Product References
Remifentanil modulates the TLR4‑mediated MMP‑9/TIMP1 balance and NF‑κB/STAT3 signaling in LPS‑induced A549 cells.
Experimental and therapeutic medicine
Chang J,Zhang W
MA1-13042 was used in ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to show that remifentanil downregulated TLR4 to reduce MMP-9/TIMP1 imbalance to inhibit inflammatory dysfunction in LPS-treated A549 cells, by regulating NF-κB/STAT3 signaling.
Wed Feb 01 00:00:00 EST 2023
Diospyros lotus leaf extract and its main component myricitrin regulate pruritus through the inhibition of astrocyte activation.
Experimental and therapeutic medicine
Shin JY,Cho BO,Park JH,Kang ES,Kim YS,Jang SI
MA1-13042 was used in Western Blotting to suggest that Diospyros lotus leaf extract and myricetin can be used as oral therapeutic agents for the treatment and management of pruritus.
Sat Jul 01 00:00:00 EDT 2023
Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma.
EMBO molecular medicine
Sorger H,Dey S,Vieyra-Garcia PA,Pölöske D,Teufelberger AR,de Araujo ED,Sedighi A,Graf R,Spiegl B,Lazzeri I,Braun T,Garces de Los Fayos Alonso I,Schlederer M,Timelthaler G,Kodajova P,Pirker C,Surbek M,Machtinger M,Graier T,Perchthaler I,Pan Y,Fink-Puches R,Cerroni L,Ober J,Otte M,Albrecht JD,Tin G,Abdeldayem A,Manaswiyoungkul P,Olaoye OO,Metzelder ML,Orlova A,Berger W,Wobser M,Nicolay JP,André F,Nguyen VA,Neubauer HA,Fleck R,Merkel O,Herling M,Heitzer E,Gunning PT,Kenner L,Moriggl R,Wolf P
MA1-13042 was used in Western Blot and Immunohistochemistry to identify key vulnerable nodes in Leukemic cutaneous T-cell lymphomas (L-CTCL).
Wed Dec 07 00:00:00 EST 2022
Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma.
EMBO molecular medicine
Sorger H,Dey S,Vieyra-Garcia PA,Pölöske D,Teufelberger AR,de Araujo ED,Sedighi A,Graf R,Spiegl B,Lazzeri I,Braun T,Garces de Los Fayos Alonso I,Schlederer M,Timelthaler G,Kodajova P,Pirker C,Surbek M,Machtinger M,Graier T,Perchthaler I,Pan Y,Fink-Puches R,Cerroni L,Ober J,Otte M,Albrecht JD,Tin G,Abdeldayem A,Manaswiyoungkul P,Olaoye OO,Metzelder ML,Orlova A,Berger W,Wobser M,Nicolay JP,André F,Nguyen VA,Neubauer HA,Fleck R,Merkel O,Herling M,Heitzer E,Gunning PT,Kenner L,Moriggl R,Wolf P
MA1-13042 was used in Western Blot and Immunohistochemistry to identify key vulnerable nodes in Leukemic cutaneous T-cell lymphomas (L-CTCL).
Wed Dec 07 00:00:00 EST 2022
Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling.
iScience
Wang R,Wang Y,Liao G,Chen B,Panettieri RA,Penn RB,Tang DD
Published figure using STAT3 monoclonal antibody (Product # MA1-13042) in Immunocytochemistry
Fri Feb 18 00:00:00 EST 2022
Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling.
iScience
Wang R,Wang Y,Liao G,Chen B,Panettieri RA,Penn RB,Tang DD
Published figure using STAT3 monoclonal antibody (Product # MA1-13042) in Immunocytochemistry
Fri Feb 18 00:00:00 EST 2022
Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling.
iScience
Wang R,Wang Y,Liao G,Chen B,Panettieri RA,Penn RB,Tang DD
Published figure using STAT3 monoclonal antibody (Product # MA1-13042) in Immunocytochemistry
Fri Feb 18 00:00:00 EST 2022
Prevention of Testicular Damage by Indole Derivative MMINA via Upregulated StAR and CatSper Channels with Coincident Suppression of Oxidative Stress and Inflammation: In Silico and In Vivo Validation.
Antioxidants (Basel, Switzerland)
Afsar T,Razak S,Trembley JH,Khan K,Shabbir M,Almajwal A,Alruwaili NW,Ijaz MU
MA1-13042 was used in Western Blotting to reveal that MMINA boosted the antioxidant defense mechanism, restored the levels of fertility hormones, and suppressed histomorphological alterations.
Wed Oct 19 00:00:00 EDT 2022
Prevention of Testicular Damage by Indole Derivative MMINA via Upregulated StAR and CatSper Channels with Coincident Suppression of Oxidative Stress and Inflammation: In Silico and In Vivo Validation.
Antioxidants (Basel, Switzerland)
Afsar T,Razak S,Trembley JH,Khan K,Shabbir M,Almajwal A,Alruwaili NW,Ijaz MU
MA1-13042 was used in Western Blotting to reveal that MMINA boosted the antioxidant defense mechanism, restored the levels of fertility hormones, and suppressed histomorphological alterations.
Wed Oct 19 00:00:00 EDT 2022
Role of Oncostatin M in the Pathogenesis of Vernal Keratoconjunctivitis: Focus on the Barrier Function of the Epithelium and Interleukin-33 Production by Fibroblasts.
Investigative ophthalmology & visual science
Ninomiya I,Yamatoya K,Mashimo K,Matsuda A,Usui-Ouchi A,Araki Y,Ebihara N
Published figure using STAT3 monoclonal antibody (Product # MA1-13042) in Western Blot
Thu Dec 01 00:00:00 EST 2022
Penta-O-Galloyl-β-D-Glucose in Pistacia integerrima Targets AMPK-ULK1 and ERK/STAT3 Signaling Axes to Induce ROS-Independent Autophagic Cell Death in Human Lung Cancer Cells.
Frontiers in pharmacology
Balkrishna A,Mulay VP,Verma S,Srivastava J,Lochab S,Varshney A
MA1-13042 was used in ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to propose PGG as a potential AMPK activator and STAT3 inhibitor that can be exploited further in developing adjuvant chemotherapeutics against lung cancer.
Sat Aug 06 00:00:00 EDT 2022
Novel TPR::ROS1 Fusion Gene Activates MAPK, PI3K and JAK/STAT Signaling in an Infant-type Pediatric Glioma.
Cancer genomics & proteomics
Deland L,Keane S,Bontell TO,Fagman H,Sjögren H,Lind AE,Carén H,Tisell M,Nilsson JA,Ejeskär K,Sabel M,Abel F
MA1-13042 was used in Western Blotting to identify and characterize a novel TPR::ROS1 fusion gene in an infant-type hemispheric glioma, shedding light on the activated oncogenic pathways and potential targeted therapies.
Thu Nov 03 00:00:00 EDT 2022
Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations.
EBioMedicine
Silva Oliveira Junior M,Schira-Heinen J,Reiche L,Han S,de Amorim VCM,Lewen I,Gruchot J,Göttle P,Akkermann R,Azim K,Küry P
MA1-13042 was used in Immunohistochemistry to analyse demyelination and remyelination related effects on astrocytes and stem cell niches and study the consequences of medrysone application on myelin repair, and astrocyte polarization.
Thu Sep 01 00:00:00 EDT 2022
miRNAs Potentially Involved in Post Lung Transplant-Obliterative Bronchiolitis: The Role of miR-21-5p.
Cells
Bozzini S,Pandolfi L,Rossi E,Inghilleri S,Zorzetto M,Ferrario G,Di Carlo S,Politano G,De Silvestri A,Frangipane V,Porzio M,Kessler R,Calabrese F,Meloni F,Morbini P
Published figure using STAT3 monoclonal antibody (Product # MA1-13042) in Western Blot
Sat Mar 20 00:00:00 EDT 2021
Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer.
Cancer medicine
Rashid M,Ali R,Almuzzaini B,Song H,AlHallaj A,Abdulkarim AA,Mohamed Baz O,Al Zahrani H,Mustafa Sabeena M,Alharbi W,Hussein M,Boudjelal M
MA1-13042 was used in Western Blotting to report the discovery of a mutation in the CSF2RB gene of a breast cancer patient and the cell line KAIMRC1.
Mon Nov 01 00:00:00 EDT 2021
Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer.
Cancer medicine
Rashid M,Ali R,Almuzzaini B,Song H,AlHallaj A,Abdulkarim AA,Mohamed Baz O,Al Zahrani H,Mustafa Sabeena M,Alharbi W,Hussein M,Boudjelal M
MA1-13042 was used in Western Blotting to report the discovery of a mutation in the CSF2RB gene of a breast cancer patient and the cell line KAIMRC1.
Mon Nov 01 00:00:00 EDT 2021
Inhibition of IL-6 in the LCWE Mouse Model of Kawasaki Disease Inhibits Acute Phase Reactant Serum Amyloid A but Fails to Attenuate Vasculitis.
Frontiers in immunology
Porritt RA,Chase Huizar C,Dick EJ,Kumar S,Escalona R,Gomez AC,Marek-Iannucci S,Noval Rivas M,Patterson J,Forsthuber TG,Arditi M,Gorelik M
MA1-13042 was used in Immunohistochemistry to show that both STAT3 and IL-6 were dispensable for disease development indicating they may be bystanders of inflammation.
Mon Sep 20 00:00:00 EDT 2021
Inhibition of IL-6 in the LCWE Mouse Model of Kawasaki Disease Inhibits Acute Phase Reactant Serum Amyloid A but Fails to Attenuate Vasculitis.
Frontiers in immunology
Porritt RA,Chase Huizar C,Dick EJ,Kumar S,Escalona R,Gomez AC,Marek-Iannucci S,Noval Rivas M,Patterson J,Forsthuber TG,Arditi M,Gorelik M
MA1-13042 was used in Immunohistochemistry to show that both STAT3 and IL-6 were dispensable for disease development indicating they may be bystanders of inflammation.
Mon Sep 20 00:00:00 EDT 2021
The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis.
The Journal of clinical investigation
Müller A,Dickmanns A,Resch C,Schäkel K,Hailfinger S,Dobbelstein M,Schulze-Osthoff K,Kramer D
MA1-13042 was used in Chromatin immunoprecipitation to find a hyperactivation of the CDK4/6-EZH2 pathway in human and mouse psoriatic skin lesions.
Mon Nov 02 00:00:00 EST 2020
MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling.
mBio
Fu B,Xue W,Zhang H,Zhang R,Feldman K,Zhao Q,Zhang S,Shi L,Pavani KC,Nian W,Lin X,Wu H
Published figure using STAT3 monoclonal antibody (Product # MA1-13042) in Western Blot
Tue Jun 02 00:00:00 EDT 2020
MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling.
mBio
Fu B,Xue W,Zhang H,Zhang R,Feldman K,Zhao Q,Zhang S,Shi L,Pavani KC,Nian W,Lin X,Wu H
Published figure using STAT3 monoclonal antibody (Product # MA1-13042) in Western Blot
Tue Jun 02 00:00:00 EDT 2020
Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch.
Cell reports
Mishra SK,Wheeler JJ,Pitake S,Ding H,Jiang C,Fukuyama T,Paps JS,Ralph P,Coyne J,Parkington M,DeBrecht J,Ehrhardt-Humbert LC,Cruse GP,Bäumer W,Ji RR,Ko MC,Olivry T
MA1-13042 was used in Western Blotting to show that periostin, abundantly expressed in the skin of patients with atopic dermatitis (AD), induces itch in mice, dogs, and monkeys.
Tue Apr 07 00:00:00 EDT 2020
Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation.
Nature
Niu J,Sun Y,Chen B,Zheng B,Jarugumilli GK,Walker SR,Hata AN,Mino-Kenudson M,Frank DA,Wu X
Published figure using STAT3 monoclonal antibody (Product # MA1-13042) in Immunocytochemistry
Sun Sep 01 00:00:00 EDT 2019
Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation.
Nature
Niu J,Sun Y,Chen B,Zheng B,Jarugumilli GK,Walker SR,Hata AN,Mino-Kenudson M,Frank DA,Wu X
Published figure using STAT3 monoclonal antibody (Product # MA1-13042) in Immunocytochemistry
Sun Sep 01 00:00:00 EDT 2019
Effects of cell-cell crosstalk on gene expression patterns in a cell model of renal cell carcinoma lung metastasis.
International journal of oncology
Kaminska K,Czarnecka AM,Khan MI,Fendler W,Klemba A,Krasowski P,Bartnik E,Szczylik C
MA1-13042 was used in Western Blotting to study the contribution of cell-cell communication in the development of the metastatic niche in renal cell carcinoma.
Thu Mar 01 00:00:00 EST 2018
Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides.
Blood
McGirt LY,Jia P,Baerenwald DA,Duszynski RJ,Dahlman KB,Zic JA,Zwerner JP,Hucks D,Dave U,Zhao Z,Eischen CM
MA1-13042 was used in western blot to identify factors that contribute to mycosis fungoides pathogenesis
Thu Jul 23 00:00:00 EDT 2015
An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells.
PloS one
Campia I,Buondonno I,Castella B,Rolando B,Kopecka J,Gazzano E,Ghigo D,Riganti C
MA1-13042 was used in western blot to analyze multidrug resistant human cancer cells and autocrime cytokine/JAK/STAT-signaling induces kynurenin synthesis
Tue Feb 02 00:00:00 EST 2016
Patients with T⁺/low NK⁺ IL-2 receptor γ chain deficiency have differentially-impaired cytokine signaling resulting in severe combined immunodeficiency.
European journal of immunology
Fuchs S,Rensing-Ehl A,Erlacher M,Vraetz T,Hartjes L,Janda A,Rizzi M,Lorenz MR,Gilmour K,de Saint-Basile G,Roifman CM,Cheuk S,Gennery A,Thrasher AJ,Fuchs I,Schwarz K,Speckmann C,Ehl S
MA1-13042 was used in Western Blot to show that IL2RG(R222C) causes a consistently severe clinical phenotype that is not predicted by the variable and moderate impairment of T-cell immunity or TREC analysis.
Wed Oct 01 00:00:00 EDT 2014
FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription.
Cell death and differentiation
Dong L,Li Y,Cao J,Liu F,Pier E,Chen J,Xu Z,Chen C,Wang RA,Cui R
MA1-13042 was used in western blot to identify the regulation and function of the paired box 3 gene.
Sun Apr 01 00:00:00 EDT 2012
