Product References
Proteomic Profiling of Chemotherapy Responses in FOLFOX-Resistant Colorectal Cancer Cells.
International journal of molecular sciences
Tam SY,Islam Khan MZ,Chen JY,Yip JH,Yan HY,Tam TY,Law HK
PA1-091 was used in Western Blotting to compare the difference of chemotherapy responses between FOLFOX-resistant and wild-type colorectal cancer cells by proteomic profiling to suggest novel treatment targets.
Thu Jun 08 00:00:00 EDT 2023
Regulation of serine palmitoyl-transferase and Rac1-Nox2 signaling in diabetic retinopathy.
Scientific reports
Alka K,Mohammad G,Kowluru RA
Published figure using RAC1 polyclonal antibody (Product # PA1-091) in Immunocytochemistry
Thu Oct 06 00:00:00 EDT 2022
Neutrophils interact with cholangiocytes to cause cholestatic changes in alcoholic hepatitis.
Gut
Takeuchi M,Vidigal PT,Guerra MT,Hundt MA,Robert ME,Olave-Martinez M,Aoki S,Khamphaya T,Kersten R,Kruglov E,de la Rosa Rodriguez R,Banales JM,Nathanson MH,Weerachayaphorn J
PA1-091 was used in Western Blotting to examine whether bile ducts participate in the pathogenesis of Alcoholic hepatitis.
Mon Feb 01 00:00:00 EST 2021
RAC1 plays an essential role in estrogen receptor alpha function in breast cancer cells.
Oncogene
Sun J,Gaidosh G,Xu Y,Mookhtiar A,Man N,Cingaram PR,Blumenthal E,Shiekhattar R,Goka ET,Nimer SD,Lippman ME
Published figure using RAC1 polyclonal antibody (Product # PA1-091) in Western Blot
Fri Oct 01 00:00:00 EDT 2021
RAC1 plays an essential role in estrogen receptor alpha function in breast cancer cells.
Oncogene
Sun J,Gaidosh G,Xu Y,Mookhtiar A,Man N,Cingaram PR,Blumenthal E,Shiekhattar R,Goka ET,Nimer SD,Lippman ME
Published figure using RAC1 polyclonal antibody (Product # PA1-091) in Western Blot
Fri Oct 01 00:00:00 EDT 2021
Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction.
Frontiers in cell and developmental biology
Misra S,Ghatak S,Moreno-Rodriguez RA,Norris RA,Hascall VC,Markwald RR
PA1-091 was used in Western Blot to examine whether filamin A has a cross-talk with periostin/signaling that promotes remodeling of postnatal heart valves into mature leaflets.
Thu Feb 09 00:00:00 EST 2023
Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction.
Frontiers in cell and developmental biology
Misra S,Ghatak S,Moreno-Rodriguez RA,Norris RA,Hascall VC,Markwald RR
PA1-091 was used in Western Blot to examine whether filamin A has a cross-talk with periostin/signaling that promotes remodeling of postnatal heart valves into mature leaflets.
Thu Feb 09 00:00:00 EST 2023
Endoplasmic Reticulum Stress Induces CAP2 Expression Promoting Epithelial-Mesenchymal Transition in Liver Cancer Cells.
Molecules and cells
Yoon S,Shin B,Woo HG
PA1-091 was used in Western Blot to suggest that ER stress induces CAP2 expression promoting EMT in liver cancers cells.
Tue Aug 31 00:00:00 EDT 2021
NecroX-5 Can Suppress Melanoma Metastasis by Reducing the Expression of Rho-Family GTPases.
Journal of clinical medicine
Moon GT,Lee JH,Jeong SH,Jin SW,Park YM
PA1-091 was used in Western Blotting to demonstrate that NX-5 can suppress melanoma metastasis by reducing the expression of Rho-family GTPases.
Fri Jun 25 00:00:00 EDT 2021
NecroX-5 Can Suppress Melanoma Metastasis by Reducing the Expression of Rho-Family GTPases.
Journal of clinical medicine
Moon GT,Lee JH,Jeong SH,Jin SW,Park YM
PA1-091 was used in Western Blotting to demonstrate that NX-5 can suppress melanoma metastasis by reducing the expression of Rho-family GTPases.
Fri Jun 25 00:00:00 EDT 2021
EMT-Induced Cell-Mechanical Changes Enhance Mitotic Rounding Strength.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Hosseini K,Taubenberger A,Werner C,Fischer-Friedrich E
Published figure using RAC1 polyclonal antibody (Product # PA1-091) in Western Blot
Thu Oct 01 00:00:00 EDT 2020
Adaptor Protein p66Shc: A Link Between Cytosolic and Mitochondrial Dysfunction in the Development of Diabetic Retinopathy.
Antioxidants & redox signaling
Mishra M,Duraisamy AJ,Bhattacharjee S,Kowluru RA
PA1-091 was used in Immunoprecipitation to investigate the role of p66Shc in the development of diabetic retinopathy.
Wed May 01 00:00:00 EDT 2019
Functional Regulation of an Oxidative Stress Mediator, Rac1, in Diabetic Retinopathy.
Molecular neurobiology
Mohammad G,Duraisamy AJ,Kowluru A,Kowluru RA
PA1-091 was used in Immunocytochemistry-immunoflourescence to investigate the mechanisms of Rac1 activation in the development of diabetic retinopathy.
Sun Dec 01 00:00:00 EST 2019
Activation of endothelial ras-related C3 botulinum toxin substrate 1 (Rac1) improves post-stroke recovery and angiogenesis via activating Pak1 in mice.
Experimental neurology
Bu F,Min JW,Munshi Y,Lai YJ,Qi L,Urayama A,McCullough LD,Li J
PA1-091 was used in Immunohistochemistry-immunofluorescence to examine the functional role of endothelial Ras-related C3 botulinum toxin substrate 1(Rac1) in post-stroke recovery and angiogenesis.
Sun Dec 01 00:00:00 EST 2019
Comparative analysis of viral entry for Asian and African lineages of Zika virus.
Virology
Rinkenberger N,Schoggins JW
PA1-091 was used in Western Blotting to contribute new insight into the ZIKV entry process and suggest that divergent ZIKV strains enter cells in a highly conserved manner.
Mon Jul 01 00:00:00 EDT 2019
Cannabinoid receptor 2 agonist attenuates blood‑brain barrier damage in a rat model of intracerebral hemorrhage by activating the Rac1 pathway.
International journal of molecular medicine
Wang Z,Li Y,Cai S,Li R,Cao G
PA1-091 was used in Western Blotting to study the effect of cannabinoid receptor 2 agonist (CNR2) JWH133 on blood brain barrier integrity and its underlying mechanism.
Thu Nov 01 00:00:00 EDT 2018
AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis.
The Journal of clinical investigation
Li N,Xue W,Yuan H,Dong B,Ding Y,Liu Y,Jiang M,Kan S,Sun T,Ren J,Pan Q,Li X,Zhang P,Hu G,Wang Y,Wang X,Li Q,Qin J
PA1091 was used in immunohistochemistry to demonstrate that WHSC1 drives indolent PTEN-null tumors to become metastatic prostate cancer
Mon Apr 03 00:00:00 EDT 2017
AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis.
The Journal of clinical investigation
Li N,Xue W,Yuan H,Dong B,Ding Y,Liu Y,Jiang M,Kan S,Sun T,Ren J,Pan Q,Li X,Zhang P,Hu G,Wang Y,Wang X,Li Q,Qin J
PA1091 was used in immunohistochemistry to demonstrate that WHSC1 drives indolent PTEN-null tumors to become metastatic prostate cancer
Mon Apr 03 00:00:00 EDT 2017
Di-n-butyl phthalate exposure negatively influences structural and functional neuroplasticity via Rho-GTPase signaling pathways.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ding Y,Lu L,Xuan C,Han J,Ye S,Cao T,Chen W,Li A,Zhang X
PA1091 was used in western blot to develop and examine a mouse model of chronic di-n-butyl phthalate exposure
Sat Jul 01 00:00:00 EDT 2017
RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat Model.
Reproductive sciences (Thousand Oaks, Calif.)
Ubba V,Soni UK,Chadchan S,Maurya VK,Kumar V,Maurya R,Chaturvedi H,Singh R,Dwivedi A,Jha RK
PA1091 was used in flow cytometry and western blot to determine the expression and localization of RHOG in normal and polycystic rat ovaries
Mon May 01 00:00:00 EDT 2017
C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons.
Nature neuroscience
Sivadasan R,Hornburg D,Drepper C,Frank N,Jablonka S,Hansel A,Lojewski X,Sterneckert J,Hermann A,Shaw PJ,Ince PG,Mann M,Meissner F,Sendtner M
PA1-091X was used in western blot to elucidate the mechanism by which intronic hexanucleotide expansions in C9ORF72 contribute to amyotrophic lateral sclerosis
Thu Dec 01 00:00:00 EST 2016
RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment.
Oncogene
Hein AL,Post CM,Sheinin YM,Lakshmanan I,Natarajan A,Enke CA,Batra SK,Ouellette MM,Yan Y
PA1-091 was used in western blot to study promotion of survival of breast cancer cells in response to hyper-fractionated radiation treatment by RAC1 GTPase
Thu Dec 08 00:00:00 EST 2016
MicroRNA-27a Inhibits Cell Migration and Invasion of Fibroblast-Like Synoviocytes by Targeting Follistatin-Like Protein 1 in Rheumatoid Arthritis.
Molecules and cells
Shi DL,Shi GR,Xie J,Du XZ,Yang H
PA1-091 was used in western blot to investigate the effects of miR-27a on cell migration and invasion in fibroblast-like synoviocytes from rheumatoid arthritis patients
Wed Aug 31 00:00:00 EDT 2016
The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor.
Peptides
Girola N,Matsuo AL,Figueiredo CR,Massaoka MH,Farias CF,Arruda DC,Azevedo RA,Monteiro HP,Resende-Lara PT,Cunha RL,Polonelli L,Travassos LR
PA1-091X was used in western blot to ascertain the mechanism of action of the Rb9 peptide
Tue Nov 01 00:00:00 EDT 2016
The NarE protein of Neisseria gonorrhoeae catalyzes ADP-ribosylation of several ADP-ribose acceptors despite an N-terminal deletion.
FEMS microbiology letters
Rodas PI,Álamos-Musre AS,Álvarez FP,Escobar A,Tapia CV,Osorio E,Otero C,Calderón IL,Fuentes JA,Gil F,Paredes-Sabja D,Christodoulides M
PA1-091X was used in western blot to determine the enzymatic activity of NarE of Neisseria gonorrhoeae
Thu Sep 01 00:00:00 EDT 2016