermo Fisher Scientific
Ordering information
TrueMark Infectious Disease Predefined Plus Panel offerings
Combo Kit components †
Catalog # | Name | Size |
Included in Combo Kit † | TrueMark Infectious Disease 1-Step Multiplex Master Mix (No ROX) | 3 X 1 mL |
TrueMark Infectious Disease Custom Panel offerings
Custom Plate Options ***
Description | Cat. No. *** |
TrueMark Respiratory Panel | |
TrueMark Urinary Panel | |
TrueMark STI and Vaginal Panels | |
TrueMark Gastrointestinal Panel | |
TrueMark Antibiotic Resistance Panel | |
TrueMark Custom Assay Panel |
For use with TrueMark Infectious Disease Custom Panels, sold separately
Additional components needs for both TrueMark Infectious Disease Predefined and Custom Panels, sold separately
For Research Use Only. Not for use in diagnostic procedures.
References
1. Finegold, David N. “Genetic Diagnostic Technologies - Fundamentals.” Merck Manuals Consumer Version, Merck Manuals, 21 Feb. 2023, https://www.merckmanuals.com/home/fundamentals/genetics/genetic-diagnostic-technologies.
2. Vazquez-Pertejo, Maria T. “Diagnosis of Infectious Disease - Infections.” Merck Manuals Consumer Version, Merck Manuals, 21 Feb. 2023, https://www.merckmanuals.com/home/infections/diagnosis-of-infectious-disease/diagnosis-of-infectious-disease.
Footnotes
*Spike in the Applied Biosystems TaqMan Universal Extraction Control Organism (Cat. No. A39180) containing Bacillus atrophaeus for use as a process control.
**Internally tested sample types.
***For specific panel options that are available with each Cat. No., contact your sales representative.
†Combo Kits include 5 TaqMan Array plates and 3 x 1 mL tubes of TrueMark Infectious Disease Multiplex Master Mix (No ROX)
Resources
For Research Use Only. Not for use in diagnostic procedures.
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