Product References
Biallelic FBXW7 knockout induces AKAP8-mediated DNA damage in neighbouring wildtype cells.
Cell death discovery
Chan DKH,Mandal A,Hester S,Yu Z,Higgins GS,Kessler BM,Fischer R,Buczacki SJA
459240 was used in Immunocytochemistry-immunofluorescence to demonstrate the importance of elucidating the local effect of cancer driver mutations between subclonal populations.
Thu Jun 29 00:00:00 EDT 2023
Enhancement of anaerobic glycolysis - a role of PGC-1α4 in resistance exercise.
Nature communications
Koh JH,Pataky MW,Dasari S,Klaus KA,Vuckovic I,Ruegsegger GN,Kumar AP,Robinson MM,Nair KS
459240 was used in Western Blotting to provide a mechanistic link between RET and improved glucose metabolism, offering an important therapeutic target to counteract aging and inactivity-induced metabolic diseases benefitting those who cannot exercise due to many reasons.
Thu Apr 28 00:00:00 EDT 2022
Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.
Nature communications
Wang X,Zhang X,Cao K,Zeng M,Fu X,Zheng A,Zhang F,Gao F,Zou X,Li H,Li M,Lv W,Xu J,Long J,Zang W,Chen J,Gao F,Ding J,Liu J,Feng Z
459240 was used in Western Blotting to reveal a vital role for complex II assembly in the development of dilated cardiomyopathy and provide additional insights into therapeutic interventions for heart diseases.
Fri Jul 08 00:00:00 EDT 2022
Elovl2-Ablation Leads to Mitochondrial Membrane Fatty Acid Remodeling and Reduced Efficiency in Mouse Liver Mitochondria.
Nutrients
Gómez Rodríguez A,Talamonti E,Naudi A,Kalinovich AV,Pauter AM,Barja G,Bengtsson T,Jacobsson A,Pamplona R,Shabalina IG
459240 was used in Western Blotting to demonstrate the role of endogenous docosahexaenoic acid (DHA) production for the normal function of mouse liver mitochondria.
Thu Jan 27 00:00:00 EST 2022
Combination of Anoectochilus roxburghii Polysaccharide and Exercise Ameliorates Diet-Induced Metabolic Disorders in Obese Mice.
Frontiers in nutrition
Chen C,Kang M,Wang Q,Liu W,Yang M,Liang S,Xiang Q,Han X,Tao J
Published figure using ATP5A1 monoclonal antibody (Product # 459240) in Western Blot
Tue Oct 26 00:00:00 EDT 2021
Combination of Anoectochilus roxburghii Polysaccharide and Exercise Ameliorates Diet-Induced Metabolic Disorders in Obese Mice.
Frontiers in nutrition
Chen C,Kang M,Wang Q,Liu W,Yang M,Liang S,Xiang Q,Han X,Tao J
Published figure using ATP5A1 monoclonal antibody (Product # 459240) in Western Blot
Tue Oct 26 00:00:00 EDT 2021
Changes in Drp1 Function and Mitochondrial Morphology Are Associated with the α-Synuclein Pathology in a Transgenic Mouse Model of Parkinson's Disease.
Cells
Portz P,Lee MK
459240 was used in Western Blotting to examine a mouse model of α-synucleinopathy for αS pathology-linked alterations in mitochondrial dynamics in vivo.
Tue Apr 13 00:00:00 EDT 2021
Tetracyclines promote survival and fitness in mitochondrial disease models.
Nature metabolism
Perry EA,Bennett CF,Luo C,Balsa E,Jedrychowski M,O'Malley KE,Latorre-Muro P,Ladley RP,Reda K,Wright PM,Gygi SP,Myers AG,Puigserver P
459240 was used in Western Blot to show that tetracyclines improve fitness of cultured mitochondrial diseases cells and ameliorate the disease in a mouse model of Leigh syndrome.
Fri Jan 01 00:00:00 EST 2021
The Alzheimer's disease-associated C99 fragment of APP regulates cellular cholesterol trafficking.
The EMBO journal
Montesinos J,Pera M,Larrea D,Guardia-Laguarta C,Agrawal RR,Velasco KR,Yun TD,Stavrovskaya IG,Xu Y,Koo SY,Snead AM,Sproul AA,Area-Gomez E
459240 was used in Western Blot to investigate the link between cholesterol homeostasis and cleavage of the amyloid precursor protein (APP), and how this relationship relates to Alzheimer's disease (AD) pathogenesis.
Thu Oct 15 00:00:00 EDT 2020
Single amino acid mutations in the Saccharomyces cerevisiae rhomboid peptidase, Pcp1p, alter mitochondrial morphology.
Cell biology international
Huddleston ME,Xiao N,Both AP,Gordon DM
Published figure using ATP5A1 monoclonal antibody (Product # 459240) in Western Blot
Wed Jan 01 00:00:00 EST 2020
Inner mitochondrial membrane protein MPV17 mutant mice display increased myocardial injury after ischemia/reperfusion.
American journal of translational research
Madungwe NB,Feng Y,Imam Aliagan A,Tombo N,Kaya F,Bopassa JC
459240 was used in Immunoprecipitation, Western Blot to investigate the role and mechanism of action of MPV17 in cardiac ischemia/reperfusion injury.
Fri May 07 00:00:00 EDT 2021
Inner mitochondrial membrane protein MPV17 mutant mice display increased myocardial injury after ischemia/reperfusion.
American journal of translational research
Madungwe NB,Feng Y,Imam Aliagan A,Tombo N,Kaya F,Bopassa JC
459240 was used in Immunoprecipitation, Western Blot to investigate the role and mechanism of action of MPV17 in cardiac ischemia/reperfusion injury.
Fri May 07 00:00:00 EDT 2021
PPARδ Attenuates Alcohol-Mediated Insulin Resistance by Enhancing Fatty Acid-Induced Mitochondrial Uncoupling and Antioxidant Defense in Skeletal Muscle.
Frontiers in physiology
Koh JH,Kim KH,Park SY,Kim YW,Kim JY
Published figure using ATP5A1 monoclonal antibody (Product # 459240) in Western Blot
Mon Sep 28 00:00:00 EDT 2020
PPARδ Attenuates Alcohol-Mediated Insulin Resistance by Enhancing Fatty Acid-Induced Mitochondrial Uncoupling and Antioxidant Defense in Skeletal Muscle.
Frontiers in physiology
Koh JH,Kim KH,Park SY,Kim YW,Kim JY
Published figure using ATP5A1 monoclonal antibody (Product # 459240) in Western Blot
Mon Sep 28 00:00:00 EDT 2020
Increased Skeletal Muscle Fiber Cross-Sectional Area, Muscle Phenotype Shift, and Altered Insulin Signaling in Rat Hindlimb Muscles in a Prenatally Androgenized Rat Model for Polycystic Ovary Syndrome.
International journal of molecular sciences
DeChick A,Hetz R,Lee J,Speelman DL
459240 was used in Western Blot, Immunohistochemistry to research into whether skeletal muscle alterations in hindlimb muscles of a PNA rate model for PCOS may represent consequences of, or adaptions to, insulin resistance in this model.
Sun Oct 25 00:00:00 EDT 2020
Increased Skeletal Muscle Fiber Cross-Sectional Area, Muscle Phenotype Shift, and Altered Insulin Signaling in Rat Hindlimb Muscles in a Prenatally Androgenized Rat Model for Polycystic Ovary Syndrome.
International journal of molecular sciences
DeChick A,Hetz R,Lee J,Speelman DL
459240 was used in Western Blot, Immunohistochemistry to research into whether skeletal muscle alterations in hindlimb muscles of a PNA rate model for PCOS may represent consequences of, or adaptions to, insulin resistance in this model.
Sun Oct 25 00:00:00 EDT 2020
Increased Skeletal Muscle Fiber Cross-Sectional Area, Muscle Phenotype Shift, and Altered Insulin Signaling in Rat Hindlimb Muscles in a Prenatally Androgenized Rat Model for Polycystic Ovary Syndrome.
International journal of molecular sciences
DeChick A,Hetz R,Lee J,Speelman DL
459240 was used in Western Blot, Immunohistochemistry to research into whether skeletal muscle alterations in hindlimb muscles of a PNA rate model for PCOS may represent consequences of, or adaptions to, insulin resistance in this model.
Sun Oct 25 00:00:00 EDT 2020
Regulation of vitamin D system in skeletal muscle and resident myogenic stem cell during development, maturation, and ageing.
Scientific reports
Srikuea R,Hirunsai M,Charoenphandhu N
459240 was used in Immunohistochemistry to investigate serum 25(OH)D3 and Ca2+ levels along with the vitamin D system in skeletal muscle and resident myogenic stem cells of male C57BL/6 mice during development, maturation, and ageing.
Tue May 19 00:00:00 EDT 2020
Regulation of vitamin D system in skeletal muscle and resident myogenic stem cell during development, maturation, and ageing.
Scientific reports
Srikuea R,Hirunsai M,Charoenphandhu N
459240 was used in Immunohistochemistry to investigate serum 25(OH)D3 and Ca2+ levels along with the vitamin D system in skeletal muscle and resident myogenic stem cells of male C57BL/6 mice during development, maturation, and ageing.
Tue May 19 00:00:00 EDT 2020
CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.
Cell
Hammerschmidt P,Ostkotte D,Nolte H,Gerl MJ,Jais A,Brunner HL,Sprenger HG,Awazawa M,Nicholls HT,Turpin-Nolan SM,Langer T,Krüger M,Brügger B,Brüning JC
459240 was used in Western Blotting to define the molecular mechanisms by which deletion of the C16:0 ceramide-producing CerS6 in mice protects from obesity and insulin resistance.
Thu May 30 00:00:00 EDT 2019
Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice.
Cell metabolism
Polyzos AA,Lee DY,Datta R,Hauser M,Budworth H,Holt A,Mihalik S,Goldschmidt P,Frankel K,Trego K,Bennett MJ,Vockley J,Xu K,Gratton E,McMurray CT
459240 was used in Western Blotting to show that region-specific neuronal vulnerability is a substrate-driven response in astrocytes.
Tue Jun 04 00:00:00 EDT 2019
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.
EMBO molecular medicine
Sprenger HG,Wani G,Hesseling A,König T,Patron M,MacVicar T,Ahola S,Wai T,Barth E,Rugarli EI,Bergami M,Langer T
459240 was used in Western Blotting to report on cell-type-specific defects in mice lacking YME1L in the nervous system.
Tue Jan 01 00:00:00 EST 2019
Absence of TXNIP in Humans Leads to Lactic Acidosis and Low Serum Methionine Linked to Deficient Respiration on Pyruvate.
Diabetes
Katsu-Jiménez Y,Vázquez-Calvo C,Maffezzini C,Halldin M,Peng X,Freyer C,Wredenberg A,Giménez-Cassina A,Wedell A,Arnér ESJ
459240 was used in Western Blotting to study a family with a mutation in the TXNIP gene leading to nondetectable expression of TXNIP protein.
Mon Apr 01 00:00:00 EDT 2019
Effects of prolonged type 2 diabetes on mitochondrial function in cerebral blood vessels.
American journal of physiology. Heart and circulatory physiology
Merdzo I,Rutkai I,Sure VNLR,Katakam PVG,Busija DW
459240 was used in Western Blotting to characterise the dynamics of mitochondrial function during the progression of type 2 diabetes mellitus with regard to mitochondrial respiration, protein expression, and reactive oxygen species production.
Fri Nov 01 00:00:00 EDT 2019
Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis.
Acta neuropathologica communications
Wimmer I,Scharler C,Zrzavy T,Kadowaki T,Mödlagl V,Rojc K,Tröscher AR,Kitic M,Ueda S,Bradl M,Lassmann H
459240 was used in Immunohistochemistry to show that naive LEWzizi rats show a spontaneous phenotype partly mimicking the changes seen in human aging and particularly in the normal-appearing white and grey matter of patients with progressive MS.
Thu Jan 31 00:00:00 EST 2019
L-Arabinose Elicits Gut-Derived Hydrogen Production and Ameliorates Metabolic Syndrome in C57BL/6J Mice on High-Fat-Diet.
Nutrients
Zhao L,Wang Y,Zhang G,Zhang T,Lou J,Liu J
459240 was used in Western Blot to show oral L-arabinose elicited immediate and robust release of hydrogen in mice in a dose-and-time-dependent manner while alleviating high-fat-diet induced metabolic syndrome.
Fri Dec 13 00:00:00 EST 2019
MTSS1/Src family kinase dysregulation underlies multiple inherited ataxias.
Proceedings of the National Academy of Sciences of the United States of America
Brown AS,Meera P,Altindag B,Chopra R,Perkins EM,Paul S,Scoles DR,Tarapore E,Magri J,Huang H,Jackson M,Shakkottai VG,Otis TS,Pulst SM,Atwood SX,Oro AE
459240 was used in Immunohistochemistry on paraffin embedded tissues to identify a common SCA therapeutic target and demonstrate a key role for MTSS1/SFK in Purkinje neuron survival and ataxia progression.
Wed Dec 26 00:00:00 EST 2018
Cardiac CaMKII activation promotes rapid translocation to its extra-dyadic targets.
Journal of molecular and cellular cardiology
Wood BM,Simon M,Galice S,Alim CC,Ferrero M,Pinna NN,Bers DM,Bossuyt J
459240 was used in Immunocytochemistry to demonstrate active CaMKII mobilisation can be activated in high calcium regions resulting in translocation to distant myocyte target sites.
Sat Dec 01 00:00:00 EST 2018
Dynamic association of human mRNP proteins with mitochondrial tRNAs in the cytosol.
RNA (New York, N.Y.)
Jády BE,Ketele A,Kiss T
459240 was used in Western Blotting to show mitochondrial tRNAs interact with human mRNP proteins YBX1 and YBX3 in cytosol.
Sat Dec 01 00:00:00 EST 2018
Dynamic association of human mRNP proteins with mitochondrial tRNAs in the cytosol.
RNA (New York, N.Y.)
Jády BE,Ketele A,Kiss T
459240 was used in Western Blotting to show mitochondrial tRNAs interact with human mRNP proteins YBX1 and YBX3 in cytosol.
Sat Dec 01 00:00:00 EST 2018
Dynamic association of human mRNP proteins with mitochondrial tRNAs in the cytosol.
RNA (New York, N.Y.)
Jády BE,Ketele A,Kiss T
459240 was used in Western Blotting to show mitochondrial tRNAs interact with human mRNP proteins YBX1 and YBX3 in cytosol.
Sat Dec 01 00:00:00 EST 2018
Impaired Mitochondrial Respiration in Large Cerebral Arteries of Rats with Type 2 Diabetes.
Journal of vascular research
Merdzo I,Rutkai I,Sure VN,McNulty CA,Katakam PV,Busija DW
459240 was used in western blot to evaluate the mitochondrial dynamics of the cerebral vasculature of 14-week-old Zucker diabetic fatty obese rats with early type 2 diabetes
Tue May 09 00:00:00 EDT 2017
Control of mitochondrial function and cell growth by the atypical cadherin Fat1.
Nature
Cao LL,Riascos-Bernal DF,Chinnasamy P,Dunaway CM,Hou R,Pujato MA,O'Rourke BP,Miskolci V,Guo L,Hodgson L,Fiser A,Sibinga NE
459240 was used in immunoprecipitation and western blot to demonstrate that Fat1 cadherin represses mitochondrial respiration that regulates vascular smooth muscle cell proliferation after arterial injury
Thu Nov 24 00:00:00 EST 2016
Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue.
Acta neuropathologica
Winter L,Wittig I,Peeva V,Eggers B,Heidler J,Chevessier F,Kley RA,Barkovits K,Strecker V,Berwanger C,Herrmann H,Marcus K,Kornblum C,Kunz WS,Schröder R,Clemen CS
459240 was used in western blot show that mutant desmin expression results in mitochondrial damage during early stages of desminopathies
Thu Sep 01 00:00:00 EDT 2016
Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.
The Journal of cell biology
Korwitz A,Merkwirth C,Richter-Dennerlein R,Tröder SE,Sprenger HG,Quirós PM,López-Otín C,Rugarli EI,Langer T
459240 was used in western blot to analyze delay of neurodegeneration by preventing stress-induced OPA1 processing in mitochondria by loss of OMA1
Mon Jan 18 00:00:00 EST 2016
Two different pathogenic mechanisms, dying-back axonal neuropathy and pancreatic senescence, are present in the YG8R mouse model of Friedreich's ataxia.
Disease models & mechanisms
Mollá B,Riveiro F,Bolinches-Amorós A,Muñoz-Lasso DC,Palau F,González-Cabo P
Published figure using ATP Synthase alpha monoclonal antibody (Product # 459240) in Western Blot
Wed Jun 01 00:00:00 EDT 2016
Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis.
Journal of cell science
Mukherjee R,Chakrabarti O
459240 was used in Flow Cytometry, Immunocytochemistry, Western Blot to elucidate a new interaction between the cytosolic E3 ligase mahogunin RING finger 1 (MGRN1) and the endoplasmic reticulum (ER) ubiquitin E3 ligase GP78 (also known as AMFR).
Mon Feb 15 00:00:00 EST 2016
CCN6 regulates mitochondrial function.
Journal of cell science
Patra M,Mahata SK,Padhan DK,Sen M
459240 was used in western blot to determine regulation of mitochondrial function via a Wnt induced signaling protein-3 called CCN6
Fri Jul 15 00:00:00 EDT 2016
The mitochondrial function of the cerebral vasculature in insulin-resistant Zucker obese rats.
American journal of physiology. Heart and circulatory physiology
Merdzo I,Rutkai I,Tokes T,Sure VN,Katakam PV,Busija DW
459240 was used in western blot to study cerebral vasculature mitochondrial function in insulin-resistant Zucker obese rats
Fri Apr 01 00:00:00 EDT 2016
Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.
Nature communications
Beck SJ,Guo L,Phensy A,Tian J,Wang L,Tandon N,Gauba E,Lu L,Pascual JM,Kroener S,Du H
Published figure using ATP Synthase alpha monoclonal antibody (Product # 459240) in Western Blot
Fri May 06 00:00:00 EDT 2016
Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries.
American journal of physiology. Heart and circulatory physiology
Rutkai I,Dutta S,Katakam PV,Busija DW
459240 was used in western blot to test if mitochondrial energetics of large cerebral arteries are sex dependent.
Sun Nov 01 00:00:00 EDT 2015
Differentiation-Associated Downregulation of Poly(ADP-Ribose) Polymerase-1 Expression in Myoblasts Serves to Increase Their Resistance to Oxidative Stress.
PloS one
Oláh G,Szczesny B,Brunyánszki A,López-García IA,Gerö D,Radák Z,Szabo C
459240 was used in western blot to assess the role of PARP-1 in a murine skeletal muscle differentiation model and compare the responses to oxidative stress of undifferentiated myoblasts and differentiated myotubes.
Tue May 10 00:00:00 EDT 2016
Differentiation-Associated Downregulation of Poly(ADP-Ribose) Polymerase-1 Expression in Myoblasts Serves to Increase Their Resistance to Oxidative Stress.
PloS one
Oláh G,Szczesny B,Brunyánszki A,López-García IA,Gerö D,Radák Z,Szabo C
459240 was used in western blot to assess the role of PARP-1 in a murine skeletal muscle differentiation model and compare the responses to oxidative stress of undifferentiated myoblasts and differentiated myotubes.
Tue May 10 00:00:00 EDT 2016
α-Synuclein is localized to mitochondria-associated ER membranes.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Guardia-Laguarta C,Area-Gomez E,Rüb C,Liu Y,Magrané J,Becker D,Voos W,Schon EA,Przedborski S
459240 was used in western blot to demonstrate that wildtype α-synuclein localizes mitochondria-associated endoplasmic reticulum membranes and that mutated α-synuclein behaves differently.
Wed Jan 01 00:00:00 EST 2014
Sustained mitochondrial functioning in cerebral arteries after transient ischemic stress in the rat: a potential target for therapies.
American journal of physiology. Heart and circulatory physiology
Rutkai I,Katakam PV,Dutta S,Busija DW
459240 was used in western blot to test if mitochondrial function in the cerebral vasculature is maintained after transient middle cerebral artery occlusion in rats
Wed Oct 01 00:00:00 EDT 2014
Effect of moderate dietary restriction on visceral organ weight, hepatic oxygen consumption, and metabolic proteins associated with energy balance in mature pregnant beef cows.
Journal of animal science
Wood KM,Awda BJ,Fitzsimmons C,Miller SP,McBride BW,Swanson KC
459240 was used in western blot to study the effect of dietary restriction on the abundance of selected proteins regulating cellular energy metabolism in cows.
Sun Sep 01 00:00:00 EDT 2013
Influence of pregnancy in mid-to-late gestation on circulating metabolites, visceral organ mass, and abundance of proteins relating to energy metabolism in mature beef cows.
Journal of animal science
Wood KM,Awda BJ,Fitzsimmons C,Miller SP,McBride BW,Swanson KC
459240 was used in western blot to investigate the effect of pregnancy on BW change, carcass traits, visceral organ mass, and circulating serum metabolites in cows.
Sun Dec 01 00:00:00 EST 2013
Effects of SRC and STAT3 upon gap junctional, intercellular communication in lung cancer lines.
Anticancer research
Geletu M,Guy S,Raptis L
459240 was used in western blot to determine the contribution of the SRC/STAT3 axis to gap junctional communication suppression.
Tue Oct 01 00:00:00 EDT 2013
Mitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal cultures.
PloS one
Wappler EA,Institoris A,Dutta S,Katakam PV,Busija DW
459240 was used in western blot to investigate the mitochondrial dynamics in rat neurons following oxygen-glucose deprivation
Wed Dec 04 00:00:00 EST 2013
Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart.
Nature communications
Hoshino A,Mita Y,Okawa Y,Ariyoshi M,Iwai-Kanai E,Ueyama T,Ikeda K,Ogata T,Matoba S
459240 was used in western blot to test if mitochondrial quality control mechanisms contribute to the development of cardiac dysfunction.
Thu Feb 27 00:00:00 EST 2014
