Product References
Long non-coding RNA MEG3 promotes tumor necrosis factor-alpha induced oxidative stress and apoptosis in interstitial cells of cajal via targeting the microRNA-21 /I-kappa-B-kinase beta axis.
Bioengineered
Li J,Bai J,Tuerdi N,Liu K
M621B was used in Western Blot to conclude that MEG3 mediates inflammation, oxidative stress and apoptosis in TNF-α-treated ICC via the miR-21/IKKB-NF-κB axis.
Fri Apr 01 00:00:00 EDT 2022
Long non-coding RNA MEG3 promotes tumor necrosis factor-alpha induced oxidative stress and apoptosis in interstitial cells of cajal via targeting the microRNA-21 /I-kappa-B-kinase beta axis.
Bioengineered
Li J,Bai J,Tuerdi N,Liu K
M621B was used in Western Blot to conclude that MEG3 mediates inflammation, oxidative stress and apoptosis in TNF-α-treated ICC via the miR-21/IKKB-NF-κB axis.
Fri Apr 01 00:00:00 EDT 2022
Therapeutic effect of Resveratrol in the treatment of osteoarthritis via the MALAT1/miR-9/NF-κB signaling pathway.
Experimental and therapeutic medicine
Zhang G,Zhang H,You W,Tang X,Li X,Gong Z
Published figure using IL-6 monoclonal antibody (Product # M621B) in Western Blot
Sun Mar 01 00:00:00 EST 2020
Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children.
Frontiers in immunology
Siebert JN,Hamann L,Verolet CM,Gameiro C,Grillet S,Siegrist CA,Posfay-Barbe KM
M621B was used in an ELISA assay to asses whether a defect somewhere along this toll-like receptor signally pathways increases susceptibility to recurrent pneumococcal low respiratory tract infections.
Mon Sep 16 00:00:00 EDT 2019
Kaposi's sarcoma-associated herpesvirus kaposin B induces unique monophosphorylation of STAT3 at serine 727 and MK2-mediated inactivation of the STAT3 transcriptional repressor TRIM28.
Journal of virology
King CA
Published figure using IL-6 monoclonal antibody (Product # M621B) in ELISA
Thu Aug 01 00:00:00 EDT 2013
Th1 responses to beta-amyloid in young humans convert to regulatory IL-10 responses in Down syndrome and Alzheimer's disease.
Neurobiology of aging
Loewenbrueck KF,Tigno-Aranjuez JT,Boehm BO,Lehmann PV,Tary-Lehmann M
M621B was used in ELISA to study the role of Th1 responses to beta-amyloid in Down syndrome and Alzheimer disease
Fri Oct 01 00:00:00 EDT 2010
Development of an 8-plex Luminex assay to detect swine cytokines for vaccine development: assessment of immunity after porcine reproductive and respiratory syndrome virus (PRRSV) vaccination.
Vaccine
Lawson S,Lunney J,Zuckermann F,Osorio F,Nelson E,Welbon C,Clement T,Fang Y,Wong S,Kulas K,Christopher-Hennings J
M621B was used in ELISA to develop a multiplex Luminex assay to measure pig cytokines for vaccine development
Mon Jul 19 00:00:00 EDT 2010
Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: does variable inhibition of interleukin-6 production limit effectiveness in vivo?
Arthritis and rheumatism
Page TH,Brown A,Timms EM,Foxwell BM,Ray KP
M621B was used in ELISA to investigate the role of p38 kinase in rheumatoid arthritis synovial membranes
Mon Nov 01 00:00:00 EDT 2010
A component of polysaccharide peptidoglycan complex on Lactobacillus induced an improvement of murine model of inflammatory bowel disease and colitis-associated cancer.
Immunology
Matsumoto S,Hara T,Nagaoka M,Mike A,Mitsuyama K,Sako T,Yamamoto M,Kado S,Takada T
M621B was used in ELISA to investigate the role of Lactobacillus polysaccharide peptidoglycan complex in chronic intestinal inflammatory disorders
Tue Sep 01 00:00:00 EDT 2009
Human mast cell activation with virus-associated stimuli leads to the selective chemotaxis of natural killer cells by a CXCL8-dependent mechanism.
Blood
Burke SM,Issekutz TB,Mohan K,Lee PW,Shmulevitz M,Marshall JS
M621B was used in ELISA to study the role of human mast cells in the recruitment of natural killer cells
Sun Jun 15 00:00:00 EDT 2008
IgE modulates neutrophil survival in asthma: role of mitochondrial pathway.
Journal of immunology (Baltimore, Md. : 1950)
Saffar AS,Alphonse MP,Shan L,Hayglass KT,Simons FE,Gounni AS
M621B was used in ELISA to study the role of mitochondrial pathway in neutrophil survival
Thu Feb 15 00:00:00 EST 2007
Protein microarray platform for the multiplex analysis of biomarkers in human sera.
Journal of immunological methods
Urbanowska T,Mangialaio S,Zickler C,Cheevapruk S,Hasler P,Regenass S,Legay F
M621B was used in ELISA to develop a protein microarray platform for the multiplex analysis of biomarkers in human sera
Fri Oct 20 00:00:00 EDT 2006
Probiotic Lactobacillus-induced improvement in murine chronic inflammatory bowel disease is associated with the down-regulation of pro-inflammatory cytokines in lamina propria mononuclear cells.
Clinical and experimental immunology
Matsumoto S,Hara T,Hori T,Mitsuyama K,Nagaoka M,Tomiyasu N,Suzuki A,Sata M
M621B was used in ELISA to study the effect of Lactobacillus casei strain Shirota on the production of interleukin 6 in LPS-stimulated murine large intestinal lamina propria mononuclear cells
Wed Jun 01 00:00:00 EDT 2005
Long-term treatment with etanercept significantly reduces the number of proinflammatory cytokine-secreting peripheral blood mononuclear cells in patients with rheumatoid arthritis.
Rheumatology (Oxford, England)
Schotte H,Schlüter B,Willeke P,Mickholz E,Schorat MA,Domschke W,Gaubitz M
M621B was used in ELISA to study the effect of etanercept treatment on proinflammatory cytokine-secreting peripheral blood mononuclear cells in rheumatoid arthritic patients
Sun Aug 01 00:00:00 EDT 2004
Tumor-infiltrating lymphocyte secretion of IL-6 antagonizes tumor-derived TGF-beta 1 and restores the lymphokine-activated killing activity.
Journal of immunology (Baltimore, Md. : 1950)
Hsiao YW,Liao KW,Hung SW,Chu RM
M621B was used in ELISA to investigate the function of interleukin-6 from tumor-infiltrating lymphocytes
Sun Feb 01 00:00:00 EST 2004
Interleukin-6 fused to an anti-idiotype antibody in a vaccine increases the specific humoral immune response against CA125+ (MUC-16) ovarian cancer.
Cancer research
Reinartz S,Hombach A,Köhler S,Schlebusch H,Wallwiener D,Abken H,Wagner U
M621B was used in western blot to study the capacity of IL-6 fused to an anti-idiotype antibody in a vaccine to increase the specific humoral immune response against CA125+ ovarian cancer
Sun Jun 15 00:00:00 EDT 2003
Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women.
International archives of allergy and immunology
Tsunoda M,Litonjua AA,Kuniak MP,Weiss ST,Satoh T,Guevarra L,Tollerud DJ
M621B was used in ELISA to investigate the relationship between serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women
Sat Feb 01 00:00:00 EST 2003
A nonsteroidal glucocorticoid receptor antagonist.
Molecular endocrinology (Baltimore, Md.)
Miner JN,Tyree C,Hu J,Berger E,Marschke K,Nakane M,Coghlan MJ,Clemm D,Lane B,Rosen J
M621B was used in immunocytochemistry to characterize a potent nonsteroidal antagonist against glucocorticoid receptor
Wed Jan 01 00:00:00 EST 2003
Ambient air particulates stimulate alveolar macrophages of smokers to promote differentiation of myeloid precursor cells.
Experimental lung research
Suwa T,Hogg JC,Vincent R,Mukae H,Fujii T,van Eeden SF
M621B was used in ELISA to test if factors released from human alveolar macrophages exposed to air pollution particles accelerate the maturation of granulocyte precursors
Tue Jul 09 00:00:00 EDT 2002
Release of vasoactive cytokines by antibody-enhanced dengue virus infection of a human mast cell/basophil line.
Journal of virology
King CA,Marshall JS,Alshurafa H,Anderson R
M621B was used in ELISA to investigate the role of mast cells/basophils in dengue pathogenesis
Tue Aug 01 00:00:00 EDT 2000
Regulation of interleukin-12 by complement receptor 3 signaling.
The Journal of experimental medicine
Marth T,Kelsall BL
M621B was used in ELISA to assess the interferon-alpha production in peripheral blood mononuclear cell
Mon Jun 02 00:00:00 EDT 1997
Sustained high levels of circulating chaperoned interleukin-6 after active specific cancer immunotherapy.
Blood
May LT,Patel K,García D,Ndubuisi MI,Ferrone S,Mittelman A,Mackiewicz A,Sehgal PB
M621B was used in ELISA to investigate the changes of interleukin 6 level in patients with cancer immunotherapy
Thu Sep 15 00:00:00 EDT 1994