Product References
Three-dimensional growth reveals fine-tuning of 5-lipoxygenase by proliferative pathways in cancer.
Life science alliance
Göbel T,Goebel B,Hyprath M,Lamminger I,Weisser H,Angioni C,Mathes M,Thomas D,Kahnt AS
PA5-34663 was used in Western Blotting to show that tumor cells fine-tune 5-LO and LT biosynthesis in response to environmental changes repressing the enzyme during proliferation while making use of the enzyme under cell stress conditions, implying that tumor-derived 5-LO plays a role in the manipulation of the tumor stroma to quickly restore cell proliferation.
Mon May 01 00:00:00 EDT 2023
Immunohistochemical Expression Pattern of FGFR1, FGFR2, RIP5, and HIP2 in Developing and Postnatal Kidneys of (yotari) Mice.
International journal of molecular sciences
Kelam N,Racetin A,Katsuyama Y,Vukojević K,Kostić S
PA5-34663 was used in Immunohistochemistry to emphasize the crucial function of the examined markers throughout normal kidney development and their potential participation in kidney pathology and diagnostics, where they might serve as biomarkers and therapeutic targets.
Fri Feb 11 00:00:00 EST 2022
Immunohistochemical Expression Pattern of FGFR1, FGFR2, RIP5, and HIP2 in Developing and Postnatal Kidneys of (yotari) Mice.
International journal of molecular sciences
Kelam N,Racetin A,Katsuyama Y,Vukojević K,Kostić S
PA5-34663 was used in Immunohistochemistry to emphasize the crucial function of the examined markers throughout normal kidney development and their potential participation in kidney pathology and diagnostics, where they might serve as biomarkers and therapeutic targets.
Fri Feb 11 00:00:00 EST 2022
LINC00960 regulates cell proliferation and glycolysis in pancreatic cancer through the miR-326-3p/TUFT1/AKT-mTOR axis.
The Kaohsiung journal of medical sciences
Zhou B,Lei JH,Wang Q,Qu TF,Cha LC,Zhan HX,Liu SL,Hu X,Sun CD,Cao JY,Qiu FB,Guo WD
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Western Blot
Thu Dec 01 00:00:00 EST 2022
Inhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ mice.
Cell death & disease
Farini A,Tripodi L,Villa C,Napolitano F,Strati F,Molinaro D,Facciotti F,Cassani B,Torrente Y
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Western Blot
Sat Nov 19 00:00:00 EST 2022
Diane-35 and Metformin Induce Autophagy and Apoptosis in Polycystic Ovary Syndrome Women with Early-Stage Endometrial Carcinoma.
Genes
Liu Y,Wang Y,Yao D,Chen X,Zhang F,Feng Y,Li X
PA5-34663 was used in Western Blot to support the use of Diane-35 and metformin combination therapy for patients with PCOS and early EC.
Wed Jan 12 00:00:00 EST 2022
Ontogenetic Changes in the Expression of the Lin28 Protein in the Rat Hypothalamic Tuberal Nuclei.
International journal of molecular sciences
Anfimova PA,Pankrasheva LG,Moiseev KY,Shirina ES,Porseva VV,Masliukov PM
PA5-34663 was used in ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to show for the first time the presence of Lin28-immunoreactive (IR) neurons in the ventromedial nucleus (VMH) and their absence in the dorsomedial and arcuate nuclei in all studied animals.
Thu Nov 03 00:00:00 EDT 2022
ACSL4 contributes to sevoflurane-induced ferroptotic neuronal death in SH-SY5Y cells via the 5' AMP-activated protein kinase/mammalian target of rapamycin pathway.
Annals of translational medicine
Cheng L,Zhu X,Liu Y,Zhu K,Lin K,Li F
PA5-34663 was used in Western Blot to show that downregulation of ACSL4 restrained sev-induced ferroptotic cell death via AMPK/mTOR signaling, providing the basis for an approach to alleviate sev-induced postoperative cognitive dysfunction (POCD).
Wed Sep 01 00:00:00 EDT 2021
ACSL4 contributes to sevoflurane-induced ferroptotic neuronal death in SH-SY5Y cells via the 5' AMP-activated protein kinase/mammalian target of rapamycin pathway.
Annals of translational medicine
Cheng L,Zhu X,Liu Y,Zhu K,Lin K,Li F
PA5-34663 was used in Western Blot to show that downregulation of ACSL4 restrained sev-induced ferroptotic cell death via AMPK/mTOR signaling, providing the basis for an approach to alleviate sev-induced postoperative cognitive dysfunction (POCD).
Wed Sep 01 00:00:00 EDT 2021
Implications of cell division cycle associated 4 on the Wilm's tumor cells viability via AKT/mTOR signaling pathway.
Renal failure
Li S,Qin C,Chen Y,Wei D,Tan Z,Meng J
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Western Blot
Wed Dec 01 00:00:00 EST 2021
Selective Deletion of the Mechanistic Target of Rapamycin From the Renal Collecting Duct Principal Cell in Mice Down-Regulates the Epithelial Sodium Channel.
Frontiers in physiology
Chen B,Fluitt MB,Brown AL,Scott S,Gadicherla A,Ecelbarger CM
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Western Blot
Wed Dec 20 00:00:00 EST 2023
Selective Deletion of the Mechanistic Target of Rapamycin From the Renal Collecting Duct Principal Cell in Mice Down-Regulates the Epithelial Sodium Channel.
Frontiers in physiology
Chen B,Fluitt MB,Brown AL,Scott S,Gadicherla A,Ecelbarger CM
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Western Blot
Wed Dec 20 00:00:00 EST 2023
MM-129 as a Novel Inhibitor Targeting PI3K/AKT/mTOR and PD-L1 in Colorectal Cancer.
Cancers
Hermanowicz JM,Pawlak K,Sieklucka B,Czarnomysy R,Kwiatkowska I,Kazberuk A,Surazynski A,Mojzych M,Pawlak D
PA5-34663 was used in Western Blot to examine the pharmacodynamics of MM-129 as a novel promising drug candidate against colon cancer.
Sat Jun 26 00:00:00 EDT 2021
MM-129 as a Novel Inhibitor Targeting PI3K/AKT/mTOR and PD-L1 in Colorectal Cancer.
Cancers
Hermanowicz JM,Pawlak K,Sieklucka B,Czarnomysy R,Kwiatkowska I,Kazberuk A,Surazynski A,Mojzych M,Pawlak D
PA5-34663 was used in Western Blot to examine the pharmacodynamics of MM-129 as a novel promising drug candidate against colon cancer.
Sat Jun 26 00:00:00 EDT 2021
Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice.
International journal of molecular sciences
Paštar V,Lozić M,Kelam N,Filipović N,Bernard B,Katsuyama Y,Vukojević K
PA5-34663 was used in ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to emphasize connexins as a goal-keeper in the maintenance of liver homeostasis and Cxs and Panxs could serve as potential biomarkers and drug targets in liver pathology and diagnostics.
Sat Oct 02 00:00:00 EDT 2021
Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.
Molecular cell
Hekman RM,Hume AJ,Goel RK,Abo KM,Huang J,Blum BC,Werder RB,Suder EL,Paul I,Phanse S,Youssef A,Alysandratos KD,Padhorny D,Ojha S,Mora-Martin A,Kretov D,Ash PEA,Verma M,Zhao J,Patten JJ,Villacorta-Martin C,Bolzan D,Perea-Resa C,Bullitt E,Hinds A,Tilston-Lunel A,Varelas X,Farhangmehr S,Braunschweig U,Kwan JH,McComb M,Basu A,Saeed M,Perissi V,Burks EJ,Layne MD,Connor JH,Davey R,Cheng JX,Wolozin BL,Blencowe BJ,Wuchty S,Lyons SM,Kozakov D,Cifuentes D,Blower M,Kotton DN,Wilson AA,Mühlberger E,Emili A
PA5-34663 was used in Functional network inference to perform a quantitative phosphoproteomic survey of induced pluripotent stem cell-derived AT2s infected with SARS-CoV-2 at air-liquid interface, to understand the mechanisms driving infection and pathology.
Thu Dec 17 00:00:00 EST 2020
Interaction of YAP1 and mTOR promotes bladder cancer progression.
International journal of oncology
Xu M,Gu M,Zhou J,Da J,Wang Z
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Western Blot
Wed Jan 01 00:00:00 EST 2020
Interaction of YAP1 and mTOR promotes bladder cancer progression.
International journal of oncology
Xu M,Gu M,Zhou J,Da J,Wang Z
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Western Blot
Wed Jan 01 00:00:00 EST 2020
Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells.
Nature communications
Choi SC,Titov AA,Abboud G,Seay HR,Brusko TM,Roopenian DC,Salek-Ardakani S,Morel L
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Immunofluorescence
Mon Oct 22 00:00:00 EDT 2018
In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip.
Proceedings of the National Academy of Sciences of the United States of America
Wu X,Schneider N,Platen A,Mitra I,Blazek M,Zengerle R,Schüle R,Meier M
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Miscellaneous
Tue Jul 19 00:00:00 EDT 2016
In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip.
Proceedings of the National Academy of Sciences of the United States of America
Wu X,Schneider N,Platen A,Mitra I,Blazek M,Zengerle R,Schüle R,Meier M
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Miscellaneous
Tue Jul 19 00:00:00 EDT 2016
In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip.
Proceedings of the National Academy of Sciences of the United States of America
Wu X,Schneider N,Platen A,Mitra I,Blazek M,Zengerle R,Schüle R,Meier M
Published figure using mTOR polyclonal antibody (Product # PA5-34663) in Miscellaneous
Tue Jul 19 00:00:00 EDT 2016
