Product References
Icariin Ameliorates Spermatogenesis Disorder in Obese Mice Induced by High-Fat Diet through Regulating the Glycolytic Pathway.
Molecular nutrition & food research
Luo M,Zhuge X,Ji L,Wang J,Mo Y,Tan Y,Zhou L,Lei X,Huang H
A11126 was used in Western Blotting to characterizes the protective effects of icariin (ICA) on spermatogenesis dysfunction in obese mice.
Sat Jul 01 00:00:00 EDT 2023
Stimulatory effects of Lycium shawii on human melanocyte proliferation, migration, and melanogenesis: In vitro and in silico studies.
Frontiers in pharmacology
Alghamdi K,Alehaideb Z,Kumar A,Al-Eidi H,Alghamdi SS,Suliman R,Ali R,Almourfi F,Alghamdi SM,Boudjelal M,Matou-Nasri S
A11126 was used in Western Blotting to reveal the molecular interactions between Metabolite 5, identified as apigenin (4,5,6-trihydroxyflavone), and the copper active site of tyrosinase, predicting enhanced tyrosinase activity and subsequent melanin formation.
Fri May 19 00:00:00 EDT 2023
Deletion of the mRNA stability factor ELAVL1 (HuR) in pancreatic cancer cells disrupts the tumor microenvironment integrity.
NAR cancer
McCarthy GA,Di Niro R,Finan JM,Jain A,Guo Y,Wyatt CR,Guimaraes AR,Waugh TA,Keith D,Morgan TK,Sears RC,Brody JR
A11126 was used in Western Blotting to identify a novel role of tumor-intrinsic human antigen R in its ability to modify the surrounding tumor microenvironment and regulate platelet-derived growth factor AA (PDGFAA).
Thu Jun 01 00:00:00 EDT 2023
Transcriptome-based network analysis related to M2-like tumor-associated macrophage infiltration identified VARS1 as a potential target for improving melanoma immunotherapy efficacy.
Journal of translational medicine
Wu Z,Lei K,Li H,He J,Shi E
A11126 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to establish an M2-like TAM-related prognostic model for melanoma and explored the role of VARS1 in melanoma progression, M2 macrophage polarization, and the development of immunotherapy resistance.
Thu Oct 27 00:00:00 EDT 2022
Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization.
Haematologica
Reed FE,Eskow NM,Min E,Carlino M,Mancuso R,Kwon N,Smith EC,Larsuel ST,Wang L,Scanlon V,Krause DS
A11126 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to demonstrate the critical importance of the Basic, LZ, and TAD domains for the proper function of MKL1 in megakaryocyte polyploidization, as directed by their roles in GEF-H1 downregulation.
Thu Dec 01 00:00:00 EST 2022
Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.
PLoS genetics
Newton S,Kong F,Carlton AJ,Aguilar C,Parker A,Codner GF,Teboul L,Wells S,Brown SDM,Marcotti W,Bowl MR
A11126 was used in Western Blot to elaborate upon the role of the neural cell adhesion molecule Neuroplastin in mammalian hearing.
Sat Jan 01 00:00:00 EST 2022
Diclofenac: A Nonsteroidal Anti-Inflammatory Drug Inducing Cancer Cell Death by Inhibiting Microtubule Polymerization and Autophagy Flux.
Antioxidants (Basel, Switzerland)
Choi S,Kim S,Park J,Lee SE,Kim C,Kang D
A11126 was used in Immunocytochemistry-immunofluorescence to investigate whether diclofenac induces cancer cell death and the mechanism by which diclofenac causes cell death.
Fri May 20 00:00:00 EDT 2022
Cur@SF NPs alleviate Friedreich's ataxia in a mouse model through synergistic iron chelation and antioxidation.
Journal of nanobiotechnology
Xu L,Sun Z,Xing Z,Liu Y,Zhao H,Tang Z,Luo Y,Hao S,Li K
A11126 was used in Western Blot to provide evidence for low-cost agent Cur@SF nanoparticles by increasing their bioavailability, suggesting their potential in the treatment of Friedrich's ataxia disease.
Wed Mar 09 00:00:00 EST 2022
Novel biallelic mutations in TTC29 cause asthenoteratospermia and male infertility.
Molecular genetics & genomic medicine
Dai S,Liang Y,Liu M,Yang Y,Liu H,Shen Y
A11126 was used in Immunocytochemistry-immunofluorescence to reveal the novel biallelic mutations in TTC29 in a MMAF patient, which findings expand the mutational spectrum of TTC29 and further contribute to the diagnosis, genetic counseling, and prognosis of male infertility.
Thu Dec 01 00:00:00 EST 2022
Establishing a Prognostic Model Based on Ulceration and Immune Related Genes in Melanoma Patients and Identification of EIF3B as a Therapeutic Target.
Frontiers in immunology
Wu Z,Lei K,Xu S,He J,Shi E
A11126 was used in Western Blotting to establish a prognostic model for melanoma and identified the role of EIF3B in melanoma progression and immunotherapy resistance development.
Mon May 02 00:00:00 EDT 2022
Brain-Derived Neurotrophic Factor Inhibits the Function of Cation-Chloride Cotransporter in a Mouse Model of Viral Infection-Induced Epilepsy.
Frontiers in cell and developmental biology
Patel DC,Thompson EG,Sontheimer H
A11126 was used in Western Blotting to investigate the role of brain-derived neurotrophic factor (BDNF) in viral-induced epilepsy in a TMEV mouse model, revealing that increased BDNF levels were associated with changes in KCC2 expression in the hippocampus during seizures, and inhibiting BDNF normalized KCC2 levels, suggesting potential strategies to control BDNF signaling for preventing seizures and epilepsy.
Sat Dec 17 00:00:00 EST 2022
CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells.
Science advances
Werder RB,Liu T,Abo KM,Lindstrom-Vautrin J,Villacorta-Martin C,Huang J,Hinds A,Boyer N,Bullitt E,Liesa M,Silverman EK,Kotton DN,Cho MH,Zhou X,Wilson AA
A11126 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to apply CRISPR interference to interrogate the function of nine genes implicated in COPD by GWAS in induced pluripotent stem cell-derived type 2 alveolar epithelial cells.
Fri Jul 15 00:00:00 EDT 2022
The FUS gene is dual-coding with both proteins contributing to FUS-mediated toxicity.
EMBO reports
Brunet MA,Jacques JF,Nassari S,Tyzack GE,McGoldrick P,Zinman L,Jean S,Robertson J,Patani R,Roucou X
A11126 was used in Western Blotting to demonstrate that FUS is a bicistronic gene and suggests that both proteins, FUS and altFUS, cooperate in toxic mechanisms.
Thu Jan 07 00:00:00 EST 2021
Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle.
Journal of virology
Yang F,Pang B,Lai KK,Cheung NN,Dai J,Zhang W,Zhang J,Chan KH,Chen H,Sze KH,Zhang H,Hao Q,Yang D,Yuen KY,Kao RY
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Mon Apr 12 00:00:00 EDT 2021
MicroRNA-155-5p Contributes to 5-Fluorouracil Resistance Through Down-Regulating TP53INP1 in Oral Squamous Cell Carcinoma.
Frontiers in oncology
Liu B,Hu J,Zhao H,Zhao L,Pan S
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Tue Jan 25 00:00:00 EST 2022
MicroRNA-155-5p Contributes to 5-Fluorouracil Resistance Through Down-Regulating TP53INP1 in Oral Squamous Cell Carcinoma.
Frontiers in oncology
Liu B,Hu J,Zhao H,Zhao L,Pan S
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Tue Jan 25 00:00:00 EST 2022
PARP inhibition in UV-associated angiosarcoma preclinical models.
Journal of cancer research and clinical oncology
Weidema ME,Desar IME,Hillebrandt-Roeffen MHS,van Erp AEM,Masuzawa M,Flucke UE,van der Graaf WTA,Versleijen-Jonkers YMH
A11126 was used in Western Blot to suggest combination treatment of olaparib and TMZ is a potential novel AS subtype-specific treatment option for UV AS patients.
Wed Sep 01 00:00:00 EDT 2021
A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment.
Theranostics
Alcaraz LB,Mallavialle A,David T,Derocq D,Delolme F,Dieryckx C,Mollevi C,Boissière-Michot F,Simony-Lafontaine J,Du Manoir S,Huesgen PF,Overall CM,Tartare-Deckert S,Jacot W,Chardès T,Guiu S,Roger P,Reinheckel T,Moali C,Liaudet-Coopman E
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Wed Jul 28 00:00:00 EDT 2021
A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment.
Theranostics
Alcaraz LB,Mallavialle A,David T,Derocq D,Delolme F,Dieryckx C,Mollevi C,Boissière-Michot F,Simony-Lafontaine J,Du Manoir S,Huesgen PF,Overall CM,Tartare-Deckert S,Jacot W,Chardès T,Guiu S,Roger P,Reinheckel T,Moali C,Liaudet-Coopman E
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Wed Jul 28 00:00:00 EDT 2021
9-Cyanopyronin probe palette for super-multiplexed vibrational imaging.
Nature communications
Miao Y,Qian N,Shi L,Hu F,Min W
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunohistochemistry
Mon Jul 26 00:00:00 EDT 2021
9-Cyanopyronin probe palette for super-multiplexed vibrational imaging.
Nature communications
Miao Y,Qian N,Shi L,Hu F,Min W
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunohistochemistry
Mon Jul 26 00:00:00 EDT 2021
Regional Differences in Heat Shock Protein 25 Expression in Brain and Spinal Cord Astrocytes of Wild-Type and SOD1 G93A Mice.
Cells
San Gil R,Clarke BE,Ecroyd H,Kalmar B,Greensmith L
A11126 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that there are differences in the expression of Hsp25 in astrocytes in different regions of the central nervous system, but Hsp25 expression is not upregulated under acute or chronic stress conditions.
Wed May 19 00:00:00 EDT 2021
NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE.
JCI insight
Georgakis S,Gkirtzimanaki K,Papadaki G,Gakiopoulou H,Drakos E,Eloranta ML,Makridakis M,Kontostathi G,Zoidakis J,Baira E,Rönnblom L,Boumpas DT,Sidiropoulos P,Verginis P,Bertsias G
A11126 was used in Western Blot to demonstrate a novel role for cleaved IL-33 alarmin decorating NETs in human SLE, linking neutrophil activation, type I IFN production, and end-organ inflammation, with skin pathology mirroring that observed in the kidneys.
Mon Nov 08 00:00:00 EST 2021
Mitotic Errors Promote Genomic Instability and Leukemia in a Novel Mouse Model of Fanconi Anemia.
Frontiers in oncology
Edwards DM,Mitchell DK,Abdul-Sater Z,Chan KK,Sun Z,Sheth A,He Y,Jiang L,Yuan J,Sharma R,Czader M,Chin PJ,Liu Y,de Cárcer G,Nalepa G,Broxmeyer HE,Clapp DW,Sierra Potchanant EA
A11126 was used in Western Blotting to illuminate the role of mitotic dysregulation in Fanconi anemia (FA)-pathway deficient malignancies in vivo, show how FANCC adjusts the spindle assembly checkpoint rheostat by regulating MAD2 kinetochore targeting in cell cycle-dependent manner, and establish two new mouse models for preclinical studies of acute myeloid leukemia.
Sat Sep 24 00:00:00 EDT 2022
Whole-genome sequencing of patients with rare diseases in a national health system.
Nature
Turro E,Astle WJ,Megy K,Gräf S,Greene D,Shamardina O,Allen HL,Sanchis-Juan A,Frontini M,Thys C,Stephens J,Mapeta R,Burren OS,Downes K,Haimel M,Tuna S,Deevi SVV,Aitman TJ,Bennett DL,Calleja P,Carss K,Caulfield MJ,Chinnery PF,Dixon PH,Gale DP,James R,Koziell A,Laffan MA,Levine AP,Maher ER,Markus HS,Morales J,Morrell NW,Mumford AD,Ormondroyd E,Rankin S,Rendon A,Richardson S,Roberts I,Roy NBA,Saleem MA,Smith KGC,Stark H,Tan RYY,Themistocleous AC,Thrasher AJ,Watkins H,Webster AR,Wilkins MR,Williamson C,Whitworth J,Humphray S,Bentley DR,Kingston N,Walker N,Bradley JR,Ashford S,Penkett CJ,Freson K,Stirrups KE,Raymond FL,Ouwehand WH
A11126 was used in Western Blot to demonstrate a synergy by using WGS for diagnosis and aetiological discovery in routine healthcare.
Wed Jul 01 00:00:00 EDT 2020
Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells.
Developmental cell
Dermit M,Dodel M,Lee FCY,Azman MS,Schwenzer H,Jones JL,Blagden SP,Ule J,Mardakheh FK
A11126 was used in Immunocytochemistry to reveal LARP6-mediated mRNA localization as a key regulator of ribosome biogenesis during cell migration and demonstrate a role for this process in cancer progression downstream of EMT.
Mon Nov 09 00:00:00 EST 2020
The Medicago truncatula DREPP Protein Triggers Microtubule Fragmentation in Membrane Nanodomains during Symbiotic Infections.
The Plant cell
Su C,Klein ML,Hernández-Reyes C,Batzenschlager M,Ditengou FA,Lace B,Keller J,Delaux PM,Ott T
A11126 was used in Immunohistochemistry (PFA fixed) to identify M. truncatula DEVELOPMENTALLY REGULATED PLASMA MEMBRANE POLYPEPTIDE (DREPP), a member of the MT binding DREPP/PCaP protein family, and investigate its functions during rhizobial infections.
Fri May 01 00:00:00 EDT 2020
Tetraspanin-7 regulation of L-type voltage-dependent calcium channels controls pancreatic β-cell insulin secretion.
The Journal of physiology
Dickerson MT,Dadi PK,Butterworth RB,Nakhe AY,Graff SM,Zaborska KE,Schaub CM,Jacobson DA
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Sun Nov 01 00:00:00 EDT 2020
Navitoclax combined with Alpelisib effectively inhibits Merkel cell carcinoma cell growth in vitro.
Therapeutic advances in medical oncology
Chteinberg E,Wetzels S,Gerritsen W,Temmerman L,van den Oord J,Biessen E,Kurz AK,Winnepenninckx V,Zenke M,Speel EJ,Zur Hausen A
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Tue Apr 19 00:00:00 EDT 2022
Navitoclax combined with Alpelisib effectively inhibits Merkel cell carcinoma cell growth in vitro.
Therapeutic advances in medical oncology
Chteinberg E,Wetzels S,Gerritsen W,Temmerman L,van den Oord J,Biessen E,Kurz AK,Winnepenninckx V,Zenke M,Speel EJ,Zur Hausen A
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Tue Apr 19 00:00:00 EDT 2022
Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo.
Journal of cancer research and clinical oncology
van Erp AEM,van Houdt L,Hillebrandt-Roeffen MHS,van Bree NFHN,Flucke UE,Mentzel T,Shipley J,Desar IME,Fleuren EDG,Versleijen-Jonkers YMH,van der Graaf WTA
A11126 was used in Western Blotting to show high PARP1 and SLFN11 expression in DSRCT tumor material and antitumor effects following olaparib and TMZ combination treatment in a preclinical DSRCT model.
Wed Jul 01 00:00:00 EDT 2020
Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo.
Journal of cancer research and clinical oncology
van Erp AEM,van Houdt L,Hillebrandt-Roeffen MHS,van Bree NFHN,Flucke UE,Mentzel T,Shipley J,Desar IME,Fleuren EDG,Versleijen-Jonkers YMH,van der Graaf WTA
A11126 was used in Western Blotting to show high PARP1 and SLFN11 expression in DSRCT tumor material and antitumor effects following olaparib and TMZ combination treatment in a preclinical DSRCT model.
Wed Jul 01 00:00:00 EDT 2020
High-intensity interval exercise increases humanin, a mitochondrial encoded peptide, in the plasma and muscle of men.
Journal of applied physiology (Bethesda, Md. : 1985)
Woodhead JST,D'Souza RF,Hedges CP,Wan J,Berridge MV,Cameron-Smith D,Cohen P,Hickey AJR,Mitchell CJ,Merry TL
A11126 was used in Western Blot to investigate whether acute high-intensity interval exercise or short-term high-intensity interval training (HIIT) impacted skeletal muscle and plasma humanin levels.
Fri May 01 00:00:00 EDT 2020
Standardized Reporter Systems for Purification and Imaging of Human Pluripotent Stem Cell-derived Motor Neurons and Other Cholinergic Cells.
Neuroscience
Garcia-Diaz A,Efe G,Kabra K,Patel A,Lowry ER,Shneider NA,Corneo B,Wichterle H
A11126 was used in Immunohistochemistry to overcome the inherent noisiness of transgene-based reporters by developing a novel series of human induced pluripotent stem cell lines.
Tue Dec 01 00:00:00 EST 2020
Besnoitia besnoiti-driven endothelial host cell cycle alteration.
Parasitology research
Velásquez ZD,Lopez-Osorio S,Pervizaj-Oruqaj L,Herold S,Hermosilla C,Taubert A
A11126 was used in Western Blotting to showed that-in terms of host cell cycle modulation-infections of bovine umbilical vein endothelial cells by B. besnoiti tachyzoites indeed differ significantly from those by T. gondii.
Sat Aug 01 00:00:00 EDT 2020
Human parainfluenza virus type 3 expressing the respiratory syncytial virus pre-fusion F protein modified for virion packaging yields protective intranasal vaccine candidates.
PloS one
Liu X,Liang B,Liu X,Amaro-Carambot E,Surman S,Kwong PD,Graham BS,Collins PL,Munir S
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Thu Apr 30 00:00:00 EDT 2020
Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate.
Cancer & metabolism
Wilde BR,Kaadige MR,Guillen KP,Butterfield A,Welm BE,Ayer DE
A11126 was used in Western Blot to investigate whether MondoA, the principal regulator of glucose-induced transcription, is required for protein synthesis inhibitors to increase thioredoxin-interacting protein expression towards potential treatment options against ER- breast tumors.
Fri Dec 04 00:00:00 EST 2020
The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides.
Nucleic acids research
Odon V,Fros JJ,Goonawardane N,Dietrich I,Ibrahim A,Alshaikhahmed K,Nguyen D,Simmonds P
A11126 was used in Western Blotting to report that ZAP similarly mediates antiviral restriction against echovirus 7 (E7) mutants with elevated frequencies of UpA dinucleotides.
Thu Sep 05 00:00:00 EDT 2019
Abemaciclib Is Effective Against Pancreatic Cancer Cells and Synergizes with HuR and YAP1 Inhibition.
Molecular cancer research : MCR
Dhir T,Schultz CW,Jain A,Brown SZ,Haber A,Goetz A,Xi C,Su GH,Xu L,Posey J,Jiang W,Yeo CJ,Golan T,Pishvaian MJ,Brody JR
A11126 was used in Western Blotting to evaluate the efficacy of abemaciclib in pre-clinical pancreatic ductal adenocarcinomas (PDAC) models in vitro and in vivo and explore its mechanism of action, and screened for potential synergistic combinations.
Tue Oct 01 00:00:00 EDT 2019
Novel Therapeutic Anti-ADAM17 Antibody A9(B8) Enhances EGFR-TKI-Mediated Anticancer Activity in NSCLC.
Translational oncology
Yang Z,Chan KI,Kwok HF,Tam KY
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Fri Nov 01 00:00:00 EDT 2019
Toxoplasma gondii-induced host cellular cell cycle dysregulation is linked to chromosome missegregation and cytokinesis failure in primary endothelial host cells.
Scientific reports
Velásquez ZD,Conejeros I,Larrazabal C,Kerner K,Hermosilla C,Taubert A
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Thu Aug 29 00:00:00 EDT 2019
Toxoplasma gondii-induced host cellular cell cycle dysregulation is linked to chromosome missegregation and cytokinesis failure in primary endothelial host cells.
Scientific reports
Velásquez ZD,Conejeros I,Larrazabal C,Kerner K,Hermosilla C,Taubert A
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Thu Aug 29 00:00:00 EDT 2019
Toxoplasma gondii-induced host cellular cell cycle dysregulation is linked to chromosome missegregation and cytokinesis failure in primary endothelial host cells.
Scientific reports
Velásquez ZD,Conejeros I,Larrazabal C,Kerner K,Hermosilla C,Taubert A
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Thu Aug 29 00:00:00 EDT 2019
Actin-microtubule interplay coordinates spindle assembly in human oocytes.
Nature communications
Roeles J,Tsiavaliaris G
A11126 was used in Immunocytochemistry-immunoflourescence to show that actin is an integral component of the meiotic machinery that closely interacts with microtubules during all major events of human oocyte maturation from the time point of spindle assembly till polar body extrusion and metaphase arrest.
Fri Oct 11 00:00:00 EDT 2019
Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion.
Cell reports
Martinez VG,Pankova V,Krasny L,Singh T,Makris S,White IJ,Benjamin AC,Dertschnig S,Horsnell HL,Kriston-Vizi J,Burden JJ,Huang PH,Tape CJ,Acton SE
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunohistochemistry
Tue Nov 26 00:00:00 EST 2019
Polymeric Nanoparticles Limit the Collective Migration of Cellular Aggregates.
Langmuir : the ACS journal of surfaces and colloids
Beaune G,Nagarajan U,Brochard-Wyart F,Winnik FM
A11126 was used in Immunocytochemistry-immunofluorescence to demonstrate that, in both cases, the spreading of the cell monolayer is slowed down in the presence of nanoparticles (NPs) and occurs only above a threshold concentration that depends on the size and surface chemistry of the NPs.
Tue Jun 11 00:00:00 EDT 2019
Human cytomegalovirus pTRS1 stimulates cap-independent translation.
Virology
Vincent HA,Ziehr B,Lenarcic EM,Moorman NJ
A11126 was used in Western Blotting to show that pTRS1 stimulates cap-independent translation and suggest a role for pTRS1 in alternative translation initiation pathways during HCMV infection.
Fri Nov 01 00:00:00 EDT 2019
Resolution limit of image analysis algorithms.
Nature communications
Cohen EAK,Abraham AV,Ramakrishnan S,Ober RJ
A11126 was used in Immunohistochemistry to develop a novel algorithmic resolution limit to evaluate the resolving capabilities of location-based image processing algorithms.
Fri Feb 15 00:00:00 EST 2019
Integration of Mesenchymal Stem Cells into a Novel Micropillar Confinement Assay.
Tissue engineering. Part C, Methods
Doolin MT,Stroka KM
A11126 was used in Immunocytochemistry-immunofluorescence to develop and demonstrate a novel process to systematically confine cells using micropillar arrays.
Fri Nov 01 00:00:00 EDT 2019
Nuclear Deformation in Response to Mechanical Confinement is Cell Type Dependent.
Cells
Doolin MT,Ornstein TS,Stroka KM
A11126 was used in Immunocytochemistry-immunoflourescence to determine how mechanical confinement affects nuclear deformation within several cell types and determine the role of cytoskeletal elements that control this.
Wed May 08 00:00:00 EDT 2019
Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy.
American journal of human genetics
Burns DT,Donkervoort S,Müller JS,Knierim E,Bharucha-Goebel D,Faqeih EA,Bell SK,AlFaifi AY,Monies D,Millan F,Retterer K,Dyack S,MacKay S,Morales-Gonzalez S,Giunta M,Munro B,Hudson G,Scavina M,Baker L,Massini TC,Lek M,Hu Y,Ezzo D,AlKuraya FS,Kang PB,Griffin H,Foley AR,Schuelke M,Horvath R,Bönnemann CG
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Thu May 03 00:00:00 EDT 2018
Grafting of Bioactive Polymers with Various Architectures: A Versatile Tool for Preparing Antibacterial Infection and Biocompatible Surfaces.
ACS applied materials & interfaces
Chouirfa H,Evans MDM,Bean P,Saleh-Mghir A,Crémieux AC,Castner DG,Falentin-Daudré C,Migonney V
A11126 was used in Immunocytochemistry-immunoflourescence to investigate three different techniques of poly(sodium styrene sulphonate) covalent grafting onto titanium surfaces and the influence of their architecture on biological responses.
Wed Jan 17 00:00:00 EST 2018
The Methyltransferase-Like Domain of Chikungunya Virus nsP2 Inhibits the Interferon Response by Promoting the Nuclear Export of STAT1.
Journal of virology
Göertz GP,McNally KL,Robertson SJ,Best SM,Pijlman GP,Fros JJ
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Sat Sep 01 00:00:00 EDT 2018
Collagen COL22A1 maintains vascular stability and mutations in COL22A1 are potentially associated with intracranial aneurysms.
Disease models & mechanisms
Ton QV,Leino D,Mowery SA,Bredemeier NO,Lafontant PJ,Lubert A,Gurung S,Farlow JL,Foroud TM,Broderick J,Sumanas S
A11126 was used in Immunocytochemistry-immunoflourescence to study the function of collagen COL22A1, and the consequences of different mutations in driving risk for intercranial aneurysms.
Wed Dec 12 00:00:00 EST 2018
Imaging of immunogold labeling in cells and tissues by helium ion microscopy.
International journal of molecular medicine
Sato C,Sato M,Ogawa S
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunocytochemistry
Sun Jul 01 00:00:00 EDT 2018
Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.
RNA biology
Vallecillo-Viejo IC,Liscovitch-Brauer N,Montiel-Gonzalez MF,Eisenberg E,Rosenthal JJC
A11126 was used in Immunocytochemistry-immunoflourescence to examine the reduction of off-target edits from site-directed RNA editing through the nuclear localisation of the editing enzyme.
Tue Jan 02 00:00:00 EST 2018
Characterisation of cellular effects of Burkholderia pseudomallei cycle inhibiting factor (Cif).
Biology open
Ng MY,Gan YH,Hagen T
A11126 was used in Western Blotting to characterise the cellular effects of Burkholderia pseudomallei cycle inhibiting factor.
Mon Jul 16 00:00:00 EDT 2018
Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer.
Cell reports
Jenks AD,Vyse S,Wong JP,Kostaras E,Keller D,Burgoyne T,Shoemark A,Tsalikis A,de la Roche M,Michaelis M,Cinatl J,Huang PH,Tanos BE
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Tue Jun 05 00:00:00 EDT 2018
Double Strand Break DNA Repair occurs via Non-Homologous End-Joining in Mouse MII Oocytes.
Scientific reports
Martin JH,Bromfield EG,Aitken RJ,Lord T,Nixon B
A11126 was used in Immunocytochemistry-immunoflourescence to determine whether mature oocytes have the capacity to detect DNA damage and subsequently mount effective repair.
Tue Jun 26 00:00:00 EDT 2018
DTX3L is upregulated in glioma and is associated with glioma progression.
International journal of molecular medicine
Xu P,Tao X,Zhao C,Huang Q,Chang H,Ban N,Bei Y,Xia X,Shen C,Wang K,Xu L,Wu P,Ren J,Wang D
A11126 was used in Western Blotting to investigate the clinical significance and biological function of Deltex-3-like in human glioma.
Tue Aug 01 00:00:00 EDT 2017
INPP5E Preserves Genomic Stability through Regulation of Mitosis.
Molecular and cellular biology
Sierra Potchanant EA,Cerabona D,Sater ZA,He Y,Sun Z,Gehlhausen J,Nalepa G
A11126 was used in immunocytochemistry to demonstrate that INPP5E regulates cell division
Wed Mar 15 00:00:00 EDT 2017
Endogenous AJAP1 associates with the cytoskeleton and attenuates angiogenesis in endothelial cells.
Biology open
Hötte K,Smyrek I,Starzinski-Powitz A,Stelzer EHK
A11126 was used in Immunocytochemistry-immunoflourescence to suggest AJAP1 as a novel tumor suppressor and diagnostic marker.
Thu Jun 15 00:00:00 EDT 2017
Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.
eLife
Al-Ramahi I,Giridharan SSP,Chen YC,Patnaik S,Safren N,Hasegawa J,de Haro M,Wagner Gee AK,Titus SA,Jeong H,Clarke J,Krainc D,Zheng W,Irvine RF,Barmada S,Ferrer M,Southall N,Weisman LS,Botas J,Marugan JJ
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Tue Dec 26 00:00:00 EST 2017
Anti-diabetic Effects of Ethanol Extract from Bitter Melon in Mice Fed a High-fat Diet.
Development & reproduction
Yoon NA,Park J,Lee J,Jeong JY,Kim HK,Lee HS,Hwang IG,Roh GS,Kim HJ,Cho GJ,Choi WS,Lee DH,Kang SS
A11126 was used in Western Blotting to indicate that BME could be effective in attenuating type 2 diabetes and could therefore be a preventive measure against type 2 diabetes.
Fri Sep 01 00:00:00 EDT 2017
Inhibition of AURKA kinase activity suppresses collective invasion in a microfluidic cell culture platform.
Scientific reports
Xia JL,Fan WJ,Zheng FM,Zhang WW,Xie JJ,Yang MY,Kamran M,Wang P,Teng HM,Wang CL,Liu Q
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Wed Jun 07 00:00:00 EDT 2017
Reciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosis.
Cell death & disease
Jana S,Hsieh AC,Gupta R
A11126 was used in Immunocytochemistry-immunoflourescence to show that PUS10, a nuclear protein, moves to mitochondria, releasing cytochrome c and SMAC during TRAIL-induced apoptosis.
Thu Oct 05 00:00:00 EDT 2017
Human Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like Response.
PLoS pathogens
Harwardt T,Lukas S,Zenger M,Reitberger T,Danzer D,Übner T,Munday DC,Nevels M,Paulus C
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Fri Jul 01 00:00:00 EDT 2016
Adenomatous polyposis coli regulates radial axonal sorting and myelination in the PNS.
Development (Cambridge, England)
Elbaz B,Traka M,Kunjamma RB,Dukala D,Brosius Lutz A,Anton ES,Barres BA,Soliven B,Popko B
A11126 was used in immunohistochemistry - frozen section to study regulation of radial axonal sorting and myelination in the PNS by adenomatous polyposis coli
Fri Jul 01 00:00:00 EDT 2016
Pellicle formation in the malaria parasite.
Journal of cell science
Kono M,Heincke D,Wilcke L,Wong TW,Bruns C,Herrmann S,Spielmann T,Gilberger TW
A11126 was used in immunocytochemistry to characterize the malaria parasite and pellicle formation
Mon Feb 15 00:00:00 EST 2016
Rho-associated protein kinase regulates subcellular localisation of Angiomotin and Hippo-signalling during preimplantation mouse embryo development.
Reproductive biomedicine online
Mihajlović AI,Bruce AW
A11126 was used in immunohistochemistry to demonstrate that Rock regulates Hippo signaling and ensures the correct subcellular localization Amot in outer cells
Thu Sep 01 00:00:00 EDT 2016
Maternal Smoke Exposure Impairs the Long-Term Fertility of Female Offspring in a Murine Model.
Biology of reproduction
Camlin NJ,Sobinoff AP,Sutherland JM,Beckett EL,Jarnicki AG,Vanders RL,Hansbro PM,McLaughlin EA,Holt JE
A11126 was used in immunocytochemistry to study impairment of long-term fertility of female offspring in a murine model by maternal smoke exposure
Mon Feb 01 00:00:00 EST 2016
Mechanism of Axonal Contractility in Embryonic Drosophila Motor Neurons In Vivo.
Biophysical journal
Tofangchi A,Fan A,Saif MTA
A11126 was used in immunohistochemistry to identify cytoskeletal components responsible for generating tension in axons
Tue Oct 04 00:00:00 EDT 2016
Resin embedded multicycle imaging (REMI): a tool to evaluate protein domains.
Scientific reports
Busse BL,Bezrukov L,Blank PS,Zimmerberg J
A11126 was used in immunocytochemistry describe a new technique based on resin-embedded multicycle imaging to study proteins in-situ
Mon Aug 08 00:00:00 EDT 2016
Forkhead Box O3A (FOXO3) and the Mitochondrial Disulfide Relay Carrier (CHCHD4) Regulate p53 Protein Nuclear Activity in Response to Exercise.
The Journal of biological chemistry
Zhuang J,Kamp WM,Li J,Liu C,Kang JG,Wang PY,Hwang PM
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Fri Nov 25 00:00:00 EST 2016
The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis.
Scientific reports
Hamdan M,Jones KT,Cheong Y,Lane SI
A11126 was used in immunocytochemistry to show a clinical relevance for the DNA damage response-induced spindle assembly checkpoint in oocytes
Mon Nov 14 00:00:00 EST 2016
DNAM-1 controls NK cell activation via an ITT-like motif.
The Journal of experimental medicine
Zhang Z,Wu N,Lu Y,Davidson D,Colonna M,Veillette A
A11126 was used in immunocytochemistry to study how DNAM-1 controls NK cell-mediated cytotoxicity and cytokine production
Mon Nov 16 00:00:00 EST 2015
Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein.
Acta neuropathologica
Navis AC,van Lith SA,van Duijnhoven SM,de Pooter M,Yetkin-Arik B,Wesseling P,Hendriks WJ,Venselaar H,Timmer M,van Cleef P,van Bergen En Henegouwen P,Best MG,Wurdinger TD,Tops BB,Leenders WP
A11126 was used in western blot to identify and characterize a novel variant of MET that is expressed in high-grade gliomas.
Wed Jul 01 00:00:00 EDT 2015
Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors.
Development (Cambridge, England)
Wu LL,Russell DL,Wong SL,Chen M,Tsai TS,St John JC,Norman RJ,Febbraio MA,Carroll J,Robker RL
A11126 was used in immunocytochemistry to show that obesity before conception imparts a reversible legacy of mitochondrial loss in offspring that is caused by ER stress
Sun Feb 15 00:00:00 EST 2015
Apolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells.
Molecular biology of the cell
Cooper S,Sadok A,Bousgouni V,Bakal C
A11126 was used in immunocytochemistry to investigate the switch between amoeboid and mesenchymal melanoma
Thu Nov 05 00:00:00 EST 2015
Mcl-1 is a key regulator of the ovarian reserve.
Cell death & disease
Omari S,Waters M,Naranian T,Kim K,Perumalsamy AL,Chi M,Greenblatt E,Moley KH,Opferman JT,Jurisicova A
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunocytochemistry
Thu May 07 00:00:00 EDT 2015
A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly.
Scientific reports
Barr AR,Bakal C
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Wed Jun 03 00:00:00 EDT 2015
Knockout of RNA Binding Protein MSI2 Impairs Follicle Development in the Mouse Ovary: Characterization of MSI1 and MSI2 during Folliculogenesis.
Biomolecules
Sutherland JM,Sobinoff AP,Gunter KM,Fraser BA,Pye V,Bernstein IR,Boon E,Siddall NA,De Andres LI,Hime GR,Holt JE,Graf T,McLaughlin EA
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Fri Jun 26 00:00:00 EDT 2015
Knockout of RNA Binding Protein MSI2 Impairs Follicle Development in the Mouse Ovary: Characterization of MSI1 and MSI2 during Folliculogenesis.
Biomolecules
Sutherland JM,Sobinoff AP,Gunter KM,Fraser BA,Pye V,Bernstein IR,Boon E,Siddall NA,De Andres LI,Hime GR,Holt JE,Graf T,McLaughlin EA
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Fri Jun 26 00:00:00 EDT 2015
Preclinical activity profile and therapeutic efficacy of the HSP90 inhibitor ganetespib in triple-negative breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Proia DA,Zhang C,Sequeira M,Jimenez JP,He S,Spector N,Shapiro GI,Tolaney S,Nagai M,Acquaviva J,Smith DL,Sang J,Bates RC,El-Hariry I
A11126 was used in immunocytochemistry to monitor the activity of HSP90 inhibitor ganetespib in triple-negative breast cancer
Wed Jan 15 00:00:00 EST 2014
Motor protein mutations cause a new form of hereditary spastic paraplegia.
Neurology
Caballero Oteyza A,Battaloğlu E,Ocek L,Lindig T,Reichbauer J,Rebelo AP,Gonzalez MA,Zorlu Y,Ozes B,Timmann D,Bender B,Woehlke G,Züchner S,Schöls L,Schüle R
A11126 was used in Immunocytochemistry-immunoflourescence to identify KIF1C as a HSP disease gene, supporting the key role of intracellular trafficking processes in the pathogenesis of hereditary axonopathies.
Tue Jun 03 00:00:00 EDT 2014
Pharmacologic suppression of JAK1/2 by JAK1/2 inhibitor AZD1480 potently inhibits IL-6-induced experimental prostate cancer metastases formation.
Molecular cancer therapeutics
Gu L,Talati P,Vogiatzi P,Romero-Weaver AL,Abdulghani J,Liao Z,Leiby B,Hoang DT,Mirtti T,Alanen K,Zinda M,Huszar D,Nevalainen MT
A11126 was used in immunohistochemistry to evaluate the effect of JAK1/2 inhibitor AZD1480 on IL-6-induced experimental prostate cancer metastases formation
Thu May 01 00:00:00 EDT 2014
A role for Ral GTPase-activating protein subunit β in mitotic regulation.
The FEBS journal
Personnic N,Lakisic G,Gouin E,Rousseau A,Gautreau A,Cossart P,Bierne H
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Tue Jul 01 00:00:00 EDT 2014
Characterization of the mitofusin 2 R94W mutation in a knock-in mouse model.
Journal of the peripheral nervous system : JPNS
Strickland AV,Rebelo AP,Zhang F,Price J,Bolon B,Silva JP,Wen R,Züchner S
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Sun Jun 01 00:00:00 EDT 2014
IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndrome.
Human molecular genetics
Aldahmesh MA,Li Y,Alhashem A,Anazi S,Alkuraya H,Hashem M,Awaji AA,Sogaty S,Alkharashi A,Alzahrani S,Al Hazzaa SA,Xiong Y,Kong S,Sun Z,Alkuraya FS
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Sun Jun 15 00:00:00 EDT 2014
Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6.
Endocrinology
Turner ML,Cronin JG,Healey GD,Sheldon IM
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Tue Apr 01 00:00:00 EDT 2014
Reprogramming cellular phenotype by soft collagen gels.
Soft matter
Ali MY,Chuang CY,Saif MT
A11126 was used in immunocytochemistry to study the effect of the mechanical stiffness of the substrate on cell phenotypes
Fri Nov 28 00:00:00 EST 2014
Adenomatous polyposis coli regulates oligodendroglial development.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Lang J,Maeda Y,Bannerman P,Xu J,Horiuchi M,Pleasure D,Guo F
A11126 was used in immunocytochemistry to study the mechanisms by which the the gut tumor suppressor APC regulates the development of oligodendroglia
Wed Feb 13 00:00:00 EST 2013
Destabilization of CDC6 upon DNA damage is dependent on neddylation but independent of Cullin E3 ligases.
The international journal of biochemistry & cell biology
Tan CY,Hagen T
A11126 was used in western blot to determine if Cullin RING E3 ligases contribute to the turnover of CDC6 protein.
Mon Jul 01 00:00:00 EDT 2013
Post-translational regulation of mTOR complex 1 in hypoxia and reoxygenation.
Cellular signalling
Tan CY,Hagen T
A11126 was used in western blot to explore how oxygen affects mTORC1 activity.
Wed May 01 00:00:00 EDT 2013
DNA damage response in male gametes of Cyrtanthus mackenii during pollen tube growth.
AoB PLANTS
Hirano T,Takagi K,Hoshino Y,Abe T
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Thu Apr 04 00:00:00 EDT 2013
DNA damage response in male gametes of Cyrtanthus mackenii during pollen tube growth.
AoB PLANTS
Hirano T,Takagi K,Hoshino Y,Abe T
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Thu Apr 04 00:00:00 EDT 2013
Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics.
BMC cancer
Brandhagen BN,Tieszen CR,Ulmer TM,Tracy MS,Goyeneche AA,Telleria CM
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Sat Jan 26 00:00:00 EST 2013
Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics.
BMC cancer
Brandhagen BN,Tieszen CR,Ulmer TM,Tracy MS,Goyeneche AA,Telleria CM
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Sat Jan 26 00:00:00 EST 2013
mTORC1 dependent regulation of REDD1 protein stability.
PloS one
Tan CY,Hagen T
A11126 was used in western blot to report that mTORC1 regulates REDD1 protein stability.
Thu Apr 17 00:00:00 EDT 2014
Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2.
PloS one
Navis AC,Bourgonje A,Wesseling P,Wright A,Hendriks W,Verrijp K,van der Laak JA,Heerschap A,Leenders WP
A11126 was used in western blot to study the therapeutic efficacy of a tyrosine kinase inhibitor active against both c-MET and VEGFR2 in a xenoraft model of human glioblastoma.
Tue Sep 03 00:00:00 EDT 2013
Atypical protein kinase Cι is required for Wnt3a-dependent neurite outgrowth and binds to phosphorylated dishevelled 2.
The Journal of biological chemistry
Greer YE,Fields AP,Brown AM,Rubin JS
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Fri Mar 29 00:00:00 EDT 2013
Atypical protein kinase Cι is required for Wnt3a-dependent neurite outgrowth and binds to phosphorylated dishevelled 2.
The Journal of biological chemistry
Greer YE,Fields AP,Brown AM,Rubin JS
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Fri Mar 29 00:00:00 EDT 2013
Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension.
Development (Cambridge, England)
Lane SI,Yun Y,Jones KT
A11126 was used in immunocytochemistry to study the role of stable kinetochore-microtubule attachments on aneuploidy.
Fri Jun 01 00:00:00 EDT 2012
Combined expression of KLK4, KLK5, KLK6, and KLK7 by ovarian cancer cells leads to decreased adhesion and paclitaxel-induced chemoresistance.
Gynecologic oncology
Loessner D,Quent VM,Kraemer J,Weber EC,Hutmacher DW,Magdolen V,Clements JA
A11126 was used in immunocytochemistry to examine the functional consequences of overexpression of KLK4-7 on ovarian cancer cells.
Sat Dec 01 00:00:00 EST 2012
A unique ball-shaped Golgi apparatus in the rat pituitary gonadotrope: its functional implications in relation to the arrangement of the microtubule network.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Watanabe T,Sakai Y,Koga D,Bochimoto H,Hira Y,Hosaka M,Ushiki T
A11126 was used in immunohistochemistry to determine the morphological characteristics of the Golgi apparatus in non-polarized endocrine cells.
Wed Aug 01 00:00:00 EDT 2012
APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing.
Molecular biology of the cell
Holt JE,Lane SI,Jennings P,García-Higuera I,Moreno S,Jones KT
A11126 was used in immunocytochemistry to propose that FZR1 is a major regulator of prometaphase
Mon Oct 01 00:00:00 EDT 2012
The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes.
PloS one
Beriault DR,Haddad O,McCuaig JV,Robinson ZJ,Russell D,Lane EB,Fudge DS
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Fri Jun 29 00:00:00 EDT 2012
The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes.
PloS one
Beriault DR,Haddad O,McCuaig JV,Robinson ZJ,Russell D,Lane EB,Fudge DS
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Fri Jun 29 00:00:00 EDT 2012
Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma.
BMC cancer
Dimberg LY,Dimberg A,Ivarsson K,Fryknäs M,Rickardson L,Tobin G,Ekman S,Larsson R,Gullberg U,Nilsson K,Öberg F,Wiklund HJ
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Sat Jul 28 00:00:00 EDT 2012
The role of the cullin-5 e3 ubiquitin ligase in the regulation of insulin receptor substrate-1.
Biochemistry research international
Hu CZ,Sethi JK,Hagen T
A11126 was used in western blot to test if Cullin-5 dependent ubiquitination regulates IRS1 protein stability
Fri Jan 11 00:00:00 EST 2013
Estrous cycle-dependent changes of Fas expression in the bovine corpus luteum: influence of keratin 8/18 intermediate filaments and cytokines.
Reproductive biology and endocrinology : RB&E
Duncan A,Forcina J,Birt A,Townson D
A11126 was used in immunocytochemistry to investigate the effect of keratin 8/18 intermediate filaments and cytokines on Fas expression in the bovine corpus luteum
Wed Oct 31 00:00:00 EDT 2012
De novo generation of cells within human nurse macrophages and consequences following HIV-1 infection.
PloS one
Gartner S,Liu Y,Natesan S
A11126 was used in immunocytochemistry to characterize a new type of nurse cell dubbed self-renewing monocytoid cells
Fri Apr 19 00:00:00 EDT 2013
Neddylation-induced conformational control regulates cullin RING ligase activity in vivo.
Journal of molecular biology
Boh BK,Smith PG,Hagen T
A11126 was used in western blot to study the effect of neddylation on Cul2 and Cul3 structure.
Fri Jun 03 00:00:00 EDT 2011
An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Vanderperre B,Staskevicius AB,Tremblay G,McCoy M,O'Neill MA,Cashman NR,Roucou X
A11126 was used in western blot to study the expression and function of overlapping open reading frames in the prion protein gene PRNP.
Fri Jul 01 00:00:00 EDT 2011
Characterization of the role of COP9 signalosome in regulating cullin E3 ubiquitin ligase activity.
Molecular biology of the cell
Choo YY,Boh BK,Lou JJ,Eng J,Leck YC,Anders B,Smith PG,Hagen T
A11126 was used in western blot to elucidate the mechanism through which COP9 signalosome promotes cullin RING ligase activity in vivo.
Thu Dec 01 00:00:00 EST 2011
Centrosomal dysregulation in human metastatic melanoma cell lines.
Cancer genetics
Charters GA,Stones CJ,Shelling AN,Baguley BC,Finlay GJ
A11126 was used in immunocytochemistry to determine the centrosomal status, ploidy, and gene status of 5 human metastatic melanoma cell lines.
Thu Sep 01 00:00:00 EDT 2011
Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720.
The Journal of biological chemistry
Chang HY,Jennings PC,Stewart J,Verrills NM,Jones KT
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Fri Apr 22 00:00:00 EDT 2011
Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720.
The Journal of biological chemistry
Chang HY,Jennings PC,Stewart J,Verrills NM,Jones KT
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Fri Apr 22 00:00:00 EDT 2011
Corticotropin releasing factor-induced CREB activation in striatal neurons occurs via a novel Gβγ signaling pathway.
PloS one
Stern CM,Luoma JI,Meitzen J,Mermelstein PG
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunocytochemistry
Wed Mar 23 00:00:00 EDT 2011
SNARE-mediated membrane traffic is required for focal adhesion kinase signaling and Src-regulated focal adhesion turnover.
Biochimica et biophysica acta
Skalski M,Sharma N,Williams K,Kruspe A,Coppolino MG
A11126 was used in western blot to test if SNARE-dependent membrane trafficking is required for integrin-mediated signaling
Sat Jan 01 00:00:00 EST 2011
Regulation of cullin RING E3 ubiquitin ligases by CAND1 in vivo.
PloS one
Chua YS,Boh BK,Ponyeam W,Hagen T
A11126 was used in western blot to suggest that CAND1 does not sequester cullins in vivo to prevent substrate receptor autoubiquitination.
Thu Jan 13 00:00:00 EST 2011
Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.
PLoS genetics
Leo L,Gherardini L,Barone V,De Fusco M,Pietrobon D,Pizzorusso T,Casari G
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Western Blot
Wed Jun 01 00:00:00 EDT 2011
CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.
PloS one
He H,Yu FX,Sun C,Luo Y
A11126 was used in western blot to review the functions of histones
Tue Nov 22 00:00:00 EST 2011
Protein kinase A-mediated phosphorylation of the RASSF1A tumour suppressor at Serine 203 and regulation of RASSF1A function.
European journal of cancer (Oxford, England : 1990)
Richter AM,Schagdarsurengin U,Rastetter M,Steinmann K,Dammann RH
A11126 was used in immunocytochemistry to examine the putative phosphorylation sites of RASSF1A and the functional consequences
Mon Nov 01 00:00:00 EDT 2010
A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating.
PLoS pathogens
Mire CE,White JM,Whitt MA
A11126 was used in immunocytochemistry and western blot to investigate the fate of incoming matrix protein from VSV during virus uncoating
Thu Jul 15 00:00:00 EDT 2010
Biochemical and cellular effects of inhibiting Nedd8 conjugation.
Biochemical and biophysical research communications
Leck YC,Choo YY,Tan CY,Smith PG,Hagen T
A11126 was used in western blot to study how Nedd8 regulates the actin cytoskeleton
Fri Jul 30 00:00:00 EDT 2010
Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria.
Cell cycle (Georgetown, Tex.)
Irvine M,Philipsz S,Frausto M,Mijatov B,Gallagher SJ,Fung C,Becker TM,Kefford RF,Rizos H
A11126 was used in western blot to investigate the mitochondrial targeting of p14ARF tumor suppressor
Mon Feb 15 00:00:00 EST 2010
Thioredoxin-interacting protein (Txnip) gene expression: sensing oxidative phosphorylation status and glycolytic rate.
The Journal of biological chemistry
Yu FX,Chai TF,He H,Hagen T,Luo Y
A11126 was used in western blot to investigate factors that regulate Txnip gene expression
Fri Aug 13 00:00:00 EDT 2010
Sperm dimorphism in terms of nuclear shape and microtubule accumulation in Cyrtanthus mackenii.
Sexual plant reproduction
Hirano T,Hoshino Y
A11126 was used in immunohistochemistry to use flow cytometry to study nuclear phase changes during generative cell division and male germ unit formation
Tue Jun 01 00:00:00 EDT 2010
Calmodulin-dependent protein kinase gamma 3 (CamKIIgamma3) mediates the cell cycle resumption of metaphase II eggs in mouse.
Development (Cambridge, England)
Chang HY,Minahan K,Merriman JA,Jones KT
A11126 was used in immunocytochemistry to study the contribution of camKIIgamma3 in transducing the oscillatory calcium signal needed to resume the cell cycle in mouse eggs
Tue Dec 01 00:00:00 EST 2009
p16INK4a-induced senescence is disabled by melanoma-associated mutations.
Aging cell
Haferkamp S,Becker TM,Scurr LL,Kefford RF,Rizos H
A11126 was used in western blot to study the effect of melanoma-associated mutations on p16INK4a-induced senescence
Wed Oct 01 00:00:00 EDT 2008
Impairment of the telomere/telomerase system and genomic instability are associated with keratinocyte immortalization induced by the skin human papillomavirus type 38.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Gabet AS,Accardi R,Bellopede A,Popp S,Boukamp P,Sylla BS,Londoño-Vallejo JA,Tommasino M
A11126 was used in immunocytochemistry to examine the effects of E6 and E7 from human papillomavirus on the telomere/telomerase system
Fri Feb 01 00:00:00 EST 2008
Biomechanical analysis of cancerous and normal cells based on bulge generation in a microfluidic device.
The Analyst
Kim YC,Park SJ,Park JK
A11126 was used in immunocytochemistry to describe a biomechanical analysis method to distinguish cancerous cells from normal cells
Wed Oct 01 00:00:00 EDT 2008
Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism.
Molecular and cellular biology
Endo Y,Beauchamp E,Woods D,Taylor WG,Toretsky JA,Uren A,Rubin JS
A11126 was used in Western Blotting to demonstrate that Frizzled3, Dishevelled and c-Jun amino-terminal kinase activity mediate Wnt-dependent neurite outgrowth in Ewing sarcoma family tumour.
Tue Apr 01 00:00:00 EDT 2008
New isoforms of rat Aquaporin-4.
Genomics
Moe SE,Sorbo JG,Sogaard R,Zeuthen T,Petter Ottersen O,Holen T
A11126 was used in Western Blotting to identify novel isoforms of rat aquaporin-4, created by alternate splicing.
Tue Apr 01 00:00:00 EDT 2008
A role for CK2 upon interkinetic nuclear migration in the cell cycle of retinal progenitor cells.
Developmental neurobiology
Carneiro AC,Fragel-Madeira L,Silva-Neto MA,Linden R
A11126 was used in immunohistochemistry - frozen section to study the contribution of CK2 to interkinetic nuclear migration
Tue Apr 01 00:00:00 EDT 2008
Localization of C. trachomatis Inc proteins in expression of their genes in HeLa cell culture.
Bulletin of experimental biology and medicine
Shkarupeta MM,Kostrjukova ES,Lazarev VN,Levitskii SA,Basovskii YI,Govorun VM
A11126 was used in immunocytochemistry to study co-localization of Chlamydia trachomatis incorporation membrane proteins with cell organelles
Fri Aug 01 00:00:00 EDT 2008
Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells.
The Journal of biological chemistry
Nakaya T,Kawai T,Suzuki T
A11126 was used in western blot to elucidate the relationship between FE65 and amyloid precursor protein
Fri Jul 04 00:00:00 EDT 2008
A mutation in CCDC50, a gene encoding an effector of epidermal growth factor-mediated cell signaling, causes progressive hearing loss.
American journal of human genetics
Modamio-Hoybjor S,Mencia A,Goodyear R,del Castillo I,Richardson G,Moreno F,Moreno-Pelayo MA
A11126 was used in Immunohistochemistry to identify a mutation in CCDC50 as the cause of hearing loss in a family with postlingual, progressive, nonsyndromic hearing loss.
Fri Jun 01 00:00:00 EDT 2007
Effect of paclitaxel on intracellular localization of c-Myc and P-c-Myc in prostate carcinoma cell lines.
Annals of the New York Academy of Sciences
Supino R,Favini E,Cuccuru G,Zunino F,Scovassi AI
A11126 was used in western blot to examine the localization and phosphorylation of c-Myc in prostate carcinoma cell lines
Mon Jan 01 00:00:00 EST 2007
A cassette system to study embryonic stem cell differentiation by inducible RNA interference.
Stem cells (Dayton, Ohio)
Wegmüller D,Raineri I,Gross B,Oakeley EJ,Moroni C
A11126 was used in western blot to develop and characterize a system where small hairpin RNAs can be induced in embryonic stem cells from a defined locus
Tue May 01 00:00:00 EDT 2007
Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization.
Cellular signalling
Chew EH,Poobalasingam T,Hawkey CJ,Hagen T
A11126 was used in western blot to study cullin-based E3 ligases in live cells
Tue May 01 00:00:00 EDT 2007
Pollen tube growth: coping with mechanical obstacles involves the cytoskeleton.
Planta
Gossot O,Geitmann A
A11126 was used in immunohistochemistry to examine the mechano-structural role of the cytoskeleton in the invasive growth of pollen tubes
Sun Jul 01 00:00:00 EDT 2007
Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD88.
FEBS letters
Nishiya T,Kajita E,Horinouchi T,Nishimoto A,Miwa S
A11126 was used in immunocytochemistry to investigate how MyD88 localization affects TLR signaling
Tue Jul 10 00:00:00 EDT 2007
Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emitters.
Biophysical journal
Egner A,Geisler C,von Middendorff C,Bock H,Wenzel D,Medda R,Andresen M,Stiel AC,Jakobs S,Eggeling C,Schönle A,Hell SW
A11126 was used in immunocytochemistry to analyze asynchronous localization of photoswitching emitters by fluorescence nanoscopy in whole cells
Thu Nov 01 00:00:00 EDT 2007
Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity.
Cancer chemotherapy and pharmacology
Henley D,Isbill M,Fernando R,Foster JS,Wimalasena J
A11126 was used in immunocytochemistry to test if cell cycle transit and or Cdc2 activity is required for paclitaxel-induced apoptosis
Thu Feb 01 00:00:00 EST 2007
Development of an AT2-deficient proximal tubule cell line for transport studies.
In vitro cellular & developmental biology. Animal
Woost PG,Kolb RJ,Chang CH,Finesilver M,Inagami T,Hopfer U
A11126 was used in immunocytochemistry to develop a transport-competent, proximal tubule cell model that lacks AT(2) as a tool to assess cellular angiotensin II regulation
Fri Feb 08 00:00:00 EST 2008
Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin.
The Journal of biological chemistry
Sharma M,Leung L,Brocardo M,Henderson J,Flegg C,Henderson BR
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunocytochemistry
Fri Jun 23 00:00:00 EDT 2006
Comprehensive examination of charged intramembrane residues in a nucleoside transporter.
The Journal of biological chemistry
Valdés R,Liu W,Ullman B,Landfear SM
A11126 was used in immunocytochemistry to study a nucleoside transporter by a comprehensive examination of charged intramembrane residues
Fri Aug 11 00:00:00 EDT 2006
The transmembrane domain is essential for the microtubular trafficking of membrane type-1 matrix metalloproteinase (MT1-MMP).
Journal of cell science
Remacle AG,Rozanov DV,Baciu PC,Chekanov AV,Golubkov VS,Strongin AY
A11126 was used in immunocytochemistry to elucidate the mechanisms that regulate the presentation of membrane type-1 matrix metalloproteinase at the cell surface
Tue Nov 01 00:00:00 EST 2005
Regulation of two insulin granule populations within the reserve pool by distinct calcium sources.
Journal of cell science
Hao M,Li X,Rizzo MA,Rocheleau JV,Dawant BM,Piston DW
A11126 was used in immunocytochemistry to investigate insulin granule trafficking
Thu Dec 15 00:00:00 EST 2005
COMMD proteins, a novel family of structural and functional homologs of MURR1.
The Journal of biological chemistry
Burstein E,Hoberg JE,Wilkinson AS,Rumble JM,Csomos RA,Komarck CM,Maine GN,Wilkinson JC,Mayo MW,Duckett CS
A11126 was used in Western Blotting to discover a novel family of proteins with structural and functional homology to MURR1.
Fri Jun 10 00:00:00 EDT 2005
Using single-particle tracking to study nuclear trafficking of viral genes.
Biophysical journal
Babcock HP,Chen C,Zhuang X
A11126 was used in Immunocytochemistry-immunoflourescence to demonstrate a physical technique allowing gene trafficking to be studied at the single-gene level.
Fri Oct 01 00:00:00 EDT 2004
Pigment cells: a model for the study of organelle transport.
Annual review of cell and developmental biology
Nascimento AA,Roland JT,Gelfand VI
A11126 was used in immunocytochemistry to study pigment cells as a model for analysis of organelle transport
Thu Feb 12 00:00:00 EST 2004
Simultaneous trichromatic fluorescence detection of proteins on Western blots using an amine-reactive dye in combination with alkaline phosphatase- and horseradish peroxidase-antibody conjugates.
Proteomics
Martin K,Hart C,Liu J,Leung WY,Patton WF
A11126 was used in western blot to discuss a trichromatic method to detect proteins
Tue Jul 01 00:00:00 EDT 2003
Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain.
Molecular biology of the cell
Hasegawa H,Zinsser S,Rhee Y,Vik-Mo EO,Davanger S,Hay JC
Published figure using alpha Tubulin monoclonal antibody (Product # A11126) in Immunofluorescence
Sat Feb 01 00:00:00 EST 2003
Inhibition of tumor necrosis factor alpha-mediated NFkappaB activation and leukocyte adhesion, with enhanced endothelial apoptosis, by G protein-linked receptor (TP) ligands.
The Journal of biological chemistry
Ashton AW,Ware GM,Kaul DK,Ware JA
A11126 was used in western blot to assess if the interaction between thromboxane A(2) and TNFalpha alters endothelial survival and leukocyte adhesion molecule expression
Fri Apr 04 00:00:00 EST 2003
A phosphatidylinositol (4,5)-bisphosphate binding site within mu2-adaptin regulates clathrin-mediated endocytosis.
The Journal of cell biology
Rohde G,Wenzel D,Haucke V
A11126 was used in western blot to investigate the role of phosphatidylinositol (4,5)-bisphosphate in clathrin-mediated endocytosis
Mon Jul 22 00:00:00 EDT 2002
Spastin, the protein mutated in autosomal dominant hereditary spastic paraplegia, is involved in microtubule dynamics.
Human molecular genetics
Errico A,Ballabio A,Rugarli EI
A11126 was used in immunocytochemistry to analyze a protein mutated in autosomal dominant hereditary spastic paraplegia called Spastin that is also involved in microtubule dynamics
Tue Jan 15 00:00:00 EST 2002
Distinct regions in the 3' untranslated region are responsible for targeting and stabilizing utrophin transcripts in skeletal muscle cells.
The Journal of cell biology
Gramolini AO,Bélanger G,Jasmin BJ
A11126 was used in immunocytochemistry to study the responsibility for stabilizing and targeting utrophin transcripts in skeletal muscle cells by distinct regions in the 3' untranslated region
Mon Sep 17 00:00:00 EDT 2001
Control of intracellular movement of connexins by E-cadherin in murine skin papilloma cells.
Experimental cell research
Hernandez-Blazquez FJ,Joazeiro PP,Omori Y,Yamasaki H
A11126 was used in immunocytochemistry to test how E-cadherin restores the function of connexins in the gap junctional intercellular communication-deficient mouse skin papilloma cell line P3/22
Thu Nov 01 00:00:00 EST 2001
Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells.
Molecular biology of the cell
Vogelsberg-Ragaglia V,Bruce J,Richter-Landsberg C,Zhang B,Hong M,Trojanowski JQ,Lee VM
A11126 was used in immunocytochemistry to examine the biological consequences of FTDP-17 tau mutants and assess their ability to form filamentous aggregates
Fri Dec 01 00:00:00 EST 2000
S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo.
The Journal of biological chemistry
Deloulme JC,Assard N,Mbele GO,Mangin C,Kuwano R,Baudier J
A11126 was used in western blot to identify S100B target proteins
Fri Nov 10 00:00:00 EST 2000
Temperature-dependent arrest of neutrophil apoptosis. Failure of Bax insertion into mitochondria at 15 degrees C prevents the release of cytochrome c.
The Journal of biological chemistry
Pryde JG,Walker A,Rossi AG,Hannah S,Haslett C
A11126 was used in western blot to study neutrophil apoptosis.
Fri Oct 27 00:00:00 EDT 2000
Alexa dyes, a series of new fluorescent dyes that yield exceptionally bright, photostable conjugates.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Panchuk-Voloshina N,Haugland RP,Bishop-Stewart J,Bhalgat MK,Millard PJ,Mao F,Leung WY,Haugland RP
A11126 was used in immunohistochemistry to compare Alexa and conventional dyes in various applications
Wed Sep 01 00:00:00 EDT 1999
The EF-hand Ca(2+)-binding protein p22 associates with microtubules in an N-myristoylation-dependent manner.
Molecular biology of the cell
Timm S,Titus B,Bernd K,Barroso M
A11126 was used in immunocytochemistry and western blot to investigate the association of p22 with microtubules
Fri Oct 01 00:00:00 EDT 1999
A luminescent ruthenium complex for ultrasensitive detection of proteins immobilized on membrane supports.
Analytical biochemistry
Berggren K,Steinberg TH,Lauber WM,Carroll JA,Lopez MF,Chernokalskaya E,Zieske L,Diwu Z,Haugland RP,Patton WF
A11126 was used in western blot to study the use of SYPRO Ruby to stain proteins
Wed Dec 15 00:00:00 EST 1999
APO2.7 defines a shared apoptotic-necrotic pathway in a breast tumor hypoxia model.
Cytometry
Koester SK,Schlossman SF,Zhang C,Decker SJ,Bolton WE
A11126 was used in flow cytometry to suggest that the anti-APO2.7 antibody can distinguish between apoptotic and incomplete apoptotic cells from necrotic breast cancer cells
Sun Nov 01 00:00:00 EST 1998
Zygotic expression of the pebble locus is required for cytokinesis during the postblastoderm mitoses of Drosophila.
Development (Cambridge, England)
Hime G,Saint R
A11126 was used in immunohistochemistry to find zygotic expression of the pebble gene in Drosophila embryogenesis is required for cytokinesis following cellularization
Wed Jan 01 00:00:00 EST 1992
