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Product Details
MA1-20231
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Storage conditions
Shipping conditions
RRID
Product Specific Information
MA1-20231 detects talin in rat, Xenopus laevis and human samples. Does not react with fish.
MA1-20231 has been successfully used in immunocytochemistry, immunofluorescence, immunoprecipitation and Western blot procedures.
The MA1-20231 immunogen is cytoskeletal protein talin, purified from chicken gizzard.
Store at 4ºC short term. For extended storage, store at -20ºC, avoiding freeze/thaw cycles.
Target Information
Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
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