Product References
oHSV-P10 reduces glioma stem cell enrichment after oncolytic HSV therapy.
Molecular therapy oncolytics
Sahu U,Mullarkey MP,Pei G,Zhao Z,Hong B,Kaur B
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Western Blot
Thu Jun 15 00:00:00 EDT 2023
Mammalian CDC14 phosphatases control exit from stemness in pluripotent cells.
The EMBO journal
Villarroya-Beltri C,Martins AFB,García A,Giménez D,Zarzuela E,Novo M,Del Álamo C,González-Martínez J,Bonel-Pérez GC,Díaz I,Guillamot M,Chiesa M,Losada A,Graña-Castro O,Rovira M,Muñoz J,Salazar-Roa M,Malumbres M
MA1-110 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to show that CDC14 phosphatases are dispensable for mitotic exit, suggesting that CDC14 phosphatases have evolved to control stemness rather than cell cycle exit and establish the CDK-CDC14 axis as a critical molecular switch for linking cell cycle regulation and self-renewal.
Wed Jan 04 00:00:00 EST 2023
Human cytomegalovirus infection perturbs neural progenitor cell fate via the expression of viral microRNAs.
Journal of medical virology
Jiang X,Liu S,Fu YR,Liu XJ,Li XJ,Yang B,Jiang HF,Shen ZZ,Alemu EA,Vazquez P,Tang Y,Kaarbø M,McVoy MA,Rayner S,Luo MH
MA1-110 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to characterize the expression of cellular and viral miRNAs in HCMV-infected NPCs during early infection by microarray and identified seven differentially expressed cellular miRNAs and six significantly upregulated HCMV miRNAs.
Wed Feb 01 00:00:00 EST 2023
Human cytomegalovirus infection perturbs neural progenitor cell fate via the expression of viral microRNAs.
Journal of medical virology
Jiang X,Liu S,Fu YR,Liu XJ,Li XJ,Yang B,Jiang HF,Shen ZZ,Alemu EA,Vazquez P,Tang Y,Kaarbø M,McVoy MA,Rayner S,Luo MH
MA1-110 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to characterize the expression of cellular and viral miRNAs in HCMV-infected NPCs during early infection by microarray and identified seven differentially expressed cellular miRNAs and six significantly upregulated HCMV miRNAs.
Wed Feb 01 00:00:00 EST 2023
Deletion of TRPC6, an Autism Risk Gene, Induces Hyperexcitability in Cortical Neurons Derived from Human Pluripotent Stem Cells.
Molecular neurobiology
Shin KC,Ali G,Ali Moussa HY,Gupta V,de la Fuente A,Kim HG,Stanton LW,Park Y
MA1-110 was used in Immunohistochemistry-immunofluorescence to provide evidence that reduction of SOCE by TRPC6 KO results in neuronal hyperexcitability, which we hypothesize is an important contributor to the cellular pathophysiology underlying hyperactivity in some ASD.
Fri Dec 01 00:00:00 EST 2023
Regulatory Mechanism between Ferritin and Mitochondrial Reactive Oxygen Species in Spinal Ligament-Derived Cells from Ossification of Posterior Longitudinal Ligament Patient.
International journal of molecular sciences
Kim JT,Kim Y,Kim JY,Lee S,Kim M,Jekarl DW
MA1-110 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to propose that enhancing ferritin levels might alleviate osteogenesis in OPLL.
Thu Feb 02 00:00:00 EST 2023
Exosomal miR-128-3p reversed fibrinogen-mediated inhibition of oligodendrocyte progenitor cell differentiation and remyelination after cerebral ischemia.
CNS neuroscience & therapeutics
Hou H,Wang Y,Yang L,Wang Y
MA1-110 was used in Immunohistochemistry-immunofluorescence to investigate the role of exosomal miR-128-3p in promoting fibrinogen-mediated inhibition of oligodendrocyte progenitor cell (OPC) differentiation and the therapeutic potential of exosomal miR-128-3p in cerebral ischemia.
Mon May 01 00:00:00 EDT 2023
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
Neuron
LaForce GR,Farr JS,Liu J,Akesson C,Gumus E,Pinkard O,Miranda HC,Johnson K,Sweet TJ,Ji P,Lin A,Coller J,Philippidou P,Wagner EJ,Schaffer AE
MA1-110 was used in Immunocytochemistry-immunoflourescence to identify a previously uncharacterized role for CLP1 in mRNA 3' end formation and reveal an mRNA misprocessing signature in neurodegeneration that may suggest a common mechanism of disease.
Wed Apr 20 00:00:00 EDT 2022
EGF signaling promotes the lineage conversion of astrocytes into oligodendrocytes.
Molecular medicine (Cambridge, Mass.)
Liu X,Li C,Li J,Xie L,Hong Z,Zheng K,Zhao X,Yang A,Xu X,Tao H,Qiu M,Yang J
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Immunocytochemistry
Wed May 04 00:00:00 EDT 2022
EGF signaling promotes the lineage conversion of astrocytes into oligodendrocytes.
Molecular medicine (Cambridge, Mass.)
Liu X,Li C,Li J,Xie L,Hong Z,Zheng K,Zhao X,Yang A,Xu X,Tao H,Qiu M,Yang J
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Immunocytochemistry
Wed May 04 00:00:00 EDT 2022
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
Nature communications
Schmidt S,Luecken MD,Trümbach D,Hembach S,Niedermeier KM,Wenck N,Pflügler K,Stautner C,Böttcher A,Lickert H,Ramirez-Suastegui C,Ahmad R,Ziller MJ,Fitzgerald JC,Ruf V,van de Berg WDJ,Jonker AJ,Gasser T,Winner B,Winkler J,Vogt Weisenhorn DM,Giesert F,Theis FJ,Wurst W
MA1-110 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to analyze human neural precursor cells (hNPCs) from sporadic PD (sPD) patients.
Tue Aug 16 00:00:00 EDT 2022
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
Nature communications
Schmidt S,Luecken MD,Trümbach D,Hembach S,Niedermeier KM,Wenck N,Pflügler K,Stautner C,Böttcher A,Lickert H,Ramirez-Suastegui C,Ahmad R,Ziller MJ,Fitzgerald JC,Ruf V,van de Berg WDJ,Jonker AJ,Gasser T,Winner B,Winkler J,Vogt Weisenhorn DM,Giesert F,Theis FJ,Wurst W
MA1-110 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to analyze human neural precursor cells (hNPCs) from sporadic PD (sPD) patients.
Tue Aug 16 00:00:00 EDT 2022
Survivin Inhibition by Piperine Sensitizes Glioblastoma Cancer Stem Cells and Leads to Better Drug Response.
International journal of molecular sciences
Warrier NM,Krishnan RK,Prabhu V,Hariharapura RC,Agarwal P,Kumar P
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Immunocytochemistry
Sat Jul 09 00:00:00 EDT 2022
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis.
Nature communications
Lopez-Fabuel I,Garcia-Macia M,Buondelmonte C,Burmistrova O,Bonora N,Alonso-Batan P,Morant-Ferrando B,Vicente-Gutierrez C,Jimenez-Blasco D,Quintana-Cabrera R,Fernandez E,Llop J,Ramos-Cabrer P,Sharaireh A,Guevara-Ferrer M,Fitzpatrick L,Thompton CD,McKay TR,Storch S,Medina DL,Mole SE,Fedichev PO,Almeida A,Bolaños JP
MA1-110 was used in Immunocytochemistry to find, in a mouse model of CLN7 neuronal ceroid lipofuscinosis, that failure in autophagy causes accumulation of structurally and bioenergetically impaired neuronal mitochondria.
Thu Jan 27 00:00:00 EST 2022
G-quadruplex DNA structures in human stem cells and differentiation.
Nature communications
Zyner KG,Simeone A,Flynn SM,Doyle C,Marsico G,Adhikari S,Portella G,Tannahill D,Balasubramanian S
MA1-110 was used in Immunocytochemistry to determine whether G-quadruplexes (G4s) are key genomic structural features linked to cellular differentiation.
Mon Jan 10 00:00:00 EST 2022
Adenomatoid odontogenic tumor: evidence for a mixed odontogenic tumor.
Oral surgery, oral medicine, oral pathology and oral radiology
Barnts K,Feng JQ,Qin C,Zhang H,Cheng YL
MA1-110 was used in Immunohistochemistry to determine through immunohistochemical staining whether adenomatoid tumors are odontogenic.
Wed Jun 01 00:00:00 EDT 2022
Refining the Role of Pyruvate Dehydrogenase Kinases in Glioblastoma Development.
Cancers
Larrieu CM,Storevik S,Guyon J,Pagano Zottola AC,Bouchez CL,Derieppe MA,Tan TZ,Miletic H,Lorens J,Tronstad KJ,Daubon T,Røsland GV
MA1-110 was used in Immunohistochemistry to confirm a reduction in tumor size and better survival of mice implanted with PDHK1 and PDHK2 knockout cells.
Tue Aug 02 00:00:00 EDT 2022
Combining HDAC and MEK Inhibitors with Radiation against Glioblastoma-Derived Spheres.
Cells
Essien EI,Hofer TP,Atkinson MJ,Anastasov N
MA1-110 was used in Immunocytochemistry-immunofluorescence to suggest that combining HDAC and MEK inhibition with radiation may offer a new strategy to improve the treatment of glioblastoma.
Wed Feb 23 00:00:00 EST 2022
NEDD4 degrades TUSC2 to promote glioblastoma progression.
Cancer letters
Rimkus TK,Arrigo AB,Zhu D,Carpenter RL,Sirkisoon S,Doheny D,Regua AT,Wong GL,Manore S,Wagner C,Lin HK,Jin G,Ruiz J,Chan M,Debinski W,Lo HW
MA1-110 was used in Immunohistochemistry to establish that NEDD4-mediated polyubiquitination is a novel mechanism for TUSC2 degradation in GBM and that TUSC2 loss promotes GBM progression in part through Bcl-xL upregulation.
Sun Apr 10 00:00:00 EDT 2022
Stem cell phenotype predicts therapeutic response in glioblastomas with MGMT promoter methylation.
Acta neuropathologica communications
Lakis NS,Brodsky AS,Karashchuk G,Audesse AJ,Yang D,Sturtevant A,Lombardo K,Wong IY,Webb AE,Anthony DC
MA1-110 was used in Immunohistochemistry to support the concept that the presence of a high stem cell phenotype in GBM, as marked by expression of SOX2 or CD133, may be associated with the clinical response to treatment.
Fri Nov 04 00:00:00 EDT 2022
Non-invasive and high-throughput interrogation of exon-specific isoform expression.
Nature cell biology
Truong DJ,Phlairaharn T,Eßwein B,Gruber C,Tümen D,Baligács E,Armbrust N,Vaccaro FL,Lederer EM,Beck EM,Geilenkeuser J,Göppert S,Krumwiede L,Grätz C,Raffl G,Schwarz D,Zirngibl M,Živanić M,Beyer M,Körner JD,Santl T,Evsyukov V,Strauß T,Schwarz SC,Höglinger GU,Heutink P,Doll S,Conrad M,Giesert F,Wurst W,Westmeyer GG
MA1-110 was used in Immunocytochemistry to confirm that MBNL1 is a dominant factor for exon 18b exclusion.
Tue Jun 01 00:00:00 EDT 2021
CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts.
Frontiers in cell and developmental biology
Park YH,Son C,Seo YM,Lee YS,Har A,Park JC
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Western Blot
Fri May 14 00:00:00 EDT 2021
Novel Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype.
Frontiers in aging neuroscience
Theunissen F,Anderton RS,Mastaglia FL,Flynn LL,Winter SJ,James I,Bedlack R,Hodgetts S,Fletcher S,Wilton SD,Laing NG,MacShane M,Needham M,Saunders A,Mackay-Sim A,Melamed Z,Ravits J,Cleveland DW,Akkari PA
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Immunocytochemistry
Fri Apr 22 00:00:00 EDT 2022
Novel Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype.
Frontiers in aging neuroscience
Theunissen F,Anderton RS,Mastaglia FL,Flynn LL,Winter SJ,James I,Bedlack R,Hodgetts S,Fletcher S,Wilton SD,Laing NG,MacShane M,Needham M,Saunders A,Mackay-Sim A,Melamed Z,Ravits J,Cleveland DW,Akkari PA
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Immunocytochemistry
Fri Apr 22 00:00:00 EDT 2022
An epilepsy-associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model.
Journal of neuroscience research
Ahn LY,Coatti GC,Liu J,Gumus E,Schaffer AE,Miranda HC
MA1-110 was used in Immunocytochemistry to investigate the molecular pathogenesis of ACTL6B p.(Val421_Cys425del) using in silico 3D protein modeling predictions and patient-specific induced pluripotent stem cell-derived neurons.
Fri Jan 01 00:00:00 EST 2021
An epilepsy-associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model.
Journal of neuroscience research
Ahn LY,Coatti GC,Liu J,Gumus E,Schaffer AE,Miranda HC
MA1-110 was used in Immunocytochemistry to investigate the molecular pathogenesis of ACTL6B p.(Val421_Cys425del) using in silico 3D protein modeling predictions and patient-specific induced pluripotent stem cell-derived neurons.
Fri Jan 01 00:00:00 EST 2021
microRNAs (miR 9, 124, 155 and 224) transdifferentiate mouse macrophages to neurons.
Experimental cell research
Challagundla N,Agrawal-Rajput R
MA1-110 was used in Immunocytochemistry to report a novel approach of microRNA (miR)- induced trans-differentiation of macrophages (CD11b high) to induced neuronal cells (iNCs) (neuronal markershigh- Nestin, Nurr1, Map2, NSE, Tubb3 and Mash1) without exogenous use of transcription factors. miR 9, 124, 155 and 224 successfully transdifferentiated macrophages to neurons with transient stem cell-like phenotype.
Sat May 01 00:00:00 EDT 2021
Glycoproteomic analysis of the changes in protein N-glycosylation during neuronal differentiation in human-induced pluripotent stem cells and derived neuronal cells.
Scientific reports
Kimura K,Koizumi T,Urasawa T,Ohta Y,Takakura D,Kawasaki N
MA1-110 was used in Western Blot to conduct sequential LC/MS/MS analyses of tryptic digest, enriched glycopeptides, and deglycosylated peptides of proteins derived from human-induced pluripotent stem cells (iPSCs) and iPSC-derived neuronal cells.
Thu May 27 00:00:00 EDT 2021
Glycoproteomic analysis of the changes in protein N-glycosylation during neuronal differentiation in human-induced pluripotent stem cells and derived neuronal cells.
Scientific reports
Kimura K,Koizumi T,Urasawa T,Ohta Y,Takakura D,Kawasaki N
MA1-110 was used in Western Blot to conduct sequential LC/MS/MS analyses of tryptic digest, enriched glycopeptides, and deglycosylated peptides of proteins derived from human-induced pluripotent stem cells (iPSCs) and iPSC-derived neuronal cells.
Thu May 27 00:00:00 EDT 2021
3D Visualization of Dynamic Cellular Reaction of Pulpal CD11c+ Dendritic Cells against Pulpitis in Whole Murine Tooth.
International journal of molecular sciences
Hong S,Park YH,Lee J,Moon J,Kong E,Jeon J,Park JC,Kim HR,Kim P
MA1-110 was used in Immunohistochemistry to demonstrate the unique capability of optical clearing-based comprehensive 3D cellular-level visualization of the whole tooth as an efficient method to analyze 3D spatiotemporal changes of various pulpal cells in normal and pathological conditions.
Wed Nov 24 00:00:00 EST 2021
3D Visualization of Dynamic Cellular Reaction of Pulpal CD11c+ Dendritic Cells against Pulpitis in Whole Murine Tooth.
International journal of molecular sciences
Hong S,Park YH,Lee J,Moon J,Kong E,Jeon J,Park JC,Kim HR,Kim P
MA1-110 was used in Immunohistochemistry to demonstrate the unique capability of optical clearing-based comprehensive 3D cellular-level visualization of the whole tooth as an efficient method to analyze 3D spatiotemporal changes of various pulpal cells in normal and pathological conditions.
Wed Nov 24 00:00:00 EST 2021
SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B.
eLife
Fan W,Tang S,Fan X,Fang Y,Xu X,Li L,Xu J,Li JL,Wang Z,Li X
MA1-110 was used in Western Blot to study sphingolipid degradation in mouse embryonic stem cells.
Thu May 27 00:00:00 EDT 2021
Ultra-hyper-fractionated radiotherapy for high-grade gliomas.
Journal of neuroscience research
Frosina G,Fontana V,Verzola D,Rosa A,Gaggero G,Garibotto G,Vagge S,Pigozzi S,Daga A
MA1-110 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to suggest investigating in the clinical setting the therapeutic effect of an ultra-hyper-FRT schedule promptly extending the conventional RT component of the current guideline ("Stupp") therapeutic protocol.
Wed Dec 01 00:00:00 EST 2021
Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit.
Cell stem cell
Morrow CS,Porter TJ,Xu N,Arndt ZP,Ako-Asare K,Heo HJ,Thompson EAN,Moore DL
MA1-110 was used in Immunocytochemistry to demonstrate that adult neural stem cells (NSCs) utilize aggresomes to recover from disrupted proteostasis and describe a novel function for the intermediate filament vimentin in proteostasis as a spatial coordinator of proteasomes to the aggresome.
Thu Apr 02 00:00:00 EDT 2020
In vitro human stem cell derived cultures to monitor calcium signaling in neuronal development and function.
Wellcome open research
Sharma Y,Saha S,Joseph A,Krishnan H,Raghu P
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Immunocytochemistry
Mon Sep 28 00:00:00 EDT 2020
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids.
eLife
Renner H,Grabos M,Becker KJ,Kagermeier TE,Wu J,Otto M,Peischard S,Zeuschner D,TsyTsyura Y,Disse P,Klingauf J,Leidel SA,Seebohm G,Schöler HR,Bruder JM
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Immunocytochemistry
Tue Nov 03 00:00:00 EST 2020
Reproducible differentiation and characterization of neurons from mouse embryonic stem cells.
MethodsX
Saxena S,Choudhury S,Mohan KN
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Immunocytochemistry
Thu Oct 22 00:00:00 EDT 2020
Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan-McDermid syndrome and autism.
Molecular autism
Breen MS,Browne A,Hoffman GE,Stathopoulos S,Brennand K,Buxbaum JD,Drapeau E
MA1-110 was used in Immunocytochemistry to investigate the molecular and pathway changes resulting from SHANK3 haploinsufficiency in Phelan-McDermid syndrome.
Fri Jun 19 00:00:00 EDT 2020
Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan-McDermid syndrome and autism.
Molecular autism
Breen MS,Browne A,Hoffman GE,Stathopoulos S,Brennand K,Buxbaum JD,Drapeau E
MA1-110 was used in Immunocytochemistry to investigate the molecular and pathway changes resulting from SHANK3 haploinsufficiency in Phelan-McDermid syndrome.
Fri Jun 19 00:00:00 EDT 2020
Bi-specific tenascin-C and fibronectin targeted peptide for solid tumor delivery.
Biomaterials
Lingasamy P,Tobi A,Haugas M,Hunt H,Paiste P,Asser T,Rätsep T,Kotamraju VR,Bjerkvig R,Teesalu T
MA1-110 was used in Immunohistochemistry to identify a novel targeting peptide (PL1, sequence: PPRRGLIKLKTS) that interacts with both oncofetal fibronectin and the tenascin-C C domain using peptide phage biopanning.
Tue Oct 01 00:00:00 EDT 2019
Comparison of in vitro Neuronal Differentiation Capacity Between Mouse Epiblast Stem Cells Derived From Nuclear Transfer and Naturally Fertilized Embryos.
Frontiers in molecular neuroscience
Li T,Zheng Y,Li Y,Ye D
MA1-110 was used in Immunocytochemistry-immunoflourescence to study the molecular and cellular mechanisms causing the inefficient perinatal and postnatal development rates of somatic cell nuclear transfer.
Wed Sep 30 00:00:00 EDT 2020
Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function.
Journal of pineal research
Mendivil-Perez M,Soto-Mercado V,Guerra-Librero A,Fernandez-Gil BI,Florido J,Shen YQ,Tejada MA,Capilla-Gonzalez V,Rusanova I,Garcia-Verdugo JM,Acuña-Castroviejo D,López LC,Velez-Pardo C,Jimenez-Del-Rio M,Ferrer JM,Escames G
Published figure using Nestin monoclonal antibody (Product # MA1-110) in Immunofluorescence
Fri Sep 01 00:00:00 EDT 2017
Comparative immunomorphology of testicular Sertoli and sertoliform tumors.
Human pathology
Mesa H,Gilles S,Datta MW,Murugan P,Larson W,Dachel S,Manivel JC
MA1110 was used in immunohistochemistry - paraffin section to develop methods to distinguish Sertoli cell tumors from sertoliform tumors
Wed Mar 01 00:00:00 EST 2017
Embryonic stem cells markers SOX2, OCT4 and Nanog expression and their correlations with epithelial-mesenchymal transition in nasopharyngeal carcinoma.
PloS one
Luo W,Li S,Peng B,Ye Y,Deng X,Yao K
MA1-110 was used in immunohistochemistry - paraffin section to assess the expression and prognostic impact of embryonic stem cell markers in nasopharyngeal carcinoma patients
Thu Aug 08 00:00:00 EDT 2013
Androgen receptors and gender-specific distribution of alkaline phosphatase in human thyroid cartilage.
Histochemistry and cell biology
Claassen H,Mönig H,Sel S,Werner JA,Paulsen F
MA1-110 was used in immunohistochemistry to study gender differences in the localization of android receptors and alkaline phosphatase in human thyroid cartilage
Fri Sep 01 00:00:00 EDT 2006
