Product References
Drug target validation in primary human natural killer cells using CRISPR RNP.
Journal of leukocyte biology
Rautela J,Surgenor E,Huntington ND
13-3600 was used in Western Blot to show an efficient approach to genetically edit human NK cells by electroporation and CRISPR-Cas9 ribonucleoprotein complexes.
Thu Oct 01 00:00:00 EDT 2020
Deficiency of core fucosylation activates cellular signaling dependent on FLT3 expression in a Ba/F3 cell system.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Duan C,Fukuda T,Isaji T,Qi F,Yang J,Wang Y,Takahashi S,Gu J
13-3600 was used in Western Blotting to show that the N-glycan structures on wild type (WT), internal tandem duplication (ITD), and tyrosine kinase domain (TKD) mutants of FLT3 were different.
Sat Feb 01 00:00:00 EST 2020
Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo.
Cancers
Maranto C,Udhane V,Jia J,Verma R,Müller-Newen G,LaViolette PS,Pereckas M,Sabharwal L,Terhune S,Pattabiraman N,Njar VCO,Imig JD,Wang L,Nevalainen MT
13-3600 was used in Immunoprecipitation to support further optimization of IST5 for oral bioavailability for clinical development for therapies for solid tumors, hematological and myeloproliferative disorders.
Wed Nov 18 00:00:00 EST 2020
Identification of STAT3 and STAT5 proteins in the rat suprachiasmatic nucleus and the Day/Night difference in astrocytic STAT3 phosphorylation in response to lipopolysaccharide.
Journal of neuroscience research
Moravcová S,Červená K,Pačesová D,Bendová Z
13-3600 was used in immunohistochemistry (free floating) to examine the daily rhythm of STAT3 protein.
Fri Jan 01 00:00:00 EST 2016
Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells.
PloS one
Ushiki T,Huntington ND,Glaser SP,Kiu H,Georgiou A,Zhang JG,Metcalf D,Nicola NA,Roberts AW,Alexander WS
13-3600 was used in Western Blotting to study the role of the Suppressors of Cytokine Signalling (SOCS) proteins, SOCS1 and SOCS3, in the prevent of inflammatory disease.
Wed Aug 02 00:00:00 EDT 2017
DNA methylation and transcription in a distal region upstream from the bovine AlphaS1 casein gene after once or twice daily milking.
PloS one
Nguyen M,Boutinaud M,Pétridou B,Gabory A,Pannetier M,Chat S,Bouet S,Jouneau L,Jaffrezic F,Laloë D,Klopp C,Brun N,Kress C,Jammes H,Charlier M,Devinoy E
13-3600 was used in EMSA to investigate the role of CpG methylation in milk production
Thu Jun 25 00:00:00 EDT 2015
A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance.
Journal of cell science
Elsarraj HS,Hong Y,Valdez K,Carletti M,Salah SM,Raimo M,Taverna D,Prochasson P,Bharadwaj U,Tweardy DJ,Christenson LK,Behbod F
13-3600 was used in western blot to demonstrate that miR46b promotes the maintenance of pregnancy-derived mammary luminal alveolar progenitors.
Sat Jun 01 00:00:00 EDT 2013
Preoperative irradiation for the prevention of heterotopic ossification induces local inflammation in humans.
Bone
Hoff P,Rakow A,Gaber T,Hahne M,Sentürk U,Strehl C,Fangradt M,Schmidt-Bleek K,Huscher D,Winkler T,Matziolis D,Matziolis G,Badakhshi H,Burmester GR,Duda GN,Perka C,Buttgereit F
13-3600 was used in western blot to test if preoperative irradiation impacts local immune components.
Mon Jul 01 00:00:00 EDT 2013
Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters.
Nucleic acids research
Barros P,Lam EW,Jordan P,Matos P
Published figure using STAT5 alpha monoclonal antibody (Product # 13-3600) in Western Blot
Sat Sep 01 00:00:00 EDT 2012
Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters.
Nucleic acids research
Barros P,Lam EW,Jordan P,Matos P
Published figure using STAT5 alpha monoclonal antibody (Product # 13-3600) in Western Blot
Sat Sep 01 00:00:00 EDT 2012
Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters.
Nucleic acids research
Barros P,Lam EW,Jordan P,Matos P
Published figure using STAT5 alpha monoclonal antibody (Product # 13-3600) in Western Blot
Sat Sep 01 00:00:00 EDT 2012
A humanized pattern of aromatase expression is associated with mammary hyperplasia in mice.
Endocrinology
Zhao H,Pearson EK,Brooks DC,Coon JS,Chen D,Demura M,Zhang M,Clevenger CV,Xu X,Veenstra TD,Chatterton RT,DeMayo FJ,Bulun SE
13-3600 was used in western blot to use transgenic humanized aromatase mice to study the link between aromatase expression in mammary adipose tissue and breast pathology.
Fri Jun 01 00:00:00 EDT 2012
Prolactin signalling in the mouse hypothalamus is primarily mediated by signal transducer and activator of transcription factor 5b but not 5a.
Journal of neuroendocrinology
Yip SH,Eguchi R,Grattan DR,Bunn SJ
13-3600 was used in immunohistochemistry - free floating and western blot to report that STAT5b and not STAT5a is the primary mediator prolactin signaling in the hypothalamus.
Sat Dec 01 00:00:00 EST 2012
Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers.
Molecular endocrinology (Baltimore, Md.)
Kabotyanski EB,Huetter M,Xian W,Rijnkels M,Rosen JM
13-3600 was used in ChIP assay to examine the effects of prolactin and glucocorticoids on chromatin remodeling and transcriptional activation in mammary epithelial cells
Sun Oct 01 00:00:00 EDT 2006
Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility.
Cancer research
Silver DL,Naora H,Liu J,Cheng W,Montell DJ
Sat May 15 00:00:00 EDT 2004
Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility.
Cancer research
Silver DL,Naora H,Liu J,Cheng W,Montell DJ
Sat May 15 00:00:00 EDT 2004
Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility.
Cancer research
Silver DL,Naora H,Liu J,Cheng W,Montell DJ
Sat May 15 00:00:00 EDT 2004
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5.
The Journal of biological chemistry
Gewinner C,Hart G,Zachara N,Cole R,Beisenherz-Huss C,Groner B
Fri Jan 30 00:00:00 EST 2004
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5.
The Journal of biological chemistry
Gewinner C,Hart G,Zachara N,Cole R,Beisenherz-Huss C,Groner B
Fri Jan 30 00:00:00 EST 2004
Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.
Immunity
Chong MM,Cornish AL,Darwiche R,Stanley EG,Purton JF,Godfrey DI,Hilton DJ,Starr R,Alexander WS,Kay TW
Tue Apr 01 00:00:00 EST 2003
STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta.
The EMBO journal
Xu M,Nie L,Kim SH,Sun XH
Published figure using STAT5 alpha monoclonal antibody (Product # 13-3600) in Western Blot
Mon Feb 17 00:00:00 EST 2003
STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta.
The EMBO journal
Xu M,Nie L,Kim SH,Sun XH
Published figure using STAT5 alpha monoclonal antibody (Product # 13-3600) in Western Blot
Mon Feb 17 00:00:00 EST 2003
STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta.
The EMBO journal
Xu M,Nie L,Kim SH,Sun XH
Published figure using STAT5 alpha monoclonal antibody (Product # 13-3600) in Western Blot
Mon Feb 17 00:00:00 EST 2003
Hormone-induced modifications of the chromatin structure surrounding upstream regulatory regions conserved between the mouse and rabbit whey acidic protein genes.
The Biochemical journal
Millot B,Montoliu L,Fontaine ML,Mata T,Devinoy E
13-3600 was used in Electrophoretic mobility shift assay to study the upstream regulatory regions of the mouse and rabbit whey acidic protein (WAP) genes to elucidate fully the mechanisms controlling WAP gene expression.
Thu May 15 00:00:00 EDT 2003
Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain.
Molecular biology of the cell
Saharinen P,Vihinen M,Silvennoinen O
Tue Apr 01 00:00:00 EST 2003
Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain.
Molecular biology of the cell
Saharinen P,Vihinen M,Silvennoinen O
Tue Apr 01 00:00:00 EST 2003
Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells.
The Journal of biological chemistry
Cornish AL,Chong MM,Davey GM,Darwiche R,Nicola NA,Hilton DJ,Kay TW,Starr R,Alexander WS
Fri Jun 20 00:00:00 EDT 2003
Cooperation among Stat1, glucocorticoid receptor, and PU.1 in transcriptional activation of the high-affinity Fc gamma receptor I in monocytes.
Journal of immunology (Baltimore, Md. : 1950)
Aittomäki S,Pesu M,Groner B,Jänne OA,Palvimo JJ,Silvennoinen O
13-3600 was used in immunoprecipitation and western blot to characterize the functional cooperation between IFN-gamma and dexamethasone in the induction of the high-affinity Fc gamma receptor I in monocytes.
Thu Jun 01 00:00:00 EDT 2000
