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HLA Fundamentals: Back to Basics Series

Discover the foundational principles of Human Leukocyte Antigens (HLA) in a dynamic and engaging learning environment tailored to both newcomers and professionals in the field seeking to refresh their knowledge. This comprehensive series, led by the Linda Olsen from our technical training team, aims to provide an in-depth understanding some of the crucial aspects of transplant immunology and genetics. Participants will delve into the intricacies of HLA testing and methodologies, gaining valuable insights into the factors that influence transplant compatibility and outcomes. Join us to explore the science behind HLA. Thermo Fisher Scientific aims to be your partner in education, as we share a passion for learning and innovation in the HLA and transplant field.

Episode 1: Molecular Biology and Genetics

This episode briefly summarizes fundamental knowledge supporting the study of HLA. This will include genetic inheritance, gene expression, and population dynamics, and how genetic information flows from DNA to proteins.
 

Episode 2: Immunology

This session will focus on the processes and components of the innate and adaptive arms of the immune system, including cells, receptors, and pathways important to the understanding of HLA.
 

Episode 3: HLA Proteins and Genes

This episode focuses directly on HLA proteins and genes. It will cover the HLA system in general: the various classes and loci of HLA, their expression and roles within the human body, and specifics of HLA genetics and nomenclature.

 

Episode 4: Anti-HLA Antibodies and Immune Responses

This episode describes antibodies and possible immune responses against HLA proteins. It will cover information about antibodies in general, specific aspects of anti-HLA antibodies, and the possible immune responses in solid organ and stem cell transplant.

Episode 5: Starting with Serology: History and Evolution of HLA Assays

Episode 6: Clinical Applications of HLA Testing

Meet the speaker

Linda serves as Technical Training Specialist for our molecular products, a role she has held since March 2022. She holds a bachelor’s degree in clinical laboratory science and a master’s in public health policy and management. She has worked in HLA since 2008, with experience at the University of Utah, Stanford, and ClinImmune Labs. Prior to joining the Technical Training team, she was supervisor of the HLA lab at Mayo Clinic Arizona. She has also served as an ASHI inspector and committee member. She enjoys teaching and increasing access to educational materials on the science and application of HLA.

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These videos may contain general information relating to various medical conditions or their treatment. The information in this video is provided for informational purposes only and is not meant to be a substitute for advice provided by a doctor or other qualified health care professional. You should always consult with a doctor or other health care professional for medical advice or information about diagnosis and treatment.

Intended use of the products mentioned on this page vary. For specific intended use statements please refer to the product label.

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