Product References
Crosstalk between TBK1/IKKε and the type I interferon pathway contributes to tubulointerstitial inflammation and kidney tubular injury.
Frontiers in pharmacology
Córdoba-David G,García-Giménez J,Cardoso Castelo-Branco R,Carrasco S,Cannata P,Ortiz A,Ramos AM
PA5-20390 was used in Immunohistochemistry to tI-IFNs, TWEAK, and LPS engage interrelated proinflammatory and antiviral responses in tubular cells. Moreover, inhibition of TBK1/IKKε with amlexanox, and IFNAR targeting, may protect from tubulointerstitial kidney injury.
Fri Nov 18 00:00:00 EST 2022
Crosstalk between TBK1/IKKε and the type I interferon pathway contributes to tubulointerstitial inflammation and kidney tubular injury.
Frontiers in pharmacology
Córdoba-David G,García-Giménez J,Cardoso Castelo-Branco R,Carrasco S,Cannata P,Ortiz A,Ramos AM
PA5-20390 was used in Immunohistochemistry to tI-IFNs, TWEAK, and LPS engage interrelated proinflammatory and antiviral responses in tubular cells. Moreover, inhibition of TBK1/IKKε with amlexanox, and IFNAR targeting, may protect from tubulointerstitial kidney injury.
Fri Nov 18 00:00:00 EST 2022
1,25(OH)2 D3 blocks IFNβ production through regulating STING in epithelial layer of oral lichen planus.
Journal of cellular and molecular medicine
Ge X,Wang Y,Xie H,Li R,Zhang F,Zhao B,Du J
PA5-20390 was used in Western Blotting to find 1,25(OH)2 D3 regulates STING and IFNβ through a mechanism controlled by the hypoxia-inducible factor-1α (HIF-1α)-GATA1 axis.
Fri Jul 01 00:00:00 EDT 2022
dsRNA Induced IFNβ-MMP13 Axis Drives Corneal Wound Healing.
Investigative ophthalmology & visual science
Lan X,Zhang W,Zhu J,Huang H,Mo K,Guo H,Zhu L,Liu J,Li M,Wang L,Liu C,Ji J,Ouyang H
PA5-20390 was used in Immunohistochemistry, Western Blot, Immunhistochemistry (Paraffin) to identify MMP13 as a downstream effector of IFNβ where its expression promotes LSC proliferation and enhances corneal epithelial reconstruction in vivo.
Tue Feb 01 00:00:00 EST 2022
In vitro and in vivo correlation of skin and cellular responses to nucleic acid delivery.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Bosnjak M,Znidar K,Sales Conniff A,Jesenko T,Markelc B,Semenova N,Tur J,Kohena K,Kranjc Brezar S,Heller L,Cemazar M
PA5-20390 was used in Immunohistochemistry-frozen immunofluorescence to investigate the immune response in skin cells, including keratinocytes, fibroblasts, and macrophages, following plasmid DNA electrotransfer, revealing upregulation of DNA sensors and cytokines.
Wed Jun 01 00:00:00 EDT 2022
Inhibition of interferon-signalling halts cancer-associated fibroblast-dependent protection of breast cancer cells from chemotherapy.
British journal of cancer
Broad RV,Jones SJ,Teske MC,Wastall LM,Hanby AM,Thorne JL,Hughes TA
Published figure using IFN beta polyclonal antibody (Product # PA5-20390) in Immunohistochemistry
Mon Mar 01 00:00:00 EST 2021
Inhibition of interferon-signalling halts cancer-associated fibroblast-dependent protection of breast cancer cells from chemotherapy.
British journal of cancer
Broad RV,Jones SJ,Teske MC,Wastall LM,Hanby AM,Thorne JL,Hughes TA
Published figure using IFN beta polyclonal antibody (Product # PA5-20390) in Immunohistochemistry
Mon Mar 01 00:00:00 EST 2021
Klotho deficiency intensifies hypoxia-induced expression of IFN-α/β through upregulation of RIG-I in kidneys.
PloS one
Urabe A,Doi S,Nakashima A,Ike T,Morii K,Sasaki K,Doi T,Arihiro K,Masaki T
Published figure using IFN beta polyclonal antibody (Product # PA5-20390) in ELISA
Mon Nov 29 00:00:00 EST 2021
Klotho deficiency intensifies hypoxia-induced expression of IFN-α/β through upregulation of RIG-I in kidneys.
PloS one
Urabe A,Doi S,Nakashima A,Ike T,Morii K,Sasaki K,Doi T,Arihiro K,Masaki T
Published figure using IFN beta polyclonal antibody (Product # PA5-20390) in ELISA
Mon Nov 29 00:00:00 EST 2021
IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer.
Cell reports
Ka NL,Lim GY,Hwang S,Kim SS,Lee MO
PA5-20390 was used in Immunohistochemistry to suggest that type-I IFNs and IFI16 could offer potential therapeutic strategies for TNBC.
Tue Dec 21 00:00:00 EST 2021
Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity.
Science advances
Liang J,Wang H,Ding W,Huang J,Zhou X,Wang H,Dong X,Li G,Chen E,Zhou F,Fan H,Xia J,Shen B,Cai D,Lan P,Jiang H,Ling J,Cheng Z,Liu X,Sun J
PA5-20390 was used in Immunohistochemistry to offer a rational design of an effective immunotherapy combination regimen to convert uninflamed "cold" tumors into "hot" tumors, addressing the major challenges immunotherapies faced.
Sat Aug 01 00:00:00 EDT 2020
IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus.
Science translational medicine
Shao S,Tsoi LC,Sarkar MK,Xing X,Xue K,Uppala R,Berthier CC,Zeng C,Patrick M,Billi AC,Fullmer J,Beamer MA,Perez-White B,Getsios S,Schuler A,Voorhees JJ,Choi S,Harms P,Kahlenberg JM,Gudjonsson JE
PA5-20390 was used in Immunohistochemistry to study the role and mechanisms of IFN-γ in Lichen planus pathogenesis and provides evidence for the therapeutic use of JAK inhibitors to limit cell-mediated cytotoxicity in patients with Lichen planus.
Wed Sep 25 00:00:00 EDT 2019
RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection.
PLoS pathogens
Downey J,Pernet E,Coulombe F,Allard B,Meunier I,Jaworska J,Qureshi S,Vinh DC,Martin JG,Joubert P,Divangahi M
Published figure using IFN beta polyclonal antibody (Product # PA5-20390) in Immunofluorescence
Sat Apr 01 00:00:00 EDT 2017
Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum.
Journal of lipid research
Mukherjee P,Hough G,Chattopadhyay A,Navab M,Fogelman HR,Meriwether D,Williams K,Bensinger S,Moller T,Faull KF,Lusis AJ,Iruela-Arispe ML,Bostrom KI,Tontonoz P,Reddy ST,Fogelman AM
Published figure using IFN beta polyclonal antibody (Product # PA5-20390) in ELISA
Tue Aug 01 00:00:00 EDT 2017
Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum.
Journal of lipid research
Mukherjee P,Hough G,Chattopadhyay A,Navab M,Fogelman HR,Meriwether D,Williams K,Bensinger S,Moller T,Faull KF,Lusis AJ,Iruela-Arispe ML,Bostrom KI,Tontonoz P,Reddy ST,Fogelman AM
Published figure using IFN beta polyclonal antibody (Product # PA5-20390) in ELISA
Tue Aug 01 00:00:00 EDT 2017
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.
Proceedings of the National Academy of Sciences of the United States of America
Demaria O,De Gassart A,Coso S,Gestermann N,Di Domizio J,Flatz L,Gaide O,Michielin O,Hwu P,Petrova TV,Martinon F,Modlin RL,Speiser DE,Gilliet M
PA5-20390 was used in immunohistochemistry to analyze the function of STING in activating tumor endothelial cells and antitumor immunity
Tue Dec 15 00:00:00 EST 2015
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.
Proceedings of the National Academy of Sciences of the United States of America
Demaria O,De Gassart A,Coso S,Gestermann N,Di Domizio J,Flatz L,Gaide O,Michielin O,Hwu P,Petrova TV,Martinon F,Modlin RL,Speiser DE,Gilliet M
PA5-20390 was used in immunohistochemistry to analyze the function of STING in activating tumor endothelial cells and antitumor immunity
Tue Dec 15 00:00:00 EST 2015
