Product References
Distinct SARS-CoV-2 specific NLRP3 and IL-1β responses in T cells of aging patients during acute COVID-19 infection.
Frontiers in immunology
Mahalingam SS,Jayaraman S,Arunkumar A,Dudley HM,Anthony DD,Shive CL,Jacobson JM,Pandiyan P
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance.
Disease markers
Zhang Y,Chang Y,Han Z,Ma K,Zeng X,Li L
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Tue Oct 18 00:00:00 EDT 2022
Plasma Extracellular Vesicle Subtypes May be Useful as Potential Biomarkers of Immune Activation in People With HIV.
Pathogens & immunity
Bazié WW,Boucher J,Vitry J,Goyer B,Routy JP,Tremblay C,Trottier S,Jenabian MA,Provost P,Alary M,Gilbert C
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Sat Apr 23 00:00:00 EDT 2022
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.
Journal of neuroinflammation
Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Thu Feb 18 00:00:00 EST 2021
A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity.
Molecular therapy oncolytics
Hammill JA,Kwiecien JM,Dvorkin-Gheva A,Lau VWC,Baker C,Wu Y,Bezverbnaya K,Aarts C,Heslen CW,Denisova GF,Derocher H,Milne K,Nelson BH,Bramson JL
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
The Potential of Nanobody-Targeted Photodynamic Therapy to Trigger Immune Responses.
Cancers
Beltrán Hernández I,Angelier ML,Del Buono D'Ondes T,Di Maggio A,Yu Y,Oliveira S
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Wed Apr 15 00:00:00 EDT 2020
Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab.
Nature communications
Serra-Peinado C,Grau-Expósito J,Luque-Ballesteros L,Astorga-Gamaza A,Navarro J,Gallego-Rodriguez J,Martin M,Curran A,Burgos J,Ribera E,Raventós B,Willekens R,Torrella A,Planas B,Badía R,Garcia F,Castellví J,Genescà M,Falcó V,Buzon MJ
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Fri Aug 16 00:00:00 EDT 2019
Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients.
Oncology letters
Chen X,Wang Y,Wang J,Wen J,Jia X,Wang X,Zhang H
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2018
IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.
Nature communications
Hsieh WC,Hsu TS,Chang YJ,Lai MZ
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Wed Jan 31 00:00:00 EST 2018
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.
Nature communications
Arbore G,West EE,Rahman J,Le Friec G,Niyonzima N,Pirooznia M,Tunc I,Pavlidis P,Powell N,Li Y,Liu P,Servais A,Couzi L,Fremeaux-Bacchi V,Placais L,Ferraro A,Walsh PR,Kavanagh D,Afzali B,Lavender P,Lachmann HJ,Kemper C
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Wed Oct 10 00:00:00 EDT 2018
Ex vivo culture of human atherosclerotic plaques: A model to study immune cells in atherogenesis.
Atherosclerosis
Lebedeva A,Vorobyeva D,Vagida M,Ivanova O,Felker E,Fitzgerald W,Danilova N,Gontarenko V,Shpektor A,Vasilieva E,Margolis L
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice.
The Journal of biological chemistry
Dimitrov V,Bouttier M,Boukhaled G,Salehi-Tabar R,Avramescu RG,Memari B,Hasaj B,Lukacs GL,Krawczyk CM,White JH
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Fri Dec 15 00:00:00 EST 2017
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Thu Aug 03 00:00:00 EDT 2017
Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis.
Stem cell reports
Li Y,Brauer PM,Singh J,Xhiku S,Yoganathan K,Zúñiga-Pflücker JC,Anderson MK
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Tue Sep 12 00:00:00 EDT 2017
PD-L1 expression and prognostic impact in glioblastoma.
Neuro-oncology
Nduom EK,Wei J,Yaghi NK,Huang N,Kong LY,Gabrusiewicz K,Ling X,Zhou S,Ivan C,Chen JQ,Burks JK,Fuller GN,Calin GA,Conrad CA,Creasy C,Ritthipichai K,Radvanyi L,Heimberger AB
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Impact of HIV-1 Membrane Cholesterol on Cell-Independent Lytic Inactivation and Cellular Infectivity.
Biochemistry
Kalyana Sundaram RV,Li H,Bailey L,Rashad AA,Aneja R,Weiss K,Huynh J,Bastian AR,Papazoglou E,Abrams C,Wrenn S,Chaiken I
13-0048 was used in an ELISA assay to investigate the role of envelope cholesterol on p24 release to better understand the PTT-triggered membrane transformation involved.
Tue Jan 26 00:00:00 EST 2016
Tax and Semaphorin 4D Released from Lymphocytes Infected with Human Lymphotropic Virus Type 1 and Their Effect on Neurite Growth.
AIDS research and human retroviruses
Quintremil S,Alberti C,Rivera M,Medina F,Puente J,Cartier L,Ramírez E,Tanaka Y,Valenzuela MA
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets.
Scientific reports
Muller L,Mitsuhashi M,Simms P,Gooding WE,Whiteside TL
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2016
Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16): MECHANISTIC INSIGHTS AND NEW THERAPEUTIC OPPORTUNITIES.
The Journal of biological chemistry
Hall G,Cullen E,Sawmynaden K,Arnold J,Fox S,Cowan R,Muskett FW,Matthews D,Merritt A,Kettleborough C,Cruikshank W,Taylor D,Bayliss R,Carr MD
13-0048 was used in Flow cytometry/Cell sorting to reveal a surprising mechanism of action for IL-16 bound antibodies and identifies new opportunities for the development of IL-16-targeted therapeutics.
Fri Aug 05 00:00:00 EDT 2016
The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals.
Journal of virology
Veillette M,Coutu M,Richard J,Batraville LA,Dagher O,Bernard N,Tremblay C,Kaufmann DE,Roger M,Finzi A
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV-1 by Peptide Triazole Thiols.
ACS chemical biology
Bailey LD,Kalyana Sundaram RV,Li H,Duffy C,Aneja R,Rosemary Bastian A,Holmes AP,Kamanna K,Rashad AA,Chaiken I
13-0048 was used in an ELISA assay to investigate the mode of action underlying lytic inactivation of HIV-1 virions by peptide triazole thiol.
Fri Dec 18 00:00:00 EST 2015
Oncogenic NRAS hyper-activates multiple pathways in human cord blood stem/progenitor cells and promotes myelomonocytic proliferation in vivo.
American journal of translational research
Wang T,Li C,Xia C,Dong Y,Yang D,Geng Y,Cai J,Zhang J,Zhang X,Wang J
13-0048 was used in Flow cytometry/Cell sorting to evaluate the effects of the NRASG12D mutation on human haematopoiesis and leukaemogenesis in vitro and in vivo.
Tue Dec 22 00:00:00 EST 2015
Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans.
Journal of immunology (Baltimore, Md. : 1950)
Wertheimer AM,Bennett MS,Park B,Uhrlaub JL,Martinez C,Pulko V,Currier NL,Nikolich-Žugich D,Kaye J,Nikolich-Žugich J
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Flow Cytometry
Sat Mar 01 00:00:00 EST 2014
Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancy.
Biochemistry
Emileh A,Duffy C,Holmes AP,Rosemary Bastian A,Aneja R,Tuzer F,Rajagopal S,Li H,Abrams CF,Chaiken IM
13-0048 was used in an ELISA assay to study the interactions in the complex formed between the HIV-1 gp120 glycoprotein and a peptide triazole.
Tue Jun 03 00:00:00 EDT 2014
An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinoma.
PloS one
Tang Y,Xu X,Guo S,Zhang C,Tang Y,Tian Y,Ni B,Lu B,Wang H
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Immunohistochemistry
Tue Jan 06 00:00:00 EST 2015
HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA).
PloS one
Hioe CE,Tuen M,Vasiliver-Shamis G,Alvarez Y,Prins KC,Banerjee S,Nádas A,Cho MW,Dustin ML,Kachlany SC
13-0048 was used in Flow cytometry/Cell sorting to evaluate whether cellular activation can be induced by HIV itself, showing that gp120 activates LFA-1 on CD4 T-lymphocytes.
Thu Feb 02 00:00:00 EST 2012
Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates.
Journal of virology
Douagi I,Forsell MN,Sundling C,O'Dell S,Feng Y,Dosenovic P,Li Y,Seder R,Loré K,Mascola JR,Wyatt RT,Karlsson Hedestam GB
13-0048 was used in Immuno-assay to investigate the impact of in vivo soluble HIV-1 envelope glycoprotein-CD4 interactions during vaccination.
Mon Feb 01 00:00:00 EST 2010
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Western Blot
Thu Feb 26 00:00:00 EST 2009
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Western Blot
Thu Feb 26 00:00:00 EST 2009
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Western Blot
Thu Feb 26 00:00:00 EST 2009
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Published figure using CD4 monoclonal antibody (Product # 13-0048-82) in Western Blot
Thu Feb 26 00:00:00 EST 2009
B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.
PLoS pathogens
Forsell MN,Dey B,Mörner A,Svehla K,O'dell S,Högerkorp CM,Voss G,Thorstensson R,Shaw GM,Mascola JR,Karlsson Hedestam GB,Wyatt RT
13-0048 was used in Binding experiments to investigate the mechanism leading to the production of antibodies against the co-receptor binding site of HIV-1 and gp120.
Fri Oct 03 00:00:00 EDT 2008
