How one lab is working to meet capacity management
UCHealth responds to the increase of COVID-19 testing services in a large health care network
Style Sheet for Global Design System
The Thermo Fisher Scientific Amplitude Solution version 2.0 is an automated molecular diagnostic testing system that provides an improved streamlined workflow, uses minimal resources, and offers high throughput options, to maximize lab efficiency. Based on customer feedback, we’ve innovated to provide turnkey technology all in a total-package solution geared to help your lab be prepared for anything.
Amplitude Solution version 2.0 offers all the features you expect plus:
- Flexible sample batching—provides faster turnaround time and helps decrease cost of tests; enables running 1 to 4 extraction plates (94 to 376 samples) per run while minimizing reagent waste
- Additional sample types—enables use of saliva for less invasive sample collection using Spectrum Solutions SDNA-1000 saliva collection device
- Enhanced features—supports high test success rates through automation, which helps reduce workflow errors and sample loss rate
S-gene advantage for potential early identification of the Omicron variant (B.1.1.529)
This test uses a multi-target design that includes an S-gene target. If a sample with the 69-70del S-gene mutation is tested using the TaqPath COVID-19 High-Throughput Combo Kit, it will result in an S-gene dropout. The European CDC and U.S. FDA have noted this pattern of detection may help with early identification of the Omicron variant (B.1.1.529).
At the core of the Amplitude Solution is the Applied Biosystems TaqPath COVID-19 High-Throughput Combo Kit.
- Three assays targeting SARS-CoV-2 regions with low genetic mutation risk (orf-1ab, S, and N protein target)
- Highly sensitive and specific; offering increased accuracy and confidence in test results
- Targeted specificity to 100% of currently available complete genomes for SARS-CoV-2
- Multiplex kit available with preserved saliva, nasal and nasopharyngeal samples
- Supports an Automated PCR testing workflow
Want to learn more?
The Amplitude Solution helps position your lab as a leader in PCR testing. Scale your sample capacity with peace of mind with 24/7 access to support from the trusted source for COVID testing.
Amplitude workflow
Take a look through the highly automated workflow of the Amplitude Solution.
Module 1
- Each sample tube is uncapped, inactivated, and barcoded
- The tube rack is placed into the Tecan Fluent™ 1080 liquid handler where a negative control, beads/binding solution, proteinase K, and MS2 are added
- Four 96-deep-well plates are prepared for transfer to the next step
Module 2
- Extracts and purifies RNA from samples
- Combines 4 x 96-well RNA plates into 384-well reaction plates
- Performs real-time PCR workflow
- Separates liquid and plastic waste for easy disposal
Sample analysis
- End-to-end sample tracking and data management within the Amplitude Solution
- The qPCR run data is automatically analyzed and the COVID-19 test results are generated
- COVID-19 test results are available to be submitted to your laboratory's LIMS
Module 1
- Each sample tube is uncapped, inactivated, and barcoded
- The tube rack is placed into the Tecan Fluent™ 1080 liquid handler where a negative control, beads/binding solution, proteinase K, and MS2 are added
- Four 96-deep-well plates are prepared for transfer to the next step
Module 2
- Extracts and purifies RNA from samples
- Combines 4 x 96-well RNA plates into 384-well reaction plates
- Performs real-time PCR workflow
- Separates liquid and plastic waste for easy disposal
Sample analysis
- End-to-end sample tracking and data management within the Amplitude Solution
- The qPCR run data is automatically analyzed and the COVID-19 test results are generated
- COVID-19 test results are available to be submitted to your laboratory's LIMS
Learn more about the Amplitude Solution in action
Getting back to school requires large-scale testing
To keep campus open, North Carolina State University has established surveillance testing
The importance of trust in OEM partnerships
Thermo Fisher Scientific and Tecan have partnered to help meet COVID-19 testing demands
 | All-inclusive service partnershipOur service team will be the single point of contact you can rely on to handle everything from installation, which includes performance checks, and training to optimizing workflow applications, software, and all instrument components to help ensure your lab is quickly performing at its peak. |
 | Get answers and keep movingWe offer a rapid response 24/7, 365 days a year for both in-person and remote troubleshooting depending on your specific needs. Our service partnership includes planned maintenance visits to solve problems before they arise and on-hand locally stocked parts for those unavoidable repairs to minimize downtime and keep your lab moving forward in the fight against COVID-19. |
For Emergency Use Authorization (EUA) only. For prescription use only. For in vitro diagnostic use.
Style Sheet for Global Design System
Style Sheet for Komodo Tabs